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Gene: Slc10a3 (solute carrier family 10, member 3) Rattus norvegicus

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Symbol:

Slc10a3

Name:

solute carrier family 10, member 3

RGD ID:

1563513

Description:

Predicted to enable bile acid:sodium symporter activity. Predicted to be involved in bile acid and bile salt transport. Predicted to act upstream of or within response to retinoic acid. Predicted to be located in membrane. Orthologous to human SLC10A3 (solute carrier family 10 member 3); INTERACTS WITH 3,4-methylenedioxymethamphetamine; bisphenol A; cobalt dichloride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC501665; P3 protein; similar to protein P3; solute carrier family 10 (sodium/bile acid cotransporter family), member 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC10A3 (solute carrier family 10 member 3)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Slc10a3 (solute carrier family 10 (sodium/bile acid cotransporter family), member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc10a3 (solute carrier family 10 member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC10A3 (solute carrier family 10 member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC10A3 (solute carrier family 10 member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc10a3 (solute carrier family 10 member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC10A3 (solute carrier family 10 member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC10A3 (solute carrier family 10 member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc10a3 (solute carrier family 10 member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SLC10A3 (solute carrier family 10 member 3)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Slc10a3 (solute carrier family 10 (sodium/bile acid cotransporter family), member 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	slc10a3 (solute carrier family 10 member 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG11655	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y71G10AR.4	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG9903	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	slc10a3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	157,306,043 - 157,309,849 (-)	NCBI		GRCr8
mRatBN7.2	X	152,154,757 - 152,158,563 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	152,151,076 - 152,162,958 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	154,295,882 - 154,299,688 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	157,858,689 - 157,862,495 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	155,530,915 - 155,534,721 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	156,335,385 - 156,340,256 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	156,336,450 - 156,340,234 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	152,075,855 - 152,080,393 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	160,234,831 - 160,238,637 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	135,738,093 - 135,741,899 (+)	NCBI		Celera
Cytogenetic Map	X	q37	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adrenoleukodystrophy (ISO)

autistic disorder (ISO)

autosomal hemophilia A (ISO)

Barth syndrome (ISO)

cerebral creatine deficiency syndrome 1 (ISO)

dyskeratosis congenita (ISO)

Emery-Dreifuss muscular dystrophy (ISO)

factor VIII deficiency (ISO)

favism (ISO)

immunodeficiency 33 (ISO)

paraplegia (ISO)

periventricular nodular heterotopia (ISO)

severe congenital encephalopathy due to MECP2 mutation (ISO)

Splenomegaly (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,4-methylenedioxymethamphetamine (EXP)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

carbon nanotube (ISO)

CGP 52608 (ISO)

cobalt dichloride (EXP)

copper(II) chloride (ISO)

diazinon (ISO)

Dibutyl phosphate (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

folic acid (ISO)

gefitinib (ISO)

menadione (ISO)

naphthalene (ISO)

okadaic acid (ISO)

paracetamol (ISO)

potassium chromate (ISO)

resveratrol (ISO)

sunitinib (ISO)

triclosan (ISO)

urethane (ISO)

valproic acid (ISO)

zidovudine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bile acid and bile salt transport (IBA)

response to retinoic acid (IEA,ISO)

sodium ion transport (IEA)

transmembrane transport (IEA)

Cellular Component

membrane (IEA)

Molecular Function

bile acid:sodium symporter activity (IBA)

symporter activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:18400104

Genomics

Comparative Map Data

Slc10a3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	157,306,043 - 157,309,849 (-)	NCBI		GRCr8
mRatBN7.2	X	152,154,757 - 152,158,563 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	152,151,076 - 152,162,958 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	154,295,882 - 154,299,688 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	157,858,689 - 157,862,495 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	155,530,915 - 155,534,721 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	156,335,385 - 156,340,256 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	156,336,450 - 156,340,234 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	152,075,855 - 152,080,393 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	160,234,831 - 160,238,637 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	135,738,093 - 135,741,899 (+)	NCBI		Celera
Cytogenetic Map	X	q37	NCBI

SLC10A3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	154,487,311 - 154,490,629 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	154,487,306 - 154,490,690 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	153,715,650 - 153,718,968 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	153,368,842 - 153,372,189 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	153,279,351 - 153,282,699	NCBI
Celera	X	153,876,701 - 153,880,053 (-)	NCBI		Celera
Cytogenetic Map	X	q28	NCBI
HuRef	X	142,292,818 - 142,296,107 (-)	NCBI		HuRef
CHM1_1	X	153,627,295 - 153,630,647 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	152,723,820 - 152,727,138 (-)	NCBI		T2T-CHM13v2.0

Slc10a3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	73,412,823 - 73,416,955 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	73,412,823 - 73,416,955 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	74,369,217 - 74,373,349 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	74,369,217 - 74,373,349 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	71,614,556 - 71,618,595 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	70,621,937 - 70,625,976 (-)	NCBI		MGSCv36	mm8
Celera	X	65,623,032 - 65,627,071 (-)	NCBI		Celera
Cytogenetic Map	X	A7.3	NCBI
cM Map	X	38.0	NCBI

Slc10a3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955580	1,002,029 - 1,005,673 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955580	1,002,029 - 1,005,673 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC10A3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	154,461,710 - 154,465,039 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	154,465,314 - 154,468,644 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	143,929,086 - 143,932,406 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	153,800,354 - 153,803,680 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	153,800,354 - 153,803,653 (-)	Ensembl	panpan1.1		panPan2

SLC10A3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	122,197,049 - 122,201,103 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	122,197,289 - 122,200,219 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
ROS_Cfam_1.0	X	125,338,706 - 125,342,598 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	125,338,711 - 125,342,615 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	121,107,704 - 121,111,596 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	123,622,782 - 123,626,674 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	123,384,553 - 123,388,446 (-)	NCBI		UU_Cfam_GSD_1.0

Slc10a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	119,504,209 - 119,508,247 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936809	1,241,986 - 1,246,266 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936809	1,241,980 - 1,245,986 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC10A3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	125,010,131 - 125,011,928 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	125,010,128 - 125,013,992 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	143,571,480 - 143,575,323 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC10A3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	128,736,793 - 128,741,400 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	128,736,991 - 128,738,424 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	66,725,602 - 66,729,241 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc10a3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624946	959,051 - 960,502 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624946	958,850 - 961,163 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	34
Count of miRNA genes:	34
Interacting mature miRNAs:	34
Transcripts:	ENSRNOT00000056315
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
634346	Insul4	Insulin level QTL 4	0		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	X	126975089	152453651	Rat
10059603	Bw174	Body weight QTL 174	3.4	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	X	113937816	152453651	Rat

Markers in Region

Slc10a3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	152,155,056 - 152,155,927 (-)	MAPPER	mRatBN7.2
Rnor_6.0	X	156,339,086 - 156,339,956	NCBI	Rnor6.0
Rnor_5.0	1	152,079,223 - 152,080,093	UniSTS	Rnor5.0
RGSC_v3.4	X	160,237,467 - 160,238,337	UniSTS	RGSC3.4
Celera	1	135,740,729 - 135,741,599	UniSTS
Cytogenetic Map	X	q37	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001024368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008773611	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC094668	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC086556	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474099	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000082124 ⟹ ENSRNOP00000075188

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	152,154,759 - 152,158,579 (-)	Ensembl
Rnor_6.0 Ensembl	X	156,336,450 - 156,340,234 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095027 ⟹ ENSRNOP00000087740

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	152,151,076 - 152,158,705 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104026 ⟹ ENSRNOP00000083345

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	152,151,237 - 152,162,958 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107598 ⟹ ENSRNOP00000083069

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	152,154,793 - 152,158,539 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116820 ⟹ ENSRNOP00000092346

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	152,151,076 - 152,158,705 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119658 ⟹ ENSRNOP00000078591

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	152,151,242 - 152,158,507 (-)	Ensembl

RefSeq Acc Id:

NM_001024368 ⟹ NP_001019539

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	157,306,043 - 157,309,849 (-)	NCBI
mRatBN7.2	X	152,154,757 - 152,158,563 (-)	NCBI
Rnor_6.0	X	156,336,450 - 156,340,256 (+)	NCBI
Rnor_5.0	1	152,075,855 - 152,080,393 (+)	NCBI
RGSC_v3.4	X	160,234,831 - 160,238,637 (+)	RGD
Celera	1	135,738,093 - 135,741,899 (+)	NCBI

Sequence:

show sequence

GCCGCTGCTGGTGAGGAGCTCTGTAGTCGCGGAAGCAGTTACCTTACTTTGGTTTTCCTGCCTC
CTTCTTCATCAGTGAGACTCAAGACTGGACCAGGGCCTCCAGGGAAAAGTCCTGAGATCAAGGA
AGAAAACAAAGGACCAGGACCTTCCCATGGACCCTTCTCAGGACATTCCAACAGCACAAGCAAA
GGTGTTCCCCTAATACCCAAGAAGCCTGAAAACACTATCCTTTGTGAAGTGCCATGGTGGTCAG
GAAAAGCAGAGATAGCTCCCAGCAGTTGCCTGGCCTGAGAGGACAGGGTGGTTGTACAGGTTTT
GTAGGCATGCTTGGAACTGCCCTGCTGTTCATCAGCTTGACATGGGGGGCCCAAGTGATGGCCA
GTGCCAACATCAGCACTGCTCTGGGCCACAGAATTGGTCACTATTTGAGTATTGGGGATGGCTC
AGTGACAGAGTTTGATTTCCCTGAGAAGAGTGAGGGTATCATTGTGATCTCTAGCCAGTATACT
GGACAGGCCAACGGGACAGGCCCCAGCCCCACACTGAGGGTTATATCACTGGACACAGAGGTGC
TGACCGTTAAAAATGTAAGTGCCATAACCTGGGGCAGTGGAGGCGGCTTCGTGGTGAGCATCCA
CTCGGGTCTGGCTGGGCTGGCCCCACTCCACCTCCAGCTCATGGATTCCCATGAGGCCCCACCC
CTACTGATCGAAGAACGGAGAGATTTCTGCATCAGGGTGTCACCTGCTGAAGACCTCTCTTCTG
CCCTCAACGCCAACTTGGGCCACTTCTCAGAGAATCCAATACTCTACCTGCTTCTGCCTCTTAT
CTTTGTCAACAAGTGTTCATTTGGGTGCAAAGTGGAACTTGAAGTTTTGAAGGAGCTCCTACAG
AGCCCCCAACCCATGCTGTTGGGCCTCTTGGGCCAGTTTCTGGTCATGCCCTTCTATGCTTTCC
TGATGGCCAAAGTCTTCATGCTACCCAAGGCCTTAGCTCTGGGCCTCATCATTACCTGCTCATC
ACCTGGTGGTGGAGGGAGCTACCTCTTCAGTCTCCTCCTTGGAGGAGATGTCACCCTGGCCATC
TCCATGACTTTCATCTCAACAGTAGCTGCCACTGGTTTCCTGCCACTCTCATCAGCCATCTACA
GCTACCTTCTCAGCATCCATGAAACACTCCACGTGCCCATCTCCAAGATACTGGGGACCCTGCT
GTTCATTGCCATCCCCATAGCAGCAGGTGTAGTTATCAAGTCCAAACTCCCCAAGTTCTCTGAG
CTACTGCTACAGGTCATCAAGCCCTTCAGCTTTGTACTTCTCCTGGGTGGCCTGTTCCTAGCCT
ACCACATGGGGGTCTTCATCCTAGTGGGAGTCAGGTTACCCATTGTACTGGTGGGTTTCACAGT
GCCTCTTGTTGGCCTCTTGGTGGGCTACAGCCTGGCCATCTGCCTGAAACTGCCAGTGGCCCAG
CGGCGAACAGTCAGCATTGAGGTAGGGGTGCAAAACAGCCTGTTAGCCTTAGCCATGCTACAGC
TGTCTCTGCGCCGCCTTCAAGCAGACTATGCCTCTCAGGCCCCTTTCATTGTGGCACTGAGTGG
TACCTCCGAGATGCTGGTGTTGGTTATTGGCCAGTTCATCTACAGCAGCTTTTTTCCTGTTCCC
TGAGCCCCCCTGGCTCAAGTTTTATAACCCCCAGCCCCCATACTCCTCTCTTGTATACCAAAGG
CCTTTAGTTCTCATGCACTATGCACTCAGACAAATCCAGGCTTATTTTTTTACTCTTCCCCCCA
GCTTTCAGTGCCAAAGAGGCCATGCTGAGTTAGATAGTTGGGTATTTCCCAGAAATATATTTCA
ATAAAAAAAAAACAAAAGCAAAAAAAAAAAAAAAAAAAAAAAAA

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Protein Sequences


Protein RefSeqs	NP_001019539	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH86556	(Get FASTA)	NCBI Sequence Viewer
	EDL84968	(Get FASTA)	NCBI Sequence Viewer
	EDL84969	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000075188
	ENSRNOP00000075188.1
	ENSRNOP00000078591.1
	ENSRNOP00000083069.1
	ENSRNOP00000083345.1
	ENSRNOP00000087740.1
	ENSRNOP00000092346.1

RefSeq Acc Id:

NP_001019539 ⟸ NM_001024368

- UniProtKB:

Q5RJP6 (UniProtKB/TrEMBL), A0A0G2K9Z0 (UniProtKB/TrEMBL), A0A8I5ZW70 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVVRKSRDSSQQLPGLRGQGGCTGFVGMLGTALLFISLTWGAQVMASANISTALGHRIGHYLSI
GDGSVTEFDFPEKSEGIIVISSQYTGQANGTGPSPTLRVISLDTEVLTVKNVSAITWGSGGGFV
VSIHSGLAGLAPLHLQLMDSHEAPPLLIEERRDFCIRVSPAEDLSSALNANLGHFSENPILYLL
LPLIFVNKCSFGCKVELEVLKELLQSPQPMLLGLLGQFLVMPFYAFLMAKVFMLPKALALGLII
TCSSPGGGGSYLFSLLLGGDVTLAISMTFISTVAATGFLPLSSAIYSYLLSIHETLHVPISKIL
GTLLFIAIPIAAGVVIKSKLPKFSELLLQVIKPFSFVLLLGGLFLAYHMGVFILVGVRLPIVLV
GFTVPLVGLLVGYSLAICLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPFIV
ALSGTSEMLVLVIGQFIYSSFFPVP

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Ensembl Acc Id:

ENSRNOP00000075188 ⟸ ENSRNOT00000082124

Ensembl Acc Id:

ENSRNOP00000083345 ⟸ ENSRNOT00000104026

Ensembl Acc Id:

ENSRNOP00000078591 ⟸ ENSRNOT00000119658

Ensembl Acc Id:

ENSRNOP00000083069 ⟸ ENSRNOT00000107598

Ensembl Acc Id:

ENSRNOP00000087740 ⟸ ENSRNOT00000095027

Ensembl Acc Id:

ENSRNOP00000092346 ⟸ ENSRNOT00000116820

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5RJP6-F1-model_v2	AlphaFold	Q5RJP6	1-473	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13702040

Promoter ID:

EPDNEW_R12564

Type:

multiple initiation site

Name:

Slc10a3_1

Description:

solute carrier family 10, member 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	156,336,441 - 156,336,501	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563513	AgrOrtholog
BioCyc Gene	G2FUF-621	BioCyc
Ensembl Genes	ENSRNOG00000060580	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000082124	ENTREZGENE
	ENSRNOT00000082124.2	UniProtKB/TrEMBL
	ENSRNOT00000095027.1	UniProtKB/TrEMBL
	ENSRNOT00000104026.1	UniProtKB/TrEMBL
	ENSRNOT00000107598.1	UniProtKB/TrEMBL
	ENSRNOT00000116820.1	UniProtKB/TrEMBL
	ENSRNOT00000119658.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1530.20	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7304843	IMAGE-MGC_LOAD
InterPro	BilAc/Na_symport	UniProtKB/TrEMBL
	Bilac:Na_transpt	UniProtKB/TrEMBL
	Na+/solute_symporter_sf	UniProtKB/TrEMBL
KEGG Report	rno:501665	UniProtKB/TrEMBL
MGC_CLONE	MGC:105543	IMAGE-MGC_LOAD
NCBI Gene	501665	ENTREZGENE
PANTHER	P3 PROTEIN	UniProtKB/TrEMBL
	SODIUM-BILE ACID COTRANSPORTER	UniProtKB/TrEMBL
Pfam	SBF	UniProtKB/TrEMBL
PhenoGen	Slc10a3	PhenoGen
RatGTEx	ENSRNOG00000060580	RatGTEx
UniProt	A0A0G2K9Z0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZW70	ENTREZGENE, UniProtKB/TrEMBL
	Q5RJP6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-08-02	Slc10a3	solute carrier family 10, member 3	Slc10a3	solute carrier family 10 (sodium/bile acid cotransporter family), member 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-05	Slc10a3	solute carrier family 10 (sodium/bile acid cotransporter family), member 3	LOC501665	similar to protein P3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	LOC501665	similar to protein P3			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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