Farsb (phenylalanyl-tRNA synthetase subunit beta) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Farsb (phenylalanyl-tRNA synthetase subunit beta) Rattus norvegicus
Analyze
Symbol: Farsb
Name: phenylalanyl-tRNA synthetase subunit beta
RGD ID: 1303210
Description: Predicted to enable phenylalanine-tRNA ligase activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation and protein heterotetramerization. Predicted to be part of phenylalanine-tRNA ligase complex. Orthologous to human FARSB (phenylalanyl-tRNA synthetase subunit beta); PARTICIPATES IN phenylketonuria pathway; tyrosinemia type II pathway; tyrosinemia type III pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Farslb; MGC94847; phenylalanine--tRNA ligase beta subunit; phenylalanine-tRNA synthetase-like, beta subunit; phenylalanyl-tRNA synthetase beta chain; phenylalanyl-tRNA synthetase, beta subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2979,887,852 - 79,947,082 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl979,887,842 - 79,947,045 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx988,317,637 - 88,376,818 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0993,430,056 - 93,490,053 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0991,829,079 - 91,888,260 (-)NCBIRnor_WKY
Rnor_6.0984,324,456 - 84,383,674 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl984,324,442 - 84,383,687 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0984,083,341 - 84,142,523 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4977,806,573 - 77,865,757 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1977,989,996 - 78,049,176 (-)NCBI
Celera977,396,205 - 77,455,355 (-)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-phenylbutyric acid  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
clozapine  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
dibenzo[a,l]pyrene  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
fenthion  (ISO)
flutamide  (EXP)
formaldehyde  (ISO)
glafenine  (EXP)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
menadione  (ISO)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
pirinixic acid  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tanespimycin  (ISO)
thioacetamide  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:19946888   PMID:20223217  


Genomics

Comparative Map Data
Farsb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2979,887,852 - 79,947,082 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl979,887,842 - 79,947,045 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx988,317,637 - 88,376,818 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0993,430,056 - 93,490,053 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0991,829,079 - 91,888,260 (-)NCBIRnor_WKY
Rnor_6.0984,324,456 - 84,383,674 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl984,324,442 - 84,383,687 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0984,083,341 - 84,142,523 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4977,806,573 - 77,865,757 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1977,989,996 - 78,049,176 (-)NCBI
Celera977,396,205 - 77,455,355 (-)NCBICelera
Cytogenetic Map9q33NCBI
FARSB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382222,566,899 - 222,656,092 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2222,566,899 - 222,656,092 (-)EnsemblGRCh38hg38GRCh38
GRCh372223,431,618 - 223,520,811 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362223,144,406 - 223,229,071 (-)NCBINCBI36Build 36hg18NCBI36
Build 342223,260,760 - 223,346,310NCBI
Celera2217,204,356 - 217,288,733 (-)NCBICelera
Cytogenetic Map2q36.1NCBI
HuRef2215,289,904 - 215,374,144 (-)NCBIHuRef
CHM1_12223,442,666 - 223,527,209 (-)NCBICHM1_1
T2T-CHM13v2.02223,052,236 - 223,141,156 (-)NCBIT2T-CHM13v2.0
Farsb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39178,394,595 - 78,465,534 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl178,394,612 - 78,465,534 (-)EnsemblGRCm39 Ensembl
GRCm38178,417,958 - 78,488,897 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl178,417,975 - 78,488,897 (-)EnsemblGRCm38mm10GRCm38
MGSCv37178,421,411 - 78,485,421 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36178,307,983 - 78,371,993 (-)NCBIMGSCv36mm8
Celera178,895,232 - 78,957,096 (-)NCBICelera
Cytogenetic Map1C4NCBI
Farsb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545311,176,432 - 11,240,780 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545311,176,481 - 11,237,243 (+)NCBIChiLan1.0ChiLan1.0
FARSB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B228,394,238 - 228,478,345 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B228,394,238 - 228,478,345 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B109,813,000 - 109,897,159 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
FARSB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13728,647,114 - 28,716,193 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3728,647,115 - 28,716,198 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3729,483,532 - 29,552,756 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03728,671,627 - 28,741,798 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13728,583,297 - 28,652,114 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03728,515,013 - 28,583,765 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03728,533,289 - 28,602,513 (-)NCBIUU_Cfam_GSD_1.0
Farsb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303178,181,689 - 178,261,741 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365694,524,525 - 4,604,539 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FARSB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.115124,472,236 - 124,555,042 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215137,963,814 - 137,984,032 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FARSB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110108,492,463 - 108,568,226 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10108,492,652 - 108,568,293 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604090,804,343 - 90,888,983 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Farsb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248232,559,756 - 2,627,606 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248232,559,757 - 2,627,606 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH134502  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2979,888,046 - 79,888,246 (+)MAPPERmRatBN7.2
Rnor_6.0984,324,651 - 84,324,850NCBIRnor6.0
Rnor_5.0984,083,536 - 84,083,735UniSTSRnor5.0
RGSC_v3.4977,806,768 - 77,806,967UniSTSRGSC3.4
Celera977,396,400 - 77,396,599UniSTS
RH 3.4 Map9728.7UniSTS
Cytogenetic Map9q33UniSTS
RH134923  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2979,947,723 - 79,947,903 (+)MAPPERmRatBN7.2
Rnor_6.0984,384,325 - 84,384,504NCBIRnor6.0
Rnor_5.0984,143,210 - 84,143,389UniSTSRnor5.0
RGSC_v3.4977,866,444 - 77,866,623UniSTSRGSC3.4
Celera977,456,042 - 77,456,221UniSTS
RH 3.4 Map9728.8UniSTS
Cytogenetic Map9q33UniSTS
RH139517  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2979,902,416 - 79,902,625 (+)MAPPERmRatBN7.2
Rnor_6.0984,339,018 - 84,339,226NCBIRnor6.0
Rnor_5.0984,097,903 - 84,098,111UniSTSRnor5.0
RGSC_v3.4977,821,137 - 77,821,345UniSTSRGSC3.4
Celera977,410,733 - 77,410,941UniSTS
RH 3.4 Map9728.5UniSTS
Cytogenetic Map9q33UniSTS
RH140352  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2979,902,516 - 79,902,651 (+)MAPPERmRatBN7.2
Rnor_6.0984,339,118 - 84,339,252NCBIRnor6.0
Rnor_5.0984,098,003 - 84,098,137UniSTSRnor5.0
RGSC_v3.4977,821,237 - 77,821,371UniSTSRGSC3.4
Celera977,410,833 - 77,410,967UniSTS
Cytogenetic Map9q33UniSTS
BE117296  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2979,897,056 - 79,897,253 (+)MAPPERmRatBN7.2
Rnor_6.0984,333,659 - 84,333,855NCBIRnor6.0
Rnor_5.0984,092,544 - 84,092,740UniSTSRnor5.0
RGSC_v3.4977,815,778 - 77,815,974UniSTSRGSC3.4
Celera977,405,374 - 77,405,570UniSTS
RH 3.4 Map9733.1UniSTS
Cytogenetic Map9q33UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
6903941Pur31Proteinuria QTL 310.036total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
4889852Pur26Proteinuria QTL 26150.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)97927151191616855Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:48
Count of miRNA genes:44
Interacting mature miRNAs:47
Transcripts:ENSRNOT00000019685
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 56 40 19 40 8 11 74 35 41 11 8
Low 1 1 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000019685   ⟹   ENSRNOP00000019685
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl979,887,842 - 79,947,036 (-)Ensembl
Rnor_6.0 Ensembl984,324,442 - 84,383,687 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094684   ⟹   ENSRNOP00000097472
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl979,887,874 - 79,947,045 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107975   ⟹   ENSRNOP00000097156
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl979,887,874 - 79,947,045 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118347   ⟹   ENSRNOP00000097872
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl979,904,604 - 79,947,042 (-)Ensembl
RefSeq Acc Id: NM_001004252   ⟹   NP_001004252
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2979,887,852 - 79,947,037 (-)NCBI
Rnor_6.0984,324,456 - 84,383,638 (-)NCBI
Rnor_5.0984,083,341 - 84,142,523 (-)NCBI
RGSC_v3.4977,806,573 - 77,865,757 (-)RGD
Celera977,396,205 - 77,455,355 (-)RGD
Sequence:
RefSeq Acc Id: XM_006245189   ⟹   XP_006245251
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2979,888,252 - 79,947,082 (-)NCBI
Rnor_6.0984,324,907 - 84,383,674 (-)NCBI
Rnor_5.0984,083,341 - 84,142,523 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001004252 (Get FASTA)   NCBI Sequence Viewer  
  XP_006245251 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79364 (Get FASTA)   NCBI Sequence Viewer  
  EDL75470 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001004252   ⟸   NM_001004252
- UniProtKB: Q68FT7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245251   ⟸   XM_006245189
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000019685   ⟸   ENSRNOT00000019685
RefSeq Acc Id: ENSRNOP00000097872   ⟸   ENSRNOT00000118347
RefSeq Acc Id: ENSRNOP00000097156   ⟸   ENSRNOT00000107975
RefSeq Acc Id: ENSRNOP00000097472   ⟸   ENSRNOT00000094684
Protein Domains
B5

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q68FT7-F1-model_v2 AlphaFold Q68FT7 1-589 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696788
Promoter ID:EPDNEW_R7312
Type:multiple initiation site
Name:Farsb_1
Description:phenylalanyl-tRNA synthetase, beta subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0984,383,646 - 84,383,706EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
9 84370726 84370727 T C snv SHRSP/Gcrc (RGD), BXH2/CubMcwi (2020), SHRSP/A3NCrl (2019), HXB10/IpcvMcwi (2019), HXB2/IpcvMcwi (2019), SHR/NHsd (RGD), SHR/OlalpcvMcwi (2019)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
9 84129611 84129612 T C snv SHR/NCrlPrin (KNAW), SHR/NHsd (KNAW), SHR/OlaIpcv (KNAW), DOB/Oda (KyushuU), SHRSP/Gcrc (KNAW), IS/Kyo (KyushuU), IS-Tlk/Kyo (KyushuU), SHR/OlaIpcvPrin (KNAW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
9 77852845 77852846 T C snv SHR/OlaIpcv (ICL), SHRSP/Gcrc (MDC), SHRSP/Gcrc (ICL), SHR/OlaIpcv (ICL), SHR/NHsd (ICL), SHR/OlaIpcv (KNAW)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
9 79934126 79934127 T C snv BXH2/CubMcwi (2020), HXB10/IpcvMcwi (2019), SHR/OlalpcvMcwi (2019), SHRSP/A3NCrl (2019), HXB2/IpcvMcwi (2019)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303210 AgrOrtholog
BioCyc Gene G2FUF-27024 BioCyc
BioCyc Pathway TRNA-CHARGING-PWY [tRNA charging] BioCyc
Ensembl Genes ENSRNOG00000014119 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000019685.4 UniProtKB/TrEMBL
  ENSRNOP00000097156.1 UniProtKB/TrEMBL
  ENSRNOP00000097472 ENTREZGENE
  ENSRNOP00000097472.1 UniProtKB/TrEMBL
  ENSRNOP00000097872 ENTREZGENE
  ENSRNOP00000097872.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019685.6 UniProtKB/TrEMBL
  ENSRNOT00000094684 ENTREZGENE
  ENSRNOT00000094684.1 UniProtKB/TrEMBL
  ENSRNOT00000107975.1 UniProtKB/TrEMBL
  ENSRNOT00000118347 ENTREZGENE
  ENSRNOT00000118347.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.930.10 UniProtKB/TrEMBL
  3.50.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7109296 IMAGE-MGC_LOAD
InterPro aa-tRNA-synth_II/BPL/LPL UniProtKB/TrEMBL
  B3/B4_tRNA-bd UniProtKB/TrEMBL
  DNA-bd_dom_put UniProtKB/TrEMBL
  IPR005147 UniProtKB/TrEMBL
  Phe-tRNA-ligase_IIc_bsu UniProtKB/TrEMBL
  Phe-tRNA-synth_IIc_bsu_arc UniProtKB/TrEMBL
  Phe-tRNA_synthase_B3/B4 UniProtKB/TrEMBL
  PheRS_beta_core UniProtKB/TrEMBL
  PhetRS_B1 UniProtKB/TrEMBL
KEGG Report rno:301544 UniProtKB/TrEMBL
MGC_CLONE MGC:94847 IMAGE-MGC_LOAD
NCBI Gene 301544 ENTREZGENE
PANTHER PTHR10947 UniProtKB/TrEMBL
Pfam B3_4 UniProtKB/TrEMBL
  PF03484 UniProtKB/TrEMBL
  PhetRS_B1 UniProtKB/TrEMBL
  tRNA_synthFbeta UniProtKB/TrEMBL
PhenoGen Farsb PhenoGen
PROSITE PS51483 UniProtKB/TrEMBL
SMART B3_4 UniProtKB/TrEMBL
  SM00874 UniProtKB/TrEMBL
Superfamily-SCOP Putativ_DNA_bind UniProtKB/TrEMBL
  SSF55681 UniProtKB/TrEMBL
TIGRFAMs pheT_arch UniProtKB/TrEMBL
UniProt A0A8I6ASF2_RAT UniProtKB/TrEMBL
  A0A8I6ATG0_RAT UniProtKB/TrEMBL
  F7FM91_RAT UniProtKB/TrEMBL
  Q68FT7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-07 Farsb  phenylalanyl-tRNA synthetase subunit beta  Farsb  phenylalanyl-tRNA synthetase, beta subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Farsb  phenylalanyl-tRNA synthetase, beta subunit  Farslb  phenylalanine-tRNA synthetase-like, beta subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Farslb  phenylalanine-tRNA synthetase-like, beta subunit      Symbol and Name status set to approved 1299863 APPROVED
2005-10-07 Farslb        Symbol and Name status set to provisional 70820 PROVISIONAL