Nol7 (nucleolar protein 7) - Rat Genome Database

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Gene: Nol7 (nucleolar protein 7) Rattus norvegicus
Analyze
Symbol: Nol7
Name: nucleolar protein 7
RGD ID: 1565934
Description: Predicted to be located in chromosome; mitochondrion; and nucleolus. Orthologous to human NOL7 (nucleolar protein 7); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC498727; Nol7-ps1; nucleolar protein 7, pseudogene 1; RGD1565934; similar to nucleolar protein 7, 27kDa
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21721,303,650 - 21,307,042 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1721,302,624 - 21,307,431 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1721,192,465 - 21,195,737 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01722,796,134 - 22,799,406 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01721,119,568 - 21,122,840 (-)NCBIRnor_WKY
Rnor_6.01724,016,939 - 24,020,231 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1724,015,982 - 24,020,261 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01725,966,367 - 25,969,809 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41727,127,979 - 27,132,484 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1721,001,063 - 21,004,415 (-)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromosome  (IEA,ISO)
mitochondrion  (IEA,ISO)
nucleolus  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:22658674  


Genomics

Comparative Map Data
Nol7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21721,303,650 - 21,307,042 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1721,302,624 - 21,307,431 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1721,192,465 - 21,195,737 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01722,796,134 - 22,799,406 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01721,119,568 - 21,122,840 (-)NCBIRnor_WKY
Rnor_6.01724,016,939 - 24,020,231 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1724,015,982 - 24,020,261 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01725,966,367 - 25,969,809 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41727,127,979 - 27,132,484 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1721,001,063 - 21,004,415 (-)NCBICelera
Cytogenetic Map17p12NCBI
NOL7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38613,615,335 - 13,632,470 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl613,615,335 - 13,632,739 (+)EnsemblGRCh38hg38GRCh38
GRCh37613,615,567 - 13,632,702 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36613,723,538 - 13,729,106 (+)NCBINCBI36Build 36hg18NCBI36
Build 34613,723,537 - 13,729,105NCBI
Celera614,855,054 - 14,860,622 (+)NCBICelera
Cytogenetic Map6p23NCBI
HuRef613,559,935 - 13,565,503 (+)NCBIHuRef
CHM1_1613,617,926 - 13,623,494 (+)NCBICHM1_1
T2T-CHM13v2.0613,488,892 - 13,506,009 (+)NCBIT2T-CHM13v2.0
Nol7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391343,551,852 - 43,556,334 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1343,551,866 - 43,560,573 (+)EnsemblGRCm39 Ensembl
GRCm381343,398,376 - 43,402,858 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1343,398,390 - 43,407,097 (+)EnsemblGRCm38mm10GRCm38
MGSCv371343,493,745 - 43,498,227 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361343,409,365 - 43,413,835 (+)NCBIMGSCv36mm8
Celera1344,476,966 - 44,481,446 (+)NCBICelera
Cytogenetic Map13A4NCBI
Nol7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554651,123,518 - 1,127,433 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554651,123,455 - 1,127,529 (-)NCBIChiLan1.0ChiLan1.0
NOL7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1613,828,474 - 13,837,472 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl613,831,493 - 13,836,712 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0613,460,225 - 13,466,230 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
NOL7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13513,058,894 - 13,063,367 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3513,017,397 - 13,063,022 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3513,008,242 - 13,012,362 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03513,157,389 - 13,161,539 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3513,115,780 - 13,179,805 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13512,982,835 - 12,986,958 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03513,034,346 - 13,038,501 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03514,359,355 - 14,363,470 (+)NCBIUU_Cfam_GSD_1.0
Nol7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494611,509,818 - 11,514,513 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936552217,340 - 222,420 (+)EnsemblSpeTri2.0
SpeTri2.0NW_004936552217,197 - 221,118 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOL7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl79,971,209 - 9,983,827 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.179,969,483 - 9,978,117 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NOL7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11758,528,431 - 58,532,563 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1758,528,500 - 58,532,533 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604413,665,438 - 13,679,174 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nol7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475612,673,398 - 12,677,173 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475612,673,328 - 12,677,223 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nol7
18 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:14
Count of miRNA genes:13
Interacting mature miRNAs:14
Transcripts:ENSRNOT00000024122
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122871563Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17211514921881669Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920136523653323Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920136523653323Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920136523653323Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)171398677321975515Rat
1331720Rf43Renal function QTL 432.881kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)171533061323017269Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat

Markers in Region
RH133329  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21721,304,079 - 21,304,340 (-)MAPPERmRatBN7.2
Rnor_6.01724,019,539 - 24,019,800NCBIRnor6.0
Rnor_5.01725,969,119 - 25,969,380UniSTSRnor5.0
Celera1721,001,506 - 21,001,766UniSTS
RH 3.4 Map17267.9UniSTS
Cytogenetic Map17p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000024122   ⟹   ENSRNOP00000024122
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1721,302,624 - 21,307,431 (-)Ensembl
Rnor_6.0 Ensembl1724,015,982 - 24,020,261 (+)Ensembl
RefSeq Acc Id: XM_006253849   ⟹   XP_006253911
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21721,303,650 - 21,307,042 (-)NCBI
Rnor_6.01724,016,939 - 24,020,231 (+)NCBI
Rnor_5.01725,966,367 - 25,969,809 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001387700 (Get FASTA)   NCBI Sequence Viewer  
  XP_006253911 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL98196 (Get FASTA)   NCBI Sequence Viewer  
  EDL98197 (Get FASTA)   NCBI Sequence Viewer  
  EDL98198 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_006253911   ⟸   XM_006253849
- Sequence:
RefSeq Acc Id: ENSRNOP00000024122   ⟸   ENSRNOT00000024122
Protein Domains
NUC129

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZAQ6-F1-model_v2 AlphaFold D3ZAQ6 1-297 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565934 AgrOrtholog
BioCyc Gene G2FUF-9800 BioCyc
Ensembl Genes ENSRNOG00000017904 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000024122 ENTREZGENE
  ENSRNOP00000024122.6 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024122 ENTREZGENE
  ENSRNOT00000024122.7 UniProtKB/TrEMBL
InterPro NOL7 UniProtKB/TrEMBL
  NUC129 UniProtKB/TrEMBL
NCBI Gene 498727 ENTREZGENE
PANTHER PTHR32337 UniProtKB/TrEMBL
Pfam NUC129 UniProtKB/TrEMBL
PhenoGen Nol7 PhenoGen
UniProt D3ZAQ6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-05 Nol7  nucleolar protein 7  Nol7-ps1  nucleolar protein 7, pseudogene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-06-08 Nol7-ps1  nucleolar protein 7, pseudogene 1  Nol7  nucleolar protein 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Nol7  nucleolar protein 7  RGD1565934_predicted  similar to nucleolar protein 7, 27kDa (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1565934_predicted  similar to nucleolar protein 7, 27kDa (predicted)  LOC498727  similar to nucleolar protein 7, 27kDa  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498727  similar to nucleolar protein 7, 27kDa      Symbol and Name status set to provisional 70820 PROVISIONAL