Prep (prolyl endopeptidase) - Rat Genome Database

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Gene: Prep (prolyl endopeptidase) Rattus norvegicus
Analyze
Symbol: Prep
Name: prolyl endopeptidase
RGD ID: 620841
Description: Enables endopeptidase activity and peptide binding activity. Involved in protein catabolic process. Located in cytosol. Biomarker of mental depression. Orthologous to human PREP (prolyl endopeptidase); INTERACTS WITH 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: PE; post-proline cleaving enzyme; rPop
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22048,556,211 - 48,653,165 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2048,556,280 - 48,654,466 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2050,300,058 - 50,395,795 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02049,949,970 - 50,045,703 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02050,634,121 - 50,729,857 (+)NCBIRnor_WKY
Rnor_6.02050,172,618 - 50,269,992 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2050,172,618 - 50,269,992 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02051,789,200 - 51,885,778 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42049,024,917 - 49,144,670 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12049,053,613 - 49,173,367 (+)NCBI
Celera2051,366,123 - 51,463,044 (-)NCBICelera
Cytogenetic Map20q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO)
cytosol  (IBA,IDA,IEA,ISO)
nucleus  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Distribution of prolyl endopeptidase activities in rat and human brain. Irazusta J, etal., Neurochem Int 2002 Apr;40(4):337-45.
4. Activities of prolyl endopeptidase and dipeptidyl peptidase IV in brain structures of rats with dopamine deficiency-dependent MPTP-induced depressive syndrome. Krupina NA, etal., Bull Exp Biol Med. 2006 Nov;142(5):554-6.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9538240   PMID:14986307   PMID:15037553   PMID:15985312   PMID:17401647   PMID:19041368   PMID:19946888   PMID:20304043   PMID:21160163   PMID:21820035   PMID:24288747   PMID:30380361  
PMID:30627904   PMID:34225593  


Genomics

Comparative Map Data
Prep
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22048,556,211 - 48,653,165 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2048,556,280 - 48,654,466 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2050,300,058 - 50,395,795 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02049,949,970 - 50,045,703 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02050,634,121 - 50,729,857 (+)NCBIRnor_WKY
Rnor_6.02050,172,618 - 50,269,992 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2050,172,618 - 50,269,992 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02051,789,200 - 51,885,778 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42049,024,917 - 49,144,670 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12049,053,613 - 49,173,367 (+)NCBI
Celera2051,366,123 - 51,463,044 (-)NCBICelera
Cytogenetic Map20q13NCBI
PREP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386105,273,218 - 105,403,082 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl6105,273,218 - 105,454,062 (-)EnsemblGRCh38hg38GRCh38
GRCh376105,721,093 - 105,850,957 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366105,832,199 - 105,957,662 (-)NCBINCBI36Build 36hg18NCBI36
Build 346105,832,198 - 105,957,662NCBI
Celera6106,347,577 - 106,473,093 (-)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6103,168,797 - 103,294,318 (-)NCBIHuRef
CHM1_16105,987,432 - 106,112,999 (-)NCBICHM1_1
T2T-CHM13v2.06106,448,949 - 106,578,910 (-)NCBIT2T-CHM13v2.0
Prep
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391044,943,312 - 45,038,847 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1044,943,299 - 45,043,294 (+)EnsemblGRCm39 Ensembl
GRCm381045,067,216 - 45,162,751 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1045,067,203 - 45,167,198 (+)EnsemblGRCm38mm10GRCm38
MGSCv371044,787,020 - 44,878,801 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361044,755,629 - 44,847,410 (+)NCBIMGSCv36mm8
Celera1045,941,173 - 46,032,935 (+)NCBICelera
Cytogenetic Map10B2NCBI
cM Map1023.27NCBI
Prep
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541130,698,112 - 30,835,923 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541130,698,112 - 30,797,096 (-)NCBIChiLan1.0ChiLan1.0
PREP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16106,965,275 - 107,093,091 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6106,965,275 - 107,091,278 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06103,091,315 - 103,219,335 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PREP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11262,709,158 - 62,821,247 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1262,709,434 - 62,829,084 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1262,497,580 - 62,615,079 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01263,560,860 - 63,678,389 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1263,560,878 - 63,680,592 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11262,915,128 - 63,032,788 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01262,756,480 - 62,874,410 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01263,035,919 - 63,153,927 (-)NCBIUU_Cfam_GSD_1.0
Prep
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494697,669,412 - 97,787,348 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365641,944,245 - 2,062,178 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PREP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl171,496,306 - 71,636,747 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1171,496,299 - 72,027,308 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2180,817,291 - 80,892,385 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PREP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11368,406,298 - 68,536,166 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1368,406,452 - 68,536,234 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604040,749,136 - 40,882,911 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prep
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624952502,274 - 620,943 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624952504,943 - 620,968 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH124895  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22048,652,828 - 48,653,049 (+)MAPPERmRatBN7.2
Rnor_6.02050,269,656 - 50,269,876NCBIRnor6.0
Rnor_5.02051,885,442 - 51,885,662UniSTSRnor5.0
RGSC_v3.42049,144,334 - 49,144,554UniSTSRGSC3.4
Celera2051,366,238 - 51,366,459UniSTS
Cytogenetic Map20q13UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat
2317880Alcrsp25Alcohol response QTL 252.3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)201769755054435887Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)201919072154435887Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202510672254435887Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202510672254435887Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202510672254435887Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202520973454435887Rat
1598869Memor6Memory QTL 63.1exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)202924438854435887Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 36 55 41 19 41 8 11 74 35 35 11 8
Low 7 2 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000076640
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2048,560,599 - 48,654,466 (+)Ensembl
Rnor_6.0 Ensembl2050,172,618 - 50,269,992 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091456   ⟹   ENSRNOP00000071906
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2048,556,280 - 48,654,466 (+)Ensembl
Rnor_6.0 Ensembl2050,172,618 - 50,269,992 (+)Ensembl
RefSeq Acc Id: NM_031324   ⟹   NP_112614
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22048,556,211 - 48,653,165 (+)NCBI
Rnor_6.02050,172,618 - 50,269,992 (+)NCBI
Rnor_5.02051,789,200 - 51,885,778 (+)NCBI
RGSC_v3.42049,024,917 - 49,144,670 (+)RGD
Celera2051,366,123 - 51,463,044 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_112614 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAA25544 (Get FASTA)   NCBI Sequence Viewer  
  EDL99674 (Get FASTA)   NCBI Sequence Viewer  
  O70196 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_112614   ⟸   NM_031324
- Sequence:
RefSeq Acc Id: ENSRNOP00000071906   ⟸   ENSRNOT00000091456
Protein Domains
Peptidase_S9   Peptidase_S9_N

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O70196-F1-model_v2 AlphaFold O70196 1-710 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701693
Promoter ID:EPDNEW_R12208
Type:initiation region
Name:Prep_1
Description:prolyl endopeptidase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02050,172,626 - 50,172,686EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620841 AgrOrtholog
BioCyc Gene G2FUF-3271 BioCyc
Ensembl Genes ENSRNOG00000051061 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000071906 ENTREZGENE
  ENSRNOP00000071906.2 UniProtKB/TrEMBL
  ENSRNOP00000087163.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000076640.2 UniProtKB/TrEMBL
  ENSRNOT00000091456 ENTREZGENE
  ENSRNOT00000091456.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_S9_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_S9A_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S9A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83471 UniProtKB/Swiss-Prot
NCBI Gene 83471 ENTREZGENE
Pfam Peptidase_S9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S9_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Prep PhenoGen
PRINTS PROLIGOPTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PRO_ENDOPEP_SER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K1M8_RAT UniProtKB/TrEMBL
  A0A8I6A5B9_RAT UniProtKB/TrEMBL
  O70196 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Prep  prolyl endopeptidase      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Prep  prolyl endopeptidase      Symbol and Name status set to provisional 70820 PROVISIONAL