Gene: Snta1 (syntrophin, alpha 1) Rattus norvegicus
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Symbol: Snta1
Name: syntrophin, alpha 1
Description: ENCODES a protein that exhibits PDZ domain binding; ATPase binding (ortholog); ion channel binding (ortholog); INVOLVED IN negative regulation of peptidyl-cysteine S-nitrosylation (ortholog); neuromuscular junction development (ortholog); regulation of heart rate (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH status epilepticus; arrhythmogenic right ventricular cardiomyopathy (ortholog); Becker muscular dystrophy (ortholog); FOUND IN neuromuscular junction; sarcolemma; postsynaptic membrane (ortholog); INTERACTS WITH (+)-pilocarpine; 3-chloropropane-1,2-diol; acrylamide
AGR Description: Exhibits PDZ domain binding activity; predicted to contribute to sodium channel regulator activity; predicted to be involved in several processes, including negative regulation of peptidyl-cysteine S-nitrosylation, regulation of blood circulation, and regulation of ion transmembrane transport; localizes to the neuromuscular junction and sarcolemma; biomarker of status epilepticus; orthologous to human SNTA1 (syntrophin alpha 1).
Merged Description: Exhibits PDZ domain binding activity; predicted to contribute to sodium channel regulator activity; predicted to be involved in several processes, including negative regulation of peptidyl-cysteine S-nitrosylation, regulation of blood circulation, and regulation of ion transmembrane transport; localizes to the neuromuscular junction and sarcolemma; biomarker of status epilepticus; orthologous to human SNTA1 (syntrophin alpha 1); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH (+)-pilocarpine; 3-chloropropane-1,2-diol; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha-1-syntrophin; LOC362242; syntrophin, acidic 1
Orthologs:
Homo sapiens (human) : SNTA1 (syntrophin alpha 1)  HGNC  Alliance
Mus musculus (house mouse) : Snta1 (syntrophin, acidic 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snta1 (syntrophin alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SNTA1 (syntrophin alpha 1)
Canis lupus familiaris (dog) : SNTA1 (syntrophin alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snta1 (syntrophin alpha 1)
Sus scrofa (pig) : SNTA1 (syntrophin alpha 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03149,874,023 - 149,905,980 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03156,245,190 - 156,278,486 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43144,843,678 - 144,874,238 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13144,749,301 - 144,779,860 (-)NCBI
Celera3141,611,616 - 141,641,783 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Snta1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307068
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.