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Gene: Las1l (LAS1-like, ribosome biogenesis factor) Rattus norvegicus
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Symbol: Las1l
Name: LAS1-like, ribosome biogenesis factor
RGD ID: 1565755
Description: Predicted to have endonuclease activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to localize to MLL1 complex and preribosome, large subunit precursor. Human ortholog(s) of this gene implicated in Wilson-Turner syndrome. Orthologous to human LAS1L (LAS1 like ribosome biogenesis factor); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LAS1-like; LAS1-like (S. cerevisiae); LOC296865; MGC189399; RGD1565755; ribosomal biogenesis protein LAS1L
Orthologs:
Homo sapiens (human) : LAS1L (LAS1 like ribosome biogenesis factor)  HGNC  Alliance
Mus musculus (house mouse) : Las1l (LAS1-like (S. cerevisiae))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Las1l (LAS1 like ribosome biogenesis factor)
Pan paniscus (bonobo/pygmy chimpanzee) : LAS1L (LAS1 like ribosome biogenesis factor)
Canis lupus familiaris (dog) : LAS1L (LAS1 like ribosome biogenesis factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Las1l (LAS1 like ribosome biogenesis factor)
Sus scrofa (pig) : LAS1L (LAS1 like ribosome biogenesis factor)
Chlorocebus sabaeus (African green monkey) : LAS1L (LAS1 like ribosome biogenesis factor)
Heterocephalus glaber (naked mole-rat) : Las1l (LAS1 like ribosome biogenesis factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X65,081,591 - 65,102,344 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX65,081,591 - 65,102,380 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X65,923,644 - 65,944,397 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X83,568,652 - 83,590,289 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX61,266,251 - 61,287,857 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Las1l
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1565755
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.