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Gene: Las1l (LAS1-like, ribosome biogenesis factor) Rattus norvegicus
Symbol: Las1l
Name: LAS1-like, ribosome biogenesis factor
RGD ID: 1565755
Description: Predicted to have endonuclease activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to localize to MLL1 complex and preribosome, large subunit precursor. Human ortholog(s) of this gene implicated in Wilson-Turner syndrome. Orthologous to human LAS1L (LAS1 like ribosome biogenesis factor); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LAS1-like; LAS1-like (S. cerevisiae); LOC296865; MGC189399; RGD1565755; ribosomal biogenesis protein LAS1L
Homo sapiens (human) : LAS1L (LAS1 like ribosome biogenesis factor)  HGNC  Alliance
Mus musculus (house mouse) : Las1l (LAS1-like (S. cerevisiae))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Las1l (LAS1 like ribosome biogenesis factor)
Pan paniscus (bonobo/pygmy chimpanzee) : LAS1L (LAS1 like ribosome biogenesis factor)
Canis lupus familiaris (dog) : LAS1L (LAS1 like ribosome biogenesis factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Las1l (LAS1 like ribosome biogenesis factor)
Sus scrofa (pig) : LAS1L (LAS1 like ribosome biogenesis factor)
Chlorocebus sabaeus (African green monkey) : LAS1L (LAS1 like ribosome biogenesis factor)
Heterocephalus glaber (naked mole-rat) : Las1l (LAS1 like ribosome biogenesis factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X65,081,591 - 65,102,344 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX65,081,591 - 65,102,380 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X65,923,644 - 65,944,397 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X83,568,652 - 83,590,289 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX61,266,251 - 61,287,857 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Las1l
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1565755
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.