Nfs1 (NFS1 cysteine desulfurase) - Rat Genome Database

Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Nfs1 (NFS1 cysteine desulfurase) Rattus norvegicus
Analyze
Symbol: Nfs1
Name: NFS1 cysteine desulfurase
RGD ID: 620912
Description: Predicted to enable cysteine desulfurase activity and protein homodimerization activity. Predicted to be involved in iron incorporation into metallo-sulfur cluster. Predicted to be located in mitochondrial matrix and nucleoplasm. Predicted to be active in cytosol; mitochondrion; and nucleus. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency. Orthologous to human NFS1 (NFS1 cysteine desulfurase); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; thiamine metabolic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cysteine desulfurase; cysteine desulfurase, mitochondrial; cysteine desulfurase, mitochondrial-like; LOC100911034; MGC124952; NFS1 nitrogen fixation 1 homolog; NFS1 nitrogen fixation 1 homolog (S. cerevisiae); Nifs; nitrogen fixation gene 1; nitrogen fixation gene 1 (S. cerevisiae)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23144,637,309 - 144,659,660 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl3144,637,309 - 144,659,666 (-)Ensembl
Rnor_6.03151,665,813 - 151,688,151 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3152,200,936 - 152,222,647 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl3151,665,814 - 151,688,149 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03158,030,431 - 158,052,775 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43146,528,820 - 146,551,156 (-)NCBIRGSC3.4rn4RGSC3.4
Celera3143,359,073 - 143,381,415 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,IEA,ISO)
mitochondrial matrix  (IEA,ISO)
mitochondrion  (IBA,ISO,ISS)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:9738949   PMID:14651853   PMID:16527810   PMID:16787928   PMID:16847322   PMID:18614015   PMID:20873749   PMID:26702583   PMID:30053369  


Genomics

Comparative Map Data
Nfs1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23144,637,309 - 144,659,660 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl3144,637,309 - 144,659,666 (-)Ensembl
Rnor_6.03151,665,813 - 151,688,151 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3152,200,936 - 152,222,647 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl3151,665,814 - 151,688,149 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03158,030,431 - 158,052,775 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43146,528,820 - 146,551,156 (-)NCBIRGSC3.4rn4RGSC3.4
Celera3143,359,073 - 143,381,415 (-)NCBICelera
Cytogenetic Map3q42NCBI
NFS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382035,668,052 - 35,699,352 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2035,668,052 - 35,699,355 (-)EnsemblGRCh38hg38GRCh38
GRCh372034,255,974 - 34,287,274 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362033,720,025 - 33,750,688 (-)NCBINCBI36hg18NCBI36
Build 342033,745,916 - 33,750,688NCBI
Celera2031,004,905 - 31,035,569 (-)NCBI
Cytogenetic Map20q11.22NCBI
HuRef2031,034,024 - 31,064,670 (-)NCBIHuRef
CHM1_12034,158,261 - 34,189,218 (-)NCBICHM1_1
T2T-CHM13v2.02037,389,027 - 37,420,327 (-)NCBI
Nfs1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392155,965,557 - 155,986,134 (-)NCBIGRCm39mm39
GRCm39 Ensembl2155,965,559 - 155,986,106 (-)Ensembl
GRCm382156,123,637 - 156,144,202 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2156,123,639 - 156,144,186 (-)EnsemblGRCm38mm10GRCm38
MGSCv372155,949,373 - 155,969,922 (-)NCBIGRCm37mm9NCBIm37
MGSCv362155,815,090 - 155,835,626 (-)NCBImm8
Celera2162,059,133 - 162,079,762 (-)NCBICelera
Cytogenetic Map2H1NCBI
Nfs1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542225,760,099 - 25,785,108 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542225,759,988 - 25,785,560 (+)NCBIChiLan1.0ChiLan1.0
NFS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12033,116,018 - 33,147,749 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v02031,994,509 - 32,026,776 (-)NCBIMhudiblu_PPA_v0panPan3
NFS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12424,593,348 - 24,614,938 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2424,594,264 - 24,614,902 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2424,238,426 - 24,259,999 (-)NCBI
ROS_Cfam_1.02425,285,895 - 25,307,493 (-)NCBI
ROS_Cfam_1.0 Ensembl2425,285,893 - 25,307,884 (-)Ensembl
UMICH_Zoey_3.12424,572,224 - 24,593,783 (-)NCBI
UNSW_CanFamBas_1.02424,667,259 - 24,688,864 (-)NCBI
UU_Cfam_GSD_1.02425,106,694 - 25,128,280 (-)NCBI
Nfs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640173,590,462 - 173,613,116 (-)NCBI
SpeTri2.0NW_0049365615,136,692 - 5,158,266 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1739,000,642 - 39,029,186 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11739,000,659 - 39,029,179 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21744,351,262 - 44,379,781 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NFS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1256,592,304 - 56,617,510 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl256,592,308 - 56,617,469 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660872,935,798 - 2,960,540 (-)NCBIVero_WHO_p1.0
Nfs1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248423,736,411 - 3,774,014 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248423,736,352 - 3,774,456 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D3Rat237  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23144,655,696 - 144,655,803 (+)MAPPERmRatBN7.2
Rnor_6.03152,218,714 - 152,218,820NCBIRnor6.0
Rnor_6.03151,684,201 - 151,684,307NCBIRnor6.0
Rnor_5.03159,471,961 - 159,472,067UniSTSRnor5.0
Rnor_5.03158,048,819 - 158,048,925UniSTSRnor5.0
RGSC_v3.43146,547,207 - 146,547,314RGDRGSC3.4
RGSC_v3.43146,547,208 - 146,547,314UniSTSRGSC3.4
RGSC_v3.13146,453,116 - 146,453,223RGD
Celera3143,377,467 - 143,377,573UniSTS
FHH x ACI Map385.78UniSTS
FHH x ACI Map385.78RGD
Cytogenetic Map3q42UniSTS
RH128176  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23144,637,527 - 144,637,725 (+)MAPPERmRatBN7.2
Rnor_6.03152,200,541 - 152,200,738NCBIRnor6.0
Rnor_6.03151,666,032 - 151,666,229NCBIRnor6.0
Rnor_5.03159,490,043 - 159,490,240UniSTSRnor5.0
Rnor_5.03158,030,650 - 158,030,847UniSTSRnor5.0
RGSC_v3.43146,529,039 - 146,529,236UniSTSRGSC3.4
Celera3143,359,292 - 143,359,489UniSTS
RH 3.4 Map31330.1UniSTS
Cytogenetic Map3q42UniSTS
RH139369  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23144,661,193 - 144,661,261 (+)MAPPERmRatBN7.2
Rnor_6.03152,224,210 - 152,224,277NCBIRnor6.0
Rnor_6.03151,689,697 - 151,689,764NCBIRnor6.0
Rnor_5.03159,466,504 - 159,466,571UniSTSRnor5.0
Rnor_5.03158,054,315 - 158,054,382UniSTSRnor5.0
RGSC_v3.43146,552,704 - 146,552,771UniSTSRGSC3.4
Celera3143,382,963 - 143,383,030UniSTS
RH 3.4 Map31328.6UniSTS
Cytogenetic Map3q42UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1581568Rf53Renal function QTL 53total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1581546Pur13Proteinuria QTL 132.930.0335total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3140069424146976080Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141339236155617360Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:142
Count of miRNA genes:90
Interacting mature miRNAs:108
Transcripts:ENSRNOT00000026820, ENSRNOT00000072945
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 36 50 41 4 41 3 6 57 35 29 9 3
Low 7 7 15 5 5 17 12 2 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000026820   ⟹   ENSRNOP00000026820
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3152,200,936 - 152,222,647 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000072945   ⟹   ENSRNOP00000066678
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3144,637,309 - 144,659,666 (-)Ensembl
Rnor_6.0 Ensembl3151,665,814 - 151,688,149 (-)Ensembl
RefSeq Acc Id: NM_053462   ⟹   NP_445914
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23144,637,309 - 144,659,645 (-)NCBI
Rnor_6.03151,665,813 - 151,688,149 (-)NCBI
Rnor_5.03158,030,431 - 158,052,775 (-)NCBI
RGSC_v3.43146,528,820 - 146,551,156 (-)RGD
Celera3143,359,073 - 143,381,415 (-)RGD
Sequence:
RefSeq Acc Id: XM_006235451   ⟹   XP_006235513
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23144,637,309 - 144,659,660 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_445914   ⟸   NM_053462
- UniProtKB: Q3MHT2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000066678   ⟸   ENSRNOT00000072945
RefSeq Acc Id: ENSRNOP00000026820   ⟸   ENSRNOT00000026820
RefSeq Acc Id: XP_006235513   ⟸   XM_006235451
- Peptide Label: isoform X1
- Sequence:
Protein Domains
Aminotran_5

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99P39-F1-model_v2 AlphaFold Q99P39 1-451 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692594
Promoter ID:EPDNEW_R3119
Type:initiation region
Name:Nfs1_2
Description:NFS1 cysteine desulfurase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3121  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03151,688,168 - 151,688,228EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620912 AgrOrtholog
BioCyc Gene G2FUF-47104 BioCyc
BioCyc Pathway PWY-7250 [[2Fe-2S] iron-sulfur cluster biosynthesis] BioCyc
Ensembl Genes ENSRNOG00000019736 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000045686 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000026820 UniProtKB/TrEMBL
  ENSRNOP00000066678 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026820 UniProtKB/TrEMBL
  ENSRNOT00000072945 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.640.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1150.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7104648 IMAGE-MGC_LOAD
  IMAGE:7189705 IMAGE-MGC_LOAD
  IMAGE:7189856 IMAGE-MGC_LOAD
InterPro Aminotrans_V_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aminotrans_V_PyrdxlP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cys_deSase_IscS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cysteine_dSase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_dom1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_major UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:84594 UniProtKB/TrEMBL, UniProtKB/TrEMBL
MGC_CLONE MGC:105371 IMAGE-MGC_LOAD
  MGC:124952 IMAGE-MGC_LOAD
  MGC:91577 IMAGE-MGC_LOAD
NCBI Gene 84594 ENTREZGENE
PANTHER PTHR11601:SF34 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Aminotran_5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nfs1 PhenoGen
PIRSF NifS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE AA_TRANSFER_CLASS_5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53383 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs IscS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt NFS1_RAT UniProtKB/Swiss-Prot
  Q3MHT2 ENTREZGENE, UniProtKB/TrEMBL
  Q5FWU2_RAT UniProtKB/TrEMBL
  Q99P39 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-21 Nfs1  NFS1 cysteine desulfurase  LOC100911034  cysteine desulfurase, mitochondrial-like  Data Merged 737654 APPROVED
2013-08-14 Nfs1  NFS1 cysteine desulfurase  Nfs1  NFS1 nitrogen fixation 1 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911034  cysteine desulfurase, mitochondrial-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-09-24 Nfs1  NFS1 nitrogen fixation 1 homolog (S. cerevisiae)  Nfs1  nitrogen fixation gene 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Nfs1  nitrogen fixation gene 1 (S. cerevisiae)  Nifs  cysteine desulfurase  Symbol and Name updated 1299863 APPROVED
2002-08-07 Nifs  cysteine desulfurase      Symbol and Name status set to provisional 70820 PROVISIONAL