 Gene Ontology Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cellular Component
Molecular Function
Molecular Pathway Annotations |
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Analyze GeneStrainQTL List |
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Gene Annotator (Annotation Comparison) |
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Cellular Component
Molecular Function
Molecular Pathway AnnotationsGene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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Molecular Pathway AnnotationsReferences - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | Maio N and Rouault TA, Biochim Biophys Acta. 2015 Jun;1853(6):1493-512. doi: 10.1016/j.bbamcr.2014.09.009. Epub 2014 Sep 19. |
| 3. | MGD data from the GO Consortium |
| 4. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 5. | Pipeline to import KEGG annotations from KEGG into RGD |
| 6. | RGD automated data pipeline |
| 7. | RGD automated import pipeline for gene-chemical interactions |
| 8. | RGD, Sept. 2003 |
| 9. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
References - uncuratedGenomics
Comparative Map Data| Nfs1 (Rattus norvegicus - Norway rat) |
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| NFS1 (Homo sapiens - human) |
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| Nfs1 (Mus musculus - house mouse) |
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| Nfs1 (Chinchilla lanigera - long-tailed chinchilla) |
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| NFS1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| NFS1 (Canis lupus familiaris - dog) |
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| Nfs1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| NFS1 (Sus scrofa - pig) |
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| NFS1 (Chlorocebus sabaeus - African green monkey) |
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| Nfs1 (Heterocephalus glaber - naked mole-rat) |
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Position Markers| D3Rat237 |
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| RH128176 |
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| RH139369 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 3 | 36 | 50 | 41 | 4 | 41 | 3 | 6 | 57 | 35 | 29 | 9 | 3 |
| Low | 7 | 7 | 15 | 5 | 5 | 17 | 12 | 2 | 5 | ||||
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_053462 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_006235365 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AC118414 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AF336041 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC072482 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC089205 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC104699 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH474050 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000026820 ⟹ ENSRNOP00000026820 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | ENSRNOT00000072945 ⟹ ENSRNOP00000066678 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_053462 ⟹ NP_445914 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
TTGCAAGCGACGCAGATGGTGGGCTCTGTTGCTGGGAACATGCTGCTGCGAGCCGCTTGGAGGChide sequence |
| RefSeq Acc Id: | XM_006235365 ⟹ XP_006235427 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
ACTTGCAAGCGACGCAGATGGTGGGCTCTGTTGCTGGGAACATGCTGCTGCGAGCCGCTTGGAGhide sequence |
Protein Sequences| Protein RefSeqs | NP_445914 | (Get FASTA) | NCBI Sequence Viewer |
| XP_006235427 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAH89205 | (Get FASTA) | NCBI Sequence Viewer |
| AAI04700 | (Get FASTA) | NCBI Sequence Viewer | |
| AAK12337 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL85865 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL85866 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL85867 | (Get FASTA) | NCBI Sequence Viewer | |
| Q99P39 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_445914 ⟸ NM_053462 |
| - UniProtKB: | Q3MHT2 (UniProtKB/TrEMBL) |
| - Sequence: |
MVGSVAGNMLLRAAWRRASLAATSVALRRSSVPTRGLRLRVVDHAPHSAVPSEAEAVLRPLYMDhide sequence |
| RefSeq Acc Id: | XP_006235427 ⟸ XM_006235365 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MVGSVAGNMLLRAAWRRASLAATSVALRRSSVPTRGLRLRVVDHAPHSAVPSEAEAVLRPLYMDhide sequence |
| RefSeq Acc Id: | ENSRNOP00000066678 ⟸ ENSRNOT00000072945 |
| RefSeq Acc Id: | ENSRNOP00000026820 ⟸ ENSRNOT00000026820 |
Protein Domains
Aminotran_5
TranscriptomePromoters| RGD ID: | 13692594 | ||||||||
| Promoter ID: | EPDNEW_R3119 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Nfs1_2 | ||||||||
| Description: | NFS1 cysteine desulfurase | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Alternative Promoters: | null; see alsoEPDNEW_R3121 | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:620912 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000019736 | Ensembl, UniProtKB/TrEMBL |
| ENSRNOG00000045686 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL | |
| Ensembl Protein | ENSRNOP00000026820 | UniProtKB/TrEMBL |
| ENSRNOP00000066678 | ENTREZGENE, UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000026820 | UniProtKB/TrEMBL |
| ENSRNOT00000072945 | ENTREZGENE, UniProtKB/TrEMBL | |
| Gene3D-CATH | 3.40.640.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| 3.90.1150.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| IMAGE_CLONE | IMAGE:7104648 | IMAGE-MGC_LOAD |
| IMAGE:7189705 | IMAGE-MGC_LOAD | |
| IMAGE:7189856 | IMAGE-MGC_LOAD | |
| InterPro | Aminotrans_V_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| Aminotrans_V_PyrdxlP_BS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| Cys_deSase_IscS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| Cysteine_dSase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| PyrdxlP-dep_Trfase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| PyrdxlP-dep_Trfase_dom1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| PyrdxlP-dep_Trfase_major | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| KEGG Report | rno:100911034 | UniProtKB/TrEMBL, UniProtKB/TrEMBL |
| rno:84594 | UniProtKB/TrEMBL, UniProtKB/TrEMBL | |
| MGC_CLONE | MGC:105371 | IMAGE-MGC_LOAD |
| MGC:124952 | IMAGE-MGC_LOAD | |
| MGC:91577 | IMAGE-MGC_LOAD | |
| NCBI Gene | 84594 | ENTREZGENE |
| PANTHER | PTHR11601:SF34 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| Pfam | Aminotran_5 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| PhenoGen | Nfs1 | PhenoGen |
| PIRSF | NifS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| PROSITE | AA_TRANSFER_CLASS_5 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| Superfamily-SCOP | SSF53383 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| TIGRFAMs | IscS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| UniGene | Rn.3151 | ENTREZGENE |
| UniProt | NFS1_RAT | UniProtKB/Swiss-Prot |
| Q3MHT2 | ENTREZGENE, UniProtKB/TrEMBL | |
| Q5FWU2_RAT | UniProtKB/TrEMBL | |
| Q99P39 | ENTREZGENE |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2015-07-21 | Nfs1 | NFS1 cysteine desulfurase | LOC100911034 | cysteine desulfurase, mitochondrial-like | Data Merged | 737654 | APPROVED |
| 2013-08-14 | Nfs1 | NFS1 cysteine desulfurase | Nfs1 | NFS1 nitrogen fixation 1 homolog (S. cerevisiae) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2012-07-05 | LOC100911034 | cysteine desulfurase, mitochondrial-like | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
| 2008-09-24 | Nfs1 | NFS1 nitrogen fixation 1 homolog (S. cerevisiae) | Nfs1 | nitrogen fixation gene 1 (S. cerevisiae) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2005-01-20 | Nfs1 | nitrogen fixation gene 1 (S. cerevisiae) | Nifs | cysteine desulfurase | Symbol and Name updated | 1299863 | APPROVED |
| 2002-08-07 | Nifs | cysteine desulfurase | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
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| More on Nfs1 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 620912 |
| Created: | 2002-08-06 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-08-20 |
| Status: | ACTIVE |
