diquat - Ontology Report - Rat Genome Database

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

{{ watchLinkText }}

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	diquat	go back to main search page
Accession:	CHEBI:64163	browse the term
Definition:	The organic cation formed formally by addition of an ethylene bridge between the nitrogen atoms of 2,2'-bipyridine. Most often available as the dibromide.
Synonyms:	exact_synonym:	6,7-dihydrodipyrido[1,2-a:2',1'-c]pyrazinediium
	related_synonym:	1,1'-Ethylene-2,2'-bipyridyldylium ion; 1,1'-Ethylene-2,2'-bipyridylium ion; 9,10-Dihydro-8a,10a-diazoniaphenanthrene; Diquat dication; Formula=C12H12N2; InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2; InChIKey=SYJFEGQWDCRVNX-UHFFFAOYSA-N; SMILES=C1C[n+]2ccccc2-c2cccc[n+]12
	xref:	CAS:2764-72-9; KEGG:C18577
	xref_mesh:	MESH:D004178
	xref:	PPDB:1541; Reaxys:3670526; Wikipedia:Diquat

show annotations for term's descendants Sort by:
Rat (1182) Mouse (1254) Human (1185) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (20) Green Monkey (0) Naked Mole-rat (0) All
Genes (1182)

diquat

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

decreases expression

Diquat results in decreased expression of PZP mRNA

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

G

alpha 1,4-galactosyltransferase

increases expression

Diquat results in increased expression of A4GALT mRNA

NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071

G

ATP-binding cassette, sub-family B member 1B

increases expression

Diquat results in increased expression of ABCB1B mRNA

NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199

G

ATP binding cassette subfamily C member 2

increases expression

Diquat results in increased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 4

increases expression

Diquat results in increased expression of ABCC4 mRNA; Diquat results in increased expression of ABCC4 protein

NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283

G

abhydrolase domain containing 14A

decreases expression

Diquat results in decreased expression of ABHD14A mRNA

NCBI chr 8:107,079,139...107,089,004
Ensembl chr 8:107,079,144...107,086,985

G

abhydrolase domain containing 15

increases expression

Diquat results in increased expression of ABHD15 mRNA

NCBI chr10:62,363,209...62,368,600
Ensembl chr10:62,363,209...62,368,600

G

abhydrolase domain containing 4, N-acyl phospholipase B

increases expression

Diquat results in increased expression of ABHD4 protein

NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966

G

ABI family member 3 binding protein

decreases expression

Diquat results in decreased expression of ABI3BP mRNA

NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929

G

acetyl-Coenzyme A acyltransferase 1B

increases expression

Diquat results in increased expression of ACAA1B mRNA

NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825

G

acetyl-CoA acyltransferase 2

increases expression

Diquat results in increased expression of ACAA2 mRNA

NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249

G

acyl-CoA thioesterase 1

increases expression

Diquat results in increased expression of ACOT1 mRNA

NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163

G

acyl-CoA thioesterase 2

increases expression

Diquat results in increased expression of ACOT2 mRNA

NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245

G

acyl-CoA thioesterase 3

increases expression

Diquat results in increased expression of ACOT3 mRNA

NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,682,596...103,688,427
Ensembl chr 6:103,682,596...103,688,427

G

acyl-CoA thioesterase 8

increases expression

Diquat results in increased expression of ACOT8 mRNA

NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851

G

acyl-CoA oxidase 1

increases expression

Diquat results in increased expression of ACOX1 mRNA

NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232

G

acyl-CoA oxidase 2

increases expression

Diquat results in increased expression of ACOX2 mRNA

NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160

G

acid phosphatase 3

decreases expression

Diquat results in decreased expression of ACP3 mRNA

NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236

G

acyl-CoA synthetase family member 2

increases expression

Diquat results in increased expression of ACSF2 mRNA

NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673

G

acyl-CoA synthetase long-chain family member 1

increases expression
decreases expression

Diquat results in increased expression of ACSL1 mRNA
Diquat results in decreased expression of ACSL1 protein

PMID:36851058 PMID:38128689

NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541

G

acyl-CoA synthetase long-chain family member 3

decreases expression

Diquat results in decreased expression of ACSL3 protein

NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627

G

acyl-CoA synthetase long-chain family member 4

decreases expression

Diquat results in decreased expression of ACSL4 protein

NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427

G

actin, beta-like 2

decreases expression

Diquat results in decreased expression of ACTBL2 protein

NCBI chr 2:42,858,020...42,860,767
Ensembl chr 2:42,858,020...42,860,767

G

ADAM metallopeptidase domain 12

decreases expression

Diquat results in decreased expression of ADAM12 mRNA

NCBI chr 1:188,686,984...189,014,206
Ensembl chr 1:188,686,989...189,020,667

G

ADAM metallopeptidase domain 19

decreases expression

Diquat results in decreased expression of ADAM19 mRNA

NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105

G

ADAM metallopeptidase domain 22

increases expression

Diquat results in increased expression of ADAM22 protein

NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962

G

ADAM metallopeptidase with thrombospondin type 1 motif, 2

decreases expression

Diquat results in decreased expression of ADAMTS2 mRNA

NCBI chr10:34,920,992...35,126,465
Ensembl chr10:34,921,049...35,123,821

G

ADAM metallopeptidase with thrombospondin type 1 motif, 5

decreases expression

Diquat results in decreased expression of ADAMTS5 mRNA

NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205

G

adhesion G protein-coupled receptor G1

increases expression

Diquat results in increased expression of ADGRG1 protein

NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108

G

adhesion G protein-coupled receptor G4

decreases expression

Diquat results in decreased expression of ADGRG4 mRNA

NCBI chr X:134,734,610...134,864,449
Ensembl chr X:134,854,736...134,864,449

G

adhesion G protein-coupled receptor L4

decreases expression

Diquat results in decreased expression of ADGRL4 mRNA

NCBI chr 2:240,354,909...240,457,231
Ensembl chr 2:240,354,941...240,457,225

G

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

decreases expression

Diquat results in decreased expression of ADH7 protein

NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182

G

adrenomedullin

increases expression

Diquat results in increased expression of ADM mRNA

PMID:21172416 PMID:36851058

NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654

G

adenosine A2B receptor

increases expression

Diquat results in increased expression of ADORA2B mRNA

PMID:21172416 PMID:36851058

NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772

G

adrenoceptor alpha 1D

increases expression

Diquat results in increased expression of ADRA1D mRNA

NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354

G

adrenoceptor alpha 2B

increases expression

Diquat results in increased expression of ADRA2B mRNA

NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355

G

alkylglycerone phosphate synthase

decreases expression

Diquat results in decreased expression of AGPS mRNA

NCBI chr 3:60,747,323...60,845,831
Ensembl chr 3:60,747,323...60,845,830

G

angiotensinogen

increases expression

Diquat results in increased expression of AGT mRNA

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

G

alpha-2-HS-glycoprotein

increases expression

Diquat results in increased expression of AHSG protein

NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999

G

adenylate kinase 5

decreases expression

Diquat results in decreased expression of AK5 mRNA

NCBI chr 2:241,397,297...241,581,483
Ensembl chr 2:241,397,297...241,581,458

G

aldo-keto reductase family 1 member B1

decreases expression

Diquat results in decreased expression of AKR1B1 mRNA

NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157

G

aldo-keto reductase family 1 member B10

increases expression

Diquat results in increased expression of AKR1B10 mRNA

NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852

G

aldo-keto reductase family 1, member C1

increases expression

Diquat results in increased expression of AKR1C1 mRNA

NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326

G

aldo-keto reductase family 1, member C2

increases expression

Diquat results in increased expression of AKR1C2 mRNA

NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764

G

AKT serine/threonine kinase 1

multiple interactions
increases phosphorylation

PROP1 protein affects the reaction [Diquat results in increased phosphorylation of AKT1 protein]

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

5'-aminolevulinate synthase 1

increases expression

Diquat results in increased expression of ALAS1 mRNA

NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917

G

aldehyde dehydrogenase 1 family, member A1

increases expression

Diquat results in increased expression of ALDH1A1 mRNA; Diquat results in increased expression of ALDH1A1 protein

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 1 family, member A2

decreases expression

Diquat results in decreased expression of ALDH1A2 protein

NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107

G

aldehyde dehydrogenase 1 family, member A3

decreases expression

Diquat results in decreased expression of ALDH1A3 mRNA

NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436

G

aldehyde dehydrogenase 1 family, member L1

increases expression

Diquat results in increased expression of ALDH1L1 mRNA

NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465

G

aldehyde dehydrogenase 3 family, member B1

increases expression

Diquat results in increased expression of ALDH3B1 mRNA

NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921

G

arachidonate 15-lipoxygenase

increases expression

Diquat results in increased expression of ALOX15 mRNA

NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874

G

alkaline phosphatase, biomineralization associated

increases expression

Diquat results in increased expression of ALPL mRNA

NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446

G

ALX homeobox 1

decreases expression

Diquat results in decreased expression of ALX1 mRNA

NCBI chr 7:38,157,626...38,177,220
Ensembl chr 7:38,147,117...38,177,220

G

alpha-methylacyl-CoA racemase

decreases expression

Diquat results in decreased expression of AMACR mRNA

NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255

G

angiopoietin 2

decreases expression

Diquat results in decreased expression of ANGPT2 mRNA

NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804

G

angiopoietin-like 4

increases expression

Diquat results in increased expression of ANGPTL4 mRNA

NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519

G

angiopoietin like 7

decreases expression

Diquat results in decreased expression of ANGPTL7 mRNA

NCBI chr 5:158,932,096...158,937,281
Ensembl chr 5:158,932,794...158,937,324

G

angiopoietin-like 8

increases expression

Diquat results in increased expression of ANGPTL8 mRNA

NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490

G

ankyrin repeat domain 1

increases expression

Diquat results in increased expression of ANKRD1 mRNA

NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919

G

ankyrin repeat domain 13a

decreases expression

Diquat results in decreased expression of ANKRD13A protein

NCBI chr12:41,798,196...41,828,327
Ensembl chr12:41,798,199...41,829,327

G

ankyrin repeat domain 34B

decreases expression

Diquat results in decreased expression of ANKRD34B mRNA

NCBI chr 2:23,651,083...23,668,041
Ensembl chr 2:23,651,474...23,668,030

G

ankyrin repeat and sterile alpha motif domain containing 1B

decreases expression

Diquat results in decreased expression of ANKS1B mRNA

NCBI chr 7:24,313,339...25,479,307
Ensembl chr 7:24,312,843...25,477,693

G

anoctamin 4

decreases expression

Diquat results in decreased expression of ANO4 mRNA

NCBI chr 7:23,329,015...23,738,423
Ensembl chr 7:23,329,070...23,738,434

G

anoctamin 5

decreases expression

Diquat results in decreased expression of ANO5 mRNA

NCBI chr 1:101,086,490...101,187,547
Ensembl chr 1:101,087,341...101,187,555

G

aldehyde oxidase 1

increases expression

Diquat results in increased expression of AOX1 mRNA

NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770

G

amyloid beta precursor protein binding family B member 1 interacting protein

decreases expression

Diquat results in decreased expression of APBB1IP mRNA

NCBI chr17:84,941,404...85,033,020
Ensembl chr17:84,982,243...85,033,010

G

amyloid beta precursor protein binding family B member 2

decreases expression

Diquat results in decreased expression of APBB2 protein

NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495

G

amyloid P component, serum

decreases expression

Diquat results in decreased expression of APCS mRNA

NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298

G

apelin receptor

decreases expression

Diquat results in decreased expression of APLNR mRNA

NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050

G

apolipoprotein A2

increases expression

Diquat results in increased expression of APOA2 protein

NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355

G

apolipoprotein A4

increases expression

Diquat results in increased expression of APOA4 mRNA

NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469

G

apolipoprotein C3

increases expression
decreases expression

Diquat results in increased expression of APOC3 mRNA
Diquat results in decreased expression of APOC3 protein

NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583

G

apolipoprotein D

increases expression

Diquat results in increased expression of APOD mRNA

NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305

G

apolipoprotein E

increases expression

Diquat results in increased expression of APOE mRNA

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

apolipoprotein H

increases expression

Diquat results in increased expression of APOH mRNA

NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329

G

apolipoprotein M

decreases expression

Diquat results in decreased expression of APOM protein

NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550

G

aquaporin 1

increases expression

Diquat results in increased expression of AQP1 protein

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

G

aquaporin 3 (Gill blood group)

increases expression

Diquat results in increased expression of AQP3 protein

NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720

G

aquaporin 4

decreases expression

Diquat results in decreased expression of AQP4 protein

NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856

G

aquaporin 8

increases expression

Diquat results in increased expression of AQP8 mRNA

NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158

G

amphiregulin

increases expression

Diquat results in increased expression of AREG mRNA

NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535

G

arginase 2

increases expression

Diquat results in increased expression of ARG2 mRNA

NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378

G

Rho GTPase activating protein 30

decreases expression

Diquat results in decreased expression of ARHGAP30 mRNA

NCBI chr13:83,822,290...83,843,634
Ensembl chr13:83,822,283...83,854,885

G

Rho GTPase activating protein 35

decreases expression

Diquat results in decreased expression of ARHGAP35 protein

NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298

G

Rac/Cdc42 guanine nucleotide exchange factor 6

decreases expression

Diquat results in decreased expression of ARHGEF6 protein

NCBI chr X:135,145,447...135,264,636
Ensembl chr X:135,146,786...135,275,304

G

armadillo repeat containing 12

increases expression

Diquat results in increased expression of ARMC12 mRNA

NCBI chr20:6,587,859...6,598,355
Ensembl chr20:6,587,859...6,598,352

G

armadillo-like helical domain containing 4

decreases expression

Diquat results in decreased expression of ARMH4 mRNA

NCBI chr15:22,975,895...23,076,986
Ensembl chr15:22,975,895...23,076,949

G

ADP-ribosyltransferase 4

decreases expression

Diquat results in decreased expression of ART4 protein

NCBI chr 4:169,740,331...169,751,571
Ensembl chr 4:169,740,331...169,750,665

G

ankyrin repeat and SOCS box containing 11

increases expression

Diquat results in increased expression of ASB11 mRNA

NCBI chr X:30,014,485...30,037,808
Ensembl chr X:29,992,416...30,037,807

G

ankyrin repeat and SOCS box-containing 9

increases expression

Diquat results in increased expression of ASB9 protein

NCBI chr X:29,956,576...30,001,436
Ensembl chr X:29,956,576...30,001,105

G

astrotactin 1

decreases expression

Diquat results in decreased expression of ASTN1 mRNA

NCBI chr13:70,537,423...70,855,440
Ensembl chr13:70,537,703...70,855,440

G

ASXL transcriptional regulator 3

decreases expression

Diquat results in decreased expression of ASXL3 mRNA

NCBI chr18:13,593,529...13,766,324
Ensembl chr18:13,593,985...13,762,427

G

activating transcription factor 3

increases expression

Diquat results in increased expression of ATF3 mRNA

PMID:21172416 PMID:36851058

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 5

increases expression

Diquat results in increased expression of ATF5 mRNA

NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707

G

activating transcription factor 6

increases expression

Diquat results in increased expression of ATF6 mRNA

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

autophagy related 12

multiple interactions

[Diquat co-treated with procyanidin B2] results in increased expression of ATG12 mRNA

NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418

G

autophagy related 5

increases expression

Diquat results in increased expression of ATG5 protein

NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209

G

autophagy related 9B

decreases expression

Diquat results in decreased expression of ATG9B mRNA

NCBI chr 4:10,784,934...10,793,832
Ensembl chr 4:10,786,114...10,793,651

G

antioxidant 1 copper chaperone

decreases expression

Diquat results in decreased expression of ATOX1 protein

NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950

G

ATPase phospholipid transporting 11A

decreases expression

Diquat results in decreased expression of ATP11A mRNA

NCBI chr16:76,657,752...76,767,640
Ensembl chr16:76,657,752...76,767,640

G

ATP synthase F1 subunit epsilon

increases expression

Diquat results in increased expression of ATP5F1E protein

NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450

G

ATP synthase membrane subunit c locus 1

increases expression

Diquat results in increased expression of ATP5MC1 protein

NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124

G

ATP synthase peripheral stalk subunit d

increases expression

Diquat results in increased expression of ATP5PD protein

NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479

G

ATPase H+ transporting V0 subunit a2

decreases expression

Diquat results in decreased expression of ATP6V0A2 protein

NCBI chr12:31,947,220...31,979,875
Ensembl chr12:31,822,733...32,007,069

G

ATPase H+ transporting V0 subunit a4

increases expression

Diquat results in increased expression of ATP6V0A4 mRNA

NCBI chr 4:66,760,163...66,842,126
Ensembl chr 4:66,760,159...66,842,110

G

ATPase H+ transporting V1 subunit G3

increases expression

Diquat results in increased expression of ATP6V1G3 protein

NCBI chr13:49,800,256...49,825,247
Ensembl chr13:49,794,222...49,825,247

G

ATPase phospholipid transporting 8B1

decreases expression

Diquat results in decreased expression of ATP8B1 protein

NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396

G

ATRX, chromatin remodeler

increases expression

Diquat results in increased expression of ATRX protein

NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330

G

beta-1,4-galactosyltransferase 1

decreases expression

Diquat results in decreased expression of B4GALT1 protein

NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461

G

beta-1,4-galactosyltransferase 5

decreases expression

Diquat results in decreased expression of B4GALT5 mRNA

NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074

G

BAG cochaperone 2

increases expression

Diquat results in increased expression of BAG2 mRNA; Diquat results in increased expression of BAG2 protein

NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721

G

BCL2 associated X, apoptosis regulator

multiple interactions
affects expression
increases expression

procyanidin B2 affects the reaction [Diquat affects the expression of BAX mRNA]
Diquat results in increased expression of BAX protein

PMID:26785375 PMID:27057282 PMID:38128689

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

gamma-butyrobetaine hydroxylase 1

increases expression

Diquat results in increased expression of BBOX1 mRNA

NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458

G

BCAS2, pre-mRNA processing factor

decreases expression

Diquat results in decreased expression of BCAS2 protein

NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389

G

branched chain amino acid transaminase 1

decreases expression

Diquat results in decreased expression of BCAT1 mRNA; Diquat results in decreased expression of BCAT1 protein

NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597

G

BCL10, immune signaling adaptor

decreases expression

Diquat results in decreased expression of BCL10 protein

NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523

G

BCL2, apoptosis regulator

affects expression
multiple interactions
decreases expression

Diquat affects the expression of BCL2 mRNA
procyanidin B2 affects the reaction [Diquat affects the expression of BCL2 mRNA]
Diquat results in decreased expression of BCL2 protein

PMID:26785375 PMID:27057282 PMID:29484840

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

increases expression

Diquat results in increased expression of BCL2L1 mRNA

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

G

Bcl2-like 11

increases expression
multiple interactions

Diquat results in increased expression of BCL2L11 mRNA
procyanidin B2 inhibits the reaction [Diquat results in increased expression of BCL2L11 mRNA]

PMID:26785375 PMID:27057282

NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068

G

BCL6B, transcription repressor

decreases expression

Diquat results in decreased expression of BCL6B mRNA

NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974

G

bradykinin receptor B2

increases expression

Diquat results in increased expression of BDKRB2 mRNA

NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497

G

beclin 1

multiple interactions

[Diquat co-treated with procyanidin B2] results in increased expression of BECN1 mRNA

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

biglycan

decreases expression

Diquat results in decreased expression of BGN mRNA

NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461

G

betaine-homocysteine S-methyltransferase

increases expression

Diquat results in increased expression of BHMT mRNA

NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742

G

BICD cargo adaptor 1

decreases expression

Diquat results in decreased expression of BICD1 protein

NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434

G

biliverdin reductase B

increases expression

Diquat results in increased expression of BLVRB mRNA

NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375

G

bone morphogenetic protein 6

increases expression

Diquat results in increased expression of BMP6 mRNA

NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365

G

BOP1 ribosomal biogenesis factor

decreases expression

Diquat results in decreased expression of BOP1 protein

NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931

G

BRO1 domain and CAAX motif containing

increases expression

Diquat results in increased expression of BROX protein

NCBI chr13:94,920,107...94,940,189
Ensembl chr13:94,920,112...94,940,227

G

bone marrow stromal cell antigen 2

decreases expression

Diquat results in decreased expression of BST2 mRNA

NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979

G

Bruton tyrosine kinase

decreases expression

Diquat results in decreased expression of BTK mRNA

NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853

G

butyrophilin-like 9

decreases expression

Diquat results in decreased expression of BTNL9 mRNA

NCBI chr10:33,466,059...33,489,229
Ensembl chr10:33,470,536...33,489,025

G

C1q and TNF related 2

decreases expression

Diquat results in decreased expression of C1QTNF2 mRNA

NCBI chr10:27,941,948...27,958,926
Ensembl chr10:27,941,948...27,959,185

G

C1q and TNF related 3

decreases expression

Diquat results in decreased expression of C1QTNF3 mRNA

NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433

G

complement C1s

decreases expression

Diquat results in decreased expression of C1S1 protein

NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303

G

complement C3

increases expression

Diquat results in increased expression of C3 mRNA

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

G

complement C7

decreases expression

Diquat results in decreased expression of C7 mRNA

NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535

G

complement C8 alpha chain

decreases expression

Diquat results in decreased expression of C8A mRNA

NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754

G

cell adhesion molecule 3

decreases expression

Diquat results in decreased expression of CADM3 protein

NCBI chr13:85,784,785...85,817,412
Ensembl chr13:85,786,483...85,817,749

G

calcium modulating ligand

decreases expression

Diquat results in decreased expression of CAMLG protein

NCBI chr17:8,992,697...9,003,576
Ensembl chr17:8,992,696...9,003,552

G

capping actin protein, gelsolin like

increases expression

Diquat results in increased expression of CAPG mRNA

NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856

G

carbonic anhydrase 5A

increases expression

Diquat results in increased expression of CAR5A mRNA

NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906

G

caspase recruitment domain family, member 11

decreases expression

Diquat results in decreased expression of CARD11 mRNA

NCBI chr12:13,621,140...13,758,115
Ensembl chr12:13,621,087...13,758,112

G

caspase 3

multiple interactions
increases cleavage
increases expression

Deferoxamine inhibits the reaction [Diquat results in increased cleavage of CASP3 protein]; Glutathione inhibits the reaction [Diquat results in increased cleavage of CASP3 protein]; GPX4 protein inhibits the reaction [Diquat results in increased cleavage of CASP3 protein]
[Antioxidants results in decreased susceptibility to Diquat] which results in decreased expression of CASP3 mRNA; Diquat results in increased cleavage of and results in increased activity of CASP3 protein; procyanidin B2 inhibits the reaction [Diquat results in increased expression of CASP3 mRNA]; TXN2 protein affects the reaction [Diquat results in increased cleavage of and results in increased activity of CASP3 protein]
Diquat results in increased expression of CASP3 mRNA; Diquat results in increased expression of CASP3 protein modified form
Acetylcysteine inhibits the reaction [Diquat results in increased expression of CASP3 protein modified form]; Meloxicam inhibits the reaction [Diquat results in increased expression of CASP3 protein modified form]; pifithrin inhibits the reaction [Diquat results in increased expression of CASP3 protein modified form]; SN50 peptide inhibits the reaction [Diquat results in increased expression of CASP3 protein modified form]

PMID:15496407 PMID:18164269 PMID:19815060 PMID:26785375 PMID:27057282 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 8

multiple interactions

[Antioxidants results in decreased susceptibility to Diquat] which results in decreased expression of CASP8 mRNA

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

multiple interactions
increases cleavage
increases expression

Diquat results in increased cleavage of and results in increased activity of CASP9 protein; PROP1 protein affects the reaction [Diquat results in increased cleavage of CASP9 protein]; TXN2 protein affects the reaction [Diquat results in increased cleavage of and results in increased activity of CASP9 protein]
Diquat results in increased expression of CASP9 protein modified form
Meloxicam inhibits the reaction [Diquat results in increased expression of CASP9 protein modified form]

PMID:18164269 PMID:20826540 PMID:29484840 PMID:38128689

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

multiple interactions
decreases activity
decreases expression
increases activity

CAT protein inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydrogen Peroxide]
3,4-dihydroxyphenylethanol inhibits the reaction [Diquat results in decreased activity of CAT protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [Diquat results in decreased expression of CAT mRNA]; CAT protein inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydrogen Peroxide]; procyanidin B2 inhibits the reaction [Diquat results in decreased activity of CAT protein]
Diquat results in increased activity of CAT protein

PMID:21215309 PMID:26785375 PMID:27057282 PMID:36572071 PMID:37277018

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

cation channel, sperm associated 1

increases expression

Diquat results in increased expression of CATSPER1 protein

NCBI chr 1:202,643,009...202,652,059
Ensembl chr 1:202,643,038...202,651,824

G

carbonyl reductase 1

increases expression

Diquat results in increased expression of CBR1 mRNA

NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393

G

carbonyl reductase 3

increases expression

Diquat results in increased expression of CBR3 mRNA

NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875

G

chromobox 3

increases expression

Diquat results in increased expression of CBX3 protein

NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283

G

chromobox 8

decreases expression

Diquat results in decreased expression of CBX8 protein

NCBI chr10:104,294,518...104,296,956
Ensembl chr10:104,294,518...104,297,024

G

coiled-coil domain containing 115

decreases expression

Diquat results in decreased expression of CCDC115 protein

NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946

G

coiled-coil domain containing 124

decreases expression

Diquat results in decreased expression of CCDC124 protein

NCBI chr16:18,566,745...18,572,564
Ensembl chr16:18,566,745...18,572,564

G

coiled-coil domain containing 167

decreases expression

Diquat results in decreased expression of CCDC167 protein

NCBI chr20:7,763,927...7,782,090
Ensembl chr20:7,751,782...7,781,613

G

coiled-coil domain containing 175

increases expression

Diquat results in increased expression of CCDC175 protein

NCBI chr 6:90,661,948...90,745,015
Ensembl chr 6:90,662,269...90,744,963

G

coiled-coil domain containing 180

decreases expression

Diquat results in decreased expression of CCDC180 mRNA

NCBI chr 5:60,154,883...60,223,508
Ensembl chr 5:60,154,910...60,223,522

G

coiled-coil domain 40 molecular ruler complex subunit

decreases expression

Diquat results in decreased expression of CCDC40 mRNA

NCBI chr10:104,486,748...104,527,284
Ensembl chr10:104,486,748...104,527,243

G

coiled-coil domain containing 80

decreases expression

Diquat results in decreased expression of CCDC80 mRNA

NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137

G

coiled-coil domain containing 85C

decreases expression

Diquat results in decreased expression of CCDC85C protein

NCBI chr 6:127,113,440...127,184,328
Ensembl chr 6:127,113,442...127,184,371

G

cellular communication network factor 2

decreases expression

Diquat results in decreased expression of CCN2 mRNA

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cyclin A2

decreases expression

Diquat results in decreased expression of CCNA2 mRNA

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B1

decreases expression

Diquat results in decreased expression of CCNB1 mRNA

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

C-C motif chemokine receptor 7

decreases expression

Diquat results in decreased expression of CCR7 mRNA

NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309

G

CD180 molecule

decreases expression

Diquat results in decreased expression of CD180 mRNA

NCBI chr 2:33,855,940...33,870,046
Ensembl chr 2:33,855,991...33,899,936

G

CD22 molecule

decreases expression

Diquat results in decreased expression of CD22 mRNA

NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322

G

CD274 molecule

decreases expression

Diquat results in decreased expression of CD274 mRNA

NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450

G

Cd28 molecule

decreases expression

Diquat results in decreased expression of CD28 mRNA

NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685

G

Cd300 molecule-like family member D

decreases expression

Diquat results in decreased expression of CD300LD mRNA

NCBI chr10:100,082,957...100,115,853
Ensembl chr10:100,083,490...100,115,821

G

CD34 molecule

decreases expression

Diquat results in decreased expression of CD34 mRNA

NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832

G

CD40 molecule

decreases expression

Diquat results in decreased expression of CD40 mRNA

NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534

G

CD44 molecule

decreases expression

Diquat results in decreased expression of CD44 mRNA

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

G

CD52 molecule

decreases expression

Diquat results in decreased expression of CD52 mRNA

NCBI chr 5:146,319,789...146,321,348
Ensembl chr 5:146,319,969...146,321,348

G

Cd53 molecule

decreases expression

Diquat results in decreased expression of CD53 mRNA

NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657

G

Cd5 molecule-like

decreases expression

Diquat results in decreased expression of CD5L protein

NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753

G

Cd72 molecule

decreases expression

Diquat results in decreased expression of CD72 mRNA

NCBI chr 5:57,697,361...57,704,980
Ensembl chr 5:57,697,367...57,704,725

G

CD74 molecule

decreases expression

Diquat results in decreased expression of CD74 mRNA

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

G

Cd81 molecule

increases expression

Diquat results in increased expression of CD81 protein

NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660

G

Cd82 molecule

increases expression

Diquat results in increased expression of CD82 protein

NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809

G

cell division cycle 20

decreases expression

Diquat results in decreased expression of CDC20 mRNA

NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512

G

cell division cycle 34, ubiqiutin conjugating enzyme

increases expression

Diquat results in increased expression of CDC34 mRNA

NCBI chr 7:10,017,588...10,023,586
Ensembl chr 7:10,017,588...10,023,186

G

cell division cycle 37-like 1

increases expression

Diquat results in increased expression of CDC37L1 protein

NCBI chr 1:226,705,019...226,733,994
Ensembl chr 1:226,705,003...226,761,175

G

cadherin 11

decreases expression

Diquat results in decreased expression of CDH11 mRNA

NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272

G

cyclin-dependent kinase 1

decreases expression

Diquat results in decreased expression of CDK1 mRNA

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase 7

increases expression

Diquat results in increased expression of CDK7 protein

NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383

G

CDK5 regulatory subunit associated protein 1-like 1

decreases expression

Diquat results in decreased expression of CDKAL1 protein

NCBI chr17:34,718,701...35,271,276
Ensembl chr17:34,718,687...35,407,524

G

cyclin-dependent kinase inhibitor 1A

increases expression

Diquat results in increased expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

CDP-diacylglycerol synthase 1

decreases expression

Diquat results in decreased expression of CDS1 protein

NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681

G

CCAAT/enhancer binding protein alpha

increases expression

Diquat results in increased expression of CEBPA mRNA

NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412

G

CCAAT/enhancer binding protein beta

increases expression

Diquat results in increased expression of CEBPB mRNA

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

G

cell migration inducing hyaluronidase 2

decreases expression

Diquat results in decreased expression of CEMIP2 protein

NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760

G

centromere protein E

decreases expression

Diquat results in decreased expression of CENPE mRNA

NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669

G

centromere protein F

decreases expression

Diquat results in decreased expression of CENPF mRNA

NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669

G

carboxylesterase 2H

decreases expression

Diquat results in decreased expression of CES2H mRNA

NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830

G

cilia and flagella associated protein 20

decreases expression

Diquat results in decreased expression of CFAP20 protein

NCBI chr19:9,608,867...9,622,558
Ensembl chr19:9,608,859...9,622,558

G

cilia and flagella associated protein 70

decreases expression

Diquat results in decreased expression of CFAP70 mRNA

NCBI chr15:3,852,381...3,918,036
Ensembl chr15:3,852,509...3,918,014

G

complement factor B

decreases expression

Diquat results in decreased expression of CFB mRNA

NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505

G

complement factor H

decreases expression

Diquat results in decreased expression of CFH mRNA

NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838

G

coiled-coil-helix-coiled-coil-helix domain containing 1

decreases expression

Diquat results in decreased expression of CHCHD1 protein

NCBI chr15:3,592,719...3,593,901
Ensembl chr15:3,592,727...3,593,901

G

coiled-coil-helix-coiled-coil-helix domain containing 10

increases expression

Diquat results in increased expression of CHCHD10 mRNA

NCBI chr20:12,725,839...12,727,638
Ensembl chr20:12,725,842...12,732,763

G

coiled-coil-helix-coiled-coil-helix domain containing 2

decreases expression

Diquat results in decreased expression of CHCHD2 protein

NCBI chr12:26,828,738...26,834,762
Ensembl chr12:26,828,736...26,834,755

G

calcineurin-like EF-hand protein 1

increases expression

Diquat results in increased expression of CHP1 protein

NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251

G

chordin-like 2

increases expression

Diquat results in increased expression of CHRDL2 mRNA

NCBI chr 1:154,343,201...154,370,651
Ensembl chr 1:154,343,201...154,370,640

G

cholinergic receptor nicotinic alpha 2 subunit

increases expression

Diquat results in increased expression of CHRNA2 mRNA

NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601

G

carbohydrate sulfotransferase 13

increases expression

Diquat results in increased expression of CHST13 mRNA

NCBI chr 4:122,824,022...122,837,940
Ensembl chr 4:122,824,022...122,838,019

G

carbohydrate sulfotransferase 2

decreases expression

Diquat results in decreased expression of CHST2 mRNA

NCBI chr 8:95,960,067...95,966,312
Ensembl chr 8:95,959,826...95,966,955

G

component of inhibitor of nuclear factor kappa B kinase complex

increases expression

Diquat results in increased expression of CHUK protein

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

G

cell death-inducing DFFA-like effector c

increases expression

Diquat results in increased expression of CIDEC mRNA

NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4

increases expression

Diquat results in increased expression of CITED4 mRNA

NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135

G

cytoskeleton associated protein 2

decreases expression

Diquat results in decreased expression of CKAP2 mRNA

NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913

G

cytoskeleton associated protein 2-like

decreases expression

Diquat results in decreased expression of CKAP2L mRNA

NCBI chr 3:116,497,186...116,524,302
Ensembl chr 3:116,498,022...116,524,366

G

cardiotrophin-like cytokine factor 1

increases expression

Diquat results in increased expression of CLCF1 mRNA

NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605

G

chloride voltage-gated channel 4

decreases expression

Diquat results in decreased expression of CLCN4 protein

NCBI chr X:23,729,194...23,795,391
Ensembl chr X:23,729,338...23,793,238

G

claudin 14

increases expression

Diquat results in increased expression of CLDN14 mRNA

NCBI chr11:33,232,281...33,329,440
Ensembl chr11:33,232,220...33,329,171

G

claudin 18

decreases expression

Diquat results in decreased expression of CLDN18 mRNA

NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351

G

claudin 4

increases expression

Diquat results in increased expression of CLDN4 mRNA

NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436

G

claudin 8

increases expression

Diquat results in increased expression of CLDN8 protein

NCBI chr11:27,875,857...27,878,106
Ensembl chr11:27,875,692...27,878,513

G

C-type lectin domain family 12, member A

decreases expression

Diquat results in decreased expression of CLEC12A mRNA

NCBI chr 4:162,798,125...162,816,757
Ensembl chr 4:162,798,125...162,816,753

G

C-type lectin domain family 3, member B

decreases expression

Diquat results in decreased expression of CLEC3B protein

NCBI chr 8:122,810,120...122,815,837
Ensembl chr 8:122,810,149...122,815,835

G

C-type lectin domain containing 9A

decreases expression

Diquat results in decreased expression of CLEC9A mRNA

NCBI chr 4:162,859,742...162,875,742
Ensembl chr 4:162,860,308...162,875,352

G

CAP-GLY domain containing linker protein family, member 4

increases expression

Diquat results in increased expression of CLIP4 mRNA

NCBI chr 6:23,616,280...23,697,625
NCBI chr 6:23,718,580...23,729,231
NCBI chr 6:23,597,729...23,601,000
Ensembl chr 6:23,616,281...23,677,874

G

CDC-like kinase 3

increases expression

Diquat results in increased expression of CLK3 protein

NCBI chr 8:58,152,155...58,167,196
Ensembl chr 8:58,152,155...58,168,181

G

claspin

decreases expression

Diquat results in decreased expression of CLSPN mRNA

NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034

G

calsyntenin 2

decreases expression

Diquat results in decreased expression of CLSTN2 mRNA

NCBI chr 8:98,020,406...98,637,232
Ensembl chr 8:98,021,666...98,637,731

G

collectrin, amino acid transport regulator

decreases expression

Diquat results in decreased expression of CLTRN protein

NCBI chr X:30,361,967...30,395,264
Ensembl chr X:30,361,967...30,395,349

G

c-Maf-inducing protein

decreases expression

Diquat results in decreased expression of CMIP protein

NCBI chr19:45,304,597...45,510,653
Ensembl chr19:45,304,031...45,508,709

G

CKLF-like MARVEL transmembrane domain containing 3

decreases expression

Diquat results in decreased expression of CMTM3 mRNA

NCBI chr19:622,563...630,721
Ensembl chr19:604,458...629,790

G

carnosine dipeptidase 2

decreases expression

Diquat results in decreased expression of CNDP2 mRNA

NCBI chr18:78,039,924...78,057,030
Ensembl chr18:78,039,932...78,056,922

G

calponin 1

decreases expression

Diquat results in decreased expression of CNN1 protein

NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098

G

cyclin and CBS domain divalent metal cation transport mediator 4

increases expression

Diquat results in increased expression of CNNM4 mRNA

NCBI chr 9:38,711,726...38,750,942
Ensembl chr 9:38,711,710...38,750,942

G

CCR4-NOT transcription complex, subunit 7

increases expression

Diquat results in increased expression of CNOT7 protein

NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576

G

cannabinoid receptor interacting protein 1

decreases expression

Diquat results in decreased expression of CNRIP1 mRNA

NCBI chr14:91,462,877...91,492,739
Ensembl chr14:91,462,647...91,492,735

G

contactin 1

decreases expression

Diquat results in decreased expression of CNTN1 mRNA

NCBI chr 7:123,263,146...123,560,896
Ensembl chr 7:123,372,792...123,558,541

G

contactin 5

decreases expression

Diquat results in decreased expression of CNTN5 mRNA

NCBI chr 8:6,735,715...7,967,727
Ensembl chr 8:6,738,239...7,967,957

G

contactin associated protein family member 5B

decreases expression

Diquat results in decreased expression of CNTNAP5A mRNA

NCBI chr13:17,863,367...18,766,983
Ensembl chr13:18,093,420...18,761,014

G

collagen type XIII alpha 1 chain

increases expression

Diquat results in increased expression of COL13A1 mRNA

NCBI chr20:29,783,965...29,924,116
Ensembl chr20:29,783,965...29,924,032

G

collagen type XIV alpha 1 chain

decreases expression

Diquat results in decreased expression of COL14A1 mRNA

NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214

G

collagen type XV alpha 1 chain

decreases expression

Diquat results in decreased expression of COL15A1 mRNA

NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591

G

collagen type XIX alpha 1 chain

decreases expression

Diquat results in decreased expression of COL19A1 mRNA

NCBI chr 9:26,673,916...27,022,139
Ensembl chr 9:26,675,391...27,022,106

G

collagen type I alpha 1 chain

decreases expression

Diquat results in decreased expression of COL1A1 mRNA

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type I alpha 2 chain

decreases expression

Diquat results in decreased expression of COL1A2 mRNA

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

G

collagen type III alpha 1 chain

decreases expression

Diquat results in decreased expression of COL3A1 mRNA

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

G

collagen type V alpha 1 chain

decreases expression

Diquat results in decreased expression of COL5A1 mRNA

NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588

G

collagen type V alpha 2 chain

decreases expression

Diquat results in decreased expression of COL5A2 mRNA

NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154

G

collagen type VI alpha 3 chain

decreases expression

Diquat results in decreased expression of COL6A3 mRNA

NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471

G

collagen type VI alpha 6 chain

decreases expression

Diquat results in decreased expression of COL6A6 mRNA

NCBI chr 8:106,318,010...106,473,419
Ensembl chr 8:106,306,422...106,473,472

G

collectin sub-family member 11

decreases expression

Diquat results in decreased expression of COLEC11 mRNA

NCBI chr 6:45,223,974...45,256,640
Ensembl chr 6:45,223,980...45,271,145

G

collectin sub-family member 12

decreases expression

Diquat results in decreased expression of COLEC12 mRNA

NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618

G

coronin 1A

decreases expression

Diquat results in decreased expression of CORO1A mRNA

NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534

G

coactosin-like F-actin binding protein 1

increases expression

Diquat results in increased expression of COTL1 mRNA

NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689

G

cytochrome c oxidase assembly factor COX20

decreases expression

Diquat results in decreased expression of COX20 protein

NCBI chr13:90,065,900...90,075,386

G

cytochrome c oxidase subunit 4i1

decreases expression

Diquat results in decreased expression of COX4I1 protein

NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921

G

cytochrome c oxidase subunit 6B2

increases expression

Diquat results in increased expression of COX6B2 mRNA

NCBI chr 1:69,094,009...69,095,312

G

carboxypeptidase M

decreases expression

Diquat results in decreased expression of CPM mRNA

NCBI chr 7:53,225,647...53,286,220
Ensembl chr 7:53,225,696...53,286,220

G

cleavage and polyadenylation specific factor 7

decreases expression

Diquat results in decreased expression of CPSF7 protein

NCBI chr 1:207,167,690...207,191,938
Ensembl chr 1:207,167,859...207,191,905

G

carnitine palmitoyltransferase 2

increases expression

Diquat results in increased expression of CPT2 mRNA

NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095

G

carboxypeptidase X (M14 family), member 1

decreases expression

Diquat results in decreased expression of CPXM1 mRNA

NCBI chr 3:117,588,532...117,595,330
Ensembl chr 3:117,588,532...117,595,330

G

CASP2 and RIPK1 domain containing adaptor with death domain

decreases expression

Diquat results in decreased expression of CRADD protein

NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907

G

cAMP responsive element binding protein 3-like 3

increases expression

Diquat results in increased expression of CREB3L3 mRNA

NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048

G

cellular repressor of E1A-stimulated genes 1

increases expression

Diquat results in increased expression of CREG1 mRNA; Diquat results in increased expression of CREG1 protein

NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308

G

cysteine-rich with EGF-like domains 1

increases expression

Diquat results in increased expression of CRELD1 mRNA

NCBI chr 4:146,631,883...146,641,493
Ensembl chr 4:146,631,883...146,641,499

G

cysteine-rich with EGF-like domains 2

increases expression

Diquat results in increased expression of CRELD2 mRNA

NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543

G

CDP-L-ribitol pyrophosphorylase A

decreases expression

Diquat results in decreased expression of CRPPA mRNA

NCBI chr 6:53,120,264...53,397,030
Ensembl chr 6:53,121,438...53,397,028

G

crystallin, alpha A

decreases expression

Diquat results in decreased expression of CRYAA mRNA

NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349

G

crystallin beta-gamma domain containing 2

increases expression

Diquat results in increased expression of CRYBG2 mRNA

NCBI chr 5:146,286,406...146,318,417
Ensembl chr 5:146,286,925...146,323,666

G

chondroitin sulfate N-acetylgalactosaminyltransferase 1

decreases expression

Diquat results in decreased expression of CSGALNACT1 mRNA

NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319

G

cysteine and glycine-rich protein 1

increases expression

Diquat results in increased expression of CSRP1 protein

NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384

G

CCCTC-binding factor like 1

increases expression

Diquat results in increased expression of CTCFL mRNA

NCBI chr 3:161,868,306...161,890,949
Ensembl chr 3:161,868,306...161,890,949

G

catenin alpha 2

decreases expression

Diquat results in decreased expression of CTNNA2 mRNA

NCBI chr 4:109,294,249...110,443,409
Ensembl chr 4:109,293,978...110,443,522

G

cathepsin S

decreases expression

Diquat results in decreased expression of CTSS mRNA

NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483

G

CWF19 like cell cycle control factor 1

increases expression

Diquat results in increased expression of CWF19L1 protein

NCBI chr 1:242,997,720...243,020,989
Ensembl chr 1:242,997,726...243,020,961

G

C-X3-C motif chemokine receptor 1

decreases expression

Diquat results in decreased expression of CX3CR1 mRNA

NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014

G

CXADR, Ig-like cell adhesion molecule

decreases expression

Diquat results in decreased expression of CXADR protein

NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046

G

C-X-C motif chemokine ligand 14

decreases expression

Diquat results in decreased expression of CXCL14 mRNA

NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839

G

C-X-C motif chemokine ligand 3

increases expression

Diquat results in increased expression of CXCL1 mRNA

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine ligand 9

decreases expression

Diquat results in decreased expression of CXCL9 mRNA

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

G

cytochrome b5 type B

increases expression

Diquat results in increased expression of CYB5B protein

NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249

G

cytochrome b-245 beta chain

decreases expression

Diquat results in decreased expression of CYBB mRNA

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

G

cytochrome P450, family 17, subfamily a, polypeptide 1

increases expression

Diquat results in increased expression of CYP17A1 mRNA

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 26, subfamily b, polypeptide 1

increases expression

Diquat results in increased expression of CYP26B1 mRNA

NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628

G

cytochrome P450, family 27, subfamily a, polypeptide 1

increases expression

Diquat results in increased expression of CYP27A1 mRNA

NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 27, subfamily b, polypeptide 1

increases expression

Diquat results in increased expression of CYP27B1 mRNA

NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241

G

cytochrome P450, family 2, subfamily a, polypeptide 3

decreases expression

Diquat results in decreased expression of CYP2A4 protein

NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979

G

cytochrome P450, family 2, subfamily b, polypeptide 3

increases expression

Diquat results in increased expression of CYP2B10 mRNA

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily d, polypeptide 4

increases expression

Diquat results in increased expression of CYP2D22 mRNA

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 2, subfamily f, polypeptide 4

increases expression

Diquat results in increased expression of CYP2F2 mRNA

NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896

G

cytochrome P450, family 3, subfamily a, polypeptide 2

decreases expression

Diquat results in decreased expression of CYP3A2 mRNA

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 4, subfamily a, polypeptide 1

increases expression

Diquat results in increased expression of CYP4A1 mRNA

NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464

G

cytochrome P450, family 51

decreases expression

Diquat results in decreased expression of CYP51 mRNA

NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410

G

cytohesin 4

decreases expression

Diquat results in decreased expression of CYTH4 mRNA

NCBI chr 7:110,152,232...110,176,726
Ensembl chr 7:110,152,272...110,176,741

G

dishevelled-binding antagonist of beta-catenin 1

decreases expression

Diquat results in decreased expression of DACT1 mRNA

NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906

G

D-amino-acid oxidase

multiple interactions
increases activity

Ascorbic Acid inhibits the reaction [Diquat results in increased activity of DAO protein]

NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741

G

DDB1 and CUL4 associated factor 8

decreases expression

Diquat results in decreased expression of DCAF8 protein

NCBI chr13:84,609,838...84,667,025
Ensembl chr13:84,610,248...84,669,726

G

dachsous cadherin-related 1

decreases expression

Diquat results in decreased expression of DCHS1 mRNA

NCBI chr 1:160,104,931...160,138,958
Ensembl chr 1:160,104,931...160,124,808

G

doublecortin-like kinase 2

decreases expression

Diquat results in decreased expression of DCLK2 mRNA

NCBI chr 2:172,202,733...172,338,411
Ensembl chr 2:172,208,706...172,338,250

G

DC-STAMP domain containing 1

decreases expression

Diquat results in decreased expression of DCST1 mRNA

NCBI chr 2:174,765,203...174,784,023
Ensembl chr 2:174,765,350...174,781,806

G

dynactin subunit 6

decreases expression

Diquat results in decreased expression of DCTN6 protein

NCBI chr16:58,077,595...58,096,604
Ensembl chr16:58,077,585...58,096,968

G

dopa decarboxylase

increases expression

Diquat results in increased expression of DDC mRNA

NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208

G

DNA-damage inducible transcript 3

increases expression
multiple interactions

Diquat results in increased expression of DDIT3 mRNA; Diquat results in increased expression of DDIT3 protein
PROP1 protein affects the reaction [Diquat results in increased expression of DDIT3 mRNA]; PROP1 protein affects the reaction [Diquat results in increased expression of DDIT3 protein]

PMID:20826540 PMID:36851058

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

discoidin domain receptor tyrosine kinase 2

decreases expression

Diquat results in decreased expression of DDR2 mRNA

NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363

G

DEAD-box helicase 4

decreases expression

Diquat results in decreased expression of DDX4 mRNA

NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723

G

DEAD-box helicase 49

decreases expression

Diquat results in decreased expression of DDX49 protein

NCBI chr16:19,125,388...19,133,042
Ensembl chr16:19,125,384...19,133,616

G

2,4-dienoyl-CoA reductase 2

increases expression

Diquat results in increased expression of DECR2 mRNA

NCBI chr10:15,104,907...15,113,281
Ensembl chr10:15,002,926...15,118,479

G

defensin beta 24

decreases expression

Diquat results in decreased expression of DEFB19 mRNA

NCBI chr 3:141,046,571...141,052,706
Ensembl chr 3:141,046,564...141,052,753

G

DEP domain containing 5, GATOR1 subcomplex subunit

decreases expression

Diquat results in decreased expression of DEPDC5 protein

NCBI chr14:77,732,297...77,862,924
Ensembl chr14:77,732,297...77,862,794

G

DEPP autophagy regulator 1

increases expression

Diquat results in increased expression of DEPP1 mRNA

NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542

G

diacylglycerol O-acyltransferase 2

increases expression

Diquat results in increased expression of DGAT2 mRNA

NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428

G

7-dehydrocholesterol reductase

decreases expression

Diquat results in decreased expression of DHCR7 protein

NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055

G

dickkopf WNT signaling pathway inhibitor 1

increases expression

Diquat results in increased expression of DKK1 mRNA

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

G

dickkopf WNT signaling pathway inhibitor 2

decreases expression

Diquat results in decreased expression of DKK2 mRNA

NCBI chr 2:220,568,338...220,660,225
Ensembl chr 2:220,568,338...220,660,225

G

discs large MAGUK scaffold protein 4

decreases expression

Diquat results in decreased expression of DLG4 protein

NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153

G

delta like canonical Notch ligand 4

decreases expression

Diquat results in decreased expression of DLL4 mRNA

NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931

G

dynein, axonemal, heavy chain 17

increases expression

Diquat results in increased expression of DNAH17 protein

NCBI chr10:103,244,144...103,364,953
Ensembl chr10:103,249,363...103,364,901

G

DnaJ heat shock protein family (Hsp40) member A3

decreases expression

Diquat results in decreased expression of DNAJA3 protein

NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161

G

DnaJ heat shock protein family (Hsp40) member B14

increases expression

Diquat results in increased expression of DNAJB14 protein

NCBI chr 2:226,358,988...226,409,461
Ensembl chr 2:226,358,996...226,402,490

G

DnaJ heat shock protein family (Hsp40) member C15

decreases expression

Diquat results in decreased expression of DNAJC15 protein

NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675

G

DnaJ heat shock protein family (Hsp40) member C5

increases expression

Diquat results in increased expression of DNAJC5 protein

NCBI chr 3:168,621,905...168,656,570
Ensembl chr 3:168,621,969...168,655,935

G

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

decreases expression

Diquat results in decreased expression of DNPH1 protein

NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022

G

dedicator of cytokinesis 2

decreases expression

Diquat results in decreased expression of DOCK2 mRNA

NCBI chr10:18,827,237...19,244,832
Ensembl chr10:18,827,239...19,244,808

G

dedicator of cytokinesis 4

increases expression

Diquat results in increased expression of DOCK4 protein

NCBI chr 6:57,512,929...57,902,597
Ensembl chr 6:57,512,908...57,901,855

G

dermatopontin

decreases expression

Diquat results in decreased expression of DPT mRNA

NCBI chr13:77,123,224...77,151,646
Ensembl chr13:77,123,115...77,151,639

G

dihydropyrimidinase

increases expression

Diquat results in increased expression of DPYS mRNA

NCBI chr 7:70,822,648...70,929,255
Ensembl chr 7:70,835,789...70,929,231

G

dihydropyrimidinase-like 3

decreases expression

Diquat results in decreased expression of DPYSL3 mRNA

NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157

G

dermatan sulfate epimerase-like

decreases expression

Diquat results in decreased expression of DSEL mRNA

NCBI chr13:186,413...192,592
Ensembl chr13:175,805...192,647

G

destrin, actin depolymerizing factor

increases expression

Diquat results in increased expression of DSTN protein

NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:131,284,648...131,311,379

G

dual serine/threonine and tyrosine protein kinase

decreases expression

Diquat results in decreased expression of DSTYK protein

NCBI chr13:43,857,266...43,905,280
Ensembl chr13:43,857,266...43,905,269

G

dual specificity phosphatase 1

increases expression

Diquat results in increased expression of DUSP1 mRNA

NCBI chr10:16,680,478...16,683,275

G

dual specificity phosphatase 8

increases expression

Diquat results in increased expression of DUSP8 mRNA

NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921

G

enoyl-CoA delta isomerase 1

increases expression

Diquat results in increased expression of ECI1 mRNA

NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061

G

extracellular matrix protein 2

decreases expression

Diquat results in decreased expression of ECM2 mRNA

NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516

G

EGF like repeats and discoidin domains 3

decreases expression

Diquat results in decreased expression of EDIL3 mRNA

NCBI chr 2:19,890,396...20,405,028
Ensembl chr 2:19,890,373...20,405,008

G

EGF-like-domain, multiple 6

decreases expression

Diquat results in decreased expression of EGFL6 mRNA

NCBI chr X:27,884,087...27,942,044
Ensembl chr X:27,884,125...27,942,044

G

EGF-like, fibronectin type III and laminin G domains

decreases expression

Diquat results in decreased expression of EGFLAM mRNA

NCBI chr 2:56,301,945...56,476,665
Ensembl chr 2:56,302,566...56,476,298

G

early growth response 1

multiple interactions
increases expression

PROP1 protein affects the reaction [Diquat results in increased expression of EGR1 mRNA]

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

EH-domain containing 4

decreases expression

Diquat results in decreased expression of EHD4 mRNA

NCBI chr 3:107,058,191...107,121,985
Ensembl chr 3:107,058,958...107,122,002

G

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

increases expression

Diquat results in increased expression of EHHADH mRNA

NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188

G

eukaryotic translation initiation factor 2 alpha kinase 3

increases expression

Diquat results in increased expression of EIF2AK3 mRNA

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

G

eukaryotic translation initiation factor 4E family member 2

increases expression

Diquat results in increased expression of EIF4E2 protein

NCBI chr 9:87,886,126...87,914,470
Ensembl chr 9:87,878,085...87,914,482

G

eukaryotic translation initiation factor 4E binding protein 1

increases expression

Diquat results in increased expression of EIF4EBP1 mRNA

NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984

G

eukaryotic translation initiation factor 4E binding protein 3

increases expression

Diquat results in increased expression of EIF4EBP3 mRNA

NCBI chr18:28,263,089...28,268,033
Ensembl chr18:28,162,311...28,268,024

G

eukaryotic translation initiation factor 6

increases expression

Diquat results in increased expression of EIF6 mRNA

NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401

G

elongation factor for RNA polymerase II 2

increases expression

Diquat results in increased expression of ELL2 mRNA

NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781

G

ELOVL fatty acid elongase 7

increases expression

Diquat results in increased expression of ELOVL7 protein

NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845

G

elongator acetyltransferase complex subunit 1

decreases expression

Diquat results in decreased expression of ELP1 protein

NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762

G

endomucin

increases expression

Diquat results in increased expression of EMCN protein

NCBI chr 2:225,891,100...225,970,932
Ensembl chr 2:225,891,100...225,970,929

G

EMI domain containing 1

decreases expression

Diquat results in decreased expression of EMID1 mRNA

NCBI chr14:80,000,486...80,043,561
Ensembl chr14:80,000,486...80,043,620

G

EMAP like 5

decreases expression

Diquat results in decreased expression of EML5 mRNA

NCBI chr 6:118,046,655...118,175,831
Ensembl chr 6:118,046,655...118,175,831

G

endonuclease, poly(U)-specific

increases expression

Diquat results in increased expression of ENDOU mRNA

NCBI chr 7:128,844,872...128,866,572
Ensembl chr 7:128,844,862...128,866,596

G

endo-beta-N-acetylglucosaminidase

decreases expression

Diquat results in decreased expression of ENGASE protein

NCBI chr10:103,707,169...103,719,833
Ensembl chr10:103,707,169...103,719,819

G

enolase 1

increases expression

Diquat results in increased expression of ENO1 mRNA

NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336

G

ecto-NOX disulfide-thiol exchanger 1

increases expression

Diquat results in increased expression of ENOX1 mRNA

NCBI chr15:52,517,833...53,079,752
Ensembl chr15:52,515,178...53,079,749

G

ectonucleoside triphosphate diphosphohydrolase 2

decreases expression

Diquat results in decreased expression of ENTPD2 protein

NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866

G

EGF domain specific O-linked N-acetylglucosamine transferase

decreases expression

Diquat results in decreased expression of EOGT protein

NCBI chr 4:129,718,897...129,756,558
Ensembl chr 4:129,718,901...129,756,445

G

erythrocyte membrane protein band 4.1-like 2

decreases expression

Diquat results in decreased expression of EPB41L2 mRNA

NCBI chr 1:19,863,010...20,037,795
Ensembl chr 1:19,863,009...20,037,721

G

Eph receptor A3

decreases expression

Diquat results in decreased expression of EPHA3 mRNA

NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900

G

Eph receptor A4

decreases expression

Diquat results in decreased expression of EPHA4 mRNA

NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139

G

Eph receptor B1

decreases expression

Diquat results in decreased expression of EPHB1 mRNA

NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839

G

ETS transcription factor ERG

decreases expression

Diquat results in decreased expression of ERG mRNA

NCBI chr11:34,678,614...34,900,951
Ensembl chr11:34,678,618...34,845,871

G

establishment of sister chromatid cohesion N-acetyltransferase 2

decreases expression

Diquat results in decreased expression of ESCO2 mRNA

NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306

G

endothelial cell-specific molecule 1

decreases expression

Diquat results in decreased expression of ESM1 mRNA

NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804

G

espin

increases expression

Diquat results in increased expression of ESPN protein

NCBI chr 5:162,626,560...162,660,439
Ensembl chr 5:162,626,560...162,660,256

G

estrogen receptor 1

decreases expression

Diquat results in decreased expression of ESR1 mRNA

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

ETHE1, persulfide dioxygenase

increases expression

Diquat results in increased expression of ETHE1 mRNA

NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052

G

ETS proto-oncogene 1, transcription factor

decreases expression

Diquat results in decreased expression of ETS1 mRNA

NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010

G

envoplakin

increases expression

Diquat results in increased expression of EVPL mRNA

NCBI chr10:101,458,227...101,474,778
Ensembl chr10:101,458,216...101,474,763

G

exostosin-like glycosyltransferase 1

increases expression

Diquat results in increased expression of EXTL1 mRNA

NCBI chr 5:146,573,911...146,589,115
Ensembl chr 5:146,573,912...146,589,115

G

coagulation factor II (thrombin) receptor

decreases expression

Diquat results in decreased expression of F2R mRNA

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

G

F2R like thrombin or trypsin receptor 3

decreases expression

Diquat results in decreased expression of F2RL3 mRNA

NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472

G

fatty acid binding protein 1

increases expression

Diquat results in increased expression of FABP1 mRNA

NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788

G

family with sequence similarity 163, member A

increases expression

Diquat results in increased expression of FAM163A mRNA

NCBI chr13:68,262,867...68,341,323
Ensembl chr13:68,262,872...68,341,049

G

FAM20A, golgi associated secretory pathway pseudokinase

increases expression

Diquat results in increased expression of FAM20A mRNA

NCBI chr10:94,638,836...94,697,814
Ensembl chr10:94,642,850...94,697,672

G

FAM20B, glycosaminoglycan xylosylkinase

decreases expression

Diquat results in decreased expression of FAM20B protein

NCBI chr13:68,801,663...68,839,979
Ensembl chr13:68,801,669...68,839,915

G

family with sequence similarity 25, member A

increases expression

Diquat results in increased expression of FAM25A mRNA

NCBI chr16:9,680,668...9,684,474
Ensembl chr16:9,680,668...9,684,474

G

family with sequence similarity 32, member A

decreases expression

Diquat results in decreased expression of FAM32A protein

NCBI chr16:17,603,054...17,607,376
Ensembl chr16:17,603,946...17,607,398

G

FANCD2 opposite strand

decreases expression

Diquat results in decreased expression of FANCD2OS mRNA

NCBI chr 4:146,740,863...146,747,547
Ensembl chr 4:146,740,863...146,747,569

G

fibulin 1

decreases expression

Diquat results in decreased expression of FBLN1 mRNA

NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075

G

fibulin 5

decreases expression

Diquat results in decreased expression of FBLN5 mRNA

NCBI chr 6:120,899,219...120,977,829
Ensembl chr 6:120,899,224...120,977,755

G

fibulin 7

decreases expression

Diquat results in decreased expression of FBLN7 mRNA

NCBI chr 3:116,111,581...116,145,839
Ensembl chr 3:116,111,677...116,147,983

G

fibrillin 1

decreases expression

Diquat results in decreased expression of FBN1 mRNA

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

G

fructose-bisphosphatase 2

increases expression

Diquat results in increased expression of FBP2 mRNA

NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698

G

F-box and leucine-rich repeat protein 17

increases expression

Diquat results in increased expression of FBXL17 protein

NCBI chr 9:102,780,573...103,206,978
Ensembl chr 9:102,782,440...103,208,950

G

F-box protein 44

increases expression

Diquat results in increased expression of FBXO44 protein

NCBI chr 5:158,583,363...158,592,510
Ensembl chr 5:158,583,366...158,592,363

G

Fc epsilon receptor Ig

decreases expression

Diquat results in decreased expression of FCER1G mRNA; Diquat results in decreased expression of FCER1G protein

NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443

G

Fc gamma binding protein

decreases expression

Diquat results in decreased expression of FCGBP mRNA

NCBI chr 1:83,374,979...83,413,082
Ensembl chr 1:83,372,127...83,413,083

G

fibrinogen alpha chain

increases expression

Diquat results in increased expression of FGA mRNA

NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528

G

fibrinogen beta chain

increases expression

Diquat results in increased expression of FGB mRNA

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

G

FYVE, RhoGEF and PH domain containing 5

decreases expression

Diquat results in decreased expression of FGD5 protein

NCBI chr 4:124,497,061...124,594,564
Ensembl chr 4:124,497,068...124,594,563

G

fibroblast growth factor 18

increases expression

Diquat results in increased expression of FGF18 mRNA

NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818

G

fibroblast growth factor 21

increases expression

Diquat results in increased expression of FGF21 mRNA

NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454

G

fibroblast growth factor binding protein 1

increases expression

Diquat results in increased expression of FGFBP1 mRNA

NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496

G

fibrinogen gamma chain

increases expression

Diquat results in increased expression of FGG mRNA

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

G

fibrinogen-like 2

decreases expression

Diquat results in decreased expression of FGL2 mRNA

NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207

G

FHF complex subunit HOOK interacting protein 1B

decreases expression

Diquat results in decreased expression of FHIP1B protein

NCBI chr 1:159,718,679...159,748,449
Ensembl chr 1:159,726,004...159,748,408

G

four and a half LIM domains 2

decreases expression

Diquat results in decreased expression of FHL2 mRNA

NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192

G

fat storage-inducing transmembrane protein 1

increases expression

Diquat results in increased expression of FITM1 mRNA

NCBI chr15:29,064,746...29,066,015
Ensembl chr15:29,064,707...29,066,015

G

FKBP prolyl isomerase 5

increases expression

Diquat results in increased expression of FKBP5 mRNA

NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674

G

Fms related receptor tyrosine kinase 4

decreases expression

Diquat results in decreased expression of FLT4 mRNA

NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770

G

fibronectin 1

decreases expression

Diquat results in decreased expression of FN1 mRNA

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

fructosamine 3 kinase

decreases expression

Diquat results in decreased expression of FN3K protein

NCBI chr10:106,700,670...106,715,903
Ensembl chr10:106,700,670...106,715,895

G

fibronectin type III domain containing 1

decreases expression

Diquat results in decreased expression of FNDC1 mRNA

NCBI chr 1:47,281,839...47,364,247
Ensembl chr 1:47,281,844...47,364,259

G

folate receptor alpha

increases expression

Diquat results in increased expression of FOLR1 protein

NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

Diquat results in increased expression of FOS mRNA
PROP1 protein affects the reaction [Diquat results in increased expression of FOS mRNA]

PMID:20826540 PMID:36851058

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

FOS like 1, AP-1 transcription factor subunit

increases expression

Diquat results in increased expression of FOSL1 mRNA

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

G

forkhead box M1

decreases expression

Diquat results in decreased expression of FOXM1 mRNA

NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684

G

forkhead box O1

increases expression
multiple interactions

Diquat results in increased expression of FOXO1 mRNA
procyanidin B2 inhibits the reaction [Diquat results in increased expression of FOXO1 mRNA]

NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790

G

FRA10A associated CGG repeat 1

decreases expression

Diquat results in decreased expression of FRA10AC1 protein

NCBI chr 1:235,969,071...236,001,074
Ensembl chr 1:235,969,112...236,001,210

G

Fras1 related extracellular matrix 1

decreases expression

Diquat results in decreased expression of FREM1 mRNA

NCBI chr 5:97,321,266...97,469,523
Ensembl chr 5:97,322,538...97,469,543

G

FERM domain containing 6

decreases expression

Diquat results in decreased expression of FRMD6 mRNA; Diquat results in decreased expression of FRMD6 protein

NCBI chr 6:89,345,983...89,419,579
Ensembl chr 6:89,346,035...89,419,579

G

FERM domain containing 8

decreases expression

Diquat results in decreased expression of FRMD8 protein

NCBI chr 1:203,143,216...203,163,868
Ensembl chr 1:203,143,218...203,163,870

G

FERM and PDZ domain containing 3

decreases expression

Diquat results in decreased expression of FRMPD3 mRNA

NCBI chr X:103,964,168...104,113,864
Ensembl chr X:104,043,194...104,111,968

G

frizzled-related protein

decreases expression

Diquat results in decreased expression of FRZB mRNA

NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208

G

fascin actin-bundling protein 1

decreases expression

Diquat results in decreased expression of FSCN1 mRNA

NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211

G

fibronectin type III and SPRY domain containing 1-like

decreases expression

Diquat results in decreased expression of FSD1L mRNA

NCBI chr 5:68,258,877...68,334,931
Ensembl chr 5:68,258,932...68,334,928

G

formimidoyltransferase cyclodeaminase

increases expression

Diquat results in increased expression of FTCD mRNA

NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735

G

ferritin heavy chain 1

increases expression
decreases expression
multiple interactions

Diquat results in increased expression of FTH1 mRNA
Diquat results in decreased expression of FTH1 protein
Chloroquine inhibits the reaction [Diquat results in decreased expression of and results in increased degradation of FTH1 protein]; Diquat results in decreased expression of and results in increased degradation of FTH1 protein; FTH1 protein promotes the reaction [Diquat results in increased cleavage of GSDME protein]; MAP1LC3B protein promotes the reaction [Diquat results in decreased expression of and results in increased degradation of FTH1 protein]; MAP1LC3B protein promotes the reaction [Diquat results in decreased expression of FTH1 protein]

PMID:21698372 PMID:36851058 PMID:38128689

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

ferritin light chain 1

increases expression
decreases expression

Diquat results in increased expression of FTL1 mRNA
Diquat results in decreased expression of FTL protein

PMID:16962985 PMID:36851058 PMID:38128689

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725

G

fucose mutarotase

decreases expression

Diquat results in decreased expression of FUOM protein

NCBI chr 1:194,888,535...194,893,046
Ensembl chr 1:194,886,709...194,893,046

G

FXYD domain-containing ion transport regulator 2

decreases expression

Diquat results in decreased expression of FXYD2 protein

NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203

G

FYN binding protein 1

decreases expression

Diquat results in decreased expression of FYB1 mRNA

NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629

G

G0/G1switch 2

increases expression

Diquat results in increased expression of G0S2 mRNA

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

glucose-6-phosphate dehydrogenase

increases expression
increases activity

Diquat results in increased expression of G6PD mRNA; Diquat results in increased expression of G6PD protein
Diquat results in increased activity of G6PD protein
Diquat results in increased expression of G6PDX mRNA

PMID:8934631 PMID:28108222 PMID:36851058

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

gamma-aminobutyric acid type A receptor subunit alpha 3

decreases expression

Diquat results in decreased expression of GABRA3 mRNA

NCBI chr X:150,244,745...150,501,566
Ensembl chr X:150,261,607...150,501,559

G

gamma-aminobutyric acid type A receptor subunit beta 3

decreases expression

Diquat results in decreased expression of GABRB3 mRNA

NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961

G

growth arrest and DNA-damage-inducible, alpha

increases expression

Diquat results in increased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

guanidinoacetate N-methyltransferase

decreases expression

Diquat results in decreased expression of GAMT protein

NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778

G

golgi associated kinase 1B

decreases expression

Diquat results in decreased expression of GASK1B mRNA

NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477

G

glycine amidinotransferase

decreases expression

Diquat results in decreased expression of GATM mRNA

NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129

G

glucosylceramidase beta 2

decreases expression

Diquat results in decreased expression of GBA2 protein

NCBI chr 5:57,822,389...57,834,522
Ensembl chr 5:57,822,389...57,834,072

G

guanylate binding protein 2

decreases expression

Diquat results in decreased expression of GBP2 mRNA

NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571

G

guanylate binding protein 4

decreases expression

Diquat results in decreased expression of GBP3 mRNA; Diquat results in decreased expression of GBP4 mRNA

NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879

G

guanylate binding protein 5

decreases expression

Diquat results in decreased expression of GBP5 mRNA; Diquat results in decreased expression of GBP5 protein

NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061

G

guanylate binding protein family member 6

decreases expression

Diquat results in decreased expression of GBP6 mRNA; Diquat results in decreased expression of GBP9 mRNA

NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,730,453...4,839,062
Ensembl chr14:4,730,453...4,839,062

G

GC, vitamin D binding protein

increases expression

Diquat results in increased expression of GC mRNA

NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567

G

grancalcin

decreases expression

Diquat results in decreased expression of GCA protein

NCBI chr 3:47,297,320...47,329,913
Ensembl chr 3:47,297,383...47,328,581

G

glutamate-cysteine ligase, catalytic subunit

increases expression
decreases expression
decreases activity
multiple interactions

Diquat results in increased expression of GCLC mRNA
Diquat results in decreased expression of GCLC mRNA
Diquat results in decreased activity of GCLC protein
[KEAP1 gene mutant form inhibits the reaction [Diquat results in decreased abundance of Glutathione]] which results in increased expression of GCLC mRNA
Diquat results in increased expression of GCLC protein

PMID:7676460 PMID:16962985 PMID:22762311 PMID:38128689

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

increases expression

Diquat results in increased expression of GCLM mRNA; Diquat results in increased expression of GCLM protein

PMID:16962985 PMID:20826540 PMID:21172416 PMID:38128689

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

growth differentiation factor 15

increases expression

Diquat results in increased expression of GDF15 mRNA

NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055

G

Gfo/Idh/MocA-like oxidoreductase domain containing 2

increases expression

Diquat results in increased expression of GFOD2 protein

NCBI chr19:33,599,689...33,647,060
Ensembl chr19:33,604,187...33,647,004

G

golgi associated, gamma adaptin ear containing, ARF binding protein 1

increases expression

Diquat results in increased expression of GGA1 protein

NCBI chr 7:110,436,071...110,451,790
Ensembl chr 7:110,435,062...110,451,789

G

gamma-glutamyl cyclotransferase

decreases expression

Diquat results in decreased expression of GGCT mRNA

NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277

G

gamma-glutamyl transferase 6

increases expression

Diquat results in increased expression of GGT6 mRNA

NCBI chr10:57,051,977...57,054,900
Ensembl chr10:57,051,825...57,067,260

G

GTPase, IMAP family member 6

decreases expression

Diquat results in decreased expression of GIMAP6 mRNA

NCBI chr 4:77,653,703...77,659,112
Ensembl chr 4:77,652,610...77,659,116

G

gap junction protein, alpha 1

decreases expression

Diquat results in decreased expression of GJA1 mRNA

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

G

gap junction protein, beta 1

increases expression

Diquat results in increased expression of GJB1 mRNA; Diquat results in increased expression of GJB1 protein

NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925

G

glycine decarboxylase

increases expression

Diquat results in increased expression of GLDC mRNA

NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097

G

glutaredoxin

increases response to substance
increases expression

GLRX gene mutant form results in increased susceptibility to Diquat
Diquat results in increased expression of GLRX mRNA

PMID:17893043 PMID:36851058

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

glutaredoxin 5

increases expression

Diquat results in increased expression of GLRX5 mRNA

NCBI chr 6:123,988,461...123,998,545
Ensembl chr 6:123,988,134...123,998,545

G

glutamate dehydrogenase 1

increases expression

Diquat results in increased expression of GLUD1 mRNA

NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957

G

G protein subunit alpha transducin 1

increases expression

Diquat results in increased expression of GNAT1 mRNA

NCBI chr 8:108,350,935...108,355,671
Ensembl chr 8:108,350,935...108,355,671

G

G protein subunit gamma 2

decreases expression

Diquat results in decreased expression of GNG2 mRNA

NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,316,059...4,417,183

G

G protein nucleolar 3

increases expression

Diquat results in increased expression of GNL3 protein

NCBI chr16:6,207,402...6,213,491
Ensembl chr16:6,207,402...6,213,392

G

glycine N-methyltransferase

increases expression

Diquat results in increased expression of GNMT mRNA

NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434

G

G patch domain containing 11

decreases expression

Diquat results in decreased expression of GPATCH11 protein

NCBI chr 6:16,229,933...16,243,305
Ensembl chr 6:16,233,059...16,243,238

G

glypican 4

decreases expression

Diquat results in decreased expression of GPC4 protein

NCBI chr X:131,644,711...131,755,349
Ensembl chr X:131,644,704...131,755,284

G

glycerol-3-phosphate dehydrogenase 1

increases expression

Diquat results in increased expression of GPD1 mRNA

NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529

G

glycoprotein m6a

decreases expression

Diquat results in decreased expression of GPM6A mRNA

NCBI chr16:36,641,282...36,973,377
Ensembl chr16:36,641,284...36,973,475

G

glycoprotein m6b

decreases expression

Diquat results in decreased expression of GPM6B mRNA

NCBI chr X:28,057,788...28,204,409
Ensembl chr X:28,059,450...28,204,211

G

G protein-coupled receptor 132

decreases expression

Diquat results in decreased expression of GPR132 mRNA

NCBI chr 6:131,924,061...131,943,327
Ensembl chr 6:131,924,160...131,942,168

G

G protein-coupled receptor 135

increases expression

Diquat results in increased expression of GPR135 mRNA

NCBI chr 6:90,627,533...90,630,661
Ensembl chr 6:90,629,178...90,630,551

G

G protein-coupled receptor 183

decreases expression

Diquat results in decreased expression of GPR183 mRNA

NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559

G

G-protein coupled receptor 65

decreases expression

Diquat results in decreased expression of GPR65 mRNA

NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512

G

glutamic--pyruvic transaminase

multiple interactions
increases activity
increases expression

GPX4 protein inhibits the reaction [Diquat results in increased activity of GPT protein]
Diquat results in increased expression of GPT mRNA; Diquat results in increased expression of GPT protein
Ascorbic Acid inhibits the reaction [Diquat results in increased expression of GPT protein]; Ellagic Acid inhibits the reaction [Diquat results in increased activity of GPT protein]

PMID:15496407 PMID:33475796 PMID:35268077 PMID:36851058

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutamic--pyruvic transaminase 2

decreases expression

Diquat results in decreased expression of GPT2 protein

NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610

G

glutathione peroxidase 1

decreases expression
increases response to substance
multiple interactions
affects response to substance
decreases response to substance

Diquat results in decreased expression of GPX1 mRNA; Diquat results in decreased expression of GPX1 protein
GPX1 gene mutant form results in increased susceptibility to Diquat; GPX1 protein results in increased susceptibility to Diquat
Ellagic Acid inhibits the reaction [Diquat results in decreased expression of GPX1 mRNA]; GPX1 protein affects the reaction [Diquat results in decreased activity of SOD1 protein]; GPX1 protein affects the reaction [Diquat results in increased abundance of F2-Isoprostanes]; GPX1 protein affects the reaction [Diquat results in increased activity of SOD2 protein]; GPX1 protein affects the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in decreased activity of SOD1 protein]]; GPX1 protein affects the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in increased activity of SOD2 protein]]; GPX1 protein affects the susceptibility to [Diquat co-treated with S-Nitroso-N-Acetylpenicillamine]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in decreased expression of GPX1 protein]
GPX1 protein affects the susceptibility to Diquat
GPX1 protein results in decreased susceptibility to Diquat

PMID:10490281 PMID:11568445 PMID:11672444 PMID:15182862 PMID:35268077

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

multiple interactions
decreases expression

[3,4-dihydroxyphenylethanol co-treated with Diquat] results in decreased expression of GPX2 mRNA
Diquat results in decreased expression of GPX2 mRNA

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutathione peroxidase 4

decreases response to substance
multiple interactions
increases expression

GPX4 protein alternative form results in decreased susceptibility to Diquat
GPX4 protein inhibits the reaction [Diquat results in increased activity of GPT protein]; GPX4 protein inhibits the reaction [Diquat results in increased cleavage of CASP3 protein]
Diquat results in increased expression of GPX4 mRNA

PMID:15496407 PMID:16962985 PMID:19744930

NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982

G

glutamate ionotropic receptor NMDA type subunit associated protein 1

increases expression

Diquat results in increased expression of GRINA mRNA

NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366

G

granulin precursor

increases expression

Diquat results in increased expression of GRN protein

NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775

G

GrpE-like 2, mitochondrial

decreases expression

Diquat results in decreased expression of GRPEL2 protein

NCBI chr18:55,167,831...55,180,073
Ensembl chr18:55,168,209...55,180,180

G

gastrin releasing peptide receptor

decreases expression

Diquat results in decreased expression of GRPR protein

NCBI chr X:30,998,425...31,038,442
Ensembl chr X:30,998,416...31,038,442

G

gamma-secretase activating protein

decreases expression

Diquat results in decreased expression of GSAP mRNA

NCBI chr 4:13,813,046...13,907,875
Ensembl chr 4:13,813,046...13,907,814

G

gasdermin D

decreases expression

Diquat results in decreased expression of GSDMD protein

NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055

G

gasdermin E

multiple interactions
increases cleavage

Deferoxamine inhibits the reaction [Diquat results in increased cleavage of GSDME protein]; FTH1 protein promotes the reaction [Diquat results in increased cleavage of GSDME protein]; Glutathione inhibits the reaction [Diquat results in increased cleavage of GSDME protein]

NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806

G

glutathione-disulfide reductase

increases expression

Diquat results in increased expression of GSR mRNA

PMID:16962985 PMID:36851058

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione synthetase

increases expression

Diquat results in increased expression of GSS protein

NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198

G

glutathione S-transferase alpha 1

decreases expression

Diquat results in decreased expression of GSTA1 mRNA

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 2

decreases expression

Diquat results in decreased expression of GSTA2 mRNA

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 3

decreases expression

Diquat results in decreased expression of GSTA3 mRNA

NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240

G

glutathione S-transferase alpha 5

increases expression

Diquat results in increased expression of GSTA5 mRNA

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 1

decreases expression
increases expression

Diquat results in decreased expression of GSTM1 mRNA
Diquat results in increased expression of GSTM1 mRNA

PMID:7676460 PMID:36851058

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase mu 2

decreases expression

Diquat results in decreased expression of GSTM2 mRNA

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase mu 4

increases expression

Diquat results in increased expression of GSTM4 mRNA

NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323

G

glutathione S-transferase, mu 5

increases expression

Diquat results in increased expression of GSTM3 mRNA

NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553

G

glutathione S-transferase pi 1

increases expression

Diquat results in increased expression of GSTP1 mRNA

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase pi 3

increases expression

Diquat results in increased expression of GSTP3 mRNA

NCBI chr 1:201,355,682...201,358,216
Ensembl chr 1:201,355,682...201,358,330

G

guanylate cyclase activator 2B

increases expression

Diquat results in increased expression of GUCA2B mRNA

NCBI chr 5:133,246,891...133,248,941
Ensembl chr 5:133,246,909...133,248,966

G

glycophorin C

decreases expression

Diquat results in decreased expression of GYPC protein

NCBI chr18:24,160,738...24,193,408
Ensembl chr18:24,160,739...24,193,204

G

3-hydroxyacyl-CoA dehydratase 1

increases expression

Diquat results in increased expression of HACD1 mRNA

NCBI chr17:77,081,508...77,106,114
Ensembl chr17:77,083,740...77,106,073

G

2-hydroxyacyl-CoA lyase 1

increases expression

Diquat results in increased expression of HACL1 mRNA

NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027

G

hepcidin antimicrobial peptide

increases expression

Diquat results in increased expression of HAMP mRNA
Diquat results in increased expression of HAMP protein

PMID:21698372 PMID:36851058

NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891

G

hyaluronan and proteoglycan link protein 1

decreases expression

Diquat results in decreased expression of HAPLN1 mRNA

NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777

G

hepatitis A virus cellular receptor 2

decreases expression

Diquat results in decreased expression of HAVCR2 mRNA

NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137

G

hydroxycarboxylic acid receptor 1

decreases expression

Diquat results in decreased expression of HCAR1 mRNA

NCBI chr12:32,710,680...32,713,934
Ensembl chr12:32,711,027...32,712,082

G

HEAT repeat containing 3

decreases expression

Diquat results in decreased expression of HEATR3 protein

NCBI chr19:18,892,477...18,930,502
Ensembl chr19:18,893,144...18,930,509

G

heme binding protein 1

increases expression

Diquat results in increased expression of HEBP1 protein

NCBI chr 4:167,974,316...168,003,854
Ensembl chr 4:167,974,319...168,003,854

G

HEN methyltransferase 1

decreases expression

Diquat results in decreased expression of HENMT1 mRNA

NCBI chr 2:196,585,732...196,603,700
Ensembl chr 2:196,586,797...196,599,738

G

homeostatic iron regulator

increases expression

Diquat results in increased expression of HFE mRNA

NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502

G

hepatocyte growth factor

decreases expression

Diquat results in decreased expression of HGF mRNA

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

G

heparan-alpha-glucosaminide N-acetyltransferase

decreases expression

Diquat results in decreased expression of HGSNAT protein

NCBI chr16:66,105,233...66,137,444
Ensembl chr16:66,105,181...66,136,138

G

HIC ZBTB transcriptional repressor 1

decreases expression

Diquat results in decreased expression of HIC1 mRNA

NCBI chr10:60,014,520...60,019,475
Ensembl chr10:60,011,528...60,019,475

G

HID1 domain containing

decreases expression

Diquat results in decreased expression of HID1 protein

NCBI chr10:100,589,555...100,610,050
Ensembl chr10:100,589,555...100,610,041

G

hypoxia inducible factor 3 subunit alpha

increases expression

Diquat results in increased expression of HIF3A mRNA

NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758

G

hemicentin 1

decreases expression

Diquat results in decreased expression of HMCN1 mRNA

NCBI chr13:62,615,461...63,084,524
Ensembl chr13:62,615,461...63,084,524

G

high mobility group AT-hook 1

increases expression

Diquat results in increased expression of HMGA1 mRNA

NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752

G

high mobility group box 1

increases expression
multiple interactions

Diquat results in increased expression of HMGB1 mRNA; Diquat results in increased expression of HMGB1 protein
Diquat results in increased expression of and results in increased secretion of HMGB1 protein; THBD protein modified form inhibits the reaction [Diquat results in increased expression of and results in increased secretion of HMGB1 protein]; THBD protein modified form inhibits the reaction [Diquat results in increased expression of HMGB1 mRNA]

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

G

high mobility group box 3

increases expression

Diquat results in increased expression of HMGB3 protein

NCBI chr X:149,296,303...149,301,290
Ensembl chr X:149,296,375...149,301,292

G

3-hydroxy-3-methylglutaryl-CoA reductase

decreases expression

Diquat results in decreased expression of HMGCR mRNA

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

increases expression

Diquat results in increased expression of HMGCS2 mRNA; Diquat results in increased expression of HMGCS2 protein

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

heme oxygenase 1

increases expression
multiple interactions
increases activity
decreases expression

Diquat results in increased expression of HMOX1 mRNA; Diquat results in increased expression of HMOX1 protein
Ascorbic Acid inhibits the reaction [Diquat results in decreased expression of HMOX1 protein]; Ellagic Acid inhibits the reaction [Diquat results in decreased expression of HMOX1 mRNA]; PROP1 protein affects the reaction [Diquat results in increased expression of HMOX1 mRNA]
Diquat results in increased activity of HMOX1 protein
Diquat results in decreased expression of HMOX1 mRNA; Diquat results in decreased expression of HMOX1 protein

PMID:20826540 PMID:21172416 PMID:33475796 PMID:35268077 PMID:36851058 More...

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

HNF1 homeobox B

decreases expression

Diquat results in decreased expression of HNF1B protein

NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888

G

heterogeneous nuclear ribonucleoprotein D-like

increases expression

Diquat results in increased expression of HNRNPDL protein

NCBI chr14:9,557,430...9,563,659
Ensembl chr14:9,557,425...9,562,506

G

hippocalcin-like 1

increases expression

Diquat results in increased expression of HPCAL1 mRNA

NCBI chr 6:40,478,206...40,584,721
Ensembl chr 6:40,478,208...40,584,687

G

4-hydroxyphenylpyruvate dioxygenase

increases expression

Diquat results in increased expression of HPD mRNA

NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766

G

4-hydroxyphenylpyruvate dioxygenase-like

increases expression

Diquat results in increased expression of HPDL mRNA

NCBI chr 5:130,286,627...130,288,233
Ensembl chr 5:130,286,631...130,288,233

G

homologous recombination factor with OB-fold

decreases expression

Diquat results in decreased expression of HROB mRNA

NCBI chr10:87,206,017...87,222,483
Ensembl chr10:87,206,049...87,222,483

G

heparan sulfate 6-O-sulfotransferase 2

decreases expression

Diquat results in decreased expression of HS6ST2 mRNA

NCBI chr X:130,966,547...131,261,629
Ensembl chr X:130,968,385...131,261,492

G

hydroxysteroid (17-beta) dehydrogenase 2

decreases expression

Diquat results in decreased expression of HSD17B2 protein

NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

decreases expression

Diquat results in decreased expression of HSD3B2 mRNA

NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999

G

heat shock transcription factor 2 binding protein

decreases expression

Diquat results in decreased expression of HSF2BP mRNA

NCBI chr20:10,035,562...10,123,059
Ensembl chr20:10,035,562...10,121,242

G

heat shock protein family A (Hsp70) member 1A

increases expression

Diquat results in increased expression of HSPA1A mRNA

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family A (Hsp70) member 1B

increases expression

Diquat results in increased expression of HSPA1B mRNA

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family A (Hsp70) member 6 like, pseudogene 1

increases expression

Diquat results in increased expression of HSPA6 mRNA

NCBI chr13:83,273,176...83,274,317

G

heat shock protein family B (small) member 6

increases expression

Diquat results in increased expression of HSPB6 mRNA

NCBI chr 1:85,806,898...85,809,072
Ensembl chr 1:85,806,146...85,809,071

G

heat shock protein family B (small) member 8

increases expression

Diquat results in increased expression of HSPB8 mRNA

NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185

G

HIV-1 Tat interactive protein 2

increases expression

Diquat results in increased expression of HTATIP2 mRNA

NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629

G

hyaluronidase 1

increases expression

Diquat results in increased expression of HYAL1 mRNA

NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210

G

intercellular adhesion molecule 1

increases expression

Diquat results in increased expression of ICAM1 mRNA

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

inhibitor of DNA binding 1

increases expression

Diquat results in increased expression of ID1 mRNA

NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419

G

inhibitor of DNA binding 3

increases expression

Diquat results in increased expression of ID3 mRNA

NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349

G

isopentenyl-diphosphate delta isomerase 1

decreases expression

Diquat results in decreased expression of IDI1 mRNA

NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357

G

immediate early response 5-like

increases expression

Diquat results in increased expression of IER5L mRNA

NCBI chr 3:13,744,056...13,745,647
Ensembl chr 3:13,744,078...13,745,647

G

interferon-induced protein with tetratricopeptide repeats 3

decreases expression

Diquat results in decreased expression of IFIT3 mRNA

NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307

G

interferon induced transmembrane protein 10

increases expression

Diquat results in increased expression of IFITM10 mRNA

NCBI chr 1:197,507,501...197,524,180
Ensembl chr 1:197,507,503...197,525,151

G

interferon gamma

multiple interactions

Diquat promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased metabolism of Nitric Oxide]

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interferon-related developmental regulator 1

increases expression

Diquat results in increased expression of IFRD1 mRNA

NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990

G

intraflagellar transport 27

decreases expression

Diquat results in decreased expression of IFT27 protein

NCBI chr 7:109,738,622...109,754,416
Ensembl chr 7:109,738,622...109,754,416

G

insulin-like growth factor 1

decreases expression

Diquat results in decreased expression of IGF1 mRNA

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor 1 receptor

increases response to substance

IGF1R protein results in increased susceptibility to Diquat

NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777

G

insulin-like growth factor 2 mRNA binding protein 2

increases expression

Diquat results in increased expression of IGF2BP2 mRNA

NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377

G

insulin-like growth factor binding protein, acid labile subunit

increases expression

Diquat results in increased expression of IGFALS mRNA

NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677

G

insulin-like growth factor binding protein 3

decreases expression

Diquat results in decreased expression of IGFBP3 mRNA

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

insulin-like growth factor binding protein 5

decreases expression

Diquat results in decreased expression of IGFBP5 mRNA

NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156

G

immunoglobulin superfamily, member 10

decreases expression

Diquat results in decreased expression of IGSF10 mRNA

NCBI chr 2:143,575,710...143,605,044
Ensembl chr 2:143,576,070...143,604,773

G

IKAROS family zinc finger 1

decreases expression

Diquat results in decreased expression of IKZF1 mRNA

NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416

G

interleukin 10 receptor subunit alpha

decreases expression

Diquat results in decreased expression of IL10RA mRNA

NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061

G

interleukin 16

decreases expression

Diquat results in decreased expression of IL16 mRNA

NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130

G

interleukin 1 beta

decreases expression
increases expression
increases secretion
multiple interactions

Diquat results in decreased expression of IL1B mRNA
Diquat results in increased expression of IL1B protein
Diquat results in increased secretion of IL1B protein
THBD protein modified form inhibits the reaction [Diquat results in increased secretion of IL1B protein]

PMID:36572071 PMID:37277018

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 21 receptor

decreases expression

Diquat results in decreased expression of IL21R mRNA

NCBI chr 1:180,168,028...180,195,690
Ensembl chr 1:180,168,097...180,195,522

G

interleukin 6

increases expression

Diquat results in increased expression of IL6 protein

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

IMP U3 small nucleolar ribonucleoprotein 4

decreases expression

Diquat results in decreased expression of IMP4 protein

NCBI chr 9:36,654,127...36,659,265
Ensembl chr 9:36,654,401...36,660,075

G

innate immunity activator

increases expression

Diquat results in increased expression of INAVA mRNA

NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729

G

indolethylamine N-methyltransferase

decreases expression

Diquat results in decreased expression of INMT mRNA

NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493

G

inositol polyphosphate-4-phosphatase type II B

decreases expression

Diquat results in decreased expression of INPP4B mRNA

NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634

G

inositol polyphosphate-5-phosphatase A

increases expression

Diquat results in increased expression of INPP5A mRNA

NCBI chr 1:194,190,086...194,380,429
Ensembl chr 1:194,190,393...194,380,428

G

IQ motif and ankyrin repeat containing 1

decreases expression

Diquat results in decreased expression of IQANK1 protein

NCBI chr 7:107,724,962...107,759,163
Ensembl chr 7:107,724,997...107,759,162

G

inositol 1,4,5-triphosphate receptor associated 1

increases expression

Diquat results in increased expression of IRAG1 protein

NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176

G

interferon regulatory factor 5

decreases expression

Diquat results in decreased expression of IRF5 mRNA

NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267

G

interferon regulatory factor 7

decreases expression

Diquat results in decreased expression of IRF7 mRNA

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

G

immunoglobulin superfamily containing leucine-rich repeat

decreases expression

Diquat results in decreased expression of ISLR mRNA

NCBI chr 8:58,571,155...58,574,128
Ensembl chr 8:58,570,777...58,574,130

G

integrin subunit alpha 7

increases expression

Diquat results in increased expression of ITGA7 mRNA

NCBI chr 7:1,360,125...1,388,886
Ensembl chr 7:1,359,940...1,388,450

G

integrin subunit alpha 8

decreases expression

Diquat results in decreased expression of ITGA8 mRNA

NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510

G

integrin subunit alpha 9

decreases expression

Diquat results in decreased expression of ITGA9 mRNA

NCBI chr 8:118,307,424...118,615,527
Ensembl chr 8:118,307,381...118,613,754

G

integrin subunit alpha L

decreases expression

Diquat results in decreased expression of ITGAL mRNA

NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732

G

integrin subunit alpha X

decreases expression

Diquat results in decreased expression of ITGAX mRNA

NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698

G

inter-alpha-trypsin inhibitor heavy chain 2

decreases expression

Diquat results in decreased expression of ITIH2 mRNA

NCBI chr17:68,375,574...68,411,849
Ensembl chr17:68,375,567...68,411,841

G

inter-alpha trypsin inhibitor, heavy chain 3

increases expression

Diquat results in increased expression of ITIH3 mRNA; Diquat results in increased expression of ITIH3 protein

NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924

G

ITPRIP like 2

decreases expression

Diquat results in decreased expression of ITPRIPL2 mRNA

NCBI chr 1:172,801,152...172,803,047
Ensembl chr 1:172,796,849...172,802,950

G

jagunal homolog 1

decreases expression

Diquat results in decreased expression of JAGN1 protein

NCBI chr 4:146,591,577...146,596,287
Ensembl chr 4:146,591,510...146,596,288

G

Janus kinase 2

increases expression

Diquat results in increased expression of JAK2 protein

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

G

joining chain of multimeric IgA and IgM

decreases expression

Diquat results in decreased expression of JCHAIN mRNA

NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298

G

jumping translocation breakpoint

increases expression

Diquat results in increased expression of JTB protein

NCBI chr 2:175,685,392...175,689,609
Ensembl chr 2:175,684,993...175,690,108

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

Diquat results in increased expression of JUN mRNA

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

JunB proto-oncogene, AP-1 transcription factor subunit

increases expression

Diquat results in increased expression of JUNB mRNA

NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035

G

potassium voltage-gated channel subfamily E regulatory subunit 4

decreases expression

Diquat results in decreased expression of KCNE4 mRNA

NCBI chr 9:80,243,429...80,251,533
Ensembl chr 9:80,247,379...80,250,979

G

potassium voltage-gated channel modifier subfamily G member 1

decreases expression

Diquat results in decreased expression of KCNG1 mRNA

NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:156,973,156...156,992,635

G

potassium voltage-gated channel interacting protein 2

increases expression

Diquat results in increased expression of KCNIP2 mRNA

NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874

G

potassium inwardly-rectifying channel, subfamily J, member 8

decreases expression

Diquat results in decreased expression of KCNJ8 mRNA

NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603

G

potassium two pore domain channel subfamily K member 2

decreases expression

Diquat results in decreased expression of KCNK2 mRNA

NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435

G

potassium sodium-activated channel subfamily T member 2

decreases expression

Diquat results in decreased expression of KCNT2 mRNA

NCBI chr13:51,664,129...52,059,209
Ensembl chr13:51,664,686...52,056,987

G

potassium channel tetramerization domain containing 1

increases expression

Diquat results in increased expression of KCTD1 mRNA

NCBI chr18:6,122,390...6,316,434
Ensembl chr18:6,122,390...6,317,393

G

potassium channel tetramerization domain containing 10

increases expression

Diquat results in increased expression of KCTD10 protein

NCBI chr12:42,230,159...42,248,792
Ensembl chr12:42,230,269...42,248,783

G

KDEL endoplasmic reticulum protein retention receptor 1

decreases expression

Diquat results in decreased expression of KDELR1 protein

NCBI chr 1:96,347,258...96,358,145
Ensembl chr 1:96,347,150...96,358,157

G

KDEL endoplasmic reticulum protein retention receptor 3

decreases expression

Diquat results in decreased expression of KDELR3 mRNA

NCBI chr 7:111,079,236...111,089,463
Ensembl chr 7:111,079,218...111,101,600

G

kinase insert domain receptor

decreases expression

Diquat results in decreased expression of KDR mRNA

NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018

G

Kelch-like ECH-associated protein 1

multiple interactions
decreases expression

[KEAP1 gene mutant form inhibits the reaction [Diquat results in decreased abundance of Glutathione]] which results in increased expression of GCLC mRNA; KEAP1 gene mutant form inhibits the reaction [Diquat results in decreased abundance of Glutathione]; KEAP1 gene mutant form inhibits the reaction [NFE2L2 gene mutant form results in increased susceptibility to Diquat]
Diquat results in decreased expression of KEAP1 protein

PMID:22762311 PMID:36851058

NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862

G

KH domain containing 4, pre-mRNA splicing factor

decreases expression

Diquat results in decreased expression of KHDC4 protein

NCBI chr 2:174,149,059...174,177,816
Ensembl chr 2:174,149,141...174,177,504

G

kinesin family member 11

decreases expression

Diquat results in decreased expression of KIF11 mRNA

NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766

G

kinesin family member 20B

decreases expression

Diquat results in decreased expression of KIF20B mRNA

NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787

G

kinesin family member 4A

increases expression

Diquat results in increased expression of KIF4 protein

NCBI chr X:65,721,746...65,824,277
Ensembl chr X:65,721,779...65,824,139

G

kinesin family member 5A

increases expression

Diquat results in increased expression of KIF5A mRNA

NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858

G

kinesin family member C3

decreases expression

Diquat results in decreased expression of KIFC3 protein

NCBI chr19:9,825,114...9,920,371
Ensembl chr19:9,886,693...9,920,451

G

Klotho

decreases expression

Diquat results in decreased expression of KL protein

NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080

G

keratin 18

increases expression

Diquat results in increased expression of KRT18 mRNA

NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166

G

keratin 20

increases expression

Diquat results in increased expression of KRT20 mRNA

NCBI chr10:84,384,790...84,394,125
Ensembl chr10:84,384,802...84,394,107

G

keratin 8

increases expression

Diquat results in increased expression of KRT8 mRNA

NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728

G

kynureninase

increases expression

Diquat results in increased expression of KYNU mRNA

PMID:21172416 PMID:36851058

NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488

G

laminin subunit alpha 2

decreases expression

Diquat results in decreased expression of LAMA2 mRNA

NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530

G

laminin subunit alpha 4

decreases expression

Diquat results in decreased expression of LAMA4 mRNA

NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347

G

laminin subunit gamma 3

decreases expression

Diquat results in decreased expression of LAMC3 protein

NCBI chr 3:15,165,220...15,226,697
Ensembl chr 3:15,165,220...15,226,697

G

lysosomal protein transmembrane 5

decreases expression

Diquat results in decreased expression of LAPTM5 mRNA

NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807

G

LAS1-like, ribosome biogenesis factor

decreases expression

Diquat results in decreased expression of LAS1L protein

NCBI chr X:60,851,969...60,873,717
Ensembl chr X:60,851,962...60,873,687

G

lipocalin 2

increases expression

Diquat results in increased expression of LCN2 mRNA

NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095

G

LIM domain binding 2

decreases expression

Diquat results in decreased expression of LDB2 mRNA

NCBI chr14:66,277,044...66,598,071
Ensembl chr14:66,277,085...66,597,778

G

leucine decarboxylase 1

decreases expression

Diquat results in decreased expression of LDC1 mRNA

NCBI chr 5:142,551,120...142,563,217
Ensembl chr 5:142,552,008...142,563,074

G

leptin receptor

decreases expression

Diquat results in decreased expression of LEPR mRNA

NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908

G

galectin 3

increases expression

Diquat results in increased expression of LGALS3 mRNA

NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025

G

galectin 4

increases expression

Diquat results in increased expression of LGALS4 mRNA

NCBI chr 1:84,124,766...84,132,481
Ensembl chr 1:84,124,764...84,132,481

G

galectin 8

decreases expression

Diquat results in decreased expression of LGALS8 protein

NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764

G

galectin-like

increases expression

Diquat results in increased expression of LGALSL protein

NCBI chr14:94,996,991...95,004,499
Ensembl chr14:94,996,990...95,004,980

G

leucine-rich repeat LGI family, member 2

increases expression

Diquat results in increased expression of LGI2 mRNA

NCBI chr14:58,415,965...58,443,450
Ensembl chr14:58,415,965...58,443,407

G

leucine-rich repeat LGI family, member 3

decreases expression

Diquat results in decreased expression of LGI3 mRNA

NCBI chr15:45,605,611...45,612,739
Ensembl chr15:45,605,611...45,612,739

G

LHFPL tetraspan subfamily member 6

decreases expression

Diquat results in decreased expression of LHFPL6 mRNA

NCBI chr 2:137,126,485...137,324,442
Ensembl chr 2:137,126,509...137,324,443

G

lipoic acid synthetase

decreases expression

Diquat results in decreased expression of LIAS protein

NCBI chr14:42,876,699...42,893,824
Ensembl chr14:42,876,699...42,893,783

G

LIF, interleukin 6 family cytokine

increases expression

Diquat results in increased expression of LIF mRNA

NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482

G

LIM domain only 2

decreases expression

Diquat results in decreased expression of LMO2 mRNA

NCBI chr 3:90,355,234...90,377,970
Ensembl chr 3:90,365,883...90,377,953

G

LON peptidase N-terminal domain and ring finger 3

increases expression

Diquat results in increased expression of LONRF3 mRNA

NCBI chr X:115,565,214...115,603,886
Ensembl chr X:115,565,267...115,598,809

G

lysophosphatidic acid receptor 2

increases expression

Diquat results in increased expression of LPAR2 mRNA

NCBI chr16:19,592,067...19,599,998
Ensembl chr16:19,595,655...19,599,998

G

lysophosphatidic acid receptor 4

decreases expression

Diquat results in decreased expression of LPAR4 mRNA

NCBI chr X:72,033,486...72,046,978
Ensembl chr X:72,033,486...72,046,977

G

lipoprotein lipase

decreases expression

Diquat results in decreased expression of LPL mRNA; Diquat results in decreased expression of LPL protein

NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249

G

lactoperoxidase

increases expression

Diquat results in increased expression of LPO mRNA

NCBI chr10:72,606,950...72,626,220
Ensembl chr10:72,606,944...72,626,535

G

leucine-rich alpha-2-glycoprotein 1

increases expression

Diquat results in increased expression of LRG1 mRNA

NCBI chr 9:947,516...949,773
Ensembl chr 9:947,516...949,813

G

leucine-rich repeat, Ig-like and transmembrane domains 1

increases expression

Diquat results in increased expression of LRIT1 mRNA

NCBI chr16:12,822,076...12,830,003
Ensembl chr16:12,822,076...12,831,772

G

leucine rich melanocyte differentiation associated

increases expression

Diquat results in increased expression of LRMDA mRNA

NCBI chr15:1,223,098...2,284,764
Ensembl chr15:1,225,710...2,284,749

G

leucine rich repeat containing 18

decreases expression

Diquat results in decreased expression of LRRC18 mRNA

NCBI chr16:8,253,524...8,277,141
Ensembl chr16:8,254,352...8,277,437

G

leucine rich repeat containing 55

decreases expression

Diquat results in decreased expression of LRRC55 mRNA

NCBI chr 3:70,269,908...70,280,651
Ensembl chr 3:70,265,936...70,278,639

G

leucine-rich repeats and IQ motif containing 1

decreases expression

Diquat results in decreased expression of LRRIQ1 mRNA

NCBI chr 7:38,317,259...38,409,885
Ensembl chr 7:38,192,759...38,409,901

G

LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated

decreases expression

Diquat results in decreased expression of LSM5 mRNA

NCBI chr 4:85,951,073...85,954,289
Ensembl chr 6:104,652,477...104,654,165
Ensembl chr 4:104,652,477...104,654,165

G

lymphotoxin beta

decreases expression

Diquat results in decreased expression of LTB mRNA

NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381

G

latent transforming growth factor beta binding protein 1

decreases expression

Diquat results in decreased expression of LTBP1 mRNA

NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349

G

latent transforming growth factor beta binding protein 4

decreases expression

Diquat results in decreased expression of LTBP4 mRNA; Diquat results in decreased expression of LTBP4 protein

NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178

G

lumican

decreases expression

Diquat results in decreased expression of LUM mRNA

NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793

G

lymphocyte antigen 86

decreases expression

Diquat results in decreased expression of LY86 mRNA

NCBI chr17:27,415,807...27,499,695
Ensembl chr17:27,415,830...27,487,260

G

lymphocyte antigen 9

decreases expression

Diquat results in decreased expression of LY9 mRNA

NCBI chr13:84,079,345...84,100,783
Ensembl chr13:84,079,458...84,100,823

G

lysophospholipase 1

decreases expression

Diquat results in decreased expression of LYPLA1 mRNA

NCBI chr 5:14,679,605...14,708,774
Ensembl chr 5:14,679,606...14,708,746

G

LYR motif containing 7

increases expression

Diquat results in increased expression of LYRM7 protein

NCBI chr10:38,964,299...38,983,628
Ensembl chr10:38,964,311...38,983,601

G

mab-21 like 3

increases expression

Diquat results in increased expression of MAB21L3 mRNA

NCBI chr 2:189,248,895...189,271,652
Ensembl chr 2:189,248,895...189,271,652

G

mab-21 like 4

increases expression

Diquat results in increased expression of MAB21L4 mRNA

NCBI chr 9:93,690,455...93,701,267
Ensembl chr 9:93,690,999...93,700,506

G

mitotic arrest deficient 2 like 2

increases expression

Diquat results in increased expression of MAD2L2 mRNA

NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693

G

MAF bZIP transcription factor F

increases expression

Diquat results in increased expression of MAFF mRNA

NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851

G

mannosidase, alpha, class 2B, member 2

decreases expression

Diquat results in decreased expression of MAN2B2 protein

NCBI chr14:73,969,079...73,994,089
Ensembl chr14:73,969,003...74,004,281

G

monoamine oxidase B

increases expression

Diquat results in increased expression of MAOB mRNA

NCBI chr X:5,907,327...6,010,996
Ensembl chr X:5,907,266...6,011,003

G

microtubule-associated protein 1 light chain 3 beta

multiple interactions
increases expression

[Diquat co-treated with procyanidin B2] results in increased expression of MAP1LC3B mRNA
Diquat results in increased expression of MAP1LC3B protein
Diquat results in increased lipidation of and results in increased localization of MAP1LC3B protein; MAP1LC3B protein promotes the reaction [Diquat results in decreased expression of and results in increased degradation of FTH1 protein]; MAP1LC3B protein promotes the reaction [Diquat results in decreased expression of FTH1 protein]

PMID:27057282 PMID:38128689

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690

G

microtubule-associated protein 2

increases expression

Diquat results in increased expression of MAP2 mRNA

NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809

G

mitogen activated protein kinase kinase 1

increases expression

Diquat results in increased expression of MAP2K1 protein

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase kinase 3

increases expression

Diquat results in increased expression of MAP2K3 mRNA

NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492

G

mitogen activated protein kinase kinase kinase 3

decreases expression

Diquat results in decreased expression of MAP3K3 protein

NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848

G

mitogen-activated protein kinase kinase kinase 6

increases expression

Diquat results in increased expression of MAP3K6 mRNA

NCBI chr 5:145,440,126...145,452,213
Ensembl chr 5:145,440,346...145,452,212

G

MAP7 domain containing 2

increases expression

Diquat results in increased expression of MAP7D2 mRNA

NCBI chr X:35,372,453...35,488,073
Ensembl chr X:35,372,700...35,488,091

G

mitogen activated protein kinase 1

increases phosphorylation

Diquat results in increased phosphorylation of MAPK1 protein

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

increases phosphorylation

Diquat results in increased phosphorylation of MAPK3 protein

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 9

multiple interactions

PROP1 protein affects the reaction [Diquat affects the phosphorylation of MAPK9 protein]

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

G

microtubule-associated protein, RP/EB family, member 3

increases expression

Diquat results in increased expression of MAPRE3 mRNA

NCBI chr 6:25,513,800...25,558,876
Ensembl chr 6:25,513,800...25,558,881

G

membrane associated ring-CH-type finger 4

increases expression

Diquat results in increased expression of MARCHF4 protein

NCBI chr 9:74,078,437...74,196,070
Ensembl chr 9:74,078,434...74,198,199

G

myristoylated alanine rich protein kinase C substrate

decreases expression

Diquat results in decreased expression of MARCKS mRNA

NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012

G

microtubule associated serine/threonine kinase-like

decreases expression

Diquat results in decreased expression of MASTL mRNA

NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353

G

matrilin 2

decreases expression

Diquat results in decreased expression of MATN2 mRNA

NCBI chr 7:65,494,996...65,644,613
Ensembl chr 7:65,494,834...65,645,113

G

MYC associated zinc finger protein

increases expression

Diquat results in increased expression of MAZ protein

NCBI chr 1:181,629,742...181,635,193
Ensembl chr 1:181,629,729...181,650,408

G

muscleblind-like splicing regulator 1

increases expression

Diquat results in increased expression of MBNL1 protein

NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:144,670,285...144,814,368

G

minichromosome maintenance complex component 6

decreases expression

Diquat results in decreased expression of MCM6 mRNA

NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960

G

malic enzyme 1

increases expression

Diquat results in increased expression of ME1 mRNA

NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304

G

mediator complex subunit 14

decreases expression

Diquat results in decreased expression of MED14 mRNA

NCBI chr X:10,036,749...10,127,910
Ensembl chr X:10,036,805...10,126,240

G

myocyte enhancer factor 2C

decreases expression

Diquat results in decreased expression of MEF2C mRNA

NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880

G

Meis homeobox 2

decreases expression

Diquat results in decreased expression of MEIS2 mRNA

NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696

G

meprin A subunit beta

decreases expression

Diquat results in decreased expression of MEP1B mRNA

NCBI chr18:12,366,126...12,392,840
Ensembl chr18:12,365,289...12,392,840

G

methyltransferase 1, tRNA methylguanosine

increases expression

Diquat results in increased expression of METTL1 protein

NCBI chr 7:62,864,860...62,869,202
Ensembl chr 7:62,864,853...62,869,202

G

methyltransferase 5, N6-adenosine

decreases expression

Diquat results in decreased expression of METTL5 protein

NCBI chr 3:54,625,790...54,638,066
Ensembl chr 3:54,625,793...54,638,039

G

mitofusin 2

decreases expression

Diquat results in decreased expression of MFN2 protein

NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342

G

major facilitator superfamily domain containing 12

increases expression

Diquat results in increased expression of MFSD12 mRNA

NCBI chr 7:8,345,171...8,354,050
Ensembl chr 7:8,347,314...8,353,988

G

major facilitator superfamily domain containing 8

decreases expression

Diquat results in decreased expression of MFSD8 protein

NCBI chr 2:123,822,042...123,847,808
Ensembl chr 2:123,816,614...123,857,971

G

monoglyceride lipase

increases expression

Diquat results in increased expression of MGLL mRNA

NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179

G

matrix Gla protein

decreases expression

Diquat results in decreased expression of MGP mRNA

NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667

G

microsomal glutathione S-transferase 1

increases expression

Diquat results in increased expression of MGST1 mRNA

NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892

G

microsomal glutathione S-transferase 3

increases expression

Diquat results in increased expression of MGST3 mRNA

NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411

G

MIB E3 ubiquitin protein ligase 2

decreases expression

Diquat results in decreased expression of MIB2 protein

NCBI chr 5:166,243,776...166,259,944
Ensembl chr 5:166,243,776...166,259,650

G

macrophage migration inhibitory factor

increases expression

Diquat results in increased expression of MIF mRNA

NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504

G

MIF4G domain containing

increases expression

Diquat results in increased expression of MIF4GD protein

NCBI chr10:100,847,168...100,852,166

G

marker of proliferation Ki-67

decreases expression

Diquat results in decreased expression of MKI67 mRNA

NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762

G

muskelin 1

increases expression

Diquat results in increased expression of MKLN1 protein

NCBI chr 4:59,815,912...60,124,047
Ensembl chr 4:60,002,464...60,123,993

G

MAPK interacting serine/threonine kinase 2

increases expression

Diquat results in increased expression of MKNK2 mRNA

NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827

G

matrix metallopeptidase 12

decreases expression

Diquat results in decreased expression of MMP12 mRNA

NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611

G

matrix metallopeptidase 13

decreases expression

Diquat results in decreased expression of MMP13 mRNA

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

G

matrix metallopeptidase 2

decreases expression

Diquat results in decreased expression of MMP2 mRNA

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

molybdenum cofactor synthesis 2

increases expression

Diquat results in increased expression of MOCS2 protein

NCBI chr 2:46,504,588...46,516,327
Ensembl chr 2:46,504,588...46,516,324

G

macrophage expressed 1

decreases expression

Diquat results in decreased expression of MPEG1 mRNA

NCBI chr 1:209,452,176...209,456,692
Ensembl chr 1:209,452,133...209,458,855

G

myeloperoxidase

multiple interactions
increases activity

Capsaicin inhibits the reaction [Diquat results in increased activity of MPO protein]

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

G

MAGUK p55 scaffold protein 4

decreases expression

Diquat results in decreased expression of MPP4 mRNA

NCBI chr 9:60,569,734...60,613,035
Ensembl chr 9:60,569,734...60,611,797

G

MPV17 mitochondrial inner membrane protein like

decreases expression

Diquat results in decreased expression of MPV17L mRNA

NCBI chr10:1,988,451...2,025,300
Ensembl chr10:1,988,136...2,007,649

G

mannose receptor, C type 2

decreases expression

Diquat results in decreased expression of MRC2 mRNA

NCBI chr10:90,261,986...90,323,187
Ensembl chr10:90,261,394...90,322,856

G

MRE11 homolog, double strand break repair nuclease

increases expression

Diquat results in increased expression of MRE11 protein

NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279

G

mitochondrial ribosomal protein L1

increases expression

Diquat results in increased expression of MRPL1 protein

NCBI chr14:13,300,522...13,359,654
Ensembl chr14:13,300,522...13,359,721

G

mitochondrial ribosomal protein L30

increases expression

Diquat results in increased expression of MRPL30 protein

NCBI chr 9:40,125,352...40,136,189
Ensembl chr 9:40,125,430...40,137,257

G

mitochondrial ribosomal protein S25

increases expression

Diquat results in increased expression of MRPS25 protein

NCBI chr 4:124,668,320...124,680,086
Ensembl chr 4:124,668,094...124,680,057

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1

decreases expression

Diquat results in decreased expression of ND1 protein

NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2

decreases expression

Diquat results in decreased expression of ND2 protein

NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942

G

metallothionein 1

decreases expression
multiple interactions
increases expression

Diquat results in decreased expression of MT1 mRNA
PROP1 protein affects the reaction [Diquat results in decreased expression of MT1 mRNA]
Diquat results in increased expression of MT1 mRNA

PMID:20826540 PMID:36851058

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049

G

metallothionein 2A

decreases expression
multiple interactions
increases expression

Diquat results in decreased expression of MT2 mRNA
PROP1 protein affects the reaction [Diquat results in decreased expression of MT2 mRNA]
Diquat results in increased expression of MT2 mRNA

PMID:20826540 PMID:36851058

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

metastasis associated 1 family, member 3

increases expression

Diquat results in increased expression of MTA3 protein

NCBI chr 6:10,867,028...10,987,221
Ensembl chr 6:10,867,011...10,986,883

G

mitochondrial amidoxime reducing component 1

increases expression

Diquat results in increased expression of MTARC1 mRNA

NCBI chr13:96,324,377...96,362,677
Ensembl chr13:96,339,757...96,397,796

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

increases expression

Diquat results in increased expression of MTHFD2 mRNA

NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608

G

mitochondrial translational initiation factor 3

decreases expression

Diquat results in decreased expression of MTIF3 protein

NCBI chr12:8,126,193...8,140,706
Ensembl chr12:8,126,276...8,140,470

G

myotubularin related protein 7

decreases expression

Diquat results in decreased expression of MTMR7 mRNA

NCBI chr16:51,641,267...51,732,212
Ensembl chr16:51,641,190...51,732,182

G

mitochondrial tRNA translation optimization 1

decreases expression

Diquat results in decreased expression of MTO1 protein

NCBI chr 8:79,309,681...79,335,231
Ensembl chr 8:79,309,982...79,335,231

G

Mtr4 exosome RNA helicase

decreases expression

Diquat results in decreased expression of MTREX mRNA

NCBI chr 2:44,500,326...44,560,624
Ensembl chr 2:44,461,444...44,560,627

G

matrix remodeling associated 8

decreases expression

Diquat results in decreased expression of MXRA8 protein

NCBI chr 5:166,448,919...166,453,645
Ensembl chr 5:166,449,154...166,453,636

G

MYC proto-oncogene, bHLH transcription factor

increases expression

Diquat results in increased expression of MYC mRNA

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

myc target 1

decreases expression

Diquat results in decreased expression of MYCT1 mRNA; Diquat results in decreased expression of MYCT1 protein

NCBI chr 1:42,018,137...42,029,410
Ensembl chr 1:42,018,137...42,029,410

G

myosin light chain 9

decreases expression

Diquat results in decreased expression of MYL9 protein

NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333

G

myosin light chain kinase 3

decreases expression

Diquat results in decreased expression of MYLK3 mRNA

NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954

G

myosin IG

decreases expression

Diquat results in decreased expression of MYO1G mRNA

NCBI chr14:81,386,701...81,401,843
Ensembl chr14:81,386,701...81,401,843

G

myosin VA

decreases expression

Diquat results in decreased expression of MYO5A mRNA

NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918

G

myomesin 3

decreases expression

Diquat results in decreased expression of MYOM3 mRNA

NCBI chr 5:147,992,737...148,043,282
Ensembl chr 5:147,992,737...148,043,274

G

N(alpha)-acetyltransferase 80, NatH catalytic subunit

increases expression

Diquat results in increased expression of NAA80 mRNA

NCBI chr 8:108,254,314...108,257,564
Ensembl chr 8:108,253,302...108,257,563

G

N-acetylglutamate synthase

increases expression

Diquat results in increased expression of NAGS mRNA

NCBI chr10:87,098,330...87,102,465
Ensembl chr10:87,098,330...87,102,465

G

NLR family, apoptosis inhibitory protein 6

decreases expression

Diquat results in decreased expression of NAIP2 mRNA

NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542

G

sodium leak channel, non-selective

decreases expression

Diquat results in decreased expression of NALCN mRNA

NCBI chr15:100,398,583...100,741,243
Ensembl chr15:100,398,615...100,741,001

G

N-acetyltransferase 8 (GCN5-related) family member 3

decreases expression

Diquat results in decreased expression of NAT8F3 protein

NCBI chr 4:118,241,792...118,246,010
Ensembl chr 4:118,239,304...118,285,500

G

N-acetyltransferase 8 (GCN5-related) family member 5

increases expression

Diquat results in increased expression of NAT8F5 mRNA

NCBI chr 4:118,260,323...118,285,038
Ensembl chr 4:118,260,252...118,285,704

G

NCK adaptor protein 2

decreases expression

Diquat results in decreased expression of NCK2 protein

NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307

G

NCK associated protein 1 like

decreases expression

Diquat results in decreased expression of NCKAP1L mRNA

NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934

G

nuclear receptor coactivator 4

increases expression

Diquat results in increased expression of NCOA4 mRNA

NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641

G

neuronal calcium sensor 1

increases expression

Diquat results in increased expression of NCS1 mRNA

NCBI chr 3:14,523,220...14,568,829
Ensembl chr 3:14,523,220...14,568,829

G

N-myc downstream regulated 1

increases expression

Diquat results in increased expression of NDRG1 mRNA

NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880

G

NDRG family member 4

decreases expression

Diquat results in decreased expression of NDRG4 mRNA

NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914

G

N-deacetylase and N-sulfotransferase 3

decreases expression

Diquat results in decreased expression of NDST3 mRNA

NCBI chr 2:211,702,728...211,868,159
Ensembl chr 2:211,704,898...211,854,584

G

NADH:ubiquinone oxidoreductase subunit A11

decreases expression

Diquat results in decreased expression of NDUFA11 protein

NCBI chr 9:1,550,487...1,554,546
Ensembl chr 9:1,550,468...1,555,601

G

nectin cell adhesion molecule 1

increases expression

Diquat results in increased expression of NECTIN1 mRNA

NCBI chr 8:44,101,776...44,164,863
Ensembl chr 8:44,101,776...44,189,787

G

neurofilament heavy chain

affects expression

Diquat affects the expression of NEFH mRNA

NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351

G

nuclear envelope integral membrane protein 1

increases expression

Diquat results in increased expression of NEMP1 protein

NCBI chr 7:63,514,025...63,538,791
Ensembl chr 7:63,479,951...63,534,602

G

NFE2 like bZIP transcription factor 2

increases expression
increases activity
multiple interactions
decreases response to substance
increases response to substance
decreases expression

Diquat results in increased expression of NFE2L2 protein
Diquat results in increased activity of NFE2L2 protein
[Ellagic Acid co-treated with Diquat] results in increased expression of NFE2L2 mRNA; Ascorbic Acid inhibits the reaction [Diquat results in decreased expression of NFE2L2 protein]; Ellagic Acid inhibits the reaction [Diquat results in decreased expression of NFE2L2 mRNA]; KEAP1 gene mutant form inhibits the reaction [NFE2L2 gene mutant form results in increased susceptibility to Diquat]; NFE2L2 gene mutant form promotes the reaction [Diquat results in decreased abundance of Glutathione]; PROP1 protein affects the reaction [Diquat results in increased expression of NFE2L2 protein]
NFE2L2 results in decreased susceptibility to Diquat
Diquat results in decreased expression of NFE2L2 mRNA; Diquat results in decreased expression of NFE2L2 protein

PMID:16962985 PMID:20143881 PMID:20826540 PMID:21172416 PMID:22762311 More...

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor kappa B subunit 1

increases expression
multiple interactions

Diquat results in increased expression of NFKB1 mRNA
THBD protein modified form inhibits the reaction [Diquat results in increased expression of NFKB1 mRNA]

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

G

NFKB inhibitor alpha

increases expression

Diquat results in increased expression of NFKBIA mRNA; Diquat results in increased expression of NFKBIA protein

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

nuclear factor related to kappa B binding protein

decreases expression

Diquat results in decreased expression of NFRKB protein

NCBI chr 8:29,831,802...29,863,360
Ensembl chr 8:29,831,812...29,863,359

G

nuclear transcription factor Y subunit beta

increases expression

Diquat results in increased expression of NFYB protein

NCBI chr 7:20,964,988...20,980,569
Ensembl chr 7:20,964,993...20,980,565

G

nidogen 1

decreases expression

Diquat results in decreased expression of NID1 mRNA

NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267

G

Sodium/potassium transporting ATPase interacting 1

increases expression

Diquat results in increased expression of NKAIN1 mRNA

NCBI chr 5:142,747,702...142,792,665
Ensembl chr 5:142,747,505...142,791,863

G

neuroligin 1

decreases expression

Diquat results in decreased expression of NLGN1 mRNA

NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464

G

NLR family, CARD domain containing 4

decreases expression

Diquat results in decreased expression of NLRC4 mRNA

NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248

G

NLR family, CARD domain containing 5

decreases expression

Diquat results in decreased expression of NLRC5 mRNA

NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121

G

N-myristoyltransferase 2

increases expression

Diquat results in increased expression of NMT2 protein

NCBI chr17:74,917,833...74,964,788
Ensembl chr17:74,917,833...74,961,080

G

nocturnin

increases expression

Diquat results in increased expression of NOCT mRNA

NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400

G

nucleolar protein 3

decreases expression

Diquat results in decreased expression of NOL3 protein

NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250

G

nucleolar and coiled-body phosphoprotein 1

decreases expression

Diquat results in decreased expression of NOLC1 protein

NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088

G

nitric oxide synthase 2

decreases expression

Diquat results in decreased expression of NOS2 mRNA

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

NOTUM, palmitoleoyl-protein carboxylesterase

increases expression

Diquat results in increased expression of NOTUM mRNA

NCBI chr10:105,933,245...105,940,327
Ensembl chr10:105,933,249...105,940,315

G

nucleophosmin/nucleoplasmin, 3

decreases expression

Diquat results in decreased expression of NPM3 mRNA

NCBI chr 1:244,595,638...244,597,623
Ensembl chr 1:244,595,644...244,597,591

G

natriuretic peptide B

increases expression

Diquat results in increased expression of NPPB mRNA

NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168

G

natriuretic peptide receptor 3

decreases expression

Diquat results in decreased expression of NPR3 mRNA

NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955

G

NAD(P)H quinone dehydrogenase 1

increases expression
increases activity
multiple interactions
decreases expression

Diquat results in increased expression of NQO1 mRNA; Diquat results in increased expression of NQO1 protein
Diquat results in increased activity of NQO1 protein
Ascorbic Acid inhibits the reaction [Diquat results in decreased expression of NQO1 protein]; Ellagic Acid inhibits the reaction [Diquat results in decreased expression of NQO1 mRNA]; PROP1 protein affects the reaction [Diquat results in increased expression of NQO1 mRNA]
Diquat results in decreased expression of NQO1 mRNA; Diquat results in decreased expression of NQO1 protein

PMID:20826540 PMID:21172416 PMID:33475796 PMID:35268077 PMID:36572071 More...

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 1, group I, member 2

increases expression

Diquat results in increased expression of NR1I2 mRNA

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

increases expression

Diquat results in increased expression of NR1I3 mRNA

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

nuclear receptor subfamily 2, group E, member 3

decreases expression

Diquat results in decreased expression of NR2E3 mRNA

NCBI chr 8:60,365,581...60,373,383
Ensembl chr 8:60,366,124...60,373,163

G

nuclear receptor subfamily 2, group F, member 6

decreases expression

Diquat results in decreased expression of NR2F6 protein

NCBI chr16:18,046,012...18,053,914
Ensembl chr16:18,046,013...18,053,459

G

neuronal regeneration related protein

decreases expression

Diquat results in decreased expression of NREP mRNA

NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591

G

neuregulin 1

increases expression

Diquat results in increased expression of NRG1 mRNA

NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884

G

nuclear receptor interacting protein 2

decreases expression

Diquat results in decreased expression of NRIP2 protein

NCBI chr 4:161,673,964...161,684,055
Ensembl chr 4:161,639,356...161,684,070

G

neuropilin 2

decreases expression

Diquat results in decreased expression of NRP2 mRNA

NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958

G

NSE3 homolog, SMC5-SMC6 complex component

increases expression

Diquat results in increased expression of NSMCE3 protein

NCBI chr 1:118,401,302...118,402,629

G

NOP2/Sun RNA methyltransferase family member 7

increases expression

Diquat results in increased expression of NSUN7 mRNA

NCBI chr14:41,878,562...41,935,238
Ensembl chr14:41,879,293...41,934,949

G

NUAK family kinase 2

increases expression

Diquat results in increased expression of NUAK2 mRNA

NCBI chr13:43,753,454...43,770,604
Ensembl chr13:43,753,832...43,770,604

G

NUBP iron-sulfur cluster assembly factor 2

decreases expression

Diquat results in decreased expression of NUBP2 protein

NCBI chr10:13,903,224...13,906,928
Ensembl chr10:13,903,224...13,906,969

G

nucleobindin 2

decreases expression

Diquat results in decreased expression of NUCB2 protein

NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353

G

nudix hydrolase 2

decreases expression

Diquat results in decreased expression of NUDT2 protein

NCBI chr 5:56,628,265...56,643,104
Ensembl chr 5:56,628,265...56,643,104

G

nudix hydrolase 7

increases expression

Diquat results in increased expression of NUDT7 protein

NCBI chr19:42,125,679...42,151,198
Ensembl chr19:42,125,711...42,151,081

G

NACHT and WD repeat domain containing 2

decreases expression

Diquat results in decreased expression of NWD2 mRNA

NCBI chr14:44,480,049...44,671,417
Ensembl chr14:44,482,287...44,670,299

G

ornithine decarboxylase 1

decreases expression

Diquat results in decreased expression of ODC1 mRNA

NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440

G

OPA1, mitochondrial dynamin like GTPase

decreases expression

Diquat results in decreased expression of OPA1 protein

NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109

G

5-oxoprolinase (ATP-hydrolysing)

increases expression

Diquat results in increased expression of OPLAH mRNA

NCBI chr 7:108,011,472...108,051,751
Ensembl chr 7:108,011,475...108,035,297

G

ORMDL sphingolipid biosynthesis regulator 1

decreases expression

Diquat results in decreased expression of ORMDL1 protein

NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211

G

OTU deubiquitinase, ubiquitin aldehyde binding 1

decreases expression

Diquat results in decreased expression of OTUB1 protein

NCBI chr 1:204,387,215...204,395,495
Ensembl chr 1:204,387,215...204,395,483

G

OXA1L, mitochondrial inner membrane protein

increases expression

Diquat results in increased expression of OXA1L protein

NCBI chr15:27,813,688...27,821,319
Ensembl chr15:27,813,625...27,821,319

G

P2Y receptor family member 10

decreases expression

Diquat results in decreased expression of P2RY10 mRNA

NCBI chr X:72,121,558...72,207,174
Ensembl chr X:72,111,264...72,212,265

G

prolyl 3-hydroxylase 3

decreases expression

Diquat results in decreased expression of P3H3 protein

NCBI chr 4:157,646,242...157,662,035
Ensembl chr 4:157,646,243...157,662,035

G

prolyl 4-hydroxylase subunit alpha 2

increases expression

Diquat results in increased expression of P4HA2 mRNA

NCBI chr10:38,243,136...38,271,983
Ensembl chr10:38,243,139...38,287,314

G

phenylalanine hydroxylase

decreases expression

Diquat results in decreased expression of PAH mRNA

NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130

G

progestin and adipoQ receptor family member 8

decreases expression

Diquat results in decreased expression of PAQR8 mRNA

NCBI chr 9:23,312,521...23,362,175
Ensembl chr 9:23,312,585...23,362,340

G

poly (ADP-ribose) polymerase 1

increases cleavage

Diquat results in increased cleavage of PARP1 protein

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

poly (ADP-ribose) polymerase family, member 10

increases expression

Diquat results in increased expression of PARP10 mRNA

NCBI chr 7:107,949,031...107,958,377
Ensembl chr 7:107,949,043...107,958,304

G

poly (ADP-ribose) polymerase family, member 14

decreases expression

Diquat results in decreased expression of PARP14 mRNA

NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916

G

PARP1 binding protein

decreases expression

Diquat results in decreased expression of PARPBP mRNA

NCBI chr 7:22,511,427...22,580,834
Ensembl chr 7:22,511,427...22,573,695

G

pro-apoptotic WT1 regulator

decreases expression

Diquat results in decreased expression of PAWR protein

NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028

G

PDZ binding kinase

decreases expression

Diquat results in decreased expression of PBK mRNA

NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014

G

PBX homeobox 4

increases expression

Diquat results in increased expression of PBX4 mRNA

NCBI chr16:19,555,089...19,590,054
Ensembl chr16:19,555,090...19,590,014

G

poly(rC) binding protein 1

decreases expression

Diquat results in decreased expression of PCBP1 protein

NCBI chr 4:118,972,698...118,974,705
Ensembl chr 4:118,972,661...118,976,500

G

poly(rC) binding protein 2

decreases expression

Diquat results in decreased expression of PCBP2 protein

NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863

G

protocadherin 12

decreases expression

Diquat results in decreased expression of PCDH12 mRNA

NCBI chr18:30,103,728...30,119,307
Ensembl chr18:30,103,728...30,119,307

G

protocadherin 18

decreases expression

Diquat results in decreased expression of PCDH18 mRNA

NCBI chr 2:133,831,996...133,845,992
Ensembl chr 2:133,832,001...133,845,883

G

protocadherin beta 19

decreases expression

Diquat results in decreased expression of PCDHB12 mRNA

NCBI chr18:29,204,838...29,207,646

G

phosphoenolpyruvate carboxykinase 1

increases expression

Diquat results in increased expression of PCK1 mRNA; Diquat results in increased expression of PCK1 protein

NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191

G

PEST proteolytic signal containing nuclear protein

decreases expression

Diquat results in decreased expression of PCNP protein

NCBI chr11:44,592,766...44,607,372
Ensembl chr11:44,592,742...44,607,348

G

procollagen C-endopeptidase enhancer 2

decreases expression

Diquat results in decreased expression of PCOLCE2 mRNA

NCBI chr 8:96,193,461...96,251,116
Ensembl chr 8:96,193,461...96,251,114

G

proprotein convertase subtilisin/kexin type 4

increases expression

Diquat results in increased expression of PCSK4 mRNA

NCBI chr 7:9,381,366...9,389,589
Ensembl chr 7:9,381,361...9,389,585

G

phosphodiesterase 2A

decreases expression

Diquat results in decreased expression of PDE2A protein

NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434

G

phosphodiesterase 6A

decreases expression

Diquat results in decreased expression of PDE6A mRNA

NCBI chr18:54,676,863...54,748,640
Ensembl chr18:54,676,863...54,748,816

G

platelet derived growth factor receptor alpha

decreases expression

Diquat results in decreased expression of PDGFRA mRNA

NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335

G

pyruvate dehydrogenase kinase 4

increases expression

Diquat results in increased expression of PDK4 mRNA; Diquat results in increased expression of PDK4 protein

NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850

G

PDZ and LIM domain 3

increases expression

Diquat results in increased expression of PDLIM3 protein

NCBI chr16:46,352,460...46,383,680
Ensembl chr16:46,352,467...46,383,657

G

podoplanin

increases expression

Diquat results in increased expression of PDPN protein

NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656

G

pyridoxal kinase

increases expression

Diquat results in increased expression of PDXK mRNA

NCBI chr20:10,210,276...10,232,314
Ensembl chr20:10,210,289...10,232,110

G

phosphogluconate dehydrogenase

increases expression

Diquat results in increased expression of PGD mRNA

PMID:16962985 PMID:36851058

NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778

G

6-phosphogluconolactonase

increases expression

Diquat results in increased expression of PGLS mRNA

NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803

G

PHD finger protein 11

decreases expression

Diquat results in decreased expression of PHF11D mRNA

NCBI chr15:33,390,290...33,414,647
Ensembl chr15:33,390,292...33,413,009

G

PHD finger protein 8

decreases expression

Diquat results in decreased expression of PHF8 protein

NCBI chr X:20,524,103...20,623,459
Ensembl chr X:20,524,558...20,623,410

G

PILR alpha associated neural protein

decreases expression

Diquat results in decreased expression of PIANP mRNA

NCBI chr 4:157,796,425...157,804,842
Ensembl chr 4:157,798,808...157,804,842

G

phosphoinositide-3-kinase adaptor protein 1

decreases expression

Diquat results in decreased expression of PIK3AP1 mRNA

NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828

G

phosphatidylinositol 3-kinase, catalytic subunit type 3

multiple interactions

[Diquat co-treated with procyanidin B2] results in increased expression of PIK3C3 mRNA

NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

decreases expression

Diquat results in decreased expression of PIK3CD mRNA

NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

decreases expression

Diquat results in decreased expression of PIK3CG mRNA

NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043

G

phosphoinositide-3-kinase regulatory subunit 2

decreases expression

Diquat results in decreased expression of PIK3R2 protein

NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065

G

paired immunoglobin-like type 2 receptor beta 1

decreases expression

Diquat results in decreased expression of PILRB1 mRNA

NCBI chr12:18,516,161...18,525,375
Ensembl chr12:18,516,156...18,525,346

G

Pim-3 proto-oncogene, serine/threonine kinase

increases expression

Diquat results in increased expression of PIM3 mRNA

NCBI chr 7:119,953,377...119,956,587
Ensembl chr 7:119,953,175...119,956,587

G

pirin

increases expression

Diquat results in increased expression of PIR mRNA

NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218

G

cAMP-dependent protein kinase inhibitor alpha

decreases expression

Diquat results in decreased expression of PKIA mRNA

NCBI chr 2:94,398,869...94,473,638
Ensembl chr 2:94,398,869...94,414,282

G

pyruvate kinase L/R

increases expression

Diquat results in increased expression of PKLR mRNA

NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870

G

phospholipase A2, group XIIA

increases expression

Diquat results in increased expression of PLA2G12A mRNA

NCBI chr 2:218,436,497...218,452,742
Ensembl chr 2:218,436,513...218,452,740

G

phospholipase A2 receptor 1

decreases expression

Diquat results in decreased expression of PLA2R1 mRNA

NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660

G

phospholipase B domain containing 2

decreases expression

Diquat results in decreased expression of PLBD2 protein

NCBI chr12:36,062,802...36,081,984
Ensembl chr12:36,062,802...36,081,983

G

phospholipase C, beta 2

decreases expression

Diquat results in decreased expression of PLCB2 mRNA

NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302

G

phosphatidylinositol-specific phospholipase C, X domain containing 1

increases expression

Diquat results in increased expression of PLCXD1 mRNA

NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392

G

pleckstrin homology and coiled-coil domain containing D1

decreases expression

Diquat results in decreased expression of PLEKHD1 protein

NCBI chr 6:100,340,655...100,371,942
Ensembl chr 6:100,340,655...100,371,941

G

perilipin 2

increases expression

Diquat results in increased expression of PLIN2 mRNA

NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319

G

perilipin 4

increases expression

Diquat results in increased expression of PLIN4 mRNA

NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056

G

perilipin 5

increases expression

Diquat results in increased expression of PLIN5 mRNA

NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120

G

polo-like kinase 3

increases expression

Diquat results in increased expression of PLK3 mRNA

NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317

G

phospholipid phosphatase 4

decreases expression

Diquat results in decreased expression of PLPP4 mRNA

NCBI chr 1:183,829,794...183,959,319
Ensembl chr 1:183,830,409...183,959,319

G

plexin A4

decreases expression

Diquat results in decreased expression of PLXNA4 mRNA

NCBI chr 4:60,720,246...61,162,206
Ensembl chr 4:60,720,255...61,162,206

G

plexin C1

decreases expression

Diquat results in decreased expression of PLXNC1 mRNA

NCBI chr 7:29,390,038...29,543,985
Ensembl chr 7:29,390,048...29,543,779

G

plexin D1

decreases expression

Diquat results in decreased expression of PLXND1 mRNA

NCBI chr 4:149,002,786...149,043,097
Ensembl chr 4:149,002,784...149,043,244

G

POP4 homolog, ribonuclease P/MRP subunit

decreases expression

Diquat results in decreased expression of POP4 protein

NCBI chr 1:90,960,026...90,968,360
Ensembl chr 1:90,960,022...90,968,443

G

cytochrome p450 oxidoreductase

multiple interactions
increases metabolic processing

[[Iron co-treated with POR protein] results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical; [Iron co-treated with POR protein] results in increased metabolism of Diquat; [POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydrogen Peroxide; [POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical; [POR protein results in increased metabolism of Diquat] which results in increased abundance of Superoxides; CAT protein inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydrogen Peroxide]; diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydrogen Peroxide]; diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Superoxides]; diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased metabolism of NADP]; diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased metabolism of Oxygen]; NADP promotes the reaction [[POR protein results in increased metabolism of Diquat] which results in increased metabolism of Oxygen]
[POR protein results in increased metabolism of Diquat] which results in increased metabolism of NADP; [POR protein results in increased metabolism of Diquat] which results in increased metabolism of Oxygen; POR protein results in increased metabolism of Diquat
[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydrogen Peroxide; [POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical; [POR protein results in increased metabolism of Diquat] which results in increased abundance of Superoxides; CAT protein inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydrogen Peroxide]; Dimethyl Sulfoxide inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical]; diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydrogen Peroxide]; diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical]; diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Superoxides]; diphenyleneiodonium inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased metabolism of NADP]
[POR protein results in increased metabolism of Diquat] which results in increased metabolism of NADP; POR protein results in increased metabolism of Diquat

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

G

periostin

decreases expression

Diquat results in decreased expression of POSTN mRNA

NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099

G

PTPRF interacting protein alpha 3

decreases expression

Diquat results in decreased expression of PPFIA3 protein

NCBI chr 1:95,817,110...95,845,950
Ensembl chr 1:95,817,110...95,845,798

G

peptidylprolyl isomerase F

increases expression

Diquat results in increased expression of PPIF mRNA

NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913

G

protein phosphatase 1, regulatory subunit 15A

increases expression

Diquat results in increased expression of PPP1R15A mRNA

PMID:21172416 PMID:36851058

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

G

polyglutamine binding protein 1

decreases expression

Diquat results in decreased expression of PQBP1 protein

NCBI chr X:14,603,516...14,608,091
Ensembl chr X:14,603,539...14,608,087

G

peroxiredoxin 1

increases expression

Diquat results in increased expression of PRDX1 mRNA

NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856

G

peroxiredoxin 3

increases expression

Diquat results in increased expression of PRDX3 mRNA

NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111

G

proline and arginine rich end leucine rich repeat protein

decreases expression

Diquat results in decreased expression of PRELP mRNA

NCBI chr13:45,368,407...45,391,480
Ensembl chr13:45,370,533...45,380,270

G

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2

decreases expression

Diquat results in decreased expression of PREX2 mRNA

NCBI chr 5:7,937,692...8,253,112
Ensembl chr 5:7,942,573...8,253,068

G

proteoglycan 4

increases expression

Diquat results in increased expression of PRG4 mRNA

NCBI chr13:62,487,257...62,504,657
Ensembl chr13:62,487,257...62,504,119

G

DNA primase subunit 1

decreases expression

Diquat results in decreased expression of PRIM1 mRNA

NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526

G

protein kinase cAMP-dependent type II regulatory subunit beta

decreases expression

Diquat results in decreased expression of PRKAR2B mRNA

NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933

G

protein kinase D3

decreases expression

Diquat results in decreased expression of PRKD3 mRNA

NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443

G

proline dehydrogenase

increases expression

Diquat results in increased expression of PRODH mRNA

NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305

G

prokineticin 1

decreases expression

Diquat results in decreased expression of PROK1 mRNA

NCBI chr 2:194,850,539...194,859,343
Ensembl chr 2:194,853,991...194,859,250

G

PROP paired-like homeobox 1

decreases response to substance
multiple interactions
affects response to substance

PROP1 gene mutant form results in decreased susceptibility to Diquat
PROP1 protein affects the reaction [Diquat affects the phosphorylation of MAPK9 protein]; PROP1 protein affects the reaction [Diquat results in decreased expression of MT1 mRNA]; PROP1 protein affects the reaction [Diquat results in decreased expression of MT2 mRNA]; PROP1 protein affects the reaction [Diquat results in increased cleavage of CASP9 protein]; PROP1 protein affects the reaction [Diquat results in increased expression of DDIT3 mRNA]; PROP1 protein affects the reaction [Diquat results in increased expression of DDIT3 protein]; PROP1 protein affects the reaction [Diquat results in increased expression of EGR1 mRNA]; PROP1 protein affects the reaction [Diquat results in increased expression of FOS mRNA]; PROP1 protein affects the reaction [Diquat results in increased expression of HMOX1 mRNA]; PROP1 protein affects the reaction [Diquat results in increased expression of NFE2L2 protein]; PROP1 protein affects the reaction [Diquat results in increased expression of NQO1 mRNA]; PROP1 protein affects the reaction [Diquat results in increased phosphorylation of AKT1 protein]
PROP1 protein affects the susceptibility to Diquat

PMID:19414510 PMID:20826540

NCBI chr10:35,271,959...35,274,434
Ensembl chr10:35,271,973...35,274,434

G

protein Z, vitamin K-dependent plasma glycoprotein

decreases expression

Diquat results in decreased expression of PROZ mRNA

NCBI chr16:76,450,013...76,463,558
Ensembl chr16:76,450,013...76,463,480

G

pre-mRNA processing factor 39

decreases expression

Diquat results in decreased expression of PRPF39 protein

NCBI chr 6:83,088,981...83,113,826
Ensembl chr 6:83,088,986...83,113,825

G

proline rich 15

increases expression

Diquat results in increased expression of PRR15 mRNA

NCBI chr 4:83,432,002...83,435,582
Ensembl chr 4:83,431,758...83,437,436

G

proline rich 15-like

decreases expression

Diquat results in decreased expression of PRR15L protein

NCBI chr10:81,916,491...81,922,454
Ensembl chr10:81,906,471...81,923,283

G

proline rich 5

increases expression
decreases expression

Diquat results in increased expression of PRR5 mRNA
Diquat results in decreased expression of PRR5 protein

NCBI chr 7:115,795,351...115,837,880
Ensembl chr 7:115,813,954...115,834,834

G

serine protease 35

decreases expression

Diquat results in decreased expression of PRSS35 mRNA

NCBI chr 8:87,714,449...87,731,009
Ensembl chr 8:87,714,966...87,731,009

G

peroxiredoxin like 2B

increases expression

Diquat results in increased expression of PRXL2B mRNA

NCBI chr 5:165,462,610...165,465,213

G

prosaposin

increases expression

Diquat results in increased expression of PSAP mRNA

NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498

G

phosphoserine aminotransferase 1

increases expression

Diquat results in increased expression of PSAT1 mRNA

NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682

G

proteasome 20S subunit beta 9

decreases expression

Diquat results in decreased expression of PSMB9 mRNA

NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512

G

proteasome 26S subunit, non-ATPase 11

increases expression

Diquat results in increased expression of PSMD11 mRNA

NCBI chr10:65,433,853...65,479,774
Ensembl chr10:65,433,853...65,479,766

G

prostaglandin-endoperoxide synthase 2

increases expression
multiple interactions

Diquat results in increased expression of PTGS2 protein
Meloxicam inhibits the reaction [Diquat results in increased expression of PTGS2 protein]; pifithrin inhibits the reaction [Diquat results in increased expression of PTGS2 protein]; SN50 peptide inhibits the reaction [Diquat results in increased expression of PTGS2 protein]

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

parathymosin

increases expression

Diquat results in increased expression of PTMS protein

NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009

G

protein tyrosine phosphatase, non-receptor type 7

decreases expression

Diquat results in decreased expression of PTPN7 mRNA

NCBI chr13:46,570,904...46,584,048
Ensembl chr13:46,571,712...46,583,308

G

protein tyrosine phosphatase, receptor type, C

decreases expression

Diquat results in decreased expression of PTPRC mRNA

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

G

protein tyrosine phosphatase, receptor type, Q

decreases expression

Diquat results in decreased expression of PTPRQ mRNA

NCBI chr 7:42,834,455...43,016,807
Ensembl chr 7:42,837,109...43,016,917

G

peroxisomal membrane protein 4

increases expression

Diquat results in increased expression of PXMP4 mRNA

NCBI chr 3:143,093,371...143,110,620
Ensembl chr 3:143,093,018...143,110,651

G

R3H domain and coiled-coil containing 1

decreases expression

Diquat results in decreased expression of R3HCC1 protein

NCBI chr15:44,774,552...44,781,864
Ensembl chr15:44,774,554...44,791,800

G

RAB36, member RAS oncogene family

decreases expression

Diquat results in decreased expression of RAB36 mRNA

NCBI chr20:13,606,700...13,624,304
Ensembl chr20:13,608,136...13,624,170

G

RAB5B, member RAS oncogene family

decreases expression

Diquat results in decreased expression of RAB5B protein

NCBI chr 7:1,109,449...1,128,348
Ensembl chr 7:1,109,454...1,128,268

G

RAB5 interacting factor

increases expression

Diquat results in increased expression of RAB5IF mRNA

NCBI chr 3:145,357,990...145,368,012
Ensembl chr 3:145,357,861...145,368,012

G

RAB, member of RAS oncogene family like 2

decreases expression

Diquat results in decreased expression of RABL2 protein

NCBI chr 7:120,652,175...120,660,906
Ensembl chr 7:120,652,175...120,660,783

G

RAB, member RAS oncogene family-like 6

decreases expression

Diquat results in decreased expression of RABL6 protein

NCBI chr 3:8,402,666...8,428,588
Ensembl chr 3:8,402,672...8,428,611

G

Rac family small GTPase 2

decreases expression

Diquat results in decreased expression of RAC2 mRNA

NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720

G

RAN binding protein 1

increases expression

Diquat results in increased expression of RANBP1 protein

NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838

G

Rap guanine nucleotide exchange factor 5

decreases expression

Diquat results in decreased expression of RAPGEF5 mRNA

NCBI chr 6:138,445,184...138,679,943
Ensembl chr 6:138,437,991...138,679,936

G

RAS protein activator like 3

decreases expression

Diquat results in decreased expression of RASAL3 mRNA

NCBI chr 7:11,396,554...11,411,347
Ensembl chr 7:11,396,090...11,411,465

G

RasGEF domain family, member 1B

increases expression

Diquat results in increased expression of RASGEF1B mRNA

NCBI chr14:9,859,512...10,380,044
Ensembl chr14:9,860,247...10,379,741

G

RAS-like, family 10, member B

increases expression

Diquat results in increased expression of RASL10B mRNA

NCBI chr10:68,209,761...68,222,118
Ensembl chr10:68,210,275...68,220,376

G

RAS-like, family 12

increases expression

Diquat results in increased expression of RASL12 mRNA

NCBI chr 8:65,917,840...65,931,885
Ensembl chr 8:65,917,840...65,932,741

G

RNA binding protein, mRNA processing factor

increases expression

Diquat results in increased expression of RBPMS mRNA

NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426

G

regulator of calcineurin 1

increases expression

Diquat results in increased expression of RCAN1 mRNA

NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045

G

reticulocalbin 3

decreases expression

Diquat results in decreased expression of RCN3 mRNA

NCBI chr 1:95,564,503...95,573,762
Ensembl chr 1:95,564,380...95,573,725

G

receptor accessory protein 5

increases expression

Diquat results in increased expression of REEP5 protein

NCBI chr18:25,945,375...25,983,271
Ensembl chr18:25,945,381...25,976,509

G

receptor accessory protein 6

increases expression

Diquat results in increased expression of REEP6 mRNA; Diquat results in increased expression of REEP6 protein

NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597

G

RELA proto-oncogene, NF-kB subunit

increases expression

Diquat results in increased expression of RELA mRNA; Diquat results in increased expression of RELA protein

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

reticulophagy regulator 1

decreases expression

Diquat results in decreased expression of RETREG1 protein

NCBI chr 2:76,335,609...76,474,817
Ensembl chr 2:76,335,609...76,493,898

G

retinol saturase

increases expression

Diquat results in increased expression of RETSAT mRNA

NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310

G

similar to RIKEN cDNA 3110043O21

increases expression

Diquat results in increased expression of C9ORF72 protein

NCBI chr 5:49,766,340...49,791,434
Ensembl chr 5:49,766,325...49,791,408

G

regulator of G-protein signaling 20

increases expression

Diquat results in increased expression of RGS20 mRNA

NCBI chr 5:14,484,436...14,614,317
Ensembl chr 5:14,534,775...14,614,084

G

regulator of G-protein signaling 4

increases expression

Diquat results in increased expression of RGS4 mRNA

NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068

G

rhodopsin

decreases expression

Diquat results in decreased expression of RHO protein

NCBI chr 4:148,975,597...148,988,693
Ensembl chr 4:148,980,611...148,985,773

G

ras homolog family member D

increases expression

Diquat results in increased expression of RHOD mRNA

NCBI chr 1:201,708,699...201,724,405
Ensembl chr 1:201,708,699...201,722,632

G

ripply transcriptional repressor 1

increases expression

Diquat results in increased expression of RIPPLY1 mRNA

NCBI chr X:103,436,731...103,440,904
Ensembl chr X:103,436,729...103,443,349

G

ribonuclease A family member 4

increases expression

Diquat results in increased expression of RNASE4 protein

NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117

G

ribonuclease A family member 6

decreases expression

Diquat results in decreased expression of RNASE6 mRNA

NCBI chr15:24,354,305...24,357,289
Ensembl chr15:24,354,303...24,357,328

G

Rho family GTPase 3

increases expression

Diquat results in increased expression of RND3 mRNA

NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327

G

ring finger protein 126

decreases expression

Diquat results in decreased expression of RNF126 protein

NCBI chr 7:9,939,359...9,946,963
Ensembl chr 7:9,938,229...9,946,738

G

ring finger protein 180

decreases expression

Diquat results in decreased expression of RNF180 mRNA

NCBI chr 2:36,330,285...36,511,168
Ensembl chr 2:36,330,292...36,512,614

G

ring finger protein 24

decreases expression

Diquat results in decreased expression of RNF24 mRNA

NCBI chr 3:118,520,459...118,575,213
Ensembl chr 3:118,525,349...118,541,080

G

roundabout guidance receptor 3

decreases expression

Diquat results in decreased expression of ROBO3 mRNA

NCBI chr 8:37,133,542...37,151,674
Ensembl chr 8:37,133,916...37,151,315

G

ribosomal protein L17

increases expression

Diquat results in increased expression of RPL17 protein

NCBI chr18:68,581,141...68,584,253
Ensembl chr18:68,581,098...68,584,253

G

ribosomal protein L37

decreases expression

Diquat results in decreased expression of RPL37 protein

NCBI chr 2:54,215,469...54,217,429
Ensembl chr 2:54,215,469...54,217,442

G

ribosomal protein L37A

decreases expression

Diquat results in decreased expression of RPL37A protein

NCBI chr 9:74,298,843...74,300,926

G

ribosomal protein S26

decreases expression

Diquat results in decreased expression of RPS26 protein

NCBI chr 7:1,057,332...1,058,882

G

RNA pseudouridine synthase D4

increases expression

Diquat results in increased expression of RPUSD4 protein

NCBI chr 8:33,617,384...33,626,873
Ensembl chr 8:33,617,379...33,626,873

G

radical S-adenosyl methionine domain containing 2

decreases expression

Diquat results in decreased expression of RSAD2 mRNA

NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699

G

RT1 class II, locus Ba

decreases expression

Diquat results in decreased expression of H2-AA mRNA

NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744

G

RT1 class II, locus Bb

decreases expression

Diquat results in decreased expression of H2-AB1 mRNA

NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597

G

RT1 class II, locus Db1

decreases expression

Diquat results in decreased expression of H2-EB1 mRNA; Diquat results in decreased expression of H2-EB1 protein

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

G

RT1 class II, locus DMa

decreases expression

Diquat results in decreased expression of H2-DMA mRNA

NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432

G

RT1 class II, locus DOa

decreases expression

Diquat results in decreased expression of H2-OA mRNA

NCBI chr20:4,753,587...4,756,590
Ensembl chr20:4,753,598...4,756,577

G

rhotekin

increases expression

Diquat results in increased expression of RTKN mRNA

NCBI chr 4:115,640,813...115,657,952
Ensembl chr 4:115,640,774...115,657,952

G

receptor (chemosensory) transporter protein 4

decreases expression

Diquat results in decreased expression of RTP4 mRNA

NCBI chr11:77,237,341...77,249,194
Ensembl chr11:77,238,216...77,335,437

G

RUN domain containing 3A

increases expression

Diquat results in increased expression of RUNDC3A mRNA

NCBI chr10:87,352,624...87,361,767
Ensembl chr10:87,352,646...87,361,765

G

RING1 and YY1 binding protein

increases expression

Diquat results in increased expression of RYBP protein

NCBI chr 4:132,876,260...132,928,328
Ensembl chr 4:132,876,361...132,928,316

G

S100 calcium binding protein A10

increases expression

Diquat results in increased expression of S100A10 mRNA

NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661

G

serum amyloid A4

increases expression

Diquat results in increased expression of SAA4 mRNA

NCBI chr 1:97,247,580...97,251,882

G

secretion associated, Ras related GTPase 1A

increases expression

Diquat results in increased expression of SAR1A protein

NCBI chr20:29,623,529...29,635,935
Ensembl chr20:29,623,553...29,635,935

G

SAM and SH3 domain containing 3

decreases expression

Diquat results in decreased expression of SASH3 mRNA

NCBI chr X:127,326,815...127,341,521
Ensembl chr X:127,326,859...127,341,519

G

spermidine/spermine N1-acetyl transferase 1

increases expression

Diquat results in increased expression of SAT1 mRNA

NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813

G

SAYSVFN motif domain containing 1

decreases expression

Diquat results in decreased expression of SAYSD1 protein

NCBI chr15:4,224,129...4,229,798

G

strawberry notch homolog 2

increases expression

Diquat results in increased expression of SBNO2 mRNA

NCBI chr 7:9,605,572...9,649,529
Ensembl chr 7:9,605,627...9,649,527

G

suppressor of cancer cell invasion

decreases expression

Diquat results in decreased expression of SCAI mRNA

NCBI chr 3:22,813,283...22,925,337
Ensembl chr 3:22,819,574...22,925,363

G

secretory carrier membrane protein 4

decreases expression

Diquat results in decreased expression of SCAMP4 protein

NCBI chr 7:9,101,504...9,113,929
Ensembl chr 7:9,101,489...9,113,967

G

sodium channel epithelial 1 subunit beta

increases expression

Diquat results in increased expression of SCNN1B protein

NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451

G

signal peptide, CUB domain and EGF like domain containing 1

decreases expression

Diquat results in decreased expression of SCUBE1 mRNA

NCBI chr 7:114,759,016...114,880,995
Ensembl chr 7:114,759,010...114,880,940

G

syndecan 3

decreases expression

Diquat results in decreased expression of SDC3 mRNA

NCBI chr 5:142,965,659...142,998,390
Ensembl chr 5:142,965,591...142,996,480

G

stromal cell-derived factor 2-like 1

decreases expression

Diquat results in decreased expression of SDF2L1 protein

NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902

G

succinate dehydrogenase complex subunit D

decreases expression

Diquat results in decreased expression of SDHD protein

NCBI chr 8:50,944,702...50,954,298
Ensembl chr 8:50,944,704...50,954,238

G

SEC14-like lipid binding 4

increases expression

Diquat results in increased expression of SEC14L4 mRNA

NCBI chr14:78,912,750...78,928,799
Ensembl chr14:78,912,750...78,956,099

G

SEC61 translocon subunit alpha 2

decreases expression

Diquat results in decreased expression of SEC61A2 protein

NCBI chr17:72,407,574...72,445,630
Ensembl chr17:72,407,671...72,434,494

G

SECIS binding protein 2-like

decreases expression

Diquat results in decreased expression of SECISBP2L protein

NCBI chr 3:112,989,613...113,036,060
Ensembl chr 3:112,991,908...113,035,884

G

selenoprotein O

decreases expression

Diquat results in decreased expression of SELENOO protein

NCBI chr 7:120,167,913...120,178,806
Ensembl chr 7:120,167,913...120,178,805

G

selectin P ligand

decreases expression

Diquat results in decreased expression of SELPLG mRNA

NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585

G

semaphorin 3A

decreases expression

Diquat results in decreased expression of SEMA3A mRNA

NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432

G

semaphorin 3D

decreases expression

Diquat results in decreased expression of SEMA3D mRNA

NCBI chr 4:22,316,769...22,505,930
Ensembl chr 4:22,316,779...22,505,930

G

SUMO specific peptidase 3

increases expression

Diquat results in increased expression of SENP3 protein

NCBI chr10:54,390,698...54,399,590
Ensembl chr10:54,390,694...54,399,593

G

SUMO specific peptidase 7

decreases expression

Diquat results in decreased expression of SENP7 protein

NCBI chr11:44,423,733...44,584,129
Ensembl chr11:44,423,735...44,564,711

G

serpin family A member 3N

increases expression

Diquat results in increased expression of SERPINA3N mRNA; Diquat results in increased expression of SERPINA3N protein

NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433

G

serpin family B member 8

increases expression

Diquat results in increased expression of SERPINB8 mRNA

NCBI chr13:23,626,936...23,650,277
Ensembl chr13:23,626,945...23,650,835

G

serpin family E member 1

increases expression

Diquat results in increased expression of SERPINE1 mRNA

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

G

serpin family G member 1

decreases expression

Diquat results in decreased expression of SERPING1 mRNA

NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034

G

secreted frizzled-related protein 4

decreases expression

Diquat results in decreased expression of SFRP4 mRNA

NCBI chr17:45,278,867...45,330,806
Ensembl chr17:45,234,097...45,330,736

G

serum/glucocorticoid regulated kinase 2

increases expression

Diquat results in increased expression of SGK2 protein

NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480

G

SH3 domain and tetratricopeptide repeats 2

increases expression

Diquat results in increased expression of SH3TC2 mRNA

NCBI chr18:55,416,383...55,477,419
Ensembl chr18:55,416,413...55,483,083

G

shisa family member 4

increases expression

Diquat results in increased expression of SHISA4 mRNA

NCBI chr13:46,799,735...46,803,816
Ensembl chr13:46,799,772...46,803,998

G

shortage in chiasmata 1

decreases expression

Diquat results in decreased expression of SHOC1 mRNA

NCBI chr 5:73,864,423...73,956,487
Ensembl chr 5:73,866,334...73,956,444

G

SIK family kinase 3

increases expression

Diquat results in increased expression of SIK3 protein

NCBI chr 8:46,312,253...46,522,444
Ensembl chr 8:46,311,989...46,522,444

G

signal-induced proliferation-associated 1 like 3

decreases expression

Diquat results in decreased expression of SIPA1L3 protein

NCBI chr 1:84,618,714...84,825,956
Ensembl chr 1:84,618,719...84,703,802

G

SLAM family member 8

decreases expression

Diquat results in decreased expression of SLAMF8 mRNA

NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211

G

SLAM family member 9

decreases expression

Diquat results in decreased expression of SLAMF9 mRNA

NCBI chr13:84,941,896...84,944,749
Ensembl chr13:84,941,982...84,944,748

G

solute carrier family 10 member 2

increases expression

Diquat results in increased expression of SLC10A2 protein

NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475

G

solute carrier family 12 member 2

decreases expression

Diquat results in decreased expression of SLC12A2 mRNA

NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440

G

solute carrier family 13 member 2

increases expression

Diquat results in increased expression of SLC13A2 mRNA

NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127

G

solute carrier family 14 member 1 (Kidd blood group)

decreases expression

Diquat results in decreased expression of SLC14A1 mRNA

NCBI chr18:71,565,453...71,608,807
Ensembl chr18:71,565,454...71,595,146

G

solute carrier family 16 member 1

increases expression

Diquat results in increased expression of SLC16A1 mRNA; Diquat results in increased expression of SLC16A1 protein

NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611

G

solute carrier family 16 member 2

decreases expression

Diquat results in decreased expression of SLC16A2 protein

NCBI chr X:68,725,365...68,848,572
Ensembl chr X:68,723,261...68,848,771

G

solute carrier family 16, member 4

decreases expression

Diquat results in decreased expression of SLC16A4 protein

NCBI chr 2:194,911,075...194,933,162
Ensembl chr 2:194,911,236...194,933,117

G

solute carrier family 16, member 6

increases expression

Diquat results in increased expression of SLC16A6 mRNA

NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779

G

solute carrier family 17 member 3

decreases expression

Diquat results in decreased expression of SLC17A3 mRNA

NCBI chr17:41,270,804...41,300,132
Ensembl chr17:41,270,812...41,295,256

G

solute carrier family 17, member 4

decreases expression

Diquat results in decreased expression of SLC17A4 mRNA

NCBI chr17:41,201,546...41,218,752
Ensembl chr17:41,207,552...41,218,752

G

solute carrier family 17 member 9

increases expression

Diquat results in increased expression of SLC17A9 mRNA

NCBI chr 3:167,839,246...167,857,462
Ensembl chr 3:167,839,385...167,855,985

G

solute carrier family 19 member 1

increases expression

Diquat results in increased expression of SLC19A1 mRNA

NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972

G

solute carrier family 20 member 1

increases expression

Diquat results in increased expression of SLC20A1 mRNA

NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051

G

solute carrier family 22 member 22

decreases expression

Diquat results in decreased expression of SLC22A22 mRNA

NCBI chr 7:88,720,425...88,750,111
Ensembl chr 7:88,720,427...88,750,111

G

solute carrier family 22 member 3

increases expression

Diquat results in increased expression of SLC22A3 mRNA

NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612

G

solute carrier family 22 member 7

decreases expression

Diquat results in decreased expression of SLC22A7 mRNA

NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921

G

solute carrier family 23, member 3

increases expression

Diquat results in increased expression of SLC23A3 mRNA

NCBI chr 9:76,622,621...76,633,188
Ensembl chr 9:76,622,800...76,631,366

G

solute carrier family 25 member 20

increases expression

Diquat results in increased expression of SLC25A20 mRNA

NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512

G

solute carrier family 25 member 22

increases expression

Diquat results in increased expression of SLC25A22 mRNA

NCBI chr 1:196,528,471...196,536,398
Ensembl chr 1:196,528,472...196,536,331

G

solute carrier family 25 member 25

increases expression

Diquat results in increased expression of SLC25A25 mRNA

NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216

G

solute carrier family 25, member 46

increases expression

Diquat results in increased expression of SLC25A46 protein

NCBI chr18:23,215,954...23,244,917
Ensembl chr18:23,215,962...23,244,314

G

solute carrier family 26 member 6

increases expression

Diquat results in increased expression of SLC26A6 mRNA

NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778

G

solute carrier family 27 member 1

increases expression

Diquat results in increased expression of SLC27A1 mRNA

NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063

G

solute carrier family 2 member 13

decreases expression

Diquat results in decreased expression of SLC2A13 protein

NCBI chr 7:122,399,329...122,726,605
Ensembl chr 7:122,399,330...122,726,605

G

solute carrier family 2 member 2

increases expression

Diquat results in increased expression of SLC2A2 protein

NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933

G

solute carrier family 30 member 8

increases expression

Diquat results in increased expression of SLC30A8 mRNA

NCBI chr 7:83,591,993...83,627,786
Ensembl chr 7:83,591,993...83,626,305

G

solute carrier family 35, member F2

decreases expression

Diquat results in decreased expression of SLC35F2 protein

NCBI chr 8:54,159,970...54,203,614
Ensembl chr 8:54,159,970...54,203,612

G

solute carrier family 38, member 3

increases expression

Diquat results in increased expression of SLC38A3 mRNA

NCBI chr 8:108,323,889...108,339,959
Ensembl chr 8:108,323,894...108,339,988

G

solute carrier family 39 member 14

increases expression

Diquat results in increased expression of SLC39A14 protein

PMID:36851058 PMID:38128689

NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524

G

solute carrier family 39 member 8

increases expression

Diquat results in increased expression of SLC39A8 protein

NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129

G

solute carrier family 3 member 2

increases expression

Diquat results in increased expression of SLC3A2 protein

NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931

G

solute carrier family 40 member 1

decreases expression

Diquat results in decreased expression of SLC40A1 mRNA

NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481

G

solute carrier family 45, member 3

increases expression

Diquat results in increased expression of SLC45A3 mRNA

NCBI chr13:43,407,293...43,427,588
Ensembl chr13:43,407,293...43,427,588

G

solute carrier family 48 member 1

increases expression

Diquat results in increased expression of SLC48A1 mRNA

NCBI chr 7:128,915,136...128,923,929
Ensembl chr 7:128,915,195...128,923,024

G

solute carrier family 4 member 11

decreases expression

Diquat results in decreased expression of SLC4A11 mRNA

NCBI chr 3:117,900,223...117,912,787
Ensembl chr 3:117,900,223...117,912,674

G

solute carrier family 4 member 2

decreases expression

Diquat results in decreased expression of SLC4A2 protein

NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965

G

solute carrier family 51 member A

increases expression

Diquat results in increased expression of SLC51A protein

NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485

G

solute carrier family 5 member 10

increases expression

Diquat results in increased expression of SLC5A10 mRNA

NCBI chr10:46,352,060...46,400,795
Ensembl chr10:46,352,061...46,399,811

G

solute carrier family 5 member 2

decreases expression

Diquat results in decreased expression of SLC5A2 protein

NCBI chr 1:182,847,185...182,853,309
Ensembl chr 1:182,847,106...182,853,306

G

solute carrier family 6 member 13

increases expression

Diquat results in increased expression of SLC6A13 mRNA

NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152

G

solute carrier family 6 member 15

decreases expression

Diquat results in decreased expression of SLC6A15 mRNA

NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239

G

solute carrier family 6 member 18

increases expression

Diquat results in increased expression of SLC6A18 mRNA

NCBI chr 1:29,607,288...29,621,925
Ensembl chr 1:29,608,077...29,621,925

G

solute carrier family 6 member 4

increases expression

Diquat results in increased expression of SLC6A4 mRNA

NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384

G

solute carrier family 6 member 8

decreases expression

Diquat results in decreased expression of SLC6A8 protein

NCBI chr X:151,384,675...151,393,979
Ensembl chr X:151,384,675...151,393,979

G

solute carrier family 7 member 11

increases expression

Diquat results in increased expression of SLC7A11 mRNA

NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536

G

solute carrier family 7 member 13

increases expression
decreases expression

Diquat results in increased expression of SLC7A13 protein
Diquat results in decreased expression of SLC7A13 mRNA

NCBI chr 5:33,277,400...33,298,186
Ensembl chr 5:33,277,416...33,298,092

G

solute carrier family 9 member A8

decreases expression

Diquat results in decreased expression of SLC9A8 mRNA

NCBI chr 3:156,147,855...156,198,497
Ensembl chr 3:156,148,104...156,198,471

G

schlafen family member 5

decreases expression

Diquat results in decreased expression of SLFN5 mRNA

NCBI chr10:67,881,068...67,895,013
Ensembl chr10:67,880,009...67,893,109

G

SLIT and NTRK-like family, member 6

decreases expression

Diquat results in decreased expression of SLITRK6 mRNA

NCBI chr15:87,563,506...87,570,125
Ensembl chr15:87,563,322...87,570,393

G

SWI/SNF related BAF chromatin remodeling complex subunit E1

decreases expression

Diquat results in decreased expression of SMARCE1 protein

NCBI chr10:84,159,270...84,180,547
Ensembl chr10:84,159,275...84,179,989

G

sperm mitochondria-associated cysteine-rich protein

decreases expression

Diquat results in decreased expression of SMCP mRNA

NCBI chr 2:178,160,948...178,165,951
Ensembl chr 2:178,160,127...178,166,001

G

SMG5 nonsense mediated mRNA decay factor

decreases expression

Diquat results in decreased expression of SMG5 protein

NCBI chr 2:173,804,987...173,832,102
Ensembl chr 2:173,805,019...173,832,102

G

sphingomyelin phosphodiesterase 5

increases expression

Diquat results in increased expression of SMPD5 mRNA

NCBI chr 7:108,009,182...108,011,767
Ensembl chr 7:108,009,173...108,011,763

G

synaptosome associated protein 47

decreases expression

Diquat results in decreased expression of SNAP47 protein

NCBI chr10:44,192,886...44,234,435
Ensembl chr10:44,191,218...44,234,424

G

small nuclear ribonucleoprotein polypeptide F

increases expression

Diquat results in increased expression of SNRPF protein

NCBI chr 7:28,130,427...28,137,129
Ensembl chr 7:28,130,427...28,137,129

G

syntrophin, alpha 1

increases expression

Diquat results in increased expression of SNTA1 mRNA

NCBI chr 3:142,876,285...142,906,737
Ensembl chr 3:142,876,296...142,906,709

G

sorting nexin 31

decreases expression

Diquat results in decreased expression of SNX31 mRNA

NCBI chr 7:67,676,514...67,776,925
Ensembl chr 7:67,676,524...67,732,086

G

suppressor of cytokine signaling 3

increases expression

Diquat results in increased expression of SOCS3 mRNA

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

G

superoxide dismutase 1

multiple interactions
decreases activity
decreases expression

GPX1 protein affects the reaction [Diquat results in decreased activity of SOD1 protein]; GPX1 protein affects the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in decreased activity of SOD1 protein]]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in decreased activity of SOD1 protein]
Diquat results in decreased expression of SOD1 mRNA

PMID:7676460 PMID:11672444

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

multiple interactions
increases activity
increases expression

GPX1 protein affects the reaction [Diquat results in increased activity of SOD2 protein]; GPX1 protein affects the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in increased activity of SOD2 protein]]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in increased activity of SOD2 protein]
Diquat results in increased expression of SOD2 protein

PMID:11672444 PMID:29484840

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

sosondowah ankyrin repeat domain family member B

increases expression

Diquat results in increased expression of SOWAHB mRNA

NCBI chr14:15,029,203...15,033,038
Ensembl chr14:15,029,395...15,031,698

G

SRY-box transcription factor 17

decreases localization

Diquat results in decreased localization of SOX17 protein

NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228

G

SRY-box transcription factor 9

increases expression

Diquat results in increased expression of SOX9 mRNA

NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994

G

SP100 nuclear antigen

decreases expression

Diquat results in decreased expression of SP100 mRNA

NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034

G

sperm acrosome associated 5

decreases expression

Diquat results in decreased expression of SPACA5 protein

NCBI chr X:918,817...922,000
Ensembl chr X:918,817...922,049

G

spermatogenesis associated 2

decreases expression

Diquat results in decreased expression of SPATA2 protein

NCBI chr 3:156,202,962...156,213,283
Ensembl chr 3:156,202,967...156,211,705

G

spermatogenesis and centriole associated 1

increases expression

Diquat results in increased expression of SPATC1 mRNA

NCBI chr 7:107,980,857...108,007,716
Ensembl chr 7:107,983,796...108,007,479

G

spermatogenesis associated, serine-rich 2-like

decreases expression

Diquat results in decreased expression of SPATS2L mRNA

NCBI chr 9:59,319,949...59,493,864
Ensembl chr 9:59,320,276...59,493,967

G

spindle apparatus coiled-coil protein 1

decreases expression

Diquat results in decreased expression of SPDL1 mRNA

NCBI chr10:19,269,125...19,294,213
Ensembl chr10:19,269,127...19,294,127

G

sperm flagellar 2

decreases expression

Diquat results in decreased expression of SPEF2 mRNA

NCBI chr 2:58,512,489...58,694,718
Ensembl chr 2:58,512,489...58,694,664

G

serine peptidase inhibitor, Kazal type 1

increases expression

Diquat results in increased expression of SPINK1 mRNA

NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642

G

SPNS lysolipid transporter 2, sphingosine-1-phosphate

increases expression

Diquat results in increased expression of SPNS2 mRNA

NCBI chr10:57,067,348...57,105,969
Ensembl chr10:57,066,897...57,105,957

G

sequestosome 1

increases expression

Diquat results in increased expression of SQSTM1 mRNA

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

steroid 5 alpha-reductase 2

decreases expression

Diquat results in decreased expression of SRD5A2 mRNA

NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112

G

sushi-repeat-containing protein, X-linked

decreases expression

Diquat results in decreased expression of SRPX mRNA

NCBI chr X:12,676,984...12,751,296
Ensembl chr X:12,566,645...12,747,882

G

sushi-repeat-containing protein, X-linked 2

decreases expression

Diquat results in decreased expression of SRPX2 mRNA

NCBI chr X:97,106,455...97,132,197
Ensembl chr X:97,106,561...97,132,195

G

serine and arginine rich splicing factor 3

increases expression

Diquat results in increased expression of SRSF3 protein

NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078

G

sulfiredoxin 1

increases expression

Diquat results in increased expression of SRXN1 mRNA

PMID:21172416 PMID:36851058

NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448

G

single stranded DNA binding protein 3

decreases expression

Diquat results in decreased expression of SSBP3 protein

NCBI chr 5:121,691,370...121,828,035
Ensembl chr 5:121,691,393...121,827,992

G

slingshot protein phosphatase 2

increases expression

Diquat results in increased expression of SSH2 protein

NCBI chr10:62,057,400...62,309,328
Ensembl chr10:62,057,044...62,306,563

G

SSU72 homolog, RNA polymerase II CTD phosphatase

decreases expression

Diquat results in decreased expression of SSU72 protein

NCBI chr 5:166,312,267...166,343,432
Ensembl chr 5:166,313,650...166,343,429

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

decreases expression

Diquat results in decreased expression of ST8SIA1 mRNA

NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708

G

signal transducer and activator of transcription 3

increases expression

Diquat results in increased expression of STAT3 mRNA

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

G

stanniocalcin 2

increases expression

Diquat results in increased expression of STC2 mRNA

NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973

G

STEAP3 metalloreductase

decreases expression

Diquat results in decreased expression of STEAP3 protein

NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519

G

STIL, centriolar assembly protein

decreases expression

Diquat results in decreased expression of STIL mRNA

NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730

G

serine/threonine kinase 40

increases expression

Diquat results in increased expression of STK40 mRNA

NCBI chr 5:138,380,049...138,417,802
Ensembl chr 5:138,381,159...138,417,796

G

sperm-tail PG-rich repeat containing 3

decreases expression

Diquat results in decreased expression of STPG3 mRNA

NCBI chr 3:8,028,122...8,030,546
Ensembl chr 3:8,028,131...8,034,601

G

STRA6-like

increases expression

Diquat results in increased expression of STRA6L mRNA

NCBI chr 5:60,106,949...60,147,546
Ensembl chr 5:60,107,085...60,147,539

G

syntaxin 6

decreases expression

Diquat results in decreased expression of STX6 protein

NCBI chr13:67,332,329...67,378,580
Ensembl chr13:67,332,314...67,378,576

G

syntaxin binding protein 6

decreases expression

Diquat results in decreased expression of STXBP6 protein

NCBI chr 6:61,920,756...62,157,405
Ensembl chr 6:61,920,756...62,158,024

G

SURP and G patch domain containing 1

decreases expression

Diquat results in decreased expression of SUGP1 protein

NCBI chr16:19,352,659...19,383,533
Ensembl chr16:19,351,793...19,383,756

G

sushi domain containing 3

increases expression

Diquat results in increased expression of SUSD3 mRNA

NCBI chr17:15,400,845...15,417,851
Ensembl chr17:15,400,845...15,417,044

G

sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1

decreases expression

Diquat results in decreased expression of SVEP1 mRNA

NCBI chr 5:72,811,200...72,988,185
Ensembl chr 5:72,811,410...72,988,525

G

SVOP like

increases expression

Diquat results in increased expression of SVOPL mRNA

NCBI chr 4:66,697,550...66,751,699
Ensembl chr 4:66,698,177...66,758,978

G

spleen associated tyrosine kinase

decreases expression

Diquat results in decreased expression of SYK mRNA

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

G

synaptopodin 2

decreases expression

Diquat results in decreased expression of SYNPO2 mRNA

NCBI chr 2:211,217,099...211,371,267
Ensembl chr 2:211,216,783...211,371,267

G

synaptopodin 2-like

increases expression

Diquat results in increased expression of SYNPO2L mRNA

NCBI chr15:3,631,974...3,641,429
Ensembl chr15:3,631,834...3,641,429

G

synaptotagmin 15

decreases expression

Diquat results in decreased expression of SYT15 mRNA

NCBI chr16:9,532,478...9,543,288
Ensembl chr16:9,532,478...9,543,281

G

TGF-beta activated kinase 1/MAP3K7 binding protein 1

decreases expression

Diquat results in decreased expression of TAB1 protein

NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058

G

TGF-beta activated kinase 1/MAP3K7 binding protein 2

decreases expression

Diquat results in decreased expression of TAB2 protein

NCBI chr 1:2,375,026...2,425,115
Ensembl chr 1:2,375,490...2,424,756

G

TATA-box binding protein associated factor 4b

increases expression

Diquat results in increased expression of TAF4B protein

NCBI chr18:5,952,737...6,086,408
Ensembl chr18:5,952,769...6,068,307

G

transgelin 2

increases expression

Diquat results in increased expression of TAGLN2 mRNA

NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972

G

transport and golgi organization 6 homolog

decreases expression

Diquat results in decreased expression of TANGO6 protein

NCBI chr19:34,569,588...34,757,362
Ensembl chr19:34,569,635...34,754,639

G

Tarbp2 subunit of RISC loading complex

decreases expression

Diquat results in decreased expression of TARBP2 protein

NCBI chr 7:133,649,118...133,654,306
Ensembl chr 7:133,649,090...133,654,314

G

TatD DNase domain containing 1

decreases expression

Diquat results in decreased expression of TATDN1 protein

NCBI chr 7:90,449,979...90,481,000
Ensembl chr 7:90,441,079...90,481,133

G

TBC1 domain family, member 2B

decreases expression

Diquat results in decreased expression of TBC1D2B mRNA

NCBI chr 8:90,746,220...90,814,867
Ensembl chr 8:90,746,233...90,814,832

G

TBC1 domain family, member 5

decreases expression

Diquat results in decreased expression of TBC1D5 protein

NCBI chr 9:3,503,328...4,017,131
Ensembl chr 9:3,513,623...4,016,913

G

T-box transcription factor 10

decreases expression

Diquat results in decreased expression of TBX10 mRNA

NCBI chr 1:201,285,729...201,292,676
Ensembl chr 1:201,279,829...201,292,601

G

T-box transcription factor 2

increases expression

Diquat results in increased expression of TBX2 mRNA

NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529

G

tandem C2 domains, nuclear

decreases expression

Diquat results in decreased expression of TC2N mRNA

NCBI chr 6:120,761,112...120,856,835
Ensembl chr 6:120,761,119...120,849,326

G

T cell activation inhibitor, mitochondrial

decreases expression

Diquat results in decreased expression of TCAIM protein

NCBI chr 8:122,414,827...122,446,105
Ensembl chr 8:122,414,818...122,446,092

G

transcription factor 21

decreases expression

Diquat results in decreased expression of TCF21 mRNA

NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202

G

trichohyalin-like 1

increases expression

Diquat results in increased expression of TCHHL1 mRNA

NCBI chr 2:179,134,941...179,138,467
Ensembl chr 2:179,135,796...179,138,202

G

t-complex 11 like 2

decreases expression

Diquat results in decreased expression of TCP11L2 protein

NCBI chr 7:19,150,241...19,185,135
Ensembl chr 7:19,150,252...19,185,095

G

TEK receptor tyrosine kinase

decreases expression

Diquat results in decreased expression of TEK mRNA

NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804

G

terminal nucleotidyltransferase 5A

decreases expression

Diquat results in decreased expression of TENT5A mRNA

NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045

G

transferrin

increases expression

Diquat results in increased expression of TRF mRNA

NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511

G

transferrin receptor

increases expression
decreases expression

Diquat results in increased expression of TFRC mRNA
Diquat results in decreased expression of TFRC protein

PMID:21698372 PMID:38128689

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

G

transforming growth factor, beta induced

decreases expression

Diquat results in decreased expression of TGFBI mRNA

NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240

G

transglutaminase 7

decreases expression

Diquat results in decreased expression of TGM7 mRNA

NCBI chr 3:108,051,890...108,068,116
Ensembl chr 3:108,051,890...108,076,239

G

trans-golgi network protein 2

decreases expression

Diquat results in decreased expression of TGOLN2 protein

NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164

G

thrombomodulin

increases secretion
multiple interactions
increases expression

Diquat results in increased secretion of THBD protein modified form
THBD protein modified form inhibits the reaction [Diquat results in increased expression of and results in increased secretion of HMGB1 protein]; THBD protein modified form inhibits the reaction [Diquat results in increased expression of HMGB1 mRNA]; THBD protein modified form inhibits the reaction [Diquat results in increased expression of NFKB1 mRNA]; THBD protein modified form inhibits the reaction [Diquat results in increased expression of THBD mRNA]; THBD protein modified form inhibits the reaction [Diquat results in increased expression of THBD protein]; THBD protein modified form inhibits the reaction [Diquat results in increased secretion of IL1B protein]; THBD protein modified form inhibits the reaction [Diquat results in increased secretion of TNF protein]
Diquat results in increased expression of THBD mRNA; Diquat results in increased expression of THBD protein

NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193

G

thioesterase superfamily member 6

increases expression

Diquat results in increased expression of THEM6 mRNA; Diquat results in increased expression of THEM6 protein

NCBI chr 7:106,606,570...106,609,747
Ensembl chr 7:106,606,570...106,609,746

G

thymocyte selection associated family member 2

decreases expression

Diquat results in decreased expression of THEMIS2 protein

NCBI chr 5:144,991,110...145,006,362
Ensembl chr 5:144,991,112...145,006,400

G

thyroid hormone responsive

decreases expression

Diquat results in decreased expression of THRSP mRNA

NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075

G

Thy-1 cell surface antigen

decreases expression

Diquat results in decreased expression of THY1 mRNA; Diquat results in decreased expression of THY1 protein

NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659

G

TIAM Rac1 associated GEF 2

increases expression

Diquat results in increased expression of TIAM2 mRNA

NCBI chr 1:43,918,179...44,119,499
Ensembl chr 1:43,918,174...44,119,493

G

TIFA inhibitor

decreases expression

Diquat results in decreased expression of TIFAB mRNA

NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592

G

transketolase

increases expression

Diquat results in increased expression of TKT mRNA

NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698

G

TLE family member 5, transcriptional modulator

decreases expression

Diquat results in decreased expression of TLE5 protein

NCBI chr 7:8,143,357...8,150,295
Ensembl chr 7:8,143,357...8,150,113

G

tolloid-like 1

decreases expression

Diquat results in decreased expression of TLL1 mRNA

NCBI chr16:25,509,146...25,710,330
Ensembl chr16:25,509,146...25,709,543

G

transmembrane 6 superfamily member 2

increases expression

Diquat results in increased expression of TM6SF2 mRNA

NCBI chr16:19,344,218...19,351,431
Ensembl chr16:19,344,222...19,351,431

G

transmembrane BAX inhibitor motif containing 1

increases expression

Diquat results in increased expression of TMBIM1 protein

NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069

G

transmembrane and coiled-coil domains 3

decreases expression

Diquat results in decreased expression of TMCO3 mRNA

NCBI chr16:76,217,146...76,254,309
Ensembl chr16:76,217,201...76,254,107

G

transmembrane and coiled-coil domains 4

increases expression

Diquat results in increased expression of TMCO4 mRNA

NCBI chr 5:151,216,499...151,294,726
Ensembl chr 5:151,216,812...151,294,723

G

transmembrane protein 106B

increases expression

Diquat results in increased expression of TMEM106B protein

NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619

G

transmembrane protein 143

decreases expression

Diquat results in decreased expression of TMEM143 protein

NCBI chr 1:96,371,934...96,387,991
Ensembl chr 1:96,371,938...96,387,991

G

transmembrane protein 14A

decreases expression

Diquat results in decreased expression of TMEM14A mRNA

NCBI chr 9:23,640,594...23,652,379
Ensembl chr 9:23,733,039...23,734,463
Ensembl chr 9:23,733,039...23,734,463

G

transmembrane protein 151A

increases expression

Diquat results in increased expression of TMEM151A mRNA

NCBI chr 1:202,387,397...202,392,182
Ensembl chr 1:202,388,240...202,392,182

G

transmembrane protein 167B

decreases expression

Diquat results in decreased expression of TMEM167B protein

NCBI chr 2:196,194,355...196,198,134
Ensembl chr 2:196,192,185...196,198,158
Ensembl chr20:196,192,185...196,198,158

G

transmembrane protein 171

increases expression

Diquat results in increased expression of TMEM171 mRNA

NCBI chr 2:30,035,278...30,045,996
Ensembl chr 2:30,035,278...30,045,049

G

transmembrane protein 201

decreases expression

Diquat results in decreased expression of TMEM201 protein

NCBI chr 5:160,166,240...160,188,874
Ensembl chr 5:160,166,427...160,188,843

G

transmembrane protein 204

decreases expression

Diquat results in decreased expression of TMEM204 mRNA

NCBI chr10:14,076,518...14,104,849
Ensembl chr10:14,076,519...14,101,920

G

transmembrane protein 205

increases expression

Diquat results in increased expression of TMEM205 mRNA

NCBI chr 8:20,452,092...20,458,011
Ensembl chr 8:20,452,092...20,457,828

G

transmembrane protein 229B

decreases expression

Diquat results in decreased expression of TMEM229B mRNA

NCBI chr 6:97,771,645...97,819,582
Ensembl chr 6:97,775,332...97,819,489

G

transmembrane protein 230

increases expression

Diquat results in increased expression of TMEM230 protein

NCBI chr 3:119,473,109...119,497,617
Ensembl chr 3:119,480,735...119,497,614

G

transmembrane protein 253

increases expression

Diquat results in increased expression of TMEM253 mRNA

NCBI chr15:24,706,517...24,709,107
Ensembl chr15:24,706,529...24,708,625

G

transmembrane protein 37

increases expression

Diquat results in increased expression of TMEM37 mRNA

NCBI chr13:31,184,322...31,191,477
Ensembl chr13:31,171,355...31,191,077

G

transmembrane protein 51

increases expression

Diquat results in increased expression of TMEM51 protein

NCBI chr 5:154,325,853...154,375,882
Ensembl chr 5:154,325,856...154,375,882

G

transmembrane protein 52

increases expression

Diquat results in increased expression of TMEM52 mRNA

NCBI chr 5:166,048,669...166,050,423
Ensembl chr 5:166,046,565...166,050,433

G

transmembrane protein 53

increases expression

Diquat results in increased expression of TMEM53 mRNA

NCBI chr 5:130,721,780...130,737,692
Ensembl chr 5:130,721,659...130,737,692

G

transmembrane protein 71

decreases expression

Diquat results in decreased expression of TMEM71 mRNA

NCBI chr 7:98,276,975...98,323,161
Ensembl chr 7:98,276,975...98,315,858

G

transmembrane inner ear

increases expression

Diquat results in increased expression of TMIE mRNA

NCBI chr 8:110,849,713...110,864,803
Ensembl chr 8:110,850,034...110,864,803

G

tenascin C

decreases expression

Diquat results in decreased expression of TNC mRNA

NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624

G

tumor necrosis factor

multiple interactions
increases expression
increases secretion

pifithrin inhibits the reaction [Diquat results in increased expression of TNF protein]; SN50 peptide inhibits the reaction [Diquat results in increased expression of TNF protein]; THBD protein modified form inhibits the reaction [Diquat results in increased secretion of TNF protein]

PMID:29484840 PMID:37277018

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF alpha induced protein 2

decreases expression

Diquat results in decreased expression of TNFAIP2 protein

NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914

G

TNF receptor superfamily member 11A

decreases expression

Diquat results in decreased expression of TNFRSF11A mRNA

NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695

G

TNF receptor superfamily member 12A

increases expression

Diquat results in increased expression of TNFRSF12A mRNA

NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045

G

TNFAIP3 interacting protein 3

decreases expression

Diquat results in decreased expression of TNIP3 mRNA

NCBI chr 4:94,867,258...94,908,780
Ensembl chr 4:94,811,097...94,907,605

G

tenascin N

decreases expression

Diquat results in decreased expression of TNN mRNA

NCBI chr13:72,319,160...72,386,362
Ensembl chr13:72,319,155...72,408,156

G

DNA topoisomerase II alpha

decreases expression

Diquat results in decreased expression of TOP2A mRNA

NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874

G

torsin family 1, member B

decreases expression

Diquat results in decreased expression of TOR1B protein

NCBI chr 3:14,243,181...14,249,279
Ensembl chr 3:14,243,243...14,249,272

G

TOX high mobility group box family member 2

increases expression

Diquat results in increased expression of TOX2 mRNA

NCBI chr 3:151,853,294...151,980,086
Ensembl chr 3:151,853,294...151,980,749

G

tumor protein p53

multiple interactions

Diquat results in increased expression of and affects the localization of TP53 protein; pifithrin inhibits the reaction [Diquat results in increased expression of and affects the localization of TP53 protein]; SN50 peptide inhibits the reaction [Diquat results in increased expression of and affects the localization of TP53 protein]

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tropomyosin 4

increases expression

Diquat results in increased expression of TPM4 protein

NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984

G

TPX2, microtubule nucleation factor

decreases expression

Diquat results in decreased expression of TPX2 mRNA

NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468

G

tetratricopeptide repeat and ankyrin repeat containing 1

decreases expression

Diquat results in decreased expression of TRANK1 protein

NCBI chr 8:111,275,973...111,355,491
Ensembl chr 8:111,276,354...111,355,092

G

triadin

decreases expression

Diquat results in decreased expression of TRDN mRNA

NCBI chr 1:23,955,651...24,410,494
Ensembl chr 1:23,955,651...24,410,595

G

tribbles pseudokinase 2

decreases expression

Diquat results in decreased expression of TRIB2 mRNA

NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370

G

tribbles pseudokinase 3

increases expression

Diquat results in increased expression of TRIB3 mRNA

NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497

G

TLR4 interactor with leucine-rich repeats

decreases expression

Diquat results in decreased expression of TRIL mRNA

NCBI chr 4:82,922,327...82,927,172
Ensembl chr 4:82,922,328...82,927,172

G

tripartite motif-containing 16

increases expression

Diquat results in increased expression of TRIM16 mRNA

NCBI chr10:47,485,982...47,509,010
Ensembl chr10:47,486,297...47,551,907

G

tripartite motif-containing 59

decreases expression

Diquat results in decreased expression of TRIM59 mRNA

NCBI chr 2:153,269,210...153,281,185
Ensembl chr 2:153,268,584...153,281,031

G

tripartite motif-containing 67

increases expression

Diquat results in increased expression of TRIM67 mRNA

NCBI chr19:52,763,991...52,805,906
Ensembl chr19:52,764,387...52,800,422

G

thyroid hormone receptor interactor 4

decreases expression

Diquat results in decreased expression of TRIP4 protein

NCBI chr 8:66,351,861...66,439,679
Ensembl chr 8:66,353,248...66,439,774

G

trophinin

decreases expression

Diquat results in decreased expression of TRO mRNA

NCBI chr X:19,563,395...19,574,507
Ensembl chr X:19,563,517...19,572,953

G

transcriptional repressor GATA binding 1

decreases expression

Diquat results in decreased expression of TRPS1 mRNA

NCBI chr 7:81,916,668...82,142,733
Ensembl chr 7:81,921,601...82,141,905

G

TSC22 domain family, member 1

increases expression

Diquat results in increased expression of TSC22D1 mRNA

NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958

G

tsukushi, small leucine rich proteoglycan

increases expression

Diquat results in increased expression of TSKU mRNA

NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588

G

tetraspanin 13

decreases expression

Diquat results in decreased expression of TSPAN13 mRNA

NCBI chr 6:52,738,748...52,765,503
Ensembl chr 6:52,738,758...52,765,547

G

tumor suppressing subtransferable candidate 4

decreases expression

Diquat results in decreased expression of TSSC4 protein

NCBI chr 1:198,251,986...198,254,810
Ensembl chr 1:198,235,487...198,254,980

G

thiosulfate sulfurtransferase like domain containing 3

increases expression

Diquat results in increased expression of TSTD3 protein

NCBI chr 5:35,294,652...35,304,093
Ensembl chr 5:35,294,645...35,304,101

G

tubulin, alpha 1C

increases expression

Diquat results in increased expression of TUBA1C mRNA

NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr X:130,192,016...130,199,647

G

tubulin, beta 1 class VI

decreases expression

Diquat results in decreased expression of TUBB1 protein

NCBI chr 3:163,247,990...163,257,460
Ensembl chr 3:163,247,967...163,256,063

G

tubulin, beta 2A class IIa

increases expression

Diquat results in increased expression of TUBB2A mRNA

NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714

G

TXK tyrosine kinase

decreases expression

Diquat results in decreased expression of TXK mRNA

NCBI chr14:35,463,369...35,519,448
Ensembl chr14:35,463,944...35,519,448

G

thioredoxin 2

increases expression
multiple interactions
decreases response to substance

Diquat results in increased expression of TXN2 mRNA; Diquat results in increased expression of TXN2 protein
TXN2 protein affects the reaction [Diquat results in increased cleavage of and results in increased activity of CASP3 protein]; TXN2 protein affects the reaction [Diquat results in increased cleavage of and results in increased activity of CASP9 protein]
TXN2 protein results in decreased susceptibility to Diquat

PMID:16962985 PMID:18164269 PMID:36851058

NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359

G

thioredoxin reductase 1

increases expression

Diquat results in increased expression of TXNRD1 mRNA

PMID:20826540 PMID:21172416 PMID:36851058

NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863

G

transmembrane immune signaling adaptor Tyrobp

decreases expression

Diquat results in decreased expression of TYROBP mRNA

NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848

G

tRNA-yW synthesizing protein 3 homolog

decreases expression

Diquat results in decreased expression of TYW3 mRNA

NCBI chr 2:243,529,912...243,552,043
Ensembl chr 2:243,529,946...243,552,039

G

ubiquitin A-52 residue ribosomal protein fusion product 1

increases expression

Diquat results in increased expression of UBA52 protein

NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807

G

ubiquitin-like modifier activating enzyme 7

decreases expression

Diquat results in decreased expression of UBA7 mRNA

NCBI chr 8:108,665,289...108,674,097
Ensembl chr 8:108,665,292...108,674,099

G

UbiA prenyltransferase domain containing 1

decreases expression

Diquat results in decreased expression of UBIAD1 mRNA; Diquat results in decreased expression of UBIAD1 protein

NCBI chr 5:158,856,582...158,880,490
Ensembl chr 5:158,868,672...158,880,271

G

uridine-cytidine kinase 2

decreases expression

Diquat results in decreased expression of UCK2 protein

NCBI chr13:79,380,807...79,438,121
Ensembl chr13:79,383,846...79,438,352

G

uncoupling protein 2

increases expression

Diquat results in increased expression of UCP2 mRNA

NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611

G

UDP-glucose 6-dehydrogenase

increases expression

Diquat results in increased expression of UGDH mRNA

NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354

G

UDP glucuronosyltransferase family 1 member A1

increases expression

Diquat results in increased expression of UGT1A1 mRNA

NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase 1 family, polypeptide A2

increases expression

Diquat results in increased expression of UGT1A2 mRNA

NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 1 member A9

increases expression

Diquat results in increased expression of UGT1A9 mRNA

NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase 2 family, polypeptide B1

decreases expression

Diquat results in decreased expression of UGT2B17 protein

NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986

G

UDP glycosyltransferase 8

decreases expression

Diquat results in decreased expression of UGT8A mRNA

NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660

G

ubiquitin interaction motif containing 1

decreases expression

Diquat results in decreased expression of UIMC1 protein

NCBI chr17:9,523,793...9,592,810
Ensembl chr17:9,527,794...9,592,799

G

unc-13 homolog B

increases expression

Diquat results in increased expression of UNC13B protein

NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926

G

unk like zinc finger

decreases expression

Diquat results in decreased expression of UNKL protein

NCBI chr10:14,206,125...14,252,226
Ensembl chr10:14,206,189...14,252,225

G

uridine phosphorylase 1

increases expression

Diquat results in increased expression of UPP1 mRNA

NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462

G

urocanate hydratase 1

increases expression

Diquat results in increased expression of UROC1 mRNA

NCBI chr 4:122,844,933...122,876,584
Ensembl chr 4:122,844,926...122,876,591

G

UTP18 small subunit processome component

decreases expression

Diquat results in decreased expression of UTP18 protein

NCBI chr10:78,811,879...78,839,338
Ensembl chr10:78,811,880...78,839,627

G

VANGL planar cell polarity protein 1

decreases expression

Diquat results in decreased expression of VANGL1 protein

NCBI chr 2:189,586,681...189,637,609
Ensembl chr 2:189,589,229...189,637,619

G

vesicle amine transport 1

increases expression

Diquat results in increased expression of VAT1 mRNA

NCBI chr10:86,389,549...86,397,167
Ensembl chr10:86,389,545...86,397,224

G

versican

decreases expression

Diquat results in decreased expression of VCAN mRNA

NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637

G

voltage-dependent anion channel 2

increases expression

Diquat results in increased expression of VDAC2 protein

NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553

G

ventricular zone expressed PH domain-containing 1

decreases expression

Diquat results in decreased expression of VEPH1 protein

NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266

G

VGF nerve growth factor inducible

increases expression

Diquat results in increased expression of VGF mRNA

NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341

G

vanin 1

increases expression

Diquat results in increased expression of VNN1 mRNA

NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395

G

VPS8 subunit of CORVET complex

decreases expression

Diquat results in decreased expression of VPS8 mRNA

NCBI chr11:79,402,236...79,634,234
Ensembl chr11:79,402,239...79,634,133

G

von Willebrand factor A domain containing 1

decreases expression

Diquat results in decreased expression of VWA1 mRNA; Diquat results in decreased expression of VWA1 protein

NCBI chr 5:166,377,451...166,382,784
Ensembl chr 5:166,377,455...166,382,637

G

von Willebrand factor A domain containing 3A

increases expression

Diquat results in increased expression of VWA3A mRNA

NCBI chr 1:175,293,782...175,355,588
Ensembl chr 1:175,293,873...175,355,602

G

WDFY family member 4

decreases expression

Diquat results in decreased expression of WDFY4 mRNA

NCBI chr16:8,221,853...8,450,494
Ensembl chr16:8,221,719...8,450,491

G

WD repeat domain 20

decreases expression

Diquat results in decreased expression of WDR20 protein

NCBI chr 6:129,751,952...129,821,464
Ensembl chr 6:129,752,014...129,847,339

G

WAP four-disulfide core domain 17

decreases expression

Diquat results in decreased expression of WFDC17 mRNA

NCBI chr10:68,561,954...68,562,801
Ensembl chr10:68,561,954...68,562,801

G

WAP four-disulfide core domain 2

increases expression

Diquat results in increased expression of WFDC2 mRNA

NCBI chr 3:153,286,946...153,314,832
Ensembl chr 3:153,286,131...153,292,807

G

WD repeat and SOCS box-containing 1

increases expression

Diquat results in increased expression of WSB1 mRNA

NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019

G

WW and C2 domain containing 1

increases expression

Diquat results in increased expression of WWC1 mRNA

NCBI chr10:20,300,735...20,454,393
Ensembl chr10:20,300,833...20,454,497

G

XIAP associated factor 1

decreases expression

Diquat results in decreased expression of XAF1 mRNA

NCBI chr10:56,917,378...56,929,791
Ensembl chr10:56,917,121...56,929,770

G

xanthine dehydrogenase

increases expression

Diquat results in increased expression of XDH mRNA

NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268

G

YjeF N-terminal domain containing 3

increases expression

Diquat results in increased expression of YJEFN3 mRNA

NCBI chr16:19,533,742...19,539,759
Ensembl chr16:19,533,788...19,539,728

G

Z-DNA binding protein 1

decreases expression

Diquat results in decreased expression of ZBP1 mRNA

NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870

G

zinc finger and BTB domain containing 16

increases expression

Diquat results in increased expression of ZBTB16 mRNA

NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011

G

zinc finger AN1-type containing 2A

increases expression

Diquat results in increased expression of ZFAND2A mRNA

NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677

G

zinc finger protein 239

decreases expression

Diquat results in decreased expression of ZFP239 mRNA

NCBI chr 4:151,029,431...151,039,283
Ensembl chr 4:151,029,405...151,039,529

G

zinc finger protein 830

decreases expression

Diquat results in decreased expression of ZNF830 protein

NCBI chr10:67,701,340...67,702,804
Ensembl chr10:67,701,073...67,704,523

G

zinc finger CCCH-type and G-patch domain containing

decreases expression

Diquat results in decreased expression of ZGPAT protein

NCBI chr 3:168,473,836...168,490,380
Ensembl chr 3:168,473,981...168,490,380

G

Zn regulated GTPase metalloprotein activator 1A

decreases expression

Diquat results in decreased expression of CBWD1 protein

NCBI chr 1:222,568,278...222,612,937
Ensembl chr 1:222,564,545...222,610,629

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19898
role	19868
application	19714
pesticide	18084
herbicide	16020
diquat	1182
Path 2
Term	Annotations
CHEBI ontology	19898
subatomic particle	19896
composite particle	19896
hadron	19896
baryon	19896
nucleon	19896
atomic nucleus	19896
atom	19896
main group element atom	19835
p-block element atom	19835
carbon group element atom	19774
carbon atom	19771
organic molecular entity	19771
organic molecule	19724
organic cyclic compound	19515
organic heterocyclic compound	18890
organonitrogen heterocyclic compound	18172
bipyridines	4319
bipyridine	4300
2,2'-bipyridine	1188
diquat	1182

paths to the root