Scai (suppressor of cancer cell invasion) - Rat Genome Database
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Gene: Scai (suppressor of cancer cell invasion) Rattus norvegicus
Analyze
Symbol: Scai
Name: suppressor of cancer cell invasion
RGD ID: 1594720
Description: Predicted to have transcription corepressor activity. Predicted to be involved in negative regulation of Rho protein signal transduction and negative regulation of cell migration. Predicted to localize to cytoplasm; nuclear membrane; and nucleoplasm. Orthologous to human SCAI (suppressor of cancer cell invasion); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC690538; rCG37693-like; similar to Protein C9orf126 homolog; suppressor of cancer cell invasion variant 1; suppressor of cancer cell invasion variant 2; suppressor of cancer cell invasion variant 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0323,357,586 - 23,474,218 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl323,362,707 - 23,474,170 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0328,582,235 - 28,696,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4318,856,362 - 18,960,182 (-)NCBIRGSC3.4rn4RGSC3.4
Celera321,249,476 - 21,357,620 (-)NCBICelera
Cytogenetic Map3q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
nuclear membrane  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO)

Molecular Function

References

Additional References at PubMed
PMID:19350017   PMID:23178076   PMID:32736682  


Genomics

Comparative Map Data
Scai
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0323,357,586 - 23,474,218 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl323,362,707 - 23,474,170 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0328,582,235 - 28,696,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4318,856,362 - 18,960,182 (-)NCBIRGSC3.4rn4RGSC3.4
Celera321,249,476 - 21,357,620 (-)NCBICelera
Cytogenetic Map3q12NCBI
SCAI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl9124,942,608 - 125,143,506 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl9124,942,608 - 125,143,528 (-)EnsemblGRCh38hg38GRCh38
GRCh389124,942,608 - 125,143,528 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379127,704,887 - 127,905,838 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369126,754,888 - 126,945,596 (-)NCBINCBI36hg18NCBI36
Build 349124,794,620 - 124,985,329NCBI
Celera998,352,855 - 98,553,772 (-)NCBI
Cytogenetic Map9q33.3NCBI
HuRef997,317,193 - 97,517,971 (-)NCBIHuRef
CHM1_19127,853,646 - 128,054,558 (-)NCBICHM1_1
Scai
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39238,956,226 - 39,080,770 (-)NCBIGRCm39mm39
GRCm38239,066,214 - 39,190,758 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl239,066,214 - 39,190,734 (-)EnsemblGRCm38mm10GRCm38
MGSCv37238,921,734 - 39,046,250 (-)NCBIGRCm37mm9NCBIm37
MGSCv36238,888,223 - 39,012,739 (-)NCBImm8
Celera240,791,951 - 40,916,923 (-)NCBICelera
Cytogenetic Map2BNCBI
Scai
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554193,137,749 - 3,296,454 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554193,137,745 - 3,296,460 (+)NCBIChiLan1.0ChiLan1.0
SCAI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19124,579,449 - 124,780,072 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9124,589,616 - 124,780,072 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0996,063,149 - 96,264,502 (-)NCBIMhudiblu_PPA_v0panPan3
SCAI
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl957,924,530 - 58,082,053 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1957,924,995 - 58,090,837 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Scai
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493648713,145,445 - 13,276,539 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCAI
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1265,710,770 - 265,867,067 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11265,710,644 - 265,867,099 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21299,541,771 - 299,618,963 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCAI
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11213,010,370 - 13,194,231 (+)NCBI
ChlSab1.1 Ensembl1213,010,479 - 13,192,912 (+)Ensembl
Scai
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476010,076,870 - 10,248,480 (+)NCBI

Position Markers
D3Rat276  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0323,398,877 - 23,399,020NCBIRnor6.0
Rnor_5.0328,620,703 - 28,620,846UniSTSRnor5.0
RGSC_v3.4318,892,647 - 18,892,790RGDRGSC3.4
RGSC_v3.4318,892,648 - 18,892,791UniSTSRGSC3.4
RGSC_v3.1318,789,019 - 18,789,162RGD
Celera321,290,812 - 21,290,955UniSTS
Cytogenetic Map3q11UniSTS
SHRSP x BN Map38.6699UniSTS
SHRSP x BN Map38.6699RGD
MARC_10305-10306:998934185:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0323,387,081 - 23,388,061NCBIRnor6.0
Rnor_5.0328,608,907 - 28,609,887UniSTSRnor5.0
RGSC_v3.4318,880,852 - 18,881,832UniSTSRGSC3.4
Celera321,279,016 - 21,279,996UniSTS
Cytogenetic Map3q11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3125786001Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3128136884Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3128500807Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3128500807Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3128500807Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3128500807Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3132972944Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3137891710Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3139773425Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3195176874Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3263142133477544Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3263142148562146Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3328592928136884Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3328592928136884Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)3565463925105730Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3600074834394365Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3600074834394365Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3600074834394365Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)3600074851687917Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)3600074851687917Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)3600086634394121Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)3600086634394121Rat
1558657Cm43Cardiac mass QTL 436.60.0000000293heart mass (VT:0007028)heart wet weight (CMO:0000069)3600086634394121Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31009408193415837Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31011931879772001Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)310639528127023997Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)310639528127023997Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31312691436600143Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)31312691436600143Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)heart rate (CMO:0000002)31312691436600143Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)31312691436600143Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31312691436600143Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)31312691436600143Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)heart rate (CMO:0000002)31312691436600143Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)31312691436600143Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31312691441510346Rat
2325840Bp345Blood pressure QTL 3450.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31409041129084626Rat
731172Bp151Blood pressure QTL 1510.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31409041148562146Rat
12879849Bw180Body weight QTL 1800.037body mass (VT:0001259)body weight (CMO:0000012)31409041148562146Rat
12879850Cm91Cardiac mass QTL 910.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)31409041148562146Rat
12879851Cm92Cardiac mass QTL 920.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)31409041148562146Rat
12879852Cm93Cardiac mass QTL 930.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)31409041148562146Rat
12879853Am5Aortic mass QTL 50.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)31409041148562146Rat
12879854Kidm63Kidney mass QTL 630.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)31409041148562146Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31802366463023664Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32122380366223803Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32122380366223803Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:90
Count of miRNA genes:83
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000039410, ENSRNOT00000074848
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 16 5 16 5 1 1 68 28 28 8 1
Low 2 39 41 36 3 36 7 9 6 6 13 3 7
Below cutoff 1 1 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_001074743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003753719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AABR07051828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07051829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07051830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01021248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01021249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01021250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB751604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB751605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB751606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000039410   ⟹   ENSRNOP00000030689
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl323,362,707 - 23,474,170 (-)Ensembl
RefSeq Acc Id: XM_001074743   ⟹   XP_001074743
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0323,357,586 - 23,474,218 (-)NCBI
Rnor_5.0328,582,235 - 28,696,058 (-)NCBI
RGSC_v3.4318,856,362 - 18,960,182 (-)RGD
Sequence:
RefSeq Acc Id: XM_003753719   ⟹   XP_003753767
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera321,249,476 - 21,357,620 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761809   ⟹   XP_008760031
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0323,357,586 - 23,474,210 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761810   ⟹   XP_008760032
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0323,357,586 - 23,473,492 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008775371   ⟹   XP_008773593
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera321,249,476 - 21,357,611 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008775372   ⟹   XP_008773594
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera321,249,476 - 21,356,894 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592143   ⟹   XP_017447632
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0323,357,586 - 23,473,492 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592144   ⟹   XP_017447633
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0323,357,586 - 23,474,066 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017602189   ⟹   XP_017457678
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera321,249,476 - 21,356,894 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017602191   ⟹   XP_017457680
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera321,249,476 - 21,357,466 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_001074743   ⟸   XM_001074743
- Peptide Label: isoform X1
- UniProtKB: F1M3P6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003753767   ⟸   XM_003753719
- Peptide Label: isoform X1
- UniProtKB: F1M3P6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008773593   ⟸   XM_008775371
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008773594   ⟸   XM_008775372
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008760031   ⟸   XM_008761809
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008760032   ⟸   XM_008761810
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017457680   ⟸   XM_017602191
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017457678   ⟸   XM_017602189
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017447633   ⟸   XM_017592144
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017447632   ⟸   XM_017592143
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000030689   ⟸   ENSRNOT00000039410

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692063
Promoter ID:EPDNEW_R2583
Type:multiple initiation site
Name:Scai_1
Description:suppressor of cancer cell invasion
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0323,474,181 - 23,474,241EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1594720 AgrOrtholog
Ensembl Genes ENSRNOG00000025278 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000030689 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039410 ENTREZGENE, UniProtKB/TrEMBL
InterPro DUF3550 UniProtKB/TrEMBL
  UCP013022 UniProtKB/TrEMBL
KEGG Report rno:690538 UniProtKB/TrEMBL
NCBI Gene 690538 ENTREZGENE
Pfam DUF3550 UniProtKB/TrEMBL
PhenoGen Scai PhenoGen
PIRSF UCP013022 UniProtKB/TrEMBL
UniProt F1M3P6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Scai  suppressor of cancer cell invasion  LOC100364814  rCG37693-like  Data Merged 1643240 APPROVED
2010-05-05 LOC100364814  rCG37693-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-04-23 Scai  suppressor of cancer cell invasion  LOC690538  similar to Protein C9orf126 homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC690538  similar to Protein C9orf126 homolog  LOC682319  similar to Protein C9orf126 homolog  Data Merged 1643240 APPROVED
2006-11-20 LOC690538  similar to Protein C9orf126 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC682319  similar to Protein C9orf126 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL