Scai (suppressor of cancer cell invasion) - Rat Genome Database

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Gene: Scai (suppressor of cancer cell invasion) Rattus norvegicus
Analyze
Symbol: Scai
Name: suppressor of cancer cell invasion
RGD ID: 1594720
Description: Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of Rho protein signal transduction and negative regulation of cell migration. Predicted to be located in cytoplasm; nuclear membrane; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human SCAI (suppressor of cancer cell invasion); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC690538; rCG37693-like; similar to Protein C9orf126 homolog; suppressor of cancer cell invasion variant 1; suppressor of cancer cell invasion variant 2; suppressor of cancer cell invasion variant 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2322,813,283 - 22,925,364 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl322,819,574 - 22,925,363 (-)Ensembl
Rnor_6.0323,357,586 - 23,474,218 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl323,362,707 - 23,474,170 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0328,582,235 - 28,696,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4318,856,362 - 18,960,182 (-)NCBIRGSC3.4rn4RGSC3.4
Celera321,249,476 - 21,357,620 (-)NCBICelera
Cytogenetic Map3q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
nuclear membrane  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19350017   PMID:23178076   PMID:32736682  


Genomics

Comparative Map Data
Scai
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2322,813,283 - 22,925,364 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl322,819,574 - 22,925,363 (-)Ensembl
Rnor_6.0323,357,586 - 23,474,218 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl323,362,707 - 23,474,170 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0328,582,235 - 28,696,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4318,856,362 - 18,960,182 (-)NCBIRGSC3.4rn4RGSC3.4
Celera321,249,476 - 21,357,620 (-)NCBICelera
Cytogenetic Map3q12NCBI
SCAI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389124,942,608 - 125,143,528 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl9124,942,608 - 125,143,528 (-)EnsemblGRCh38hg38GRCh38
GRCh379127,704,887 - 127,905,807 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369126,754,888 - 126,945,596 (-)NCBINCBI36hg18NCBI36
Build 349124,794,620 - 124,985,329NCBI
Celera998,352,855 - 98,553,772 (-)NCBI
Cytogenetic Map9q33.3NCBI
HuRef997,317,193 - 97,517,971 (-)NCBIHuRef
CHM1_19127,853,646 - 128,054,558 (-)NCBICHM1_1
T2T-CHM13v2.09137,140,969 - 137,341,870 (-)NCBI
Scai
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39238,956,226 - 39,080,770 (-)NCBIGRCm39mm39
GRCm39 Ensembl238,956,226 - 39,080,746 (-)Ensembl
GRCm38239,066,214 - 39,190,758 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl239,066,214 - 39,190,734 (-)EnsemblGRCm38mm10GRCm38
MGSCv37238,921,734 - 39,046,250 (-)NCBIGRCm37mm9NCBIm37
MGSCv36238,888,223 - 39,012,739 (-)NCBImm8
Celera240,791,951 - 40,916,923 (-)NCBICelera
Cytogenetic Map2BNCBI
Scai
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554193,137,749 - 3,296,454 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554193,137,745 - 3,296,460 (+)NCBIChiLan1.0ChiLan1.0
SCAI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19124,579,449 - 124,780,072 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9124,589,616 - 124,780,072 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0996,063,149 - 96,264,502 (-)NCBIMhudiblu_PPA_v0panPan3
SCAI
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1957,924,995 - 58,090,837 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl957,924,530 - 58,082,053 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha957,124,828 - 57,289,680 (+)NCBI
ROS_Cfam_1.0958,845,385 - 59,011,277 (+)NCBI
ROS_Cfam_1.0 Ensembl958,845,415 - 59,003,189 (+)Ensembl
UMICH_Zoey_3.1957,604,632 - 57,770,289 (+)NCBI
UNSW_CanFamBas_1.0957,921,148 - 58,086,095 (+)NCBI
UU_Cfam_GSD_1.0958,011,467 - 58,176,812 (+)NCBI
Scai
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947193,376,918 - 193,508,070 (-)NCBI
SpeTri2.0NW_00493648713,145,445 - 13,276,539 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCAI
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1265,710,770 - 265,867,067 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11265,710,644 - 265,867,099 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21299,541,771 - 299,618,963 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCAI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11213,010,370 - 13,194,231 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1213,010,479 - 13,192,912 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660792,908,330 - 3,093,627 (-)NCBIVero_WHO_p1.0
Scai
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476010,076,998 - 10,246,535 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462476010,076,870 - 10,248,480 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D3Rat276  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2322,858,096 - 22,858,240 (+)MAPPERmRatBN7.2
Rnor_6.0323,398,877 - 23,399,020NCBIRnor6.0
Rnor_5.0328,620,703 - 28,620,846UniSTSRnor5.0
RGSC_v3.4318,892,647 - 18,892,790RGDRGSC3.4
RGSC_v3.4318,892,648 - 18,892,791UniSTSRGSC3.4
RGSC_v3.1318,789,019 - 18,789,162RGD
Celera321,290,812 - 21,290,955UniSTS
SHRSP x BN Map38.6699UniSTS
SHRSP x BN Map38.6699RGD
Cytogenetic Map3q11UniSTS
MARC_10305-10306:998934185:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2322,846,299 - 22,847,280 (+)MAPPERmRatBN7.2
Rnor_6.0323,387,081 - 23,388,061NCBIRnor6.0
Rnor_5.0328,608,907 - 28,609,887UniSTSRnor5.0
RGSC_v3.4318,880,852 - 18,881,832UniSTSRGSC3.4
Celera321,279,016 - 21,279,996UniSTS
Cytogenetic Map3q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)31077870450302886Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1558657Cm43Cardiac mass QTL 436.60.0000000293heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)heart rate (CMO:0000002)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)heart rate (CMO:0000002)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)31737470335528639Rat
2325840Bp345Blood pressure QTL 3450.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31831145428441896Rat
731172Bp151Blood pressure QTL 1510.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31831145447233430Rat
12879849Bw180Body weight QTL 1800.037body mass (VT:0001259)body weight (CMO:0000012)31831145447233430Rat
12879850Cm91Cardiac mass QTL 910.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)31831145447233430Rat
12879851Cm92Cardiac mass QTL 920.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)31831145447233430Rat
12879852Cm93Cardiac mass QTL 930.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)31831145447233430Rat
12879853Am5Aortic mass QTL 50.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)31831145447233430Rat
12879854Kidm63Kidney mass QTL 630.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)31831145447233430Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:90
Count of miRNA genes:83
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000039410, ENSRNOT00000074848
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 16 5 16 5 1 1 68 28 28 8 1
Low 2 39 41 36 3 36 7 9 6 6 13 3 7
Below cutoff 1 1 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001399633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_001074743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003753719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB751604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB751605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB751606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000039410   ⟹   ENSRNOP00000030689
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl322,821,825 - 22,925,363 (-)Ensembl
Rnor_6.0 Ensembl323,362,707 - 23,474,170 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096988   ⟹   ENSRNOP00000083863
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl322,821,825 - 22,872,894 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104956   ⟹   ENSRNOP00000076602
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl322,819,574 - 22,925,292 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000106698   ⟹   ENSRNOP00000085924
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl322,821,825 - 22,925,292 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116892   ⟹   ENSRNOP00000090036
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl322,845,695 - 22,925,292 (-)Ensembl
RefSeq Acc Id: XM_001074743   ⟹   XP_001074743
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2322,813,283 - 22,925,364 (-)NCBI
Rnor_6.0323,357,586 - 23,474,218 (-)NCBI
Rnor_5.0328,582,235 - 28,696,058 (-)NCBI
RGSC_v3.4318,856,362 - 18,960,182 (-)RGD
Sequence:
RefSeq Acc Id: XM_008761809   ⟹   XP_008760031
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2322,813,283 - 22,925,287 (-)NCBI
Rnor_6.0323,357,586 - 23,474,210 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761810   ⟹   XP_008760032
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2322,813,283 - 22,902,108 (-)NCBI
Rnor_6.0323,357,586 - 23,473,492 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592143   ⟹   XP_017447632
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2322,813,283 - 22,902,093 (-)NCBI
Rnor_6.0323,357,586 - 23,473,492 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592144   ⟹   XP_017447633
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2322,813,283 - 22,924,648 (-)NCBI
Rnor_6.0323,357,586 - 23,474,066 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_001074743   ⟸   XM_001074743
- Peptide Label: isoform X1
- UniProtKB: F1M3P6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760031   ⟸   XM_008761809
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008760032   ⟸   XM_008761810
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017447633   ⟸   XM_017592144
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017447632   ⟸   XM_017592143
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000030689   ⟸   ENSRNOT00000039410
RefSeq Acc Id: ENSRNOP00000083863   ⟸   ENSRNOT00000096988
RefSeq Acc Id: ENSRNOP00000085924   ⟸   ENSRNOT00000106698
RefSeq Acc Id: ENSRNOP00000090036   ⟸   ENSRNOT00000116892
RefSeq Acc Id: ENSRNOP00000076602   ⟸   ENSRNOT00000104956

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M3P6-F1-model_v2 AlphaFold F1M3P6 1-606 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692063
Promoter ID:EPDNEW_R2583
Type:multiple initiation site
Name:Scai_1
Description:suppressor of cancer cell invasion
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0323,474,181 - 23,474,241EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1594720 AgrOrtholog
BioCyc Gene G2FUF-49881 BioCyc
Ensembl Genes ENSRNOG00000025278 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000030689 ENTREZGENE
  ENSRNOP00000030689.6 UniProtKB/TrEMBL
  ENSRNOP00000076602.1 UniProtKB/TrEMBL
  ENSRNOP00000083863 ENTREZGENE
  ENSRNOP00000083863.1 UniProtKB/TrEMBL
  ENSRNOP00000085924 ENTREZGENE
  ENSRNOP00000085924.1 UniProtKB/TrEMBL
  ENSRNOP00000090036.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039410 ENTREZGENE
  ENSRNOT00000039410.8 UniProtKB/TrEMBL
  ENSRNOT00000096988 ENTREZGENE
  ENSRNOT00000096988.1 UniProtKB/TrEMBL
  ENSRNOT00000104956.1 UniProtKB/TrEMBL
  ENSRNOT00000106698 ENTREZGENE
  ENSRNOT00000106698.1 UniProtKB/TrEMBL
  ENSRNOT00000116892.1 UniProtKB/TrEMBL
InterPro DUF3550 UniProtKB/TrEMBL
  UCP013022 UniProtKB/TrEMBL
KEGG Report rno:690538 UniProtKB/TrEMBL
NCBI Gene 690538 ENTREZGENE
Pfam DUF3550 UniProtKB/TrEMBL
PhenoGen Scai PhenoGen
PIRSF UCP013022 UniProtKB/TrEMBL
UniProt A0A7G3W5S2_RAT UniProtKB/TrEMBL
  A0A7G3W5S3_RAT UniProtKB/TrEMBL
  A0A7G3W5S4_RAT UniProtKB/TrEMBL
  A0A8I5ZJ84_RAT UniProtKB/TrEMBL
  A0A8I6A099_RAT UniProtKB/TrEMBL
  A0A8I6ACT9_RAT UniProtKB/TrEMBL
  A0A8I6GB80_RAT UniProtKB/TrEMBL
  F1M3P6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Scai  suppressor of cancer cell invasion  LOC100364814  rCG37693-like  Data Merged 1643240 APPROVED
2010-05-05 LOC100364814  rCG37693-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-04-23 Scai  suppressor of cancer cell invasion  LOC690538  similar to Protein C9orf126 homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC690538  similar to Protein C9orf126 homolog  LOC682319  similar to Protein C9orf126 homolog  Data Merged 1643240 APPROVED
2006-11-20 LOC690538  similar to Protein C9orf126 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC682319  similar to Protein C9orf126 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL