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Gene: Ctnna2 (catenin alpha 2) Rattus norvegicus
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Symbol: Ctnna2
Name: catenin alpha 2
Description: Predicted to have actin filament binding activity and identical protein binding activity. Predicted to be involved in several processes, including modification of postsynaptic actin cytoskeleton; negative regulation of Arp2/3 complex-mediated actin nucleation; and nervous system development. Predicted to localize to several cellular components, including the extrinsic component of synaptic membrane; hippocampal mossy fiber to CA3 synapse; and parallel fiber to Purkinje cell synapse. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations. Orthologous to human CTNNA2 (catenin alpha 2); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; endometrial cancer pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: catenin (cadherin associated protein), alpha 2; catenin alpha-2; catenin, alpha 2; Catna2; LOC297357
Orthologs:
Homo sapiens (human) : CTNNA2 (catenin alpha 2)  HGNC  Alliance
Mus musculus (house mouse) : Ctnna2 (catenin (cadherin associated protein), alpha 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ctnna2 (catenin alpha 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CTNNA2 (catenin alpha 2)
Canis lupus familiaris (dog) : CTNNA2 (catenin alpha 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctnna2 (catenin alpha 2)
Sus scrofa (pig) : CTNNA2 (catenin alpha 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04107,880,611 - 109,042,724 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04172,586,790 - 173,745,983 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44110,747,551 - 111,922,482 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14111,016,614 - 112,035,932 (-)NCBI
Celera498,339,981 - 99,476,551 (-)NCBICelera
Cytogenetic Map4q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ctnna2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305060
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.