Ctnna2 (catenin alpha 2) - Rat Genome Database

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Gene: Ctnna2 (catenin alpha 2) Rattus norvegicus
Analyze
Symbol: Ctnna2
Name: catenin alpha 2
RGD ID: 1305060
Description: Predicted to enable actin filament binding activity and identical protein binding activity. Predicted to be involved in several processes, including modification of postsynaptic actin cytoskeleton; negative regulation of Arp2/3 complex-mediated actin nucleation; and nervous system development. Predicted to be located in several cellular components, including adherens junction; basolateral plasma membrane; and postsynaptic density. Predicted to be active in several cellular components, including hippocampal mossy fiber to CA3 synapse; parallel fiber to Purkinje cell synapse; and postsynaptic density, intracellular component. Predicted to be extrinsic component of postsynaptic membrane and extrinsic component of presynaptic membrane. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations. Orthologous to human CTNNA2 (catenin alpha 2); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; endometrial cancer pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; DDT.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: catenin (cadherin associated protein), alpha 2; catenin alpha-2; catenin, alpha 2; Catna2; LOC297357
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24109,293,978 - 110,443,413 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4109,293,978 - 110,443,522 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4114,699,509 - 115,849,021 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.04110,474,640 - 111,624,120 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.04109,094,817 - 110,244,312 (-)NCBIRnor_WKY
Rnor_6.04107,880,611 - 109,042,724 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4107,881,826 - 108,008,484 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04172,586,790 - 173,745,983 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44110,747,551 - 111,922,482 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14111,016,614 - 112,035,932 (-)NCBI
Celera498,339,981 - 99,476,551 (-)NCBICelera
Cytogenetic Map4q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8909549   PMID:9950951   PMID:12089526   PMID:12123610   PMID:12695331   PMID:14657280   PMID:15034585   PMID:15630473   PMID:16182284   PMID:16457793   PMID:16691566   PMID:17114649  
PMID:19129494   PMID:23417122   PMID:25468996   PMID:30013181  


Genomics

Comparative Map Data
Ctnna2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24109,293,978 - 110,443,413 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4109,293,978 - 110,443,522 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4114,699,509 - 115,849,021 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.04110,474,640 - 111,624,120 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.04109,094,817 - 110,244,312 (-)NCBIRnor_WKY
Rnor_6.04107,880,611 - 109,042,724 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4107,881,826 - 108,008,484 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04172,586,790 - 173,745,983 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44110,747,551 - 111,922,482 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14111,016,614 - 112,035,932 (-)NCBI
Celera498,339,981 - 99,476,551 (-)NCBICelera
Cytogenetic Map4q33NCBI
CTNNA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38279,185,377 - 80,648,780 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl279,185,231 - 80,648,861 (+)EnsemblGRCh38hg38GRCh38
GRCh37279,412,503 - 80,875,905 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36279,593,634 - 80,729,416 (+)NCBINCBI36Build 36hg18NCBI36
Build 34279,651,780 - 80,787,562NCBI
Celera279,568,796 - 80,704,725 (+)NCBICelera
Cytogenetic Map2p12NCBI
HuRef279,475,616 - 80,610,857 (+)NCBIHuRef
CHM1_1279,669,347 - 80,805,984 (+)NCBICHM1_1
T2T-CHM13v2.0279,185,703 - 80,649,017 (+)NCBIT2T-CHM13v2.0
Ctnna2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39676,858,620 - 77,956,798 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl676,858,620 - 77,956,682 (-)EnsemblGRCm39 Ensembl
GRCm38676,881,637 - 77,979,815 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl676,881,637 - 77,979,699 (-)EnsemblGRCm38mm10GRCm38
MGSCv37676,831,631 - 77,929,661 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36676,811,161 - 77,909,097 (-)NCBIMGSCv36mm8
Celera678,902,485 - 80,006,681 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map633.54NCBI
Ctnna2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554245,986,073 - 6,911,826 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554245,985,170 - 7,055,830 (-)NCBIChiLan1.0ChiLan1.0
CTNNA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A81,158,206 - 82,308,244 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A81,303,559 - 82,307,258 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A79,594,694 - 80,745,885 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CTNNA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11743,472,346 - 44,504,881 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1743,472,923 - 44,557,766 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1743,168,024 - 44,195,314 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01744,284,748 - 45,372,518 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11743,368,220 - 44,455,587 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01743,410,252 - 44,491,113 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01743,907,412 - 44,995,361 (-)NCBIUU_Cfam_GSD_1.0
Ctnna2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244062924,466,584 - 5,532,415 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365565,205,481 - 6,271,304 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTNNA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl363,205,084 - 63,455,471 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1363,205,073 - 64,417,990 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2366,285,690 - 66,567,714 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CTNNA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11426,579,012 - 27,729,581 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1426,578,896 - 26,836,423 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604584,556,698 - 85,727,504 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctnna2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474922,333,710 - 23,412,593 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474922,332,750 - 23,546,165 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ctnna2
6426 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:86
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000007971
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in mean arterial blood pressure (CMO:0002035)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in systolic blood pressure (CMO:0000747)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in pulse pressure (CMO:0001882)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)470808386115808386Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)484728680129854654Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4103194656148194656Rat
2317588Eae27Experimental allergic encephalomyelitis QTL 27nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4103194805112478794Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4105789505150789505Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4106649412151649412Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)4106805662151805662Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4109827074154827074Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4109827074154827074Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat

Markers in Region
D4Mit28  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24110,275,411 - 110,275,633 (+)MAPPERmRatBN7.2
Rnor_6.04108,876,717 - 108,876,936NCBIRnor6.0
Rnor_5.04173,580,126 - 173,580,345UniSTSRnor5.0
RGSC_v3.44111,754,988 - 111,755,208RGDRGSC3.4
RGSC_v3.44111,754,989 - 111,755,208UniSTSRGSC3.4
RGSC_v3.14111,999,469 - 111,999,689RGD
Celera499,317,592 - 99,317,811UniSTS
Cytogenetic Map4q33UniSTS
D4Rat97  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24109,588,035 - 109,588,254 (+)MAPPERmRatBN7.2
Rnor_6.04108,186,335 - 108,186,553NCBIRnor6.0
Rnor_5.04172,891,980 - 172,892,198UniSTSRnor5.0
RGSC_v3.44111,052,091 - 111,052,309UniSTSRGSC3.4
RGSC_v3.44111,052,067 - 111,052,383RGDRGSC3.4
RGSC_v3.14111,296,572 - 111,296,790RGD
Celera498,632,058 - 98,632,276UniSTS
RH 3.4 Map5748.99RGD
RH 3.4 Map5748.99UniSTS
RH 2.0 Map5689.7RGD
SHRSP x BN Map449.91RGD
Cytogenetic Map4q33UniSTS
D10Got117  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24110,341,308 - 110,341,478 (+)MAPPERmRatBN7.2
Rnor_6.04108,940,816 - 108,940,985NCBIRnor6.0
Rnor_5.04173,644,225 - 173,644,394UniSTSRnor5.0
RGSC_v3.44111,820,080 - 111,820,250RGDRGSC3.4
RGSC_v3.44111,820,081 - 111,820,250UniSTSRGSC3.4
RGSC_v3.14112,064,562 - 112,064,731RGD
Celera499,375,124 - 99,375,293UniSTS
RH 3.4 Map10738.5UniSTS
RH 3.4 Map10738.5RGD
RH 2.0 Map10911.9RGD
Cytogenetic Map4q33UniSTS
D4Got218  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24109,443,598 - 109,443,868 (+)MAPPERmRatBN7.2
Rnor_6.04108,041,147 - 108,041,416NCBIRnor6.0
Rnor_5.04172,747,084 - 172,747,353UniSTSRnor5.0
RGSC_v3.44110,904,250 - 110,904,519UniSTSRGSC3.4
Celera498,488,573 - 98,488,842UniSTS
Cytogenetic Map4q33UniSTS
RH130885  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24109,894,954 - 109,895,172 (+)MAPPERmRatBN7.2
Rnor_6.04108,494,886 - 108,495,103NCBIRnor6.0
Rnor_5.04173,200,945 - 173,201,162UniSTSRnor5.0
RGSC_v3.44111,365,154 - 111,365,371UniSTSRGSC3.4
Celera498,938,638 - 98,938,855UniSTS
Cytogenetic Map4q33UniSTS
RH132643  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24109,294,322 - 109,294,514 (+)MAPPERmRatBN7.2
Rnor_6.04107,880,956 - 107,881,147NCBIRnor6.0
Rnor_5.04172,587,135 - 172,587,326UniSTSRnor5.0
RGSC_v3.44110,749,211 - 110,749,402UniSTSRGSC3.4
Celera498,340,326 - 98,340,517UniSTS
RH 3.4 Map4656.73UniSTS
Cytogenetic Map4q33UniSTS
AU049796  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24110,133,169 - 110,133,447 (+)MAPPERmRatBN7.2
Rnor_6.04108,733,001 - 108,733,278NCBIRnor6.0
Rnor_5.04173,437,188 - 173,437,465UniSTSRnor5.0
RGSC_v3.44111,609,376 - 111,609,653UniSTSRGSC3.4
Celera499,175,282 - 99,175,559UniSTS
Cytogenetic Map4q33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 72 16
Low 4 14 6 2 6 2 2 2 16 25 3 2
Below cutoff 3 35 41 33 17 33 6 7 9 8 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000007971   ⟹   ENSRNOP00000007972
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4109,294,842 - 110,443,522 (-)Ensembl
Rnor_6.0 Ensembl4107,881,826 - 108,008,484 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000080999   ⟹   ENSRNOP00000070637
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4109,293,978 - 110,443,522 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085062   ⟹   ENSRNOP00000070468
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4110,055,690 - 110,443,522 (-)Ensembl
RefSeq Acc Id: NM_001106598   ⟹   NP_001100068
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24109,293,978 - 110,443,413 (-)NCBI
Rnor_6.04107,880,611 - 109,042,663 (-)NCBI
Rnor_5.04172,586,790 - 173,745,983 (-)NCBI
RGSC_v3.44110,747,551 - 111,922,482 (-)RGD
Celera498,339,981 - 99,476,551 (-)RGD
Sequence:
RefSeq Acc Id: XM_017592544   ⟹   XP_017448033
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24109,294,249 - 110,443,316 (-)NCBI
Rnor_6.04107,880,882 - 109,042,724 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592545   ⟹   XP_017448034
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24109,295,193 - 110,443,409 (-)NCBI
Rnor_6.04107,880,882 - 109,042,724 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592546   ⟹   XP_017448035
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24109,295,036 - 110,443,314 (-)NCBI
Rnor_6.04107,881,669 - 109,042,718 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001100068   ⟸   NM_001106598
- Sequence:
RefSeq Acc Id: XP_017448033   ⟸   XM_017592544
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JYF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448034   ⟸   XM_017592545
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017448035   ⟸   XM_017592546
- Peptide Label: isoform X3
- UniProtKB: D4A6H8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000007972   ⟸   ENSRNOT00000007971
RefSeq Acc Id: ENSRNOP00000070637   ⟸   ENSRNOT00000080999
RefSeq Acc Id: ENSRNOP00000070468   ⟸   ENSRNOT00000085062

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A6H8-F1-model_v2 AlphaFold D4A6H8 1-476 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305060 AgrOrtholog
BioCyc Gene G2FUF-44092 BioCyc
Ensembl Genes ENSRNOG00000006003 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000007972 ENTREZGENE
  ENSRNOP00000007972.8 UniProtKB/TrEMBL
  ENSRNOP00000070468.2 UniProtKB/TrEMBL
  ENSRNOP00000070637 ENTREZGENE
  ENSRNOP00000070637.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007971 ENTREZGENE
  ENSRNOT00000007971.8 UniProtKB/TrEMBL
  ENSRNOT00000080999 ENTREZGENE
  ENSRNOT00000080999.2 UniProtKB/TrEMBL
  ENSRNOT00000085062.2 UniProtKB/TrEMBL
InterPro Alpha-catenin/vinculin-like_sf UniProtKB/TrEMBL
  Alpha_catenin UniProtKB/TrEMBL
  CTNNA1/CTNNA3 UniProtKB/TrEMBL
  CTNNA2 UniProtKB/TrEMBL
  Vinculin/catenin UniProtKB/TrEMBL
  Vinculin_CS UniProtKB/TrEMBL
NCBI Gene 297357 ENTREZGENE
PANTHER PTHR18914:SF23 UniProtKB/TrEMBL
  PTHR18914:SF24 UniProtKB/TrEMBL
Pfam Vinculin UniProtKB/TrEMBL
PhenoGen Ctnna2 PhenoGen
PRINTS ALPHACATENIN UniProtKB/TrEMBL
PROSITE VINCULIN_1 UniProtKB/TrEMBL
Superfamily-SCOP Vinculin/catenin UniProtKB/TrEMBL
UniProt A0A0G2JY03_RAT UniProtKB/TrEMBL
  A0A0G2JYF7 ENTREZGENE, UniProtKB/TrEMBL
  D4A6H8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Ctnna2  catenin alpha 2  Ctnna2  catenin (cadherin associated protein), alpha 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ctnna2  catenin (cadherin associated protein), alpha 2   Ctnna2_predicted  catenin (cadherin associated protein), alpha 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Ctnna2_predicted  catenin (cadherin associated protein), alpha 2 (predicted)  Catna2_predicted  catenin alpha 2 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Catna2_predicted  catenin alpha 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED