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Gene: Psap (prosaposin) Rattus norvegicus
Symbol: Psap
Name: prosaposin
RGD ID: 3423
Description: Predicted to have several functions, including beta-galactosidase activity; ganglioside binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including amide transport; animal organ development; and glycosylceramide metabolic process. Predicted to localize to several cellular components, including aggresome; late endosome; and lysosome. Human ortholog(s) of this gene implicated in atypical Gaucher's disease due to saposin c deficiency and combined saposin deficiency. Orthologous to human PSAP (prosaposin); INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Prosaposin (sulfated glycoprotein sphingolipid hydrolase activator); Prosaposin (sulfated glycoprotein, sphingolipid hydrolase activator); SGP-1; SGP1A; sulfated glycoprotein 1
Homo sapiens (human) : PSAP (prosaposin)  HGNC  Alliance
Mus musculus (house mouse) : Psap (prosaposin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Psap (prosaposin)
Pan paniscus (bonobo/pygmy chimpanzee) : PSAP (prosaposin)
Canis lupus familiaris (dog) : PSAP (prosaposin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Psap (prosaposin)
Sus scrofa (pig) : PSAP (prosaposin)
Chlorocebus sabaeus (African green monkey) : PSAP (prosaposin)
Heterocephalus glaber (naked mole-rat) : Psap (prosaposin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02029,831,302 - 29,856,876 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2029,831,314 - 29,856,875 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02031,629,564 - 31,668,605 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42027,595,048 - 27,621,574 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12027,608,847 - 27,635,374 (+)NCBI
Celera2029,653,298 - 29,678,819 (+)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Psap
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3423
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.