Psap (prosaposin) - Rat Genome Database

Name: Psap
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Psap (prosaposin) Rattus norvegicus

Analyze

Symbol:

Psap

Name:

prosaposin

RGD ID:

3423

Description:

Predicted to enable several functions, including ganglioside binding activity; protein homodimerization activity; and scaffold protein binding activity. Predicted to be involved in several processes, including cellular response to reactive oxygen species; ganglioside GM1 transport to membrane; and positive regulation of MAPK cascade. Predicted to act upstream of or within with a negative effect on gene expression. Predicted to act upstream of or within several processes, including glycosylceramide metabolic process; prostate gland development; and protein transport. Predicted to be located in several cellular components, including aggresome; late endosome; and lysosome. Human ortholog(s) of this gene implicated in atypical Gaucher's disease due to saposin c deficiency; combined saposin deficiency; and late onset Parkinson's disease. Orthologous to human PSAP (prosaposin); INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Prosaposin (sulfated glycoprotein sphingolipid hydrolase activator); Prosaposin (sulfated glycoprotein, sphingolipid hydrolase activator); SGP-1; SGP1A; sulfated glycoprotein 1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PSAP (prosaposin)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Psap (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Psap (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PSAP (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PSAP (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Psap (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PSAP (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PSAP (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Psap (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Psap (prosaposin)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PSAP (prosaposin)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	psap (prosaposin)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Sap-r	Alliance	DIOPT (InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	spp-10	Alliance	DIOPT (Hieranoid\|InParanoid\|PANTHER)
Caenorhabditis elegans (roundworm):	spp-8	Alliance	DIOPT (Hieranoid\|InParanoid\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	psap	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	20	28,214,229 - 28,240,501 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	28,214,271 - 28,240,498 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	29,228,797 - 29,255,391 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	28,615,101 - 28,641,697 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	29,357,562 - 29,384,161 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	29,831,302 - 29,856,876 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	29,831,314 - 29,856,875 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	31,629,564 - 31,668,605 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	27,595,048 - 27,621,574 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	27,608,847 - 27,635,374 (+)	NCBI
Celera	20	29,653,298 - 29,678,819 (+)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atypical Gaucher's disease due to saposin C deficiency (ISO)

Atypical Krabbe Disease due to Saposin A Deficiency (ISO)

autosomal recessive nonsyndromic deafness 12 (ISO)

combined saposin deficiency (ISO,ISS)

genetic disease (ISO)

Hearing Loss (ISO)

Krabbe disease (ISO,ISS)

late onset Parkinson's disease (ISO)

metachromatic leukodystrophy (ISO,ISS)

Metachromatic Leukodystrophy due to Saposin B Deficiency (ISO)

retinitis pigmentosa-deafness syndrome (ISO)

Usher syndrome (ISO)

Usher syndrome type 1 (ISO)

Usher Syndrome Type 1B (ISO)

Usher syndrome type 1D (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trimethylbenzene (EXP)

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2,4-dinitrotoluene (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-diaminodiphenylmethane (ISO)

aflatoxin B1 (ISO)

alendronic acid (EXP)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

Aroclor 1254 (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bexarotene (EXP)

bisphenol A (EXP,ISO)

bortezomib (ISO)

cadmium dichloride (EXP)

calcidiol (EXP)

calcitriol (ISO)

carbon nanotube (ISO)

chlordecone (ISO)

chloropicrin (ISO)

cisplatin (ISO)

clofibrate (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

cyproconazole (ISO)

decabromodiphenyl ether (ISO)

dexamethasone (EXP)

diquat (ISO)

diuron (ISO)

doxorubicin (EXP,ISO)

elemental selenium (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

formaldehyde (ISO)

glycidyl methacrylate (ISO)

ivermectin (ISO)

ketamine (EXP)

lipopolysaccharide (ISO)

maneb (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

oxaliplatin (ISO)

paclitaxel (ISO)

paracetamol (EXP,ISO)

paraquat (ISO)

perfluorooctanoic acid (ISO)

phenylpropanolamine (ISO)

pirinixic acid (ISO)

piroxicam (ISO)

propiconazole (ISO)

raloxifene (EXP)

selenium atom (ISO)

senecionine (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

tamoxifen (ISO)

testosterone (EXP)

tetrachloromethane (ISO)

thapsigargin (EXP)

titanium dioxide (ISO)

Tributyltin oxide (EXP)

trichloroethene (EXP)

undecane (EXP)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vitamin E (ISO)

Yessotoxin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (IBA,IEA,ISO)

antigen processing and presentation (ISO)

cellular response to organic substance (ISO)

cellular response to reactive oxygen species (ISO)

ceramide metabolic process (ISO)

cerebellar Purkinje cell differentiation (ISO)

cochlea development (ISO)

corneocyte development (ISO)

cornified envelope assembly (ISO)

developmental growth (ISO)

epithelial cell differentiation involved in prostate gland development (IBA,ISO)

galactosylceramide catabolic process (ISO)

ganglioside GM1 transport to membrane (IEA,ISO)

gene expression (ISO)

glucosylceramide metabolic process (ISO)

glycolipid metabolic process (ISO)

glycolipid transport (NAS)

inclusion body assembly (ISO)

intracellular protein transport (ISO)

lysosomal protein catabolic process (ISO)

lysosomal transport (IEA,ISO,ISS)

membrane lipid metabolic process (ISO)

micturition (ISO)

myelination (ISO)

nervous system process (ISO)

neuromuscular process controlling balance (ISO)

NK T cell differentiation (ISO)

positive regulation of MAPK cascade (ISO)

prostate gland growth (IBA,ISO)

protein secretion (ISO)

regulation of lipid metabolic process (IBA,IEA,ISO)

regulation of MAPK cascade (ISO)

sensory perception of sound (ISO)

sphingolipid metabolic process (IEA,ISO)

walking behavior (ISO)

Cellular Component

aggresome (ISO)

cytoplasm (ISO)

extracellular region (IEA,ISO,ISS)

extracellular space (IEA,ISO)

intracellular membrane-bounded organelle (ISO)

late endosome (IEA,ISO,ISS)

lysosome (IBA,IEA,ISO,ISS)

Molecular Function

G protein-coupled receptor binding (ISO)

ganglioside GM1 binding (IEA,ISO)

ganglioside GM2 binding (IEA,ISO)

ganglioside GM3 binding (IEA,ISO)

ganglioside GP1c binding (IEA,ISO)

ganglioside GT1b binding (IEA,ISO)

identical protein binding (ISO)

lipid antigen binding (ISO)

phospholipid binding (IEA,ISO)

protease binding (IEA,ISO)

protein binding (ISO)

protein homodimerization activity (IEA,ISO)

scaffold protein binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Biosynthesis and molecular cloning of sulfated glycoprotein 1 secreted by rat Sertoli cells: sequence similarity with the 70-kilodalton precursor to sulfatide/GM1 activator.	Collard MW, etal., Biochemistry 1988 Jun 14;27(12):4557-64.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	The evolutionary history of prosaposin: two successive tandem-duplication events gave rise to the four saposin domains in vertebrates.	Hazkani-Covo E, etal., J Mol Evol 2002 Jan;54(1):30-4.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Molecular role of sulfated glycoprotein-1 (SGP-1/prosaposin) in Sertoli cells.	Morales CR, etal., Histol Histopathol 1995 Oct;10(4):1023-34.
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
13.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data

Additional References at PubMed

PMID:1454804	PMID:8601692	PMID:9678511	PMID:11105903	PMID:11371512	PMID:12810822	PMID:12813057	PMID:12867159	PMID:12965054	PMID:14651853	PMID:14674747	PMID:14684827
PMID:15111580	PMID:15132426	PMID:15345707	PMID:16502470	PMID:17156877	PMID:17167097	PMID:17353235	PMID:17763872	PMID:18022721	PMID:18462685	PMID:18480170	PMID:18706485
PMID:19056867	PMID:19471889	PMID:19732768	PMID:20498017	PMID:20551380	PMID:21684311	PMID:22326583	PMID:22431521	PMID:23376485	PMID:23420452	PMID:23533145	PMID:23690594
PMID:24006456	PMID:24414178	PMID:24871372	PMID:24872419	PMID:25002582	PMID:25461957	PMID:26370502	PMID:27068509	PMID:27356620	PMID:27559042	PMID:28541286	PMID:28835281
PMID:29514215	PMID:29656342	PMID:31215019	PMID:33259479	PMID:33914781	PMID:37208379

Genomics

Comparative Map Data

Psap
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	20	28,214,229 - 28,240,501 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	28,214,271 - 28,240,498 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	29,228,797 - 29,255,391 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	28,615,101 - 28,641,697 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	29,357,562 - 29,384,161 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	29,831,302 - 29,856,876 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	29,831,314 - 29,856,875 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	31,629,564 - 31,668,605 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	27,595,048 - 27,621,574 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	27,608,847 - 27,635,374 (+)	NCBI
Celera	20	29,653,298 - 29,678,819 (+)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

PSAP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	71,816,298 - 71,851,251 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	71,816,298 - 71,851,251 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	73,576,055 - 73,611,008 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	73,246,061 - 73,281,088 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	73,246,063 - 73,281,015	NCBI
Celera	10	66,858,625 - 66,893,657 (-)	NCBI		Celera
Cytogenetic Map	10	q22.1	NCBI
HuRef	10	67,569,822 - 67,604,837 (-)	NCBI		HuRef
CHM1_1	10	73,858,033 - 73,893,009 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	72,687,031 - 72,721,975 (-)	NCBI		T2T-CHM13v2.0

Psap
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	60,113,436 - 60,138,379 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	60,113,449 - 60,138,376 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	60,277,628 - 60,302,600 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	60,277,627 - 60,302,597 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	59,740,376 - 59,765,348 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	59,673,095 - 59,697,957 (+)	NCBI		MGSCv36	mm8
Celera	10	61,374,486 - 61,399,457 (+)	NCBI		Celera
Cytogenetic Map	10	B4	NCBI
cM Map	10	30.02	NCBI

Psap
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955437	19,667,252 - 19,683,669 (+)	NCBI	ChiLan1.0	ChiLan1.0

PSAP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	10	83,971,953 - 84,007,011 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	68,286,359 - 68,321,349 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	70,810,591 - 70,845,593 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	70,810,881 - 70,828,781 (-)	Ensembl	panpan1.1		panPan2

PSAP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	22,571,095 - 22,603,880 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	22,572,153 - 22,603,848 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	22,708,767 - 22,741,495 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	22,847,636 - 22,880,854 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	22,847,638 - 22,880,795 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	22,753,725 - 22,786,399 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	22,952,336 - 22,985,298 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	23,306,841 - 23,339,591 (-)	NCBI		UU_Cfam_GSD_1.0

Psap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	58,483,085 - 58,516,521 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936521	6,975,770 - 7,009,136 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936521	6,975,844 - 7,009,460 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PSAP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	74,734,189 - 74,887,763 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	74,734,185 - 74,820,645 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	80,625,273 - 80,660,726 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PSAP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	59,440,327 - 59,474,773 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	59,440,311 - 59,474,986 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	20,084,030 - 20,118,523 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Psap
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	5,726,681 - 5,753,575 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	5,725,697 - 5,753,575 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Psap
178 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	327
Count of miRNA genes:	201
Interacting mature miRNAs:	245
Transcripts:	ENSRNOT00000000696
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29191651	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29191651	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29191651	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29191651	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29191651	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578807	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600972	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600972	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1527842	46527842	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1530655	46530655	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	2606836	47606836	Rat
4889870	Pur30	Proteinuria QTL 30	19	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	8042410	29322208	Rat
7411652	Foco24	Food consumption QTL 24		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	11757515	54435887	Rat
9590092	Insglur9	Insulin/glucose ratio QTL 9	18.38	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	20	11757515	54435887	Rat
4889610	Pancm3	Pancreatic morphology QTL 3	3.75	0.001	pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	20	17617832	47606836	Rat
2317880	Alcrsp25	Alcohol response QTL 25	2.3		response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	17697550	54435887	Rat
2303626	Vencon10	Ventilatory control QTL 10		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	20	19190721	54435887	Rat
2303578	Gluco50	Glucose level QTL 50	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	20	25106722	54435887	Rat
2303587	Bw93	Body weight QTL 93	13		body mass (VT:0001259)	body weight (CMO:0000012)	20	25106722	54435887	Rat
2300188	Bmd68	Bone mineral density QTL 68	6.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	20	25106722	54435887	Rat
1331747	Hrtrt16	Heart rate QTL 16	3.163		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	20	25209734	54435887	Rat

Markers in Region

RH128021

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	28,240,158 - 28,240,358 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	29,856,534 - 29,856,733	NCBI	Rnor6.0
Rnor_5.0	20	31,668,263 - 31,668,462	UniSTS	Rnor5.0
RGSC_v3.4	20	27,621,565 - 27,621,764	UniSTS	RGSC3.4
Celera	20	29,678,477 - 29,678,676	UniSTS
RH 3.4 Map	2	1521.6	UniSTS
Cytogenetic Map	20	q11	UniSTS

RH138734

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	28,234,549 - 28,234,713 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	29,850,926 - 29,851,089	NCBI	Rnor6.0
Rnor_5.0	20	31,662,655 - 31,662,818	UniSTS	Rnor5.0
RGSC_v3.4	20	27,615,957 - 27,616,120	UniSTS	RGSC3.4
Celera	20	29,672,869 - 29,673,032	UniSTS
Cytogenetic Map	20	q11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High					8			1	11		5	1
Medium	3	43	57	41	11	41	8	10	63	35	36	10	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001190236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001190237	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001190238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_013013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256403	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC113876	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC061759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB717025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK365248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO403947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO558861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DY313840	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216707	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227792	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M19936	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	S81353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000000696 ⟹ ENSRNOP00000000696

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	28,214,271 - 28,240,498 (+)	Ensembl
Rnor_6.0 Ensembl	20	29,831,314 - 29,856,875 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000093802 ⟹ ENSRNOP00000086321

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	28,228,275 - 28,240,498 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000104593 ⟹ ENSRNOP00000096557

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	28,214,271 - 28,240,498 (+)	Ensembl

RefSeq Acc Id:

NM_001190236 ⟹ NP_001177165

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	20	28,214,271 - 28,240,501 (+)	NCBI
Rnor_6.0	20	29,831,314 - 29,856,876 (+)	NCBI
Rnor_5.0	20	31,629,564 - 31,668,605 (+)	NCBI
Celera	20	29,653,298 - 29,678,819 (+)	NCBI

Sequence:

show sequence

GGCGGGGTTGGGGCTAGATTTATATGCGCCTGGTCAGCTGACGATCTGCATTGCAGCCTGCGGA
GTGAAGCGGCGCCATGTATGCTCTCGCTCTCCTCGCCAGCCTTCTGGTCACCGCTCTGACCAGC
CCTGTCCAGGACCCGAAGATCTGCTCTGGGGGCTCAGCAGTAGTGTGCAGAGATGTGAAGACGG
CGGTGGACTGTAGGGCTGTGAAGCACTGCCAGCAGATGGTCTGGAGCAAGCCCACAGCAAAATC
CCTTCCTTGTGACATATGCAAAACGGTTGTCACCGAAGCTGGGAACTTGCTGAAAGATAATGCT
ACTGAGGAGGAGATCCTCCATTACCTGGAGAAGACCTGTGCGTGGATTCATGACTCCAGCCTGT
CAGCCTCTTGCAAGGAGGTGGTTGACTCTTACCTGCCTGTCATCCTGGACATGATTAAGGGGGA
GATGAGCAACCCCGGGGAAGTGTGCTCTGCGCTCAACCTCTGCCAGTCCCTTCAGGAGTACTTG
GCCGAGCAAAACCAGAGACAGCTGGAGTCCAACAAGATCCCGGAGGTGGACCTGGCCCGCGTGG
TTGCCCCCTTCATGTCCAACATCCCTCTCCTGCTGTACCCTCAGGATCGGCCTCGCAGCCAGCC
GCAGCCCAAGGCTAACGAGGACGTCTGCCAGGACTGTATGAAGTTGGTGACTGACATCCAGACT
GCTGTGAGGACCAACTCCAGCTTTGTCCAGGGCTTGGTGGACCACGTCAAGGAGGATTGTGACC
GCCTCGGGCCAGGCGTGTCTGACATATGCAAGAACTATGTTGACCAGTATTCTGAGGTCGCCGT
CCAGATGATGATGCACATGCAGGATCAGCAACCCAAGGAAATCTGTGTGATGGTTGGCTTCTGT
GATGAGGTCAAGAGAGTGCCAATGAGGACTCTGGTCCCCGCCACTGAGGCCATCAAGAATATCC
TCCCTGCCCTGGAGCTGACGGACCCCTATGAGCAGGATGTGATCCAGGCCCAAAATGTGATTTT
CTGCCAAGTTTGTCAGCTTGTGATGCGCAAGTTGTCTGAACTGATTATCAACAATGCCACTGAG
GAACTTCTAATTAAAGGTTTGAGTAAAGCCTGCTCCCTGCTCCCTGCTCCTGCTTCAACCAAGT
GCCAGGAAGTGCTGGTAACATTTGGCCCCTCTCTGTTGGACGTCCTCATGCATGAGGTGAACCC
GAACTTTCTGTGCGGTGTGATCAGCCTCTGTTCTGCCAACCCGAATTTGGTGGGGACCCTTGAA
CAACCTGCAGCAGCCATTGTATCTGCACTGCCCAAAGAGCCTGCACCGCCAAAACAGCCTGAAG
AGCCCAAGCAGTCTGCATTGCGCGCCCATGTGCCTCCTCAGAAGAACGGGGGGTTCTGTGAGGT
GTGCAAGAAGCTGGTCATCTATTTGGAACATAACCTGGAGAAAAACAGCACCAAGGAGGAGATC
CTGGCTGCACTTGAGAAGGGCTGCAGCTTCCTGCCAGACCCTTACCAGAAGCAGTGTGATGAAT
TTGTGGCTGAGTATGAGCCCTTACTGCTGGAAATCCTTGTGGAGGTGATGGATCCTTCCTTTGT
GTGCTCGAAAATTGGAGTCTGCCCTTCTGCCTATAAGCTGCTGCTGGGAACCGAGAAGTGTGTC
TGGGGCCCAGGCTACTGGTGTCAGAACATGGAGACTGCTGCCCGATGCAATGCTGTCGATCATT
GCAAACGCCATGTGTGGAACTAGCTTTCCAGCTTGCAGAAGTCGCCTACTTGTGGGTCTAGGGT
AATGAACACATAGATCTATTTGACTTAATAAGTAGGAGCCCCCTTTTGTCTTCCCCCATCTCCT
GTCCCTTACTATAGCATTTCTGTCACGTAAGAGGCGCTGACAGCCACTTCCGTGTCCCATTTCT
GCTCCAAGGATGAGGACACTTGGGCTTCAGCTCCCCGGCTGCCCTTTTCACCCACCTGCTGGAG
GGGGGTGGTGAGCCAGAGGGCAGGAGCATGTGCTGAGCCCTCTCGGTGTGTAGGGATCATGGCC
ATCTCCTAGCGTGAGGGAACTGCGCAACTTCCTGTGCTACCAAGGAGTTTAATTTGGATGCTTA
GAAGCACAGAGTGATCAGGCCTTTAGAGTGTGGGATGGCCATTGCCACAGCACAGAGACTTGAG
AAGCACCTGCTGCAGGTGGCTTGCTTGGGACGTTGCCGTCCCTGGTCAGCCTTCATTCTGCTTT
CCCGTCTTCCCGTCTGCCTTGTTGGGGATCTGTGGGGTAGGGTGGGGAGGGGGAACTTCTGAAT
GTAACTTGCCTGTGCCGTGTGACAGTCGTGGGCCTGATCTTTTGTTTGTGAGACCCGGAAATGG
GGTCTCTGCCTGGCTGTTTGGGGTCCCATACGCCTTTCGTACCCGTAGCTCTGTTGAGCTGCTT
GTTCACCTCATGGGTGTAAGAATCGTGGATCGTTCTGGTGAGGAGACAGCCAGCAGGATGGGCA
TGTGCAGTTAAATGGACCTAGATTTTGTTTTGCACTAAAGTTTCTGTGACTTAATAAAGTTCTG
TTAACCAGAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001190237 ⟹ NP_001177166

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	20	28,214,271 - 28,240,501 (+)	NCBI
Rnor_6.0	20	29,831,314 - 29,856,876 (+)	NCBI
Rnor_5.0	20	31,629,564 - 31,668,605 (+)	NCBI
Celera	20	29,653,298 - 29,678,819 (+)	NCBI

Sequence:

show sequence

GGCGGGGTTGGGGCTAGATTTATATGCGCCTGGTCAGCTGACGATCTGCATTGCAGCCTGCGGA
GTGAAGCGGCGCCATGTATGCTCTCGCTCTCCTCGCCAGCCTTCTGGTCACCGCTCTGACCAGC
CCTGTCCAGGACCCGAAGATCTGCTCTGGGGGCTCAGCAGTAGTGTGCAGAGATGTGAAGACGG
CGGTGGACTGTAGGGCTGTGAAGCACTGCCAGCAGATGGTCTGGAGCAAGCCCACAGCAAAATC
CCTTCCTTGTGACATATGCAAAACGGTTGTCACCGAAGCTGGGAACTTGCTGAAAGATAATGCT
ACTGAGGAGGAGATCCTCCATTACCTGGAGAAGACCTGTGCGTGGATTCATGACTCCAGCCTGT
CAGCCTCTTGCAAGGAGGTGGTTGACTCTTACCTGCCTGTCATCCTGGACATGATTAAGGGGGA
GATGAGCAACCCCGGGGAAGTGTGCTCTGCGCTCAACCTCTGCCAGTCCCTTCAGGAGTACTTG
GCCGAGCAAAACCAGAGACAGCTGGAGTCCAACAAGATCCCGGAGGTGGACCTGGCCCGCGTGG
TTGCCCCCTTCATGTCCAACATCCCTCTCCTGCTGTACCCTCAGGATCGGCCTCGCAGCCAGCC
GCAGCCCAAGGCTAACGAGGACGTCTGCCAGGACTGTATGAAGTTGGTGACTGACATCCAGACT
GCTGTGAGGACCAACTCCAGCTTTGTCCAGGGCTTGGTGGACCACGTCAAGGAGGATTGTGACC
GCCTCGGGCCAGGCGTGTCTGACATATGCAAGAACTATGTTGACCAGTATTCTGAGGTCGCCGT
CCAGATGATGATGCACATGCAGGATCAGCAACCCAAGGAAATCTGTGTGATGGTTGGCTTCTGT
GATGAGGTCAAGAGAGTGCCAATGAGGACTCTGGTCCCCGCCACTGAGGCCATCAAGAATATCC
TCCCTGCCCTGGAGCTGACGGACCCCTATGAGGATGTGATCCAGGCCCAAAATGTGATTTTCTG
CCAAGTTTGTCAGCTTGTGATGCGCAAGTTGTCTGAACTGATTATCAACAATGCCACTGAGGAA
CTTCTAATTAAAGGTTTGAGTAAAGCCTGCTCCCTGCTCCCTGCTCCTGCTTCAACCAAGTGCC
AGGAAGTGCTGGTAACATTTGGCCCCTCTCTGTTGGACGTCCTCATGCATGAGGTGAACCCGAA
CTTTCTGTGCGGTGTGATCAGCCTCTGTTCTGCCAACCCGAATTTGGTGGGGACCCTTGAACAA
CCTGCAGCAGCCATTGTATCTGCACTGCCCAAAGAGCCTGCACCGCCAAAACAGCCTGAAGAGC
CCAAGCAGTCTGCATTGCGCGCCCATGTGCCTCCTCAGAAGAACGGGGGGTTCTGTGAGGTGTG
CAAGAAGCTGGTCATCTATTTGGAACATAACCTGGAGAAAAACAGCACCAAGGAGGAGATCCTG
GCTGCACTTGAGAAGGGCTGCAGCTTCCTGCCAGACCCTTACCAGAAGCAGTGTGATGAATTTG
TGGCTGAGTATGAGCCCTTACTGCTGGAAATCCTTGTGGAGGTGATGGATCCTTCCTTTGTGTG
CTCGAAAATTGGAGTCTGCCCTTCTGCCTATAAGCTGCTGCTGGGAACCGAGAAGTGTGTCTGG
GGCCCAGGCTACTGGTGTCAGAACATGGAGACTGCTGCCCGATGCAATGCTGTCGATCATTGCA
AACGCCATGTGTGGAACTAGCTTTCCAGCTTGCAGAAGTCGCCTACTTGTGGGTCTAGGGTAAT
GAACACATAGATCTATTTGACTTAATAAGTAGGAGCCCCCTTTTGTCTTCCCCCATCTCCTGTC
CCTTACTATAGCATTTCTGTCACGTAAGAGGCGCTGACAGCCACTTCCGTGTCCCATTTCTGCT
CCAAGGATGAGGACACTTGGGCTTCAGCTCCCCGGCTGCCCTTTTCACCCACCTGCTGGAGGGG
GGTGGTGAGCCAGAGGGCAGGAGCATGTGCTGAGCCCTCTCGGTGTGTAGGGATCATGGCCATC
TCCTAGCGTGAGGGAACTGCGCAACTTCCTGTGCTACCAAGGAGTTTAATTTGGATGCTTAGAA
GCACAGAGTGATCAGGCCTTTAGAGTGTGGGATGGCCATTGCCACAGCACAGAGACTTGAGAAG
CACCTGCTGCAGGTGGCTTGCTTGGGACGTTGCCGTCCCTGGTCAGCCTTCATTCTGCTTTCCC
GTCTTCCCGTCTGCCTTGTTGGGGATCTGTGGGGTAGGGTGGGGAGGGGGAACTTCTGAATGTA
ACTTGCCTGTGCCGTGTGACAGTCGTGGGCCTGATCTTTTGTTTGTGAGACCCGGAAATGGGGT
CTCTGCCTGGCTGTTTGGGGTCCCATACGCCTTTCGTACCCGTAGCTCTGTTGAGCTGCTTGTT
CACCTCATGGGTGTAAGAATCGTGGATCGTTCTGGTGAGGAGACAGCCAGCAGGATGGGCATGT
GCAGTTAAATGGACCTAGATTTTGTTTTGCACTAAAGTTTCTGTGACTTAATAAAGTTCTGTTA
ACCAGAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001190238 ⟹ NP_001177167

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	20	28,214,271 - 28,240,501 (+)	NCBI
Rnor_6.0	20	29,831,314 - 29,856,876 (+)	NCBI
Rnor_5.0	20	31,629,564 - 31,668,605 (+)	NCBI
Celera	20	29,653,298 - 29,678,819 (+)	NCBI

Sequence:

show sequence

GGCGGGGTTGGGGCTAGATTTATATGCGCCTGGTCAGCTGACGATCTGCATTGCAGCCTGCGGA
GTGAAGCGGCGCCATGTATGCTCTCGCTCTCCTCGCCAGCCTTCTGGTCACCGCTCTGACCAGC
CCTGTCCAGGACCCGAAGATCTGCTCTGGGGGCTCAGCAGTAGTGTGCAGAGATGTGAAGACGG
CGGTGGACTGTAGGGCTGTGAAGCACTGCCAGCAGATGGTCTGGAGCAAGCCCACAGCAAAATC
CCTTCCTTGTGACATATGCAAAACGGTTGTCACCGAAGCTGGGAACTTGCTGAAAGATAATGCT
ACTGAGGAGGAGATCCTCCATTACCTGGAGAAGACCTGTGCGTGGATTCATGACTCCAGCCTGT
CAGCCTCTTGCAAGGAGGTGGTTGACTCTTACCTGCCTGTCATCCTGGACATGATTAAGGGGGA
GATGAGCAACCCCGGGGAAGTGTGCTCTGCGCTCAACCTCTGCCAGTCCCTTCAGGAGTACTTG
GCCGAGCAAAACCAGAGACAGCTGGAGTCCAACAAGATCCCGGAGGTGGACCTGGCCCGCGTGG
TTGCCCCCTTCATGTCCAACATCCCTCTCCTGCTGTACCCTCAGGATCGGCCTCGCAGCCAGCC
GCAGCCCAAGGCTAACGAGGACGTCTGCCAGGACTGTATGAAGTTGGTGACTGACATCCAGACT
GCTGTGAGGACCAACTCCAGCTTTGTCCAGGGCTTGGTGGACCACGTCAAGGAGGATTGTGACC
GCCTCGGGCCAGGCGTGTCTGACATATGCAAGAACTATGTTGACCAGTATTCTGAGGTCGCCGT
CCAGATGATGATGCACATGCAACCCAAGGAAATCTGTGTGATGGTTGGCTTCTGTGATGAGGTC
AAGAGAGTGCCAATGAGGACTCTGGTCCCCGCCACTGAGGCCATCAAGAATATCCTCCCTGCCC
TGGAGCTGACGGACCCCTATGAGGATGTGATCCAGGCCCAAAATGTGATTTTCTGCCAAGTTTG
TCAGCTTGTGATGCGCAAGTTGTCTGAACTGATTATCAACAATGCCACTGAGGAACTTCTAATT
AAAGGTTTGAGTAAAGCCTGCTCCCTGCTCCCTGCTCCTGCTTCAACCAAGTGCCAGGAAGTGC
TGGTAACATTTGGCCCCTCTCTGTTGGACGTCCTCATGCATGAGGTGAACCCGAACTTTCTGTG
CGGTGTGATCAGCCTCTGTTCTGCCAACCCGAATTTGGTGGGGACCCTTGAACAACCTGCAGCA
GCCATTGTATCTGCACTGCCCAAAGAGCCTGCACCGCCAAAACAGCCTGAAGAGCCCAAGCAGT
CTGCATTGCGCGCCCATGTGCCTCCTCAGAAGAACGGGGGGTTCTGTGAGGTGTGCAAGAAGCT
GGTCATCTATTTGGAACATAACCTGGAGAAAAACAGCACCAAGGAGGAGATCCTGGCTGCACTT
GAGAAGGGCTGCAGCTTCCTGCCAGACCCTTACCAGAAGCAGTGTGATGAATTTGTGGCTGAGT
ATGAGCCCTTACTGCTGGAAATCCTTGTGGAGGTGATGGATCCTTCCTTTGTGTGCTCGAAAAT
TGGAGTCTGCCCTTCTGCCTATAAGCTGCTGCTGGGAACCGAGAAGTGTGTCTGGGGCCCAGGC
TACTGGTGTCAGAACATGGAGACTGCTGCCCGATGCAATGCTGTCGATCATTGCAAACGCCATG
TGTGGAACTAGCTTTCCAGCTTGCAGAAGTCGCCTACTTGTGGGTCTAGGGTAATGAACACATA
GATCTATTTGACTTAATAAGTAGGAGCCCCCTTTTGTCTTCCCCCATCTCCTGTCCCTTACTAT
AGCATTTCTGTCACGTAAGAGGCGCTGACAGCCACTTCCGTGTCCCATTTCTGCTCCAAGGATG
AGGACACTTGGGCTTCAGCTCCCCGGCTGCCCTTTTCACCCACCTGCTGGAGGGGGGTGGTGAG
CCAGAGGGCAGGAGCATGTGCTGAGCCCTCTCGGTGTGTAGGGATCATGGCCATCTCCTAGCGT
GAGGGAACTGCGCAACTTCCTGTGCTACCAAGGAGTTTAATTTGGATGCTTAGAAGCACAGAGT
GATCAGGCCTTTAGAGTGTGGGATGGCCATTGCCACAGCACAGAGACTTGAGAAGCACCTGCTG
CAGGTGGCTTGCTTGGGACGTTGCCGTCCCTGGTCAGCCTTCATTCTGCTTTCCCGTCTTCCCG
TCTGCCTTGTTGGGGATCTGTGGGGTAGGGTGGGGAGGGGGAACTTCTGAATGTAACTTGCCTG
TGCCGTGTGACAGTCGTGGGCCTGATCTTTTGTTTGTGAGACCCGGAAATGGGGTCTCTGCCTG
GCTGTTTGGGGTCCCATACGCCTTTCGTACCCGTAGCTCTGTTGAGCTGCTTGTTCACCTCATG
GGTGTAAGAATCGTGGATCGTTCTGGTGAGGAGACAGCCAGCAGGATGGGCATGTGCAGTTAAA
TGGACCTAGATTTTGTTTTGCACTAAAGTTTCTGTGACTTAATAAAGTTCTGTTAACCAGAAAA
AAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_013013 ⟹ NP_037145

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	20	28,214,271 - 28,240,501 (+)	NCBI
Rnor_6.0	20	29,831,314 - 29,856,876 (+)	NCBI
Rnor_5.0	20	31,629,564 - 31,668,605 (+)	NCBI
RGSC_v3.4	20	27,595,048 - 27,621,574 (+)	RGD
Celera	20	29,653,298 - 29,678,819 (+)	NCBI

Sequence:

show sequence

GGCGGGGTTGGGGCTAGATTTATATGCGCCTGGTCAGCTGACGATCTGCATTGCAGCCTGCGGA
GTGAAGCGGCGCCATGTATGCTCTCGCTCTCCTCGCCAGCCTTCTGGTCACCGCTCTGACCAGC
CCTGTCCAGGACCCGAAGATCTGCTCTGGGGGCTCAGCAGTAGTGTGCAGAGATGTGAAGACGG
CGGTGGACTGTAGGGCTGTGAAGCACTGCCAGCAGATGGTCTGGAGCAAGCCCACAGCAAAATC
CCTTCCTTGTGACATATGCAAAACGGTTGTCACCGAAGCTGGGAACTTGCTGAAAGATAATGCT
ACTGAGGAGGAGATCCTCCATTACCTGGAGAAGACCTGTGCGTGGATTCATGACTCCAGCCTGT
CAGCCTCTTGCAAGGAGGTGGTTGACTCTTACCTGCCTGTCATCCTGGACATGATTAAGGGGGA
GATGAGCAACCCCGGGGAAGTGTGCTCTGCGCTCAACCTCTGCCAGTCCCTTCAGGAGTACTTG
GCCGAGCAAAACCAGAGACAGCTGGAGTCCAACAAGATCCCGGAGGTGGACCTGGCCCGCGTGG
TTGCCCCCTTCATGTCCAACATCCCTCTCCTGCTGTACCCTCAGGATCGGCCTCGCAGCCAGCC
GCAGCCCAAGGCTAACGAGGACGTCTGCCAGGACTGTATGAAGTTGGTGACTGACATCCAGACT
GCTGTGAGGACCAACTCCAGCTTTGTCCAGGGCTTGGTGGACCACGTCAAGGAGGATTGTGACC
GCCTCGGGCCAGGCGTGTCTGACATATGCAAGAACTATGTTGACCAGTATTCTGAGGTCGCCGT
CCAGATGATGATGCACATGCAACCCAAGGAAATCTGTGTGATGGTTGGCTTCTGTGATGAGGTC
AAGAGAGTGCCAATGAGGACTCTGGTCCCCGCCACTGAGGCCATCAAGAATATCCTCCCTGCCC
TGGAGCTGACGGACCCCTATGAGCAGGATGTGATCCAGGCCCAAAATGTGATTTTCTGCCAAGT
TTGTCAGCTTGTGATGCGCAAGTTGTCTGAACTGATTATCAACAATGCCACTGAGGAACTTCTA
ATTAAAGGTTTGAGTAAAGCCTGCTCCCTGCTCCCTGCTCCTGCTTCAACCAAGTGCCAGGAAG
TGCTGGTAACATTTGGCCCCTCTCTGTTGGACGTCCTCATGCATGAGGTGAACCCGAACTTTCT
GTGCGGTGTGATCAGCCTCTGTTCTGCCAACCCGAATTTGGTGGGGACCCTTGAACAACCTGCA
GCAGCCATTGTATCTGCACTGCCCAAAGAGCCTGCACCGCCAAAACAGCCTGAAGAGCCCAAGC
AGTCTGCATTGCGCGCCCATGTGCCTCCTCAGAAGAACGGGGGGTTCTGTGAGGTGTGCAAGAA
GCTGGTCATCTATTTGGAACATAACCTGGAGAAAAACAGCACCAAGGAGGAGATCCTGGCTGCA
CTTGAGAAGGGCTGCAGCTTCCTGCCAGACCCTTACCAGAAGCAGTGTGATGAATTTGTGGCTG
AGTATGAGCCCTTACTGCTGGAAATCCTTGTGGAGGTGATGGATCCTTCCTTTGTGTGCTCGAA
AATTGGAGTCTGCCCTTCTGCCTATAAGCTGCTGCTGGGAACCGAGAAGTGTGTCTGGGGCCCA
GGCTACTGGTGTCAGAACATGGAGACTGCTGCCCGATGCAATGCTGTCGATCATTGCAAACGCC
ATGTGTGGAACTAGCTTTCCAGCTTGCAGAAGTCGCCTACTTGTGGGTCTAGGGTAATGAACAC
ATAGATCTATTTGACTTAATAAGTAGGAGCCCCCTTTTGTCTTCCCCCATCTCCTGTCCCTTAC
TATAGCATTTCTGTCACGTAAGAGGCGCTGACAGCCACTTCCGTGTCCCATTTCTGCTCCAAGG
ATGAGGACACTTGGGCTTCAGCTCCCCGGCTGCCCTTTTCACCCACCTGCTGGAGGGGGGTGGT
GAGCCAGAGGGCAGGAGCATGTGCTGAGCCCTCTCGGTGTGTAGGGATCATGGCCATCTCCTAG
CGTGAGGGAACTGCGCAACTTCCTGTGCTACCAAGGAGTTTAATTTGGATGCTTAGAAGCACAG
AGTGATCAGGCCTTTAGAGTGTGGGATGGCCATTGCCACAGCACAGAGACTTGAGAAGCACCTG
CTGCAGGTGGCTTGCTTGGGACGTTGCCGTCCCTGGTCAGCCTTCATTCTGCTTTCCCGTCTTC
CCGTCTGCCTTGTTGGGGATCTGTGGGGTAGGGTGGGGAGGGGGAACTTCTGAATGTAACTTGC
CTGTGCCGTGTGACAGTCGTGGGCCTGATCTTTTGTTTGTGAGACCCGGAAATGGGGTCTCTGC
CTGGCTGTTTGGGGTCCCATACGCCTTTCGTACCCGTAGCTCTGTTGAGCTGCTTGTTCACCTC
ATGGGTGTAAGAATCGTGGATCGTTCTGGTGAGGAGACAGCCAGCAGGATGGGCATGTGCAGTT
AAATGGACCTAGATTTTGTTTTGCACTAAAGTTTCTGTGACTTAATAAAGTTCTGTTAACCAGA
AAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006256403 ⟹ XP_006256465

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	20	28,214,229 - 28,240,501 (+)	NCBI
Rnor_6.0	20	29,831,302 - 29,856,876 (+)	NCBI
Rnor_5.0	20	31,629,564 - 31,668,605 (+)	NCBI

Sequence:

show sequence

ACTGGCGTCTGCGGCGGGGTTGGGGCTAGATTTATATGCGCCTGGTCAGCTGACGATCTGCATT
GCAGCCTGCGGAGTGAAGCGGCGCCATGTATGCTCTCGCTCTCCTCGCCAGCCTTCTGGTCACC
GCTCTGACCAGCCCTGTCCAGGACCCGAAGATCTGCTCTGGGGGCTCAGCAGTAGTGTGCAGAG
ATGTGAAGACGGCGGTGGACTGTAGGGCTGTGAAGCACTGCCAGCAGATGGTCTGGAGCAAGCC
CACAGCAAAATCCCTTCCTTGTGACATATGCAAAACGGTTGTCACCGAAGCTGGGAACTTGCTG
AAAGATAATGCTACTGAGGAGGAGATCCTCCATTACCTGGAGAAGACCTGTGCGTGGATTCATG
ACTCCAGCCTGTCAGCCTCTTGCAAGGAGGTGGTTGACTCTTACCTGCCTGTCATCCTGGACAT
GATTAAGGGGGAGATGAGCAACCCCGGGGAAGTGTGCTCTGCGCTCAACCTCTGCCAGTCCCTT
CAGGAGTACTTGGCCGAGCAAAACCAGAGACAGCTGGAGTCCAACAAGATCCCGGAGGTGGACC
TGGCCCGCGTGGTTGCCCCCTTCATGTCCAACATCCCTCTCCTGCTGTACCCTCAGGATCGGCC
TCGCAGCCAGCCGCAGCCCAAGGCTAACGAGGACGTCTGCCAGGACTGTATGAAGTTGGTGACT
GACATCCAGACTGCTGTGAGGACCAACTCCAGCTTTGTCCAGGGCTTGGTGGACCACGTCAAGG
AGGATTGTGACCGCCTCGGGCCAGGCGTGTCTGACATATGCAAGAACTATGTTGACCAGTATTC
TGAGGTCGCCGTCCAGATGATGATGCACATGGATCAGCAACCCAAGGAAATCTGTGTGATGGTT
GGCTTCTGTGATGAGGTCAAGAGAGTGCCAATGAGGACTCTGGTCCCCGCCACTGAGGCCATCA
AGAATATCCTCCCTGCCCTGGAGCTGACGGACCCCTATGAGCAGGATGTGATCCAGGCCCAAAA
TGTGATTTTCTGCCAAGTTTGTCAGCTTGTGATGCGCAAGTTGTCTGAACTGATTATCAACAAT
GCCACTGAGGAACTTCTAATTAAAGGTTTGAGTAAAGCCTGCTCCCTGCTCCCTGCTCCTGCTT
CAACCAAGTGCCAGGAAGTGCTGGTAACATTTGGCCCCTCTCTGTTGGACGTCCTCATGCATGA
GGTGAACCCGAACTTTCTGTGCGGTGTGATCAGCCTCTGTTCTGCCAACCCGAATTTGGTGGGG
ACCCTTGAACAACCTGCAGCAGCCATTGTATCTGCACTGCCCAAAGAGCCTGCACCGCCAAAAC
AGCCTGAAGAGCCCAAGCAGTCTGCATTGCGCGCCCATGTGCCTCCTCAGAAGAACGGGGGGTT
CTGTGAGGTGTGCAAGAAGCTGGTCATCTATTTGGAACATAACCTGGAGAAAAACAGCACCAAG
GAGGAGATCCTGGCTGCACTTGAGAAGGGCTGCAGCTTCCTGCCAGACCCTTACCAGAAGCAGT
GTGATGAATTTGTGGCTGAGTATGAGCCCTTACTGCTGGAAATCCTTGTGGAGGTGATGGATCC
TTCCTTTGTGTGCTCGAAAATTGGAGTCTGCCCTTCTGCCTATAAGCTGCTGCTGGGAACCGAG
AAGTGTGTCTGGGGCCCAGGCTACTGGTGTCAGAACATGGAGACTGCTGCCCGATGCAATGCTG
TCGATCATTGCAAACGCCATGTGTGGAACTAGCTTTCCAGCTTGCAGAAGTCGCCTACTTGTGG
GTCTAGGGTAATGAACACATAGATCTATTTGACTTAATAAGTAGGAGCCCCCTTTTGTCTTCCC
CCATCTCCTGTCCCTTACTATAGCATTTCTGTCACGTAAGAGGCGCTGACAGCCACTTCCGTGT
CCCATTTCTGCTCCAAGGATGAGGACACTTGGGCTTCAGCTCCCCGGCTGCCCTTTTCACCCAC
CTGCTGGAGGGGGGTGGTGAGCCAGAGGGCAGGAGCATGTGCTGAGCCCTCTCGGTGTGTAGGG
ATCATGGCCATCTCCTAGCGTGAGGGAACTGCGCAACTTCCTGTGCTACCAAGGAGTTTAATTT
GGATGCTTAGAAGCACAGAGTGATCAGGCCTTTAGAGTGTGGGATGGCCATTGCCACAGCACAG
AGACTTGAGAAGCACCTGCTGCAGGTGGCTTGCTTGGGACGTTGCCGTCCCTGGTCAGCCTTCA
TTCTGCTTTCCCGTCTTCCCGTCTGCCTTGTTGGGGATCTGTGGGGTAGGGTGGGGAGGGGGAA
CTTCTGAATGTAACTTGCCTGTGCCGTGTGACAGTCGTGGGCCTGATCTTTTGTTTGTGAGACC
CGGAAATGGGGTCTCTGCCTGGCTGTTTGGGGTCCCATACGCCTTTCGTACCCGTAGCTCTGTT
GAGCTGCTTGTTCACCTCATGGGTGTAAGAATCGTGGATCGTTCTGGTGAGGAGACAGCCAGCA
GGATGGGCATGTGCAGTTAAATGGACCTAGATTTTGTTTTGCACTAAAGTTTCTGTGACTTAAT
AAAGTTCTGTTAACCAGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001177165	(Get FASTA)	NCBI Sequence Viewer
	NP_001177166	(Get FASTA)	NCBI Sequence Viewer
	NP_001177167	(Get FASTA)	NCBI Sequence Viewer
	NP_037145	(Get FASTA)	NCBI Sequence Viewer
	XP_006256465	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA42136	(Get FASTA)	NCBI Sequence Viewer
	AAB36042	(Get FASTA)	NCBI Sequence Viewer
	AAH61759	(Get FASTA)	NCBI Sequence Viewer
	EDL93050	(Get FASTA)	NCBI Sequence Viewer
	EDL93051	(Get FASTA)	NCBI Sequence Viewer
	EDL93052	(Get FASTA)	NCBI Sequence Viewer
	EDL93053	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000000696
	ENSRNOP00000000696.5
	ENSRNOP00000086321.1
	ENSRNOP00000096557
	ENSRNOP00000096557.1
GenBank Protein	P10960	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_037145 ⟸ NM_013013
- Peptide Label:	isoform A preproprotein
- UniProtKB:	Q64190 (UniProtKB/Swiss-Prot), Q62841 (UniProtKB/Swiss-Prot), P10960 (UniProtKB/Swiss-Prot), A6K3X0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYALALLASLLVTALTSPVQDPKICSGGSAVVCRDVKTAVDCRAVKHCQQMVWSKPTAKSLPCD ICKTVVTEAGNLLKDNATEEEILHYLEKTCAWIHDSSLSASCKEVVDSYLPVILDMIKGEMSNP GEVCSALNLCQSLQEYLAEQNQRQLESNKIPEVDLARVVAPFMSNIPLLLYPQDRPRSQPQPKA NEDVCQDCMKLVTDIQTAVRTNSSFVQGLVDHVKEDCDRLGPGVSDICKNYVDQYSEVAVQMMM HMQPKEICVMVGFCDEVKRVPMRTLVPATEAIKNILPALELTDPYEQDVIQAQNVIFCQVCQLV MRKLSELIINNATEELLIKGLSKACSLLPAPASTKCQEVLVTFGPSLLDVLMHEVNPNFLCGVI SLCSANPNLVGTLEQPAAAIVSALPKEPAPPKQPEEPKQSALRAHVPPQKNGGFCEVCKKLVIY LEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDEFVAEYEPLLLEILVEVMDPSFVCSKIGVC PSAYKLLLGTEKCVWGPGYWCQNMETAARCNAVDHCKRHVWN hide sequence

RefSeq Acc Id:	NP_001177165 ⟸ NM_001190236
- Peptide Label:	isoform B preproprotein
- UniProtKB:	Q64190 (UniProtKB/Swiss-Prot), Q62841 (UniProtKB/Swiss-Prot), P10960 (UniProtKB/Swiss-Prot), A6K3W9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYALALLASLLVTALTSPVQDPKICSGGSAVVCRDVKTAVDCRAVKHCQQMVWSKPTAKSLPCD ICKTVVTEAGNLLKDNATEEEILHYLEKTCAWIHDSSLSASCKEVVDSYLPVILDMIKGEMSNP GEVCSALNLCQSLQEYLAEQNQRQLESNKIPEVDLARVVAPFMSNIPLLLYPQDRPRSQPQPKA NEDVCQDCMKLVTDIQTAVRTNSSFVQGLVDHVKEDCDRLGPGVSDICKNYVDQYSEVAVQMMM HMQDQQPKEICVMVGFCDEVKRVPMRTLVPATEAIKNILPALELTDPYEQDVIQAQNVIFCQVC QLVMRKLSELIINNATEELLIKGLSKACSLLPAPASTKCQEVLVTFGPSLLDVLMHEVNPNFLC GVISLCSANPNLVGTLEQPAAAIVSALPKEPAPPKQPEEPKQSALRAHVPPQKNGGFCEVCKKL VIYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDEFVAEYEPLLLEILVEVMDPSFVCSKI GVCPSAYKLLLGTEKCVWGPGYWCQNMETAARCNAVDHCKRHVWN hide sequence

RefSeq Acc Id:	NP_001177166 ⟸ NM_001190237
- Peptide Label:	isoform C preproprotein
- UniProtKB:	Q64190 (UniProtKB/Swiss-Prot), Q62841 (UniProtKB/Swiss-Prot), P10960 (UniProtKB/Swiss-Prot), A0A8I6ASQ4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYALALLASLLVTALTSPVQDPKICSGGSAVVCRDVKTAVDCRAVKHCQQMVWSKPTAKSLPCD ICKTVVTEAGNLLKDNATEEEILHYLEKTCAWIHDSSLSASCKEVVDSYLPVILDMIKGEMSNP GEVCSALNLCQSLQEYLAEQNQRQLESNKIPEVDLARVVAPFMSNIPLLLYPQDRPRSQPQPKA NEDVCQDCMKLVTDIQTAVRTNSSFVQGLVDHVKEDCDRLGPGVSDICKNYVDQYSEVAVQMMM HMQDQQPKEICVMVGFCDEVKRVPMRTLVPATEAIKNILPALELTDPYEDVIQAQNVIFCQVCQ LVMRKLSELIINNATEELLIKGLSKACSLLPAPASTKCQEVLVTFGPSLLDVLMHEVNPNFLCG VISLCSANPNLVGTLEQPAAAIVSALPKEPAPPKQPEEPKQSALRAHVPPQKNGGFCEVCKKLV IYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDEFVAEYEPLLLEILVEVMDPSFVCSKIG VCPSAYKLLLGTEKCVWGPGYWCQNMETAARCNAVDHCKRHVWN hide sequence

RefSeq Acc Id:	NP_001177167 ⟸ NM_001190238
- Peptide Label:	isoform D preproprotein
- UniProtKB:	Q64190 (UniProtKB/Swiss-Prot), Q62841 (UniProtKB/Swiss-Prot), P10960 (UniProtKB/Swiss-Prot), Q6P7A4 (UniProtKB/TrEMBL), F7EPE0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYALALLASLLVTALTSPVQDPKICSGGSAVVCRDVKTAVDCRAVKHCQQMVWSKPTAKSLPCD ICKTVVTEAGNLLKDNATEEEILHYLEKTCAWIHDSSLSASCKEVVDSYLPVILDMIKGEMSNP GEVCSALNLCQSLQEYLAEQNQRQLESNKIPEVDLARVVAPFMSNIPLLLYPQDRPRSQPQPKA NEDVCQDCMKLVTDIQTAVRTNSSFVQGLVDHVKEDCDRLGPGVSDICKNYVDQYSEVAVQMMM HMQPKEICVMVGFCDEVKRVPMRTLVPATEAIKNILPALELTDPYEDVIQAQNVIFCQVCQLVM RKLSELIINNATEELLIKGLSKACSLLPAPASTKCQEVLVTFGPSLLDVLMHEVNPNFLCGVIS LCSANPNLVGTLEQPAAAIVSALPKEPAPPKQPEEPKQSALRAHVPPQKNGGFCEVCKKLVIYL EHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDEFVAEYEPLLLEILVEVMDPSFVCSKIGVCP SAYKLLLGTEKCVWGPGYWCQNMETAARCNAVDHCKRHVWN hide sequence

RefSeq Acc Id:	XP_006256465 ⟸ XM_006256403
- Peptide Label:	isoform X1
- UniProtKB:	Q64190 (UniProtKB/Swiss-Prot), Q62841 (UniProtKB/Swiss-Prot), P10960 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MYALALLASLLVTALTSPVQDPKICSGGSAVVCRDVKTAVDCRAVKHCQQMVWSKPTAKSLPCD ICKTVVTEAGNLLKDNATEEEILHYLEKTCAWIHDSSLSASCKEVVDSYLPVILDMIKGEMSNP GEVCSALNLCQSLQEYLAEQNQRQLESNKIPEVDLARVVAPFMSNIPLLLYPQDRPRSQPQPKA NEDVCQDCMKLVTDIQTAVRTNSSFVQGLVDHVKEDCDRLGPGVSDICKNYVDQYSEVAVQMMM HMDQQPKEICVMVGFCDEVKRVPMRTLVPATEAIKNILPALELTDPYEQDVIQAQNVIFCQVCQ LVMRKLSELIINNATEELLIKGLSKACSLLPAPASTKCQEVLVTFGPSLLDVLMHEVNPNFLCG VISLCSANPNLVGTLEQPAAAIVSALPKEPAPPKQPEEPKQSALRAHVPPQKNGGFCEVCKKLV IYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDEFVAEYEPLLLEILVEVMDPSFVCSKIG VCPSAYKLLLGTEKCVWGPGYWCQNMETAARCNAVDHCKRHVWN hide sequence

RefSeq Acc Id:

ENSRNOP00000000696 ⟸ ENSRNOT00000000696

RefSeq Acc Id:

ENSRNOP00000086321 ⟸ ENSRNOT00000093802

RefSeq Acc Id:

ENSRNOP00000096557 ⟸ ENSRNOT00000104593

Protein Domains

Saposin A-type Saposin B-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P10960-F1-model_v2	AlphaFold	P10960	1-554	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701596

Promoter ID:

EPDNEW_R12119

Type:

initiation region

Name:

Psap_1

Description:

prosaposin

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	29,831,361 - 29,831,421	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3423	AgrOrtholog
BioCyc Gene	G2FUF-3743	BioCyc
Ensembl Genes	ENSRNOG00000000571	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000000696	ENTREZGENE
	ENSRNOT00000000696.6	UniProtKB/TrEMBL
	ENSRNOT00000093802.1	UniProtKB/TrEMBL
	ENSRNOT00000104593	ENTREZGENE
	ENSRNOT00000104593.1	UniProtKB/TrEMBL
Gene3D-CATH	Saposin-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5600088	IMAGE-MGC_LOAD
InterPro	SAP_A	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SapB_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SapB_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Saposin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Saposin-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Saposin_chordata	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SaposinB_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:25524	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:72521	IMAGE-MGC_LOAD
NCBI Gene	25524	ENTREZGENE
PANTHER	PROSAPOSIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SAPOSIN-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	SapA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SapB_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SapB_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Psap	PhenoGen
PIRSF	Saposin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	SAPOSIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	SAP_A	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SAP_B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000000571	RatGTEx
SMART	SAPA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SapB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF47862	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC228544
UniProt	A0A8I6A1Z1_RAT	UniProtKB/TrEMBL
	A0A8I6ASQ4	ENTREZGENE, UniProtKB/TrEMBL
	A6K3W9	ENTREZGENE, UniProtKB/TrEMBL
	A6K3X0	ENTREZGENE, UniProtKB/TrEMBL
	A6K3X1_RAT	UniProtKB/TrEMBL
	A6K3X2_RAT	UniProtKB/TrEMBL
	F7EPE0	ENTREZGENE
	P10960	ENTREZGENE
	Q62841	ENTREZGENE
	Q64190	ENTREZGENE
	Q6P7A4	ENTREZGENE, UniProtKB/TrEMBL
	SAP_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	F7EPE0	UniProtKB/TrEMBL
	Q62841	UniProtKB/Swiss-Prot
	Q64190	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2003-04-09	Psap	prosaposin		Prosaposin (sulfated glycoprotein, sphingolipid hydrolase activator)	Name updated	629478	APPROVED
2002-06-10	Psap	Prosaposin (sulfated glycoprotein, sphingolipid hydrolase activator)			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	secreted into the extracellular space	633775

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

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