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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
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Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
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 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Imported Annotations - CTD | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| juvenile rheumatoid arthritis | ISO | RGD:736505 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:19565504 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene-Chemical Interaction AnnotationsGene Ontology AnnotationsMolecular Pathway AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway AnnotationsReferences - curated| 1. | GOA data from the GO Consortium |
| 2. | Integration of LocusLink data, October 12, 2001 |
| 3. | KEGG |
| 4. | Machlenkin A, etal., Cancer Res. 2005 Jul 15;65(14):6435-42. |
| 5. | MGD data from the GO Consortium |
| 6. | Modzelewski B and Wasiak J, Pol Tyg Lek 1978 Aug 7;33(32):1257-8. |
| 7. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 8. | Pipeline to import KEGG annotations from KEGG into RGD |
| 9. | Plakhotin MV, etal., Veterinariia. 1978 Dec;(12):89-90. |
| 10. | Porvari KS, etal., J Biol Chem. 1994 Sep 9;269(36):22642-6. |
| 11. | RGD automated data pipeline |
| 12. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 13. | RGD automated import pipeline for gene-chemical interactions |
| 14. | Roiko K, etal., Gene 1990 May 14;89(2):223-9. |
| 15. | Saito T, etal., Urology. 2007 Oct;70(4):702-5. |
| 16. | Serrano JA, etal., J Histochem Cytochem. 1976 Oct;24(10):1046-56. |
| 17. | Virkkunen P, etal., Biochem Biophys Res Commun 1994 Jul 15;202(1):49-57. |
| 18. | Zelivianski S, etal., Nucleic Acids Res. 2004 Jul 7;32(12):3566-80. Print 2004. |
References - uncurated| PubMed | 8132635 8334986 8407898 10639192 15280042 15578709 17638863 17658863 17897319 18083097 18940592 19056867 20084276 21630459 22389722 23376485 23533145 24657436 25482440 25674224 27348306 |
Candidate Gene StatusComparative Map Data| Acp3 (Rattus norvegicus - Norway rat) |
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| ACP3 (Homo sapiens - human) |
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| Acpp (Mus musculus - house mouse) |
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| Acp3 (Chinchilla lanigera - long-tailed chinchilla) |
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| ACP3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| ACP3 (Canis lupus familiaris - dog) |
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| Acp3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| ACP3 (Sus scrofa - pig) |
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Position Markers| D8Wox15 |
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| BI283253 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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RNA-SEQ Expression| testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
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| High | ||||||||||||||||
| Medium | 2 | 5 | 3 | 2 | 2 | |||||||||||
| Low | 19 | 3 | 11 | 9 | 4 | 3 | 2 | 6 | 6 | 8 | 11 | 25 | 31 | 8 | 8 | |
| Below cutoff | 1 | 39 | 12 | 1 | 2 | 6 | 14 | 15 | 14 | 2 |
Nucleotide Sequences| RefSeq Transcripts | NM_001134901 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| NM_020072 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017595869 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017595870 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017595871 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07071383 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01056849 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01056850 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01056851 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01056852 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473954 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| DQ826426 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| M32397 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| X74969 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| X74978 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_001134901 ⟹ NP_001128373 | ||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
ATGAGAGCTGTCCCTCTGCACCTCGTCGGGACAGCAAGCCTCACCCTTGGCTTCTTGCTCCTGChide sequence |
| RefSeq Acc Id: | NM_020072 ⟹ NP_064457 | ||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
CACCTCCTACAGCTGCCACAAGCAGCTCTCTTCCCCCACCATGAGAGCTGTCCCTCTGCACCTChide sequence |
| RefSeq Acc Id: | XM_017595869 ⟹ XP_017451358 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GCAAGCCTCACCCTTGGCTTCTTGCTCCTGCTATCTCTCCGCCTGGACCCAGGCCAAGCCAAGGhide sequence |
| RefSeq Acc Id: | XM_017595870 ⟹ XP_017451359 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GACAGCAAGCCTCACCCTTGGCTTCTTGCTCCTGCTATCTCTCCGCCTGGACCCAGGCCAAGCChide sequence |
| RefSeq Acc Id: | XM_017595871 ⟹ XP_017451360 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
ACCTGCCTCTGCCTCCCAATTGCTGGGATTAAAAGCGAGCGCCACCACCCTGATATGACACATGhide sequence |
Protein Sequences| Protein RefSeqs | NP_001128373 | (Get FASTA) | NCBI Sequence Viewer |
| NP_064457 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017451358 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017451359 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017451360 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAA41806 | (Get FASTA) | NCBI Sequence Viewer |
| ABH07387 | (Get FASTA) | NCBI Sequence Viewer | |
| CAA52914 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL77357 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL77358 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL77359 | (Get FASTA) | NCBI Sequence Viewer | |
| P20646 | (Get FASTA) | NCBI Sequence Viewer |
| RefSeq Acc Id: | NP_064457 ⟸ NM_020072 |
| - Peptide Label: | short isoform precursor |
| - UniProtKB: | P20646 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MRAVPLHLVGTASLTLGFLLLLSLRLDPGQAKELKFVTLVFRHGDRGPIETFPNDPIKESSWPQhide sequence |
| RefSeq Acc Id: | NP_001128373 ⟸ NM_001134901 |
| - Peptide Label: | long isoform precursor |
| - UniProtKB: | P20646 (UniProtKB/Swiss-Prot), A0A0G2K4B4 (UniProtKB/TrEMBL) |
| - Sequence: |
MRAVPLHLVGTASLTLGFLLLLSLRLDPGQAKELKFVTLVFRHGDRGPIETFPNDPIKESSWPQhide sequence |
| RefSeq Acc Id: | XP_017451359 ⟸ XM_017595870 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MGQHYELGSYIRRRYGRFLNNSYKHDQVYIRSTDVDRTLMSAMTNLAALFPPEGISIWNPRLLWhide sequence |
| RefSeq Acc Id: | XP_017451358 ⟸ XM_017595869 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MGQHYELGSYIRRRYGRFLNNSYKHDQVYIRSTDVDRTLMSAMTNLAALFPPEGISIWNPRLLWhide sequence |
| RefSeq Acc Id: | XP_017451360 ⟸ XM_017595871 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MGQHYELGSYIRRRYGRFLNNSYKHDQVYIRSTDVDRTLMSAMTNLAALFPPEGISIWNPRLLWhide sequence |
TranscriptomePromoters| RGD ID: | 13696238 | |||||||||
| Promoter ID: | EPDNEW_R6762 | |||||||||
| Type: | multiple initiation site | |||||||||
| Name: | Acpp_1 | |||||||||
| Description: | acid phosphatase, prostate | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
| Experiment Methods: | Single-end sequencing. | |||||||||
| Position: |
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Strain Sequence Variants (Rnor 6.0)
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External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:2023 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000011820 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000016222 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOP00000072975 | ENTREZGENE, UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000016222 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOT00000085585 | ENTREZGENE, UniProtKB/TrEMBL | |
| Gene3D-CATH | 3.40.50.1240 | UniProtKB/Swiss-Prot |
| InterPro | Acid_Pase_AS | UniProtKB/Swiss-Prot |
| His_Pase_clade-2 | UniProtKB/Swiss-Prot | |
| His_PPase_superfam | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:56780 | UniProtKB/Swiss-Prot |
| NCBI Gene | 56780 | ENTREZGENE |
| Pfam | His_Phos_2 | UniProtKB/Swiss-Prot |
| PhenoGen | Acp3 | PhenoGen |
| PROSITE | HIS_ACID_PHOSPHAT_1 | UniProtKB/Swiss-Prot |
| HIS_ACID_PHOSPHAT_2 | UniProtKB/TrEMBL | |
| Superfamily-SCOP | SSF53254 | UniProtKB/Swiss-Prot |
| UniGene | Rn.40121 | ENTREZGENE |
| UniProt | A0A0G2JSL5_RAT | UniProtKB/TrEMBL |
| A0A0G2K4B4 | ENTREZGENE, UniProtKB/TrEMBL | |
| P20646 | ENTREZGENE, UniProtKB/Swiss-Prot | |
| UniProt Secondary | A6XJQ5 | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2019-09-30 | Acp3 | acid phosphatase 3 | Acpp | acid phosphatase, prostate | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2003-04-09 | Acpp | acid phosphatase, prostate | Symbol and Name updated | 629477 | APPROVED | ||
| 2003-03-06 | Acpp | acid phosphatase, prostate | Ppal | prostatic acid phosphatase (rPAP) | Data Merged | 628472 | PROVISIONAL |
| 2002-08-07 | Ppal | prostatic acid phosphatase (rPAP) | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
| 2002-06-10 | Acpp | acid phosphatase, prostate | Symbol and Name status set to approved | 70586 | APPROVED | ||
| 2001-06-12 | Acpp | acid phosphatase, prostate | Symbol and Name updated to reflect Human and Mouse nomenclature | 62408 | APPROVED | ||
| 2001-06-12 | Acpp11 | Prostatic acid phosphatase | Symbol and Name withdrawn | 62408 | WITHDRAWN |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_expression | synthesized in prostate epithelial cells, released into prostatic fluid | 69941 |
| gene_expression | synthesized in prostate epithelial cells, released into prostatic fluid | 70323 |
| gene_function | hydrolyzes phosphomonoesters under acidic condition | 69941 |
| gene_function | hydrolyzes phosphomonoesters under acidic condition | 70323 |
| gene_physical_interaction | androgen receptor binds to two conserved regions, one in the proximal promoter and another in intron 1 | 69941 |
| gene_physical_interaction | androgen receptor binds to two conserved regions, one in the proximal promoter and another in intron 1 | 70323 |
| gene_product | cDNA 1626 nt long | 69941 |
| gene_product | cDNA 1626 nt long | 70323 |
| gene_product | contains 11 exons | 69941 |
| gene_product | contains 11 exons | 70323 |
| gene_regulation | regulated by androgen | 69941 |
| gene_regulation | regulated by androgen | 70323 |
| gene_transcript | three mRNA species (4.9, 2.3 and 1.5 kb) in prostate | 69941 |
| gene_transcript | three mRNA species (4.9, 2.3 and 1.5 kb) in prostate | 70323 |
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| More on Acp3 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 2023 |
| Created: | 2000-05-25 |
| Species: | Rattus norvegicus |
| Last Modified: | 2019-11-27 |
| Status: | ACTIVE |
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.
