1-naphthyl isothiocyanate decreases expression ISO RGD:2023 6480464 1-Naphthylisothiocyanate results in decreased expression of ACPP mRNA CTD PMID:30723492 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of ACPP mRNA CTD PMID:17942748 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ACPP mRNA CTD PMID:17942748 17beta-estradiol multiple interactions ISO RGD:736505 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of ACPP mRNA more ... CTD PMID:17404688 more ... 17beta-estradiol increases expression ISO RGD:736505 6480464 Estradiol results in increased expression of ACPP mRNA CTD PMID:21795739 17beta-estradiol decreases expression ISO RGD:736505 6480464 Estradiol results in decreased expression of ACPP mRNA CTD PMID:12391264 , PMID:23019147 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:736505 6480464 Metribolone results in increased expression of ACPP protein CTD PMID:17541959 17beta-hydroxy-5alpha-androstan-3-one decreases expression ISO RGD:736505 6480464 Dihydrotestosterone results in decreased expression of ACPP mRNA CTD PMID:12391264 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of ACPP mRNA more ... CTD PMID:16214954 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ACPP mRNA CTD PMID:20702594 , PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of ACPP mRNA CTD PMID:17337447 more ... 2-hydroxypropanoic acid decreases expression ISO RGD:736505 6480464 Lactic Acid results in decreased expression of ACPP mRNA CTD PMID:30851411 3,3',4,4',5-pentachlorobiphenyl affects expression EXP 6480464 3 more ... CTD PMID:20702594 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of ACPP mRNA CTD PMID:18648102 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of ACPP mRNA CTD PMID:28973697 8-bromo-3',5'-cyclic AMP decreases expression ISO RGD:736505 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ACPP mRNA CTD PMID:22079614 aflatoxin B1 increases methylation ISO RGD:736505 6480464 Aflatoxin B1 results in increased methylation of ACPP exon CTD PMID:30157460 ammonium chloride affects expression ISO RGD:2023 6480464 Ammonium Chloride affects the expression of ACPP mRNA CTD PMID:16483693 antirheumatic drug decreases expression ISO RGD:736505 6480464 Antirheumatic Agents results in decreased expression of ACPP mRNA CTD PMID:24449571 arsane affects methylation ISO RGD:736505 6480464 Arsenic affects the methylation of ACPP gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:736505 6480464 Arsenic affects the methylation of ACPP gene CTD PMID:25304211 arsenic(3+) affects methylation ISO RGD:736505 6480464 Arsenic affects the methylation of ACPP gene CTD PMID:25304211 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of ACPP mRNA CTD PMID:19770486 benzo[a]pyrene diol epoxide I affects expression ISO RGD:736505 6480464 7 more ... CTD PMID:20382639 bicalutamide decreases expression ISO RGD:736505 6480464 bicalutamide results in decreased expression of ACPP mRNA CTD PMID:15638997 bisphenol A decreases expression ISO RGD:2023 6480464 bisphenol A results in decreased expression of ACPP mRNA, bisphenol A results in decreased expression of ACPP protein CTD PMID:12810577 , PMID:25181051 carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon results in increased expression of ACPP mRNA CTD PMID:25620056 carmustine decreases expression ISO RGD:2023 6480464 Carmustine results in decreased expression of ACPP mRNA CTD PMID:16005536 clofibric acid multiple interactions ISO RGD:2023 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ACPP mRNA CTD PMID:17602206 cobalt dichloride decreases expression ISO RGD:736505 6480464 cobaltous chloride results in decreased expression of ACPP mRNA CTD PMID:22941251 cyclosporin A increases methylation ISO RGD:736505 6480464 Cyclosporine results in increased methylation of ACPP promoter CTD PMID:27989131 decabromodiphenyl ether decreases expression ISO RGD:2023 6480464 decabromobiphenyl ether results in decreased expression of ACPP mRNA CTD PMID:23640034 diclofenac increases expression EXP 6480464 Diclofenac results in increased expression of ACPP mRNA CTD PMID:26934552 dorsomorphin multiple interactions ISO RGD:736505 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:736505 6480464 Doxorubicin results in decreased expression of ACPP mRNA CTD PMID:29803840 ellagic acid increases expression ISO RGD:736505 6480464 Ellagic Acid results in increased expression of ACPP mRNA CTD PMID:12002526 endosulfan increases expression ISO RGD:2023 6480464 Endosulfan results in increased expression of ACPP mRNA CTD PMID:29391264 finasteride multiple interactions ISO RGD:2023 6480464 Finasteride inhibits the reaction [Testosterone results in increased secretion of ACPP protein] CTD PMID:27866977 gemcitabine decreases expression ISO RGD:736505 6480464 gemcitabine results in decreased expression of ACPP protein CTD PMID:20531411 genistein decreases expression ISO RGD:736505 6480464 Genistein results in decreased expression of ACPP mRNA CTD PMID:12391264 indole-3-methanol affects expression ISO RGD:2023 6480464 indole-3-carbinol affects the expression of ACPP mRNA CTD PMID:21396975 indole-3-methanol multiple interactions ISO RGD:2023 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACPP mRNA CTD PMID:22129741 medroxyprogesterone acetate decreases expression ISO RGD:736505 6480464 Medroxyprogesterone Acetate results in decreased expression of ACPP mRNA CTD PMID:20843944 mercury dibromide multiple interactions ISO RGD:736505 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ACPP mRNA CTD PMID:27188386 methotrexate decreases expression ISO RGD:2023 6480464 Methotrexate results in decreased expression of ACPP mRNA CTD PMID:16005536 methylseleninic acid affects expression ISO RGD:736505 6480464 methylselenic acid affects the expression of ACPP mRNA CTD PMID:14617803 N-acetyl-L-cysteine multiple interactions ISO RGD:2023 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACPP mRNA CTD PMID:22129741 N-nitrosodiethylamine multiple interactions ISO RGD:2023 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ACPP mRNA, [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACPP mRNA CTD PMID:17602206 , PMID:22129741 panobinostat multiple interactions ISO RGD:736505 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ACPP mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:736505 6480464 panobinostat results in increased expression of ACPP mRNA CTD PMID:26272509 paracetamol decreases expression ISO RGD:736505 6480464 Acetaminophen results in decreased expression of ACPP mRNA CTD PMID:29067470 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:2023 6480464 perfluorooctane sulfonic acid results in decreased expression of ACPP mRNA CTD PMID:19162173 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of ACPP mRNA CTD PMID:30711707 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of ACPP mRNA CTD PMID:23091169 pirinixic acid increases expression ISO RGD:2023 6480464 pirinixic acid results in increased expression of ACPP mRNA CTD PMID:19162173 progesterone multiple interactions ISO RGD:736505 6480464 [Progesterone co-treated with Estradiol] results in decreased expression of ACPP mRNA, Progesterone inhibits the reaction [Estradiol results in increased expression of ACPP mRNA] CTD PMID:17404688 , PMID:21795739 progesterone decreases expression ISO RGD:736505 6480464 Progesterone results in decreased expression of ACPP mRNA CTD PMID:17404688 quercetin decreases expression ISO RGD:736505 6480464 Quercetin results in decreased expression of ACPP mRNA CTD PMID:12391264 rac-lactic acid decreases expression ISO RGD:736505 6480464 Lactic Acid results in decreased expression of ACPP mRNA CTD PMID:30851411 SB 431542 multiple interactions ISO RGD:736505 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Swertiamarin multiple interactions ISO RGD:2023 6480464 swertiamarin inhibits the reaction [Testosterone results in increased secretion of ACPP protein] CTD PMID:27866977 Tesaglitazar increases expression ISO RGD:2023 6480464 tesaglitazar results in increased expression of ACPP mRNA CTD PMID:21515302 testosterone multiple interactions ISO RGD:2023 6480464 Finasteride inhibits the reaction [Testosterone results in increased secretion of ACPP protein] more ... CTD PMID:27866977 testosterone increases secretion ISO RGD:2023 6480464 Testosterone results in increased secretion of ACPP protein CTD PMID:27866977 thioacetamide decreases expression ISO RGD:2023 6480464 Thioacetamide results in decreased expression of ACPP mRNA CTD PMID:23411599 tioguanine decreases expression ISO RGD:2023 6480464 Thioguanine results in decreased expression of ACPP mRNA CTD PMID:16005536 triadimefon increases expression ISO RGD:736505 6480464 triadimefon results in increased expression of ACPP mRNA CTD PMID:26705709 trichloroethene increases methylation ISO RGD:2023 6480464 Trichloroethylene results in increased methylation of ACPP gene CTD PMID:27618143 trichostatin A increases expression ISO RGD:736505 6480464 trichostatin A results in increased expression of ACPP mRNA CTD PMID:24935251 undecane decreases expression ISO RGD:2023 6480464 undecane results in decreased expression of ACPP protein CTD PMID:17337753 valproic acid affects expression ISO RGD:736505 6480464 Valproic Acid affects the expression of ACPP mRNA CTD PMID:25979313 valproic acid multiple interactions ISO RGD:736505 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ACPP mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:736505 6480464 Valproic Acid results in increased expression of ACPP mRNA CTD PMID:19101580 more ... vanadyl sulfate decreases expression ISO RGD:736505 6480464 vanadyl sulfate results in decreased expression of ACPP mRNA CTD PMID:16330358 zoledronic acid decreases expression ISO RGD:736505 6480464 zoledronic acid results in decreased expression of ACPP mRNA CTD PMID:24714768
Biological Process adenosine metabolic process ISO UniProtKB:P15309 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 adenosine metabolic process IDA 2290270 (MGI:MGI:3849266, PMID:18940592) UniProtKB MGI:MGI:3849266 , PMID:18940592 dephosphorylation ISO UniProtKB:P15309 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 dephosphorylation ISO RGD:2023 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 nucleotide metabolic process IMP 2290270 (MGI:MGI:3849266, PMID:18940592) UniProtKB MGI:MGI:3849266 , PMID:18940592 positive regulation of adenosine receptor signaling pathway ISO UniProtKB:P15309 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 protein homotetramerization ISO UniProtKB:P15309 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 purine nucleobase metabolic process IMP 2290270 (MGI:MGI:3849266, PMID:18940592) UniProtKB MGI:MGI:3849266 , PMID:18940592 regulation of sensory perception of pain ISO UniProtKB:P15309 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 regulation of sensory perception of pain IMP 2290270 (MGI:MGI:3849266, PMID:18940592) UniProtKB MGI:MGI:3849266 , PMID:18940592 thiamine metabolic process IMP 2290270 (MGI:MGI:3849266, PMID:18940592) UniProtKB MGI:MGI:3849266 , PMID:18940592 Cellular Component apical part of cell ISO RGD:2023 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 extracellular region IEA UniProtKB-KW:KW-0964 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 extracellular space ISO UniProtKB:P15309 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 filopodium IDA 2290270 (MGI:MGI:5284775, PMID:17658863) UniProtKB MGI:MGI:5284775 , PMID:17658863 Golgi cisterna ISO RGD:2023 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 integral component of membrane IDA 2290270 (MGI:MGI:5284775, PMID:17658863) UniProtKB MGI:MGI:5284775 , PMID:17658863 lysosome IEA UniProtKB-KW:KW-0458 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 membrane IEA UniProtKB-KW:KW-0472 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 multivesicular body ISO RGD:2023 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 plasma membrane IDA 2290270 (MGI:MGI:3849266 more ... UniProtKB MGI:MGI:3849266 more ... plasma membrane ISO UniProtKB:P15309 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 secretory granule ISO RGD:2023 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 vesicle membrane IDA 2290270 (MGI:MGI:3849266, PMID:18940592) UniProtKB MGI:MGI:3849266 , PMID:18940592 Molecular Function 5'-nucleotidase activity ISO UniProtKB:P15309 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 acid phosphatase activity ISS 2290270 (MGI:MGI:2152343, PMID:2373368) MGI MGI:MGI:2152343 , PMID:2373368 acid phosphatase activity ISO UniProtKB:P15309 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 acid phosphatase activity ISO RGD:2023 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 choline binding ISO RGD:2023 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 hydrolase activity IEA UniProtKB-KW:KW-0378 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 identical protein binding ISO UniProtKB:P15309 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 lysophosphatidic acid phosphatase activity ISO UniProtKB:P15309 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 phosphatase activity ISO UniProtKB:P15309 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 protein homodimerization activity ISO UniProtKB:P15309 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 protein homodimerization activity ISO RGD:2023 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 thiamine phosphate phosphatase activity IMP 2290270 (MGI:MGI:3849266, PMID:18940592) UniProtKB MGI:MGI:3849266 , PMID:18940592
Gene-Chemical Interaction Annotations
