Rab36 (RAB36, member RAS oncogene family) - Rat Genome Database

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Gene: Rab36 (RAB36, member RAS oncogene family) Rattus norvegicus
Analyze
Symbol: Rab36
Name: RAB36, member RAS oncogene family
RGD ID: 1596098
Description: Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in vesicle-mediated transport. Orthologous to human RAB36 (RAB36, member RAS oncogene family); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC690407; ras-related protein Rab-36; similar to RAB36, member RAS oncogene family
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82013,606,086 - 13,624,208 (-)NCBIGRCr8
mRatBN7.22013,606,700 - 13,624,304 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2013,608,136 - 13,624,170 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2014,314,630 - 14,330,407 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02013,675,463 - 13,691,240 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02014,148,058 - 14,163,835 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02014,557,485 - 14,573,939 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2014,557,740 - 14,573,519 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02016,740,064 - 16,755,978 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42014,111,728 - 14,127,278 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2015,091,251 - 15,107,052 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Rab36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82013,606,086 - 13,624,208 (-)NCBIGRCr8
mRatBN7.22013,606,700 - 13,624,304 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2013,608,136 - 13,624,170 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2014,314,630 - 14,330,407 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02013,675,463 - 13,691,240 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02014,148,058 - 14,163,835 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02014,557,485 - 14,573,939 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2014,557,740 - 14,573,519 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02016,740,064 - 16,755,978 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42014,111,728 - 14,127,278 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2015,091,251 - 15,107,052 (-)NCBICelera
Cytogenetic Map20p12NCBI
RAB36
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382223,145,324 - 23,169,280 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2223,145,366 - 23,165,663 (+)EnsemblGRCh38hg38GRCh38
GRCh372223,487,511 - 23,507,850 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362221,817,513 - 21,836,531 (+)NCBINCBI36Build 36hg18NCBI36
Build 342221,812,066 - 21,831,085NCBI
Celera227,302,063 - 7,321,070 (+)NCBICelera
Cytogenetic Map22q11.23NCBI
HuRef226,455,237 - 6,474,245 (+)NCBIHuRef
CHM1_12223,499,786 - 23,518,792 (+)NCBICHM1_1
T2T-CHM13v2.02223,568,177 - 23,592,144 (+)NCBIT2T-CHM13v2.0
Rab36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391074,872,727 - 74,890,580 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1074,872,890 - 74,890,580 (+)EnsemblGRCm39 Ensembl
GRCm381075,036,895 - 75,054,748 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1075,037,058 - 75,054,748 (+)EnsemblGRCm38mm10GRCm38
MGSCv371074,499,834 - 74,516,845 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361074,480,805 - 74,497,816 (+)NCBIMGSCv36mm8
Celera1076,084,913 - 76,101,889 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1038.49NCBI
Rab36
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554557,575,875 - 7,587,972 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554557,574,376 - 7,590,024 (+)NCBIChiLan1.0ChiLan1.0
RAB36
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22332,976,440 - 33,003,010 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12235,085,772 - 35,106,142 (-)NCBINHGRI_mPanPan1
PanPan1.12221,768,203 - 21,785,755 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2221,768,203 - 21,785,755 (+)Ensemblpanpan1.1panPan2
RAB36
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12627,831,256 - 27,845,918 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2627,831,196 - 27,844,670 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2626,906,969 - 26,921,643 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02629,235,182 - 29,249,889 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2629,235,189 - 29,245,936 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12627,318,531 - 27,333,235 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02626,936,027 - 26,950,729 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02627,925,302 - 27,940,012 (+)NCBIUU_Cfam_GSD_1.0
Rab36
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118142,475,251 - 142,491,662 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936619264,252 - 276,529 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936619262,356 - 278,682 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB36
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1449,188,360 - 49,204,656 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11449,186,282 - 49,202,334 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21452,612,204 - 52,625,420 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAB36
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1192,720,771 - 2,737,989 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl192,718,883 - 2,737,602 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660854,389,296 - 4,405,578 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab36
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247479,506,138 - 9,519,176 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247479,504,525 - 9,521,315 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:284
Count of miRNA genes:163
Interacting mature miRNAs:187
Transcripts:ENSRNOT00000001772
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804392029865039Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
1598870Bp289Blood pressure QTL 2892.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)20821635953216359Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
1581577Pur15Proteinuria QTL 154.380.0002urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)20804392015089182Rat
1598858Cm61Cardiac mass QTL 613.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)20821635953216359Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)201224324249189476Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat

Markers in Region
RH138065  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22013,621,350 - 13,621,523 (+)MAPPERmRatBN7.2
Rnor_6.02014,570,960 - 14,571,132NCBIRnor6.0
Rnor_5.02016,752,997 - 16,753,169UniSTSRnor5.0
RGSC_v3.42014,124,719 - 14,124,891UniSTSRGSC3.4
Celera2015,104,493 - 15,104,665UniSTS
Cytogenetic Map20p12UniSTS
AU049161  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22013,624,960 - 13,625,093 (+)MAPPERmRatBN7.2
Rnor_6.02014,574,570 - 14,574,700NCBIRnor6.0
Rnor_5.02016,756,607 - 16,756,737UniSTSRnor5.0
RGSC_v3.42014,128,329 - 14,128,459UniSTSRGSC3.4
Celera2015,108,103 - 15,108,233UniSTS
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 49 113 85 84 53 23 53 6 209 95 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000001772   ⟹   ENSRNOP00000001772
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2013,608,136 - 13,619,185 (-)Ensembl
Rnor_6.0 Ensembl2014,557,740 - 14,573,519 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095296   ⟹   ENSRNOP00000078135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2013,608,136 - 13,624,170 (-)Ensembl
RefSeq Acc Id: NM_001109589   ⟹   NP_001103059
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,606,086 - 13,623,513 (-)NCBI
mRatBN7.22013,606,700 - 13,624,128 (-)NCBI
Rnor_6.02014,557,739 - 14,573,519 (-)NCBI
Rnor_5.02016,740,064 - 16,755,978 (-)NCBI
RGSC_v3.42014,111,728 - 14,127,278 (-)RGD
Celera2015,091,251 - 15,107,052 (-)RGD
Sequence:
RefSeq Acc Id: NM_001415699   ⟹   NP_001402628
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,606,086 - 13,623,513 (-)NCBI
mRatBN7.22013,606,700 - 13,624,128 (-)NCBI
RefSeq Acc Id: XM_063279528   ⟹   XP_063135598
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,606,086 - 13,624,208 (-)NCBI
RefSeq Acc Id: XM_063279529   ⟹   XP_063135599
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,606,086 - 13,623,378 (-)NCBI
RefSeq Acc Id: XR_010060757
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82013,609,402 - 13,624,208 (-)NCBI
RefSeq Acc Id: NP_001103059   ⟸   NM_001109589
- UniProtKB: B2RZ53 (UniProtKB/TrEMBL),   F7F2S0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000001772   ⟸   ENSRNOT00000001772
Ensembl Acc Id: ENSRNOP00000078135   ⟸   ENSRNOT00000095296
RefSeq Acc Id: NP_001402628   ⟸   NM_001415699
- UniProtKB: F7F2S0 (UniProtKB/TrEMBL),   B2RZ53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135598   ⟸   XM_063279528
- Peptide Label: isoform X1
- UniProtKB: A0A8I5YC69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135599   ⟸   XM_063279529
- Peptide Label: isoform X2
- UniProtKB: F7F2S0 (UniProtKB/TrEMBL),   B2RZ53 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RZ53-F1-model_v2 AlphaFold B2RZ53 1-267 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701545
Promoter ID:EPDNEW_R12069
Type:single initiation site
Name:Rab36_1
Description:RAB36, member RAS oncogene family
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02014,573,527 - 14,573,587EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1596098 AgrOrtholog
BioCyc Gene G2FUF-4102 BioCyc
Ensembl Genes ENSRNOG00000001311 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001772.7 UniProtKB/TrEMBL
  ENSRNOT00000095296.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8368465 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Rab UniProtKB/TrEMBL
  Ras_GTPase UniProtKB/TrEMBL
  Small_GTP_bd UniProtKB/TrEMBL
KEGG Report rno:690407 UniProtKB/TrEMBL
MGC_CLONE MGC:189269 IMAGE-MGC_LOAD
NCBI Gene 690407 ENTREZGENE
PANTHER RAS-RELATED PROTEIN RAB UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-36 UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PhenoGen Rab36 PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001311 RatGTEx
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8I5YC69 ENTREZGENE, UniProtKB/TrEMBL
  B2RZ53 ENTREZGENE, UniProtKB/TrEMBL
  F7F2S0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Rab36  RAB36, member RAS oncogene family  LOC690407  similar to RAB36, member RAS oncogene family  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC690407  similar to RAB36, member RAS oncogene family      Symbol and Name status set to provisional 70820 PROVISIONAL