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Gene: Cdk7 (cyclin-dependent kinase 7) Rattus norvegicus
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Symbol: Cdk7
Name: cyclin-dependent kinase 7
Description: Exhibits cyclin-dependent protein serine/threonine kinase activity. Involved in protein phosphorylation and transcription by RNA polymerase II. Localizes to several cellular components, including the cytoskeleton; cytosol; and transcription factor TFIIH holo complex. Orthologous to human CDK7 (cyclin dependent kinase 7); PARTICIPATES IN RNA polymerase II transcription initiation pathway; RNA polymerase II transcription pathway; cell cycle pathway, mitotic; INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; dibutyl phthalate.
Type: protein-coding
RefSeq Status: MODEL
Also known as: 39 protein kinase; CAK; CDK-activating kinase; CDK-activating kinase 1; cell division protein kinase 7; cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog Xenopus laevis cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase); LOW QUALITY PROTEIN: cyclin-dependent kinase 7; P39 Mo15; TFIIH basal transcription factor complex kinase subunit
Orthologs:
Homo sapiens (human) : CDK7 (cyclin dependent kinase 7)  HGNC  Alliance
Mus musculus (house mouse) : Cdk7 (cyclin-dependent kinase 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk7 (cyclin dependent kinase 7)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK7 (cyclin dependent kinase 7)
Canis lupus familiaris (dog) : CDK7 (cyclin dependent kinase 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk7 (cyclin dependent kinase 7)
Sus scrofa (pig) : CDK7 (cyclin dependent kinase 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0230,710,642 - 30,735,522 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0249,869,631 - 49,894,108 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4231,500,629 - 31,525,590 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1231,422,411 - 31,445,843 (-)NCBI
Celera227,854,542 - 27,879,123 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cdk7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621124
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.