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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ssbp3 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | SSBP3 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SSBP3 mRNA | CTD | PMID:22079256 | Ssbp3 | Rat | 1,1-dichloroethene | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of SSBP3 mRNA | CTD | PMID:26682919 | Ssbp3 | Rat | 1,2-dimethylhydrazine | affects expression | ISO | Ssbp3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of SSBP3 mRNA | CTD | PMID:22206623 | Ssbp3 | Rat | 17beta-estradiol | increases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Estradiol results in increased expression of SSBP3 mRNA | CTD | PMID:39298647 | Ssbp3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SSBP3 mRNA | CTD | PMID:15358164 and PMID:21215274 | Ssbp3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SSBP3 mRNA | CTD | PMID:21570461 | Ssbp3 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of SSBP3 mRNA | CTD | PMID:21346803 | Ssbp3 | Rat | 2-butoxyethanol | increases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | n-butoxyethanol results in increased expression of SSBP3 mRNA | CTD | PMID:19812364 | Ssbp3 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | SSBP3 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SSBP3 mRNA | CTD | PMID:30851411 | Ssbp3 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SSBP3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of SSBP3 mRNA | CTD | PMID:28628672 | Ssbp3 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | SSBP3 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in increased methylation of SSBP3 gene and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of SSBP3 mRNA | CTD | PMID:28628672 and PMID:31601247 | Ssbp3 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | SSBP3 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of SSBP3 gene | CTD | PMID:31601247 | Ssbp3 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | bisphenol S results in increased expression of SSBP3 mRNA | CTD | PMID:39298647 | Ssbp3 | Rat | 4-hydroxynon-2-enal | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of SSBP3 mRNA | CTD | PMID:19191707 | Ssbp3 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of SSBP3 mRNA | CTD | PMID:36843608 | Ssbp3 | Rat | aflatoxin B1 | decreases expression | ISO | SSBP3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of SSBP3 mRNA | CTD | PMID:27153756 | Ssbp3 | Rat | all-trans-retinoic acid | decreases expression | ISO | SSBP3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SSBP3 mRNA | CTD | PMID:33167477 | Ssbp3 | Rat | arsenite(3-) | increases methylation | ISO | SSBP3 (Homo sapiens) | 6480464 | arsenite results in increased methylation of SSBP3 promoter | CTD | PMID:23974009 | Ssbp3 | Rat | arsenous acid | decreases expression | ISO | SSBP3 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of SSBP3 mRNA | CTD | PMID:22521957 | Ssbp3 | Rat | benzo[a]pyrene | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of SSBP3 mRNA | CTD | PMID:21569818 | Ssbp3 | Rat | benzo[a]pyrene | affects methylation | ISO | SSBP3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SSBP3 intron | CTD | PMID:30157460 | Ssbp3 | Rat | benzo[a]pyrene | decreases methylation | ISO | SSBP3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of SSBP3 5' UTR | CTD | PMID:27901495 | Ssbp3 | Rat | benzo[a]pyrene | increases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SSBP3 mRNA | CTD | PMID:22228805 | Ssbp3 | Rat | benzo[a]pyrene | decreases expression | ISO | SSBP3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of SSBP3 mRNA | CTD | PMID:20106945 more ... | Ssbp3 | Rat | benzo[e]pyrene | decreases methylation | ISO | SSBP3 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of SSBP3 intron | CTD | PMID:30157460 | Ssbp3 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of SSBP3 mRNA | CTD | PMID:34319233 | Ssbp3 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of SSBP3 mRNA | CTD | PMID:25181051 | Ssbp3 | Rat | bisphenol A | affects methylation | ISO | SSBP3 (Homo sapiens) | 6480464 | bisphenol A affects the methylation of SSBP3 gene | CTD | PMID:31601247 | Ssbp3 | Rat | bisphenol A | multiple interactions | ISO | SSBP3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of SSBP3 gene | CTD | PMID:31601247 | Ssbp3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SSBP3 mRNA | CTD | PMID:38750585 | Ssbp3 | Rat | cadmium atom | multiple interactions | ISO | Ssbp3 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SSBP3 mRNA | CTD | PMID:37325564 | Ssbp3 | Rat | cadmium dichloride | multiple interactions | ISO | Ssbp3 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SSBP3 mRNA | CTD | PMID:37325564 | Ssbp3 | Rat | caffeine | affects phosphorylation | ISO | SSBP3 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of SSBP3 protein | CTD | PMID:35688186 | Ssbp3 | Rat | calcium silicate | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | calcium silicate results in decreased expression of SSBP3 mRNA | CTD | PMID:29279043 | Ssbp3 | Rat | carbon nanotube | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Ssbp3 | Rat | CGP 52608 | multiple interactions | ISO | SSBP3 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SSBP3 gene] | CTD | PMID:28238834 | Ssbp3 | Rat | choline | multiple interactions | ISO | Ssbp3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of SSBP3 mRNA | CTD | PMID:20938992 | Ssbp3 | Rat | ciguatoxin CTX1B | affects expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of SSBP3 mRNA | CTD | PMID:18353800 | Ssbp3 | Rat | copper atom | multiple interactions | ISO | SSBP3 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of SSBP3 mRNA | CTD | PMID:20971185 | Ssbp3 | Rat | copper(0) | multiple interactions | ISO | SSBP3 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of SSBP3 mRNA | CTD | PMID:20971185 | Ssbp3 | Rat | crocidolite asbestos | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of SSBP3 mRNA | CTD | PMID:29279043 | Ssbp3 | Rat | cyclosporin A | decreases expression | ISO | SSBP3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of SSBP3 mRNA | CTD | PMID:20106945 | Ssbp3 | Rat | dexamethasone | multiple interactions | ISO | SSBP3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of SSBP3 mRNA | CTD | PMID:28628672 | Ssbp3 | Rat | diarsenic trioxide | decreases expression | ISO | SSBP3 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of SSBP3 mRNA | CTD | PMID:22521957 | Ssbp3 | Rat | diazinon | increases methylation | ISO | SSBP3 (Homo sapiens) | 6480464 | Diazinon results in increased methylation of SSBP3 gene | CTD | PMID:22964155 | Ssbp3 | Rat | Dibutyl phosphate | affects expression | ISO | SSBP3 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of SSBP3 mRNA | CTD | PMID:37042841 | Ssbp3 | Rat | dibutyl phthalate | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of SSBP3 mRNA | CTD | PMID:21266533 | Ssbp3 | Rat | diethylstilbestrol | decreases expression | EXP | | 6480464 | Diethylstilbestrol results in decreased expression of SSBP3 mRNA | CTD | PMID:36653537 | Ssbp3 | Rat | diquat | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Diquat results in decreased expression of SSBP3 protein | CTD | PMID:36851058 | Ssbp3 | Rat | doxorubicin | decreases expression | ISO | SSBP3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SSBP3 mRNA | CTD | PMID:29803840 | Ssbp3 | Rat | epoxiconazole | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of SSBP3 mRNA | CTD | PMID:35436446 | Ssbp3 | Rat | ethanol | affects splicing | ISO | Ssbp3 (Mus musculus) | 6480464 | Ethanol affects the splicing of SSBP3 mRNA | CTD | PMID:30319688 | Ssbp3 | Rat | fenthion | increases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Fenthion results in increased expression of SSBP3 mRNA | CTD | PMID:34813904 | Ssbp3 | Rat | folic acid | multiple interactions | ISO | Ssbp3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of SSBP3 mRNA | CTD | PMID:20938992 | Ssbp3 | Rat | FR900359 | affects phosphorylation | ISO | SSBP3 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of SSBP3 protein | CTD | PMID:37730182 | Ssbp3 | Rat | fulvestrant | multiple interactions | ISO | SSBP3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of SSBP3 gene and [bisphenol S co-treated with Fulvestrant] results in increased methylation of SSBP3 gene | CTD | PMID:31601247 | Ssbp3 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SSBP3 mRNA | CTD | PMID:22061828 and PMID:33387578 | Ssbp3 | Rat | indometacin | multiple interactions | ISO | SSBP3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of SSBP3 mRNA | CTD | PMID:28628672 | Ssbp3 | Rat | L-methionine | multiple interactions | ISO | Ssbp3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of SSBP3 mRNA | CTD | PMID:20938992 | Ssbp3 | Rat | lead diacetate | multiple interactions | ISO | SSBP3 (Homo sapiens) | 6480464 | [lead acetate co-treated with zinc protoporphyrin] results in increased expression of SSBP3 mRNA | CTD | PMID:22839698 | Ssbp3 | Rat | methapyrilene | decreases methylation | ISO | SSBP3 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of SSBP3 intron | CTD | PMID:30157460 | Ssbp3 | Rat | methidathion | increases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | methidathion results in increased expression of SSBP3 mRNA | CTD | PMID:34813904 | Ssbp3 | Rat | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of SSBP3 mRNA | CTD | PMID:25729387 | Ssbp3 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of SSBP3 mRNA | CTD | PMID:25729387 | Ssbp3 | Rat | paracetamol | affects expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SSBP3 mRNA | CTD | PMID:17562736 | Ssbp3 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of SSBP3 mRNA | CTD | PMID:32479839 and PMID:33387578 | Ssbp3 | Rat | PhIP | increases expression | EXP | | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of SSBP3 mRNA | CTD | PMID:15215175 | Ssbp3 | Rat | pirinixic acid | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of SSBP3 mRNA | CTD | PMID:18445702 | Ssbp3 | Rat | potassium chromate | decreases expression | ISO | SSBP3 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of SSBP3 mRNA | CTD | PMID:22079256 | Ssbp3 | Rat | potassium chromate | multiple interactions | ISO | SSBP3 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SSBP3 mRNA | CTD | PMID:22079256 | Ssbp3 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of SSBP3 mRNA | CTD | PMID:28903501 | Ssbp3 | Rat | propiconazole | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | propiconazole results in decreased expression of SSBP3 mRNA | CTD | PMID:21278054 | Ssbp3 | Rat | pyrogallol | increases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Pyrogallol results in increased expression of SSBP3 mRNA | CTD | PMID:20362636 | Ssbp3 | Rat | rac-lactic acid | decreases expression | ISO | SSBP3 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SSBP3 mRNA | CTD | PMID:30851411 | Ssbp3 | Rat | sodium arsenate | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of SSBP3 mRNA | CTD | PMID:30953684 | Ssbp3 | Rat | sodium arsenite | increases expression | ISO | SSBP3 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of SSBP3 mRNA | CTD | PMID:34032870 | Ssbp3 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of SSBP3 mRNA | CTD | PMID:31150632 | Ssbp3 | Rat | titanium dioxide | increases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of SSBP3 mRNA | CTD | PMID:29264374 | Ssbp3 | Rat | titanium dioxide | decreases methylation | ISO | Ssbp3 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of SSBP3 gene | CTD | PMID:35295148 | Ssbp3 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of SSBP3 mRNA | CTD | PMID:25729387 | Ssbp3 | Rat | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of SSBP3 mRNA | CTD | PMID:25729387 | Ssbp3 | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of SSBP3 mRNA | CTD | PMID:30589522 | Ssbp3 | Rat | triphenyl phosphate | affects expression | ISO | SSBP3 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of SSBP3 mRNA | CTD | PMID:37042841 | Ssbp3 | Rat | triptonide | affects expression | ISO | Ssbp3 (Mus musculus) | 6480464 | triptonide affects the expression of SSBP3 mRNA | CTD | PMID:33045310 | Ssbp3 | Rat | troglitazone | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | troglitazone results in decreased expression of SSBP3 mRNA | CTD | PMID:28973697 | Ssbp3 | Rat | tungsten | decreases expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Tungsten results in decreased expression of SSBP3 mRNA | CTD | PMID:30912803 | Ssbp3 | Rat | urethane | increases expression | ISO | SSBP3 (Homo sapiens) | 6480464 | Urethane results in increased expression of SSBP3 mRNA | CTD | PMID:28818685 | Ssbp3 | Rat | valproic acid | affects expression | ISO | Ssbp3 (Mus musculus) | 6480464 | Valproic Acid affects the expression of SSBP3 mRNA | CTD | PMID:17963808 | Ssbp3 | Rat | zinc protoporphyrin | multiple interactions | ISO | SSBP3 (Homo sapiens) | 6480464 | [lead acetate co-treated with zinc protoporphyrin] results in increased expression of SSBP3 mRNA | CTD | PMID:22839698 | |