Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Plin5 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PLIN5 mRNA | CTD | PMID:36331819 | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of PLIN5 mRNA | CTD | PMID:30723492 | 17beta-estradiol | increases expression | ISO | Plin5 (Mus musculus) | 6480464 | Estradiol results in increased expression of PLIN5 mRNA | CTD | PMID:19484750 | 17beta-estradiol | increases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | Estradiol results in increased expression of PLIN5 mRNA | CTD | PMID:31614463 | 17beta-estradiol | multiple interactions | ISO | PLIN5 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of PLIN5 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PLIN5 mRNA | CTD | PMID:19770486 more ... | 3,3',5,5'-tetrabromobisphenol A | multiple interactions | EXP | | 6480464 | tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA] | CTD | PMID:25048947 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | PLIN5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PLIN5 mRNA more ... | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | PLIN5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of PLIN5 mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | increases expression | ISO | Plin5 (Mus musculus) | 6480464 | Fenretinide results in increased expression of PLIN5 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of PLIN5 mRNA | CTD | PMID:24780913 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of PLIN5 mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of PLIN5 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | decreases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of PLIN5 mRNA | CTD | PMID:23724009 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of PLIN5 mRNA | CTD | PMID:30779732 | antirheumatic drug | decreases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of PLIN5 mRNA | CTD | PMID:24449571 | benzo[a]pyrene | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of PLIN5 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | decreases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of PLIN5 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | increases methylation | ISO | PLIN5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of PLIN5 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | PLIN5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of PLIN5 5' UTR | CTD | PMID:27901495 | benzo[b]fluoranthene | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in decreased expression of PLIN5 mRNA | CTD | PMID:26377693 | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of PLIN5 promoter | CTD | PMID:23359474 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of PLIN5 mRNA | CTD | PMID:31163220 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of PLIN5 promoter | CTD | PMID:23359474 | bisphenol A | increases expression | ISO | Plin5 (Mus musculus) | 6480464 | bisphenol A results in increased expression of PLIN5 mRNA | CTD | PMID:32156529 and PMID:33221593 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PLIN5 mRNA | CTD | PMID:34947998 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of PLIN5 gene | CTD | PMID:28505145 | bisphenol A | multiple interactions | ISO | PLIN5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PLIN5 mRNA | CTD | PMID:28628672 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of PLIN5 mRNA | CTD | PMID:32479839 | cantharidin | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | Cantharidin results in decreased expression of PLIN5 mRNA | CTD | PMID:36907384 | carbon nanotube | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of PLIN5 mRNA | CTD | PMID:25554681 | carbon nanotube | increases expression | ISO | Plin5 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of PLIN5 mRNA | CTD | PMID:25620056 | clofibrate | increases expression | ISO | Plin5 (Mus musculus) | 6480464 | Clofibrate results in increased expression of PLIN5 mRNA | CTD | PMID:23811191 | clofibrate | increases expression | EXP | | 6480464 | Clofibrate results in increased expression of PLIN5 mRNA | CTD | PMID:32741897 | copper(II) sulfate | increases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of PLIN5 mRNA | CTD | PMID:19549813 | crocidolite asbestos | decreases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in decreased expression of PLIN5 mRNA | CTD | PMID:29523930 | cyclosporin A | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of PLIN5 mRNA | CTD | PMID:19770486 | cyproconazole | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | cyproconazole results in decreased expression of PLIN5 mRNA | CTD | PMID:22334560 | dexamethasone | multiple interactions | ISO | PLIN5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PLIN5 mRNA more ... | CTD | PMID:28628672 | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of PLIN5 promoter | CTD | PMID:23359474 | dichloroacetic acid | increases expression | ISO | Plin5 (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of PLIN5 mRNA | CTD | PMID:28962523 | dicrotophos | decreases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of PLIN5 mRNA | CTD | PMID:28302478 | diquat | increases expression | ISO | Plin5 (Mus musculus) | 6480464 | Diquat results in increased expression of PLIN5 mRNA | CTD | PMID:36851058 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of PLIN5 mRNA | CTD | PMID:29391264 | epoxiconazole | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of PLIN5 mRNA | CTD | PMID:22334560 and PMID:35436446 | fenofibrate | increases expression | EXP | | 6480464 | Fenofibrate results in increased expression of PLIN5 mRNA | CTD | PMID:32741897 | genistein | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | Genistein results in decreased expression of PLIN5 mRNA | CTD | PMID:32186404 | hexadecanoic acid | multiple interactions | EXP | | 6480464 | [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA and tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA] | CTD | PMID:25048947 | indometacin | multiple interactions | ISO | PLIN5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PLIN5 mRNA more ... | CTD | PMID:28628672 | inulin | multiple interactions | ISO | Plin5 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PLIN5 mRNA | CTD | PMID:36331819 | lead diacetate | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | lead acetate results in decreased expression of PLIN5 mRNA | CTD | PMID:25270620 | Licochalcone B | increases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | licochalcone B results in increased expression of PLIN5 mRNA | CTD | PMID:33647349 | Mesaconitine | decreases expression | EXP | | 6480464 | mesaconitine results in decreased expression of PLIN5 protein | CTD | PMID:37182599 | methidathion | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | methidathion results in decreased expression of PLIN5 mRNA | CTD | PMID:34813904 | methylmercury chloride | increases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of PLIN5 mRNA | CTD | PMID:28001369 | mono(2-ethylhexyl) phthalate | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of PLIN5 mRNA | CTD | PMID:22401849 | Muraglitazar | increases expression | EXP | | 6480464 | muraglitazar results in increased expression of PLIN5 mRNA | CTD | PMID:21515302 | N-Nitrosopyrrolidine | decreases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in decreased expression of PLIN5 mRNA | CTD | PMID:32234424 | nickel atom | decreases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | Nickel results in decreased expression of PLIN5 mRNA | CTD | PMID:24768652 | oleic acid | multiple interactions | EXP | | 6480464 | [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA and tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA] | CTD | PMID:25048947 | paracetamol | increases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PLIN5 mRNA | CTD | PMID:21420995 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PLIN5 mRNA | CTD | PMID:32479839 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Plin5 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PLIN5 mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PLIN5 mRNA | CTD | PMID:36331819 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of PLIN5 mRNA | CTD | PMID:28511854 | phenobarbital | affects expression | ISO | Plin5 (Mus musculus) | 6480464 | Phenobarbital affects the expression of PLIN5 mRNA | CTD | PMID:23091169 | pirinixic acid | multiple interactions | ISO | Plin5 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PLIN5 mRNA | CTD | PMID:19710929 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of PLIN5 mRNA | CTD | PMID:32741897 | pirinixic acid | increases expression | ISO | Plin5 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of PLIN5 mRNA | CTD | PMID:23811191 | propiconazole | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | propiconazole results in decreased expression of PLIN5 mRNA | CTD | PMID:22334560 | sodium arsenite | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of PLIN5 mRNA | CTD | PMID:25270620 | sodium arsenite | decreases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PLIN5 mRNA | CTD | PMID:29301061 | sulforaphane | increases expression | ISO | Plin5 (Mus musculus) | 6480464 | sulforaphane results in increased expression of PLIN5 mRNA | CTD | PMID:30529165 | sunitinib | increases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PLIN5 mRNA | CTD | PMID:31533062 | tamoxifen | affects expression | ISO | Plin5 (Mus musculus) | 6480464 | Tamoxifen affects the expression of PLIN5 mRNA | CTD | PMID:20937368 | temozolomide | decreases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of PLIN5 mRNA | CTD | PMID:31758290 | Tesaglitazar | increases expression | EXP | | 6480464 | tesaglitazar results in increased expression of PLIN5 mRNA | CTD | PMID:21515302 | tetrachloromethane | increases expression | ISO | Plin5 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of PLIN5 mRNA | CTD | PMID:31919559 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of PLIN5 mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | Plin5 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of PLIN5 mRNA | CTD | PMID:23557971 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of PLIN5 mRNA | CTD | PMID:33387578 | trichostatin A | affects expression | ISO | PLIN5 (Homo sapiens) | 6480464 | trichostatin A affects the expression of PLIN5 mRNA | CTD | PMID:28542535 | triclosan | decreases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of PLIN5 mRNA | CTD | PMID:30510588 | triphenyl phosphate | decreases expression | EXP | | 6480464 | triphenyl phosphate results in decreased expression of PLIN5 mRNA | CTD | PMID:30589522 | triptonide | increases expression | ISO | Plin5 (Mus musculus) | 6480464 | triptonide results in increased expression of PLIN5 mRNA | CTD | PMID:33045310 | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of PLIN5 mRNA | CTD | PMID:21515302 | urethane | increases expression | ISO | PLIN5 (Homo sapiens) | 6480464 | Urethane results in increased expression of PLIN5 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | Plin5 (Mus musculus) | 6480464 | Valproic Acid affects the expression of PLIN5 mRNA | CTD | PMID:17292431 | |