Ugt8 (UDP glycosyltransferase 8) - Rat Genome Database

Name: Ugt8
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Ugt8 (UDP glycosyltransferase 8) Rattus norvegicus

Analyze

Symbol:

Ugt8

Name:

UDP glycosyltransferase 8

RGD ID:

3938

Description:

Exhibits UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity. Predicted to be involved in cytoskeleton organization; nervous system development; and protein localization to paranode region of axon. Predicted to localize to intracellular membrane-bounded organelle. Orthologous to human UGT8 (UDP glycosyltransferase 8); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil; ammonium chloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

2-hydroxyacylsphingosine 1-beta-galactosyltransferase; ceramide UDP-galactosyltransferase; cerebroside synthase; CGalT; UDP galactosyltransferase 8; UDP galactosyltransferase 8A; UDP-galactose-ceramide galactosyltransferase 8; UDP-glucuronosyltransferase 8; Ugt8a

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UGT8 (UDP glycosyltransferase 8)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ugt8a (UDP galactosyltransferase 8A)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Ugt8 (UDP glycosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	UGT8 (UDP glycosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	UGT8 (UDP glycosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ugt8 (UDP glycosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	UGT8 (UDP glycosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	UGT8 (UDP glycosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ugt8 (UDP glycosyltransferase 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	UGT8 (UDP glycosyltransferase 8)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Ugt8a (UDP galactosyltransferase 8A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	ugt8 (UDP glycosyltransferase 8)	Alliance	DIOPT (PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	CG10170	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG16732	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-62	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG30438	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-58	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	ATG26	Alliance	DIOPT (Ensembl Compara\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt37c1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt86Dc	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt86Di	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG5724	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt37a1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt37b1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt36Bb	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG3797	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-61	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt36Ba	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt36Bc	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt86Da	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	214,264,483 - 214,332,769 (-)	NCBI
Rnor_6.0 Ensembl	2	229,644,382 - 229,718,659 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	2	229,644,373 - 229,718,678 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	2	248,998,871 - 249,072,741 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	222,977,966 - 223,048,277 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	36,844,752 - 36,845,448 (+)	NCBI
Celera	2	206,609,425 - 206,656,289 (-)	NCBI		Celera
Cytogenetic Map	2	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-diaminodiphenylmethane (ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

arsenite(3-) (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium atom (ISO)

carmustine (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

dibutyl phthalate (EXP)

dorsomorphin (ISO)

entinostat (ISO)

ethanol (ISO)

fenvalerate (EXP)

flavonoids (EXP)

glycidol (EXP)

haloperidol (ISO)

hexachlorobenzene (EXP)

lead diacetate (EXP)

methylmercury chloride (ISO)

nickel atom (ISO)

panobinostat (ISO)

paracetamol (ISO)

paraquat (ISO)

PD 0325901 (ISO)

phenobarbital (EXP)

potassium chromate (ISO)

rotenone (EXP)

SB 431542 (ISO)

sunitinib (ISO)

Testosterone propionate (ISO)

thimerosal (ISO)

titanium dioxide (ISO)

topotecan (EXP)

Tributyltin oxide (ISO)

trichostatin A (ISO)

valproic acid (EXP,ISO)

vitamin E (ISO)

vorinostat (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cytoskeleton organization (ISO)

galactosylceramide biosynthetic process (IDA,IEA)

glycosphingolipid biosynthetic process (TAS)

myelination (TAS)

neuron projection morphogenesis (ISO)

paranodal junction assembly (ISO)

protein localization to paranode region of axon (ISO)

Cellular Component

endoplasmic reticulum (IDA)

integral component of membrane (IEA)

intracellular membrane-bounded organelle (IBA)

Molecular Function

2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity (IDA)

N-acylsphingosine galactosyltransferase activity (IEA)

UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity (IMP)

Molecular Pathway Annotations Click to see Annotation Detail View

Fabry disease pathway (ISO)

Gaucher's disease pathway (ISO)

Krabbe disease pathway (ISO)

metachromatic leukodystrophy pathway (ISO)

sphingolipid metabolic pathway (IEA,ISO)

References

References - curated


1.	Coetzee T, etal., Cell 1996 Jul 26;86(2):209-19.
2.	Dupree JL, etal., J Neurosci 1998 Mar 1;18(5):1642-9.
3.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	GOA data from the GO Consortium
5.	MGD data from the GO Consortium
6.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	Pipeline to import KEGG annotations from KEGG into RGD
8.	Pipeline to import SMPDB annotations from SMPDB into RGD
9.	RGD automated data pipeline
10.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	RGD automated import pipeline for gene-chemical interactions
12.	Schulte S and Stoffel W, Proc Natl Acad Sci U S A 1993 Nov 1;90(21):10265-9.
13.	Stahl N, etal., J Neurosci Res 1994 Jun 1;38(2):234-42.
14.	van der Bijl P, etal., Biochem J. 1996 Jul 15;317 ( Pt 2):589-97. doi: 10.1042/bj3170589.

Additional References at PubMed

PMID:8889548	PMID:12060780	PMID:16551741

Genomics

Comparative Map Data

Ugt8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	214,264,483 - 214,332,769 (-)	NCBI
Rnor_6.0 Ensembl	2	229,644,382 - 229,718,659 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	2	229,644,373 - 229,718,678 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	2	248,998,871 - 249,072,741 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	222,977,966 - 223,048,277 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	36,844,752 - 36,845,448 (+)	NCBI
Celera	2	206,609,425 - 206,656,289 (-)	NCBI		Celera
Cytogenetic Map	2	q42	NCBI

UGT8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	4	114,598,770 - 114,678,225 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	4	114,598,402 - 114,687,914 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	4	115,519,558 - 115,599,381 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	4	115,519,611 - 115,598,202 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	115,762,972 - 115,817,201 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	4	115,901,126 - 115,955,356	NCBI
Celera	4	112,813,079 - 112,891,640 (+)	NCBI
Cytogenetic Map	4	q26	NCBI
HuRef	4	111,253,852 - 111,332,365 (+)	NCBI		HuRef
CHM1_1	4	115,496,024 - 115,575,814 (+)	NCBI		CHM1_1

Ugt8a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	125,655,071 - 125,732,301 (-)	NCBI	GRCm39		mm39
GRCm38	3	125,865,272 - 125,938,682 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	125,865,271 - 125,938,619 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	125,568,261 - 125,641,468 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	3	125,857,534 - 125,907,483 (-)	NCBI			mm8
Celera	3	132,313,587 - 132,366,589 (-)	NCBI		Celera
Cytogenetic Map	3	G1	NCBI

Ugt8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955428	24,800,854 - 24,865,378 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955428	24,800,854 - 24,864,904 (-)	NCBI	ChiLan1.0	ChiLan1.0

UGT8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	4	117,676,804 - 117,762,363 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	117,676,810 - 117,762,729 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	4	107,113,476 - 107,199,272 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

UGT8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	32	34,179,247 - 34,233,116 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	32	34,148,874 - 34,250,891 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Ugt8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936563	5,251,451 - 5,305,683 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UGT8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	108,233,139 - 108,314,921 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	108,233,134 - 108,315,284 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	115,965,708 - 115,974,792 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UGT8
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	62,380,506 - 62,465,695 (+)	NCBI
ChlSab1.1 Ensembl	7	62,381,223 - 62,466,401 (+)	Ensembl

Ugt8
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624867	1,182,674 - 1,255,714 (+)	NCBI

Position Markers

X92122

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	2	229,646,033 - 229,646,180	NCBI	Rnor6.0
Rnor_5.0	2	249,000,425 - 249,000,572	UniSTS	Rnor5.0
RGSC_v3.4	2	222,979,520 - 222,979,667	UniSTS	RGSC3.4
Celera	2	206,610,979 - 206,611,126	UniSTS
Cytogenetic Map	2	q42	UniSTS

RH136801

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	2	229,644,645 - 229,644,764	NCBI	Rnor6.0
Rnor_5.0	2	248,999,037 - 248,999,156	UniSTS	Rnor5.0
RGSC_v3.4	2	222,978,132 - 222,978,251	UniSTS	RGSC3.4
Celera	2	206,609,591 - 206,609,710	UniSTS
RH 3.4 Map	2	1546.6	UniSTS
Cytogenetic Map	2	q42	UniSTS

Ugt8a

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	2	229,646,338 - 229,646,599	NCBI	Rnor6.0
Rnor_5.0	2	249,000,730 - 249,000,991	UniSTS	Rnor5.0
RGSC_v3.4	2	222,979,825 - 222,980,086	UniSTS	RGSC3.4
Celera	2	206,611,284 - 206,611,545	UniSTS
Cytogenetic Map	2	q42	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631203	Gluco14	Glucose level QTL 14		0.0001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	2	221880206	235570970	Rat
61458	Bp10	Blood pressure QTL 10	3.42		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	204003742	231132207	Rat
61469	Bp16	Blood pressure QTL 16	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	184730446	229730446	Rat
70162	Bp63	Blood pressure QTL 63	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	184730446	229730446	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	181990297	240020001	Rat
1331745	Bp203	Blood pressure QTL 203	4.377		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	204585642	235290110	Rat
1298075	Scl17	Serum cholesterol level QTL 17	3.4		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	228712271	266435125	Rat
1298083	Bp158	Blood pressure QTL 158	2.62		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	204003742	231132207	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	147122993	240020001	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	147122993	240020001	Rat
1581499	Esta2	Estrogen-induced thymic atrophy QTL 2			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	204585642	243689611	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	199380312	244380312	Rat
1300126	Bp175	Blood pressure QTL 175	3.46		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	229606682	264899009	Rat
1302789	Stl26	Serum triglyceride level QTL 26	3.1	0.0035	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	218957047	240977220	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	155965557	254121739	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	155965557	237742948	Rat
1598813	Memor9	Memory QTL 9	2.7		exploratory behavior trait (VT:0010471)	average horizontal distance in proximity to the target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	214870793	251212353	Rat
1598835	Anxrr18	Anxiety related response QTL 18	2.98		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	2	217743855	262743855	Rat
2301408	Kidm36	Kidney mass QTL 36		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	205583921	243562243	Rat
2298479	Eau5	Experimental allergic uveoretinitis QTL 5		0.0021	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	2	217498545	254132424	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	194378622	239378622	Rat
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	175403337	239166203	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	83819608	239166203	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66828236	243550655	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83819608	243901375	Rat
2299161	Iddm33	Insulin dependent diabetes mellitus QTL 33	2.98		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	221488355	254121739	Rat
1549836	Bss2	Bone structure and strength QTL 2	7.5		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	2	228712271	266435125	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	177680772	243901375	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	200453324	236318668	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	200453324	236318668	Rat
2317752	Glom23	Glomerulus QTL 23	3.6		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	2	208594330	263179188	Rat
61366	Iddm3	Insulin dependent diabetes mellitus QTL 3	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	204585642	249585642	Rat
61398	Bp50	Blood pressure QTL 50	4.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	204585642	249585642	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	194998627	239998627	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	197253963	242253963	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	197253963	242253963	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	197253963	242253963	Rat
7207490	Bss111	Bone structure and strength QTL 111	6.4		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	2	228712271	266435125	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	169852670	243026643	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	83754907	237610852	Rat
7207482	Bss107	Bone structure and strength QTL 107	7		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	2	228712271	266435125	Rat
7207484	Bss108	Bone structure and strength QTL 108	5.3		femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	2	228712271	266435125	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	197253963	242253963	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	16679272	245624402	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	520
Count of miRNA genes:	275
Interacting mature miRNAs:	338
Transcripts:	ENSRNOT00000012676
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1						2	2	33	14	4		2
Low	2	16	16	12	5	12	5	5	41	21	36	10	5
Below cutoff		24	29	17	13	17	1	4			1	1	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_019276	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591052	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BF551096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BG671666	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L21698	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000012676 ⟹ ENSRNOP00000012676

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	2	229,644,382 - 229,718,659 (-)	Ensembl

RefSeq Acc Id:

NM_019276 ⟹ NP_062149

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	214,264,483 - 214,332,660 (-)	NCBI
Rnor_6.0	2	229,644,479 - 229,718,672 (-)	NCBI
Rnor_5.0	2	248,998,871 - 249,072,741 (-)	NCBI
RGSC_v3.4	2	222,977,966 - 223,048,277 (-)	RGD
Celera	2	206,609,425 - 206,656,289 (-)	RGD

Sequence:

show sequence

CTCGCTCCACAGACACCGTCCCGCGGCAGAGGCGCTTTCCAACTCCCGCGCAGCAGCCGAAGGA
CGCGCTATGAAGTCTTATACTCCATATTTCATGCTCCTGTGGAGTGCTGTTGGAATAGCAAGGG
CTGCTAAAATCATCATTGTGCCGCCAATTATGTTTGAAAGCCATTTGTACATTTTCAAGACACT
AGCATCAGCCTTGCACGAGAGAGGCCATCACACTGTGTTCCTCCTCTCAGAAGGCAGAGACATT
GACCCATCTAATCACTACAGCCTCCAGCGATACCCAGGGATCTTCAACAGTACCACCTCAGATG
CTTTCCTGCAGTCTAAAATGCGGAATATTTTCTCTGGAAGATTGACAGCAGTTGAACTGGTTGA
CATACTGGATCACTATACTAAGAATTGTGACATGATGGTTGGCAACCAAGCCCTAATCCAGGGT
TTGAAAAAAGAAAAGTTTGACCTGCTACTGGTTGACCCCAATGATATGTGTGGATTTGTGATCG
CTCATCTTTTAGGCGTTAAGTATGCTGTGTTTTCTACTGGCCTTTGGTATCCTGCTGAAGTTGG
AGCGCCTGCTCCTTTAGCTTATGTCCCAGAGTTTAACTCACTCCTCACAGACCGCATGAACTTC
CTGGAAAGGATGAAAAATACAGGCGTTTACCTCATATCCAGAATGGGGGTTAGCTTTCTGGTTC
TTCCGAAATATGAAAGGATAATGCAGAAGTACAACCTGCTCCCTGCAAAGTCCATGTATGATTT
GGTTCATGGGTCCAGCTTGTGGATGTTATGTACTGACGTAGCACTGGAGTTTCCAAGGCCCACC
CTGCCTAACGTTGTATATGTTGGAGGAATCCTAACAAAGCCGGCCAGCCCACTGCCAGAAGATC
TGCAGAGGTGGGTAGATGGTGCTCAGGAGCATGGCTTTGTCCTGGTATCTTTTGGAGCTGGTGT
CAAGTATCTGTCAGAAGACATTGCTAACAAACTGGCAGGAGCTCTGGGGAGATTGCCTCAGAAA
GTGATTTGGAGGTTTTCTGGAACCAAACCAAAGAACCTAGGAAACAACACTAAGCTCATAGAAT
GGTTACCTCAAAATGACCTGCTTGGCCATTCAAACATCAGAGCCTTCCTAAGCCATGGTGGTTT
GAACAGTATATTTGAAACTATGTATCATGGTGTCCCTGTAGTAGGAATCCCACTCTTTGGAGAC
CATTATGATACTATGACTAGAGTACAGGCGAAAGGCATGGGGATCTTGTTAGAATGGAATACAG
TTACTGAAGGGGAGCTGTATGATGCACTGGTGAAAGTTATCAACAATCCCAGTTATCGGCAGAG
GGCTCAGAAGTTATCGGAAATTCATAAGGATCAACCCGGCCACCCTGTCAATCGGACTACCTAT
TGGATAGACTACATTCTTCGCCACGACGGAGCCCATCACCTCCGTTCGGCTGTCCATCAGATCT
CCTTCTGTCAGTATTTTCTACTGGATATTGCCTTTGTGCTTCTGCTTGGTGCTGTCGCGCTCTA
CTTCATAGTGTCCTATGTGACAAAATTTATCTATAGAAAAGTCAAAAGTCTGTGTTCTAGGAGT
ACGCACAGCACAGTTAATGGACACTACCAAAATGGAATCCTCAATGGCAGATACAAAGGAAATG
GTCATATTAAACATGAAAAAAAGGTAAAATGAGCCAACAGCCCAGGCGACGGGAGCAGATATGT
CTGGTCATTGAGTTTGTAGTGCTACTCTTTAGTCTAACAGCTACCAAAACTAAATGTCAGCAAA
CAATCCTAACACCCTCATCAGACCCTGTTAATGAAATCCATGGATAAAATGTCTGTACAGAGCA
CAACCCCAAGTGCAAAAATGTATTTTATTCTAACACTGATGCAGAAAGTTGGCAGTGAACCATT
TAGAAGCCTTAATTATTTAAATCAATTAAGTGATTGTGTCGGACCTGAGTTTTAAGTGTTATGT
ATGTATTACAGGTGAGGGATGGTGTTTTTCTCTTGATAAGATGCGTGTATGTTTCCCGTGTCGT
TGAGTTTTAGCTTCCATTTGTATTTAGCTTGTAACAGTATTTCAAAGACTGTTTCCTAAACTCA
GTGTAACGAGGCAAGTGAAAGATGGGTGGCACAGTTTTTGTATTTTTGTTTATTATAGACATTT
TTATTTTTTTCTTTTGTATATGCTTTTTTCTTACCAACTATGGATACTTGCGAAGGAAACTCGT
AATGAAGTAACTGAGTAAAAAGGTTTTCACATTTTTTTCTAATATTTTCCTCCTACCAATAATT
TTTCTCCAGAAGAATTTTCTAATTAGGACAAAGCAACAAAGCTCTTACTTTTGTTCAAAGTACT
GAAGAGTACGGCTCAAACAGCACTTGGAAGCAGAGCCATGTGCAAATGCTTGTGTGACTTGGAT
ATCCCATCATTTGAGTTTGAATATTCAGGTATCAACTTCTAAAATTTTAGCTTTAAAATAATCA
CCTCTCATTCCTTTTATTATCTGGGTCACGATATAGTACATAGGTGCCAACATATAATTCCTCT
TAAGCAGAACATTTGCGTTTCTCCTCCTTGGTACCTGGTTTGACTGCAGGAGTTTGAAGTTTGT
CAGCAAACAAGACTTCCCATGCGAACAGAAGTGACAGAAATTGTGCCACCCATTTGTGCAATGA
GTTCCCGTTCCCTCCTCACTCCATCAGCCCAACTCGGTAGCCTTTTTGGTCATTGTGCTTGACA
CGGGACAGTAAGAGTATCTATTTGGAACAGGGAGACGAGTCACAACGTTCATAAATTCAGGACC
TCCCTGTTGAACCACTTACTAAACGGCAACTGTAAGCTTATTCTACGTCACTGTGTTTACTGAG
CATTTGCACTGCACATGCGGAGTGTGTGCTTTATTTATTTGTGGTTGGAAATCCCACCCTTGAC
ACTTGAGAGTAGAGAAATGAAATATTTACTTAACGTCACTCACCAACCTGGCAGAGTTGTGAAA
AATCTAGAATGCTGTAAATCCTTGTCATACACTGTGACATACAACTTTGTGACACTCCCACCAG
GAGCCAGTCTCATGTACTTAGATATCACCAGTTTTTTAATGCACAGTGCATACAGCCTACTGCT
TTCTGAATACTTGAAATGGTATCTGTACACACCAGTTAGCTACTCCTTTTCACAATCTTATCAC
AATGTTGCCGTTCAAAGAGGAAAAAAGATCAGGCAATGAATGGTGGGGCAGCAGAGCATAGAGT
GTATGAACGAGCTGAGTTTACTTTTGGCATTTGATAAAGTTGGTAATAGGCACTAACTGGATGA
TTAAACATAAGTTAATTTCCACTGTGATTTAAAAAAAAACTTAAAACAATAAACAAAGTTGAAA
ATAGAAAAATGTTGTTGGAATAAAATTTTTATTCGGATTTTATTTTACAGTATTATATATAGGT
ATATTTACATTATAAACATGTTTCT

hide sequence

RefSeq Acc Id:

XM_017591052 ⟹ XP_017446541

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	214,266,268 - 214,332,769 (-)	NCBI
Rnor_6.0	2	229,644,373 - 229,718,678 (-)	NCBI

Sequence:

show sequence

GGCGCGCTCGCTCCACAGACACCGTCCCGCGGCAGAGGCGCTTTCCAACTCCCGCGCAGCAGCC
GAAGGACGCGGTAAGCGGCGGGCGTCGGCAGGGGCACGGGGACGGAGGGCTCCGGGACACAGTT
GTTCTCCGCCCGAGCTATGAAGTCTTATACTCCATATTTCATGCTCCTGTGGAGTGCTGTTGGA
ATAGCAAGGGCTGCTAAAATCATCATTGTGCCGCCAATTATGTTTGAAAGCCATTTGTACATTT
TCAAGACACTAGCATCAGCCTTGCACGAGAGAGGCCATCACACTGTGTTCCTCCTCTCAGAAGG
CAGAGACATTGACCCATCTAATCACTACAGCCTCCAGCGATACCCAGGGATCTTCAACAGTACC
ACCTCAGATGCTTTCCTGCAGTCTAAAATGCGGAATATTTTCTCTGGAAGATTGACAGCAGTTG
AACTGGTTGACATACTGGATCACTATACTAAGAATTGTGACATGATGGTTGGCAACCAAGCCCT
AATCCAGGGTTTGAAAAAAGAAAAGTTTGACCTGCTACTGGTTGACCCCAATGATATGTGTGGA
TTTGTGATCGCTCATCTTTTAGGCGTTAAGTATGCTGTGTTTTCTACTGGCCTTTGGTATCCTG
CTGAAGTCGGAGCGCCTGCTCCTTTAGCTTATGTCCCAGAGTTTAACTCACTCCTCACAGACCG
CATGAACTTCCTGGAAAGGATGAAAAATACAGGCGTTTACCTCATATCCAGAATGGGGGTTAGC
TTTCTGGTTCTTCCGAAATATGAAAGGATAATGCAGAAGTACAACCTGCTCCCTGCAAAGTCCA
TGTATGATTTGGTTCATGGGTCCAGCTTGTGGATGTTATGTACTGACGTAGCACTGGAGTTTCC
AAGGCCCACCCTGCCTAACGTTGTATATGTTGGAGGAATCCTAACAAAGCCGGCCAGCCCACTG
CCAGAAGATCTGCAGAGGTGGGTAGATGGTGCTCAGGAGCATGGCTTTGTCCTGGTATCTTTTG
GAGCTGGTGTCAAGTATCTGTCAGAAGACATTGCTAACAAACTGGCAGGAGCTCTGGGGAGATT
GCCTCAGAAAGTGATTTGGAGGTTTTCTGGAACCAAACCAAAGAACCTAGGAAACAACACTAAG
CTCATAGAATGGTTACCTCAAAATGACCTGCTTGGCCATTCAAACATCAGAGCCTTCCTAAGCC
ATGGTGGTTTGAACAGTATATTTGAAACTATGTATCATGGTGTCCCTGTAGTAGGAATCCCACT
CTTTGGAGACCATTATGATACTATGACTAGAGTACAGGCGAAAGGCATGGGGATCTTGTTAGAA
TGGAATACAGTTACTGAAGGGGAGCTGTATGATGCACTGGTGAAAGTTATCAACAATCCCAGTT
ATCGGCAGAGGGCTCAGAAGTTATCGGAAATTCATAAGGATCAACCCGGCCACCCTGTCAATCG
GACTACCTATTGGATAGACTACATTCTTCGCCACGACGGAGCCCATCACCTCCGTTCGGCTGTC
CATCAGATCTCCTTCTGTCAGTATTTTCTACTGGATATTGCCTTTGTGCTTCTGCTTGGTGCTG
TCGCGCTCTACTTCATAGTGTCCTATGTGACAAAATTTATCTATAGAAAAGTCAAAAGTCTGTG
TTCTAGGAGTACGCACAGCACAGTTAATGGACACTACCAAAATGGAATCCTCAATGGCAGATAC
AAAGGAAATGGTCATATTAAACATGAAAAAAAGGTAAAATGAGCCAACAGCCCAGGCGACGGGA
GCAGATATGTCTGGTCATTGAGTTTGTAGTGCTACTCTTTAGTCTAACAGCTACCAAAACTAAA
TGTCAGCAAACAATCCTAACACCCTCATCAGACCCTGTTAATGAAATCCATGGATAAAATGTCT
GTACAGAGCACAACCCCAAGTGCAAAAATGTATTTTATTCTAACACTGATGCAGAAAGTTGGCA
GTGAACCATTTAGAAGCCTTAATTATTTAAATCAATTAAGTGATTGTGTCGGACCTGAGTTTTA
AGTGTTATGTATGTATTACAGGTGAGGGATGGTGTTTTTCTCTTGATAAGATGCGTGTATGTTT
CCCGTGTCGTTGAGTTTTAGCTTCCATTTGTATTTAGCTTGTAACAGTATTTCAAAGACTGTTT
CCTAAACTCAGTGTAACGAGGCAAGTGAAAGATGGGTGGCACAGTTTTTGTATTTTTGTTTATT
ATAGACATTTTTATTTTTTTCTTTTGTATATGCTTTTTTCTTACCAACTATGGATACTTGCGAA
GGAAACTTGTAATGAAGTAACTGAGTAAAAAGGTTTTCACATTTTTTTCTAATATTTTCCTCCT
ACCAATAATTTTTCTCCAGAAGAATTTTCTAATTAGGACAAAGCAACAAAGCTCTTACTTTTGT
TCAAAGTACTGAAGAGTACGGCTCAAACAGCACTTGGAAGCAGAGCCATGTGCAAATGCTTGTG
TGACTTGGATATCCCATCATTTGAGTTTGAATATTCAGGTATCAACTTCTAAAATTTTAGCTTT
AAAATAATCACCTCTCATTCCTTTTATTATCTGGGTCACGATATAGTACATAGGTGCCAACATA
TAATTCCTCTTAAGCAGAACATTTGCGTTTCTCCTCCTTGGTACCTGGTTTGACTGCAGGAGTT
TGAAGTTTGTCAGCAAACAAGACTTCCCATGCGAACAGAAGTGACAGAAATTGTGCCACCCATT
TGTGCAATGAGTTCCCGTTCCCTCCTCACTCCATCAGCCCAACTCGGTAGCCTTTTTGGTCATT
GTGCTTGACACGGGACAGTAAGAGTATCTATTTGGAACAGGGAGACGAGTCACAACGTTCATAA
ATTCAGGACCTCCCTGTTGAACCACTTACTAAACGGCAACTGTAAGCTTATTCTACGTCACTGT
GTTTACTGAGCATTTGCACTGCACATGCGGAGTGTGTGCTTTATTTATTTGTGGTTGGAAATCC
CACCCTTGACACTTGAGAGTAGAGAAATGAAATATTTAGTTAACGTCACTCACCAACCTGGCAG
AGTTGTGAAAAATCTAGAATGCTGTAAATCCTTGTCATACACTGTGACATACAACTTTGTGACA
CTCCCACCAGGAGCCAGTCTCATGTACTTAGATATCACCAGTTTTTTAATGCACAGTGCATACA
GCCTACTGCTTTCTGAATACTTGAAATGGTATCTGTACACACCAGTTAGCTACTCCTTTTCACA
ATCTTATCACAATGTTGCCGTTCAAAGAGGAAAAAAGATCAGGCAATGAATGGTGGGGCAGCAG
AGCATAGAGTGTATGAACGAGCTGAGTTTACTTTTGGCATTTGATAAAGTTGGTAATAGGCACT
AACTGGATGATTAAACATAAGTTAATTTCCACTGTGATTTAAAAAAAAACTTAAAACAATAAAC
AAAGTTGAAAATAGAAAAATGTTGTTGGAATAAAATTTTTATTCGGATTTTATTTTACAGTATT
ATATATAGGTATATTTACATTATAAACATGTTTCTAAGGCCTCCCAACTTTTGTATGTATATAT
GAATGTGAAAACAATGTATTAAATGTGAGAACATATTTAATAAAAATTAAATGCAGGGATTTAT
CCTTTTAAGAACA

hide sequence

Protein Sequences


Protein RefSeqs	NP_062149	(Get FASTA)	NCBI Sequence Viewer
	XP_017446541	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA16108	(Get FASTA)	NCBI Sequence Viewer
	EDL82139	(Get FASTA)	NCBI Sequence Viewer
	EDL82140	(Get FASTA)	NCBI Sequence Viewer
	Q09426	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_062149 ⟸ NM_019276
- Peptide Label:	precursor
- UniProtKB:	Q09426 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MKSYTPYFMLLWSAVGIARAAKIIIVPPIMFESHLYIFKTLASALHERGHHTVFLLSEGRDIDP SNHYSLQRYPGIFNSTTSDAFLQSKMRNIFSGRLTAVELVDILDHYTKNCDMMVGNQALIQGLK KEKFDLLLVDPNDMCGFVIAHLLGVKYAVFSTGLWYPAEVGAPAPLAYVPEFNSLLTDRMNFLE RMKNTGVYLISRMGVSFLVLPKYERIMQKYNLLPAKSMYDLVHGSSLWMLCTDVALEFPRPTLP NVVYVGGILTKPASPLPEDLQRWVDGAQEHGFVLVSFGAGVKYLSEDIANKLAGALGRLPQKVI WRFSGTKPKNLGNNTKLIEWLPQNDLLGHSNIRAFLSHGGLNSIFETMYHGVPVVGIPLFGDHY DTMTRVQAKGMGILLEWNTVTEGELYDALVKVINNPSYRQRAQKLSEIHKDQPGHPVNRTTYWI DYILRHDGAHHLRSAVHQISFCQYFLLDIAFVLLLGAVALYFIVSYVTKFIYRKVKSLCSRSTH STVNGHYQNGILNGRYKGNGHIKHEKKVK hide sequence

RefSeq Acc Id:	XP_017446541 ⟸ XM_017591052
- Peptide Label:	isoform X1
- UniProtKB:	Q09426 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MKSYTPYFMLLWSAVGIARAAKIIIVPPIMFESHLYIFKTLASALHERGHHTVFLLSEGRDIDP SNHYSLQRYPGIFNSTTSDAFLQSKMRNIFSGRLTAVELVDILDHYTKNCDMMVGNQALIQGLK KEKFDLLLVDPNDMCGFVIAHLLGVKYAVFSTGLWYPAEVGAPAPLAYVPEFNSLLTDRMNFLE RMKNTGVYLISRMGVSFLVLPKYERIMQKYNLLPAKSMYDLVHGSSLWMLCTDVALEFPRPTLP NVVYVGGILTKPASPLPEDLQRWVDGAQEHGFVLVSFGAGVKYLSEDIANKLAGALGRLPQKVI WRFSGTKPKNLGNNTKLIEWLPQNDLLGHSNIRAFLSHGGLNSIFETMYHGVPVVGIPLFGDHY DTMTRVQAKGMGILLEWNTVTEGELYDALVKVINNPSYRQRAQKLSEIHKDQPGHPVNRTTYWI DYILRHDGAHHLRSAVHQISFCQYFLLDIAFVLLLGAVALYFIVSYVTKFIYRKVKSLCSRSTH STVNGHYQNGILNGRYKGNGHIKHEKKVK hide sequence

RefSeq Acc Id:

ENSRNOP00000012676 ⟸ ENSRNOT00000012676

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691736

Promoter ID:

EPDNEW_R2261

Type:

single initiation site

Name:

Ugt8_1

Description:

UDP glycosyltransferase 8

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	229,718,746 - 229,718,806	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3938	AgrOrtholog
Ensembl Genes	ENSRNOG00000009345	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000012676	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000012676	ENTREZGENE, UniProtKB/Swiss-Prot
InterPro	UDP_glucos_trans	UniProtKB/Swiss-Prot
	UDP_glycos_trans_CS	UniProtKB/Swiss-Prot
KEGG Report	rno:50555	UniProtKB/Swiss-Prot
NCBI Gene	50555	ENTREZGENE
Pfam	UDPGT	UniProtKB/Swiss-Prot
PhenoGen	Ugt8	PhenoGen
PROSITE	UDPGT	UniProtKB/Swiss-Prot
UniProt	CGT_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-08-29	Ugt8	UDP glycosyltransferase 8	Ugt8a	UDP galactosyltransferase 8A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-15	Ugt8a	UDP galactosyltransferase 8A	Ugt8	UDP galactosyltransferase 8	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-11-17	Ugt8	UDP galactosyltransferase 8			Name updated	1299863	APPROVED
2002-06-10	Ugt8	UDP-glucuronosyltransferase 8			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	developmental expression of mRNA similar to the myelination profile	70050
gene_protein	predicted protein masses 61 kDa	70050
gene_transcript	open reading frame of 1623 bp	70050

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)