Mocs2 (molybdenum cofactor synthesis 2) - Rat Genome Database

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Gene: Mocs2 (molybdenum cofactor synthesis 2) Rattus norvegicus
Analyze
Symbol: Mocs2
Name: molybdenum cofactor synthesis 2
RGD ID: 1359477
Description: Predicted to enable identical protein binding activity. Predicted to contribute to molybdopterin synthase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process. Predicted to be located in nuclear speck. Predicted to be part of molybdopterin synthase complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type B. Orthologous to human MOCS2 (molybdenum cofactor synthesis 2); PARTICIPATES IN molybdenum cofactor biosynthetic pathway; folate metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC94220; MOCS2B; molybdenum cofactor synthesis protein 2 large subunit; molybdenum cofactor synthesis protein 2B; molybdopterin synthase; molybdopterin synthase catalytic subunit; molybdopterin synthase sulfur carrier subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2246,504,574 - 46,516,327 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl246,504,588 - 46,516,324 (+)Ensembl
Rnor_6.0246,980,964 - 46,992,886 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl246,980,976 - 46,992,883 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0271,520,174 - 71,532,084 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4246,948,321 - 46,960,060 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1246,876,587 - 46,888,290 (+)NCBI
Celera242,260,839 - 42,272,490 (+)NCBICelera
Cytogenetic Map2q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:11591653   PMID:12732628   PMID:15073332   PMID:23376485  


Genomics

Comparative Map Data
Mocs2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2246,504,574 - 46,516,327 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl246,504,588 - 46,516,324 (+)Ensembl
Rnor_6.0246,980,964 - 46,992,886 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl246,980,976 - 46,992,883 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0271,520,174 - 71,532,084 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4246,948,321 - 46,960,060 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1246,876,587 - 46,888,290 (+)NCBI
Celera242,260,839 - 42,272,490 (+)NCBICelera
Cytogenetic Map2q14NCBI
MOCS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38553,095,679 - 53,109,757 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl553,095,679 - 53,110,063 (-)EnsemblGRCh38hg38GRCh38
GRCh37552,391,509 - 52,405,587 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36552,429,649 - 52,441,355 (-)NCBINCBI36hg18NCBI36
Build 34552,429,653 - 52,441,355NCBI
Celera549,347,470 - 49,359,176 (-)NCBI
Cytogenetic Map5q11.2NCBI
HuRef549,363,558 - 49,377,653 (-)NCBIHuRef
CHM1_1552,394,058 - 52,408,152 (-)NCBICHM1_1
Mocs2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913114,954,707 - 114,965,956 (+)NCBIGRCm39mm39
GRCm39 Ensembl13114,954,772 - 114,968,811 (+)Ensembl
GRCm3813114,818,160 - 114,829,420 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13114,818,236 - 114,832,275 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713115,608,445 - 115,619,628 (+)NCBIGRCm37mm9NCBIm37
MGSCv3613115,939,164 - 115,949,607 (+)NCBImm8
Celera13119,161,937 - 119,173,119 (+)NCBICelera
Cytogenetic Map13D2.2NCBI
Mocs2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544614,295,737 - 14,307,838 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544614,295,737 - 14,305,735 (+)NCBIChiLan1.0ChiLan1.0
MOCS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1562,539,208 - 62,550,926 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl562,539,214 - 62,550,921 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0560,920,268 - 60,931,990 (+)NCBIMhudiblu_PPA_v0panPan3
MOCS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1462,153,828 - 62,164,154 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl462,153,296 - 62,185,492 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha461,928,792 - 61,939,117 (+)NCBI
ROS_Cfam_1.0462,651,866 - 62,662,174 (+)NCBI
UMICH_Zoey_3.1462,427,116 - 62,437,429 (+)NCBI
UNSW_CanFamBas_1.0462,551,658 - 62,561,990 (+)NCBI
UU_Cfam_GSD_1.0463,078,354 - 63,088,687 (+)NCBI
Mocs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213205,369,033 - 205,380,226 (+)NCBI
SpeTri2.0NW_00493648014,302,824 - 14,313,265 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MOCS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1632,424,645 - 32,462,521 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11632,427,783 - 32,462,362 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21634,270,548 - 34,290,713 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MOCS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1449,387,923 - 49,399,902 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl449,386,487 - 49,399,928 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660821,727,742 - 1,739,745 (+)NCBIVero_WHO_p1.0
Mocs2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247596,261,970 - 6,272,246 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D5Wox6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2246,509,113 - 46,509,732 (+)MAPPERmRatBN7.2
Rnor_6.0246,985,503 - 46,986,121NCBIRnor6.0
Rnor_5.0271,524,701 - 71,525,319UniSTSRnor5.0
RGSC_v3.4246,952,847 - 46,953,465UniSTSRGSC3.4
Celera242,265,277 - 42,265,895UniSTS
Cytogenetic Map2q14UniSTS
RH133558  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2246,515,655 - 46,515,860 (+)MAPPERmRatBN7.2
Rnor_6.0246,992,215 - 46,992,419NCBIRnor6.0
Rnor_5.0271,531,413 - 71,531,617UniSTSRnor5.0
RGSC_v3.4246,959,389 - 46,959,593UniSTSRGSC3.4
Celera242,271,819 - 42,272,023UniSTS
RH 3.4 Map2304.4UniSTS
Cytogenetic Map2q14UniSTS
BF404043  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2246,508,124 - 46,508,318 (+)MAPPERmRatBN7.2
Rnor_6.0246,984,514 - 46,984,707NCBIRnor6.0
Rnor_5.0271,523,712 - 71,523,905UniSTSRnor5.0
RGSC_v3.4246,951,858 - 46,952,051UniSTSRGSC3.4
Celera242,264,288 - 42,264,481UniSTS
RH 3.4 Map2292.3UniSTS
Cytogenetic Map2q14UniSTS
AW535104  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2246,508,195 - 46,508,347 (+)MAPPERmRatBN7.2
Rnor_6.0246,984,585 - 46,984,736NCBIRnor6.0
Rnor_5.0271,523,783 - 71,523,934UniSTSRnor5.0
RGSC_v3.4246,951,929 - 46,952,080UniSTSRGSC3.4
Celera242,264,359 - 42,264,510UniSTS
RH 3.4 Map2294.8UniSTS
Cytogenetic Map2q14UniSTS
RH139819  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2246,516,084 - 46,516,277 (+)MAPPERmRatBN7.2
Rnor_6.0246,992,644 - 46,992,836NCBIRnor6.0
Rnor_5.0271,531,842 - 71,532,034UniSTSRnor5.0
RGSC_v3.4246,959,818 - 46,960,010UniSTSRGSC3.4
Celera242,272,248 - 42,272,440UniSTS
Cytogenetic Map2q14UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
738012Anxrr3Anxiety related response QTL 33.8exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)2902351954023519Rat
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21159110056591100Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)21185206249003364Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22490385374786777Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
1643006Pain1Pain QTL 13.630.005mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)22699957148268661Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22715716072157160Rat
1300160Hrtrt3Heart rate QTL 33.62heart pumping trait (VT:2000009)absolute change in heart rate (CMO:0000534)22997159351729300Rat
10755434Coatc7Coat color QTL 70.04794coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23064806575648065Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23502311780023117Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23513484188029593Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)240067944102785628Rat
12879863Bp402Blood pressure QTL 4020.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24112578956532139Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)24280460760653831Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
2293676Bmd19Bone mineral density QTL 1910.70.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)243162366111362592Rat
2293682Bmd24Bone mineral density QTL 248.90.0001femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)243162366111362592Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24317101783575226Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:165
Count of miRNA genes:126
Interacting mature miRNAs:138
Transcripts:ENSRNOT00000015781
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 36 11 8
Low 5
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001007633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001162413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001395667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001395668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001395669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006231985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006231986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC079181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO554692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM123325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000082990   ⟹   ENSRNOP00000073722
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl246,504,588 - 46,516,324 (+)Ensembl
Rnor_6.0 Ensembl246,981,010 - 46,992,883 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083668   ⟹   ENSRNOP00000069073
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl246,980,976 - 46,992,883 (+)Ensembl
RefSeq Acc Id: NM_001007633   ⟹   NP_001007634
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2246,504,588 - 46,516,327 (+)NCBI
Rnor_6.0246,980,976 - 46,992,886 (+)NCBI
Rnor_5.0271,520,174 - 71,532,084 (+)NCBI
RGSC_v3.4246,948,321 - 46,960,060 (+)RGD
Celera242,260,839 - 42,272,490 (+)RGD
Sequence:
RefSeq Acc Id: NM_001162413   ⟹   NP_001155885
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2246,504,588 - 46,516,327 (+)NCBI
Rnor_6.0246,980,976 - 46,992,886 (+)NCBI
Rnor_5.0271,520,174 - 71,532,084 (+)NCBI
RGSC_v3.4246,948,321 - 46,960,060 (+)RGD
Celera242,260,839 - 42,272,490 (+)RGD
Sequence:
RefSeq Acc Id: XM_006231985   ⟹   XP_006232047
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2246,504,608 - 46,516,327 (+)NCBI
Rnor_6.0246,981,010 - 46,992,886 (+)NCBI
Rnor_5.0271,520,174 - 71,532,084 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006231986   ⟹   XP_006232048
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2246,504,574 - 46,516,327 (+)NCBI
Rnor_6.0246,980,986 - 46,992,886 (+)NCBI
Rnor_5.0271,520,174 - 71,532,084 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001007634   ⟸   NM_001007633
- Peptide Label: isoform Mocs2B
- UniProtKB: Q6AY59 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001155885   ⟸   NM_001162413
- Peptide Label: isoform Mocs2A
- UniProtKB: Q6AY59 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006232048   ⟸   XM_006231986
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006232047   ⟸   XM_006231985
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000073722   ⟸   ENSRNOT00000082990
RefSeq Acc Id: ENSRNOP00000069073   ⟸   ENSRNOT00000083668

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691147
Promoter ID:EPDNEW_R1672
Type:initiation region
Name:Mocs2_1
Description:molybdenum cofactor synthesis 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0246,981,009 - 46,981,069EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
2 46983738 46983739 C A snv ACI/EurMcwi (MCW), ACI/N (MCW), ACI/EurMcwi (2019), ACI/N (2020), ACI/EurMcwi (RGD)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359477 AgrOrtholog
BioCyc Gene G2FUF-54327 BioCyc
BioCyc Pathway PWY-6823 [molybdopterin biosynthesis] BioCyc
Ensembl Genes ENSRNOG00000056325 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000069073 UniProtKB/Swiss-Prot
  ENSRNOP00000073722 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000082990 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000083668 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.1170.40 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7130858 IMAGE-MGC_LOAD
InterPro MoaE_sf UniProtKB/Swiss-Prot
  MOCS2B_euk UniProtKB/Swiss-Prot
  Mopterin_biosynth_MoaE UniProtKB/Swiss-Prot
KEGG Report rno:294753 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94220 IMAGE-MGC_LOAD
NCBI Gene 294753 ENTREZGENE
Pfam MoaE UniProtKB/Swiss-Prot
PhenoGen Mocs2 PhenoGen
Superfamily-SCOP SSF54690 UniProtKB/Swiss-Prot
UniProt MOC2B_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Mocs2  molybdenum cofactor synthesis 2    molybdopterin synthase  Name updated 1299863 APPROVED
2005-07-29 Mocs2  molybdopterin synthase      Symbol and Name status set to provisional 70820 PROVISIONAL