Mocs2 (molybdenum cofactor synthesis 2)

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Gene: Mocs2 (molybdenum cofactor synthesis 2) Rattus norvegicus

Analyze

Symbol:

Mocs2

Name:

molybdenum cofactor synthesis 2

RGD ID:

1359477

Description:

Predicted to enable identical protein binding activity. Predicted to contribute to molybdopterin synthase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process. Predicted to be located in nuclear speck. Predicted to be part of molybdopterin synthase complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type B. Orthologous to human MOCS2 (molybdenum cofactor synthesis 2); PARTICIPATES IN molybdenum cofactor biosynthetic pathway; folate metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

MGC94220; MOCS2B; molybdenum cofactor synthesis protein 2 large subunit; molybdenum cofactor synthesis protein 2B; molybdopterin synthase; molybdopterin synthase catalytic subunit; molybdopterin synthase sulfur carrier subunit

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MOCS2 (molybdenum cofactor synthesis 2)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):	Mocs2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mocs2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MOCS2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MOCS2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mocs2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MOCS2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MOCS2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mocs2 (molybdenum cofactor synthesis 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	MOCS2 (molybdenum cofactor synthesis 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Mocs2 (molybdenum cofactor synthesis 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nmrk-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Mocs2B	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	46,504,574 - 46,516,327 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	46,504,588 - 46,516,324 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	53,614,202 - 53,625,948 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	2	51,672,578 - 51,684,324 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	2	46,540,417 - 46,552,139 (+)	NCBI	Rnor_WKY
Rnor_6.0	2	46,980,964 - 46,992,886 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	46,980,976 - 46,992,883 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	71,520,174 - 71,532,084 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	46,948,321 - 46,960,060 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	46,876,587 - 46,888,290 (+)	NCBI
Celera	2	42,260,839 - 42,272,490 (+)	NCBI		Celera
Cytogenetic Map	2	q14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

inherited metabolic disorder (ISO,ISS)

molybdenum cofactor deficiency (ISO)

molybdenum cofactor deficiency type A (ISO)

molybdenum cofactor deficiency type B (ISO)

Neurodevelopmental Disorders (ISO)

platelet-type bleeding disorder 9 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,1,1-trichloroethane (ISO)

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

azoxystrobin (EXP)

benzo[a]pyrene (ISO)

Benzo[k]fluoranthene (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

chlordecone (ISO)

chlorpyrifos (EXP)

cisplatin (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dibutyl phthalate (EXP)

doxorubicin (ISO)

flutamide (EXP)

folic acid (ISO)

glyphosate (EXP)

hydrogen peroxide (ISO)

imidacloprid (EXP)

methylmercury chloride (ISO)

Muraglitazar (EXP)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

nefazodone (EXP)

nimesulide (EXP)

paracetamol (ISO)

quercetin (ISO)

rotenone (EXP)

silicon dioxide (ISO)

sodium arsenite (ISO)

Tesaglitazar (EXP)

tetrachloromethane (EXP)

thiabendazole (EXP)

trichostatin A (ISO)

triphenyl phosphate (EXP)

triptonide (ISO)

troglitazone (EXP)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

Mo-molybdopterin cofactor biosynthetic process (ISO,ISS)

Cellular Component

cellular_component (ND)

cytosol (IBA,ISO)

cytosol (ISO)

cytosol (ISS)

molybdopterin synthase complex (ISO)

nuclear speck (IEA,ISO)

nucleoplasm (ISO)

Molecular Function

identical protein binding (ISO)

molecular_function (ND)

molybdopterin synthase activity (ISO,ISS)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

folate metabolic pathway (IEA)

molybdenum cofactor biosynthetic pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Cell biology of molybdenum.	Mendel RR and Bittner F, Biochim Biophys Acta. 2006 Jul;1763(7):621-35. Epub 2006 May 12.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	Mutations in the molybdenum cofactor biosynthetic genes MOCS1, MOCS2, and GEPH.	Reiss J and Johnson JL, Hum Mutat 2003 Jun;21(6):569-76.
8.	Human molybdopterin synthase gene: genomic structure and mutations in molybdenum cofactor deficiency type B.	Reiss J, etal., Am J Hum Genet 1999 Mar;64(3):706-11.
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Comprehensive gene review and curation	RGD comprehensive gene curation
13.	The two subunits of human molybdopterin synthase: evidence for a bicistronic messenger RNA with overlapping reading frames.	Sloan J, etal., Nucleic Acids Res 1999 Feb 1;27(3):854-8.
14.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11591653	PMID:12732628	PMID:15073332	PMID:23376485

Genomics

Comparative Map Data

Mocs2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	46,504,574 - 46,516,327 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	46,504,588 - 46,516,324 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	53,614,202 - 53,625,948 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	2	51,672,578 - 51,684,324 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	2	46,540,417 - 46,552,139 (+)	NCBI	Rnor_WKY
Rnor_6.0	2	46,980,964 - 46,992,886 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	46,980,976 - 46,992,883 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	71,520,174 - 71,532,084 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	46,948,321 - 46,960,060 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	46,876,587 - 46,888,290 (+)	NCBI
Celera	2	42,260,839 - 42,272,490 (+)	NCBI		Celera
Cytogenetic Map	2	q14	NCBI

MOCS2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	53,095,679 - 53,109,757 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	5	53,095,679 - 53,110,063 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	52,391,509 - 52,405,587 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	52,429,649 - 52,441,355 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	52,429,653 - 52,441,355	NCBI
Celera	5	49,347,470 - 49,359,176 (-)	NCBI		Celera
Cytogenetic Map	5	q11.2	NCBI
HuRef	5	49,363,558 - 49,377,653 (-)	NCBI		HuRef
CHM1_1	5	52,394,058 - 52,408,152 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	53,923,465 - 53,937,543 (-)	NCBI		T2T-CHM13v2.0

Mocs2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	114,954,707 - 114,965,956 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	114,954,772 - 114,968,811 (+)	Ensembl		GRCm39 Ensembl
GRCm38	13	114,818,160 - 114,829,420 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	114,818,236 - 114,832,275 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	115,608,445 - 115,619,628 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	115,939,164 - 115,949,607 (+)	NCBI		MGSCv36	mm8
Celera	13	119,161,937 - 119,173,119 (+)	NCBI		Celera
Cytogenetic Map	13	D2.2	NCBI

Mocs2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955446	14,295,737 - 14,307,838 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955446	14,295,737 - 14,305,735 (+)	NCBI	ChiLan1.0	ChiLan1.0

MOCS2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	5	62,539,208 - 62,550,926 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	62,539,214 - 62,550,921 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	5	60,920,268 - 60,931,990 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

MOCS2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	62,153,828 - 62,164,154 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	62,153,296 - 62,185,492 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	61,928,792 - 61,939,117 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	62,651,866 - 62,662,174 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	4	62,427,116 - 62,437,429 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	62,551,658 - 62,561,990 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	63,078,354 - 63,088,687 (+)	NCBI		UU_Cfam_GSD_1.0

Mocs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	205,369,033 - 205,380,226 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936480	14,302,824 - 14,313,265 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MOCS2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	32,436,205 - 32,462,521 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	32,427,783 - 32,462,362 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	34,270,548 - 34,290,713 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MOCS2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	49,387,923 - 49,399,902 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	49,386,487 - 49,399,928 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666082	1,727,742 - 1,739,745 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mocs2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624759	6,261,933 - 6,271,509 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624759	6,261,970 - 6,272,246 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mocs2
123 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	165
Count of miRNA genes:	126
Interacting mature miRNAs:	138
Transcripts:	ENSRNOT00000015781
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	5873687	102844969	Rat
738012	Anxrr3	Anxiety related response QTL 3	3.8		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	2	9023519	54023519	Rat
10755430	Coatc6	Coat color QTL 6		0.02576	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	11591100	56591100	Rat
1578664	Bmd9	Bone mineral QTL density 9	5		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	11852062	49003364	Rat
731184	Mamtr4	Mammary tumor resistance QTL 4		0.0003	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	16491740	61491740	Rat
1357990	Ael1	Aortic elastin QTL 1	3.1	0.00091	aorta elastin amount (VT:0003905)	aortic elastin	2	19076825	64076825	Rat
731167	Glom4	Glomerulus QTL 4	2.4	0.0082	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	2	20304672	65304672	Rat
2300168	Bmd47	Bone mineral density QTL 47	6.6	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	2	20662448	65662448	Rat
10402051	Gdil2	Gastrointestinal dilation QTL 2			enteric ganglion morphology trait (VT:0001045)	length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)	2	24903853	74786777	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	25413423	143657569	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	26917817	81754745	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	26917817	81754745	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	81754745	Rat
1354603	Bp243	Blood pressure QTL 243	3.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	127469484	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	26917817	136917119	Rat
1643006	Pain1	Pain QTL 1	3.63	0.005	mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	2	26999571	48268661	Rat
9590095	Sffal3	Serum free fatty acids level QTL 3	6.78	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	2	27157160	72157160	Rat
1300160	Hrtrt3	Heart rate QTL 3	3.62		heart pumping trait (VT:2000009)	absolute change in heart rate (CMO:0000534)	2	29971593	51729300	Rat
10755434	Coatc7	Coat color QTL 7		0.04794	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	30648065	75648065	Rat
10755436	Coatc8	Coat color QTL 8		0.02431	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	35023117	80023117	Rat
61371	Edpm1	Estrogen-dependent pituitary mass QTL 1	4	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	35134841	88029593	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	40067944	102785628	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	40067944	102785628	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	40067944	102785628	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	2	40067944	102785628	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	40067944	102785628	Rat
12879863	Bp402	Blood pressure QTL 402		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	41125789	56532139	Rat
1300155	Bp174	Blood pressure QTL 174	4.09		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	42804607	60653831	Rat
2293835	Kiddil5	Kidney dilation QTL 5	3.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	42804607	157142209	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	42804607	182042367	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	43154682	202446871	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
2293676	Bmd19	Bone mineral density QTL 19	10.7	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	43162366	111362592	Rat
2293682	Bmd24	Bone mineral density QTL 24	8.9	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	2	43162366	111362592	Rat
2293671	Bss44	Bone structure and strength QTL 44	10.97	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	2	43162366	148478373	Rat
631208	Bw1	Body weight QTL1	5.09		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	2	43171017	83575226	Rat
1354601	Slep1	Serum leptin concentration QTL 1	5.39		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	2	43171017	184114403	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat

Markers in Region

D5Wox6

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	46,509,113 - 46,509,732 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	46,985,503 - 46,986,121	NCBI	Rnor6.0
Rnor_5.0	2	71,524,701 - 71,525,319	UniSTS	Rnor5.0
RGSC_v3.4	2	46,952,847 - 46,953,465	UniSTS	RGSC3.4
Celera	2	42,265,277 - 42,265,895	UniSTS
Cytogenetic Map	2	q14	UniSTS

RH133558

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	46,515,655 - 46,515,860 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	46,992,215 - 46,992,419	NCBI	Rnor6.0
Rnor_5.0	2	71,531,413 - 71,531,617	UniSTS	Rnor5.0
RGSC_v3.4	2	46,959,389 - 46,959,593	UniSTS	RGSC3.4
Celera	2	42,271,819 - 42,272,023	UniSTS
RH 3.4 Map	2	304.4	UniSTS
Cytogenetic Map	2	q14	UniSTS

BF404043

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	46,508,124 - 46,508,318 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	46,984,514 - 46,984,707	NCBI	Rnor6.0
Rnor_5.0	2	71,523,712 - 71,523,905	UniSTS	Rnor5.0
RGSC_v3.4	2	46,951,858 - 46,952,051	UniSTS	RGSC3.4
Celera	2	42,264,288 - 42,264,481	UniSTS
RH 3.4 Map	2	292.3	UniSTS
Cytogenetic Map	2	q14	UniSTS

AW535104

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	46,508,195 - 46,508,347 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	46,984,585 - 46,984,736	NCBI	Rnor6.0
Rnor_5.0	2	71,523,783 - 71,523,934	UniSTS	Rnor5.0
RGSC_v3.4	2	46,951,929 - 46,952,080	UniSTS	RGSC3.4
Celera	2	42,264,359 - 42,264,510	UniSTS
RH 3.4 Map	2	294.8	UniSTS
Cytogenetic Map	2	q14	UniSTS

RH139819

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	46,516,084 - 46,516,277 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	46,992,644 - 46,992,836	NCBI	Rnor6.0
Rnor_5.0	2	71,531,842 - 71,532,034	UniSTS	Rnor5.0
RGSC_v3.4	2	46,959,818 - 46,960,010	UniSTS	RGSC3.4
Celera	2	42,272,248 - 42,272,440	UniSTS
Cytogenetic Map	2	q14	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	36	11	8
Low											5
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001007633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001162413	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001395667	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001395668	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001395669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590714	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590715	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC079181	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO554692	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM123325	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220210	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ235152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000082990 ⟹ ENSRNOP00000073722

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	46,504,588 - 46,516,324 (+)	Ensembl
Rnor_6.0 Ensembl	2	46,981,010 - 46,992,883 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000083668 ⟹ ENSRNOP00000069073

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	2	46,980,976 - 46,992,883 (+)	Ensembl

RefSeq Acc Id:

NM_001007633 ⟹ NP_001007634

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	46,504,588 - 46,516,327 (+)	NCBI
Rnor_6.0	2	46,980,976 - 46,992,886 (+)	NCBI
Rnor_5.0	2	71,520,174 - 71,532,084 (+)	NCBI
RGSC_v3.4	2	46,948,321 - 46,960,060 (+)	RGD
Celera	2	42,260,839 - 42,272,490 (+)	RGD

Sequence:

show sequence

GTGGAGCATCCGGCTGCGCATGCGCCCTGAGTCACCGGCTCCGACGGGGTTGGTGAACTGGCTC
CCGGCAGTGTAGCGGGATGGTTCCTAGGTGTCAGGTTGGCTGATGTTAGAAACCAGGTGATATT
TGCTGTTCGTCAAGAGTATGTCGAGCTTGGAGATCAACAACTCCTGCTTCAGCCTGGAGACGAA
GTTGCCATCATCCCACCAATCAGTGGAGGATAGTGCGTCTGAGCCATCGGGGTATGAGGCGAAG
GACCCTCCACAGGATACCTTGAAAGATGTGGATGATGTGCTGGAGAAACCTAAGGACATAATAC
AGTTCACTGCCAAGAAGCTCTCAGTGGGGGAAGTGTCACAGCTGGTGGTGTCCCCTCTGTGTGG
CGCAGTGTCTCTCTTTGTAGGGACTACAAGAAATAACTTCGAAGGCAAGAAAGTCATTAGCTTA
GAATATGAAGCATATCTACCCATGGCAGAAAATGAAATCAGAAAAATTTGCAATGACATTCGAC
AGAAATGGCCAGTGAGGCACATAGCGGTGTTCCATCGGCTTGGTCTGGTTCCAGTGTCAGAAGC
AAGCACAGTTATTGCTGTGTCCTCAGCTCACAGAGCCGCGTCCCTTGAAGCCGTGAGCTACGCC
ATTGATTCTTTAAAAGCCAAGGTGCCCATATGGAAGAAGGAAATATATGAAGAATCAACATCAT
CTTGGAAAAGAAACAAGGAATGCTTCTGGGCAGCTGATGACTAGTCAAGTTTTGGTGCACTGAA
TCTTAAATTTGGTAAATAATCGCTTAGGTTACACCAATGGAGAGCTAGGGAAGTGCCCAAGTGT
GTGGGATGAGGAGCTGCGTAGGACCTAAAGCTGGGAAGACATGGCTTAACTTGAACCTTCTGTG
ACTAACTCCTAGTCGTAGCCAGCTCACAACGAGCTGCAGCCTTCCTTTCACCATCAGCTGTCCC
AGGAAGACCTACTGTCCCACAGGGTATTGACGCATCGTGATAAGACATGTGTTACAAAAAATTG
ACGGAATCAGAAAATCATTCTCAGTTGTGACATTACATATTTTACATAACTTAGAAGTGAACCT
AAATAAATCATGATTTAAATTAAAAATAGATTCTGTTTCTCTTTTAGTCAGTGATAATACCTAA
GGGGTTTTACATTACAGACACCTCTCTGACTTCAGAATCCATAATTACACACAGTAAGGCTTTT
TTTATATCTCATTGGTTGTCAATATTCTCATCACTGTACAGATTAGCATAAAACTGTTCTAAAA
CTAACCAGCAGCAAGGTGGTTTATGTTAAAATGATGTATGATGCTTAAAAGTTGGCCCACAACT
ATTTGAGGACACTGTGTAATTATTTACTAAAGTAGTTTGGATAGTTTTCATAATGTTTATGTAA
CACTGGCCTGTGTGAAATTATTACTAAACAAATTAAATTTTCTGCAAGATTTTTATACCAAAAA
AAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001162413 ⟹ NP_001155885

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	46,504,588 - 46,516,327 (+)	NCBI
Rnor_6.0	2	46,980,976 - 46,992,886 (+)	NCBI
Rnor_5.0	2	71,520,174 - 71,532,084 (+)	NCBI
RGSC_v3.4	2	46,948,321 - 46,960,060 (+)	RGD
Celera	2	42,260,839 - 42,272,490 (+)	RGD

Sequence:

show sequence

GTGGAGCATCCGGCTGCGCATGCGCCCTGAGTCACCGGCTCCGACGGGGTTGGTGAACTGGCTC
CCGGCAGTGTAGCGGGATGGTTCCTAGGTGTCAGATCGAAGTGTTGTATTTTGCAAAAAGTGCT
GAAATCGCTGGCGTTCGCTCCGAGACCATCTCTGTGCCACAGGAAATCAAGGCATCACAGCTGT
GGCAGGAGCTAGAGACTCTCCATCCTGGGTTGGCTGATGTTAGAAACCAGGTGATATTTGCTGT
TCGTCAAGAGTATGTCGAGCTTGGAGATCAACAACTCCTGCTTCAGCCTGGAGACGAAGTTGCC
ATCATCCCACCAATCAGTGGAGGATAGTGCGTCTGAGCCATCGGGGTATGAGGCGAAGGACCCT
CCACAGGATACCTTGAAAGATGTGGATGATGTGCTGGAGAAACCTAAGGACATAATACAGTTCA
CTGCCAAGAAGCTCTCAGTGGGGGAAGTGTCACAGCTGGTGGTGTCCCCTCTGTGTGGCGCAGT
GTCTCTCTTTGTAGGGACTACAAGAAATAACTTCGAAGGCAAGAAAGTCATTAGCTTAGAATAT
GAAGCATATCTACCCATGGCAGAAAATGAAATCAGAAAAATTTGCAATGACATTCGACAGAAAT
GGCCAGTGAGGCACATAGCGGTGTTCCATCGGCTTGGTCTGGTTCCAGTGTCAGAAGCAAGCAC
AGTTATTGCTGTGTCCTCAGCTCACAGAGCCGCGTCCCTTGAAGCCGTGAGCTACGCCATTGAT
TCTTTAAAAGCCAAGGTGCCCATATGGAAGAAGGAAATATATGAAGAATCAACATCATCTTGGA
AAAGAAACAAGGAATGCTTCTGGGCAGCTGATGACTAGTCAAGTTTTGGTGCACTGAATCTTAA
ATTTGGTAAATAATCGCTTAGGTTACACCAATGGAGAGCTAGGGAAGTGCCCAAGTGTGTGGGA
TGAGGAGCTGCGTAGGACCTAAAGCTGGGAAGACATGGCTTAACTTGAACCTTCTGTGACTAAC
TCCTAGTCGTAGCCAGCTCACAACGAGCTGCAGCCTTCCTTTCACCATCAGCTGTCCCAGGAAG
ACCTACTGTCCCACAGGGTATTGACGCATCGTGATAAGACATGTGTTACAAAAAATTGACGGAA
TCAGAAAATCATTCTCAGTTGTGACATTACATATTTTACATAACTTAGAAGTGAACCTAAATAA
ATCATGATTTAAATTAAAAATAGATTCTGTTTCTCTTTTAGTCAGTGATAATACCTAAGGGGTT
TTACATTACAGACACCTCTCTGACTTCAGAATCCATAATTACACACAGTAAGGCTTTTTTTATA
TCTCATTGGTTGTCAATATTCTCATCACTGTACAGATTAGCATAAAACTGTTCTAAAACTAACC
AGCAGCAAGGTGGTTTATGTTAAAATGATGTATGATGCTTAAAAGTTGGCCCACAACTATTTGA
GGACACTGTGTAATTATTTACTAAAGTAGTTTGGATAGTTTTCATAATGTTTATGTAACACTGG
CCTGTGTGAAATTATTACTAAACAAATTAAATTTTCTGCAAGATTTTTATACCAAAAAAAAAAA
AAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006231985 ⟹ XP_006232047

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	46,504,608 - 46,516,327 (+)	NCBI
Rnor_6.0	2	46,981,010 - 46,992,886 (+)	NCBI
Rnor_5.0	2	71,520,174 - 71,532,084 (+)	NCBI

Sequence:

show sequence

CCGGCTCCGACGGGGTTGGTGAACTGGCTCCCGGCAGTGTAGCGGGATGGTTCCTAGGTGTCAG
ATCGAAGTGTTGTATTTTGCAAAAAGTGCTGAAATCGCTGGCGTTCGCTCCGAGACCATCTCTG
TGCCACAGGAAATCAAGGCATCACAGCTGTGGCAGGAGCTAGAGACTCTCCATCCTGGGTTGGC
TGATGTTAGAAACCAGGTGATATTTGCTGTTCGTCAAGAGTATGTCGAGCTTGGAGATCAACAA
CTCCTGCTTCAGCCTGGAGACGAAGTTGCCATCATCCCACCAATCAGTGGAGGATAGTGCGTCT
GAGCCATCGGGGAAAGATGTGGATGATGTGCTGGAGAAACCTAAGGACATAATACAGTTCACTG
CCAAGAAGCTCTCAGTGGGGGAAGTGTCACAGCTGGTGGTGTCCCCTCTGTGTGGCGCAGTGTC
TCTCTTTGTAGGGACTACAAGAAATAACTTCGAAGGCAAGAAAGTCATTAGCTTAGAATATGAA
GCATATCTACCCATGGCAGAAAATGAAATCAGAAAAATTTGCAATGACATTCGACAGAAATGGC
CAGTGAGGCACATAGCGGTGTTCCATCGGCTTGGTCTGGTTCCAGTGTCAGAAGCAAGCACAGT
TATTGCTGTGTCCTCAGCTCACAGAGCCGCGTCCCTTGAAGCCGTGAGCTACGCCATTGATTCT
TTAAAAGCCAAGGTGCCCATATGGAAGAAGGAAATATATGAAGAATCAACATCATCTTGGAAAA
GAAACAAGGAATGCTTCTGGGCAGCTGATGACTAGTCAAGTTTTGGTGCACTGAATCTTAAATT
TGGTAAATAATCGCTTAGGTTACACCAATGGAGAGCTAGGGAAGTGCCCAAGTGTGTGGGATGA
GGAGCTGCGTAGGACCTAAAGCTGGGAAGACATGGCTTAACTTGAACCTTCTGTGACTAACTCC
TAGTCGTAGCCAGCTCACAACGAGCTGCAGCCTTCCTTTCACCATCAGCTGTCCCAGGAAGACC
TACTGTCCCACAGGGTATTGACGCATCGTGATAAGACATGTGTTACAAAAAATTGACGGAATCA
GAAAATCATTCTCAGTTGTGACATTACATATTTTACATAACTTAGAAGTGAACCTAAATAAATC
ATGATTTAAATTAAAAATAGATTCTGTTTCTCTTTTAGTCAGTGATAATACCTAAGGGGTTTTA
CATTACAGACACCTCTCTGACTTCAGAATCCATAATTACACACAGTAAGGCTTTTTTTATATCT
CATTGGTTGTCAATATTCTCATCACTGTACAGATTAGCATAAAACTGTTCTAAAACTAACCAGC
AGCAAGGTGGTTTATGTTAAAATGATGTATGATGCTTAAAAGTTGGCCCACAACTATTTGAGGA
CACTGTGTAATTATTTACTAAAGTAGTTTGGATAGTTTTCATAATGTTTATGTAACACTGGCCT
GTGTGAAATTATTACTAAACAAATTAAATTTTCTGCAAGATTTTTATACCAAA

hide sequence

RefSeq Acc Id:

XM_006231986 ⟹ XP_006232048

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	46,504,574 - 46,516,327 (+)	NCBI
Rnor_6.0	2	46,980,986 - 46,992,886 (+)	NCBI
Rnor_5.0	2	71,520,174 - 71,532,084 (+)	NCBI

Sequence:

show sequence

CGGCTGCGCATGCGCCCTGAGTCACCGGCTCCGACGGGGTTGGTGAACTGGCTCCCGGCAGTGT
AGCGGGATGGTTCCTAGGTGTCAGGTTGGCTGATGTTAGAAACCAGGTGATATTTGCTGTTCGT
CAAGAGTATGTCGAGCTTGGAGATCAACAACTCCTGCTTCAGCCTGGAGACGAAGTTGCCATCA
TCCCACCAATCAGTGGAGGATAGTGCGTCTGAGCCATCGGGGAAAGATGTGGATGATGTGCTGG
AGAAACCTAAGGACATAATACAGTTCACTGCCAAGAAGCTCTCAGTGGGGGAAGTGTCACAGCT
GGTGGTGTCCCCTCTGTGTGGCGCAGTGTCTCTCTTTGTAGGGACTACAAGAAATAACTTCGAA
GGCAAGAAAGTCATTAGCTTAGAATATGAAGCATATCTACCCATGGCAGAAAATGAAATCAGAA
AAATTTGCAATGACATTCGACAGAAATGGCCAGTGAGGCACATAGCGGTGTTCCATCGGCTTGG
TCTGGTTCCAGTGTCAGAAGCAAGCACAGTTATTGCTGTGTCCTCAGCTCACAGAGCCGCGTCC
CTTGAAGCCGTGAGCTACGCCATTGATTCTTTAAAAGCCAAGGTGCCCATATGGAAGAAGGAAA
TATATGAAGAATCAACATCATCTTGGAAAAGAAACAAGGAATGCTTCTGGGCAGCTGATGACTA
GTCAAGTTTTGGTGCACTGAATCTTAAATTTGGTAAATAATCGCTTAGGTTACACCAATGGAGA
GCTAGGGAAGTGCCCAAGTGTGTGGGATGAGGAGCTGCGTAGGACCTAAAGCTGGGAAGACATG
GCTTAACTTGAACCTTCTGTGACTAACTCCTAGTCGTAGCCAGCTCACAACGAGCTGCAGCCTT
CCTTTCACCATCAGCTGTCCCAGGAAGACCTACTGTCCCACAGGGTATTGACGCATCGTGATAA
GACATGTGTTACAAAAAATTGACGGAATCAGAAAATCATTCTCAGTTGTGACATTACATATTTT
ACATAACTTAGAAGTGAACCTAAATAAATCATGATTTAAATTAAAAATAGATTCTGTTTCTCTT
TTAGTCAGTGATAATACCTAAGGGGTTTTACATTACAGACACCTCTCTGACTTCAGAATCCATA
ATTACACACAGTAAGGCTTTTTTTATATCTCATTGGTTGTCAATATTCTCATCACTGTACAGAT
TAGCATAAAACTGTTCTAAAACTAACCAGCAGCAAGGTGGTTTATGTTAAAATGATGTATGATG
CTTAAAAGTTGGCCCACAACTATTTGAGGACACTGTGTAATTATTTACTAAAGTAGTTTGGATA
GTTTTCATAATGTTTATGTAACACTGGCCTGTGTGAAATTATTACTAAACAAATTAAATTTTCT
GCAAGATTTTTATACCAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001007634	(Get FASTA)	NCBI Sequence Viewer
	NP_001155885	(Get FASTA)	NCBI Sequence Viewer
	NP_001382596	(Get FASTA)	NCBI Sequence Viewer
	NP_001382597	(Get FASTA)	NCBI Sequence Viewer
	NP_001382598	(Get FASTA)	NCBI Sequence Viewer
	XP_006232047	(Get FASTA)	NCBI Sequence Viewer
	XP_006232048	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79181	(Get FASTA)	NCBI Sequence Viewer
	EDM10385	(Get FASTA)	NCBI Sequence Viewer
	EDM10386	(Get FASTA)	NCBI Sequence Viewer
	EDM10387	(Get FASTA)	NCBI Sequence Viewer
	EDM10388	(Get FASTA)	NCBI Sequence Viewer
	EDM10389	(Get FASTA)	NCBI Sequence Viewer
	Q6AY59	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001007634 ⟸ NM_001007633
- Peptide Label:	isoform Mocs2B
- UniProtKB:	Q6AY59 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MSSLEINNSCFSLETKLPSSHQSVEDSASEPSGYEAKDPPQDTLKDVDDVLEKPKDIIQFTAKK LSVGEVSQLVVSPLCGAVSLFVGTTRNNFEGKKVISLEYEAYLPMAENEIRKICNDIRQKWPVR HIAVFHRLGLVPVSEASTVIAVSSAHRAASLEAVSYAIDSLKAKVPIWKKEIYEESTSSWKRNK ECFWAADD hide sequence

RefSeq Acc Id:	NP_001155885 ⟸ NM_001162413
- Peptide Label:	isoform Mocs2A
- UniProtKB:	Q6AY59 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MVPRCQIEVLYFAKSAEIAGVRSETISVPQEIKASQLWQELETLHPGLADVRNQVIFAVRQEYV ELGDQQLLLQPGDEVAIIPPISGG hide sequence

RefSeq Acc Id:	XP_006232048 ⟸ XM_006231986
- Peptide Label:	isoform X1
- Sequence:	show sequence MSSLEINNSCFSLETKLPSSHQSVEDSASEPSGKDVDDVLEKPKDIIQFTAKKLSVGEVSQLVV SPLCGAVSLFVGTTRNNFEGKKVISLEYEAYLPMAENEIRKICNDIRQKWPVRHIAVFHRLGLV PVSEASTVIAVSSAHRAASLEAVSYAIDSLKAKVPIWKKEIYEESTSSWKRNKECFWAADD hide sequence

RefSeq Acc Id:	XP_006232047 ⟸ XM_006231985
- Peptide Label:	isoform X1
- Sequence:	show sequence MSSLEINNSCFSLETKLPSSHQSVEDSASEPSGKDVDDVLEKPKDIIQFTAKKLSVGEVSQLVV SPLCGAVSLFVGTTRNNFEGKKVISLEYEAYLPMAENEIRKICNDIRQKWPVRHIAVFHRLGLV PVSEASTVIAVSSAHRAASLEAVSYAIDSLKAKVPIWKKEIYEESTSSWKRNKECFWAADD hide sequence

RefSeq Acc Id:

ENSRNOP00000073722 ⟸ ENSRNOT00000082990

RefSeq Acc Id:

ENSRNOP00000069073 ⟸ ENSRNOT00000083668

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AY59-F1-model_v2	AlphaFold	Q6AY59	1-200	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691147

Promoter ID:

EPDNEW_R1672

Type:

initiation region

Name:

Mocs2_1

Description:

molybdenum cofactor synthesis 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	46,981,009 - 46,981,069	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359477	AgrOrtholog
BioCyc Gene	G2FUF-54327	BioCyc
BioCyc Pathway	PWY-6823 [molybdopterin biosynthesis]	BioCyc
Ensembl Genes	ENSRNOG00000056325	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000073722	ENTREZGENE
	ENSRNOP00000073722.1	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000082990	ENTREZGENE
	ENSRNOT00000082990.2	UniProtKB/Swiss-Prot
Gene3D-CATH	3.90.1170.40	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7130858	IMAGE-MGC_LOAD
InterPro	MoaE_sf	UniProtKB/Swiss-Prot
	MOCS2B_euk	UniProtKB/Swiss-Prot
	Mopterin_biosynth_MoaE	UniProtKB/Swiss-Prot
KEGG Report	rno:294753	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94220	IMAGE-MGC_LOAD
NCBI Gene	294753	ENTREZGENE
PANTHER	MOLYBDOPTERIN SYNTHASE CATALYTIC SUBUNIT	UniProtKB/Swiss-Prot
	MOLYBDOPTERIN SYNTHASE RELATED	UniProtKB/Swiss-Prot
Pfam	MoaE	UniProtKB/Swiss-Prot
PhenoGen	Mocs2	PhenoGen
Superfamily-SCOP	SSF54690	UniProtKB/Swiss-Prot
UniProt	MOC2B_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Mocs2	molybdenum cofactor synthesis 2		molybdopterin synthase	Name updated	1299863	APPROVED
2005-07-29	Mocs2	molybdopterin synthase			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)