Hsf2bp (heat shock transcription factor 2 binding protein) - Rat Genome Database

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Gene: Hsf2bp (heat shock transcription factor 2 binding protein) Rattus norvegicus
Analyze
Symbol: Hsf2bp
Name: heat shock transcription factor 2 binding protein
RGD ID: 1565879
Description: Predicted to be involved in meiosis I and spermatogenesis. Predicted to be located in chromosome. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 19. Orthologous to human HSF2BP (heat shock transcription factor 2 binding protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: heat shock factor 2-binding protein; LOC499413; RGD1565879; similar to heat shock transcription factor 2 binding protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22010,035,562 - 10,123,059 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2010,035,562 - 10,121,242 (-)Ensembl
Rnor_6.02010,757,172 - 10,844,177 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2010,757,854 - 10,844,178 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02012,929,345 - 13,015,990 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42010,366,835 - 10,452,266 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2011,545,996 - 11,631,621 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromosome  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16780588  


Genomics

Comparative Map Data
Hsf2bp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22010,035,562 - 10,123,059 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2010,035,562 - 10,121,242 (-)Ensembl
Rnor_6.02010,757,172 - 10,844,177 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2010,757,854 - 10,844,178 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02012,929,345 - 13,015,990 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42010,366,835 - 10,452,266 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2011,545,996 - 11,631,621 (-)NCBICelera
Cytogenetic Map20p12NCBI
HSF2BP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382143,444,972 - 43,659,488 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2143,529,186 - 43,659,488 (-)EnsemblGRCh38hg38GRCh38
GRCh372144,949,066 - 45,079,369 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362143,773,500 - 43,903,802 (-)NCBINCBI36hg18NCBI36
Build 342143,773,500 - 43,903,802NCBI
Celera2130,055,601 - 30,185,204 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2130,317,613 - 30,447,221 (-)NCBIHuRef
CHM1_12144,510,276 - 44,640,115 (-)NCBICHM1_1
T2T-CHM13v2.02141,800,244 - 42,015,233 (-)NCBI
Hsf2bp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391732,163,743 - 32,253,869 (-)NCBIGRCm39mm39
GRCm39 Ensembl1732,163,743 - 32,255,323 (-)Ensembl
GRCm381731,944,769 - 32,034,895 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1731,944,769 - 32,036,349 (-)EnsemblGRCm38mm10GRCm38
MGSCv371732,081,714 - 32,171,453 (-)NCBIGRCm37mm9NCBIm37
MGSCv361731,673,479 - 31,763,609 (-)NCBImm8
Celera1732,861,327 - 32,951,080 (-)NCBICelera
Cytogenetic Map17B1NCBI
Hsf2bp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540738,577,789 - 38,671,929 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540738,577,463 - 38,671,929 (+)NCBIChiLan1.0ChiLan1.0
HSF2BP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12143,088,011 - 43,214,760 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2143,088,012 - 43,214,760 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02129,787,768 - 29,916,089 (-)NCBIMhudiblu_PPA_v0panPan3
HSF2BP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13137,543,448 - 37,643,534 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3137,503,052 - 37,643,505 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3136,697,994 - 36,799,702 (-)NCBI
ROS_Cfam_1.03137,086,703 - 37,186,586 (-)NCBI
ROS_Cfam_1.0 Ensembl3137,085,041 - 37,188,576 (-)Ensembl
UMICH_Zoey_3.13136,954,895 - 37,056,249 (-)NCBI
UNSW_CanFamBas_1.03136,939,941 - 37,041,634 (-)NCBI
UU_Cfam_GSD_1.03137,432,489 - 37,534,200 (-)NCBI
Hsf2bp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497136,791,828 - 36,867,636 (-)NCBI
SpeTri2.0NW_004936500600,628 - 676,201 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSF2BP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13206,545,354 - 206,629,156 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113206,545,353 - 206,629,151 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213216,653,123 - 216,696,922 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSF2BP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1287,262,882 - 87,434,217 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605415,375,114 - 15,500,819 (-)NCBIVero_WHO_p1.0
Hsf2bp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474527,388,239 - 27,462,569 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462474527,387,287 - 27,463,057 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D20Rat31  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22010,078,696 - 10,078,919 (+)MAPPERmRatBN7.2
Rnor_6.02010,800,308 - 10,800,530NCBIRnor6.0
Rnor_5.02012,972,481 - 12,972,703UniSTSRnor5.0
RGSC_v3.42010,410,005 - 10,410,227UniSTSRGSC3.4
RGSC_v3.42010,410,004 - 10,410,227RGDRGSC3.4
RGSC_v3.12010,410,232 - 10,410,454RGD
Celera2011,589,058 - 11,589,280UniSTS
RH 3.4 Map20152.9RGD
RH 3.4 Map20152.9UniSTS
RH 2.0 Map20147.9RGD
SHRSP x BN Map2011.54RGD
FHH x ACI Map204.6798RGD
Cytogenetic Map20p12UniSTS
D20Rat74  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22010,078,696 - 10,078,911 (+)MAPPERmRatBN7.2
Rnor_6.02010,800,308 - 10,800,522NCBIRnor6.0
Rnor_5.02012,972,481 - 12,972,695UniSTSRnor5.0
RGSC_v3.42010,410,004 - 10,410,219RGDRGSC3.4
RGSC_v3.42010,410,005 - 10,410,219UniSTSRGSC3.4
RGSC_v3.12010,410,232 - 10,410,446RGD
Celera2011,589,058 - 11,589,272UniSTS
RH 3.4 Map20151.0UniSTS
RH 3.4 Map20151.0RGD
RH 2.0 Map20147.9RGD
Cytogenetic Map20p12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat
4889857Pur27Proteinuria QTL 2712.20.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20460660717617956Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20669170617489458Rat
1581577Pur15Proteinuria QTL 154.380.0002total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)20804241017617956Rat
4889870Pur30Proteinuria QTL 30190.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804241029322208Rat
631265Iresp1Immunoglobin response QTL18.3blood anti-double stranded DNA antibody amount (VT:0004762)serum anti-DNA antibody level (CMO:0001533)20903971913461775Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:166
Count of miRNA genes:123
Interacting mature miRNAs:147
Transcripts:ENSRNOT00000001580
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 7
Low 26 14 8 14 8 1 1 28 32 33 5 1
Below cutoff 3 17 43 33 5 33 7 10 46 3 1 6 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000001580   ⟹   ENSRNOP00000001580
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2010,035,562 - 10,121,242 (-)Ensembl
Rnor_6.0 Ensembl2010,757,854 - 10,842,370 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079207   ⟹   ENSRNOP00000071827
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2010,037,500 - 10,121,242 (-)Ensembl
Rnor_6.0 Ensembl2010,758,367 - 10,844,178 (-)Ensembl
RefSeq Acc Id: NM_001127683   ⟹   NP_001121155
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22010,035,562 - 10,121,242 (-)NCBI
Rnor_6.02010,757,172 - 10,842,370 (-)NCBI
Rnor_5.02012,929,345 - 13,015,990 (-)NCBI
RGSC_v3.42010,366,835 - 10,452,266 (-)RGD
Celera2011,545,996 - 11,631,621 (-)RGD
Sequence:
RefSeq Acc Id: XM_017601757   ⟹   XP_017457246
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22010,036,856 - 10,123,059 (-)NCBI
Rnor_6.02010,758,466 - 10,844,177 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601758   ⟹   XP_017457247
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22010,036,856 - 10,123,059 (-)NCBI
Rnor_6.02010,758,466 - 10,843,219 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099002   ⟹   XP_038954930
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22010,069,640 - 10,121,514 (-)NCBI
RefSeq Acc Id: XM_039099004   ⟹   XP_038954932
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22010,037,362 - 10,121,507 (-)NCBI
RefSeq Acc Id: XR_005497325
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22010,036,856 - 10,121,511 (-)NCBI
RefSeq Acc Id: XR_005497326
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22010,073,006 - 10,121,511 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001121155   ⟸   NM_001127683
- UniProtKB: G3V646 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457246   ⟸   XM_017601757
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K1G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457247   ⟸   XM_017601758
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K1G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071827   ⟸   ENSRNOT00000079207
RefSeq Acc Id: ENSRNOP00000001580   ⟸   ENSRNOT00000001580
RefSeq Acc Id: XP_038954932   ⟸   XM_039099004
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038954930   ⟸   XM_039099002
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V646-F1-model_v2 AlphaFold G3V646 1-338 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
20 10820849 10820850 C T snv LH/MavRrrc (RGD), LN/MavRrrc (RGD), LEW/NCrlBR (RGD), FHL/EurMcwi (RGD), BBDP/Wor (RGD), SR/JrHsd (MCW), GH/OmrMcwi (MCW), FHL/EurMcwi (MCW), SR/JrHsd (RGD), SS/JrHsdMcwi (2019), SR/JrHsd (2020), MWF/Hsd (2019), LN/MavRrrcAek (2020), LL/MavRrrcAek (2020), LH/MavRrrcAek (2020), LEXF3/Stm (2020), LEXF2B/Stm (2019), LEXF1C/Stm (2019), LEXF1A/Stm (2019), LEXF11/Stm (2020), LEW/Crl (2019), GK/FarMcwi (2019), FXLE18/Stm (2020), FHH/EurMcwi (MCW), SBN/Ygl (MCW), SS/JrHsdMcwi (MCW), F344/NRrrc (MCW), F344/NCrl (RGD), FHH/EurMcwi (RGD), GK/Ox (RGD), LEW/Crl (RGD), LL/MavRrrc (RGD), MHS/Gib (RGD), SBN/Ygl (RGD), SS/Jr (RGD), SS/JrHsdMcwi (RGD), F344/DuCrl (2019), F344/NCrl (2019), F344/N (2020), F344/Stm (2019), FHH/EurMcwi (2019)
20 10820860 10820861 C A snv WN/N (2020), CDR, WKY/NCrl (2019), MR/N (2020), M520/N (2020), M520/NRrrcMcwi (2019), LEXF10A/StmMcwi (2020), LE/Stm (2019), LEXF4/Stm (2020), FXLE16/Stm (2020), DA/OlaHsd (2019), BUF/N (2020), WKY/NHsd (RGD), WKY/Gcrc (RGD), WKY/NCrl (RGD), LE/Stm (RGD), WN/N (MCW), WKY/N (MCW), MR/N (MCW), M520/N (MCW), Buf/N (MCW), CDS, WKY/N (2020)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
20 12993033 12993034 C A snv WN/N (KNAW), ZFDM (KyushuU), BUF/N (KNAW), DA/BklArbNsi (KNAW), LE/Stm (Illumina) (KNAW), LE/Stm (SOLiD) (KNAW), M520/N (KNAW), WKY/Gcrc (KNAW), WKY/N (KNAW), WKY/NCrl (KNAW), WKY/NHsd (KNAW), Crl:SD (UDEL), BUF/MNa (KyushuU), LE/Stm (KyushuU), MR/N (KNAW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
20 10430557 10430558 C A snv BUF/N (KNAW), DA/BklArbNsi (ICAHN), M520/N (KNAW), MR/N (KNAW), WKY/N (KNAW), WN/N (KNAW), LE/Stm (ICL), WKY/NCrl (ICL), WKY/Gcrc (ICL), WKY/NHsd (ICL), HCR/1Mco (UMich), LCR/1Mco (UMich), HCR/2Mco (UMich), LCR/2Mco (UMich), LE/Stm (KNAW)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
20 10099726 10099727 C A snv BUF/N (2020), DA/OlaHsd (2019), FXLE16/Stm (2020), LEXF4/Stm (2020), LE/Stm (2019), WN/N (2020), M520/NRrrcMcwi (2019), M520/N (2020), MR/N (2020), WKY/NCrl (2019), WKY/N (2020), LEXF10A/StmMcwi (2020)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565879 AgrOrtholog
BioCyc Gene G2FUF-4289 BioCyc
Ensembl Genes ENSRNOG00000001193 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000001580 ENTREZGENE
  ENSRNOP00000001580.4 UniProtKB/TrEMBL
  ENSRNOP00000071827 ENTREZGENE
  ENSRNOP00000071827.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001580 ENTREZGENE
  ENSRNOT00000001580.7 UniProtKB/TrEMBL
  ENSRNOT00000079207 ENTREZGENE
  ENSRNOT00000079207.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7112979 IMAGE-MGC_LOAD
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  HSF2BP UniProtKB/TrEMBL
KEGG Report rno:499413 UniProtKB/TrEMBL
MGC_CLONE MGC:188036 IMAGE-MGC_LOAD
NCBI Gene 499413 ENTREZGENE
PANTHER PTHR15434 UniProtKB/TrEMBL
PhenoGen Hsf2bp PhenoGen
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A0A0G2K1G2 ENTREZGENE, UniProtKB/TrEMBL
  B0BNC3_RAT UniProtKB/TrEMBL
  G3V646 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Hsf2bp  heat shock transcription factor 2 binding protein  RGD1565879_predicted  similar to heat shock transcription factor 2 binding protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1565879_predicted  similar to heat shock transcription factor 2 binding protein (predicted)  LOC499413  similar to heat shock transcription factor 2 binding protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499413  similar to heat shock transcription factor 2 binding protein      Symbol and Name status set to provisional 70820 PROVISIONAL