Dock2 (dedicator of cytokinesis 2) - Rat Genome Database
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Gene: Dock2 (dedicator of cytokinesis 2) Rattus norvegicus
Analyze
Symbol: Dock2
Name: dedicator of cytokinesis 2
RGD ID: 1564189
Description: Predicted to have GTPase activator activity; Rac guanyl-nucleotide exchange factor activity; and T cell receptor binding activity. Predicted to be involved in several processes, including T cell activation; membrane raft polarization; and myeloid dendritic cell activation involved in immune response. Human ortholog(s) of this gene implicated in immunodeficiency 40. Orthologous to human DOCK2 (dedicator of cytokinesis 2); PARTICIPATES IN chemokine mediated signaling pathway; Fc gamma receptor mediated signaling pathway; INTERACTS WITH 2,6-dinitrotoluene; 3-chloropropane-1,2-diol; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: dedicator of cytokinesis protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Dock2-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01019,181,512 - 19,603,171 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01019,060,032 - 19,481,150 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41019,207,499 - 19,660,353 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1018,459,930 - 18,875,791 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10559471   PMID:11518968   PMID:12176041   PMID:12871644   PMID:19946888   PMID:20458337   PMID:21892172   PMID:25788409   PMID:30716327  


Genomics

Comparative Map Data
Dock2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01019,181,512 - 19,603,171 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01019,060,032 - 19,481,150 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41019,207,499 - 19,660,353 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1018,459,930 - 18,875,791 (-)NCBICelera
Cytogenetic Map10q12NCBI
DOCK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5169,637,268 - 170,083,382 (+)EnsemblGRCh38hg38GRCh38
GRCh385169,637,247 - 170,083,382 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375169,064,251 - 169,510,386 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365168,996,871 - 169,442,959 (+)NCBINCBI36hg18NCBI36
Build 345168,996,870 - 169,442,959NCBI
Celera5165,095,818 - 165,542,012 (+)NCBI
Cytogenetic Map5q35.1NCBI
HuRef5164,162,763 - 164,608,396 (+)NCBIHuRef
CHM1_15168,496,748 - 168,942,815 (+)NCBICHM1_1
Dock2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,176,815 - 34,674,732 (-)NCBIGRCm39mm39
GRCm381134,226,815 - 34,783,905 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,226,815 - 34,783,892 (-)EnsemblGRCm38mm10GRCm38
MGSCv371134,126,864 - 34,414,545 (-)NCBIGRCm37mm9NCBIm37
MGSCv371134,495,792 - 34,597,325 (-)NCBIGRCm37mm9NCBIm37
MGSCv361134,127,668 - 34,414,536 (-)NCBImm8
Celera1138,463,751 - 38,560,177 (-)NCBICelera
Celera1136,638,309 - 36,926,598 (-)NCBICelera
Cytogenetic Map11A4NCBI
Dock2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540822,630,364 - 23,059,899 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540822,630,375 - 23,059,832 (+)NCBIChiLan1.0ChiLan1.0
DOCK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15171,761,545 - 172,206,762 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5171,778,952 - 172,206,238 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05165,000,368 - 165,447,148 (+)NCBIMhudiblu_PPA_v0panPan3
DOCK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl441,780,436 - 42,235,177 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1441,779,950 - 42,177,957 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dock2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366094,695,202 - 5,099,038 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DOCK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1653,843,248 - 54,248,638 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11653,843,248 - 54,248,708 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21658,215,082 - 58,276,353 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DOCK2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12371,866,196 - 72,299,066 (+)NCBI
ChlSab1.1 Ensembl2371,866,251 - 72,299,056 (+)Ensembl
Dock2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473319,882,234 - 20,315,211 (-)NCBI

Position Markers
D10Rat118  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01019,591,557 - 19,591,669NCBIRnor6.0
Rnor_5.01019,469,554 - 19,469,666UniSTSRnor5.0
RGSC_v3.41019,648,781 - 19,648,894RGDRGSC3.4
RGSC_v3.41019,648,782 - 19,648,894UniSTSRGSC3.4
RGSC_v3.11019,649,830 - 19,649,943RGD
Celera1018,864,178 - 18,864,290UniSTS
Cytogenetic Map10q12UniSTS
SHRSP x BN Map1020.45UniSTS
SHRSP x BN Map1020.45RGD
RH143987  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01019,387,308 - 19,387,415NCBIRnor6.0
Rnor_5.01019,264,942 - 19,265,049UniSTSRnor5.0
RGSC_v3.41019,403,721 - 19,403,828UniSTSRGSC3.4
Celera1018,655,547 - 18,655,654UniSTS
Cytogenetic Map10q12UniSTS
RH138702  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01019,330,228 - 19,330,388NCBIRnor6.0
Rnor_5.01019,207,862 - 19,208,022UniSTSRnor5.0
RGSC_v3.41019,346,341 - 19,346,501UniSTSRGSC3.4
Celera1018,598,667 - 18,598,827UniSTS
Cytogenetic Map10q12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109841807108540162Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10587753664401490Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014827894107857673Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10483563820170031Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10521719919591669Rat
737823Alc12Alcohol consumption QTL 124.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)101755538619743866Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101646873661468736Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10622928936185929Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101824639453637634Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101940281464402814Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135538813Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1076442166221621Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138594330Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10752145052521450Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101482789492423564Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014827894110992275Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)10546011921524070Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10546011921524070Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10546011921524070Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10546011921524070Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10546011921524070Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101537547462469074Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10642907599492409Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11712154262121542Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11712154262121542Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101263951357639513Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10129592136Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101263951357639513Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142669970Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10622909575983805Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101263951357639513Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)10144902893Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:76
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000059810
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008767630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AABR07029266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07029267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07029268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07029269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07029270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07029271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AABR07029272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01063134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC101877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_008767630   ⟹   XP_008765852
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01019,181,512 - 19,603,171 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008775695   ⟹   XP_008773917
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1018,459,930 - 18,875,791 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008765852 (Get FASTA)   NCBI Sequence Viewer  
  XP_008773917 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI01878 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_008773917   ⟸   XM_008775695
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008765852   ⟸   XM_008767630
- Peptide Label: isoform X1
- Sequence:
Protein Domains
C2 DOCK-type   SH3


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564189 AgrOrtholog
Gene3D-CATH 1.20.1270.350 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_domain_sf UniProtKB/TrEMBL
  DHR-1_domain UniProtKB/TrEMBL
  DOCK UniProtKB/TrEMBL
  DOCK_2 UniProtKB/TrEMBL
  DOCK_N UniProtKB/TrEMBL
  DOCK_N_sub1 UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene 360509 ENTREZGENE
PANTHER PTHR45653 UniProtKB/TrEMBL
  PTHR45653:SF6 UniProtKB/TrEMBL
Pfam DOCK-C2 UniProtKB/TrEMBL
  DOCK_N UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
PhenoGen Dock2 PhenoGen
PROSITE DHR_1 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/TrEMBL
UniGene Rn.178834 ENTREZGENE
  Rn.227363 ENTREZGENE
  Rn.233418 ENTREZGENE
UniProt Q3MIE5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-02-09 Dock2  dedicator of cytokinesis 2      Symbol and Name status set to provisional 70820 PROVISIONAL