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Gene: Slc4a2 (solute carrier family 4 member 2) Rattus norvegicus
Symbol: Slc4a2
Name: solute carrier family 4 member 2
RGD ID: 3711
Description: Exhibits enzyme binding activity. Involved in digestive tract development; regulation of intracellular pH; and spermatogenesis. Localizes to apical plasma membrane and basolateral plasma membrane. Biomarker of autosomal recessive polycystic kidney disease and prediabetes syndrome. Orthologous to human SLC4A2 (solute carrier family 4 member 2); PARTICIPATES IN bile acid transport pathway; INTERACTS WITH 3',5'-cyclic AMP; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: AE 2; Ae2; AE2 Cl-/HCO3-exchanger, variant AE2b; Aep2; anion exchange protein 2; anion exchanger 2; B3RP-2; band 3-related protein 2; non-erythroid band 3-like protein; solute carrier family 4 (anion exchanger), member 2; Solute carrier family 4 member 2 anion exchange protein 2; solute carrier family 4, member 2; Solute carrier family 4, member 2, anion exchange protein 2
Homo sapiens (human) : SLC4A2 (solute carrier family 4 member 2)  HGNC  Alliance
Mus musculus (house mouse) : Slc4a2 (solute carrier family 4 (anion exchanger), member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc4a2 (solute carrier family 4 member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC4A2 (solute carrier family 4 member 2)
Canis lupus familiaris (dog) : SLC4A2 (solute carrier family 4 member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc4a2 (solute carrier family 4 member 2)
Sus scrofa (pig) : SLC4A2 (solute carrier family 4 member 2)
Chlorocebus sabaeus (African green monkey) : SLC4A2 (solute carrier family 4 member 2)
Heterocephalus glaber (naked mole-rat) : Slc4a2 (solute carrier family 4 member 2)
more info ...
Is Marker For: QTLs:   BpQTLcluster5  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.047,264,677 - 7,282,355 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl47,264,683 - 7,281,223 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.047,276,041 - 7,294,088 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.446,100,783 - 6,117,982 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.146,100,782 - 6,117,982 (-)NCBI
Celera46,350,986 - 6,367,533 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc4a2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3711
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.