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Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | autistic disorder | | ISO | RGD:736453 | 8554872 | ClinVar more ... | ClinVar | PMID:28972980 | |
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Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | autistic disorder | | ISO | RGD:736453 | 8554872 | ClinVar more ... | ClinVar | PMID:28972980 | |
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1. | Arac D, etal., Neuron. 2007 Dec 20;56(6):992-1003. |
2. | Barrow SL, etal., Neural Dev. 2009 May 18;4:17. doi: 10.1186/1749-8104-4-17. |
3. | Boucard AA, etal., Neuron. 2005 Oct 20;48(2):229-36. doi: 10.1016/j.neuron.2005.08.026. |
4. | Chen X, etal., Nat Struct Mol Biol. 2008 Jan;15(1):50-6. Epub 2007 Dec 16. |
5. | Chih B, etal., Neuron. 2006 Jul 20;51(2):171-8. doi: 10.1016/j.neuron.2006.06.005. |
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7. | Chubykin AA, etal., J Biol Chem. 2005 Jun 10;280(23):22365-74. Epub 2005 Mar 29. |
8. | Chubykin AA, etal., Neuron. 2007 Jun 21;54(6):919-31. |
9. | Clarris HJ, etal., Int J Dev Biol 2002;46(4):649-52. |
10. | Comoletti D, etal., J Biol Chem. 2003 Dec 12;278(50):50497-505. Epub 2003 Sep 30. |
11. | Constance WD, etal., Elife. 2018 Mar 5;7. pii: 31659. doi: 10.7554/eLife.31659. |
12. | Dresbach T, etal., Mol Cell Neurosci. 2004 Nov;27(3):227-35. |
13. | Fang M, etal., Mol Neurobiol. 2016 Jan;53(1):270-84. doi: 10.1007/s12035-014-8999-8. Epub 2014 Nov 27. |
14. | Fu Z, etal., J Neurophysiol. 2003 Dec;90(6):3950-7. Epub 2003 Aug 20. |
15. | Futai K, etal., Nat Neurosci. 2007 Feb;10(2):186-95. Epub 2007 Jan 21. |
16. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
17. | Gjørlund MD, etal., FASEB J. 2012 Oct;26(10):4174-86. doi: 10.1096/fj.11-202242. Epub 2012 Jun 29. |
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21. | Jackson J, etal., PLoS One. 2012;7(4):e35557. doi: 10.1371/journal.pone.0035557. Epub 2012 Apr 23. |
22. | Ko J, etal., EMBO J. 2009 Oct 21;28(20):3244-55. doi: 10.1038/emboj.2009.249. Epub 2009 Sep 3. |
23. | Leone P, etal., EMBO J. 2010 Jul 21;29(14):2461-71. doi: 10.1038/emboj.2010.123. Epub 2010 Jun 11. |
24. | MGD data from the GO Consortium |
25. | Mondin M, etal., J Neurosci. 2011 Sep 21;31(38):13500-15. doi: 10.1523/JNEUROSCI.6439-10.2011. |
26. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
27. | Nguyen T and Sudhof TC, J Biol Chem. 1997 Oct 10;272(41):26032-9. |
28. | Paskus JD, etal., Cell Rep. 2019 Dec 3;29(10):2944-2952.e5. doi: 10.1016/j.celrep.2019.10.115. |
29. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
30. | RGD automated import pipeline for gene-chemical interactions |
31. | Scheiffele P, etal., Cell. 2000 Jun 9;101(6):657-69. |
32. | Shipman SL and Nicoll RA, Neuron. 2012 Oct 18;76(2):309-16. doi: 10.1016/j.neuron.2012.07.024. Epub 2012 Oct 17. |
33. | Song JY, etal., Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):1100-5. |
34. | Stan A, etal., Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):11116-21. doi: 10.1073/pnas.0914233107. Epub 2010 Jun 1. |
35. | Suckow AT, etal., J Biol Chem. 2012 Jun 8;287(24):19816-26. doi: 10.1074/jbc.M111.280537. Epub 2012 Apr 23. |
36. | Wang D, etal., Biomed Res Int. 2017;2017:1209360. doi: 10.1155/2017/1209360. Epub 2017 Jan 18. |
37. | Wittenmayer N, etal., Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13564-9. doi: 10.1073/pnas.0905819106. Epub 2009 Jul 23. |
PMID:9694864 | PMID:11329178 | PMID:12202822 | PMID:12796785 | PMID:14769026 | PMID:15458844 | PMID:15620359 | PMID:16298368 | PMID:16982420 | PMID:17474715 | PMID:18334216 | PMID:18579781 |
PMID:18755801 | PMID:19098102 | PMID:19105974 | PMID:20176955 | PMID:20573900 | PMID:20739565 | PMID:20869594 | PMID:21056983 | PMID:21356198 | PMID:21532576 | PMID:21788371 | PMID:21911064 |
PMID:22671294 | PMID:22840401 | PMID:22960622 | PMID:23143522 | PMID:23269831 | PMID:23426688 | PMID:23716671 | PMID:23791195 | PMID:24613359 | PMID:24860089 | PMID:25157101 | PMID:26325471 |
PMID:26440732 | PMID:26771491 | PMID:27423632 | PMID:28875935 | PMID:29592780 | PMID:30049666 | PMID:30790215 | PMID:32915137 | PMID:34353896 |
Nlgn1 (Rattus norvegicus - Norway rat) |
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NLGN1 (Homo sapiens - human) |
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Nlgn1 (Mus musculus - house mouse) |
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Nlgn1 (Chinchilla lanigera - long-tailed chinchilla) |
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NLGN1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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NLGN1 (Canis lupus familiaris - dog) |
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Nlgn1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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NLGN1 (Sus scrofa - pig) |
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NLGN1 (Chlorocebus sabaeus - green monkey) |
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Nlgn1 (Heterocephalus glaber - naked mole-rat) |
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D2Rat335 |
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BF394648 |
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The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 64 | ||||||||||||
Low | 12 | 4 | 8 | 4 | 10 | 30 | 2 | ||||||
Below cutoff | 3 | 16 | 13 | 5 | 1 | 5 | 4 | 4 | 23 | 7 | 7 | 4 |
RefSeq Transcripts | NM_053868 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_008760890 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017590583 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017590584 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017590585 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017590586 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017590587 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017590588 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017590589 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017590590 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039101567 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039101568 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039101569 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039101570 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039101571 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039101572 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039101573 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039101574 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039101575 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039101576 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039101577 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039101578 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | CH473961 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
JACYVU010000067 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
U22952 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000041111 ⟹ ENSRNOP00000040172 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000092660 ⟹ ENSRNOP00000075793 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000107850 ⟹ ENSRNOP00000094652 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_053868 ⟹ NP_446320 | ||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017590583 ⟹ XP_017446072 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017590590 ⟹ XP_017446079 | ||||||||||||
RefSeq Status: | |||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039101567 ⟹ XP_038957495 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039101568 ⟹ XP_038957496 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039101569 ⟹ XP_038957497 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039101570 ⟹ XP_038957498 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039101571 ⟹ XP_038957499 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039101572 ⟹ XP_038957500 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039101573 ⟹ XP_038957501 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039101574 ⟹ XP_038957502 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039101575 ⟹ XP_038957503 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039101576 ⟹ XP_038957504 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039101577 ⟹ XP_038957505 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_039101578 ⟹ XP_038957506 | ||||||||
RefSeq Status: | |||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_446320 | (Get FASTA) | NCBI Sequence Viewer |
XP_017446072 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017446079 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038957495 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038957496 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038957497 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038957498 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038957499 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038957500 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038957501 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038957502 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038957503 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038957504 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038957505 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038957506 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAA85720 | (Get FASTA) | NCBI Sequence Viewer |
EDM01096 | (Get FASTA) | NCBI Sequence Viewer | |
Q62765 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_446320 ⟸ NM_053868 |
- Peptide Label: | precursor |
- UniProtKB: | Q62765 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | XP_017446079 ⟸ XM_017590590 |
- Peptide Label: | isoform X6 |
- UniProtKB: | Q62765 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | XP_017446072 ⟸ XM_017590583 |
- Peptide Label: | isoform X5 |
- UniProtKB: | Q62765 (UniProtKB/Swiss-Prot) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000040172 ⟸ ENSRNOT00000041111 |
RefSeq Acc Id: | ENSRNOP00000075793 ⟸ ENSRNOT00000092660 |
RefSeq Acc Id: | XP_038957500 ⟸ XM_039101572 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_038957501 ⟸ XM_039101573 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_038957497 ⟸ XM_039101569 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_038957498 ⟸ XM_039101570 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_038957499 ⟸ XM_039101571 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_038957496 ⟸ XM_039101568 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_038957504 ⟸ XM_039101576 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_038957506 ⟸ XM_039101578 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | XP_038957502 ⟸ XM_039101574 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_038957495 ⟸ XM_039101567 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_038957505 ⟸ XM_039101577 |
- Peptide Label: | isoform X3 |
RefSeq Acc Id: | XP_038957503 ⟸ XM_039101575 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | ENSRNOP00000094652 ⟸ ENSRNOT00000107850 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q62765-F1-model_v2 | AlphaFold | Q62765 | 1-843 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:621117 | AgrOrtholog |
BioCyc Gene | G2FUF-53532 | BioCyc |
Ensembl Genes | ENSRNOG00000032576 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Ensembl Protein | ENSRNOP00000040172 | ENTREZGENE, UniProtKB/TrEMBL |
ENSRNOP00000075793 | ENTREZGENE, UniProtKB/Swiss-Prot | |
ENSRNOP00000094652 | ENTREZGENE | |
Ensembl Transcript | ENSRNOT00000041111 | ENTREZGENE, UniProtKB/TrEMBL |
ENSRNOT00000092660 | ENTREZGENE, UniProtKB/Swiss-Prot | |
ENSRNOT00000107850 | ENTREZGENE | |
Gene3D-CATH | 3.40.50.1820 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
InterPro | AB_hydrolase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
CarbesteraseB | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Carboxylesterase_B_CS | UniProtKB/Swiss-Prot | |
Nlgn | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
NLGN1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:116647 | UniProtKB/Swiss-Prot |
NCBI Gene | 116647 | ENTREZGENE |
PANTHER | PTHR43903:SF2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Pfam | COesterase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PhenoGen | Nlgn1 | PhenoGen |
PRINTS | NEUROLIGIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PROSITE | CARBOXYLESTERASE_B_2 | UniProtKB/Swiss-Prot |
Superfamily-SCOP | SSF53474 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A0A0H2UHW8_RAT | UniProtKB/TrEMBL |
NLGN1_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2004-02-26 | Nlgn1 | neuroligin 1 | Symbol and Name status set to approved | 625702 | APPROVED | ||
2002-08-07 | Nlgn1 | neuroligin 1 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
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gene_expression | expressed by second order mitral cells during early postnatal development in the olfactory bulb | 727397 |