Gene: Scnn1b (sodium channel epithelial 1 beta subunit) Rattus norvegicus
Symbol: Scnn1b
Name: sodium channel epithelial 1 beta subunit
Description: ENCODES a protein that exhibits ligand-gated sodium channel activity; WW domain binding; sodium channel activity (ortholog); INVOLVED IN regulation of sodium ion transport; response to hypoxia; sodium ion transport; PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH Nephrotic Syndrome; Adrenal Insufficiency (ortholog); autosomal recessive pseudohypoaldosteronism type 1 (ortholog); FOUND IN apical plasma membrane; cell surface; external side of plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl
Type: protein-coding
Also known as: amiloride-sensitive sodium channel subunit beta; beta-ENaC; beta-NaCH; epithelial Na(+) channel subunit beta; nonvoltage-gated sodium channel 1 subunit beta; RNENACB; SCNEB; Sodium channel nonvoltage-gated 1 beta (epithelial); sodium channel, non-voltage-gated 1, beta subunit; sodium channel, nonvoltage-gated 1 beta; sodium channel, nonvoltage-gated 1, beta; sodium channel, nonvoltage-gated, type I, beta
Homo sapiens (human) : SCNN1B (sodium channel epithelial 1 beta subunit)  HGNC  AGR
Mus musculus (house mouse) : Scnn1b (sodium channel, nonvoltage-gated 1 beta)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Scnn1b (sodium channel epithelial 1 beta subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SCNN1B (sodium channel epithelial 1 beta subunit)
Canis lupus familiaris (dog) : SCNN1B (sodium channel epithelial 1 beta subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scnn1b (sodium channel epithelial 1 beta subunit)
more info ...
Is Marker For: Strains:   SHR.BN-(D1Mit3-Igf2)/Ipcv  
QTLs:   Bp88  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01191,829,547 - 191,883,991 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01198,932,512 - 198,953,453 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41180,682,622 - 180,748,068 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11180,822,536 - 180,887,983 (+)NCBI
Celera1174,140,255 - 174,194,462 (+)NCBICelera
Cytogenetic Map1q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Scnn1b
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3640
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE