CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 3,3',4,4',5-pentachlorobiphenyl
Accession: CHEBI:34317
browse the term
Definition: A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Synonyms: exact_synonym: 3,3',4,4',5-pentachloro-1,1'-biphenyl
related_synonym: 3,4,5,3',4'-Penta coplanar polychlorinated biphenyl; Formula=C12H5Cl5; InChI=1S/C12H5Cl5/c13-8-2-1-6(3-9(8)14)7-4-10(15)12(17)11(16)5-7/h1-5H; InChIKey=REHONNLQRWTIFF-UHFFFAOYSA-N; PCB 126; SMILES=Clc1ccc(cc1Cl)-c1cc(Cl)c(Cl)c(Cl)c1
xref: CAS:57465-28-8; KEGG:C14573
xref_mesh: MESH:C023035
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A2m
alpha-2-macroglobulin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of A2M mRNA
CTD
PMID:19692669
NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186
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Aacs
acetoacetyl-CoA synthetase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AACS mRNA
CTD
PMID:23196670
NCBI chr 5:125,552,937...125,594,469
Ensembl chr 5:125,552,878...125,594,474
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Aadac
arylacetamide deacetylase
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AADAC mRNA
CTD
PMID:22429928
NCBI chr 3:59,939,209...59,947,578
Ensembl chr 3:59,933,138...59,947,581
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Aadat
aminoadipate aminotransferase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AADAT mRNA
CTD
PMID:20959002
NCBI chr 8:60,958,877...60,998,711
Ensembl chr 8:60,958,966...60,998,711
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Aatk
apoptosis-associated tyrosine kinase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AATK mRNA
CTD
PMID:32119087
NCBI chr11:119,898,137...119,938,009
Ensembl chr11:119,898,139...119,937,993
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Abca1
ATP-binding cassette, sub-family A member 1
increases expression affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCA1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of ABCA1 mRNA
CTD
PMID:21703328
NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
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Abcc2
ATP-binding cassette, sub-family member 2
multiple interactions increases expression decreases expression
EXP ISO
[3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCC2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ABCC2 mRNA
CTD
PMID:15833929 PMID:32119087
NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
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Abcc3
ATP-binding cassette, sub-family C member 3
multiple interactions increases expression
EXP ISO
[3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCC3 mRNA
CTD
PMID:15833929 PMID:20959002 PMID:23994337
NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
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Abcc5
ATP-binding cassette, sub-family C member 5
multiple interactions increases expression decreases expression
EXP ISO
[3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC5 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCC5 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ABCC5 mRNA
CTD
PMID:15833929 PMID:16260000 PMID:23196670
NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144
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Abcc6
ATP-binding cassette, sub-family C member 6
multiple interactions increases expression
EXP
[3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC6 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCC6 mRNA
CTD
PMID:15833929
NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726
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Abcd4
ATP-binding cassette, sub-family D member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ABCD4 mRNA
CTD
PMID:23196670
NCBI chr12:84,648,634...84,664,259
Ensembl chr12:84,648,238...84,664,187
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Abcg1
ATP binding cassette subfamily G member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCG1 mRNA
CTD
PMID:23196670
NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962
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Abcg2
ATP binding cassette subfamily G member 2 (Junior blood group)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCG2 mRNA
CTD
PMID:29947894 PMID:35618242
NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
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Abhd5
abhydrolase domain containing 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ABHD5 mRNA
CTD
PMID:23196670
NCBI chr 9:122,180,681...122,210,589
Ensembl chr 9:122,180,673...122,210,589
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Acaa1b
acetyl-Coenzyme A acyltransferase 1B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACAA1B mRNA
CTD
PMID:20959002
NCBI chr 9:118,977,111...118,986,149
Ensembl chr 9:118,977,091...118,986,161
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Acaa2
acetyl-CoA acyltransferase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACAA2 mRNA
CTD
PMID:23196670
NCBI chr18:74,912,283...74,939,278
Ensembl chr18:74,912,268...74,939,279
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Acaca
acetyl-Coenzyme A carboxylase alpha
multiple interactions decreases expression
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of ACACA mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACACA mRNA
CTD
PMID:28973532 PMID:37080397
NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
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Acat2
acetyl-Coenzyme A acetyltransferase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACAT2 mRNA
CTD
PMID:23196670
NCBI chr17:13,161,929...13,179,612
Ensembl chr17:13,161,777...13,179,634
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Ackr3
atypical chemokine receptor 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACKR3 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 1:90,131,702...90,143,446
Ensembl chr 1:90,131,702...90,144,473
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Acot3
acyl-CoA thioesterase 3
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ACOT3 mRNA
CTD
PMID:20702594
NCBI chr12:84,098,918...84,107,174
Ensembl chr12:84,098,918...84,107,176
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Acot7
acyl-CoA thioesterase 7
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACOT7 mRNA
CTD
PMID:23994337
NCBI chr 4:152,258,872...152,356,312
Ensembl chr 4:152,262,591...152,356,312
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Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACOX1 mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACOX1 mRNA]
CTD
PMID:26396156 PMID:34848246
NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
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Acox3
acyl-Coenzyme A oxidase 3, pristanoyl
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACOX3 mRNA
CTD
PMID:23196670
NCBI chr 5:35,740,293...35,772,397
Ensembl chr 5:35,740,384...35,772,696
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Acp2
acid phosphatase 2, lysosomal
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACP2 mRNA
CTD
PMID:20959002
NCBI chr 2:91,033,157...91,044,443
Ensembl chr 2:91,033,230...91,044,443
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Acp3
acid phosphatase 3
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ACP3 mRNA
CTD
PMID:20702594
NCBI chr 9:104,165,439...104,214,921
Ensembl chr 9:104,165,450...104,214,947
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Acsbg2
acyl-CoA synthetase bubblegum family member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACSBG2 mRNA
CTD
PMID:23146750
NCBI chr17:57,150,103...57,181,505
Ensembl chr17:57,150,103...57,181,447
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Acsl3
acyl-CoA synthetase long-chain family member 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACSL3 mRNA
CTD
PMID:23196670
NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460
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Acsl5
acyl-CoA synthetase long-chain family member 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACSL5 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr19:55,240,298...55,285,060
Ensembl chr19:55,240,370...55,286,152
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Acsm2
acyl-CoA synthetase medium-chain family member 2
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of ACSM2 mRNA
CTD
PMID:16984957
NCBI chr 7:119,153,563...119,199,917
Ensembl chr 7:119,153,563...119,199,913
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Acta1
actin alpha 1, skeletal muscle
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACTA1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACTA1 mRNA
CTD
PMID:19692669 PMID:32119087
NCBI chr 8:124,618,497...124,621,514
Ensembl chr 8:124,618,508...124,621,490
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Actg2
actin, gamma 2, smooth muscle, enteric
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACTG2 mRNA
CTD
PMID:32119087
NCBI chr 6:83,489,891...83,513,233
Ensembl chr 6:83,489,887...83,513,247
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Actl7b
actin-like 7b
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACTL7B mRNA
CTD
PMID:23146750
NCBI chr 4:56,740,005...56,741,425
Ensembl chr 4:56,740,005...56,741,443
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Actn4
actinin alpha 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACTN4 mRNA
CTD
PMID:23196670
NCBI chr 7:28,592,673...28,661,799
Ensembl chr 7:28,592,673...28,661,765
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Actrt2
actin-related protein T2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACTRT2 mRNA
CTD
PMID:23146750
NCBI chr 4:154,750,885...154,752,324
Ensembl chr 4:154,750,890...154,752,324
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Acvr1
activin A receptor, type 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACVR1 mRNA
CTD
PMID:23196670
NCBI chr 2:58,336,450...58,456,840
Ensembl chr 2:58,278,656...58,457,169
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Acy1
aminoacylase 1
increases expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ACY1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACY1 mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr 9:106,310,180...106,315,594
Ensembl chr 9:106,310,180...106,315,518
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Adam11
a disintegrin and metallopeptidase domain 11
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADAM11 mRNA
CTD
PMID:32119087
NCBI chr11:102,652,261...102,671,089
Ensembl chr11:102,652,265...102,671,088
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Adam17
a disintegrin and metallopeptidase domain 17
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADAM17 mRNA
CTD
PMID:23196670
NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633
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Adam2
a disintegrin and metallopeptidase domain 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADAM2 mRNA
CTD
PMID:23994337
NCBI chr14:66,264,778...66,315,300
Ensembl chr14:66,264,778...66,315,182
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Adamts1
ADAM metallopeptidase with thrombospondin type 1 motif 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADAMTS1 mRNA
CTD
PMID:23196670
NCBI chr16:85,590,715...85,600,001
Ensembl chr16:85,590,715...85,600,001
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Adamts4
ADAM metallopeptidase with thrombospondin type 1 motif 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADAMTS4 mRNA
CTD
PMID:35618242
NCBI chr 1:171,077,698...171,089,836
Ensembl chr 1:171,077,990...171,088,206
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Adamts5
ADAM metallopeptidase with thrombospondin type 1 motif 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADAMTS5 mRNA
CTD
PMID:23196670
NCBI chr16:85,655,045...85,698,013
Ensembl chr16:85,653,061...85,698,716
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Adamts7
ADAM metallopeptidase with thrombospondin type 1 motif 7
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADAMTS7 mRNA
CTD
PMID:35618242
NCBI chr 9:90,041,420...90,082,155
Ensembl chr 9:90,045,122...90,090,124
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Adamtsl2
ADAMTS-like 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADAMTSL2 mRNA
CTD
PMID:23146750
NCBI chr 2:26,969,348...26,998,993
Ensembl chr 2:26,969,391...26,998,993
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Adamtsl3
ADAMTS-like 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADAMTSL3 mRNA
CTD
PMID:32119087
NCBI chr 7:81,984,612...82,263,658
Ensembl chr 7:81,984,902...82,263,658
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Adamtsl5
ADAMTS-like 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADAMTSL5 mRNA
CTD
PMID:23146750
NCBI chr10:80,175,655...80,184,246
Ensembl chr10:80,174,944...80,184,246
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Adcy4
adenylate cyclase 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADCY4 mRNA
CTD
PMID:23196670
NCBI chr14:56,006,513...56,021,552
Ensembl chr14:56,006,514...56,021,552
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Adcyap1r1
adenylate cyclase activating polypeptide 1 receptor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADCYAP1R1 mRNA
CTD
PMID:32119087
NCBI chr 6:55,428,486...55,478,440
Ensembl chr 6:55,428,963...55,478,436
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Add3
adducin 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADD3 mRNA
CTD
PMID:23196670
NCBI chr19:53,128,874...53,235,518
Ensembl chr19:53,128,874...53,235,830
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Adgrg1
adhesion G protein-coupled receptor G1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADGRG1 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 8:95,701,321...95,740,836
Ensembl chr 8:95,701,379...95,740,845
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Adgrg2
adhesion G protein-coupled receptor G2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADGRG2 mRNA
CTD
PMID:19692669
NCBI chr X:159,173,315...159,281,072
Ensembl chr X:159,173,686...159,281,066
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Adh1
alcohol dehydrogenase 1 (class I)
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADH1 mRNA]
CTD
PMID:34256052
NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459
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Adh4
alcohol dehydrogenase 4 (class II), pi polypeptide
decreases expression multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADH4 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADH4 mRNA]
CTD
PMID:27055685 PMID:34256052
NCBI chr 3:138,121,217...138,138,444
Ensembl chr 3:138,121,227...138,136,653
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Adh6b
alcohol dehydrogenase 6B (class V)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADH6 mRNA
CTD
PMID:27055685
NCBI chr 3:138,047,176...138,064,621
Ensembl chr 3:138,047,536...138,064,622
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Adh7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADH7 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADH7 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 3:137,903,828...137,937,803
Ensembl chr 3:137,923,521...137,939,143
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Adipoq
adiponectin, C1Q and collagen domain containing
affects expression multiple interactions decreases expression increases expression increases secretion
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ADIPOQ mRNA 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADIPOQ mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADIPOQ protein 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of ADIPOQ protein
CTD
PMID:21703328 PMID:23146750 PMID:25304490 PMID:29474705 PMID:33026256
NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
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Adipor1
adiponectin receptor 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ADIPOR1 mRNA
CTD
PMID:37080397
NCBI chr 1:134,343,116...134,361,089
Ensembl chr 1:134,343,116...134,361,089
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Adipor2
adiponectin receptor 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADIPOR2 mRNA
CTD
PMID:20959002
NCBI chr 6:119,330,111...119,394,489
Ensembl chr 6:119,330,111...119,394,665
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Adm
adrenomedullin
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADM mRNA
CTD
PMID:37080397
NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027
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Adora2a
adenosine A2a receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADORA2A mRNA
CTD
PMID:23196670
NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
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Adra1b
adrenergic receptor, alpha 1b
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADRA1B mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADRA1B mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr11:43,665,432...43,792,076
Ensembl chr11:43,665,433...43,792,037
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Adrb2
adrenergic receptor, beta 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ADRB2 mRNA
CTD
PMID:23196670
NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
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Adtrp
androgen dependent TFPI regulating protein
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of ADTRP mRNA
CTD
PMID:30744511
NCBI chr13:41,916,621...42,001,092
Ensembl chr13:41,916,624...42,001,160
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Afm
afamin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AFM mRNA
CTD
PMID:20959002
NCBI chr 5:90,666,808...90,701,403
Ensembl chr 5:90,666,791...90,701,402
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Afp
alpha fetoprotein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AFP mRNA
CTD
PMID:20959002
NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766
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Agtr1a
angiotensin II receptor, type 1a
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AGTR1 mRNA
CTD
PMID:14962509
NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850
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Ahi1
Abelson helper integration site 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHI1 mRNA
CTD
PMID:23196670
NCBI chr10:20,827,274...20,956,328
Ensembl chr10:20,828,446...20,956,328
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Ahnak
AHNAK nucleoprotein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AHNAK mRNA
CTD
PMID:19692669
NCBI chr19:8,966,640...9,054,299
Ensembl chr19:8,966,648...9,054,278
G
Ahnak2
AHNAK nucleoprotein 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AHNAK2 mRNA
CTD
PMID:32119087
NCBI chr12:112,738,631...112,766,278
Ensembl chr12:112,738,628...112,766,277
G
Ahr
aryl-hydrocarbon receptor
affects binding multiple interactions decreases expression affects response to substance increases activity increases expression affects expression decreases response to substance increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein 3,4,5,3',4'-pentachlorobiphenyl binds to and results in increased activity of AHR protein; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [6,2',4'-trimethoxyflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM protein]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]; AHR protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; Oxygen deficiency affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of AHR protein] 3,4,5,3',4'-pentachlorobiphenyl binds to and affects the localization of AHR protein; 3,4,5,3',4'-pentachlorobiphenyl binds to and results in increased activity of AHR protein; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in decreased expression of AHR mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]; [2,3,7,8-tetrachlorodibenzofuran co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of AHR protein; [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC2 mRNA; [3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC3 mRNA; [3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC5 mRNA; [3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC6 mRNA; [3,4,5,3',4'-pentachlorobiphenyl binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] results in increased expression of AHR mRNA; [AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AHR mRNA] AHR mRNA affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHR mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHR protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl binds to and results in increased activity of AHR protein]; 3,4,5,3',4'-pentachlorobiphenyl binds to and results in increased activity of AHR protein; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; [AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased expression of CCL11 mRNA; [AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased expression of CCL22 mRNA; [AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased expression of IL11 mRNA; [AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in increased secretion of LHB protein; AHR affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GGT1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPX1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADH1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ADH4 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHR mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALAD mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALDH1A1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALOX15 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALOX5 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AOC1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARNT mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CES2C mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CHST1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP17A1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP19A1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP27B1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2B3 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2C13 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2C6 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2C7 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2E1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP3A23-3A1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FBP1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GCKR mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPX2 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPX5 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM3 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTP1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HK2 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B2 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B3 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LPO mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MARCKS mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MPO mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MTHFR mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NOS2 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKLR mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SRD5A1 mRNA]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of XDH mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ACOX1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CREM mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G6PC1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMGCS2 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGF1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PC mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PYGL mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC2A2 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PPARA mRNA]; AHR protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Selenic Acid deficiency inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHR mRNA]; Selenic Acid inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHR mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of AHR mRNA AHR gene mutant form results in decreased susceptibility to 3,4,5,3',4'-pentachlorobiphenyl AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl; AHR protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl 3,3',4,4',5-pentachlorobiphenyl, PCB-126, increases expression of mRNA in rat liver
CTD RGD
PMID:10448124 PMID:11752103 PMID:12628580 PMID:12850102 PMID:15071172 PMID:15352264 PMID:15371557 PMID:15598615 PMID:15833929 PMID:15908097 PMID:15919853 PMID:15990133 PMID:16049271 PMID:16489053 PMID:16705413 PMID:18835618 PMID:19447902 PMID:19692669 PMID:20435555 PMID:20634293 PMID:20728228 PMID:20961953 PMID:21292640 PMID:21775728 PMID:21781905 PMID:21865291 PMID:22262711 PMID:22266287 PMID:22521833 PMID:23644946 PMID:24355420 PMID:24378064 PMID:24812009 PMID:24950391 PMID:25530946 PMID:25654323 PMID:26006071 PMID:26396156 PMID:28284859 PMID:30312631 PMID:31563530 PMID:32119087 PMID:34256052 PMID:34848246 PMID:37080397 PMID:23644946 More...
RGD:401794573
NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
G
Ahrr
aryl-hydrocarbon receptor repressor
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AHRR mRNA
CTD
PMID:21703328 PMID:23146750 PMID:23196670 PMID:29738842 PMID:31563530 PMID:32119087 More...
NCBI chr13:74,359,237...74,440,450
Ensembl chr13:74,359,237...74,440,450
G
Ahsp
alpha hemoglobin stabilizing protein
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of AHSP mRNA
CTD
PMID:30744511
NCBI chr 7:127,902,016...127,902,926
Ensembl chr 7:127,901,969...127,902,930
G
Ak3
adenylate kinase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AK3 mRNA
CTD
PMID:23196670
NCBI chr19:28,968,715...29,026,122
Ensembl chr19:28,998,233...29,025,361
G
Akap12
A kinase anchor protein 12
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AKAP12 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr10:4,216,329...4,309,471
Ensembl chr10:4,216,380...4,309,470
G
Akap17b
A kinase anchor protein 17B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AKAP17B mRNA
CTD
PMID:32119087
NCBI chr X:35,871,832...35,909,021
Ensembl chr X:35,871,967...35,909,048
G
Akap5
A kinase anchor protein 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AKAP5 mRNA
CTD
PMID:23196670
NCBI chr12:76,371,652...76,380,925
Ensembl chr12:76,371,665...76,380,927
G
Akr1c21
aldo-keto reductase family 1, member C21
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of AKR1C2 mRNA
CTD
PMID:30744511
NCBI chr13:4,624,074...4,636,542
Ensembl chr13:4,624,074...4,636,540
G
Akr1c6
aldo-keto reductase family 1, member C6
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of AKR1C1 mRNA
CTD
PMID:30744511
NCBI chr13:4,484,354...4,507,529
Ensembl chr13:4,484,305...4,507,876
G
Akr1d1
aldo-keto reductase family 1, member D1
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AKR1D1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AKR1D1 mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr 6:37,506,913...37,551,856
Ensembl chr 6:37,507,108...37,545,750
G
Akt1
thymoma viral proto-oncogene 1
affects expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of AKT1 mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in increased phosphorylation of AKT1 protein]
CTD
PMID:21703328 PMID:24709675
NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
G
Alad
aminolevulinate, delta-, dehydratase
decreases expression increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALAD mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALAD mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALAD mRNA]
CTD
PMID:20959002 PMID:34256052
NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155
G
Alas1
aminolevulinic acid synthase 1
multiple interactions increases expression affects expression decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of ALAS1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALAS1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of ALAS1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALAS1 mRNA
CTD
PMID:16984957 PMID:19692669 PMID:20959002 PMID:21703328
NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853
G
Alas2
aminolevulinic acid synthase 2, erythroid
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALAS2 mRNA
CTD
PMID:20959002
NCBI chr X:149,330,443...149,353,614
Ensembl chr X:149,330,371...149,353,634
G
Alb
albumin
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALB mRNA
CTD
PMID:23994337
NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
G
Alcam
activated leukocyte cell adhesion molecule
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of ALCAM mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALCAM mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr16:52,069,359...52,273,444
Ensembl chr16:52,069,359...52,274,437
G
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
decreases expression multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALDH1A1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALDH1A1 mRNA]
CTD
PMID:19692669 PMID:34256052
NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
G
Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALDH1A3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALDH1A3 mRNA
CTD
PMID:23196670 PMID:29947894 PMID:32119087
NCBI chr 7:66,040,640...66,077,225
Ensembl chr 7:66,040,638...66,077,265
G
Aldh2
aldehyde dehydrogenase 2, mitochondrial
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALDH2 mRNA
CTD
PMID:19692669
NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887
G
Aldh3a1
aldehyde dehydrogenase family 3, subfamily A1
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALDH3A1 mRNA
CTD
PMID:19692669 PMID:20959002 PMID:23196670 PMID:23994337 PMID:29738842 PMID:32119087 More...
NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247
G
Aldh3b1
aldehyde dehydrogenase 3 family, member B1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALDH3B1 mRNA
CTD
PMID:23196670
NCBI chr19:3,963,491...3,980,898
Ensembl chr19:3,963,491...3,979,808
G
Aldob
aldolase B, fructose-bisphosphate
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALDOB mRNA
CTD
PMID:19692669
NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546
G
Aldoc
aldolase C, fructose-bisphosphate
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALDOC mRNA
CTD
PMID:23196670
NCBI chr11:78,213,899...78,218,607
Ensembl chr11:78,213,794...78,218,607
G
Alox15
arachidonate 15-lipoxygenase
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALOX15 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALOX15 mRNA]
CTD
PMID:34256052
NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857
G
Alox5
arachidonate 5-lipoxygenase
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALOX5 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALOX5 mRNA]
CTD
PMID:34256052
NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
G
Alpl
alkaline phosphatase, liver/bone/kidney
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ALPL mRNA
CTD
PMID:23196670
NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695
G
Ambp
alpha 1 microglobulin/bikunin precursor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AMBP mRNA
CTD
PMID:19692669
NCBI chr 4:63,061,512...63,072,409
Ensembl chr 4:63,061,512...63,073,036
G
Amh
anti-Mullerian hormone
decreases secretion
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of AMH protein
CTD
PMID:34256052
NCBI chr10:80,641,074...80,643,513
Ensembl chr10:80,641,077...80,643,482
G
Amph
amphiphysin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AMPH mRNA
CTD
PMID:23196670
NCBI chr13:19,132,524...19,335,089
Ensembl chr13:19,132,375...19,335,091
G
Angptl2
angiopoietin-like 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ANGPTL2 mRNA
CTD
PMID:23196670
NCBI chr 2:33,105,963...33,137,737
Ensembl chr 2:33,106,081...33,137,729
G
Angptl4
angiopoietin-like 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ANGPTL4 mRNA
CTD
PMID:35618242
NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
G
Angptl8
angiopoietin-like 8
multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of ANGPTL8 mRNA]
CTD
PMID:30312631
NCBI chr 9:21,746,806...21,748,643
Ensembl chr 9:21,746,806...21,748,643
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Ank
progressive ankylosis
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ANK mRNA
CTD
PMID:23196670
NCBI chr15:27,466,763...27,594,995
Ensembl chr15:27,466,763...27,594,995
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Anp32e
acidic nuclear phosphoprotein 32 family member E
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ANP32E mRNA
CTD
PMID:23196670
NCBI chr 3:95,836,557...95,854,699
Ensembl chr 3:95,836,558...95,854,702
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Anpep
alanyl aminopeptidase, membrane
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ANPEP mRNA
CTD
PMID:35618242
NCBI chr 7:79,471,551...79,497,958
Ensembl chr 7:79,471,551...79,510,807
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Anxa2
annexin A2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ANXA2 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077
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Anxa4
annexin A4
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ANXA4 mRNA
CTD
PMID:23994337
NCBI chr 6:86,713,822...86,770,616
Ensembl chr 6:86,713,822...86,770,566
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Anxa5
annexin A5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ANXA5 mRNA
CTD
PMID:20959002
NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043
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Anxa8
annexin A8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ANXA8 mRNA
CTD
PMID:32119087
NCBI chr14:33,807,936...33,822,528
Ensembl chr14:33,807,938...33,822,528
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Aoc1
amine oxidase, copper-containing 1
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AOC1 mRNA]
CTD
PMID:34256052
NCBI chr 6:48,872,189...48,886,122
Ensembl chr 6:48,849,830...48,886,122
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Aoc2
amine oxidase copper containing 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AOC2 mRNA
CTD
PMID:23146750
NCBI chr11:101,214,467...101,220,633
Ensembl chr11:101,215,889...101,220,528
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Aopep
aminopeptidase O
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AOPEP mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr13:63,112,707...63,473,910
Ensembl chr13:63,112,707...63,473,910
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Aox1
aldehyde oxidase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AOX1 mRNA
CTD
PMID:23196670
NCBI chr 1:58,068,963...58,145,569
Ensembl chr 1:58,069,090...58,145,572
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Ap1s1
adaptor protein complex AP-1, sigma 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AP1S1 mRNA
CTD
PMID:23994337
NCBI chr 5:137,063,852...137,074,917
Ensembl chr 5:137,063,847...137,074,989
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Apcs
amyloid P component, serum
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of APCS mRNA
CTD
PMID:19692669
NCBI chr 1:172,721,528...172,722,516
Ensembl chr 1:172,721,528...172,722,608
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Apln
apelin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of APLN mRNA
CTD
PMID:23196670
NCBI chr X:47,114,023...47,123,730
Ensembl chr X:47,114,023...47,123,730
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Aplnr
apelin receptor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of APLNR mRNA
CTD
PMID:32119087
NCBI chr 2:84,966,704...84,970,267
Ensembl chr 2:84,966,569...84,970,267
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Apoa1
apolipoprotein A-I
increases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of APOA1 mRNA 3,3',4,4',5-pentachlorobiphenyl, PCB-126, increases expression of mRNA in rat liver
CTD RGD
PMID:23644946 PMID:23644946
RGD:401794573
NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
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Apoa4
apolipoprotein A-IV
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of APOA4 mRNA
CTD
PMID:20959002
NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757
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Apob
apolipoprotein B
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of APOB mRNA
CTD
PMID:28973532
NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835
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Apoe
apolipoprotein E
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of APOE mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
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Apom
apolipoprotein M
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of APOM mRNA
CTD
PMID:20959002
NCBI chr17:35,347,973...35,350,777
Ensembl chr17:35,347,973...35,351,026
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Aprt
adenine phosphoribosyl transferase
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of APRT mRNA
CTD
PMID:23994337
NCBI chr 8:123,301,376...123,303,646
Ensembl chr 8:123,301,374...123,303,648
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Aptx
aprataxin
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of APTX mRNA
CTD
PMID:23994337
NCBI chr 4:40,682,078...40,703,206
Ensembl chr 4:40,682,382...40,703,194
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Aqp1
aquaporin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AQP1 mRNA
CTD
PMID:23196670
NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540
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Ar
androgen receptor
multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]; [aroclor 1260 co-treated with Chlorodiphenyl (54% Chlorine) co-treated with 2,4,4'-trichlorobiphenyl co-treated with 2,4,2',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,3',4'-tetrachlorobiphenyl] inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]
CTD
PMID:18324785 PMID:21295777 PMID:21357386 PMID:26022396
NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821
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Areg
amphiregulin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AREG mRNA
CTD
PMID:23196670 PMID:29947894
NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
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Arg1
arginase, liver
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ARG1 mRNA
CTD
PMID:23196670
NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382
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Arhgap20
Rho GTPase activating protein 20
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ARHGAP20 mRNA
CTD
PMID:23196670
NCBI chr 9:51,676,651...51,765,158
Ensembl chr 9:51,676,637...51,765,156
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Arhgap29
Rho GTPase activating protein 29
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ARHGAP29 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARHGAP29 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 3:121,746,752...121,810,326
Ensembl chr 3:121,746,190...121,810,402
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Arhgef40
Rho guanine nucleotide exchange factor 40
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARHGEF40 mRNA
CTD
PMID:19692669
NCBI chr14:52,222,158...52,243,704
Ensembl chr14:52,222,176...52,243,708
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Arl4c
ADP-ribosylation factor-like 4C
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARL4C mRNA
CTD
PMID:29947894
NCBI chr 1:88,625,947...88,629,913
Ensembl chr 1:88,600,847...88,629,943
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Arnt
aryl hydrocarbon receptor nuclear translocator
increases expression multiple interactions affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARNT mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARNT mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of ARNT mRNA
CTD
PMID:34256052 PMID:37080397
NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551
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Arnt2
aryl hydrocarbon receptor nuclear translocator 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ARNT2 mRNA
CTD
PMID:23146750
NCBI chr 7:83,895,486...84,059,201
Ensembl chr 7:83,895,486...84,059,384
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Artn
artemin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARTN mRNA
CTD
PMID:32119087
NCBI chr 4:117,783,105...117,787,993
Ensembl chr 4:117,783,359...117,786,960
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As3mt
arsenite methyltransferase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AS3MT mRNA
CTD
PMID:32119087
NCBI chr19:46,695,124...46,729,538
Ensembl chr19:46,695,897...46,729,538
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Asb16
ankyrin repeat and SOCS box-containing 16
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ASB16 mRNA
CTD
PMID:23196670
NCBI chr11:102,159,577...102,170,280
Ensembl chr11:102,159,569...102,170,288
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Ascl5
achaete-scute family bHLH transcription factor 5
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of ASCL5 mRNA
CTD
PMID:30744511
NCBI chr 1:135,978,321...135,979,810
Ensembl chr 1:135,978,542...135,979,108
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Asgr1
asialoglycoprotein receptor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ASGR1 mRNA
CTD
PMID:23196670
NCBI chr11:69,939,735...69,948,721
Ensembl chr11:69,944,911...69,948,720
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Aspg
asparaginase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ASPG mRNA
CTD
PMID:20959002
NCBI chr12:112,073,117...112,094,007
Ensembl chr12:112,073,113...112,093,993
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Atf3
activating transcription factor 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ATF3 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
G
Atf6
activating transcription factor 6
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ATF6 mRNA
CTD
PMID:37080397
NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
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Atg7
autophagy related 7
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ATG7 mRNA
CTD
PMID:37080397
NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575
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Atosb
atos homolog B
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ATOSB mRNA
CTD
PMID:23994337
NCBI chr 4:43,032,414...43,046,220
Ensembl chr 4:43,032,414...43,046,220
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Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ATP1B2 mRNA
CTD
PMID:23196670
NCBI chr11:69,490,554...69,496,786
Ensembl chr11:69,490,562...69,496,768
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Atp1b3
ATPase, Na+/K+ transporting, beta 3 polypeptide
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ATP1B3 mRNA
CTD
PMID:23994337
NCBI chr 9:96,214,708...96,246,368
Ensembl chr 9:96,214,708...96,246,495
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Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Cholecalciferol] results in decreased expression of ATP2B1 mRNA
CTD
PMID:31820026
NCBI chr10:98,750,243...98,862,005
Ensembl chr10:98,750,268...98,862,005
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Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ATP2B4 mRNA
CTD
PMID:23196670
NCBI chr 1:133,630,416...133,728,755
Ensembl chr 1:133,627,195...133,728,779
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Atp2c1
ATPase, Ca++-sequestering
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ATP2C1 mRNA
CTD
PMID:23196670
NCBI chr 9:105,288,561...105,398,456
Ensembl chr 9:105,280,738...105,404,518
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Atp5if1
ATP synthase inhibitory factor subunit 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ATP5IF1 mRNA
CTD
PMID:23196670
NCBI chr 4:132,257,870...132,262,746
Ensembl chr 4:132,257,866...132,260,970
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Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ATP6V0E2 mRNA
CTD
PMID:19692669
NCBI chr 6:48,514,503...48,518,735
Ensembl chr 6:48,514,549...48,518,735
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AU021092
expressed sequence AU021092
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C10H16ORF89 mRNA
CTD
PMID:32119087
NCBI chr16:5,029,677...5,040,170
Ensembl chr16:5,029,687...5,040,163
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Aup1
ancient ubiquitous protein 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AUP1 mRNA
CTD
PMID:23994337
NCBI chr 6:83,031,483...83,034,663
Ensembl chr 6:83,031,502...83,034,789
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Aurka
aurora kinase A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AURKA mRNA
CTD
PMID:23196670
NCBI chr 2:172,198,116...172,212,825
Ensembl chr 2:172,198,110...172,212,455
G
Aurkb
aurora kinase B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AURKB mRNA
CTD
PMID:23196670
NCBI chr11:68,936,477...68,942,490
Ensembl chr11:68,936,473...68,942,490
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Axin2
axin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of AXIN2 mRNA
CTD
PMID:23196670
NCBI chr11:108,808,687...108,841,609
Ensembl chr11:108,811,175...108,841,609
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Axl
AXL receptor tyrosine kinase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AXL mRNA
CTD
PMID:23196670
NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130
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B2m
beta-2 microglobulin
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of B2M mRNA
CTD
PMID:37080397
NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
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B4galnt1
beta-1,4-N-acetyl-galactosaminyl transferase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of B4GALNT1 mRNA
CTD
PMID:20959002
NCBI chr10:127,001,025...127,008,209
Ensembl chr10:127,001,094...127,008,199
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B4galt4
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of B4GALT4 mRNA
CTD
PMID:23196670
NCBI chr16:38,562,600...38,589,416
Ensembl chr16:38,562,626...38,589,411
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Bace2
beta-site APP-cleaving enzyme 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BACE2 mRNA
CTD
PMID:23196670
NCBI chr16:97,157,928...97,244,136
Ensembl chr16:97,157,942...97,244,136
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Bach2
BTB and CNC homology, basic leucine zipper transcription factor 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BACH2 mRNA
CTD
PMID:32119087
NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108
G
Banf1
BAF nuclear assembly factor 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BANF1 mRNA
CTD
PMID:23994337
NCBI chr19:5,414,661...5,416,904
Ensembl chr19:5,414,666...5,417,196
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Bard1
BRCA1 associated RING domain 1
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BARD1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BARD1 mRNA
CTD
PMID:23196670 PMID:29947894
NCBI chr 1:71,066,694...71,142,300
Ensembl chr 1:71,066,657...71,142,305
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Bax
BCL2-associated X protein
affects expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of BAX mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BAX mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BAX protein
CTD
PMID:21703328 PMID:31563530 PMID:37080397
NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
G
Bbof1
basal body orientation factor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BBOF1 mRNA
CTD
PMID:32119087
NCBI chr12:84,455,243...84,488,279
Ensembl chr12:84,455,845...84,489,661
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Bbs2
Bardet-Biedl syndrome 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BBS2 mRNA
CTD
PMID:23196670
NCBI chr 8:94,794,580...94,825,997
Ensembl chr 8:94,794,582...94,825,556
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Bcam
basal cell adhesion molecule
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BCAM mRNA
CTD
PMID:23196670 PMID:29947894
NCBI chr 7:19,490,063...19,504,457
Ensembl chr 7:19,490,056...19,504,941
G
Bcar1
breast cancer anti-estrogen resistance 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BCAR1 mRNA
CTD
PMID:23196670
NCBI chr 8:112,437,106...112,470,481
Ensembl chr 8:112,437,106...112,470,441
G
Bcat1
branched chain aminotransferase 1, cytosolic
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BCAT1 mRNA
CTD
PMID:23196670
NCBI chr 6:144,939,561...145,021,883
Ensembl chr 6:144,939,561...145,021,910
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Bcl2
B cell leukemia/lymphoma 2
multiple interactions decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BCL2 protein
CTD
PMID:20840854 PMID:31563530
NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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Bcl2l11
BCL2 like 11
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BCL2L11 mRNA
CTD
PMID:23196670
NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
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Bdh1
3-hydroxybutyrate dehydrogenase, type 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BDH1 mRNA
CTD
PMID:23196670
NCBI chr16:31,241,115...31,277,719
Ensembl chr16:31,241,098...31,277,719
G
Bex3
brain expressed X-linked 3
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BEX3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BEX3 mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr X:135,171,002...135,172,727
Ensembl chr X:135,171,002...135,172,727
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Bglap
bone gamma carboxyglutamate protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BGLAP protein
CTD
PMID:31820026
NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
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Bhlhe40
basic helix-loop-helix family, member e40
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BHLHE40 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BHLHE40 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 6:108,637,590...108,643,886
Ensembl chr 6:108,637,590...108,643,886
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Bhlhe41
basic helix-loop-helix family, member e41
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BHLHE41 mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr 6:145,803,969...145,811,146
Ensembl chr 6:145,803,969...145,811,284
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Bloc1s2
biogenesis of lysosomal organelles complex-1, subunit 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BLOC1S2 mRNA
CTD
PMID:32119087
NCBI chr19:44,127,685...44,134,909
Ensembl chr19:44,127,685...44,134,885
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Blvrb
biliverdin reductase B
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of BLVRB protein
CTD
PMID:23457121
NCBI chr 7:27,147,403...27,165,406
Ensembl chr 7:27,147,403...27,165,569
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Bmal1
basic helix-loop-helix ARNT like 1
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BMAL1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ARNTL mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333
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Bmp2
bone morphogenetic protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BMP2 mRNA
CTD
PMID:34256052
NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805
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Bmp4
bone morphogenetic protein 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BMP4 mRNA
CTD
PMID:23196670
NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126
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Bmp6
bone morphogenetic protein 6
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BMP6 mRNA
CTD
PMID:23196670
NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
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Bora
bora, aurora kinase A activator
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BORA mRNA
CTD
PMID:23196670
NCBI chr14:99,283,880...99,311,976
Ensembl chr14:99,283,658...99,311,976
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Brca1
breast cancer 1, early onset
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BRCA1 mRNA
CTD
PMID:23196670
NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781
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Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BRINP1 mRNA
CTD
PMID:23196670
NCBI chr 4:68,679,609...68,872,634
Ensembl chr 4:68,679,751...68,872,634
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Btg2
BTG anti-proliferation factor 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of BTG2 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858
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Btnl9
butyrophilin-like 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BTNL9 mRNA
CTD
PMID:32119087
NCBI chr11:49,059,152...49,077,916
Ensembl chr11:49,056,412...49,077,986
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C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C1GALT1 mRNA
CTD
PMID:23196670
NCBI chr 6:7,845,224...7,872,042
Ensembl chr 6:7,844,842...7,875,687
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C1qa
complement component 1, q subcomponent, alpha polypeptide
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C1QA mRNA
CTD
PMID:23146750
NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114
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C1qb
complement component 1, q subcomponent, beta polypeptide
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C1QB mRNA
CTD
PMID:23146750
NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498
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C1qc
complement component 1, q subcomponent, C chain
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of C1QC mRNA
CTD
PMID:23196670
NCBI chr 4:136,617,115...136,620,225
Ensembl chr 4:136,617,115...136,620,376
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C1qtnf5
C1q and tumor necrosis factor related protein 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C1QTNF5 mRNA
CTD
PMID:23146750
NCBI chr 9:44,013,067...44,020,484
Ensembl chr 9:44,018,542...44,020,484
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C1s1
complement component 1, s subcomponent 1
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of C1S mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C1S mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 6:124,507,303...124,519,340
Ensembl chr 6:124,507,304...124,519,318
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C3
complement component 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C3 mRNA
CTD
PMID:23196670
NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
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C4a
complement C4A (Rodgers blood group)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C4A mRNA
CTD
PMID:23196670
NCBI chr17:35,028,069...35,042,436
Ensembl chr17:35,028,069...35,042,440
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Cacnb2
calcium channel, voltage-dependent, beta 2 subunit
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CACNB2 mRNA
CTD
PMID:23196670
NCBI chr 2:14,608,672...14,993,622
Ensembl chr 2:14,607,899...14,992,719
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Cadm1
cell adhesion molecule 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CADM1 mRNA
CTD
PMID:23196670
NCBI chr 9:47,441,468...47,773,578
Ensembl chr 9:47,441,471...47,769,413
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Cadps
Ca2+-dependent secretion activator
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CADPS mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CADPS mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr14:9,646,424...10,097,203
Ensembl chr14:9,646,684...10,097,200
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Cadps2
Ca2+-dependent activator protein for secretion 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CADPS2 mRNA
CTD
PMID:32119087
NCBI chr 6:23,262,765...23,840,662
Ensembl chr 6:23,262,772...23,839,420
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Calcoco1
calcium binding and coiled coil domain 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CALCOCO1 mRNA
CTD
PMID:23196670
NCBI chr15:102,615,212...102,630,616
Ensembl chr15:102,615,212...102,630,613
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Cald1
caldesmon 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CALD1 mRNA
CTD
PMID:23196670
NCBI chr 6:34,575,433...34,752,404
Ensembl chr 6:34,575,435...34,752,408
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Calhm2
calcium homeostasis modulator family member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CALHM2 mRNA
CTD
PMID:23196670
NCBI chr19:47,120,671...47,126,733
Ensembl chr19:47,093,792...47,126,733
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Camk1
calcium/calmodulin-dependent protein kinase I
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CAMK1 mRNA
CTD
PMID:32119087
NCBI chr 6:113,311,085...113,320,883
Ensembl chr 6:113,311,085...113,320,945
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Camk1g
calcium/calmodulin-dependent protein kinase I gamma
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CAMK1G mRNA
CTD
PMID:23196670
NCBI chr 1:193,028,654...193,052,636
Ensembl chr 1:193,028,654...193,052,606
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Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CAMK2N1 mRNA
CTD
PMID:32119087
NCBI chr 4:138,182,459...138,187,437
Ensembl chr 4:138,181,625...138,187,434
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Cap2
cyclase associated actin cytoskeleton regulatory protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CAP2 mRNA
CTD
PMID:20959002
NCBI chr13:46,655,379...46,803,757
Ensembl chr13:46,655,324...46,803,757
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Capn13
calpain 13
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CAPN13 mRNA
CTD
PMID:32119087
NCBI chr17:73,613,451...73,706,376
Ensembl chr17:73,613,459...73,707,861
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Capn8
calpain 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CAPN8 mRNA
CTD
PMID:23196670
NCBI chr 1:182,392,314...182,462,021
Ensembl chr 1:182,392,572...182,459,917
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Car2
carbonic anhydrase 2
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CA2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CA2 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
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Car3
carbonic anhydrase 3
decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CA3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CAR3 mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583
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Car5b
carbonic anhydrase 5b, mitochondrial
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CA5B mRNA
CTD
PMID:23196670
NCBI chr X:162,759,818...162,811,006
Ensembl chr X:162,759,818...162,810,993
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Car8
carbonic anhydrase 8
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CAR8 mRNA
CTD
PMID:20702594
NCBI chr 4:8,141,491...8,239,226
Ensembl chr 4:8,143,362...8,239,041
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Carmil1
capping protein regulator and myosin 1 linker 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CARMIL1 mRNA
CTD
PMID:20702594
NCBI chr13:24,196,464...24,464,983
Ensembl chr13:24,196,327...24,464,778
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Casp12
caspase 12
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of CASP12 mRNA
CTD
PMID:30744511
NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032
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Casp3
caspase 3
increases activity increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CASP3 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CASP3 protein
CTD
PMID:19022367 PMID:31563530
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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Casp8
caspase 8
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CASP8 protein
CTD
PMID:31563530
NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
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Casp9
caspase 9
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CASP9 protein
CTD
PMID:31563530
NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
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Cat
catalase
multiple interactions decreases activity increases expression
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of CAT mRNA; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of CAT protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CAT mRNA
CTD
PMID:24378064 PMID:37080397 PMID:37598416
NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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Cav1
caveolin 1, caveolae protein
multiple interactions decreases expression
EXP ISO
CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 protein]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 protein]; CAV1 gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 gene mutant form promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 protein]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK3 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CAV mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased expression of FYN protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased expression of KEAP1 protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased phosphorylation of PRKCD protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in increased phosphorylation of AKT1 protein]
CTD
PMID:19265715 PMID:20406653 PMID:23196670 PMID:24709675
NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
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Cavin2
caveolae associated 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CAVIN2 mRNA
CTD
PMID:23196670
NCBI chr 1:51,328,285...51,342,119
Ensembl chr 1:51,328,285...51,342,119
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Cavin3
caveolae associated 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CAVIN3 mRNA
CTD
PMID:23196670
NCBI chr 7:105,129,823...105,131,404
Ensembl chr 7:105,129,290...105,131,507
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Cbr1
carbonyl reductase 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CBR1 mRNA
CTD
PMID:20702594
NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393
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Cbr3
carbonyl reductase 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CBR3 mRNA
CTD
PMID:32119087
NCBI chr16:93,480,107...93,487,879
Ensembl chr16:93,480,103...93,487,878
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Cbx7
chromobox 7
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CBX7 mRNA
CTD
PMID:32119087
NCBI chr15:79,800,005...79,855,344
Ensembl chr15:79,800,008...79,855,320
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Cc2d1b
coiled-coil and C2 domain containing 1B
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CC2D1B mRNA
CTD
PMID:20702594
NCBI chr 4:108,477,105...108,495,801
Ensembl chr 4:108,477,137...108,491,320
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Ccdc136
coiled-coil domain containing 136
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CCDC136 mRNA
CTD
PMID:32119087
NCBI chr 6:29,396,296...29,426,954
Ensembl chr 6:29,396,308...29,426,987
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Ccdc80
coiled-coil domain containing 80
decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CCDC80 mRNA
CTD
PMID:23196670 PMID:23994337
NCBI chr16:44,913,770...44,948,287
Ensembl chr16:44,913,765...44,948,440
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Ccdc85b
coiled-coil domain containing 85B
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCDC85B mRNA
CTD
PMID:23994337
NCBI chr19:5,503,191...5,507,591
Ensembl chr19:5,503,208...5,507,922
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Cck
cholecystokinin
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CCK protein alternative form; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Tetrachlorodibenzodioxin co-treated with 2,3,4,7,8-pentachlorodibenzofuran] results in decreased expression of CCK protein alternative form 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CCK protein alternative form
CTD
PMID:10919282
NCBI chr 9:121,318,890...121,324,728
Ensembl chr 9:121,318,890...121,324,760
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Ccl11
C-C motif chemokine ligand 11
multiple interactions
ISO
[AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased expression of CCL11 mRNA
CTD
PMID:34256052
NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
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Ccl19
C-C motif chemokine ligand 19
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL19 mRNA
CTD
PMID:34256052
NCBI chr 4:42,754,525...42,756,558
Ensembl chr 4:42,754,525...42,756,577
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Ccl2
C-C motif chemokine ligand 2
increases expression multiple interactions decreases expression increases secretion
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL2 mRNA]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CCL2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CCL2 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of CCL2 protein; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 protein]; Sunphenon inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CCL2 protein
CTD
PMID:19265715 PMID:19692669 PMID:20959002 PMID:22262711 PMID:23196670 PMID:24378064 PMID:27663891 PMID:28163111 PMID:28351761 PMID:28973532 PMID:30768972 PMID:35618242 PMID:37080397 More...
NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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Ccl20
C-C motif chemokine ligand 20
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL20 mRNA
CTD
PMID:23196670 PMID:28351761
NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
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Ccl22
C-C motif chemokine ligand 22
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL22 mRNA [AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased expression of CCL22 mRNA
CTD
PMID:32119087 PMID:34256052
NCBI chr 8:95,472,312...95,478,016
Ensembl chr 8:95,472,218...95,478,327
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Ccl24
C-C motif chemokine ligand 24
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL24 mRNA
CTD
PMID:32119087 PMID:34256052
NCBI chr 5:135,598,789...135,601,977
Ensembl chr 5:135,598,791...135,601,903
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Ccl3
C-C motif chemokine ligand 3
increases expression multiple interactions increases secretion
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL3 mRNA Sunphenon inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL3 mRNA] 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL3 mRNA]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CCL3 protein]
CTD
PMID:24378064 PMID:30768972
NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
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Ccl4
C-C motif chemokine ligand 4
increases secretion multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CCL4 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL4 mRNA]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CCL4 protein]
CTD
PMID:30768972
NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
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Ccl5
C-C motif chemokine ligand 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL5 mRNA
CTD
PMID:34256052
NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
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Ccn1
cellular communication network factor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCN1 mRNA
CTD
PMID:23196670
NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736
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Ccn2
cellular communication network factor 2
affects expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CCN2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCN2 mRNA
CTD
PMID:20702594 PMID:23196670 PMID:32119087
NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
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Ccna2
cyclin A2
multiple interactions increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with TNF protein] results in increased expression of CCNA2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCNA2 mRNA
CTD
PMID:17557910 PMID:23146750 PMID:23196670
NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
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Ccnb1
cyclin B1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCNB1 mRNA
CTD
PMID:23196670
NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
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Ccnd1
cyclin D1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CCND1 mRNA
CTD
PMID:23196670
NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
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Ccnd2
cyclin D2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCND2 mRNA
CTD
PMID:23196670
NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156
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Ccr1
C-C motif chemokine receptor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCR1 mRNA
CTD
PMID:34256052
NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
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Ccs
copper chaperone for superoxide dismutase
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CCS mRNA
CTD
PMID:20702594
NCBI chr19:4,875,394...4,889,326
Ensembl chr19:4,875,394...4,889,360
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Cd14
CD14 antigen
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD14 mRNA
CTD
PMID:23196670
NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851
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Cd200
CD200 molecule
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD200 mRNA
CTD
PMID:23196670
NCBI chr16:45,202,474...45,229,419
Ensembl chr16:45,202,498...45,229,416
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Cd200r1
CD200 receptor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD200R1 mRNA
CTD
PMID:23196670
NCBI chr16:44,586,141...44,615,341
Ensembl chr16:44,586,099...44,615,341
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Cd24a
CD24a antigen
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD24 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CD24 mRNA
CTD
PMID:20959002 PMID:23196670 PMID:32119087
NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261
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Cd36
CD36 molecule
affects expression increases expression decreases expression multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CD36 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CD36 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD36 mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD36 mRNA] 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CD36 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of CD36 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of CD36 mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CD36 mRNA]
CTD
PMID:20702594 PMID:20959002 PMID:22824115 PMID:23994337 PMID:28163111 PMID:28973532 PMID:29216392 PMID:30312631 More...
NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
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Cd38
CD38 antigen
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD38 mRNA
CTD
PMID:32119087
NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717
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Cd47
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD47 mRNA
CTD
PMID:23196670
NCBI chr16:49,671,691...49,732,799
Ensembl chr16:49,620,896...49,735,373
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Cd55
CD55 molecule, decay accelerating factor for complement
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD55 mRNA
CTD
PMID:23196670
NCBI chr 1:130,357,526...130,390,513
Ensembl chr 1:130,366,764...130,390,481
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Cd74
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CD74 mRNA
CTD
PMID:20959002
NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724
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Cd93
CD93 antigen
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD93 mRNA
CTD
PMID:32119087
NCBI chr 2:148,278,571...148,285,455
Ensembl chr 2:148,278,560...148,285,483
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Cdc14b
CDC14 cell division cycle 14B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDC14B mRNA
CTD
PMID:19692669
NCBI chr13:64,337,085...64,423,670
Ensembl chr13:64,337,082...64,423,104
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Cdc20
cell division cycle 20
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDC20 mRNA
CTD
PMID:23196670
NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549
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Cdca5
cell division cycle associated 5
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CDCA5 mRNA
CTD
PMID:23994337
NCBI chr19:6,135,127...6,141,803
Ensembl chr19:6,135,013...6,141,807
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Cdca8
cell division cycle associated 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDCA8 mRNA
CTD
PMID:23196670
NCBI chr 4:124,812,258...124,830,710
Ensembl chr 4:124,812,258...124,833,104
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Cdh1
cadherin 1
multiple interactions decreases expression
ISO
Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; WP1066 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]
CTD
PMID:28284859
NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
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Cdh17
cadherin 17
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH17 mRNA
CTD
PMID:32119087
NCBI chr 4:11,758,157...11,817,905
Ensembl chr 4:11,758,147...11,817,895
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Cdh2
cadherin 2
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; WP1066 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]
CTD
PMID:28284859
NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303
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Cdh23
cadherin related 23 (otocadherin)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH23 mRNA
CTD
PMID:32119087
NCBI chr10:60,138,527...60,532,291
Ensembl chr10:60,138,527...60,532,269
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Cdk1
cyclin dependent kinase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDK1 mRNA
CTD
PMID:23196670
NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
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Cdk13
cyclin dependent kinase 13
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDK13 mRNA
CTD
PMID:23994337
NCBI chr13:17,885,309...17,979,960
Ensembl chr13:17,884,900...17,979,682
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Cdk2
cyclin dependent kinase 2
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CDK2 mRNA
CTD
PMID:21703328
NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
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Cdkn1a
cyclin dependent kinase inhibitor 1A
decreases expression multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDKN1A protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased expression of CDKN1A protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDKN1A mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDKN1A mRNA
CTD
PMID:20840854 PMID:20959002 PMID:23196670
NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
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Cdon
cell adhesion molecule-related/down-regulated by oncogenes
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDON mRNA
CTD
PMID:23196670
NCBI chr 9:35,332,836...35,418,948
Ensembl chr 9:35,332,424...35,418,948
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Ceacam10
CEA cell adhesion molecule 10
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CEACAM10 mRNA
CTD
PMID:20959002
NCBI chr 7:24,476,592...24,484,081
Ensembl chr 7:24,476,631...24,484,082
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Cebpb
CCAAT/enhancer binding protein beta
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CEBPB mRNA
CTD
PMID:19692669
NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
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Cel
carboxyl ester lipase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CEL mRNA
CTD
PMID:23146750
NCBI chr 2:28,445,831...28,453,415
Ensembl chr 2:28,445,807...28,453,415
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Celf2
CUGBP, Elav-like family member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CELF2 mRNA
CTD
PMID:23196670
NCBI chr 2:6,544,505...7,401,345
Ensembl chr 2:6,544,505...7,514,374
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Celf3
CUGBP, Elav-like family member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CELF3 mRNA
CTD
PMID:32119087
NCBI chr 3:94,385,581...94,405,822
Ensembl chr 3:94,385,602...94,399,505
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Celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CELSR2 mRNA
CTD
PMID:32119087
NCBI chr 3:108,298,164...108,323,416
Ensembl chr 3:108,298,167...108,323,383
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Cenpn
centromere protein N
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CENPN mRNA
CTD
PMID:23196670
NCBI chr 8:117,648,448...117,668,243
Ensembl chr 8:117,648,469...117,668,246
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Cenpx
centromere protein X
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CENPX mRNA
CTD
PMID:23994337
NCBI chr11:120,601,768...120,604,721
Ensembl chr11:120,601,768...120,604,564
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Cep131
centrosomal protein 131
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CEP131 mRNA
CTD
PMID:32119087
NCBI chr11:119,955,247...119,977,684
Ensembl chr11:119,955,256...119,977,653
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Ces1d
carboxylesterase 1D
multiple interactions decreases expression
EXP ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of CES1D protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CES1 mRNA
CTD
PMID:19692669 PMID:23457121
NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
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Ces2c
carboxylesterase 2C
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CES2C mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CES2C mRNA]
CTD
PMID:34256052
NCBI chr 8:105,573,700...105,581,115
Ensembl chr 8:105,573,700...105,581,115
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Ces3b
carboxylesterase 3B
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CES3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CES3 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 8:105,810,365...105,820,561
Ensembl chr 8:105,810,385...105,820,561
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Cetn4
centrin 4
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CETN4 mRNA
CTD
PMID:23994337
NCBI chr 3:37,362,776...37,366,595
Ensembl chr 3:37,361,898...37,366,857
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Cfap95
cilia and flagella associated protein 95
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of CFAP95 mRNA
CTD
PMID:30744511
NCBI chr19:23,536,124...23,630,176
Ensembl chr19:23,536,117...23,630,176
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Cfb
complement factor B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CFB mRNA
CTD
PMID:23196670
NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494
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Chad
chondroadherin
affects expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CHAD mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CHAD mRNA
CTD
PMID:20702594 PMID:32119087
NCBI chr11:94,455,873...94,459,953
Ensembl chr11:94,455,873...94,459,953
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Chek1
checkpoint kinase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CHEK1 mRNA
CTD
PMID:23196670
NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361
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Chka
choline kinase alpha
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CHKA mRNA
CTD
PMID:20959002
NCBI chr19:3,901,585...3,944,368
Ensembl chr19:3,901,773...3,944,369
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Chn2
chimerin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CHN2 mRNA
CTD
PMID:23196670
NCBI chr 6:54,016,917...54,278,797
Ensembl chr 6:54,016,539...54,278,795
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Chpt1
choline phosphotransferase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CHPT1 mRNA
CTD
PMID:23196670
NCBI chr10:88,305,376...88,339,855
Ensembl chr10:88,288,607...88,339,935
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Chst1
carbohydrate sulfotransferase 1
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CHST1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CHST1 mRNA]
CTD
PMID:34256052
NCBI chr 2:92,429,978...92,445,597
Ensembl chr 2:92,430,052...92,445,595
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Chst15
carbohydrate sulfotransferase 15
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CHST15 mRNA
CTD
PMID:23196670
NCBI chr 7:131,837,508...131,919,227
Ensembl chr 7:131,837,509...131,918,957
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Chst3
carbohydrate sulfotransferase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CHST3 mRNA
CTD
PMID:32119087
NCBI chr10:60,017,349...60,057,936
Ensembl chr10:60,017,354...60,055,082
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Cib2
calcium and integrin binding family member 2
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CIB2 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of CIB2 mRNA
CTD
PMID:23196670 PMID:30744511
NCBI chr 9:54,452,074...54,467,512
Ensembl chr 9:54,452,078...54,467,502
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Cidea
cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CIDEA mRNA
CTD
PMID:20959002
NCBI chr18:67,476,634...67,500,864
Ensembl chr18:67,476,674...67,500,855
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Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CITED2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CITED2 mRNA
CTD
PMID:16984957 PMID:19692669 PMID:20959002
NCBI chr10:17,598,452...17,601,422
Ensembl chr10:17,598,966...17,601,422
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Ckm
creatine kinase, muscle
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CKM mRNA
CTD
PMID:32119087
NCBI chr 7:19,145,019...19,155,508
Ensembl chr 7:19,138,701...19,156,766
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Ckmt1
creatine kinase, mitochondrial 1, ubiquitous
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CKMT1 mRNA
CTD
PMID:23196670
NCBI chr 2:121,188,257...121,194,218
Ensembl chr 2:121,188,195...121,194,218
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Clcnka
chloride channel, voltage-sensitive Ka
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CLCNKA mRNA
CTD
PMID:20702594
NCBI chr 4:141,111,922...141,126,017
Ensembl chr 4:141,111,921...141,126,035
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Cldn1
claudin 1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of CLDN1 mRNA
CTD
PMID:30744511
NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591
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Cldnd1
claudin domain containing 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CLDND1 mRNA
CTD
PMID:23196670
NCBI chr16:58,548,269...58,554,610
Ensembl chr16:58,548,273...58,554,614
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Clic3
chloride intracellular channel 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CLIC3 mRNA
CTD
PMID:23196670
NCBI chr 2:25,346,855...25,348,789
Ensembl chr 2:25,346,850...25,348,788
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Clic5
chloride intracellular channel 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CLIC5 mRNA
CTD
PMID:23196670
NCBI chr17:44,445,671...44,591,059
Ensembl chr17:44,445,659...44,591,059
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Cltb
clathrin light chain B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CLTB mRNA
CTD
PMID:23196670
NCBI chr13:54,740,199...54,759,186
Ensembl chr13:54,740,214...54,759,157
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Cltc
clathrin heavy chain
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CLTC mRNA
CTD
PMID:37080397
NCBI chr11:86,585,178...86,648,637
Ensembl chr11:86,585,177...86,648,391
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Clu
clusterin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CLU mRNA
CTD
PMID:32119087
NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996
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Cmbl
carboxymethylenebutenolidase homolog
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CMBL mRNA
CTD
PMID:23196670
NCBI chr15:31,565,314...31,590,266
Ensembl chr15:31,565,535...31,590,265
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Cnksr2
connector enhancer of kinase suppressor of Ras 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CNKSR2 mRNA
CTD
PMID:32119087
NCBI chr X:156,604,426...156,827,454
Ensembl chr X:156,604,432...156,826,290
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Cnksr3
Cnksr family member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CNKSR3 mRNA
CTD
PMID:20959002
NCBI chr10:7,069,061...7,162,237
Ensembl chr10:7,069,063...7,162,237
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Cnpy1
canopy FGF signaling regulator 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CNPY1 mRNA
CTD
PMID:32119087
NCBI chr 5:28,405,817...28,450,786
Ensembl chr 5:28,405,817...28,450,804
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Cnrip1
cannabinoid receptor interacting protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CNRIP1 mRNA
CTD
PMID:23146750
NCBI chr11:17,001,859...17,029,372
Ensembl chr11:17,001,586...17,029,371
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Cntfr
ciliary neurotrophic factor receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CNTFR mRNA
CTD
PMID:23196670
NCBI chr 4:41,657,498...41,697,091
Ensembl chr 4:41,657,498...41,697,089
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Col1a1
collagen, type I, alpha 1
increases expression affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of COL1A1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of COL1A1 mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
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Col3a1
collagen, type III, alpha 1
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of COL3A1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of COL3A1 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866
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Col4a5
collagen, type IV, alpha 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of COL4A5 mRNA
CTD
PMID:19692669
NCBI chr X:140,258,367...140,472,232
Ensembl chr X:140,258,381...140,472,230
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Comt
catechol-O-methyltransferase
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of COMT mRNA
CTD
PMID:30744511
NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
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Coq8a
coenzyme Q8A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of COQ8A mRNA
CTD
PMID:23196670
NCBI chr 1:179,992,803...180,023,585
Ensembl chr 1:179,992,803...180,027,167
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Cp
ceruloplasmin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CP mRNA
CTD
PMID:23196670
NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309
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Cpa1
carboxypeptidase A1, pancreatic
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CPA1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPA1 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 6:30,639,217...30,645,360
Ensembl chr 6:30,639,217...30,645,362
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Cpa2
carboxypeptidase A2, pancreatic
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPA2 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 6:30,541,641...30,564,475
Ensembl chr 6:30,541,581...30,564,475
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Cpeb4
cytoplasmic polyadenylation element binding protein 4
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CPEB4 mRNA
CTD
PMID:20702594
NCBI chr11:31,820,911...31,885,635
Ensembl chr11:31,822,211...31,885,634
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Cped1
cadherin-like and PC-esterase domain containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPED1 mRNA
CTD
PMID:19692669
NCBI chr 6:21,985,875...22,256,406
Ensembl chr 6:21,985,915...22,256,403
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Cpn2
carboxypeptidase N, polypeptide 2
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of CPN2 mRNA
CTD
PMID:30744511
NCBI chr16:30,075,196...30,086,350
Ensembl chr16:30,075,196...30,086,317
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Cpox
coproporphyrinogen oxidase
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CPOX mRNA
CTD
PMID:23994337
NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999
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Cpped1
calcineurin-like phosphoesterase domain containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPPED1 mRNA
CTD
PMID:23196670
NCBI chr16:11,621,546...11,727,377
Ensembl chr16:11,621,585...11,727,309
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Cpq
carboxypeptidase Q
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PGCP mRNA
CTD
PMID:23196670
NCBI chr15:33,083,275...33,594,698
Ensembl chr15:33,083,275...33,594,698
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Cpt1a
carnitine palmitoyltransferase 1a, liver
decreases expression multiple interactions increases expression affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPT1A mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of CPT1A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of CPT1A mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CPT1A mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of CPT1A mRNA
CTD
PMID:23196670 PMID:28163111 PMID:28973532 PMID:30312631 PMID:37080397
NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
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Cpt2
carnitine palmitoyltransferase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPT2 mRNA
CTD
PMID:23196670
NCBI chr 4:107,761,179...107,780,786
Ensembl chr 4:107,761,178...107,780,807
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Cpz
carboxypeptidase Z
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CPZ mRNA
CTD
PMID:23196670
NCBI chr 5:35,659,562...35,682,970
Ensembl chr 5:35,659,562...35,683,042
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Creb1
cAMP responsive element binding protein 1
decreases phosphorylation multiple interactions increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased phosphorylation of CREB1 protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased phosphorylation of and results in decreased activity of CREB1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CREB1 mRNA
CTD
PMID:27509375 PMID:29474705 PMID:37080397
NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
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Creb3l1
cAMP responsive element binding protein 3-like 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CREB3L1 mRNA
CTD
PMID:23196670
NCBI chr 2:91,812,673...91,854,515
Ensembl chr 2:91,812,673...91,854,847
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Creb3l2
cAMP responsive element binding protein 3-like 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CREB3L2 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 6:37,307,956...37,419,083
Ensembl chr 6:37,304,190...37,419,081
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Crem
cAMP responsive element modulator
increases expression decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CREM protein alternative form 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CREM mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CREM mRNA alternative form AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CREM mRNA]
CTD
PMID:16081525 PMID:29474705 PMID:34848246
NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748
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Crip2
cysteine rich protein 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CRIP2 mRNA
CTD
PMID:20959002
NCBI chr12:113,103,856...113,109,126
Ensembl chr12:113,103,856...113,109,126
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Crlf1
cytokine receptor-like factor 1
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CRLF1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CRLF1 mRNA
CTD
PMID:23146750 PMID:32119087
NCBI chr 8:70,945,798...70,956,728
Ensembl chr 8:70,945,808...70,956,731
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Crocc
ciliary rootlet coiled-coil, rootletin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CROCC mRNA
CTD
PMID:32119087
NCBI chr 4:140,743,948...140,787,927
Ensembl chr 4:140,743,948...140,787,861
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Crot
carnitine O-octanoyltransferase
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CROT mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CROT mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr 5:9,016,033...9,047,926
Ensembl chr 5:9,016,033...9,047,324
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Crp
C-reactive protein, pentraxin-related
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CRP mRNA
CTD
PMID:26519613
NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
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Cryl1
crystallin, lambda 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CRYL1 mRNA
CTD
PMID:23196670
NCBI chr14:57,512,491...57,635,940
Ensembl chr14:57,512,450...57,635,986
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Cryzl1
crystallin zeta like 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CRYZL1 mRNA
CTD
PMID:23196670
NCBI chr16:91,486,210...91,525,690
Ensembl chr16:91,486,210...91,525,863
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Csf1
colony stimulating factor 1 (macrophage)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CSF1 mRNA
CTD
PMID:34256052
NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
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Csf3
colony stimulating factor 3 (granulocyte)
increases expression increases secretion
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CSF3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CSF3 protein
CTD
PMID:28351761 PMID:29216392 PMID:35618242
NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
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Csmd2
CUB and Sushi multiple domains 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CSMD2 mRNA
CTD
PMID:32119087
NCBI chr 4:127,880,310...128,461,459
Ensembl chr 4:127,881,650...128,461,449
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Csnk2a1
casein kinase 2, alpha 1 polypeptide
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CSNK2A1 mRNA
CTD
PMID:21703328
NCBI chr 2:152,068,468...152,123,772
Ensembl chr 2:152,068,759...152,123,772
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Csrp2
cysteine and glycine-rich protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CSRP2 mRNA
CTD
PMID:20959002
NCBI chr10:110,756,037...110,775,375
Ensembl chr10:110,755,650...110,775,483
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Ctnnd1
catenin delta 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CTNND1 mRNA
CTD
PMID:23146750
NCBI chr 2:84,417,440...84,489,321
Ensembl chr 2:84,430,415...84,481,109 Ensembl chr 2:84,430,415...84,481,109
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Ctsl
cathepsin L
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CTSL mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704
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Cubn
cubilin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CUBN mRNA
CTD
PMID:32119087
NCBI chr 2:13,281,149...13,496,687
Ensembl chr 2:13,281,149...13,496,624
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Cux2
cut-like homeobox 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CUX2 mRNA
CTD
PMID:19692669
NCBI chr 5:121,996,025...122,188,522
Ensembl chr 5:121,994,429...122,188,165
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Cx3cl1
C-X3-C motif chemokine ligand 1
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CX3CL1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CX3CL1 mRNA
CTD
PMID:19692669 PMID:23196670 PMID:28351761
NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055
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Cx3cr1
C-X3-C motif chemokine receptor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CX3CR1 mRNA
CTD
PMID:34256052
NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,877,749...119,898,945
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Cxcl1
C-X-C motif chemokine ligand 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL1 mRNA
CTD
PMID:28351761 PMID:35618242
NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
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Cxcl10
C-X-C motif chemokine ligand 10
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CXCL10 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL10 mRNA
CTD
PMID:23146750 PMID:28351761 PMID:35618242
NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
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Cxcl11
chemokine (C-X-C motif) ligand 11
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL11 mRNA
CTD
PMID:28351761
NCBI chr 5:92,507,403...92,511,155
Ensembl chr 5:92,507,403...92,513,344
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Cxcl12
C-X-C motif chemokine ligand 12
decreases expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CXCL12 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL12 mRNA
CTD
PMID:23994337 PMID:34256052
NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328
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Cxcl13
C-X-C motif chemokine ligand 13
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CXCL13 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CXCL13 mRNA
CTD
PMID:16984957 PMID:23196670
NCBI chr 5:96,104,785...96,108,927
Ensembl chr 5:96,104,810...96,108,927
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Cxcl14
C-X-C motif chemokine ligand 14
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CXCL14 mRNA
CTD
PMID:20959002
NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364
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Cxcl15
C-X-C motif chemokine ligand 15
increases expression increases secretion multiple interactions decreases expression decreases secretion
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL8 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CXCL8 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CXCL8 protein]; 3',4'-dimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of CXCL8 protein]; 3',4'-dimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CXCL8 protein]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CXCL8 protein]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL8 mRNA]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of CXCL8 protein]; lipoxin A4 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CXCL8 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CXCL8 mRNA
CTD
PMID:22262711 PMID:25433332 PMID:27663891 PMID:28351761 PMID:30768972 PMID:35618242 More...
NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL2 mRNA
CTD
PMID:28351761
NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
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Cxcl3
C-X-C motif chemokine ligand 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL1 mRNA
CTD
PMID:28351761 PMID:35618242
NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
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Cxcr5
C-X-C motif chemokine receptor 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCR5 mRNA
CTD
PMID:34256052
NCBI chr 9:44,423,084...44,437,741
Ensembl chr 9:44,423,084...44,473,174
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Cyb5r1
cytochrome b5 reductase 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of CYB5R1 mRNA
CTD
PMID:37080397
NCBI chr 1:134,333,519...134,339,476
Ensembl chr 1:134,333,297...134,339,478
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Cybb
cytochrome b-245, beta polypeptide
multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [NCF1 protein binds to CYBB protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [NCF1 protein modified form binds to CYBB protein]
CTD
PMID:20299304
NCBI chr X:9,301,493...9,354,005
Ensembl chr X:9,301,491...9,354,010
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Cybrd1
cytochrome b reductase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYBRD1 mRNA
CTD
PMID:23196670
NCBI chr 2:70,948,398...70,973,270
Ensembl chr 2:70,948,267...70,973,270
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Cyfip2
cytoplasmic FMR1 interacting protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYFIP2 mRNA
CTD
PMID:20959002
NCBI chr11:46,084,676...46,203,686
Ensembl chr11:46,084,677...46,203,686
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Cygb
cytoglobin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYGB mRNA
CTD
PMID:32119087
NCBI chr11:116,536,421...116,544,887
Ensembl chr11:116,536,421...116,545,139
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Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP11A1 mRNA
CTD
PMID:12781204
NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
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Cyp11b2
cytochrome P450, family 11, subfamily b, polypeptide 2
multiple interactions increases activity increases expression
ISO
3',4'-dimethoxyflavone promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP11B2 mRNA]; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP11B2 mRNA; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of CYP11B2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP11B2 protein
CTD
PMID:14962509 PMID:15703266 PMID:16216300 PMID:16396990 PMID:20574914 PMID:25765474 More...
NCBI chr15:74,722,467...74,728,080
Ensembl chr15:74,722,859...74,728,167
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
decreases activity increases expression decreases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of CYP17A1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP17A1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP17A1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP17A1 mRNA]
CTD
PMID:12781204 PMID:15703266 PMID:16216300 PMID:20959002 PMID:34256052
NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611
G
Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP19A1 mRNA [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP19A1 mRNA; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of CYP19A1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP19A1 mRNA]
CTD
PMID:16216300 PMID:20574914 PMID:22262711 PMID:25765474 PMID:34256052
NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions increases activity increases expression affects expression increases expression
ISO EXP
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of and results in increased activity of CYP1A1 protein; 6,2',4'-trimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; 6,2',4'-trimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Benzo(a)pyrene] results in increased activity of CYP1A1 protein; [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [6,2',4'-trimethoxyflavone binds to and results in decreased activity of AHR protein] inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP1A1 mRNA; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of CYP1A1 mRNA; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [[3,4,5,3',4'-pentachlorobiphenyl co-treated with Benzo(a)pyrene] results in increased activity of CYP1A1 protein]; Decitabine promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Estradiol promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Fulvestrant promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Oxygen deficiency inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Oxygen deficiency inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; trichostatin A promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA] 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [Chlorodiphenyl (54% Chlorine) co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of CYP1A1 mRNA 3,4,5,3',4'-pentachlorobiphenyl analog results in increased expression of CYP1A1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A1 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] results in increased activity of CYP1A1 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased activity of CYP1A1 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP1A1 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of CYP1A1 mRNA; [Tetrachlorodibenzodioxin co-treated with 2,3,4,7,8-pentachlorodibenzofuran co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A1 protein; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Selenic Acid deficiency promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; Selenic Acid promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of CYP1A1 mRNA 3,3',4,4',5-pentachlorobiphenyl, PCB-126, increases expression of mRNA in rat liver
CTD RGD
PMID:10986007 PMID:11752103 PMID:12628580 PMID:12781204 PMID:15041469 PMID:15223772 PMID:15352264 PMID:15371557 PMID:15659568 PMID:15908097 PMID:15919853 PMID:15990133 PMID:16049271 PMID:16081525 PMID:16107549 PMID:16339789 PMID:16396990 PMID:16489053 PMID:16628245 PMID:16750337 PMID:16835634 PMID:16983182 PMID:17160104 PMID:17324954 PMID:17342195 PMID:17342196 PMID:17627975 PMID:18042819 PMID:19043309 PMID:19144771 PMID:19447902 PMID:19553035 PMID:19692669 PMID:20570689 PMID:20702594 PMID:20819910 PMID:20959002 PMID:21292640 PMID:21335049 PMID:21513769 PMID:21561885 PMID:21781905 PMID:21865291 PMID:22266287 PMID:23146750 PMID:23196670 PMID:23457121 PMID:23644946 PMID:23674508 PMID:23994337 PMID:24355420 PMID:24378064 PMID:24472611 PMID:25068733 PMID:25116688 PMID:25304490 PMID:25433332 PMID:25530946 PMID:25654323 PMID:25668756 PMID:25765474 PMID:26006071 PMID:26396156 PMID:26410179 PMID:26967026 PMID:27055685 PMID:28284859 PMID:28351761 PMID:29738842 PMID:29947894 PMID:30744511 PMID:30768972 PMID:30991879 PMID:31563530 PMID:32119087 PMID:33026256 PMID:34256052 PMID:34848246 PMID:35618242 PMID:37080397 PMID:23644946 More...
RGD:401794573
NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
decreases activity multiple interactions increases activity increases expression decreases response to substance affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of CYP1A2 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]; [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP1A2 mRNA; [AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]; [aroclor 1260 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of CYP1A2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of CYP1A2 mRNA; [MT1 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which affects the expression of CYP1A2 mRNA; [MT2 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which affects the expression of CYP1A2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP1A2 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [CYP1A2 protein results in decreased methylation of 7-methoxyresorufin]; [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A2 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] results in increased activity of CYP1A2 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased activity of CYP1A2 protein; [Tetrachlorodibenzodioxin co-treated with 2,3,4,7,8-pentachlorodibenzofuran co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A2 protein; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA] 3,4,5,3',4'-pentachlorobiphenyl analog results in increased expression of CYP1A2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 protein CYP1A2 results in decreased susceptibility to 3,4,5,3',4'-pentachlorobiphenyl 3,4,5,3',4'-pentachlorobiphenyl affects the expression of CYP1A2 mRNA
CTD
PMID:10986007 PMID:12635099 PMID:15659567 PMID:16049271 PMID:16628245 PMID:16835634 PMID:17160104 PMID:17342195 PMID:17342196 PMID:19692669 PMID:20702594 PMID:20959002 PMID:20961953 PMID:21335049 PMID:21571617 PMID:23674508 PMID:25068733 PMID:25530946 PMID:26770886 PMID:28163111 PMID:28973532 PMID:30312631 PMID:31563530 PMID:34256052 PMID:36372259 More...
NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
multiple interactions affects expression decreases expression increases expression
ISO EXP
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; TNF protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 protein] 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Cholecalciferol] results in increased expression of CYP1B1 mRNA; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; Estradiol promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]; Fulvestrant promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of CYP1B1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP1B1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 protein Sunphenon promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]
CTD
PMID:15041469 PMID:15908097 PMID:15990133 PMID:17557910 PMID:19358281 PMID:19692669 PMID:20959002 PMID:21513769 PMID:21703328 PMID:22262711 PMID:23146750 PMID:23196670 PMID:24378064 PMID:25530946 PMID:25654323 PMID:29738842 PMID:31563530 PMID:31820026 PMID:32119087 PMID:34256052 PMID:35618242 PMID:37080397 More...
NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
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Cyp21a1
cytochrome P450, family 21, subfamily a, polypeptide 1
increases activity increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP21A2 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP21A2 mRNA
CTD
PMID:15703266 PMID:16216300
NCBI chr17:35,020,322...35,023,400
Ensembl chr17:35,020,322...35,023,535
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Cyp24a1
cytochrome P450, family 24, subfamily a, polypeptide 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP24A1 mRNA
CTD
PMID:31820026
NCBI chr 2:170,324,877...170,339,065
Ensembl chr 2:170,324,628...170,339,065
G
Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP27B1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP27B1 mRNA]
CTD
PMID:31820026 PMID:34256052
NCBI chr10:126,884,115...126,891,897
Ensembl chr10:126,884,119...126,888,875
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Cyp2a22
cytochrome P450, family 2, subfamily a, polypeptide 22
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2A1 mRNA
CTD
PMID:19692669
NCBI chr 7:26,631,564...26,638,838
Ensembl chr 7:26,631,056...26,638,809
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Cyp2b10
cytochrome P450, family 2, subfamily b, polypeptide 10
increases expression multiple interactions decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2B6 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2B10 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [aroclor 1260 results in increased expression of CYP2B10 mRNA]; aroclor 1260 promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2B10 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2B3 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2B3 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP2B3 mRNA
CTD
PMID:19692669 PMID:30312631 PMID:34256052
NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
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Cyp2b13
cytochrome P450, family 2, subfamily b, polypeptide 13
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP2B2 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CYP2B2 mRNA
CTD
PMID:20959002 PMID:25530946
NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622
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Cyp2c29
cytochrome P450, family 2, subfamily c, polypeptide 29
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2C6 mRNA]
CTD
PMID:34256052
NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
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Cyp2c38
cytochrome P450, family 2, subfamily c, polypeptide 38
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2C19 mRNA
CTD
PMID:19692669
NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
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Cyp2c52-ps
cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP2C11 mRNA
CTD
PMID:31820026
NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
decreases expression increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP2E1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2E1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2E1 mRNA]
CTD
PMID:19692669 PMID:23196670 PMID:28673560 PMID:34256052
NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
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Cyp2f2
cytochrome P450, family 2, subfamily f, polypeptide 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP2F2 mRNA
CTD
PMID:20959002
NCBI chr 7:26,819,380...26,833,085
Ensembl chr 7:26,819,334...26,833,085
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Cyp2j9
cytochrome P450, family 2, subfamily j, polypeptide 9
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CYP2J9 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP2J9 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815
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Cyp2s1
cytochrome P450, family 2, subfamily s, polypeptide 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP2S1 mRNA
CTD
PMID:23994337
NCBI chr 7:25,501,894...25,515,950
Ensembl chr 7:25,501,900...25,516,338
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Cyp3a11
cytochrome P450, family 3, subfamily a, polypeptide 11
multiple interactions affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of CYP3A11 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of CYP3A11 mRNA
CTD
PMID:30312631 PMID:37080397
NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
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Cyp3a13
cytochrome P450, family 3, subfamily a, polypeptide 13
decreases expression multiple interactions affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP3A13 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CYP3A13 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of CYP3A7 mRNA
CTD
PMID:16984957 PMID:20959002 PMID:21703328
NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
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Cyp4a10
cytochrome P450, family 4, subfamily a, polypeptide 10
increases expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP4A10 mRNA aroclor 1260 promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP4A10 mRNA]
CTD
PMID:30312631
NCBI chr 4:115,375,484...115,390,846
Ensembl chr 4:115,375,461...115,390,846
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Cyp4a14
cytochrome P450, family 4, subfamily a, polypeptide 14
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP4A14 mRNA
CTD
PMID:17627975 PMID:21335049
NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339
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Cyp4b1
cytochrome P450, family 4, subfamily b, polypeptide 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP4B1 mRNA
CTD
PMID:23196670
NCBI chr 4:115,481,895...115,504,918
Ensembl chr 4:115,481,922...115,504,920
G
Cyp51
cytochrome P450, family 51
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP51 mRNA
CTD
PMID:23196670
NCBI chr 5:4,130,674...4,154,697
Ensembl chr 5:4,131,145...4,154,746
G
Cyp7a1
cytochrome P450, family 7, subfamily a, polypeptide 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP7A1 mRNA
CTD
PMID:23146750
NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
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Cytip
cytohesin 1 interacting protein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYTIP mRNA
CTD
PMID:23196670
NCBI chr 2:58,019,151...58,085,559
Ensembl chr 2:58,019,149...58,085,544
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Dact2
dishevelled-binding antagonist of beta-catenin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DACT2 mRNA
CTD
PMID:20959002
NCBI chr17:14,415,492...14,424,595
Ensembl chr17:14,415,314...14,424,566
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Dao
D-amino acid oxidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DAO mRNA
CTD
PMID:20959002
NCBI chr 5:114,137,696...114,163,736
Ensembl chr 5:114,141,764...114,163,743
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Dbp
D site albumin promoter binding protein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DBP mRNA
CTD
PMID:32119087
NCBI chr 7:45,354,658...45,359,579
Ensembl chr 7:45,354,512...45,359,627
G
Dcaf12l1
DDB1 and CUL4 associated factor 12-like 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DCAF12L1 mRNA
CTD
PMID:32119087
NCBI chr X:43,875,444...43,879,074
Ensembl chr X:43,875,447...43,879,074
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Dcbld2
discoidin, CUB and LCCL domain containing 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DCBLD2 mRNA
CTD
PMID:23196670
NCBI chr16:58,228,789...58,304,013
Ensembl chr16:58,228,806...58,290,090
G
Dclk1
doublecortin-like kinase 1
increases expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DCLK1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DCLK1 mRNA
CTD
PMID:23196670 PMID:23994337
NCBI chr 3:55,149,724...55,446,489
Ensembl chr 3:55,149,785...55,446,489
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Dcn
decorin
increases expression decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DCN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DCN mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005
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Ddc
dopa decarboxylase
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DDC mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DDC mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr11:11,764,101...11,848,144
Ensembl chr11:11,764,101...11,848,144
G
Ddit3
DNA-damage inducible transcript 3
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of DDIT3 mRNA
CTD
PMID:37080397
NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157 Ensembl chr10:127,126,643...127,132,157
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Ddx39a
DEAD box helicase 39a
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DDX39A mRNA
CTD
PMID:23196670
NCBI chr 8:84,441,806...84,453,533
Ensembl chr 8:84,441,806...84,453,521
G
Defb1
defensin beta 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DEFB1 mRNA
CTD
PMID:20959002
NCBI chr 8:22,266,571...22,285,201
Ensembl chr 8:22,266,615...22,285,201
G
Defb19
defensin beta 19
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DEFB24 mRNA
CTD
PMID:32119087
NCBI chr 2:152,418,006...152,422,232
Ensembl chr 2:152,418,006...152,422,232
G
Deptor
DEP domain containing MTOR-interacting protein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DEPTOR mRNA
CTD
PMID:29947894
NCBI chr15:54,975,824...55,122,667
Ensembl chr15:54,975,713...55,122,667
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Des
desmin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DES mRNA
CTD
PMID:23196670
NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223
G
Dgat2
diacylglycerol O-acyltransferase 2
multiple interactions increases expression
EXP ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of DGAT2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DGAT2 protein
CTD
PMID:26693162 PMID:28973532
NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926
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Dgkg
diacylglycerol kinase, gamma
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DGKG mRNA
CTD
PMID:35618242
NCBI chr16:22,285,318...22,476,051
Ensembl chr16:22,287,211...22,475,971
G
Dgkz
diacylglycerol kinase zeta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DGKZ mRNA
CTD
PMID:32119087
NCBI chr 2:91,763,167...91,806,788
Ensembl chr 2:91,763,169...91,806,209
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Dhcr7
7-dehydrocholesterol reductase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DHCR7 mRNA
CTD
PMID:23196670
NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147
G
Dhh
desert hedgehog
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DHH mRNA
CTD
PMID:32119087
NCBI chr15:98,779,496...98,796,443
Ensembl chr15:98,789,033...98,796,421
G
Dhrs9
dehydrogenase/reductase 9
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of DHRS9 mRNA
CTD
PMID:21703328
NCBI chr 2:69,210,806...69,233,430
Ensembl chr 2:69,210,789...69,234,877
G
Dio1
deiodinase, iodothyronine, type I
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DIO1 mRNA
CTD
PMID:20959002
NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366
G
Dipk1a
divergent protein kinase domain 1A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DIPK1A mRNA
CTD
PMID:19692669
NCBI chr 5:108,055,908...108,134,943
Ensembl chr 5:108,055,919...108,134,951
G
Disp1
dispatched RND transporter family member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DISP1 mRNA
CTD
PMID:32119087
NCBI chr 1:182,867,828...183,010,257
Ensembl chr 1:182,867,830...183,003,086
G
Dkk1
dickkopf WNT signaling pathway inhibitor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DKK1 mRNA
CTD
PMID:35618242
NCBI chr19:30,523,276...30,526,896
Ensembl chr19:30,523,263...30,527,065
G
Dlat
dihydrolipoamide S-acetyltransferase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DLAT mRNA
CTD
PMID:20959002
NCBI chr 9:50,545,933...50,571,080
Ensembl chr 9:50,545,933...50,571,080
G
Dlg4
discs large MAGUK scaffold protein 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DLG4 mRNA
CTD
PMID:23196670
NCBI chr11:69,908,029...69,938,107
Ensembl chr11:69,907,768...69,938,348
G
Dlgap4
DLG associated protein 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DLGAP4 mRNA
CTD
PMID:32119087
NCBI chr 2:156,455,431...156,606,283
Ensembl chr 2:156,455,625...156,606,283
G
Dlk1
delta like non-canonical Notch ligand 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DLK1 mRNA
CTD
PMID:23196670
NCBI chr12:109,418,411...109,429,262
Ensembl chr12:109,418,749...109,429,262
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Dmbt1
deleted in malignant brain tumors 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DMBT1 mRNA
CTD
PMID:23196670
NCBI chr 7:130,633,787...130,723,357
Ensembl chr 7:130,633,776...130,723,357
G
Dmd
dystrophin, muscular dystrophy
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DMD mRNA
CTD
PMID:23196670
NCBI chr X:81,858,244...84,248,656
Ensembl chr X:81,992,476...84,249,747
G
Dnajb11
DnaJ heat shock protein family (Hsp40) member B11
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DNAJB11 mRNA
CTD
PMID:23994337
NCBI chr16:22,676,595...22,698,384
Ensembl chr16:22,676,595...22,698,384
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Dnm1
dynamin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DNM1 mRNA
CTD
PMID:23196670
NCBI chr 2:32,198,483...32,243,361
Ensembl chr 2:32,198,483...32,243,350
G
Dnmt1
DNA methyltransferase 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of DNMT1 mRNA
CTD
PMID:37080397
NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
G
Dnmt3a
DNA methyltransferase 3A
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of DNMT3A mRNA
CTD
PMID:37080397
NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443
G
Dnmt3b
DNA methyltransferase 3B
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of DNMT3B mRNA
CTD
PMID:37080397
NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650
G
Dock7
dedicator of cytokinesis 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DOCK7 mRNA
CTD
PMID:23146750
NCBI chr 4:98,824,669...99,019,190
Ensembl chr 4:98,824,908...99,009,152
G
Donson
downstream neighbor of SON
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DONSON mRNA
CTD
PMID:23196670
NCBI chr16:91,463,744...91,485,702
Ensembl chr16:91,473,696...91,485,658
G
Dpep1
dipeptidase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DPEP1 mRNA
CTD
PMID:23196670
NCBI chr 8:123,913,069...123,928,551
Ensembl chr 8:123,912,981...123,928,551
G
Dpep2
dipeptidase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DPEP2 mRNA
CTD
PMID:23196670
NCBI chr 8:106,711,577...106,732,658
Ensembl chr 8:106,711,576...106,718,391 Ensembl chr 8:106,711,576...106,718,391
G
Dpm2
dolichyl-phosphate mannosyltransferase subunit 2, regulatory
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DPM2 mRNA
CTD
PMID:19692669
NCBI chr 2:32,460,870...32,463,583
Ensembl chr 2:32,460,870...32,463,591
G
Dpp4
dipeptidylpeptidase 4
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DPP4 mRNA
CTD
PMID:37080397
NCBI chr 2:62,160,417...62,242,635
Ensembl chr 2:62,160,417...62,242,575
G
Dpysl3
dihydropyrimidinase-like 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DPYSL3 mRNA
CTD
PMID:23196670
NCBI chr18:43,454,044...43,571,354
Ensembl chr18:43,454,049...43,571,351
G
Dtnb
dystrobrevin, beta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DTNB mRNA
CTD
PMID:23196670
NCBI chr12:3,622,372...3,834,070
Ensembl chr12:3,622,381...3,831,796
G
Dusp1
dual specificity phosphatase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DUSP1 mRNA
CTD
PMID:23196670
NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
G
Dusp18
dual specificity phosphatase 18
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DUSP18 mRNA
CTD
PMID:23196670
NCBI chr11:3,844,940...3,851,299
Ensembl chr11:3,845,240...3,851,296
G
Dusp6
dual specificity phosphatase 6
multiple interactions increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of DUSP6 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DUSP6 mRNA
CTD
PMID:16984957 PMID:23196670
NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351
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Dusp9
dual specificity phosphatase 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DUSP9 mRNA
CTD
PMID:23146750
NCBI chr X:72,682,995...72,687,120
Ensembl chr X:72,683,025...72,687,120
G
Dysf
dysferlin
affects expression increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of DYSF mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DYSF mRNA
CTD
PMID:20702594 PMID:23994337
NCBI chr 6:83,985,344...84,188,042
Ensembl chr 6:83,985,572...84,188,042
G
E2f4
E2F transcription factor 4
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of E2F4 mRNA
CTD
PMID:21703328
NCBI chr 8:106,024,295...106,032,002
Ensembl chr 8:106,024,295...106,032,002
G
Eaf2
ELL associated factor 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EAF2 mRNA
CTD
PMID:23196670
NCBI chr16:36,613,246...36,695,275
Ensembl chr16:36,613,246...36,695,365
G
Ears2
glutamyl-tRNA synthetase 2, mitochondrial
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EARS2 mRNA
CTD
PMID:32119087
NCBI chr 7:121,633,385...121,666,436
Ensembl chr 7:121,636,436...121,666,486
G
Ech1
enoyl coenzyme A hydratase 1, peroxisomal
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ECH1 mRNA
CTD
PMID:23196670
NCBI chr 7:28,524,763...28,531,664
Ensembl chr 7:28,524,642...28,531,672
G
Ecm1
extracellular matrix protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ECM1 mRNA
CTD
PMID:23196670
NCBI chr 3:95,641,459...95,646,880
Ensembl chr 3:95,641,459...95,646,881
G
Edn1
endothelin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EDN1 mRNA
CTD
PMID:23196670
NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
G
Eef2
eukaryotic translation elongation factor 2
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of EEF2 mRNA
CTD
PMID:37080397
NCBI chr10:81,012,465...81,018,343
Ensembl chr10:81,012,465...81,018,332
G
Eef2k
eukaryotic elongation factor-2 kinase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EEF2K mRNA
CTD
PMID:32119087
NCBI chr 7:120,442,080...120,506,441
Ensembl chr 7:120,442,054...120,506,673
G
Eepd1
endonuclease/exonuclease/phosphatase family domain containing 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EEPD1 mRNA
CTD
PMID:23196670
NCBI chr 9:25,392,809...25,515,406
Ensembl chr 9:25,392,843...25,515,406
G
Efcab11
EF-hand calcium binding domain 11
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EFCAB11 mRNA
CTD
PMID:23196670
NCBI chr12:99,683,790...99,849,701
Ensembl chr12:99,659,304...99,850,698
G
Efcc1
EF hand and coiled-coil domain containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EFCC1 mRNA
CTD
PMID:23146750
NCBI chr 6:87,707,577...87,739,410
Ensembl chr 6:87,707,851...87,732,890
G
Efnb1
ephrin B1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EFNB1 mRNA
CTD
PMID:23196670
NCBI chr X:98,179,667...98,192,628
Ensembl chr X:98,179,736...98,192,597
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Egf
epidermal growth factor
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EGF mRNA 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein binds to EGFR protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]
CTD
PMID:20959002 PMID:29329451
NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
G
Egflam
EGF-like, fibronectin type III and laminin G domains
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EGFLAM mRNA
CTD
PMID:32119087
NCBI chr15:7,235,598...7,428,203
Ensembl chr15:7,235,601...7,427,876
G
Egfr
epidermal growth factor receptor
affects binding multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl binds to EGFR protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein binds to EGFR protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]
CTD
PMID:29329451
NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
G
Egr1
early growth response 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EGR1 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
G
Ehbp1
EH domain binding protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EHBP1 mRNA
CTD
PMID:20959002
NCBI chr11:21,955,825...22,237,086
Ensembl chr11:21,955,828...22,292,292
G
Ehd3
EH-domain containing 3
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of EHD3 mRNA
CTD
PMID:20702594
NCBI chr17:74,111,836...74,139,088
Ensembl chr17:74,111,129...74,139,089
G
Eif1ax
eukaryotic translation initiation factor 1A, X-linked
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of EIF1AX mRNA
CTD
PMID:21703328
NCBI chr X:158,155,174...158,172,617
Ensembl chr X:158,155,174...158,172,924
G
Eif3f
eukaryotic translation initiation factor 3, subunit F
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of EIF3F mRNA
CTD
PMID:37080397
NCBI chr 7:108,533,622...108,541,149
Ensembl chr 7:108,533,624...108,542,158
G
Eln
elastin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ELN mRNA
CTD
PMID:32119087
NCBI chr 5:134,731,449...134,776,300
Ensembl chr 5:134,731,447...134,776,177
G
Elovl5
ELOVL fatty acid elongase 5
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ELOVL5 mRNA
CTD
PMID:20702594
NCBI chr 9:77,824,647...77,891,801
Ensembl chr 9:77,824,646...77,891,801
G
Elovl6
ELOVL fatty acid elongase 6
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ELOVL6 mRNA
CTD
PMID:23196670
NCBI chr 3:129,326,035...129,432,144
Ensembl chr 3:129,326,004...129,432,144
G
Emp1
epithelial membrane protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EMP1 mRNA
CTD
PMID:23196670
NCBI chr 6:135,339,548...135,360,171
Ensembl chr 6:135,339,543...135,360,171
G
Emp2
epithelial membrane protein 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EMP2 mRNA
CTD
PMID:23196670
NCBI chr16:10,099,613...10,131,832
Ensembl chr16:10,099,613...10,131,832
G
Enah
ENAH actin regulator
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ENAH mRNA
CTD
PMID:23196670
NCBI chr 1:181,723,949...181,848,132
Ensembl chr 1:181,723,949...181,847,555
G
Enc1
ectodermal-neural cortex 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ENC1 mRNA
CTD
PMID:32119087
NCBI chr13:97,377,613...97,389,548
Ensembl chr13:97,377,613...97,389,542
G
Eno3
enolase 3, beta muscle
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ENO3 mRNA
CTD
PMID:23196670
NCBI chr11:70,543,973...70,553,339
Ensembl chr11:70,548,028...70,553,339
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Enpep
glutamyl aminopeptidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ENPEP mRNA
CTD
PMID:20959002
NCBI chr 3:129,062,826...129,126,398
Ensembl chr 3:129,062,824...129,126,369
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Enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ENPP1 mRNA
CTD
PMID:23196670
NCBI chr10:24,513,812...24,588,057
Ensembl chr10:24,513,812...24,588,057
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Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ENPP2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ENPP2 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288
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Enpp3
ectonucleotide pyrophosphatase/phosphodiesterase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ENPP3 mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr10:24,649,712...24,712,093
Ensembl chr10:24,648,304...24,718,721
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Entpd3
ectonucleoside triphosphate diphosphohydrolase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ENTPD3 mRNA
CTD
PMID:23196670
NCBI chr 9:120,368,884...120,397,393
Ensembl chr 9:120,368,884...120,397,393
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Epas1
endothelial PAS domain protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EPAS1 mRNA
CTD
PMID:23196670
NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838
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Epb41l1
erythrocyte membrane protein band 4.1 like 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EPB41L1 mRNA
CTD
PMID:23196670
NCBI chr 2:156,255,918...156,385,134
Ensembl chr 2:156,262,829...156,385,134
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Epcam
epithelial cell adhesion molecule
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EPCAM mRNA
CTD
PMID:20959002
NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557
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Epha7
Eph receptor A7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EPHA7 mRNA
CTD
PMID:23196670
NCBI chr 4:28,811,840...28,969,391
Ensembl chr 4:28,813,131...28,967,499
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Ephb1
Eph receptor B1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EPHB1 mRNA
CTD
PMID:32119087
NCBI chr 9:101,799,327...102,231,892
Ensembl chr 9:101,799,327...102,231,892
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Ephx1
epoxide hydrolase 1, microsomal
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EPHX1 mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
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Ephx2
epoxide hydrolase 2, cytoplasmic
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EPHX2 mRNA
CTD
PMID:23196670
NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
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Eps8
epidermal growth factor receptor pathway substrate 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EPS8 mRNA
CTD
PMID:32119087
NCBI chr 6:137,454,242...137,626,262
Ensembl chr 6:137,454,243...137,631,874
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Ereg
epiregulin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EREG mRNA
CTD
PMID:35618242
NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
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Ero1a
endoplasmic reticulum oxidoreductase 1 alpha
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ERO1A mRNA
CTD
PMID:23196670
NCBI chr14:45,520,544...45,556,029
Ensembl chr14:45,520,544...45,556,228
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Esm1
endothelial cell-specific molecule 1
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ESM1 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of ESM1 mRNA
CTD
PMID:20959002 PMID:30744511
NCBI chr13:113,346,193...113,354,638
Ensembl chr13:113,346,193...113,354,632
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Esr1
estrogen receptor 1 (alpha)
affects binding multiple interactions affects expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl binds to ESR1 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [ESR1 protein binds to KDM4B intron]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [ESR1 protein binds to RELA promoter]; ESR1 protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KDM4B mRNA]; fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ESR1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of ESR1 mRNA
CTD
PMID:16489053 PMID:21703328 PMID:26519613 PMID:37080397
NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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Esrra
estrogen related receptor, alpha
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ESRRA mRNA
CTD
PMID:37080397
NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208
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Esrrg
estrogen-related receptor gamma
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ESRRG mRNA
CTD
PMID:23196670
NCBI chr 1:187,340,707...187,947,082
Ensembl chr 1:187,340,988...187,947,082
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Etfbkmt
electron transfer flavoprotein beta subunit lysine methyltransferase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ETFBKMT mRNA
CTD
PMID:23196670
NCBI chr 6:149,042,980...149,052,669
Ensembl chr 6:149,041,347...149,052,669
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Ets1
E26 avian leukemia oncogene 1, 5' domain
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ETS1 mRNA
CTD
PMID:23196670
NCBI chr 9:32,547,501...32,669,116
Ensembl chr 9:32,547,517...32,669,116
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Exoc3
exocyst complex component 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EXOC3 mRNA
CTD
PMID:20959002
NCBI chr13:74,317,921...74,358,151
Ensembl chr13:74,317,607...74,356,851
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Exoc3l4
exocyst complex component 3-like 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EXOC3L4 mRNA
CTD
PMID:32119087
NCBI chr12:111,383,864...111,398,114
Ensembl chr12:111,383,451...111,398,112
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Exph5
exophilin 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of EXPH5 mRNA
CTD
PMID:19692669
NCBI chr 9:53,212,814...53,292,466
Ensembl chr 9:53,212,970...53,288,814
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Extl3
exostosin-like glycosyltransferase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EXTL3 mRNA
CTD
PMID:23196670
NCBI chr14:65,289,508...65,387,322
Ensembl chr14:65,289,509...65,387,304
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F11r
F11 receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of F11R mRNA
CTD
PMID:23196670
NCBI chr 1:171,265,129...171,292,161
Ensembl chr 1:171,265,103...171,292,171
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F2r
coagulation factor II thrombin receptor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of F2R mRNA
CTD
PMID:23196670
NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995
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F2rl1
F2R like trypsin receptor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of F2RL1 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr13:95,648,226...95,661,748
Ensembl chr13:95,648,240...95,661,735
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F3
coagulation factor III
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of F3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of F3 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
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Fabp1
fatty acid binding protein 1, liver
increases expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FABP1 mRNA 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of FABP1 mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FABP1 mRNA]
CTD
PMID:30312631
NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
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Fabp4
fatty acid binding protein 4, adipocyte
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FABP4 mRNA
CTD
PMID:22262711 PMID:25304490
NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
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Fabp5
fatty acid binding protein 5, epidermal
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FABP5 mRNA
CTD
PMID:20959002
NCBI chr 3:10,077,645...10,081,670
Ensembl chr 3:10,077,608...10,081,667
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Fads1
fatty acid desaturase 1
increases expression decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FADS1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FADS1 mRNA
CTD
PMID:23196670 PMID:29216392
NCBI chr19:10,160,245...10,174,238
Ensembl chr19:10,160,252...10,174,241
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Fah
fumarylacetoacetate hydrolase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FAH mRNA
CTD
PMID:23196670
NCBI chr 7:84,234,367...84,255,150
Ensembl chr 7:84,234,367...84,255,930
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Fam110b
family with sequence similarity 110, member B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FAM110B mRNA
CTD
PMID:23196670
NCBI chr 4:5,644,009...5,801,101
Ensembl chr 4:5,644,090...6,108,223
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Fam110c
family with sequence similarity 110, member C
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FAM110C mRNA
CTD
PMID:23196670
NCBI chr12:31,123,967...31,129,939
Ensembl chr12:31,123,860...31,130,250
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Fam131b
family with sequence similarity 131, member B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FAM131B mRNA
CTD
PMID:23146750
NCBI chr 6:42,292,239...42,301,574
Ensembl chr 6:42,292,246...42,301,577
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Fam13a
family with sequence similarity 13, member A
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of FAM13A mRNA
CTD
PMID:30744511
NCBI chr 6:58,910,521...59,001,487
Ensembl chr 6:58,909,075...59,001,534
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Fam151a
family with sequence simliarity 151, member A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FAM151A mRNA
CTD
PMID:23196670
NCBI chr 4:106,591,112...106,605,489
Ensembl chr 4:106,591,086...106,605,489
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Fam220a
family with sequence similarity 220, member A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FAM220A mRNA
CTD
PMID:32119087
NCBI chr 5:143,534,475...143,550,286
Ensembl chr 5:143,534,463...143,550,286 Ensembl chr 5:143,534,463...143,550,286
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Fam83f
family with sequence similarity 83, member F
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FAM83F mRNA
CTD
PMID:32119087
NCBI chr15:80,555,829...80,584,626
Ensembl chr15:80,556,048...80,584,626
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Fancd2
Fanconi anemia, complementation group D2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FANCD2 mRNA
CTD
PMID:23196670
NCBI chr 6:113,508,622...113,573,981
Ensembl chr 6:113,508,643...113,573,978
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Fas
Fas cell surface death receptor
multiple interactions increases expression
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FAS mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FAS mRNA
CTD
PMID:28973532
NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
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Fasn
fatty acid synthase
decreases expression multiple interactions affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FASN mRNA 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in decreased expression of FASN mRNA]; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of FASN mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FASN mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of FASN mRNA
CTD
PMID:19692669 PMID:20959002 PMID:28163111 PMID:30312631 PMID:37080397
NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
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Fbln5
fibulin 5
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FBLN5 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FBLN5 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr12:101,712,820...101,785,541
Ensembl chr12:101,712,824...101,785,314
G
Fbn1
fibrillin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FBN1 mRNA
CTD
PMID:23196670
NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913
G
Fbn2
fibrillin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FBN2 mRNA
CTD
PMID:32119087
NCBI chr18:58,141,689...58,343,200
Ensembl chr18:58,141,695...58,343,559
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Fbp1
fructose bisphosphatase 1
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FBP1 mRNA]
CTD
PMID:34256052
NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096
G
Fbp2
fructose bisphosphatase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FBP2 mRNA
CTD
PMID:23196670
NCBI chr13:62,984,698...63,006,214
Ensembl chr13:62,984,691...63,006,236
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Fbxo21
F-box protein 21
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FBXO21 mRNA
CTD
PMID:23994337
NCBI chr 5:118,114,835...118,148,263
Ensembl chr 5:118,114,795...118,148,266
G
Fbxo24
F-box protein 24
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FBXO24 mRNA
CTD
PMID:23146750
NCBI chr 5:137,610,767...137,623,340
Ensembl chr 5:137,610,765...137,627,264
G
Fbxo32
F-box protein 32
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FBXO32 mRNA
CTD
PMID:23196670
NCBI chr15:58,039,275...58,078,288
Ensembl chr15:58,039,275...58,078,328
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Fbxw9
F-box and WD-40 domain protein 9
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of FBXW9 mRNA
CTD
PMID:20702594
NCBI chr 8:85,786,748...85,793,750
Ensembl chr 8:85,786,684...85,793,753
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Fcgr3
Fc receptor, IgG, low affinity III
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FCGR3 mRNA
CTD
PMID:23196670
NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504
G
Fdx1
ferredoxin 1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of FDX1 mRNA
CTD
PMID:16984957
NCBI chr 9:51,854,323...51,874,902
Ensembl chr 9:51,854,606...51,874,856
G
Fdxr
ferredoxin reductase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FDXR mRNA
CTD
PMID:23196670
NCBI chr11:115,158,850...115,167,925
Ensembl chr11:115,158,850...115,167,876
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Fen1
flap structure specific endonuclease 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FEN1 mRNA
CTD
PMID:23196670
NCBI chr19:10,176,496...10,181,757
Ensembl chr19:10,176,496...10,181,533
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Fga
fibrinogen alpha chain
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGA mRNA
CTD
PMID:19692669
NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
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Fgd5
FYVE, RhoGEF and PH domain containing 5
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FGD5 mRNA
CTD
PMID:23994337
NCBI chr 6:91,955,809...92,052,986
Ensembl chr 6:91,955,859...92,052,985
G
Fgf1
fibroblast growth factor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGF1 mRNA
CTD
PMID:23196670
NCBI chr18:38,971,725...39,062,532
Ensembl chr18:38,971,726...39,062,525
G
Fgf13
fibroblast growth factor 13
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGF13 mRNA
CTD
PMID:23196670
NCBI chr X:58,107,499...58,630,932
Ensembl chr X:58,107,505...58,613,431
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Fgf2
fibroblast growth factor 2
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGF2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FGF2 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
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Fgf21
fibroblast growth factor 21
multiple interactions decreases expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in decreased expression of FGF21 mRNA]; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of FGF21 mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGF21 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FGF21 mRNA
CTD
PMID:28163111 PMID:29474705 PMID:30312631
NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914
G
Fgf9
fibroblast growth factor 9
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FGF9 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGF9 mRNA
CTD
PMID:19358281 PMID:23196670
NCBI chr14:58,308,543...58,350,311
Ensembl chr14:58,308,004...58,350,177
G
Fgfr2
fibroblast growth factor receptor 2
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FGFR2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGFR2 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079
G
Fggy
FGGY carbohydrate kinase domain containing
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FGGY mRNA
CTD
PMID:19692669
NCBI chr 4:95,445,717...95,815,176
Ensembl chr 4:95,445,744...95,815,176
G
Fhl2
four and a half LIM domains 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FHL2 mRNA
CTD
PMID:19692669
NCBI chr 1:43,162,233...43,237,501
Ensembl chr 1:43,162,234...43,236,144
G
Fhod1
formin homology 2 domain containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FHOD1 mRNA
CTD
PMID:32119087
NCBI chr 8:106,055,792...106,074,650
Ensembl chr 8:106,055,795...106,074,585
G
Fignl1
fidgetin-like 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FIGNL1 mRNA
CTD
PMID:23196670
NCBI chr11:11,737,429...11,758,962
Ensembl chr11:11,737,431...11,758,962
G
Filip1
filamin A interacting protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FILIP1 mRNA
CTD
PMID:23196670
NCBI chr 9:79,708,461...79,920,135
Ensembl chr 9:79,712,376...79,920,133
G
Fkbp14
FK506 binding protein 14
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FKBP14 mRNA
CTD
PMID:23196670
NCBI chr 6:54,554,590...54,574,329
Ensembl chr 6:54,554,589...54,574,293
G
Fkbp4
FK506 binding protein 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FKBP4 mRNA
CTD
PMID:20959002
NCBI chr 6:128,407,066...128,415,619
Ensembl chr 6:128,406,698...128,415,640
G
Fkbp9
FK506 binding protein 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FKBP9 mRNA
CTD
PMID:23196670
NCBI chr 6:56,809,044...56,856,345
Ensembl chr 6:56,809,044...56,856,343
G
Flnb
filamin, beta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FLNB mRNA
CTD
PMID:19692669
NCBI chr14:14,518,185...14,651,852
Ensembl chr14:14,518,185...14,651,816
G
Flot1
flotillin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FLOT1 mRNA
CTD
PMID:23196670
NCBI chr17:36,134,243...36,143,674
Ensembl chr17:36,134,122...36,143,683
G
Flt1
FMS-like tyrosine kinase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FLT1 mRNA
CTD
PMID:23196670
NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
G
Flvcr2
feline leukemia virus subgroup C cellular receptor 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FLVCR2 mRNA
CTD
PMID:23196670
NCBI chr12:85,793,313...85,860,359
Ensembl chr12:85,793,313...85,860,359
G
Fmo1
flavin containing monooxygenase 1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of FMO1 mRNA
CTD
PMID:16984957
NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179
G
Fmo3
flavin containing monooxygenase 3
multiple interactions increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FMO3 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of FMO3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FMO3 mRNA
CTD
PMID:28163111 PMID:28973532
NCBI chr 1:162,781,368...162,812,097
Ensembl chr 1:162,781,369...162,812,097
G
Fmod
fibromodulin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FMOD mRNA
CTD
PMID:23196670
NCBI chr 1:133,964,992...133,976,018
Ensembl chr 1:133,964,992...133,976,015
G
Fn1
fibronectin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FN1 mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
G
Fos
FBJ osteosarcoma oncogene
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FOS mRNA
CTD
PMID:35618242
NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
G
Foxa2
forkhead box A2
increases expression affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FOXA2 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of FOXA2 mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr 2:147,884,797...147,888,889
Ensembl chr 2:147,884,797...147,888,889
G
Foxa3
forkhead box A3
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of FOXA3 mRNA
CTD
PMID:21703328
NCBI chr 7:18,747,208...18,757,464
Ensembl chr 7:18,747,209...18,757,463
G
Foxd4
forkhead box D4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FOXD4 mRNA
CTD
PMID:23146750
NCBI chr19:24,876,307...24,878,380
Ensembl chr19:24,876,600...24,878,561
G
Foxn3
forkhead box N3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FOXN3 mRNA
CTD
PMID:32119087
NCBI chr12:99,156,340...99,529,926
Ensembl chr12:99,156,337...99,529,841
G
Foxo1
forkhead box O1
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FOXO1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FOXO1 mRNA
CTD
PMID:27509375 PMID:37080397
NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
G
Foxo3
forkhead box O3
multiple interactions decreases phosphorylation
ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of FOXO3 protein]; MDM2 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased phosphorylation of FOXO3 protein]
CTD
PMID:20840854
NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751
G
Foxq1
forkhead box Q1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FOXQ1 mRNA
CTD
PMID:23196670
NCBI chr13:31,742,153...31,744,959
Ensembl chr13:31,740,117...31,744,959
G
Fscn1
fascin actin-bundling protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FSCN1 mRNA
CTD
PMID:32119087
NCBI chr 5:142,946,110...142,958,944
Ensembl chr 5:142,946,098...142,958,940
G
Fshb
follicle stimulating hormone beta
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FSHB protein
CTD
PMID:34256052
NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001
G
Fsip1
fibrous sheath-interacting protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FSIP1 mRNA
CTD
PMID:23196670
NCBI chr 2:117,960,742...118,087,468
Ensembl chr 2:117,960,905...118,087,447
G
Fst
follistatin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FST mRNA
CTD
PMID:23196670
NCBI chr13:114,588,798...114,595,522
Ensembl chr13:114,588,826...114,595,487
G
Ftl1
ferritin light polypeptide 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FTL protein
CTD
PMID:25686467
NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308
G
Fuca1
fucosidase, alpha-L- 1, tissue
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FUCA1 mRNA
CTD
PMID:23146750
NCBI chr 4:135,648,037...135,667,611
Ensembl chr 4:135,648,046...135,667,622
G
Fut7
fucosyltransferase 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FUT7 mRNA
CTD
PMID:23196670
NCBI chr 2:25,312,363...25,316,386
Ensembl chr 2:25,313,279...25,316,386
G
Fxyd1
FXYD domain-containing ion transport regulator 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FXYD1 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 7:30,751,103...30,758,332
Ensembl chr 7:30,751,103...30,756,624
G
Fyn
Fyn proto-oncogene
multiple interactions decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased expression of FYN protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FYN protein
CTD
PMID:24709675
NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377
G
Fzd4
frizzled class receptor 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FZD4 mRNA
CTD
PMID:23196670
NCBI chr 7:89,053,574...89,062,341
Ensembl chr 7:89,053,563...89,062,342
G
Fzd9
frizzled class receptor 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FZD9 mRNA
CTD
PMID:23146750
NCBI chr 5:135,277,792...135,279,901
Ensembl chr 5:135,277,792...135,280,084
G
G0s2
G0/G1 switch gene 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G0S2 mRNA
CTD
PMID:20959002
NCBI chr 1:192,954,468...192,955,496
Ensembl chr 1:192,954,469...192,955,525
G
G6pc1
glucose-6-phosphatase catalytic subunit 1
decreases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G6PC1 mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G6PC1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in decreased expression of G6PC1 mRNA]; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of G6PC1 mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of G6PC1 mRNA]
CTD
PMID:27509375 PMID:28163111 PMID:29474705 PMID:30312631 PMID:34848246
NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
G
G6pdx
glucose-6-phosphate dehydrogenase X-linked
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of G6PDX mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr X:73,453,089...73,472,486
Ensembl chr X:73,453,089...73,472,800
G
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GADD45A mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GADD45A mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
G
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GADD45G mRNA
CTD
PMID:23196670
NCBI chr13:52,000,711...52,002,511
Ensembl chr13:52,000,714...52,002,504
G
Gale
galactose-4-epimerase, UDP
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GALE mRNA
CTD
PMID:23196670
NCBI chr 4:135,690,550...135,695,489
Ensembl chr 4:135,691,038...135,695,489
G
Galnt10
polypeptide N-acetylgalactosaminyltransferase 10
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GALNT10 mRNA
CTD
PMID:23196670
NCBI chr11:57,536,268...57,678,327
Ensembl chr11:57,536,268...57,678,340
G
Galnt14
polypeptide N-acetylgalactosaminyltransferase 14
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GALNT14 mRNA
CTD
PMID:23196670
NCBI chr17:73,800,202...74,019,138
Ensembl chr17:73,800,223...74,017,448
G
Gamt
guanidinoacetate methyltransferase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GAMT mRNA
CTD
PMID:23196670
NCBI chr10:80,093,985...80,096,846
Ensembl chr10:80,093,985...80,096,846
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of GAPDH mRNA
CTD
PMID:37080397
NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430
G
Gar1
GAR1 ribonucleoprotein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GAR1 mRNA
CTD
PMID:23196670
NCBI chr 3:129,618,561...129,625,045
Ensembl chr 3:129,618,561...129,625,045
G
Gas1
growth arrest specific 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GAS1 mRNA
CTD
PMID:23994337
NCBI chr13:60,322,219...60,325,179
Ensembl chr13:60,322,219...60,325,179
G
Gask1b
golgi associated kinase 1B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GASK1B mRNA
CTD
PMID:23196670
NCBI chr 3:79,791,795...79,853,585
Ensembl chr 3:79,791,840...79,853,587
G
Gata4
GATA binding protein 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GATA4 mRNA
CTD
PMID:20959002
NCBI chr14:63,436,363...63,509,161
Ensembl chr14:63,436,371...63,509,141
G
Gata6
GATA binding protein 6
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GATA6 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GATA6 mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr18:11,052,510...11,085,636
Ensembl chr18:11,052,064...11,085,635
G
Gatd3a
glutamine amidotransferase like class 1 domain containing 3A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GATD3 mRNA
CTD
PMID:19692669
NCBI chr10:77,997,900...78,005,589
Ensembl chr10:77,997,900...78,005,616
G
Gcgr
glucagon receptor
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GCGR mRNA
CTD
PMID:23994337
NCBI chr11:120,420,011...120,429,815
Ensembl chr11:120,421,525...120,429,812
G
Gck
glucokinase
decreases expression affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GCK mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of GCK mRNA
CTD
PMID:20959002 PMID:37080397
NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081
G
Gckr
glucokinase regulatory protein
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GCKR mRNA]
CTD
PMID:34256052
NCBI chr 5:31,454,594...31,484,646
Ensembl chr 5:31,454,787...31,484,658
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GCLC mRNA
CTD
PMID:23196670 PMID:23994337
NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
G
Gcnt1
glucosaminyl (N-acetyl) transferase 1, core 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GCNT1 mRNA
CTD
PMID:23196670
NCBI chr19:17,303,505...17,350,208
Ensembl chr19:17,303,505...17,350,208
G
Gcnt2
glucosaminyl (N-acetyl) transferase 2 (I blood group)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GCNT2 mRNA
CTD
PMID:23196670
NCBI chr13:41,013,417...41,114,368
Ensembl chr13:41,013,230...41,114,368
G
Gda
guanine deaminase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GDA mRNA
CTD
PMID:23196670
NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809
G
Gdf15
growth differentiation factor 15
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GDF15 mRNA
CTD
PMID:19692669 PMID:32119087
NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106
G
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GFRA1 mRNA
CTD
PMID:23196670
NCBI chr19:58,224,013...58,444,387
Ensembl chr19:58,224,036...58,444,341
G
Gfra2
glial cell line derived neurotrophic factor family receptor alpha 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GFRA2 mRNA
CTD
PMID:32119087
NCBI chr14:71,127,547...71,217,280
Ensembl chr14:71,127,560...71,217,278
G
Ggt1
gamma-glutamyltransferase 1
multiple interactions decreases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GGT1 mRNA]
CTD
PMID:34256052
NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034
G
Ggta1
glycoprotein galactosyltransferase alpha 1, 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GGTA1 mRNA
CTD
PMID:23146750
NCBI chr 2:35,290,191...35,354,393
Ensembl chr 2:35,290,191...35,353,243
G
Gh
growth hormone
multiple interactions
ISO
[2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of GH1 mRNA
CTD
PMID:19327374
NCBI chr11:106,191,087...106,194,529
Ensembl chr11:106,191,097...106,192,691
G
Ghr
growth hormone receptor
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GHR mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GHR mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974
G
Gk
glycerol kinase
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GK mRNA
CTD
PMID:29216392
NCBI chr X:84,745,543...84,820,425
Ensembl chr X:84,745,543...84,820,425
G
Glb1l3
galactosidase, beta 1 like 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GLB1L3 mRNA
CTD
PMID:23196670
NCBI chr 9:26,729,249...26,773,394
Ensembl chr 9:26,729,249...26,772,186
G
Glipr1
GLI pathogenesis related 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GLIPR1 mRNA
CTD
PMID:23196670
NCBI chr10:111,821,353...111,838,539
Ensembl chr10:111,821,353...111,838,536
G
Glrx2
glutaredoxin 2
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GLRX2 mRNA
CTD
PMID:24378064
NCBI chr 1:143,614,787...143,625,416
Ensembl chr 1:143,592,076...143,625,414
G
Gls2
glutaminase 2 (liver, mitochondrial)
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of GLS2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GLS2 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr10:128,030,504...128,045,873
Ensembl chr10:128,030,326...128,045,873
G
Glud1
glutamate dehydrogenase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GLUD1 mRNA
CTD
PMID:19692669
NCBI chr14:34,032,684...34,066,990
Ensembl chr14:34,032,684...34,067,222
G
Gm18857
predicted gene, 18857
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of AKR1C15 mRNA
CTD
PMID:32119087
NCBI chr13:4,087,952...4,091,308
Ensembl chr13:4,085,245...4,104,757
G
Gmpr
guanosine monophosphate reductase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GMPR mRNA
CTD
PMID:23196670
NCBI chr13:45,660,905...45,699,862
Ensembl chr13:45,660,920...45,707,276
G
Gna14
guanine nucleotide binding protein, alpha 14
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GNA14 mRNA
CTD
PMID:32119087
NCBI chr19:16,413,031...16,590,706
Ensembl chr19:16,413,126...16,588,184
G
Gnb1
guanine nucleotide binding protein (G protein), beta 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GNB1 mRNA
CTD
PMID:20959002
NCBI chr 4:155,575,514...155,643,726
Ensembl chr 4:155,575,818...155,643,726
G
Gng13
guanine nucleotide binding protein (G protein), gamma 13
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of GNG13 mRNA
CTD
PMID:30744511
NCBI chr17:25,936,146...25,938,076
Ensembl chr17:25,936,145...25,938,380
G
Gng8
guanine nucleotide binding protein (G protein), gamma 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GNG8 mRNA
CTD
PMID:23196670
NCBI chr 7:16,625,687...16,629,361
Ensembl chr 7:16,625,711...16,629,361
G
Gnpda1
glucosamine-6-phosphate deaminase 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GNPDA1 mRNA
CTD
PMID:23994337
NCBI chr18:38,460,588...38,472,052
Ensembl chr18:38,460,588...38,472,056
G
Golga3
golgin A3
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GOLGA3 mRNA
CTD
PMID:23994337
NCBI chr 5:110,324,723...110,374,336
Ensembl chr 5:110,324,567...110,374,336
G
Got2
glutamatic-oxaloacetic transaminase 2, mitochondrial
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of GOT2 mRNA
CTD
PMID:21703328
NCBI chr 8:96,590,761...96,615,029
Ensembl chr 8:96,590,762...96,615,175
G
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPAM mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr19:55,056,067...55,115,666
Ensembl chr19:55,055,700...55,115,670
G
Gpc3
glypican 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPC3 mRNA
CTD
PMID:23196670
NCBI chr X:51,361,303...51,702,851
Ensembl chr X:51,361,303...51,702,827
G
Gpc6
glypican 6
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPC6 mRNA
CTD
PMID:29947894
NCBI chr14:117,162,332...118,216,941
Ensembl chr14:117,162,727...118,213,956
G
Gpd2
glycerol phosphate dehydrogenase 2, mitochondrial
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPD2 mRNA
CTD
PMID:23994337
NCBI chr 2:57,127,690...57,260,731
Ensembl chr 2:57,127,647...57,260,731
G
Gpm6b
glycoprotein m6b
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPM6B mRNA
CTD
PMID:23196670
NCBI chr X:165,021,911...165,172,028
Ensembl chr X:165,021,907...165,171,984
G
Gpnmb
glycoprotein (transmembrane) nmb
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPNMB mRNA
CTD
PMID:23196670
NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863
G
Gpr149
G protein-coupled receptor 149
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPR149 mRNA
CTD
PMID:23196670
NCBI chr 3:62,436,851...62,512,861
Ensembl chr 3:62,436,498...62,512,561
G
Gpr15
G protein-coupled receptor 15
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPR15 mRNA
CTD
PMID:32119087
NCBI chr16:58,537,006...58,539,235
Ensembl chr16:58,537,796...58,539,433
G
Gpr35
G protein-coupled receptor 35
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPR35 mRNA
CTD
PMID:23994337
NCBI chr 1:92,875,774...92,913,984
Ensembl chr 1:92,878,587...92,914,113
G
Gpr68
G protein-coupled receptor 68
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPR68 mRNA
CTD
PMID:23146750
NCBI chr12:100,842,941...100,874,457
Ensembl chr12:100,842,941...100,874,457
G
Gpr88
G-protein coupled receptor 88
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPR88 mRNA
CTD
PMID:23196670
NCBI chr 3:116,043,304...116,047,123
Ensembl chr 3:116,043,303...116,047,152
G
Gpt
glutamic pyruvic transaminase, soluble
decreases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPT mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased activity of GPT protein
CTD
PMID:20959002 PMID:33096110
NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
G
Gpx1
glutathione peroxidase 1
multiple interactions decreases expression affects expression
ISO EXP
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPX1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of GPX1 mRNA
CTD
PMID:34256052 PMID:37080397
NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
G
Gpx2
glutathione peroxidase 2
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPX2 mRNA]
CTD
PMID:34256052
NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
G
Gpx3
glutathione peroxidase 3
increases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPX3 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GPX3 mRNA
CTD
PMID:19692669 PMID:20959002 PMID:24378064
NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203
G
Gpx5
glutathione peroxidase 5
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GPX5 mRNA]
CTD
PMID:34256052
NCBI chr13:21,470,599...21,476,897
Ensembl chr13:21,470,599...21,476,901
G
Grb14
growth factor receptor bound protein 14
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GRB14 mRNA
CTD
PMID:23196670
NCBI chr 2:64,742,820...64,853,143
Ensembl chr 2:64,742,820...64,855,331
G
Greb1
gene regulated by estrogen in breast cancer protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GREB1 mRNA
CTD
PMID:32119087
NCBI chr12:16,720,616...16,851,395
Ensembl chr12:16,720,616...16,850,887
G
Grhpr
glyoxylate reductase/hydroxypyruvate reductase
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of GRHPR protein
CTD
PMID:23457121
NCBI chr 4:44,981,394...44,990,734
Ensembl chr 4:44,981,395...44,990,734
G
Grik4
glutamate receptor, ionotropic, kainate 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GRIK4 mRNA
CTD
PMID:32119087
NCBI chr 9:42,431,708...42,856,296
Ensembl chr 9:42,429,431...42,855,789
G
Grina
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GRINA mRNA
CTD
PMID:23196670
NCBI chr15:76,130,917...76,134,109
Ensembl chr15:76,130,964...76,134,104
G
Grip1
glutamate receptor interacting protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GRIP1 mRNA
CTD
PMID:23196670
NCBI chr10:119,289,810...119,923,172
Ensembl chr10:119,289,735...119,923,166
G
Grk5
G protein-coupled receptor kinase 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GRK5 mRNA
CTD
PMID:23196670
NCBI chr19:60,877,995...61,084,406
Ensembl chr19:60,878,187...61,084,406
G
Gsdmd
gasdermin D
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSDMD mRNA
CTD
PMID:23994337
NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257
G
Gsk3b
glycogen synthase kinase 3 beta
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of GSK3B mRNA
CTD
PMID:37080397
NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
G
Gsr
glutathione reductase
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GSR mRNA; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] results in increased expression of GSR protein
CTD
PMID:24378064
NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
G
Gss
glutathione synthetase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSS mRNA
CTD
PMID:23196670
NCBI chr 2:155,405,101...155,434,730
Ensembl chr 2:155,405,101...155,434,730
G
Gsta2
glutathione S-transferase, alpha 2 (Yc2)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTA2 mRNA
CTD
PMID:20959002
NCBI chr 9:78,238,300...78,254,474
Ensembl chr 9:78,238,300...78,263,070
G
Gsta3
glutathione S-transferase, alpha 3
multiple interactions increases expression
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GSTA1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTA1 mRNA
CTD
PMID:24378064 PMID:37080397
NCBI chr 1:21,310,837...21,335,885
Ensembl chr 1:21,310,813...21,335,885
G
Gsta5
glutathione S-transferase alpha 5
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of GSTA2 mRNA
CTD
PMID:20702594
NCBI chr 9:78,197,210...78,212,807
Ensembl chr 9:78,197,205...78,212,807
G
Gstm1
glutathione S-transferase, mu 1
decreases expression increases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSTM1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM1 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GSTM1 mRNA
CTD
PMID:18723825 PMID:20959002 PMID:23196670 PMID:24378064
NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
G
Gstm2
glutathione S-transferase, mu 2
increases expression affects expression multiple interactions decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM2 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of GSTM2 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GSTM2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSTM2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSTM5 mRNA
CTD
PMID:18042819 PMID:18723825 PMID:20702594 PMID:23196670 PMID:24378064
NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
G
Gstm4
glutathione S-transferase, mu 4
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM4 mRNA
CTD
PMID:37080397
NCBI chr 3:107,937,887...107,952,495
Ensembl chr 3:107,947,724...107,952,210
G
Gstm5
glutathione S-transferase, mu 5
decreases expression increases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSTM3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM3 mRNA Sunphenon promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM3 mRNA] AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM3 mRNA]
CTD
PMID:23196670 PMID:24378064 PMID:34256052
NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002
G
Gstp1
glutathione S-transferase, pi 1
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTP1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTP1 mRNA]
CTD
PMID:34256052
NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
G
Gstp2
glutathione S-transferase, pi 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTP2 mRNA
CTD
PMID:23994337
NCBI chr19:4,090,288...4,092,221
Ensembl chr19:4,090,285...4,096,023
G
Gucy1a1
guanylate cyclase 1, soluble, alpha 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GUCY1A1 mRNA
CTD
PMID:23196670
NCBI chr 3:81,999,734...82,053,253
Ensembl chr 3:81,999,734...82,053,096
G
Gusb
glucuronidase, beta
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of GUSB mRNA
CTD
PMID:37080397
NCBI chr 5:130,011,278...130,031,890
Ensembl chr 5:130,017,852...130,031,890
G
Gypc
glycophorin C
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GYPC mRNA
CTD
PMID:23196670
NCBI chr18:32,661,373...32,693,087
Ensembl chr18:32,661,375...32,693,087
G
Gys2
glycogen synthase 2
increases expression decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GYS2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GYS2 mRNA
CTD
PMID:20959002 PMID:37080397
NCBI chr 6:142,368,339...142,418,856
Ensembl chr 6:142,368,339...142,418,835
G
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RT1-BB mRNA
CTD
PMID:20959002
NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
G
H2-Ea
histocompatibility 2, class II antigen E alpha
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RT1-DA mRNA
CTD
PMID:20959002
NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,560,926...34,563,618
G
H2ax
H2A.X variant histone
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of H2AX protein 2,4,3',5'-tetramethoxystilbene inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of H2AX protein]
CTD
PMID:31733235
NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
G
H2bc1
H2B clustered histone 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of H2BC1 mRNA
CTD
PMID:23196670
NCBI chr13:24,117,708...24,118,139
Ensembl chr13:24,117,756...24,118,139
G
H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of H6PD mRNA
CTD
PMID:23994337
NCBI chr 4:150,063,931...150,093,480
Ensembl chr 4:150,063,932...150,093,480
G
Hacl1
2-hydroxyacyl-CoA lyase 1
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of HACL1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HACL1 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr14:31,329,183...31,364,201
Ensembl chr14:31,320,687...31,363,243
G
Hal
histidine ammonia lyase
multiple interactions decreases expression increases expression
ISO EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of HAL mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HAL mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HAL mRNA
CTD
PMID:16984957 PMID:19692669 PMID:20959002 PMID:23994337
NCBI chr10:93,324,630...93,352,623
Ensembl chr10:93,324,630...93,355,166
G
Hamp
hepcidin antimicrobial peptide
decreases expression decreases response to substance multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HAMP mRNA HAMP protein results in decreased susceptibility to 3,4,5,3',4'-pentachlorobiphenyl [3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of HAMP mRNA
CTD
PMID:25686467 PMID:30744511
NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
G
Hamp2
hepcidin antimicrobial peptide 2
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HAMP2 mRNA
CTD
PMID:28213091
NCBI chr 7:30,621,797...30,623,606
Ensembl chr 7:30,621,797...30,624,106
G
Hap1
huntingtin-associated protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HAP1 mRNA
CTD
PMID:32119087
NCBI chr11:100,238,153...100,247,808
Ensembl chr11:100,238,153...100,246,954
G
Has2
hyaluronan synthase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HAS2 mRNA
CTD
PMID:32119087
NCBI chr15:56,529,023...56,557,942
Ensembl chr15:56,529,023...56,557,935
G
Hat1
histone aminotransferase 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HAT1 mRNA
CTD
PMID:37080397
NCBI chr 2:71,219,604...71,271,966
Ensembl chr 2:71,219,302...71,271,966
G
Haus4
HAUS augmin-like complex, subunit 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HAUS4 mRNA
CTD
PMID:23196670
NCBI chr14:54,779,242...54,792,446
Ensembl chr14:54,779,242...54,792,073
G
Havcr2
hepatitis A virus cellular receptor 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HAVCR2 mRNA
CTD
PMID:32119087
NCBI chr11:46,345,758...46,372,082
Ensembl chr11:46,345,762...46,372,082
G
Hbegf
heparin-binding EGF-like growth factor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HBEGF mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
G
Hdac1
histone deacetylase 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HDAC1 mRNA
CTD
PMID:37080397
NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506
G
Hdac3
histone deacetylase 3
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HDAC3 mRNA
CTD
PMID:37080397
NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069
G
Hdac4
histone deacetylase 4
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HDAC4 mRNA
CTD
PMID:37080397
NCBI chr 1:91,856,501...92,123,424
Ensembl chr 1:91,856,501...92,123,421
G
Hdac9
histone deacetylase 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HDAC9 mRNA
CTD
PMID:32119087
NCBI chr12:34,097,579...34,967,094
Ensembl chr12:34,097,579...34,967,094
G
Hdc
histidine decarboxylase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HDC mRNA
CTD
PMID:20959002
NCBI chr 2:126,435,579...126,465,942
Ensembl chr 2:126,435,587...126,461,219
G
Helz2
helicase with zinc finger 2, transcriptional coactivator
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HELZ2 mRNA
CTD
PMID:32119087
NCBI chr 2:180,869,408...180,883,851
Ensembl chr 2:180,869,408...180,883,820
G
Herc6
hect domain and RLD 6
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HERC6 mRNA
CTD
PMID:32119087
NCBI chr 6:57,557,977...57,642,121
Ensembl chr 6:57,557,985...57,641,617
G
Hes1
hes family bHLH transcription factor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HES1 mRNA
CTD
PMID:23196670
NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614
G
Hexim2
hexamethylene bis-acetamide inducible 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HEXIM2 mRNA
CTD
PMID:32119087
NCBI chr11:103,014,086...103,030,734
Ensembl chr11:103,023,255...103,030,702
G
Hgf
hepatocyte growth factor
affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HGF mRNA
CTD
PMID:21703328 PMID:37080397
NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
G
Hic1
hypermethylated in cancer 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HIC1 mRNA
CTD
PMID:32119087
NCBI chr11:75,052,203...75,059,970
Ensembl chr11:75,055,391...75,060,345
G
Hif1a
hypoxia inducible factor 1, alpha subunit
affects localization affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl affects the localization of HIF1A protein 3,4,5,3',4'-pentachlorobiphenyl affects the expression of HIF1A mRNA
CTD
PMID:24916446 PMID:37080397
NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
G
Higd1a
HIG1 domain family, member 1A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HIGD1A mRNA
CTD
PMID:23196670
NCBI chr 9:121,677,623...121,686,862
Ensembl chr 9:121,677,629...121,687,428
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Hipk2
homeodomain interacting protein kinase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HIPK2 mRNA
CTD
PMID:23146750
NCBI chr 6:38,664,447...38,853,236
Ensembl chr 6:38,671,325...38,853,099
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Hivep2
human immunodeficiency virus type I enhancer binding protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HIVEP2 mRNA
CTD
PMID:23196670
NCBI chr10:13,841,819...14,027,122
Ensembl chr10:13,841,819...14,027,118
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Hk2
hexokinase 2
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HK2 mRNA]
CTD
PMID:34256052 PMID:35618242
NCBI chr 6:82,702,004...82,751,437
Ensembl chr 6:82,702,006...82,751,435
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Hkdc1
hexokinase domain containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HKDC1 mRNA
CTD
PMID:23146750
NCBI chr10:62,218,916...62,259,490
Ensembl chr10:62,218,916...62,258,270
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Hmgb2
high mobility group box 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMGB2 mRNA
CTD
PMID:23196670
NCBI chr 8:57,964,877...57,969,033
Ensembl chr 8:57,964,941...57,969,033
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Hmgcr
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMGCR mRNA
CTD
PMID:20574914 PMID:23196670
NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
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Hmgcs1
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMGCS1 mRNA
CTD
PMID:23196670
NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796
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Hmgcs2
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
decreases expression increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMGCS2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMGCS2 mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMGCS2 mRNA]
CTD
PMID:23196670 PMID:26396156 PMID:32119087 PMID:34848246
NCBI chr 3:98,187,747...98,218,054
Ensembl chr 3:98,187,751...98,218,054
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Hmgn3
high mobility group nucleosomal binding domain 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMGN3 mRNA
CTD
PMID:32119087
NCBI chr 9:82,991,995...83,029,411
Ensembl chr 9:82,992,001...83,028,738
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Hmox1
heme oxygenase 1
affects expression multiple interactions increases expression decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HMOX1 mRNA [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of HMOX1 mRNA; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 protein]]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMOX1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMOX1 mRNA [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMOX1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 protein
CTD
PMID:21703328 PMID:28163111 PMID:30768972 PMID:35618242 PMID:37598416
NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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Hnf4a
hepatic nuclear factor 4, alpha
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HNF4A mRNA
CTD
PMID:20959002
NCBI chr 2:163,348,731...163,414,827
Ensembl chr 2:163,348,728...163,414,830
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Hoxb2
homeobox B2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HOXB2 mRNA
CTD
PMID:20959002
NCBI chr11:96,242,458...96,244,846
Ensembl chr11:96,241,351...96,244,838
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Hoxb9
homeobox B9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HOXB9 mRNA
CTD
PMID:23146750
NCBI chr11:96,162,156...96,167,421
Ensembl chr11:96,162,283...96,167,421
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Hpd
4-hydroxyphenylpyruvic acid dioxygenase
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of HPD mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HPD mRNA
CTD
PMID:16984957 PMID:23196670
NCBI chr 5:123,309,870...123,320,786
Ensembl chr 5:123,309,870...123,320,790
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Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HS3ST1 mRNA
CTD
PMID:23196670
NCBI chr 5:39,771,278...39,802,791
Ensembl chr 5:39,771,278...39,912,818
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Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD11B1 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr 1:192,903,917...192,946,345
Ensembl chr 1:192,903,942...192,946,383
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Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HSD11B2 mRNA
CTD
PMID:23146750
NCBI chr 8:106,245,378...106,250,620
Ensembl chr 8:106,245,387...106,250,620
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Hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
decreases expression increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HSD17B1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B1 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B1 mRNA]
CTD
PMID:25433332 PMID:34256052
NCBI chr11:100,968,792...100,972,014
Ensembl chr11:100,969,237...100,971,353
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Hsd17b2
hydroxysteroid (17-beta) dehydrogenase 2
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B2 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B2 mRNA]
CTD
PMID:19692669 PMID:34256052
NCBI chr 8:118,427,752...118,485,767
Ensembl chr 8:118,428,643...118,485,766
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Hsd17b3
hydroxysteroid (17-beta) dehydrogenase 3
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B3 mRNA]
CTD
PMID:34256052
NCBI chr13:64,206,088...64,237,076
Ensembl chr13:64,206,080...64,237,044
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Hsd17b7
hydroxysteroid (17-beta) dehydrogenase 7
decreases expression increases expression decreases methylation multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HSD17B7 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B7 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased methylation of HSD17B7 promoter 3',4'-dimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B7 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B7 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B7 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSD17B7 protein
CTD
PMID:20959002 PMID:23196670 PMID:27663891
NCBI chr 1:169,777,109...169,796,757
Ensembl chr 1:169,777,104...169,796,810
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Hsdl2
hydroxysteroid dehydrogenase like 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSDL2 mRNA
CTD
PMID:19692669
NCBI chr 4:59,581,515...59,618,694
Ensembl chr 4:59,581,563...59,618,689
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Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of HSP90AB1 mRNA
CTD
PMID:21703328
NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197
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Hspa4l
heat shock protein 4 like
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSPA4L mRNA
CTD
PMID:23994337
NCBI chr 3:40,698,664...40,750,538
Ensembl chr 3:40,699,814...40,750,538
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Hspa5
heat shock protein 5
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HSPA5 mRNA
CTD
PMID:37080397
NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
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Hspa8
heat shock protein 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSPA8 mRNA
CTD
PMID:32119087
NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
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Hspb1
heat shock protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HSPB1 mRNA
CTD
PMID:23196670
NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
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Hspb2
heat shock protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HSPB2 mRNA
CTD
PMID:23196670
NCBI chr 9:50,662,372...50,663,654
Ensembl chr 9:50,662,378...50,663,654
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Htr2b
5-hydroxytryptamine (serotonin) receptor 2B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HTR2B mRNA
CTD
PMID:23196670
NCBI chr 1:86,025,268...86,043,960
Ensembl chr 1:86,026,748...86,039,692
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Hyal1
hyaluronoglucosaminidase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HYAL1 mRNA
CTD
PMID:23196670
NCBI chr 9:107,454,149...107,458,898
Ensembl chr 9:107,454,126...107,458,909
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Icam1
intercellular adhesion molecule 1
increases expression multiple interactions increases secretion affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ICAM1 mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ICAM1 protein]; [perfluorooctane sulfonic acid co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of ICAM1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ICAM1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of ICAM1 protein alternative form 3,4,5,3',4'-pentachlorobiphenyl affects the expression of ICAM1 mRNA
CTD
PMID:20959002 PMID:22262711 PMID:26519613 PMID:28973532 PMID:29216392 PMID:33096110 PMID:35618242 PMID:37080397 More...
NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
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Icam5
intercellular adhesion molecule 5, telencephalin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ICAM5 mRNA
CTD
PMID:23146750
NCBI chr 9:20,943,372...20,950,331
Ensembl chr 9:20,943,369...20,950,332
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Icosl
icos ligand
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ICOSLG mRNA
CTD
PMID:32119087
NCBI chr10:77,904,921...77,915,359
Ensembl chr10:77,905,136...77,919,747
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Id1
inhibitor of DNA binding 1, HLH protein
decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ID1 mRNA
CTD
PMID:23196670 PMID:23994337
NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330
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Id2
inhibitor of DNA binding 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ID2 mRNA
CTD
PMID:23196670
NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
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Id4
inhibitor of DNA binding 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ID4 mRNA
CTD
PMID:23196670
NCBI chr13:48,414,592...48,419,504
Ensembl chr13:48,414,704...48,419,502
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Ide
insulin degrading enzyme
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of IDE mRNA
CTD
PMID:37080397
NCBI chr19:37,246,140...37,341,664
Ensembl chr19:37,246,142...37,340,010
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Idh2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of IDH2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IDH2 mRNA
CTD
PMID:16984957
NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140
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Idi1
isopentenyl-diphosphate delta isomerase
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IDI1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IDI1 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr13:8,935,642...8,942,432
Ensembl chr13:8,935,537...8,942,487
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Ier3
immediate early response 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IER3 mRNA
CTD
PMID:19692669 PMID:20959002 PMID:32119087
NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815
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Ifi44
interferon-induced protein 44
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IFI44 mRNA
CTD
PMID:32119087
NCBI chr 3:151,436,559...151,455,580
Ensembl chr 3:151,436,559...151,455,597
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Ifi44l
interferon-induced protein 44 like
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IFI44L mRNA
CTD
PMID:23146750 PMID:32119087
NCBI chr 3:151,464,374...151,468,528
Ensembl chr 3:151,464,374...151,468,529
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Ifng
interferon gamma
increases secretion multiple interactions decreases secretion decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IFNG protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL2 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL3 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL4 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL6 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA]; [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 mRNA]; [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of HMOX1 mRNA]; [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NFE2L2 mRNA]; [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of IFNG protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IFNG mRNA
CTD
PMID:29216392 PMID:30768972 PMID:31563530
NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
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Igf1
insulin-like growth factor 1
multiple interactions decreases expression increases expression affects expression
ISO EXP
[2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of IGF1 protein; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGF1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGF1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGF1 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of IGF1 mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IGF1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of IGF1 mRNA
CTD
PMID:19327374 PMID:19692669 PMID:23196670 PMID:30312631 PMID:31820026 PMID:34848246 PMID:37080397 More...
NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
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Igf1r
insulin-like growth factor I receptor
decreases expression affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGF1R mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of IGF1R mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416
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Igf2r
insulin-like growth factor 2 receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGF2R mRNA
CTD
PMID:23196670
NCBI chr17:12,901,293...12,988,593
Ensembl chr17:12,901,293...12,988,551
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Igfbp1
insulin-like growth factor binding protein 1
increases expression affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IGFBP1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of IGFBP1 mRNA
CTD
PMID:19692669 PMID:20959002 PMID:37080397
NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
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Igfbp2
insulin-like growth factor binding protein 2
decreases expression affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGFBP2 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of IGFBP2 mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr 1:72,863,650...72,891,633
Ensembl chr 1:72,863,662...72,891,633
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Igfbp3
insulin-like growth factor binding protein 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IGFBP3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IGFBP3 protein
CTD
PMID:10919282 PMID:22262711
NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923
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Igfbp4
insulin-like growth factor binding protein 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGFBP4 mRNA
CTD
PMID:23196670
NCBI chr11:98,930,820...98,943,481
Ensembl chr11:98,932,070...98,945,218
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Igfbp5
insulin-like growth factor binding protein 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGFBP5 mRNA
CTD
PMID:23196670
NCBI chr 1:72,897,224...72,914,024
Ensembl chr 1:72,897,091...72,914,043
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Igfbp6
insulin-like growth factor binding protein 6
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGFBP6 mRNA
CTD
PMID:23196670
NCBI chr15:102,052,621...102,057,947
Ensembl chr15:102,052,797...102,057,946
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Igfbp7
insulin-like growth factor binding protein 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGFBP7 mRNA
CTD
PMID:23196670
NCBI chr 5:77,497,092...77,555,892
Ensembl chr 5:77,497,087...77,555,888
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Iglon5
IgLON family member 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGLON5 mRNA
CTD
PMID:32119087
NCBI chr 7:43,122,325...43,139,635
Ensembl chr 7:43,122,328...43,139,499
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Igsf8
immunoglobulin superfamily, member 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IGSF8 mRNA
CTD
PMID:23196670
NCBI chr 1:172,139,934...172,147,410
Ensembl chr 1:172,089,208...172,147,408
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Ihh
Indian hedgehog
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IHH mRNA
CTD
PMID:32119087
NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831
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Ikbkb
inhibitor of kappaB kinase beta
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of IKBKB mRNA
CTD
PMID:37080397
NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605
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Il10
interleukin 10
decreases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of IL10 mRNA; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 protein
CTD
PMID:23196670 PMID:28973532 PMID:37598416
NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
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Il11
interleukin 11
multiple interactions
ISO
[AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased expression of IL11 mRNA
CTD
PMID:34256052
NCBI chr 7:4,775,372...4,785,877
Ensembl chr 7:4,775,372...4,785,858
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Il11ra1
interleukin 11 receptor subunit alpha 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL11RA1 mRNA
CTD
PMID:23196670
NCBI chr 4:41,760,443...41,769,473
Ensembl chr 4:41,699,989...41,769,474
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Il12a
interleukin 12a
multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of [IL12A protein binds to IL12B protein]
CTD
PMID:29216392
NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880
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Il12b
interleukin 12b
multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of [IL12A protein binds to IL12B protein]
CTD
PMID:29216392
NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
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Il13
interleukin 13
increases secretion
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IL13 protein
CTD
PMID:29216392
NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
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Il15
interleukin 15
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL15 mRNA
CTD
PMID:28351761
NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851
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Il17rb
interleukin 17 receptor B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL17RB mRNA
CTD
PMID:19692669
NCBI chr14:29,718,125...29,730,853
Ensembl chr14:29,718,092...29,730,853
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Il17re
interleukin 17 receptor E
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL17RE mRNA
CTD
PMID:23196670
NCBI chr 6:113,435,659...113,447,719
Ensembl chr 6:113,435,445...113,447,719
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Il18
interleukin 18
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of IL18 mRNA
CTD
PMID:21703328
NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
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Il1a
interleukin 1 alpha
increases expression affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1A mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of IL1A mRNA
CTD
PMID:26519613 PMID:28351761 PMID:35618242 PMID:37080397
NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
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Il1b
interleukin 1 beta
multiple interactions decreases expression increases expression increases secretion
ISO EXP
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B mRNA]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IL1B protein]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL1B mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B protein Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B protein]
CTD
PMID:22262711 PMID:25433332 PMID:26519613 PMID:28351761 PMID:29216392 PMID:30768972 PMID:35618242 PMID:37080397 PMID:37598416 More...
NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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Il1r1
interleukin 1 receptor, type I
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1R1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL1R1 mRNA
CTD
PMID:20959002 PMID:32119087 PMID:34256052 PMID:35618242
NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
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Il1rap
interleukin 1 receptor accessory protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL1RAP mRNA
CTD
PMID:23196670
NCBI chr16:26,400,259...26,548,878
Ensembl chr16:26,400,454...26,548,867
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Il1rl1
interleukin 1 receptor-like 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1RL1 mRNA
CTD
PMID:23196670
NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575
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Il1rn
interleukin 1 receptor antagonist
increases expression multiple interactions increases secretion
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1RN mRNA 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IL1RN protein]; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1RN mRNA]
CTD
PMID:22262711 PMID:28351761 PMID:30768972
NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
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Il2
interleukin 2
decreases expression decreases secretion
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of IL2 protein
CTD
PMID:31563530
NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
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Il24
interleukin 24
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL24 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL24 protein
CTD
PMID:28351761
NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
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Il33
interleukin 33
multiple interactions decreases expression increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of IL33 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL33 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL33 mRNA
CTD
PMID:16984957 PMID:20959002 PMID:34256052 PMID:35618242
NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118
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Il34
interleukin 34
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL34 mRNA
CTD
PMID:32119087 PMID:35618242
NCBI chr 8:111,467,809...111,532,579
Ensembl chr 8:111,468,461...111,532,556
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Il4ra
interleukin 4 receptor, alpha
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL4RA mRNA
CTD
PMID:23196670
NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
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Il5
interleukin 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL5 mRNA
CTD
PMID:28351761
NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
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Il6
interleukin 6
increases expression multiple interactions increases secretion
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 protein [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA; [aroclor 1260 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of IL6 mRNA; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 protein]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 protein] 3',4'-dimethoxyflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IL6 protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL6 mRNA]; KDM4B protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; lipoxin A4 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IL6 protein]
CTD
PMID:19265715 PMID:26519613 PMID:27663891 PMID:28351761 PMID:28973532 PMID:30312631 PMID:30768972 PMID:33026256 PMID:35618242 PMID:37598416 More...
NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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Il6st
interleukin 6 signal transducer
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6ST mRNA
CTD
PMID:34256052
NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620
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Impa2
inositol monophosphatase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IMPA2 mRNA
CTD
PMID:20959002
NCBI chr18:67,422,246...67,454,375
Ensembl chr18:67,422,256...67,455,542
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Inhbb
inhibin beta-B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of INHBB mRNA
CTD
PMID:32119087
NCBI chr 1:119,343,193...119,349,978
Ensembl chr 1:119,343,195...119,349,978
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Inhbe
inhibin beta-E
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of INHBE mRNA
CTD
PMID:23196670
NCBI chr10:127,185,271...127,187,717
Ensembl chr10:127,184,726...127,190,280
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Inpp5b
inositol polyphosphate-5-phosphatase B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of INPP5B mRNA
CTD
PMID:32119087
NCBI chr 4:124,635,620...124,695,304
Ensembl chr 4:124,635,643...124,695,304
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Ins1
insulin I
increases expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of INS1 mRNA 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of INS1 mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of INS1 mRNA]
CTD
PMID:30312631
NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
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Insig1
insulin induced gene 1
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of INSIG1 mRNA
CTD
PMID:23146750 PMID:23196670 PMID:29216392
NCBI chr 5:28,276,410...28,283,660
Ensembl chr 5:28,276,361...28,283,660
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Insl6
insulin-like 6
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of INSL6 mRNA
CTD
PMID:20702594
NCBI chr19:29,298,754...29,302,718
Ensembl chr19:29,298,744...29,302,756
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Insr
insulin receptor
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of INSR mRNA
CTD
PMID:37080397
NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
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Ints12
integrator complex subunit 12
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of INTS12 mRNA
CTD
PMID:23196670
NCBI chr 3:132,797,616...132,816,749
Ensembl chr 3:132,797,601...132,816,749
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Irak1
interleukin-1 receptor-associated kinase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IRAK1 mRNA
CTD
PMID:35618242
NCBI chr X:73,057,520...73,067,527
Ensembl chr X:73,057,520...73,067,524
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Irf1
interferon regulatory factor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IRF1 mRNA
CTD
PMID:23196670
NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
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Irf7
interferon regulatory factor 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IRF7 mRNA
CTD
PMID:32119087
NCBI chr 7:140,843,096...140,846,412
Ensembl chr 7:140,842,619...140,846,394
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Irf9
interferon regulatory factor 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IRF9 mRNA
CTD
PMID:23196670
NCBI chr14:55,841,442...55,847,487
Ensembl chr14:55,841,028...55,847,487
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Irs1
insulin receptor substrate 1
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IRS1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IRS1 mRNA
CTD
PMID:20959002 PMID:35618242 PMID:37080397
NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137
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Irs2
insulin receptor substrate 2
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of IRS2 mRNA
CTD
PMID:37080397
NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458
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Isg20
interferon-stimulated protein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ISG20 mRNA
CTD
PMID:23196670
NCBI chr 7:78,561,136...78,570,144
Ensembl chr 7:78,563,172...78,570,144
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Isl1
ISL1 transcription factor, LIM/homeodomain
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ISL1 mRNA
CTD
PMID:23196670
NCBI chr13:116,434,806...116,446,224
Ensembl chr13:116,434,817...116,446,225
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Itga1
integrin alpha 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITGA1 mRNA
CTD
PMID:23196670
NCBI chr13:115,094,615...115,238,500
Ensembl chr13:115,089,632...115,238,500
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Itga2b
integrin alpha 2b
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITGA2B mRNA
CTD
PMID:20959002
NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948
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Itga7
integrin alpha 7
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of ITGA7 mRNA
CTD
PMID:16984957
NCBI chr10:128,769,633...128,794,155
Ensembl chr10:128,769,645...128,794,155
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Itga8
integrin alpha 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITGA8 mRNA
CTD
PMID:32119087
NCBI chr 2:12,111,443...12,306,755
Ensembl chr 2:12,111,443...12,306,733
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Itgb5
integrin beta 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ITGB5 mRNA
CTD
PMID:23196670
NCBI chr16:33,650,021...33,769,708
Ensembl chr16:33,650,035...33,769,708
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Itgb8
integrin beta 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ITGB8 mRNA
CTD
PMID:35618242
NCBI chr12:119,121,757...119,202,891
Ensembl chr12:119,121,757...119,202,537
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Itih4
inter alpha-trypsin inhibitor, heavy chain 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITIH4 mRNA
CTD
PMID:23196670
NCBI chr14:30,608,433...30,623,943
Ensembl chr14:30,608,433...30,624,310
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Itpr1
inositol 1,4,5-trisphosphate receptor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITPR1 mRNA
CTD
PMID:20959002
NCBI chr 6:108,190,044...108,528,077
Ensembl chr 6:108,190,057...108,528,070
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Itpr3
inositol 1,4,5-triphosphate receptor 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITPR3 mRNA
CTD
PMID:23196670
NCBI chr17:27,275,976...27,341,197
Ensembl chr17:27,276,278...27,341,197
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Itsn1
intersectin 1 (SH3 domain protein 1A)
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ITSN1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ITSN1 mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr16:91,526,198...91,717,479
Ensembl chr16:91,526,169...91,717,485
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Jam3
junction adhesion molecule 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of JAM3 mRNA
CTD
PMID:23196670
NCBI chr 9:27,008,680...27,066,739
Ensembl chr 9:27,008,680...27,066,717
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Jdp2
Jun dimerization protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JDP2 mRNA
CTD
PMID:23196670
NCBI chr12:85,645,190...85,686,652
Ensembl chr12:85,645,801...85,686,652
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Jmjd6
jumonji domain containing 6
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JMJD6 mRNA
CTD
PMID:23196670
NCBI chr11:116,728,258...116,734,593
Ensembl chr11:116,728,258...116,734,275
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Josd1
Josephin domain containing 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JOSD1 mRNA
CTD
PMID:23994337
NCBI chr15:79,558,451...79,572,073
Ensembl chr15:79,558,452...79,572,120
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Jpt2
Jupiter microtubule associated homolog 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JPT2 mRNA
CTD
PMID:23196670
NCBI chr17:25,161,444...25,179,597
Ensembl chr17:25,156,393...25,179,663
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Jun
jun proto-oncogene
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JUN mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JUN protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of JUN mRNA
CTD
PMID:16081525 PMID:19692669 PMID:20959002
NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
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Jund
jun D proto-oncogene
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of JUND mRNA
CTD
PMID:23196670
NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265
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Jup
junction plakoglobin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of JUP mRNA
CTD
PMID:23196670
NCBI chr11:100,259,682...100,288,639
Ensembl chr11:100,259,784...100,288,589
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Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KCND3 mRNA
CTD
PMID:23196670
NCBI chr 3:105,359,206...105,581,318
Ensembl chr 3:105,359,646...105,581,318
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Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
affects activity
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the activity of KCNH2 protein
CTD
PMID:22676973
NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
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Kcnip1
Kv channel-interacting protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KCNIP1 mRNA
CTD
PMID:32119087
NCBI chr11:33,579,339...33,943,854
Ensembl chr11:33,579,339...33,943,152
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Kcnj12
potassium inwardly-rectifying channel, subfamily J, member 12
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KCNJ12 mRNA
CTD
PMID:23196670
NCBI chr11:60,912,970...60,964,095
Ensembl chr11:60,913,390...60,961,957
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Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KCNJ2 mRNA
CTD
PMID:23196670
NCBI chr11:110,956,990...110,967,651
Ensembl chr11:110,956,990...110,967,647
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Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KCNJ5 mRNA
CTD
PMID:23146750
NCBI chr 9:32,226,002...32,255,640
Ensembl chr 9:32,226,003...32,255,646
G
Kcnk1
potassium channel, subfamily K, member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KCNK1 mRNA
CTD
PMID:23196670
NCBI chr 8:126,718,692...126,757,424
Ensembl chr 8:126,721,909...126,757,424
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Kcnmb1
potassium large conductance calcium-activated channel, subfamily M, beta member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KCNMB1 mRNA
CTD
PMID:32119087
NCBI chr11:33,912,955...33,923,641
Ensembl chr11:33,913,013...33,923,641
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Kcns1
K+ voltage-gated channel, subfamily S, 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KCNS1 mRNA
CTD
PMID:32119087
NCBI chr 2:164,005,539...164,013,865
Ensembl chr 2:164,005,539...164,013,033
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Kcnv1
potassium channel, subfamily V, member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KCNV1 mRNA
CTD
PMID:23196670
NCBI chr15:44,959,482...44,979,375
Ensembl chr15:44,969,680...44,978,316
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Kdm4b
lysine (K)-specific demethylase 4B
multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [ESR1 protein binds to KDM4B intron]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [KDM4B protein binds to RELA promoter]; ESR1 protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KDM4B mRNA]; KDM4B protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; KDM4B protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA mRNA]
CTD
PMID:26519613
NCBI chr17:56,632,975...56,710,774
Ensembl chr17:56,633,062...56,709,870
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Keap1
kelch-like ECH-associated protein 1
decreases expression multiple interactions affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KEAP1 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased expression of KEAP1 protein] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of KEAP1 mRNA
CTD
PMID:24709675 PMID:31563530
NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
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Khk
ketohexokinase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KHK mRNA
CTD
PMID:20959002
NCBI chr 5:31,078,780...31,088,592
Ensembl chr 5:31,078,775...31,088,592
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Kif15
kinesin family member 15
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KIF15 mRNA
CTD
PMID:23196670
NCBI chr 9:122,780,146...122,847,798
Ensembl chr 9:122,780,111...122,847,798
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Kif22
kinesin family member 22
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KIF22 mRNA
CTD
PMID:23196670
NCBI chr 7:126,626,901...126,641,639
Ensembl chr 7:126,626,901...126,641,643
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Kifc1
kinesin family member C1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KIFC1 mRNA
CTD
PMID:23196670
NCBI chr17:34,094,640...34,109,607
Ensembl chr17:34,094,633...34,109,635
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Kifc2
kinesin family member C2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KIFC2 mRNA
CTD
PMID:23196670
NCBI chr15:76,543,984...76,552,396
Ensembl chr15:76,544,058...76,552,396
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Kitl
kit ligand
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KITL mRNA
CTD
PMID:23196670
NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278
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Kl
klotho
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Cholecalciferol] results in increased expression of KL mRNA
CTD
PMID:31820026
NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282
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Klc4
kinesin light chain 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KLC4 mRNA
CTD
PMID:32119087
NCBI chr17:46,941,550...46,957,115
Ensembl chr17:46,941,550...46,956,948
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Klf10
Kruppel-like transcription factor 10
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KLF10 mRNA
CTD
PMID:23196670
NCBI chr15:38,291,702...38,300,950
Ensembl chr15:38,291,707...38,300,950
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Klf6
Kruppel-like transcription factor 6
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KLF6 mRNA
CTD
PMID:23196670
NCBI chr13:5,911,488...5,920,392
Ensembl chr13:5,911,481...5,920,393
G
Klhl3
kelch-like 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KLHL3 mRNA
CTD
PMID:32119087
NCBI chr13:58,148,040...58,271,288
Ensembl chr13:58,148,042...58,261,406
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Klrg1
killer cell lectin-like receptor subfamily G, member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KLRG1 mRNA
CTD
PMID:20959002
NCBI chr 6:122,247,555...122,259,792
Ensembl chr 6:122,247,555...122,259,841
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Kmo
kynurenine 3-monooxygenase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KMO mRNA
CTD
PMID:20959002
NCBI chr 1:175,459,759...175,488,419
Ensembl chr 1:175,447,947...175,489,682
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Knstrn
kinetochore-localized astrin/SPAG5 binding
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KNSTRN mRNA
CTD
PMID:23196670
NCBI chr 2:118,644,470...118,667,691
Ensembl chr 2:118,644,484...118,684,438
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Kpna6
karyopherin subunit alpha 6
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KPNA6 mRNA
CTD
PMID:23994337
NCBI chr 4:129,537,772...129,566,560
Ensembl chr 4:129,537,773...129,566,560
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Krt10
keratin 10
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of KRT10 protein
CTD
PMID:23457121
NCBI chr11:99,276,080...99,288,631
Ensembl chr11:99,276,080...99,280,190
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Krt14
keratin 14
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KRT14 mRNA
CTD
PMID:23196670
NCBI chr11:100,093,988...100,098,336
Ensembl chr11:100,093,988...100,098,374
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Krt15
keratin 15
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KRT15 mRNA
CTD
PMID:23196670
NCBI chr11:100,022,585...100,026,775
Ensembl chr11:100,022,584...100,026,754
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Krt18
keratin 18
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KRT18 mRNA
CTD
PMID:32119087
NCBI chr15:101,936,651...101,940,461
Ensembl chr15:101,936,615...101,940,462
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Krt19
keratin 19
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KRT19 mRNA
CTD
PMID:23196670
NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491
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Krt76
keratin 76
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of KRT76 mRNA
CTD
PMID:32119087
NCBI chr15:101,792,786...101,801,355
Ensembl chr15:101,792,786...101,801,355
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Kynu
kynureninase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of KYNU mRNA
CTD
PMID:19692669
NCBI chr 2:43,445,270...43,572,734
Ensembl chr 2:43,445,341...43,572,734
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L3hypdh
L-3-hydroxyproline dehydratase (trans-)
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of L3HYPDH mRNA
CTD
PMID:16984957
NCBI chr12:72,114,745...72,132,206
Ensembl chr12:72,120,202...72,132,213
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Lama1
laminin, alpha 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LAMA1 mRNA
CTD
PMID:32119087
NCBI chr17:68,004,129...68,129,640
Ensembl chr17:68,004,254...68,129,642
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Lamb2
laminin, beta 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LAMB2 mRNA
CTD
PMID:23196670
NCBI chr 9:108,357,080...108,367,729
Ensembl chr 9:108,356,935...108,367,729
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Lancl1
LanC (bacterial lantibiotic synthetase component C)-like 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LANCL1 mRNA
CTD
PMID:23196670
NCBI chr 1:67,039,676...67,078,049
Ensembl chr 1:67,039,676...67,078,031
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Laptm4b
lysosomal-associated protein transmembrane 4B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LAPTM4B mRNA
CTD
PMID:23196670
NCBI chr15:34,238,279...34,284,448
Ensembl chr15:34,238,174...34,284,448
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Large1
LARGE xylosyl- and glucuronyltransferase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LARGE1 mRNA
CTD
PMID:32119087
NCBI chr 8:73,541,227...74,080,164
Ensembl chr 8:73,541,227...74,080,168
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Lbp
lipopolysaccharide binding protein
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LBP mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LBP mRNA
CTD
PMID:19692669 PMID:20959002 PMID:23196670
NCBI chr 2:158,148,413...158,174,772
Ensembl chr 2:158,148,413...158,174,772
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Lbr
lamin B receptor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LBR mRNA
CTD
PMID:23196670
NCBI chr 1:181,642,880...181,669,933
Ensembl chr 1:181,642,900...181,670,611
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Lcn2
lipocalin 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LCN2 mRNA
CTD
PMID:20959002
NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
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Ldha
lactate dehydrogenase A
increases expression decreases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LDHA mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LDHA mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LDHA mRNA]
CTD
PMID:23196670 PMID:29474705 PMID:30821169 PMID:34256052 PMID:37080397
NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051
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Ldhal6b
lactate dehydrogenase A-like 6B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LDHAL6B mRNA
CTD
PMID:23196670
NCBI chr17:5,467,598...5,469,042
Ensembl chr17:5,467,598...5,469,042
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Ldhb
lactate dehydrogenase B
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of LDHB mRNA
CTD
PMID:37080397
NCBI chr 6:142,435,975...142,453,683
Ensembl chr 6:142,435,975...142,453,683
G
Ldlr
low density lipoprotein receptor
increases expression increases response to substance
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LDLR mRNA LDLR gene mutant form results in increased susceptibility to 3,4,5,3',4'-pentachlorobiphenyl
CTD
PMID:23196670 PMID:29216392 PMID:35618242
NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
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Lef1
lymphoid enhancer binding factor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LEF1 mRNA
CTD
PMID:23196670
NCBI chr 3:130,903,972...131,018,006
Ensembl chr 3:130,904,120...131,018,005
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Lep
leptin
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of LEP protein
CTD
PMID:28973532
NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
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Letm2
leucine zipper-EF-hand containing transmembrane protein 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LETM2 mRNA
CTD
PMID:23196670
NCBI chr 8:26,068,494...26,088,005
Ensembl chr 8:26,068,506...26,087,598
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Lgals3
lectin, galactose binding, soluble 3
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LGALS3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LGALS3 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617
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Lgi4
leucine-rich repeat LGI family, member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LGI4 mRNA
CTD
PMID:23196670
NCBI chr 7:30,758,360...30,770,347
Ensembl chr 7:30,758,767...30,770,360
G
Lgmn
legumain
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LGMN mRNA
CTD
PMID:23196670
NCBI chr12:102,360,341...102,405,987
Ensembl chr12:102,360,343...102,406,072
G
Lhb
luteinizing hormone beta
multiple interactions
ISO
[AHR gene mutant form affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in increased secretion of LHB protein
CTD
PMID:34256052
NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
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Lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of LHPP mRNA
CTD
PMID:20702594
NCBI chr 7:132,212,344...132,308,149
Ensembl chr 7:132,212,367...132,308,149
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Lif
leukemia inhibitory factor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LIF mRNA
CTD
PMID:28351761 PMID:35618242
NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514
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Lifr
LIF receptor alpha
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LIFR mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr15:7,120,091...7,226,970
Ensembl chr15:7,120,095...7,226,970
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Lig1
ligase I, DNA, ATP-dependent
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LIG1 mRNA
CTD
PMID:23196670
NCBI chr 7:13,011,101...13,045,351
Ensembl chr 7:13,011,239...13,045,350
G
Limk1
LIM domain kinase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LIMK1 mRNA
CTD
PMID:23196670
NCBI chr 5:134,684,893...134,718,713
Ensembl chr 5:134,684,893...134,717,452
G
Limk2
LIM domain kinase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LIMK2 mRNA
CTD
PMID:19692669
NCBI chr11:3,293,297...3,359,238
Ensembl chr11:3,294,256...3,359,189
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Lipa
lysosomal acid lipase A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LIP1 mRNA
CTD
PMID:23196670
NCBI chr19:34,469,716...34,504,874
Ensembl chr19:34,469,718...34,504,874
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Lipe
lipase, hormone sensitive
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LIPE mRNA
CTD
PMID:23196670
NCBI chr 7:25,078,952...25,097,911
Ensembl chr 7:25,078,952...25,098,135
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Lmcd1
LIM and cysteine-rich domains 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LMCD1 mRNA
CTD
PMID:23196670
NCBI chr 6:112,250,747...112,307,384
Ensembl chr 6:112,250,719...112,307,386
G
Lmnb1
lamin B1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LMNB1 mRNA
CTD
PMID:23196670
NCBI chr18:56,840,885...56,886,496
Ensembl chr18:56,840,885...56,886,496
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Lmo4
LIM domain only 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LMO4 mRNA
CTD
PMID:23196670
NCBI chr 3:143,894,291...143,911,016
Ensembl chr 3:143,894,291...143,910,981
G
Lmo7
LIM domain only 7
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LMO7 mRNA
CTD
PMID:23196670
NCBI chr14:101,967,353...102,172,144
Ensembl chr14:101,967,386...102,172,146
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Lnpep
leucyl/cystinyl aminopeptidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LNPEP mRNA
CTD
PMID:23196670
NCBI chr17:17,747,985...17,846,303
Ensembl chr17:17,741,672...17,845,312
G
Lox
lysyl oxidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LOX mRNA
CTD
PMID:23196670
NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939
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Loxl1
lysyl oxidase-like 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LOXL1 mRNA
CTD
PMID:20959002
NCBI chr 9:58,195,006...58,220,495
Ensembl chr 9:58,195,021...58,220,469
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Lpar1
lysophosphatidic acid receptor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LPAR1 mRNA
CTD
PMID:23196670
NCBI chr 4:58,435,252...58,554,601
Ensembl chr 4:58,435,255...58,553,898
G
Lpin1
lipin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LPIN1 mRNA
CTD
PMID:23196670
NCBI chr12:16,585,670...16,697,020
Ensembl chr12:16,585,670...16,696,967
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Lpin2
lipin 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LPIN2 mRNA
CTD
PMID:23994337
NCBI chr17:71,490,527...71,556,813
Ensembl chr17:71,489,555...71,556,812
G
Lpl
lipoprotein lipase
increases expression decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LPL mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LPL mRNA
CTD
PMID:20959002 PMID:23196670 PMID:29216392 PMID:29947894 PMID:32119087
NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
G
Lpo
lactoperoxidase
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LPO mRNA]
CTD
PMID:34256052
NCBI chr11:87,697,254...87,716,750
Ensembl chr11:87,697,254...87,719,115
G
Lrfn1
leucine rich repeat and fibronectin type III domain containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LRFN1 mRNA
CTD
PMID:23146750
NCBI chr 7:28,151,194...28,167,667
Ensembl chr 7:28,151,405...28,167,667
G
Lrfn3
leucine rich repeat and fibronectin type III domain containing 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LRFN3 mRNA
CTD
PMID:32119087
NCBI chr 7:30,054,939...30,062,197
Ensembl chr 7:30,054,914...30,062,197
G
Lrp1
low density lipoprotein receptor-related protein 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of LRP1 mRNA
CTD
PMID:37080397
NCBI chr10:127,374,026...127,457,158
Ensembl chr10:127,374,030...127,457,017
G
Lrp2
low density lipoprotein receptor-related protein 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LRP2 mRNA
CTD
PMID:23994337
NCBI chr 2:69,254,679...69,416,373
Ensembl chr 2:69,254,684...69,416,409
G
Lrp4
low density lipoprotein receptor-related protein 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LRP4 mRNA
CTD
PMID:23196670
NCBI chr 2:91,287,794...91,344,246
Ensembl chr 2:91,287,856...91,344,124
G
Lrrfip1
leucine rich repeat (in FLII) interacting protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LRRFIP1 mRNA
CTD
PMID:23196670
NCBI chr 1:90,924,652...91,056,666
Ensembl chr 1:90,926,459...91,056,666
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Lss
lanosterol synthase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LSS mRNA
CTD
PMID:23196670
NCBI chr10:76,367,303...76,392,973
Ensembl chr10:76,367,422...76,392,972
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Ltb
lymphotoxin B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LTB mRNA
CTD
PMID:28351761
NCBI chr17:35,413,483...35,415,281
Ensembl chr17:35,413,415...35,415,296
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Ltb4r2
leukotriene B4 receptor 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LTB4R2 mRNA
CTD
PMID:23146750
NCBI chr14:55,995,379...56,001,523
Ensembl chr14:55,998,885...56,002,595
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Ltbp1
latent transforming growth factor beta binding protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LTBP1 mRNA
CTD
PMID:23196670
NCBI chr17:75,312,475...75,699,507
Ensembl chr17:75,312,563...75,699,507
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Ltf
lactotransferrin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LTF mRNA
CTD
PMID:32119087
NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835
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Lyar
Ly1 antibody reactive clone
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LYAR mRNA
CTD
PMID:23196670
NCBI chr 5:38,377,815...38,391,650
Ensembl chr 5:38,377,814...38,391,650
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Lyn
LYN proto-oncogene, Src family tyrosine kinase
affects expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of LYN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LYN mRNA
CTD
PMID:20702594 PMID:23196670
NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122
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Lypd1
Ly6/Plaur domain containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LYPD1 mRNA
CTD
PMID:23196670
NCBI chr 1:125,795,359...125,841,134
Ensembl chr 1:125,795,359...125,840,838
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Lypla1
lysophospholipase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LYPLA1 mRNA
CTD
PMID:23196670
NCBI chr 1:4,878,046...4,916,958
Ensembl chr 1:4,878,011...4,918,633
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Lyz2
lysozyme 2
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LYZ mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LYZ mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
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Lyzl1
lysozyme-like 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of LYZL1 mRNA
CTD
PMID:23994337
NCBI chr18:4,165,862...4,182,232
Ensembl chr18:4,165,832...4,182,232
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Mab21l3
mab-21-like 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MAB21L3 mRNA
CTD
PMID:32119087
NCBI chr 3:101,720,392...101,743,601
Ensembl chr 3:101,720,392...101,756,275
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Maf
MAF bZIP transcription factor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MAF mRNA
CTD
PMID:23196670
NCBI chr 8:116,429,992...116,433,633
Ensembl chr 8:116,409,681...116,434,533
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Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MAFF mRNA
CTD
PMID:19692669
NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276
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Magee1
MAGE family member E1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MAGEE1 mRNA
CTD
PMID:23146750
NCBI chr X:104,163,984...104,167,567
Ensembl chr X:104,163,984...104,167,533
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Malt1
MALT1 paracaspase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MALT1 mRNA
CTD
PMID:32119087
NCBI chr18:65,564,010...65,612,138
Ensembl chr18:65,564,009...65,612,138
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Maoa
monoamine oxidase A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MAOA mRNA
CTD
PMID:19692669
NCBI chr X:16,485,937...16,554,051
Ensembl chr X:16,485,937...16,554,057
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Maob
monoamine oxidase B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MAOB mRNA
CTD
PMID:19692669
NCBI chr X:16,575,520...16,683,605
Ensembl chr X:16,575,521...16,683,605
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Mapk1
mitogen-activated protein kinase 1
increases phosphorylation multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of MAPK1 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK1 protein; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD
PMID:19751709 PMID:20406653 PMID:20840854 PMID:29329451
NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
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Mapk3
mitogen-activated protein kinase 3
increases phosphorylation multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of MAPK3 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK3 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK3 protein; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD
PMID:19751709 PMID:20406653 PMID:20840854 PMID:29329451
NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
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Mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MAPKAPK3 mRNA
CTD
PMID:23196670
NCBI chr 9:107,132,125...107,167,082
Ensembl chr 9:107,132,126...107,167,076
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Mapkapk5
MAP kinase-activated protein kinase 5
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MAPKAPK5 mRNA
CTD
PMID:23994337
NCBI chr 5:121,663,114...121,683,955
Ensembl chr 5:121,663,101...121,683,968
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Marcks
myristoylated alanine rich protein kinase C substrate
decreases expression multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MARCKS mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MARCKS mRNA]
CTD
PMID:19692669 PMID:34256052
NCBI chr10:37,009,239...37,014,922
Ensembl chr10:37,009,371...37,014,916
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Marco
macrophage receptor with collagenous structure
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MARCO mRNA
CTD
PMID:23146750
NCBI chr 1:120,402,267...120,432,753
Ensembl chr 1:120,402,267...120,432,753
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Masp1
MBL associated serine protease 1
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MASP1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MASP1 mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr16:23,261,778...23,340,127
Ensembl chr16:23,268,167...23,339,565
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Mat2b
methionine adenosyltransferase 2 non-catalytic beta subunit methionine
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MAT2B mRNA
CTD
PMID:23994337
NCBI chr11:40,570,141...40,586,030
Ensembl chr11:40,570,141...40,586,030
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Mavs
mitochondrial antiviral signaling protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MAVS mRNA
CTD
PMID:32119087
NCBI chr 2:131,075,445...131,089,945
Ensembl chr 2:131,075,983...131,089,945
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Mb21d2
Mab-21 domain containing 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MB21D2 mRNA
CTD
PMID:29947894
NCBI chr16:28,644,928...28,748,802
Ensembl chr16:28,644,928...28,748,425
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Mbl2
mannose-binding lectin (protein C) 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MBL2 mRNA
CTD
PMID:19692669
NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087
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Mc2r
melanocortin 2 receptor
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MC2R mRNA [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of MC2R mRNA; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of MC2R mRNA
CTD
PMID:25765474
NCBI chr18:68,539,970...68,562,391
Ensembl chr18:68,539,978...68,562,391
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Mcam
melanoma cell adhesion molecule
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MCAM mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 9:44,045,958...44,054,024
Ensembl chr 9:44,045,766...44,054,024
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Mccc1
methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MCCC1 mRNA
CTD
PMID:19692669
NCBI chr 3:36,009,584...36,054,843
Ensembl chr 3:36,013,461...36,054,827
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Mcf2l
mcf.2 transforming sequence-like
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MCF2L mRNA
CTD
PMID:32119087
NCBI chr 8:12,923,806...13,070,502
Ensembl chr 8:12,923,806...13,070,905
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Mcm3ap
minichromosome maintenance complex component 3 associated protein
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MCM3AP mRNA
CTD
PMID:23994337
NCBI chr10:76,304,736...76,351,693
Ensembl chr10:76,304,761...76,351,691
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Mdfi
MyoD family inhibitor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MDFI mRNA
CTD
PMID:23146750
NCBI chr17:48,126,253...48,145,616
Ensembl chr17:48,126,253...48,145,616
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Mdm2
transformed mouse 3T3 cell double minute 2
multiple interactions increases phosphorylation
ISO
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of MDM2 protein]; MDM2 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased phosphorylation of FOXO3 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of MDM2 protein
CTD
PMID:19751709 PMID:20840854
NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
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Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ME1 mRNA
CTD
PMID:20959002
NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006
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Me3
malic enzyme 3, NADP(+)-dependent, mitochondrial
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ME3 mRNA
CTD
PMID:23146750
NCBI chr 7:89,281,492...89,503,423
Ensembl chr 7:89,281,600...89,503,567
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Med1
mediator complex subunit 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of MED1 mRNA
CTD
PMID:20702594
NCBI chr11:98,042,980...98,084,121
Ensembl chr11:98,042,980...98,084,119
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Met
met proto-oncogene
increases expression decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MET mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MET mRNA
CTD
PMID:23146750 PMID:23196670 PMID:37080397
NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
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Mfap4
microfibrillar-associated protein 4
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MFAP4 mRNA
CTD
PMID:23994337
NCBI chr11:61,376,257...61,379,536
Ensembl chr11:61,376,257...61,379,726
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Mfap5
microfibrillar associated protein 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MFAP5 mRNA
CTD
PMID:32119087
NCBI chr 6:122,490,543...122,506,249
Ensembl chr 6:122,482,804...122,506,249
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Mgat1
mannoside acetylglucosaminyltransferase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MGAT1 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr11:49,135,018...49,153,854
Ensembl chr11:49,135,018...49,153,857
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Mgat3
mannoside acetylglucosaminyltransferase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MGAT3 mRNA
CTD
PMID:23196670
NCBI chr15:80,057,852...80,099,720
Ensembl chr15:80,057,922...80,099,720
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Mgll
monoglyceride lipase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MGLL mRNA
CTD
PMID:23196670
NCBI chr 6:88,701,397...88,805,342
Ensembl chr 6:88,701,394...88,805,342
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Mgp
matrix Gla protein
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MGP mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MGP mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 6:136,849,433...136,852,821
Ensembl chr 6:136,849,433...136,852,821
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Mgst1
microsomal glutathione S-transferase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MGST1 mRNA
CTD
PMID:21703328
NCBI chr 6:138,117,525...138,133,753
Ensembl chr 6:138,117,314...138,133,753
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Mgst2
microsomal glutathione S-transferase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MGST2 mRNA
CTD
PMID:23146750
NCBI chr 3:51,544,179...51,590,096
Ensembl chr 3:51,567,781...51,590,098
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Mgst3
microsomal glutathione S-transferase 3
multiple interactions decreases expression
ISO EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of MGST3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MGST3 mRNA
CTD
PMID:16984957 PMID:18723825 PMID:19692669 PMID:20959002
NCBI chr 1:167,199,535...167,221,410
Ensembl chr 1:167,199,535...167,221,410
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Mical2
microtubule associated monooxygenase, calponin and LIM domain containing 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MICAL2 mRNA
CTD
PMID:23196670
NCBI chr 7:111,825,032...112,012,311
Ensembl chr 7:111,825,063...112,012,313
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Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MID1IP1 mRNA
CTD
PMID:23146750
NCBI chr X:10,583,604...10,585,941
Ensembl chr X:10,581,252...10,585,929
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Mios
meiosis regulator for oocyte development
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MIOS mRNA
CTD
PMID:23994337
NCBI chr 6:8,209,111...8,240,573
Ensembl chr 6:8,209,222...8,236,274
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Mkln1
muskelin 1, intracellular mediator containing kelch motifs
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MKLN1 mRNA
CTD
PMID:32119087
NCBI chr 6:31,333,833...31,493,744
Ensembl chr 6:31,375,670...31,493,746
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Mmd
monocyte to macrophage differentiation-associated
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MMD mRNA
CTD
PMID:23196670
NCBI chr11:90,078,513...90,169,399
Ensembl chr11:90,140,282...90,169,415
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Mme
membrane metallo endopeptidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MME mRNA
CTD
PMID:23196670
NCBI chr 3:63,202,632...63,291,134
Ensembl chr 3:63,148,958...63,293,451
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Mmp11
matrix metallopeptidase 11
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MMP11 mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr10:75,759,056...75,768,336
Ensembl chr10:75,759,056...75,772,330
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Mmp12
matrix metallopeptidase 12
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MMP12 mRNA
CTD
PMID:20959002
NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
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Mmp14
matrix metallopeptidase 14 (membrane-inserted)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MMP14 mRNA
CTD
PMID:23196670
NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821
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Mmp1b
matrix metallopeptidase 1b (interstitial collagenase)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MMP1 mRNA
CTD
PMID:35618242
NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
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Mmp2
matrix metallopeptidase 2
increases expression increases secretion
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MMP2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of MMP2 protein
CTD
PMID:27663891 PMID:29947894 PMID:35618242
NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
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Mmp23
matrix metallopeptidase 23
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MMP23 mRNA
CTD
PMID:23994337
NCBI chr 4:155,735,111...155,738,982
Ensembl chr 4:155,735,112...155,737,841
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Mmp3
matrix metallopeptidase 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MMP3 mRNA
CTD
PMID:35618242
NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
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Mmp9
matrix metallopeptidase 9
affects expression increases secretion increases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of MMP9 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of MMP9 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MMP9 mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of MMP9 protein]
CTD
PMID:21703328 PMID:27663891 PMID:28973532
NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
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Mogat1
monoacylglycerol O-acyltransferase 1
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of MOGAT1 mRNA
CTD
PMID:28973532
NCBI chr 1:78,487,697...78,597,882
Ensembl chr 1:78,487,628...78,514,810
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Mpo
myeloperoxidase
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MPO mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MPO mRNA]
CTD
PMID:34256052
NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
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Mpp7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MPP7 mRNA
CTD
PMID:32119087
NCBI chr18:7,347,962...7,627,017
Ensembl chr18:7,347,959...7,626,866
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Mpped2
metallophosphoesterase domain containing 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MPPED2 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 2:106,523,526...106,699,684
Ensembl chr 2:106,523,614...106,698,701
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Mrpl37
mitochondrial ribosomal protein L37
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MRPL37 mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr 4:106,913,071...106,924,063
Ensembl chr 4:106,913,071...106,924,065
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Mrps24
mitochondrial ribosomal protein S24
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MRPS24 mRNA
CTD
PMID:23994337
NCBI chr11:5,653,982...5,657,701
Ensembl chr11:5,653,983...5,665,680
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Ms4a14
membrane-spanning 4-domains, subfamily A, member 14
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MS4A14 mRNA
CTD
PMID:32119087
NCBI chr19:11,278,613...11,293,239
Ensembl chr19:11,278,613...11,291,818
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Ms4a4a
membrane-spanning 4-domains, subfamily A, member 4A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MS4A4A mRNA
CTD
PMID:23146750
NCBI chr19:11,352,827...11,370,682
Ensembl chr19:11,352,887...11,370,154
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Ms4a6c
membrane-spanning 4-domains, subfamily A, member 6C
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MS4A6A mRNA
CTD
PMID:23146750
NCBI chr19:11,446,718...11,464,433
Ensembl chr19:11,446,730...11,459,556
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Ms4a7
membrane-spanning 4-domains, subfamily A, member 7
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MS4A7 mRNA
CTD
PMID:32119087
NCBI chr19:11,298,403...11,313,510
Ensembl chr19:11,298,403...11,313,510
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Msmo1
methylsterol monoxygenase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MSMO1 mRNA
CTD
PMID:23196670
NCBI chr 8:65,171,157...65,186,822
Ensembl chr 8:65,171,173...65,186,826
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Msr1
macrophage scavenger receptor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MSR1 mRNA
CTD
PMID:23146750
NCBI chr 8:39,996,284...40,095,790
Ensembl chr 8:40,034,726...40,095,714
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Mt1
metallothionein 1
multiple interactions affects response to substance increases expression
EXP ISO
[MT1 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which affects the expression of CYP1A2 mRNA; [MT1 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased abundance of Copper; [MT1 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased abundance of Manganese; [MT1 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased abundance of Zinc 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MT1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MT1A mRNA
CTD
PMID:26410179 PMID:26660635 PMID:26770886 PMID:26967026
NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955
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Mt2
metallothionein 2
increases expression multiple interactions affects response to substance
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MT2A mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MT2A protein [MT2 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which affects the expression of CYP1A2 mRNA; [MT2 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased abundance of Copper; [MT2 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased abundance of Manganese; [MT2 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which results in decreased abundance of Zinc
CTD
PMID:23527585 PMID:26410179 PMID:26770886 PMID:26967026
NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
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Mthfr
methylenetetrahydrofolate reductase
multiple interactions increases expression
ISO
AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MTHFR mRNA]
CTD
PMID:34256052
NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008
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Mtmr7
myotubularin related protein 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MTMR7 mRNA
CTD
PMID:20959002
NCBI chr 8:41,003,184...41,088,210
Ensembl chr 8:41,004,136...41,087,840
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Mtor
mechanistic target of rapamycin kinase
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of MTOR mRNA
CTD
PMID:37080397
NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
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Mttp
microsomal triglyceride transfer protein
multiple interactions decreases expression
EXP ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of MTTP mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MTTP protein
CTD
PMID:26693162 PMID:28973532
NCBI chr 3:137,795,616...137,849,179
Ensembl chr 3:137,795,615...137,850,729
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Mvd
mevalonate (diphospho) decarboxylase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MVD mRNA
CTD
PMID:23196670
NCBI chr 8:123,160,335...123,170,161
Ensembl chr 8:123,160,340...123,170,161
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Mx1
MX dynamin-like GTPase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MX1 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr16:97,248,235...97,264,106
Ensembl chr16:97,248,235...97,264,107
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Mxra8
matrix-remodelling associated 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MXRA8 mRNA
CTD
PMID:23196670
NCBI chr 4:155,924,137...155,928,559
Ensembl chr 4:155,924,137...155,928,545
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Myh10
myosin, heavy polypeptide 10, non-muscle
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MYH10 mRNA
CTD
PMID:23196670
NCBI chr11:68,581,228...68,707,451
Ensembl chr11:68,582,385...68,707,458
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Myl1
myosin, light polypeptide 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MYL1 mRNA
CTD
PMID:32119087
NCBI chr 1:66,963,454...66,987,091
Ensembl chr 1:66,963,454...66,984,563
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Myl9
myosin, light polypeptide 9, regulatory
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of MYL9 mRNA
CTD
PMID:19692669
NCBI chr 2:156,617,373...156,623,578
Ensembl chr 2:156,617,340...156,623,578
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Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MYLPF mRNA
CTD
PMID:32119087
NCBI chr 7:126,808,071...126,813,459
Ensembl chr 7:126,808,062...126,813,470
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Myof
myoferlin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MYOF mRNA
CTD
PMID:19692669
NCBI chr19:37,887,484...38,032,025
Ensembl chr19:37,887,484...38,032,025
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Myoz2
myozenin 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MYOZ2 mRNA
CTD
PMID:23994337
NCBI chr 3:122,799,855...122,828,649
Ensembl chr 3:122,799,855...122,828,664
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Naaa
N-acylethanolamine acid amidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NAAA mRNA
CTD
PMID:23196670
NCBI chr 5:92,405,519...92,426,040
Ensembl chr 5:92,405,518...92,426,029
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Nampt
nicotinamide phosphoribosyltransferase
multiple interactions decreases expression increases expression
ISO EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of NAMPT mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NAMPT mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NAMPT mRNA
CTD
PMID:16984957 PMID:20959002 PMID:37080397
NCBI chr12:32,870,334...32,903,368
Ensembl chr12:32,869,544...32,903,348
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Nat8
N-acetyltransferase 8 (GCN5-related)
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of NAT8 mRNA
CTD
PMID:30744511
NCBI chr 6:85,807,369...85,813,839
Ensembl chr 6:85,807,370...85,809,064
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Nat8f2
N-acetyltransferase 8 (GCN5-related) family member 2
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of NAT8F2 mRNA
CTD
PMID:30744511
NCBI chr 6:85,842,404...85,846,119
Ensembl chr 6:85,842,404...85,846,140
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Nav2
neuron navigator 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NAV2 mRNA
CTD
PMID:32119087
NCBI chr 7:48,608,796...49,259,838
Ensembl chr 7:48,558,464...49,259,838
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Ncam1
neural cell adhesion molecule 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NCAM1 mRNA
CTD
PMID:23196670
NCBI chr 9:49,413,434...49,710,909
Ensembl chr 9:49,413,436...49,710,225
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Ncf1
neutrophil cytosolic factor 1
multiple interactions increases localization increases expression increases phosphorylation
ISO
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [NCF1 protein binds to CYBB protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [NCF1 protein modified form binds to CYBB protein]; acetovanillone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of NCF1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased localization of NCF1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NCF1 mRNA
CTD
PMID:20299304 PMID:23146750 PMID:30821169
NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
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Ncf4
neutrophil cytosolic factor 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NCF4 mRNA
CTD
PMID:30821169
NCBI chr15:78,128,324...78,146,782
Ensembl chr15:78,129,001...78,146,780
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Ndrg4
N-myc downstream regulated gene 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NDRG4 mRNA
CTD
PMID:23196670
NCBI chr 8:96,403,602...96,441,584
Ensembl chr 8:96,403,608...96,441,747
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Ndufb9
NADH:ubiquinone oxidoreductase subunit B9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NDUFB9 mRNA
CTD
PMID:19692669
NCBI chr15:58,805,650...58,811,365
Ensembl chr15:58,805,605...58,811,337
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Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NEDD4L mRNA
CTD
PMID:23196670
NCBI chr18:65,017,551...65,350,888
Ensembl chr18:65,020,776...65,350,899
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Nefh
neurofilament, heavy polypeptide
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NEFH mRNA
CTD
PMID:23146750
NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
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Neurl3
neuralized E3 ubiquitin protein ligase 3
increases expression affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NEURL3 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of LINCR mRNA
CTD
PMID:19692669 PMID:20702594
NCBI chr 1:36,303,683...36,313,755
Ensembl chr 1:36,303,678...36,313,760
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Nfe2l2
nuclear factor, erythroid derived 2, like 2
increases expression multiple interactions affects expression decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NFE2L2 mRNA [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NFE2L2 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of NFE2L2 mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [perfluorooctane sulfonic acid results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 protein]]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 protein
CTD
PMID:23196670 PMID:24378064 PMID:26770886 PMID:30768972 PMID:31563530 PMID:33096110 PMID:37080397 PMID:37598416 More...
NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
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Nfia
nuclear factor I/A
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFIA mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NFIA mRNA
CTD
PMID:20959002 PMID:32119087
NCBI chr 4:97,469,534...98,007,113
Ensembl chr 4:97,660,971...98,007,111
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Nfix
nuclear factor I/X
affects expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of NFIX mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFIX mRNA
CTD
PMID:20959002 PMID:21703328
NCBI chr 8:85,431,341...85,527,086
Ensembl chr 8:85,426,505...85,526,973
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Ngf
nerve growth factor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NGF mRNA
CTD
PMID:35618242
NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
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Ngfr
nerve growth factor receptor (TNFR superfamily, member 16)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NGFR mRNA
CTD
PMID:23196670
NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561
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Nherf1
NHERF family PDZ scaffold protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NHERF1 mRNA
CTD
PMID:23196670
NCBI chr11:115,054,138...115,072,009
Ensembl chr11:115,054,167...115,072,007
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Nid2
nidogen 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NID2 mRNA
CTD
PMID:23196670
NCBI chr14:19,801,325...19,861,855
Ensembl chr14:19,801,333...19,861,855
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Nipal2
NIPA-like domain containing 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NIPAL2 mRNA
CTD
PMID:20959002
NCBI chr15:34,572,942...34,679,739
Ensembl chr15:34,572,945...34,679,358
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Nkx6-1
NK6 homeobox 1
increases expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NKX6-1 mRNA 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of NKX6-1 mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NKX6-1 mRNA]
CTD
PMID:30312631
NCBI chr 5:101,807,050...101,812,577
Ensembl chr 5:101,806,005...101,812,862
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Nmt2
N-myristoyltransferase 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NMT2 mRNA
CTD
PMID:23196670
NCBI chr 2:3,285,249...3,329,914
Ensembl chr 2:3,285,249...3,329,914
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Nol3
nucleolar protein 3 (apoptosis repressor with CARD domain)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NOL3 mRNA
CTD
PMID:23196670
NCBI chr 8:106,002,777...106,008,571
Ensembl chr 8:106,002,772...106,008,571
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Nop58
NOP58 ribonucleoprotein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NOL5 mRNA
CTD
PMID:23196670
NCBI chr 1:59,724,165...59,751,352
Ensembl chr 1:59,724,130...59,758,203
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Nos2
nitric oxide synthase 2, inducible
affects expression multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of NOS2 mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NOS2 mRNA]
CTD
PMID:21703328 PMID:34256052
NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
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Nos3
nitric oxide synthase 3, endothelial cell
multiple interactions
ISO
[Estradiol co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of NOS3 mRNA
CTD
PMID:21513769
NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
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Notch1
notch 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NOTCH1 mRNA
CTD
PMID:18042819 PMID:20702594 PMID:23994337
NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675
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Nox1
NADPH oxidase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NOX1 mRNA
CTD
PMID:32119087
NCBI chr X:132,987,170...133,038,455
Ensembl chr X:132,987,170...133,122,705
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Nox4
NADPH oxidase 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NOX4 mRNA
CTD
PMID:32119087 PMID:35618242
NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918
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Nphp1
nephronophthisis 1 (juvenile) homolog (human)
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NPHP1 mRNA
CTD
PMID:23994337
NCBI chr 2:127,582,652...127,630,833
Ensembl chr 2:127,582,652...127,630,817
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Npl
N-acetylneuraminate pyruvate lyase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NPL mRNA
CTD
PMID:23196670
NCBI chr 1:153,378,762...153,425,460
Ensembl chr 1:153,378,761...153,425,791
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Nppb
natriuretic peptide type B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NPPB mRNA
CTD
PMID:23196670
NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
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Npr1
natriuretic peptide receptor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NPR1 mRNA
CTD
PMID:23196670
NCBI chr 3:90,357,898...90,373,235
Ensembl chr 3:90,357,898...90,373,173
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Npr3
natriuretic peptide receptor 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NPR3 mRNA
CTD
PMID:23196670
NCBI chr15:11,839,982...11,907,287
Ensembl chr15:11,839,982...11,907,373
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Nptx1
neuronal pentraxin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NPTX1 mRNA
CTD
PMID:22262711
NCBI chr11:119,429,545...119,438,646
Ensembl chr11:119,429,545...119,438,579
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Nptxr
neuronal pentraxin receptor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NPTXR mRNA
CTD
PMID:23196670
NCBI chr15:79,670,552...79,688,910
Ensembl chr15:79,670,552...79,688,967
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Npy4r
neuropeptide Y receptor Y4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NPY4R mRNA
CTD
PMID:32119087
NCBI chr14:33,867,603...33,874,376
Ensembl chr14:33,865,949...33,874,446
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Nqo1
NAD(P)H dehydrogenase, quinone 1
increases expression multiple interactions decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NQO1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of NQO1 mRNA; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 protein]]; CAV1 gene mutant form promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 protein]; Sunphenon promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA]; Sunphenon promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 protein] [Lipopolysaccharides co-treated with IFNG protein] promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA] AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 protein
CTD
PMID:17627975 PMID:18042819 PMID:19692669 PMID:20702594 PMID:20959002 PMID:22262711 PMID:23196670 PMID:23994337 PMID:24378064 PMID:24709675 PMID:26770886 PMID:28163111 PMID:30768972 PMID:32119087 PMID:33096110 PMID:34256052 PMID:37080397 PMID:37598416 More...
NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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Nr0b2
nuclear receptor subfamily 0, group B, member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NR0B2 mRNA
CTD
PMID:20959002
NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847
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Nr1h4
nuclear receptor subfamily 1, group H, member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NR1H4 mRNA
CTD
PMID:19692669
NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
decreases expression multiple interactions increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NR1I2 mRNA 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in decreased expression of NR1I2 mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NR1I2 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NR1I2 mRNA
CTD
PMID:30312631 PMID:37080397
NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
increases expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NR1I3 mRNA [aroclor 1260 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of NR1I3 mRNA
CTD
PMID:17627975 PMID:30312631
NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of NR3C1 mRNA
CTD
PMID:37080397
NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of NR4A1 mRNA]
CTD
PMID:30312631
NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
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Nr4a3
nuclear receptor subfamily 4, group A, member 3
multiple interactions increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of NR4A3 mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NR4A3 mRNA]
CTD
PMID:30312631
NCBI chr 4:48,045,098...48,086,446
Ensembl chr 4:48,045,153...48,086,447
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Nrg1
neuregulin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NRG1 mRNA
CTD
PMID:19692669 PMID:20959002 PMID:23196670
NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825 Ensembl chr 8:32,304,579...33,374,825
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Nrgn
neurogranin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NRGN mRNA
CTD
PMID:23196670
NCBI chr 9:37,455,789...37,464,041
Ensembl chr 9:37,455,788...37,464,200
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Nrm
nurim (nuclear envelope membrane protein)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NRM mRNA
CTD
PMID:23196670
NCBI chr17:36,171,987...36,176,292
Ensembl chr17:36,172,210...36,176,294
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Nrp2
neuropilin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NRP2 mRNA
CTD
PMID:23146750
NCBI chr 1:62,742,476...62,857,851
Ensembl chr 1:62,742,444...62,857,854
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Nsdhl
NAD(P) dependent steroid dehydrogenase-like
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NSDHL mRNA
CTD
PMID:23196670
NCBI chr X:71,962,127...72,002,134
Ensembl chr X:71,962,163...72,002,120
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Nsmf
NMDA receptor synaptonuclear signaling and neuronal migration factor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NSMF mRNA
CTD
PMID:32119087
NCBI chr 2:24,944,370...24,952,893
Ensembl chr 2:24,944,367...24,952,893
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Nt5e
5' nucleotidase, ecto
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NT5E mRNA
CTD
PMID:23196670
NCBI chr 9:88,209,662...88,254,142
Ensembl chr 9:88,209,250...88,254,145
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Ntf3
neurotrophin 3
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of NTF3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NTF3 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 6:126,078,375...126,143,703
Ensembl chr 6:126,078,375...126,143,873
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Ntn4
netrin 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NTN4 mRNA
CTD
PMID:29947894
NCBI chr10:93,476,911...93,581,834
Ensembl chr10:93,476,543...93,583,069
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Ntrk1
neurotrophic tyrosine kinase, receptor, type 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NTRK1 mRNA
CTD
PMID:20959002
NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469
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Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NTRK2 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784
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Nuf2
NUF2, NDC80 kinetochore complex component
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NUF2 mRNA
CTD
PMID:23196670
NCBI chr 1:169,325,503...169,359,033
Ensembl chr 1:169,325,503...169,359,033
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Nupr1
nuclear protein transcription regulator 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NUPR1 mRNA
CTD
PMID:19692669
NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033
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Nxph4
neurexophilin 4
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NXPH4 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NXPH4 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr10:127,361,342...127,370,428
Ensembl chr10:127,361,342...127,370,428
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Oas1g
2'-5' oligoadenylate synthetase 1G
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OAS1 mRNA
CTD
PMID:23196670
NCBI chr 5:121,014,205...121,025,676
Ensembl chr 5:121,014,205...121,025,676
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Oasl1
2'-5' oligoadenylate synthetase-like 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OASL1 mRNA
CTD
PMID:23196670
NCBI chr 5:115,061,236...115,075,970
Ensembl chr 5:115,061,299...115,075,974
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Ocln
occludin
multiple interactions decreases expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [TJP1 protein binds to OCLN protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of OCLN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN protein
CTD
PMID:20064788 PMID:20299304 PMID:23196670 PMID:37598416
NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
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Olfml1
olfactomedin-like 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OLFML1 mRNA
CTD
PMID:23196670
NCBI chr 7:107,166,640...107,190,572
Ensembl chr 7:107,166,653...107,190,301
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Oplah
5-oxoprolinase (ATP-hydrolysing)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OPLAH mRNA
CTD
PMID:23196670
NCBI chr15:76,180,803...76,215,381
Ensembl chr15:76,180,801...76,212,215
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Optn
optineurin
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OPTN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of OPTN mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 2:5,023,902...5,069,210
Ensembl chr 2:5,025,453...5,068,862
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Or10a5
olfactory receptor family 10 subfamily A member 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of OR10A5 mRNA
CTD
PMID:23196670
NCBI chr 7:106,635,343...106,636,317
Ensembl chr 7:106,630,381...106,640,201
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Or14c39
olfactory receptor family 14 subfamily C member 39
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OR14C39B mRNA
CTD
PMID:23196670
NCBI chr 7:86,337,549...86,344,592
Ensembl chr 7:86,337,538...86,346,715
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Or14j3
olfactory receptor family 14 subfamily J member 3
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of OR14J3 mRNA
CTD
PMID:20702594
NCBI chr17:37,900,304...37,901,242
Ensembl chr17:37,900,124...37,903,634
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Or2a51
olfactory receptor family 2 subfamily A member 51
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of OR2A51 mRNA
CTD
PMID:23196670
NCBI chr 6:43,178,580...43,179,521
Ensembl chr 6:43,174,080...43,180,563
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Or2d2b
olfactory receptor family 2 subfamily D member 2B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of OR2D2 mRNA
CTD
PMID:23196670
NCBI chr 7:106,705,119...106,706,066
Ensembl chr 7:106,702,955...106,709,576
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Orc1
origin recognition complex, subunit 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ORC1 mRNA
CTD
PMID:23196670
NCBI chr 4:108,436,651...108,472,030
Ensembl chr 4:108,436,620...108,472,030
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Orm1
orosomucoid 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ORM1 mRNA
CTD
PMID:21703328
NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400
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Osmr
oncostatin M receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OSMR mRNA
CTD
PMID:23196670
NCBI chr15:6,843,049...6,904,434
Ensembl chr15:6,843,058...6,904,450
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Osr2
odd-skipped related 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OSR2 mRNA
CTD
PMID:23196670
NCBI chr15:35,296,244...35,303,451
Ensembl chr15:35,296,244...35,303,451
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Otc
ornithine transcarbamylase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OTC mRNA
CTD
PMID:20959002
NCBI chr X:10,118,584...10,187,275
Ensembl chr X:10,118,544...10,187,263
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Otop1
otopetrin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of OTOP1 mRNA
CTD
PMID:23196670
NCBI chr 5:38,434,748...38,461,560
Ensembl chr 5:38,433,316...38,461,552
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P3h2
prolyl 3-hydroxylase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of P3H2 mRNA
CTD
PMID:23146750
NCBI chr16:25,778,034...25,924,563
Ensembl chr16:25,778,038...25,924,534
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P4ha3
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of P4HA3 mRNA
CTD
PMID:23196670
NCBI chr 7:99,934,637...99,968,908
Ensembl chr 7:99,934,727...99,968,906
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Pak1
p21 (RAC1) activated kinase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PAK1 mRNA
CTD
PMID:23196670
NCBI chr 7:97,437,748...97,561,588
Ensembl chr 7:97,437,748...97,561,588
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Palm
paralemmin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PALM mRNA
CTD
PMID:23196670
NCBI chr10:79,629,406...79,656,749
Ensembl chr10:79,629,406...79,656,730
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Pappa2
pappalysin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PAPPA2 mRNA
CTD
PMID:32119087
NCBI chr 1:158,539,297...158,788,019
Ensembl chr 1:158,539,297...158,808,060
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Paqr8
progestin and adipoQ receptor family member VIII
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PAQR8 mRNA
CTD
PMID:23196670
NCBI chr 1:20,960,772...21,009,874
Ensembl chr 1:20,960,830...21,009,874
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Parp1
poly (ADP-ribose) polymerase family, member 1
increases activity multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased activity of PARP1 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased cleavage of PARP1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PARP1 mRNA
CTD
PMID:16884709 PMID:20840854 PMID:23196670
NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
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Parp12
poly (ADP-ribose) polymerase family, member 12
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PARP12 mRNA
CTD
PMID:32119087
NCBI chr 6:39,063,346...39,095,283
Ensembl chr 6:39,063,344...39,095,283
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Pcdhb19
protocadherin beta 19
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCDHB12 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCDHB19 mRNA
CTD
PMID:23196670
NCBI chr18:37,630,049...37,637,181
Ensembl chr18:37,630,044...37,637,181
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Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
multiple interactions decreases expression increases expression affects expression
ISO EXP
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 mRNA]; AHR affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 mRNA]; AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCK1 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of PCK1 mRNA]; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of PCK1 mRNA; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PCK1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of PCK1 mRNA
CTD
PMID:26396156 PMID:27509375 PMID:28163111 PMID:28973532 PMID:29474705 PMID:30312631 PMID:34848246 PMID:37080397 More...
NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
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Pcp4l1
Purkinje cell protein 4-like 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PCP4L1 mRNA
CTD
PMID:20702594
NCBI chr 1:171,000,833...171,023,837
Ensembl chr 1:171,000,831...171,023,837
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Pcsk4
proprotein convertase subtilisin/kexin type 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PCSK4 mRNA
CTD
PMID:32119087
NCBI chr10:80,157,117...80,165,583
Ensembl chr10:80,157,117...80,165,332
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Pcsk5
proprotein convertase subtilisin/kexin type 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PCSK5 mRNA
CTD
PMID:19692669
NCBI chr19:17,409,678...17,815,076
Ensembl chr19:17,409,683...17,814,996
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Pcsk6
proprotein convertase subtilisin/kexin type 6
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PCSK6 mRNA
CTD
PMID:23146750
NCBI chr 7:65,511,884...65,700,134
Ensembl chr 7:65,511,482...65,700,134
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Pcx
pyruvate carboxylase
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PC mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PC mRNA]
CTD
PMID:20959002 PMID:27509375 PMID:29474705 PMID:34848246
NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780
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Pcyt1a
phosphate cytidylyltransferase 1, choline, alpha isoform
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PCYT1A mRNA
CTD
PMID:32119087
NCBI chr16:32,249,739...32,293,883
Ensembl chr16:32,249,739...32,293,888
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Pde3b
phosphodiesterase 3B, cGMP-inhibited
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PDE3B mRNA
CTD
PMID:23196670
NCBI chr 7:114,014,388...114,137,173
Ensembl chr 7:114,014,516...114,138,486
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Pde4b
phosphodiesterase 4B, cAMP specific
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDE4B mRNA
CTD
PMID:23196670
NCBI chr 4:101,944,529...102,464,459
Ensembl chr 4:101,944,740...102,464,456
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Pde5a
phosphodiesterase 5A, cGMP-specific
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDE5A mRNA
CTD
PMID:23196670
NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023
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Pde7b
phosphodiesterase 7B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDE7B mRNA
CTD
PMID:23196670
NCBI chr10:20,272,798...20,600,824
Ensembl chr10:20,273,750...20,600,824
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Pdgfa
platelet derived growth factor, alpha
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDGFA mRNA
CTD
PMID:23196670
NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125
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Pdia3
protein disulfide isomerase associated 3
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of PDIA3 protein
CTD
PMID:23457121
NCBI chr 2:121,244,383...121,269,168
Ensembl chr 2:121,244,256...121,269,168
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Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PDK1 mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PDK1 mRNA]
CTD
PMID:30821169
NCBI chr 2:71,703,398...71,734,202
Ensembl chr 2:71,703,568...71,734,202
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Pdk2
pyruvate dehydrogenase kinase, isoenzyme 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDK2 mRNA
CTD
PMID:23196670
NCBI chr11:94,917,084...94,932,197
Ensembl chr11:94,917,084...94,932,180
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Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDK4 mRNA
CTD
PMID:23196670
NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309
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Pdlim2
PDZ and LIM domain 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PDLIM2 mRNA
CTD
PMID:19692669
NCBI chr14:70,401,667...70,415,140
Ensembl chr14:70,401,667...70,415,130
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Pdp2
pyruvate dehydrogenase phosphatase catalytic subunit 2
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of PDP2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDP2 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 8:105,318,104...105,325,658
Ensembl chr 8:105,318,083...105,325,658
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Pdzd2
PDZ domain containing 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PDZD2 mRNA
CTD
PMID:23196670
NCBI chr15:12,359,797...12,740,052
Ensembl chr15:12,359,797...12,740,010
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Pdzrn3
PDZ domain containing RING finger 3
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PDZRN3 mRNA
CTD
PMID:20702594
NCBI chr 6:101,126,568...101,354,858
Ensembl chr 6:101,126,570...101,354,858
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Pecam1
platelet/endothelial cell adhesion molecule 1
multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of PECAM1 protein]
CTD
PMID:28973532
NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454
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Per3
period circadian clock 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PER3 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 4:151,081,475...151,129,167
Ensembl chr 4:151,088,109...151,129,122
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Pf4
platelet factor 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PF4 mRNA
CTD
PMID:34256052
NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242
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Pfkl
phosphofructokinase, liver, B-type
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PFKL mRNA
CTD
PMID:23196670
NCBI chr10:77,822,781...77,845,641
Ensembl chr10:77,822,781...77,845,917
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Pfn2
profilin 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PFN2 mRNA
CTD
PMID:23146750
NCBI chr 3:57,749,316...57,755,178
Ensembl chr 3:57,749,316...57,755,500
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Pgc
progastricsin (pepsinogen C)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PGC mRNA
CTD
PMID:23196670
NCBI chr17:48,037,767...48,045,403
Ensembl chr17:48,037,767...48,045,407
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Pgk1
phosphoglycerate kinase 1
increases expression affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PGK1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of PGK1 mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr X:105,230,706...105,247,305
Ensembl chr X:105,230,706...105,247,305
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Pgpep1
pyroglutamyl-peptidase I
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of PGPEP1 mRNA
CTD
PMID:30744511
NCBI chr 8:71,099,086...71,113,096
Ensembl chr 8:71,099,085...71,113,038
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Pgr
progesterone receptor
multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein]
CTD
PMID:26022396
NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
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Phb1
prohibitin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PHB1 mRNA
CTD
PMID:32119087
NCBI chr11:95,557,783...95,571,599
Ensembl chr11:95,557,783...95,571,599
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Phf1
PHD finger protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PHF1 mRNA
CTD
PMID:23196670
NCBI chr17:27,152,101...27,156,882
Ensembl chr17:27,152,026...27,156,882
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Phgdh
3-phosphoglycerate dehydrogenase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PHGDH mRNA
CTD
PMID:20959002
NCBI chr 3:98,220,487...98,247,285
Ensembl chr 3:98,220,486...98,247,306
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Phlda1
pleckstrin homology like domain, family A, member 1
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PHLDA1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PHLDA1 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr10:111,342,147...111,344,510
Ensembl chr10:111,342,147...111,344,506
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Phyh
phytanoyl-CoA hydroxylase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PHYH mRNA
CTD
PMID:23196670
NCBI chr 2:4,923,807...4,943,554
Ensembl chr 2:4,923,830...4,943,541
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Phyhd1
phytanoyl-CoA dioxygenase domain containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PHYHD1 mRNA
CTD
PMID:23196670
NCBI chr 2:30,156,215...30,172,161
Ensembl chr 2:30,156,215...30,172,161
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Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PHYHIPL mRNA
CTD
PMID:23196670
NCBI chr10:70,393,516...70,435,121
Ensembl chr10:70,393,512...70,491,795
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Pianp
PILR alpha associated neural protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PIANP mRNA
CTD
PMID:23196670
NCBI chr 6:124,973,683...124,980,059
Ensembl chr 6:124,973,657...124,980,059
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Pik3c2b
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PIK3C2B mRNA
CTD
PMID:32119087
NCBI chr 1:132,973,410...133,036,429
Ensembl chr 1:132,973,405...133,036,425
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Pik3c2g
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PIK3C2G mRNA
CTD
PMID:20959002
NCBI chr 6:139,591,070...139,915,010
Ensembl chr 6:139,564,219...139,915,010
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Pik3ip1
phosphoinositide-3-kinase interacting protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PIK3IP1 mRNA
CTD
PMID:23196670
NCBI chr11:3,280,731...3,292,971
Ensembl chr11:3,280,401...3,292,971
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Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PIK3R1 mRNA
CTD
PMID:23196670
NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
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Pik3r3
phosphoinositide-3-kinase regulatory subunit 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PIK3R3 mRNA
CTD
PMID:23196670
NCBI chr 4:116,078,593...116,160,253
Ensembl chr 4:116,078,815...116,160,253 Ensembl chr 4:116,078,815...116,160,253
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Pklr
pyruvate kinase liver and red blood cell
multiple interactions decreases expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PKLR mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PKLR mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKLR mRNA]
CTD
PMID:28973532 PMID:34256052
NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091
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Pkm
pyruvate kinase, muscle
multiple interactions increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of and affects the localization of and results in decreased activity of PKM protein; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM protein]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM protein]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM mRNA]; Fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM protein]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM protein
CTD
PMID:28284859 PMID:30821169
NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658
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Pla2g12a
phospholipase A2, group XIIA
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PLA2G12A mRNA
CTD
PMID:20702594
NCBI chr 3:129,672,255...129,689,474
Ensembl chr 3:129,672,255...129,689,474
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Pla2g2c
phospholipase A2, group IIC
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLA2G2C mRNA
CTD
PMID:23994337
NCBI chr 4:138,452,636...138,471,886
Ensembl chr 4:138,452,103...138,473,443
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Pla2g2d
phospholipase A2, group IID
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLA2G2D mRNA
CTD
PMID:23196670
NCBI chr 4:138,503,046...138,509,363
Ensembl chr 4:138,503,046...138,509,357
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Pla2g4a
phospholipase A2, group IVA (cytosolic, calcium-dependent)
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLA2G4A mRNA
CTD
PMID:23994337 PMID:35618242
NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041
G
Pla2g4c
phospholipase A2, group IVC (cytosolic, calcium-independent)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLA2G4C mRNA
CTD
PMID:32119087
NCBI chr 7:13,045,432...13,094,597
Ensembl chr 7:13,058,580...13,094,597
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Plaat1
phospholipase A and acyltransferase 1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of HRASLS mRNA
CTD
PMID:30744511
NCBI chr16:29,027,883...29,049,283
Ensembl chr16:29,028,447...29,049,283
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Plagl1
pleiomorphic adenoma gene-like 1
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLAGL1 mRNA
CTD
PMID:37080397
NCBI chr10:12,966,576...13,007,438
Ensembl chr10:12,936,248...13,007,438
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Plau
plasminogen activator, urokinase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLAU mRNA
CTD
PMID:35618242
NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
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Plb1
phospholipase B1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLB1 mRNA
CTD
PMID:23146750
NCBI chr 5:32,390,035...32,521,700
Ensembl chr 5:32,390,052...32,523,864
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Plcb1
phospholipase C, beta 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLCB1 mRNA
CTD
PMID:32119087
NCBI chr 2:134,628,084...135,317,178
Ensembl chr 2:134,627,987...135,317,178
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Plcb4
phospholipase C, beta 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLCB4 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 2:135,500,523...135,856,522
Ensembl chr 2:135,500,931...135,856,513
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Plce1
phospholipase C, epsilon 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLCE1 mRNA
CTD
PMID:23196670
NCBI chr19:38,469,438...38,773,549
Ensembl chr19:38,469,557...38,773,474
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Plcl1
phospholipase C-like 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLCL1 mRNA
CTD
PMID:23196670
NCBI chr 1:55,442,722...55,793,444
Ensembl chr 1:55,445,080...55,793,444
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Plekha5
pleckstrin homology domain containing, family A member 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLEKHA5 mRNA
CTD
PMID:23196670
NCBI chr 6:140,369,358...140,542,836
Ensembl chr 6:140,369,780...140,542,836
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Plekha6
pleckstrin homology domain containing, family A member 6
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLEKHA6 mRNA
CTD
PMID:32119087
NCBI chr 1:133,089,770...133,231,173
Ensembl chr 1:133,091,948...133,231,173
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Plekhf1
pleckstrin homology domain containing, family F (with FYVE domain) member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLEKHF1 mRNA
CTD
PMID:19692669
NCBI chr 7:37,920,078...37,927,418
Ensembl chr 7:37,916,396...37,927,440
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Plekho1
pleckstrin homology domain containing, family O member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLEKHO1 mRNA
CTD
PMID:23196670
NCBI chr 3:95,896,110...95,903,258
Ensembl chr 3:95,895,741...95,903,313
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Plg
plasminogen
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PLG mRNA
CTD
PMID:21703328
NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272
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Plin2
perilipin 2
multiple interactions affects expression
ISO EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of PLIN2 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of PLIN2 mRNA
CTD
PMID:16984957 PMID:37080397
NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
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Plk1
polo like kinase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PLK1 mRNA
CTD
PMID:23196670
NCBI chr 7:121,758,658...121,769,107
Ensembl chr 7:121,758,662...121,769,096
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Pllp
plasma membrane proteolipid
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLLP mRNA
CTD
PMID:32119087
NCBI chr 8:95,401,523...95,422,870
Ensembl chr 8:95,401,522...95,422,906
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Plpp3
phospholipid phosphatase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLPP3 mRNA
CTD
PMID:23196670 PMID:29947894
NCBI chr 4:105,014,544...105,089,964
Ensembl chr 4:105,014,544...105,089,961
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Plscr4
phospholipid scramblase 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PLSCR4 mRNA
CTD
PMID:23196670
NCBI chr 9:92,339,431...92,374,509
Ensembl chr 9:92,339,426...92,374,509
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Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased activity of PMAIP1 protein]
CTD
PMID:20840854
NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
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Pmm1
phosphomannomutase 1
affects expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PMM1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PMM1 mRNA
CTD
PMID:20702594 PMID:32119087
NCBI chr15:81,835,307...81,845,131
Ensembl chr15:81,835,309...81,845,131
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Pmp22
peripheral myelin protein 22
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PMP22 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PMP22 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr11:63,019,808...63,050,373
Ensembl chr11:63,019,808...63,050,373
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Pnpla3
patatin-like phospholipase domain containing 3
multiple interactions decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of PNPLA3 mRNA]; [aroclor 1260 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of PNPLA3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PNPLA3 mRNA
CTD
PMID:30312631
NCBI chr15:84,052,017...84,073,720
Ensembl chr15:84,052,038...84,071,437
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Pnpla7
patatin-like phospholipase domain containing 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PNPLA7 mRNA
CTD
PMID:23196670
NCBI chr 2:24,865,235...24,944,084
Ensembl chr 2:24,866,045...24,944,069
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Pnrc1
proline-rich nuclear receptor coactivator 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PNRC1 mRNA
CTD
PMID:20959002
NCBI chr 4:33,245,423...33,248,787
Ensembl chr 4:33,245,423...33,290,163
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Podxl
podocalyxin-like
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PODXL mRNA
CTD
PMID:23196670
NCBI chr 6:31,496,428...31,540,872
Ensembl chr 6:31,496,423...31,540,916
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Pola2
polymerase (DNA directed), alpha 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of POLA2 mRNA
CTD
PMID:23196670
NCBI chr19:5,990,574...6,014,266
Ensembl chr19:5,990,570...6,014,230
G
Pold1
polymerase (DNA directed), delta 1, catalytic subunit
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of POLD1 mRNA
CTD
PMID:23196670
NCBI chr 7:44,182,168...44,198,239
Ensembl chr 7:44,182,170...44,198,273
G
Polg
polymerase (DNA directed), gamma
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of POLG mRNA
CTD
PMID:23196670
NCBI chr 7:79,095,979...79,117,659
Ensembl chr 7:79,095,979...79,116,110
G
Polg2
polymerase (DNA directed), gamma 2, accessory subunit
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of POLG2 mRNA
CTD
PMID:20959002
NCBI chr11:106,659,030...106,670,363
Ensembl chr11:106,659,079...106,670,363
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Polm
polymerase (DNA directed), mu
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of POLM mRNA
CTD
PMID:32119087
NCBI chr11:5,777,860...5,788,831
Ensembl chr11:5,777,860...5,788,016
G
Pomc
pro-opiomelanocortin-alpha
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of POMC mRNA
CTD
PMID:32119087
NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
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Pon1
paraoxonase 1
decreases expression multiple interactions increases activity increases expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PON1 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of PON1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased activity of PON1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of and results in increased activity of PON1 protein; Acetylcysteine affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of PON1 protein]; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON1 mRNA]; Selenic Acid deficiency inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON1 mRNA]; Selenic Acid deficiency promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of PON1 protein]; Selenic Acid inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON1 mRNA] 3,3',4,4',5-pentachlorobiphenyl, PCB-126, increases expression of mRNA in rat liver
CTD RGD
PMID:19692669 PMID:22266287 PMID:22653878 PMID:23457121 PMID:23644946 PMID:25530946 PMID:26006071 PMID:34256052 PMID:23644946 More...
RGD:401794573
NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
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Pon2
paraoxonase 2
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PON2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON2 mRNA
CTD
PMID:22653878 PMID:23196670 PMID:26006071
NCBI chr 6:5,264,620...5,298,408
Ensembl chr 6:5,264,147...5,298,455
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Pon3
paraoxonase 3
decreases expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PON3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PON3 mRNA
CTD
PMID:22653878 PMID:25530946 PMID:26006071
NCBI chr 6:5,216,253...5,256,236
Ensembl chr 6:5,220,852...5,256,286
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Pot1a
protection of telomeres 1A
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of POT1 mRNA 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of POT1 mRNA]
CTD
PMID:26330309
NCBI chr 6:25,743,939...25,809,280
Ensembl chr 6:25,743,736...25,809,245
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Ppa1
pyrophosphatase (inorganic) 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PPA1 mRNA
CTD
PMID:32119087
NCBI chr10:61,484,400...61,509,944
Ensembl chr10:61,484,331...61,509,947
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Ppara
peroxisome proliferator activated receptor alpha
decreases expression multiple interactions increases expression affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPARA mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARA mRNA]; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of PPARA mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PPARA mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of PPARA mRNA
CTD
PMID:26396156 PMID:28163111 PMID:28973532 PMID:29474705 PMID:34848246 PMID:37080397 More...
NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
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Ppard
peroxisome proliferator activator receptor delta
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PPARD mRNA
CTD
PMID:37080397
NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
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Pparg
peroxisome proliferator activated receptor gamma
multiple interactions decreases expression
ISO EXP
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPARG mRNA] 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of PPARG mRNA]
CTD
PMID:25304490 PMID:28973532 PMID:35618242
NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
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Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
decreases expression affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPARGC1A mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of PPARGC1A mRNA
CTD
PMID:27509375 PMID:37080397
NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
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Ppargc1b
peroxisome proliferative activated receptor, gamma, coactivator 1 beta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPARGC1B mRNA
CTD
PMID:35618242
NCBI chr18:61,424,516...61,533,846
Ensembl chr18:61,431,207...61,533,502
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Ppef2
protein phosphatase, EF hand calcium-binding domain 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPEF2 mRNA
CTD
PMID:32119087
NCBI chr 5:92,374,109...92,404,759
Ensembl chr 5:92,374,538...92,404,137
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Ppl
periplakin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPL mRNA
CTD
PMID:19692669
NCBI chr16:4,904,155...4,950,345
Ensembl chr16:4,904,155...4,950,285
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Ppox
protoporphyrinogen oxidase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPOX mRNA
CTD
PMID:20959002
NCBI chr 1:171,104,564...171,108,955
Ensembl chr 1:171,103,563...171,108,760
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Ppp1r3b
protein phosphatase 1, regulatory subunit 3B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPP1R3B mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr 8:35,842,847...35,855,293
Ensembl chr 8:35,842,893...35,855,293
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Ppp1r3c
protein phosphatase 1, regulatory subunit 3C
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPP1R3C mRNA
CTD
PMID:23196670
NCBI chr19:36,709,131...36,714,004
Ensembl chr19:36,709,131...36,714,053
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Ppp2r2b
protein phosphatase 2, regulatory subunit B, beta
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of PPP2R2B mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPP2R2B mRNA
CTD
PMID:16984957 PMID:23196670
NCBI chr18:42,777,811...43,192,827
Ensembl chr18:42,770,497...43,216,192
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Ppp2r5e
protein phosphatase 2, regulatory subunit B', epsilon
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PPP2R5E mRNA
CTD
PMID:23994337
NCBI chr12:75,496,237...75,643,064
Ensembl chr12:75,497,655...75,643,019
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Ppy
pancreatic polypeptide
increases expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PPY mRNA 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [aroclor 1260 results in increased expression of PPY mRNA]; aroclor 1260 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PPY mRNA]
CTD
PMID:30312631
NCBI chr11:101,990,757...101,992,145
Ensembl chr11:101,990,756...101,992,145
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Prdm8
PR domain containing 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRDM8 mRNA
CTD
PMID:32119087
NCBI chr 5:98,315,241...98,335,313
Ensembl chr 5:98,315,057...98,336,850
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Prdx1
peroxiredoxin 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of PRDX1 mRNA
CTD
PMID:37080397
NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
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Prelp
proline arginine-rich end leucine-rich repeat
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PRELP mRNA
CTD
PMID:23196670
NCBI chr 1:133,838,042...133,857,820
Ensembl chr 1:133,838,042...133,849,152
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Prim1
DNA primase, p49 subunit
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRIM1 mRNA
CTD
PMID:23196670
NCBI chr10:127,851,084...127,865,899
Ensembl chr10:127,851,041...127,865,906
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Prkaa1
protein kinase, AMP-activated, alpha 1 catalytic subunit
multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased phosphorylation of and results in decreased activity of PRKAA1 protein
CTD
PMID:29474705
NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380
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Prkaa2
protein kinase, AMP-activated, alpha 2 catalytic subunit
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRKAA2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased phosphorylation of and results in decreased activity of PRKAA2 protein
CTD
PMID:23196670 PMID:29474705
NCBI chr 4:104,886,846...104,967,095
Ensembl chr 4:104,887,071...104,967,087
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Prkar2a
protein kinase, cAMP dependent regulatory, type II alpha
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRKAR2A mRNA
CTD
PMID:32119087
NCBI chr 9:108,569,342...108,627,643
Ensembl chr 9:108,566,513...108,627,635
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Prkcd
protein kinase C, delta
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRKCD mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased phosphorylation of PRKCD protein]
CTD
PMID:20959002 PMID:24709675
NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167
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Prlr
prolactin receptor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PRLR mRNA
CTD
PMID:20959002
NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266
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Prnp
prion protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PRNP mRNA
CTD
PMID:23196670
NCBI chr 2:131,751,848...131,780,356
Ensembl chr 2:131,751,848...131,780,349
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Prodh2
proline dehydrogenase (oxidase) 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PRODH2 mRNA
CTD
PMID:20959002
NCBI chr 7:30,193,011...30,212,830
Ensembl chr 7:30,193,047...30,212,827
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Prph
peripherin
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PRPH mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRPH mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr15:98,951,452...98,956,858
Ensembl chr15:98,953,055...98,956,859
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Prrx2
paired related homeobox 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PRRX2 mRNA
CTD
PMID:32119087
NCBI chr 2:30,735,076...30,771,263
Ensembl chr 2:30,724,984...30,771,263
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Prss12
serine protease 12 neurotrypsin (motopsin)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PRSS12 mRNA
CTD
PMID:23196670
NCBI chr 3:123,240,562...123,300,251
Ensembl chr 3:123,240,562...123,300,246
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Psat1
phosphoserine aminotransferase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PSAT1 mRNA
CTD
PMID:20959002
NCBI chr19:15,882,487...15,902,423
Ensembl chr19:15,882,042...15,924,701
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Psmb8
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PSMB8 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PSMB8 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr17:34,417,169...34,420,428
Ensembl chr17:34,416,695...34,420,428
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Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PSMB9 mRNA
CTD
PMID:23196670
NCBI chr17:34,401,006...34,406,347
Ensembl chr17:34,400,961...34,406,738
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Ptdss1
phosphatidylserine synthase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTDSS1 mRNA
CTD
PMID:23196670
NCBI chr13:67,080,894...67,146,465
Ensembl chr13:67,080,894...67,146,465
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Pter
phosphotriesterase related
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTER mRNA
CTD
PMID:23196670
NCBI chr 2:12,928,828...13,008,265
Ensembl chr 2:12,928,852...13,008,266
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Ptger4
prostaglandin E receptor 4 (subtype EP4)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGER4 mRNA
CTD
PMID:35618242
NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668
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Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions affects expression increases expression
ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA]; [Estradiol co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of PTGS2 mRNA; [Estradiol co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of PTGS2 protein; alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA]; Estradiol promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA]; fulvestrant promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA] 3,4,5,3',4'-pentachlorobiphenyl affects the expression of PTGS2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTGS2 protein
CTD
PMID:21513769 PMID:21703328 PMID:22262711 PMID:23196670 PMID:35618242
NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
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Pth
parathyroid hormone
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTH protein
CTD
PMID:31820026
NCBI chr 7:112,984,783...112,987,879
Ensembl chr 7:112,984,787...112,987,777
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Pthlh
parathyroid hormone-like peptide
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTHLH mRNA
CTD
PMID:35618242
NCBI chr 6:147,153,607...147,165,511
Ensembl chr 6:147,153,599...147,165,681
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Ptk2b
PTK2 protein tyrosine kinase 2 beta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTK2B mRNA
CTD
PMID:23196670
NCBI chr14:66,390,706...66,518,549
Ensembl chr14:66,390,706...66,518,501
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Ptms
parathymosin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTMS mRNA
CTD
PMID:20959002
NCBI chr 6:124,890,638...124,894,909
Ensembl chr 6:124,890,644...124,897,066
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Ptn
pleiotrophin
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTN mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr 6:36,691,863...36,787,114
Ensembl chr 6:36,691,864...36,787,155
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Ptpn1
protein tyrosine phosphatase, non-receptor type 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTPN1 mRNA
CTD
PMID:23196670
NCBI chr 2:167,772,670...167,821,305
Ensembl chr 2:167,773,977...167,821,305
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Ptpn14
protein tyrosine phosphatase, non-receptor type 14
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTPN14 mRNA
CTD
PMID:32119087
NCBI chr 1:189,460,417...189,608,892
Ensembl chr 1:189,460,465...189,608,892
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Ptpn21
protein tyrosine phosphatase, non-receptor type 21
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTPN21 mRNA
CTD
PMID:20959002
NCBI chr12:98,643,000...98,703,664
Ensembl chr12:98,643,000...98,703,664
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Ptpn9
protein tyrosine phosphatase, non-receptor type 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTPN9 mRNA
CTD
PMID:23196670
NCBI chr 9:56,902,252...56,970,092
Ensembl chr 9:56,902,207...56,970,091
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Ptprd
protein tyrosine phosphatase receptor type D
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTPRD mRNA
CTD
PMID:20959002
NCBI chr 4:75,859,474...78,132,282
Ensembl chr 4:75,859,475...78,130,198
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Ptprf
protein tyrosine phosphatase receptor type F
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTPRF mRNA
CTD
PMID:20959002
NCBI chr 4:118,065,410...118,148,602
Ensembl chr 4:118,065,410...118,148,602
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Ptprn
protein tyrosine phosphatase receptor type N
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PTPRN mRNA
CTD
PMID:20959002
NCBI chr 1:75,223,679...75,241,437
Ensembl chr 1:75,223,671...75,241,146
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Ptprz1
protein tyrosine phosphatase receptor type Z, polypeptide 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTPRZ1 mRNA
CTD
PMID:23196670
NCBI chr 6:22,875,302...23,052,915
Ensembl chr 6:22,875,501...23,052,915
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Pttg1
pituitary tumor-transforming gene 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PTTG1 mRNA
CTD
PMID:23196670
NCBI chr11:43,311,097...43,317,417
Ensembl chr11:43,311,077...43,317,078
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Pus1
pseudouridine synthase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PUS1 mRNA
CTD
PMID:19692669
NCBI chr 5:110,921,533...110,928,523
Ensembl chr 5:110,921,533...110,928,525
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Pvr
poliovirus receptor
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PVR mRNA
CTD
PMID:23196670
NCBI chr 7:19,637,503...19,655,068
Ensembl chr 7:19,637,503...19,655,085
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Pxk
PX domain containing serine/threonine kinase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PXK mRNA
CTD
PMID:23196670
NCBI chr14:14,304,656...14,371,593
Ensembl chr14:14,304,656...14,371,562
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Pygl
liver glycogen phosphorylase
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PYGL mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of PYGL mRNA]
CTD
PMID:27509375 PMID:29474705 PMID:34848246
NCBI chr12:70,237,589...70,274,457
Ensembl chr12:70,237,585...70,278,262
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Rab30
RAB30, member RAS oncogene family
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RAB30 mRNA
CTD
PMID:23196670
NCBI chr 7:92,390,845...92,493,743
Ensembl chr 7:92,390,811...92,493,743
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Rab3d
RAB3D, member RAS oncogene family
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RAB3D mRNA
CTD
PMID:23196670
NCBI chr 9:21,818,787...21,829,623
Ensembl chr 9:21,818,787...21,829,488
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Rab3il1
RAB3A interacting protein (rabin3)-like 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RAB3IL1 mRNA
CTD
PMID:23146750 PMID:23196670
NCBI chr19:9,979,033...10,015,744
Ensembl chr19:9,979,033...10,015,744
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Rab8b
RAB8B, member RAS oncogene family
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RAB8B mRNA
CTD
PMID:23196670
NCBI chr 9:66,750,891...66,826,987
Ensembl chr 9:66,750,946...66,826,969
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Rab9
RAB9, member RAS oncogene family
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RAB9 mRNA
CTD
PMID:23196670
NCBI chr X:165,240,247...165,262,863
Ensembl chr X:165,240,249...165,262,863
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Raf1
v-raf-leukemia viral oncogene 1
multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in decreased activity of RAF1 protein
CTD
PMID:20840854
NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596
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Ralb
v-ral simian leukemia viral oncogene B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RALB mRNA
CTD
PMID:20959002
NCBI chr 1:119,398,035...119,432,512
Ensembl chr 1:119,398,035...119,432,524
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Ralgds
ral guanine nucleotide dissociation stimulator
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RALGDS mRNA
CTD
PMID:23196670
NCBI chr 2:28,403,037...28,443,085
Ensembl chr 2:28,403,137...28,443,093
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Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RALGPS1 mRNA
CTD
PMID:32119087
NCBI chr 2:33,023,431...33,261,569
Ensembl chr 2:33,023,429...33,261,498
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Rangap1
RAN GTPase activating protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RANGAP1 mRNA
CTD
PMID:23196670
NCBI chr15:81,588,449...81,614,120
Ensembl chr15:81,588,449...81,629,731
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Rap2a
RAS related protein 2a
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RAP2A mRNA
CTD
PMID:23196670
NCBI chr14:120,715,873...120,744,606
Ensembl chr14:120,715,856...120,744,606
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Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RAPGEF2 mRNA
CTD
PMID:19692669
NCBI chr 3:78,969,818...79,194,681
Ensembl chr 3:78,969,823...79,193,824
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Rarres2
retinoic acid receptor responder (tazarotene induced) 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RARRES2 mRNA
CTD
PMID:32119087
NCBI chr 6:48,546,630...48,549,778
Ensembl chr 6:48,546,630...48,549,723
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Rasal1
RAS protein activator like 1 (GAP1 like)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RASAL1 mRNA
CTD
PMID:23146750
NCBI chr 5:120,786,105...120,817,662
Ensembl chr 5:120,786,877...120,817,662
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Rasl10b
RAS-like, family 10, member B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RASL10B mRNA
CTD
PMID:23146750
NCBI chr11:83,299,963...83,311,865
Ensembl chr11:83,299,963...83,311,865
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Rasl11a
RAS-like, family 11, member A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RASL11A mRNA
CTD
PMID:23196670
NCBI chr 5:146,781,881...146,784,536
Ensembl chr 5:146,781,881...146,784,537
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Rasl11b
RAS-like, family 11, member B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RASL11B mRNA
CTD
PMID:23196670
NCBI chr 5:74,355,987...74,360,138
Ensembl chr 5:74,355,947...74,360,142
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Rassf9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RASSF9 mRNA
CTD
PMID:23196670
NCBI chr10:102,348,083...102,385,598
Ensembl chr10:102,348,083...102,385,597
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Rbbp9
retinoblastoma binding protein 9, serine hydrolase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RBBP9 mRNA
CTD
PMID:23196670
NCBI chr 2:144,384,185...144,392,779
Ensembl chr 2:144,384,185...144,392,789
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Rbm33
RNA binding motif protein 33
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RBM33 mRNA
CTD
PMID:23994337
NCBI chr 5:28,521,817...28,624,242
Ensembl chr 5:28,522,119...28,624,237
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Rbms1
RNA binding motif, single stranded interacting protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RBMS1 mRNA
CTD
PMID:23196670
NCBI chr 2:60,580,537...60,794,224
Ensembl chr 2:60,580,537...60,793,536
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Rbp4
retinol binding protein 4, plasma
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RBP4 mRNA
CTD
PMID:23994337
NCBI chr19:38,105,068...38,113,769
Ensembl chr19:38,105,077...38,113,729
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Rbp7
retinol binding protein 7, cellular
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RBP7 mRNA
CTD
PMID:32119087
NCBI chr 4:149,534,144...149,550,919
Ensembl chr 4:149,534,144...149,539,435
G
Rcan1
regulator of calcineurin 1
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RCAN1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RCAN1 mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr16:92,188,839...92,263,057
Ensembl chr16:92,188,841...92,267,755
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Rcan2
regulator of calcineurin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RCAN2 mRNA
CTD
PMID:23196670
NCBI chr17:44,112,243...44,350,407
Ensembl chr17:44,112,242...44,350,407
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Rcn1
reticulocalbin 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of RCN1 mRNA
CTD
PMID:20702594
NCBI chr 2:105,216,293...105,229,664
Ensembl chr 2:105,216,636...105,229,664
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Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [ESR1 protein binds to RELA promoter]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [KDM4B protein binds to RELA promoter]; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of and affects the localization of RELA protein; KDM4B protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA protein Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA protein]
CTD
PMID:26519613 PMID:37080397 PMID:37598416
NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
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Repin1
replication initiator 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of REPIN1 mRNA
CTD
PMID:23196670
NCBI chr 6:48,570,817...48,576,016
Ensembl chr 6:48,570,817...48,576,016
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Resp18
regulated endocrine-specific protein 18
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RESP18 mRNA
CTD
PMID:20959002
NCBI chr 1:75,248,841...75,255,059
Ensembl chr 1:75,248,843...75,255,059
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Retn
resistin
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of RETN protein
CTD
PMID:28973532
NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110
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Retreg1
reticulophagy regulator 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RETREG1 mRNA
CTD
PMID:23196670
NCBI chr15:25,840,795...25,973,782
Ensembl chr15:25,843,266...25,973,773
G
Retsat
retinol saturase (all trans retinol 13,14 reductase)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RETSAT mRNA
CTD
PMID:23196670
NCBI chr 6:72,575,585...72,584,471
Ensembl chr 6:72,575,458...72,585,408
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Rfc2
replication factor C (activator 1) 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RFC2 mRNA
CTD
PMID:23196670
NCBI chr 5:134,611,544...134,627,182
Ensembl chr 5:134,610,220...134,630,659
G
Rfc3
replication factor C (activator 1) 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RFC3 mRNA
CTD
PMID:23196670
NCBI chr 5:151,566,282...151,574,673
Ensembl chr 5:151,566,221...151,574,707
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Rgs4
regulator of G-protein signaling 4
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of RGS4 mRNA
CTD
PMID:30744511
NCBI chr 1:169,569,046...169,575,211
Ensembl chr 1:169,569,046...169,575,211
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Rgs8
regulator of G-protein signaling 8
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RGS8 mRNA
CTD
PMID:19692669
NCBI chr 1:153,528,612...153,573,415
Ensembl chr 1:153,528,771...153,576,069
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Rgs9
regulator of G-protein signaling 9
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RGS9 mRNA
CTD
PMID:23994337
NCBI chr11:109,116,174...109,189,013
Ensembl chr11:109,116,181...109,188,955
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Rho
rhodopsin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RHO mRNA
CTD
PMID:23146750
NCBI chr 6:115,903,741...115,916,999
Ensembl chr 6:115,908,709...115,916,997
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Rhob
ras homolog family member B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RHOB mRNA
CTD
PMID:20959002
NCBI chr12:8,547,661...8,550,009
Ensembl chr12:8,547,661...8,550,009
G
Rhoj
ras homolog family member J
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RHOJ mRNA
CTD
PMID:32119087
NCBI chr12:75,355,087...75,448,229
Ensembl chr12:75,355,096...75,448,230
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Rhou
ras homolog family member U
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RHOU mRNA
CTD
PMID:32119087
NCBI chr 8:124,380,609...124,390,622
Ensembl chr 8:124,380,668...124,390,623
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Rhpn1
rhophilin, Rho GTPase binding protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RHPN1 mRNA
CTD
PMID:32119087
NCBI chr15:75,576,097...75,586,268
Ensembl chr15:75,576,129...75,587,334
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Rigi
RNA sensor RIG-I
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RIGI mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RIGI mRNA
CTD
PMID:32119087 PMID:35618242
NCBI chr 4:40,203,775...40,239,843
Ensembl chr 4:40,203,773...40,239,828
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Rnase4
ribonuclease, RNase A family 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RNASE4 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr14:51,328,534...51,343,608
Ensembl chr14:51,328,534...51,343,608
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Rnaset2b
ribonuclease T2B
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of RNASET2B mRNA
CTD
PMID:20702594
NCBI chr17:7,246,259...7,265,592
Ensembl chr17:7,238,033...7,278,698
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Rnf151
ring finger protein 151
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RNF151 mRNA
CTD
PMID:23146750
NCBI chr17:24,934,813...24,937,031
Ensembl chr17:24,934,813...24,937,037
G
Rnf207
ring finger protein 207
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RNF207 mRNA
CTD
PMID:23146750
NCBI chr 4:152,391,475...152,403,686
Ensembl chr 4:152,391,476...152,403,450
G
Rnpep
arginyl aminopeptidase (aminopeptidase B)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RNPEP mRNA
CTD
PMID:23196670
NCBI chr 1:135,190,447...135,211,765
Ensembl chr 1:135,190,450...135,211,822
G
Rpl5
ribosomal protein L5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RPL5 mRNA
CTD
PMID:19692669
NCBI chr 5:108,048,388...108,056,871
Ensembl chr 5:108,048,368...108,056,871
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Rplp0
ribosomal protein lateral stalk subunit P0
increases expression affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RPLP0 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of RPLP0 mRNA
CTD
PMID:23994337 PMID:37080397
NCBI chr 5:115,697,526...115,701,788
Ensembl chr 5:115,697,526...115,701,786
G
Rrad
Ras-related associated with diabetes
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RRAD mRNA
CTD
PMID:29947894
NCBI chr 8:105,354,702...105,357,921
Ensembl chr 8:105,354,702...105,357,959
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Rrm1
ribonucleotide reductase M1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RRM1 mRNA
CTD
PMID:23196670
NCBI chr 7:102,090,902...102,118,978
Ensembl chr 7:102,090,902...102,118,978
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Rrp1b
ribosomal RNA processing 1B
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RRP1B mRNA
CTD
PMID:23994337
NCBI chr17:32,255,087...32,281,839
Ensembl chr17:32,255,074...32,281,839
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Rsad2
radical S-adenosyl methionine domain containing 2
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RSAD2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RSAD2 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr12:26,492,742...26,506,451
Ensembl chr12:26,492,745...26,506,451
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Rtn1
reticulon 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RTN1 mRNA
CTD
PMID:23196670
NCBI chr12:72,258,523...72,455,828
Ensembl chr12:72,258,526...72,455,828
G
Rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of RUBCN mRNA
CTD
PMID:32119087
NCBI chr16:32,642,072...32,698,121
Ensembl chr16:32,642,073...32,698,136
G
Rufy3
RUN and FYVE domain containing 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RUFY3 mRNA
CTD
PMID:23196670
NCBI chr 5:88,711,305...88,799,276
Ensembl chr 5:88,712,899...88,799,251
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Runx1
runt related transcription factor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RUNX1 mRNA
CTD
PMID:23196670
NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
G
Ruvbl1
RuvB-like AAA ATPase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RUVBL1 mRNA
CTD
PMID:23196670
NCBI chr 6:88,442,391...88,474,548
Ensembl chr 6:88,442,391...88,474,554
G
Rxra
retinoid X receptor alpha
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of RXRA mRNA
CTD
PMID:37080397
NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
G
S100a1
S100 calcium binding protein A1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of S100A1 mRNA
CTD
PMID:23196670
NCBI chr 3:90,418,341...90,421,637
Ensembl chr 3:90,418,341...90,421,699
G
S100a10
S100 calcium binding protein A10 (calpactin)
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of S100A10 mRNA
CTD
PMID:19692669
NCBI chr 3:93,462,424...93,471,952
Ensembl chr 3:93,462,387...93,471,950
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Samd9l
sterile alpha motif domain containing 9-like
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SAMD9L mRNA
CTD
PMID:32119087
NCBI chr 6:3,372,257...3,399,458
Ensembl chr 6:3,372,257...3,399,572
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Sat1
spermidine/spermine N1-acetyl transferase 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SAT1 mRNA
CTD
PMID:21703328
NCBI chr X:153,996,128...153,999,345
Ensembl chr X:153,996,128...153,999,445
G
Sbpl
spermine binding protein-like
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ZG16B mRNA
CTD
PMID:23146750
NCBI chr17:24,172,059...24,174,247
Ensembl chr17:24,172,058...24,174,248
G
Sc5d
sterol-C5-desaturase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SC5D mRNA
CTD
PMID:23196670
NCBI chr 9:42,162,888...42,175,607
Ensembl chr 9:42,162,891...42,175,552
G
Scamp5
secretory carrier membrane protein 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SCAMP5 mRNA
CTD
PMID:23146750
NCBI chr 9:57,348,610...57,375,343
Ensembl chr 9:57,348,610...57,375,343
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Scara5
scavenger receptor class A, member 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SCARA5 mRNA
CTD
PMID:32119087
NCBI chr14:65,903,852...66,002,275
Ensembl chr14:65,903,852...66,002,275
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Scd1
stearoyl-Coenzyme A desaturase 1
decreases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SCD mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SCD1 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with aroclor 1260] results in decreased expression of SCD1 mRNA
CTD
PMID:23196670 PMID:29216392 PMID:30312631
NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
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Scd2
stearoyl-Coenzyme A desaturase 2
affects expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SCD2 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SCD2 mRNA
CTD
PMID:20702594 PMID:23196670
NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303
G
Scg5
secretogranin V
affects expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SCG5 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SCG5 mRNA
CTD
PMID:21703328 PMID:29947894
NCBI chr 2:113,606,708...113,659,423
Ensembl chr 2:113,606,707...113,659,466
G
Scgb3a2
secretoglobin, family 3A, member 2
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SCGB3A2 mRNA
CTD
PMID:20702594
NCBI chr18:43,897,346...43,900,464
Ensembl chr18:43,897,354...43,900,464
G
Scn4b
sodium channel, type IV, beta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SCN4B mRNA
CTD
PMID:23196670
NCBI chr 9:45,049,922...45,065,453
Ensembl chr 9:45,049,693...45,065,450
G
Scp2
sterol carrier protein 2, liver
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SCP2 mRNA
CTD
PMID:23196670
NCBI chr 4:107,901,027...108,002,168
Ensembl chr 4:107,901,036...108,002,195
G
Scpep1
serine carboxypeptidase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SCPEP1 mRNA
CTD
PMID:23196670
NCBI chr11:88,814,846...88,846,268
Ensembl chr11:88,814,846...88,846,291
G
Scube3
signal peptide, CUB domain, EGF-like 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SCUBE3 mRNA
CTD
PMID:32119087
NCBI chr17:28,361,074...28,393,825
Ensembl chr17:28,361,115...28,393,828
G
Sdc1
syndecan 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SDC1 mRNA
CTD
PMID:20959002
NCBI chr12:8,821,396...8,843,716
Ensembl chr12:8,821,323...8,843,715
G
Sdc2
syndecan 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SDC2 mRNA
CTD
PMID:23196670
NCBI chr15:32,920,869...33,034,867
Ensembl chr15:32,920,869...33,035,081
G
Sds
serine dehydratase
affects expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SDS mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SDS mRNA
CTD
PMID:21703328 PMID:27509375 PMID:29474705 PMID:34848246
NCBI chr 5:120,614,612...120,621,997
Ensembl chr 5:120,614,591...120,621,997
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Sele
selectin, endothelial cell
multiple interactions increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SELE protein] 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SELE protein
CTD
PMID:28973532
NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
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Selenop
selenoprotein P
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SELENOP mRNA
CTD
PMID:19692669 PMID:23146750 PMID:23196670
NCBI chr15:3,300,249...3,309,992
Ensembl chr15:3,298,029...3,309,990
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Selp
selectin, platelet
increases expression multiple interactions decreases secretion
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SELP protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SELP protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of SELP protein
CTD
PMID:28973532 PMID:29216392
NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
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Sema3g
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SEMA3G mRNA
CTD
PMID:32119087
NCBI chr14:30,939,830...30,952,309
Ensembl chr14:30,939,817...30,952,309
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Sema6a
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SEMA6A mRNA
CTD
PMID:23146750
NCBI chr18:47,378,321...47,504,267
Ensembl chr18:47,368,665...47,501,937
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Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SEMA6B mRNA
CTD
PMID:23146750
NCBI chr17:56,430,085...56,447,343
Ensembl chr17:56,430,085...56,447,343
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Septin4
septin 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SEPTIN4 mRNA
CTD
PMID:23196670
NCBI chr11:87,457,515...87,481,365
Ensembl chr11:87,457,479...87,481,365
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Serpina1a
serine (or cysteine) peptidase inhibitor, clade A, member 1A
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of SERPINA1A protein
CTD
PMID:23457121
NCBI chr12:103,819,554...103,829,878
Ensembl chr12:103,819,848...103,829,821
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Serpina7
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of SERPINA7 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SERPINA7 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr X:137,979,998...137,985,985
Ensembl chr X:137,980,006...137,985,985
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Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
multiple interactions increases expression
ISO
alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SERPINB2 mRNA]
CTD
PMID:22262711 PMID:23146750 PMID:29947894
NCBI chr 1:107,439,153...107,453,330
Ensembl chr 1:107,439,153...107,463,208
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Serpinb9
serine (or cysteine) peptidase inhibitor, clade B, member 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SERPINB9 mRNA
CTD
PMID:19692669
NCBI chr13:33,181,044...33,201,938
Ensembl chr13:33,187,233...33,201,940
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Serpine1
serine (or cysteine) peptidase inhibitor, clade E, member 1
increases expression affects expression multiple interactions increases secretion
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SERPINE1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of SERPINE1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SERPINE1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SERPINE1 protein 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 protein]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of SERPINE1 mRNA; [perfluorooctane sulfonic acid co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of SERPINE1 mRNA; [perfluorooctane sulfonic acid co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of SERPINE1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of SERPINE1 protein
CTD
PMID:19692669 PMID:21703328 PMID:28163111 PMID:28973532 PMID:29216392 PMID:33096110 More...
NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
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Sertad2
SERTA domain containing 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SERTAD2 mRNA
CTD
PMID:19692669
NCBI chr11:20,493,166...20,603,023
Ensembl chr11:20,493,253...20,603,021
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Sf3b4
splicing factor 3b, subunit 4
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SF3B4 mRNA
CTD
PMID:20702594
NCBI chr 3:96,079,822...96,084,880
Ensembl chr 3:96,079,648...96,084,880
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Sfmbt1
Scm-like with four mbt domains 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SFMBT1 mRNA
CTD
PMID:23196670
NCBI chr14:30,436,806...30,544,678
Ensembl chr14:30,436,806...30,544,678
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Sfn
stratifin
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of SFN protein
CTD
PMID:23457121
NCBI chr 4:133,327,867...133,329,163
Ensembl chr 4:133,327,867...133,329,479
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Sfr1
SWI5 dependent recombination repair 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SFR1 mRNA
CTD
PMID:23994337
NCBI chr19:47,720,159...47,724,027
Ensembl chr19:47,720,121...47,724,027
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Sfxn1
sideroflexin 1
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SFXN1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SFXN1 mRNA
CTD
PMID:20959002 PMID:23196670
NCBI chr13:54,225,675...54,262,365
Ensembl chr13:54,225,888...54,262,361
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Sgk2
serum/glucocorticoid regulated kinase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SGK2 mRNA
CTD
PMID:20959002
NCBI chr 2:162,829,249...162,856,059
Ensembl chr 2:162,829,250...162,856,047
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Sh3bp5
SH3-domain binding protein 5 (BTK-associated)
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SH3BP5 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SH3BP5 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr14:31,094,571...31,158,056
Ensembl chr14:31,081,837...31,158,035
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Sh3rf1
SH3 domain containing ring finger 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SH3RF1 mRNA
CTD
PMID:23196670
NCBI chr 8:61,677,117...61,918,327
Ensembl chr 8:61,676,906...61,849,105
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Shc2
SHC (Src homology 2 domain containing) transforming protein 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SHC2 mRNA
CTD
PMID:32119087
NCBI chr10:79,453,768...79,473,752
Ensembl chr10:79,453,885...79,473,752
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Shisa8
shisa family member 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SHISA8 mRNA
CTD
PMID:32119087
NCBI chr15:82,091,153...82,097,004
Ensembl chr15:82,090,369...82,097,016
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Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SHMT2 mRNA
CTD
PMID:23196670
NCBI chr10:127,352,992...127,358,313
Ensembl chr10:127,352,992...127,358,313
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Shroom2
shroom family member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SHROOM2 mRNA
CTD
PMID:23196670
NCBI chr X:151,392,505...151,553,784
Ensembl chr X:151,392,505...151,552,461
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Shroom4
shroom family member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SHROOM4 mRNA
CTD
PMID:32119087
NCBI chr X:6,312,012...6,549,508
Ensembl chr X:6,311,908...6,549,502
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Sigmar1
sigma non-opioid intracellular receptor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SIGMAR1 mRNA
CTD
PMID:23196670
NCBI chr 4:41,738,493...41,741,359
Ensembl chr 4:41,738,493...41,756,157
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Sipa1l2
signal-induced proliferation-associated 1 like 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SIPA1L2 mRNA
CTD
PMID:23196670
NCBI chr 8:126,144,807...126,296,602
Ensembl chr 8:126,144,802...126,296,547
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Sirpd
signal regulatory protein delta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SIRPD mRNA
CTD
PMID:23146750
NCBI chr 3:15,360,163...15,397,362
Ensembl chr 3:15,361,611...15,397,362
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Sirt1
sirtuin 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SIRT1 mRNA
CTD
PMID:37080397
NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
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Six5
sine oculis-related homeobox 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SIX5 mRNA
CTD
PMID:23146750
NCBI chr 7:18,828,469...18,832,474
Ensembl chr 7:18,828,519...18,832,474
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Slc13a3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of SLC13A3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC13A3 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 2:165,247,215...165,315,117
Ensembl chr 2:165,246,948...165,315,150
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Slc14a1
solute carrier family 14 (urea transporter), member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC14A1 mRNA
CTD
PMID:23196670
NCBI chr18:78,143,306...78,185,334
Ensembl chr18:78,143,306...78,185,334
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Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC16A1 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778
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Slc16a13
solute carrier family 16 (monocarboxylic acid transporters), member 13
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC16A13 mRNA
CTD
PMID:23196670
NCBI chr11:70,107,615...70,113,638
Ensembl chr11:70,107,615...70,111,890
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Slc16a2
solute carrier family 16 (monocarboxylic acid transporters), member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC16A2 mRNA
CTD
PMID:23196670
NCBI chr X:102,741,020...102,865,594
Ensembl chr X:102,741,020...102,865,589
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Slc17a1
solute carrier family 17 (sodium phosphate), member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC17A1 mRNA
CTD
PMID:19692669
NCBI chr13:24,051,607...24,079,713
Ensembl chr13:24,051,733...24,079,713
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Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC1A3 mRNA
CTD
PMID:23196670
NCBI chr15:8,663,608...8,742,648
Ensembl chr15:8,663,608...8,740,248
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Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC1A4 mRNA
CTD
PMID:23196670
NCBI chr11:20,252,180...20,282,713
Ensembl chr11:20,252,180...20,282,713
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Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC1A5 mRNA
CTD
PMID:23196670
NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199
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Slc20a1
solute carrier family 20, member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC20A1 mRNA
CTD
PMID:23196670
NCBI chr 2:129,038,662...129,053,535
Ensembl chr 2:129,040,684...129,053,536
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Slc22a7
solute carrier family 22 (organic anion transporter), member 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC22A7 mRNA
CTD
PMID:20959002
NCBI chr17:46,743,111...46,749,403
Ensembl chr17:46,743,109...46,749,383
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Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC25A10 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC25A10 mRNA
CTD
PMID:19692669 PMID:20959002
NCBI chr11:120,382,663...120,391,987
Ensembl chr11:120,382,666...120,390,013
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Slc25a15
solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC25A15 mRNA
CTD
PMID:32119087
NCBI chr 8:22,865,566...22,888,637
Ensembl chr 8:22,865,567...22,888,613
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Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC25A25 mRNA
CTD
PMID:23196670
NCBI chr 2:32,304,499...32,341,482
Ensembl chr 2:32,304,499...32,341,457
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Slc25a36
solute carrier family 25, member 36
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC25A36 mRNA
CTD
PMID:32119087
NCBI chr 9:96,957,014...96,993,094
Ensembl chr 9:96,957,014...96,993,210
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Slc26a2
solute carrier family 26 (sulfate transporter), member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC26A2 mRNA
CTD
PMID:23196670
NCBI chr18:61,329,926...61,344,668
Ensembl chr18:61,325,991...61,344,684
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Slc27a1
solute carrier family 27 (fatty acid transporter), member 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SLC27A1 mRNA
CTD
PMID:37080397
NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946
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Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC27A2 mRNA
CTD
PMID:23994337
NCBI chr 2:126,394,944...126,430,163
Ensembl chr 2:126,394,327...126,430,163
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Slc27a3
solute carrier family 27 (fatty acid transporter), member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC27A3 mRNA
CTD
PMID:19692669
NCBI chr 3:90,292,540...90,298,693
Ensembl chr 3:90,292,546...90,297,245
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Slc27a4
solute carrier family 27 (fatty acid transporter), member 4
affects expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SLC27A4 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC27A4 mRNA
CTD
PMID:21703328 PMID:37080397
NCBI chr 2:29,692,646...29,707,534
Ensembl chr 2:29,692,646...29,707,534
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Slc28a2
solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC28A2 mRNA
CTD
PMID:23196670
NCBI chr 2:122,256,836...122,291,633
Ensembl chr 2:122,256,958...122,291,618
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Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC29A1 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr17:45,896,126...45,910,544
Ensembl chr17:45,896,126...45,910,532
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Slc2a1
solute carrier family 2 (facilitated glucose transporter), member 1
increases expression multiple interactions decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC2A1 mRNA
CTD
PMID:30821169 PMID:35618242 PMID:37080397
NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180
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Slc2a2
solute carrier family 2 (facilitated glucose transporter), member 2
decreases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC2A2 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SLC2A2 mRNA AHR protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC2A2 mRNA]
CTD
PMID:26396156 PMID:28973532 PMID:29474705 PMID:34848246 PMID:37080397
NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
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Slc2a3
solute carrier family 2 (facilitated glucose transporter), member 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC2A3 mRNA
CTD
PMID:23196670
NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599
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Slc2a5
solute carrier family 2 (facilitated glucose transporter), member 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC2A5 mRNA
CTD
PMID:20959002
NCBI chr 4:150,203,801...150,228,625
Ensembl chr 4:150,203,740...150,228,626
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Slc35c2
solute carrier family 35, member C2
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased expression of SLC35C2 mRNA
CTD
PMID:30744511
NCBI chr 2:165,118,442...165,129,808
Ensembl chr 2:165,118,474...165,129,789
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Slc37a4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC37A4 mRNA
CTD
PMID:19692669
NCBI chr 9:44,308,243...44,314,263
Ensembl chr 9:44,308,149...44,314,265
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Slc38a2
solute carrier family 38, member 2
increases expression affects expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC38A2 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the expression of SLC38A2 mRNA
CTD
PMID:23196670 PMID:37080397
NCBI chr15:96,585,267...96,597,609
Ensembl chr15:96,585,273...96,597,611
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Slc39a3
solute carrier family 39 (zinc transporter), member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC39A3 mRNA
CTD
PMID:23196670
NCBI chr10:80,864,374...80,873,169
Ensembl chr10:80,864,372...80,873,260
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Slc39a8
solute carrier family 39 (metal ion transporter), member 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC39A8 mRNA
CTD
PMID:23146750
NCBI chr 3:135,522,644...135,594,333
Ensembl chr 3:135,531,040...135,594,333
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Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC3A2 mRNA
CTD
PMID:20959002
NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733
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Slc40a1
solute carrier family 40 (iron-regulated transporter), member 1
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC40A1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC40A1 protein
CTD
PMID:23196670 PMID:25686467
NCBI chr 1:45,947,230...45,965,690
Ensembl chr 1:45,947,228...45,965,683
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Slc41a2
solute carrier family 41, member 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC41A2 mRNA
CTD
PMID:19692669
NCBI chr10:83,066,712...83,174,657
Ensembl chr10:83,066,712...83,173,746
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Slc4a1
solute carrier family 4 (anion exchanger), member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC4A1 mRNA
CTD
PMID:20959002
NCBI chr11:102,239,646...102,256,107
Ensembl chr11:102,239,650...102,257,029
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Slc5a3
solute carrier family 5 (inositol transporters), member 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC5A3 mRNA
CTD
PMID:23196670
NCBI chr16:91,855,210...91,884,361
Ensembl chr16:91,855,210...91,884,361
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Slc66a2
solute carrier family 66 member 2
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC66A2 mRNA
CTD
PMID:23994337
NCBI chr18:80,298,458...80,335,940
Ensembl chr18:80,296,507...80,335,940
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Slc6a13
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC6A13 mRNA
CTD
PMID:20959002
NCBI chr 6:121,277,247...121,314,680
Ensembl chr 6:121,277,186...121,314,692
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Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of SLC6A6 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC6A6 mRNA
CTD
PMID:16984957 PMID:20959002 PMID:23196670
NCBI chr 6:91,661,031...91,736,044
Ensembl chr 6:91,661,034...91,736,047
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Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC7A1 mRNA
CTD
PMID:23196670
NCBI chr 5:148,264,220...148,336,714
Ensembl chr 5:148,264,220...148,336,714
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Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC7A11 mRNA
CTD
PMID:19692669 PMID:23146750
NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
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Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC7A5 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433
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Slc7a7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC7A7 mRNA
CTD
PMID:23196670
NCBI chr14:54,606,899...54,657,525
Ensembl chr14:54,606,899...54,655,237
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Slc7a8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC7A8 mRNA
CTD
PMID:23196670
NCBI chr14:54,959,672...55,019,343
Ensembl chr14:54,959,666...55,019,403
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Slc7a9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC7A9 mRNA
CTD
PMID:23196670
NCBI chr 7:35,148,152...35,165,459
Ensembl chr 7:35,148,221...35,165,461
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Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLC9A7 mRNA
CTD
PMID:32119087
NCBI chr X:19,965,090...20,158,274
Ensembl chr X:19,971,993...20,158,046
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Slco1a4
solute carrier organic anion transporter family, member 1a4
multiple interactions decreases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of SLCO1A4 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLCO1A4 mRNA
CTD
PMID:16984957 PMID:20959002
NCBI chr 6:141,751,164...141,802,011
Ensembl chr 6:141,751,166...141,801,925
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Slco2a1
solute carrier organic anion transporter family, member 2a1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLCO2A1 mRNA
CTD
PMID:20959002
NCBI chr 9:102,885,686...102,973,201
Ensembl chr 9:102,865,911...102,973,201
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Slco2b1
solute carrier organic anion transporter family, member 2b1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLCO2B1 mRNA
CTD
PMID:15919853
NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547
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Slco3a1
solute carrier organic anion transporter family, member 3a1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLCO3A1 mRNA
CTD
PMID:15919853
NCBI chr 7:73,925,166...74,204,528
Ensembl chr 7:73,925,167...74,204,528
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Slfn5
schlafen 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLFN5 mRNA
CTD
PMID:32119087
NCBI chr11:82,842,175...82,855,681
Ensembl chr11:82,842,175...82,855,666
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Slitrk5
SLIT and NTRK-like family, member 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SLITRK5 mRNA
CTD
PMID:32119087
NCBI chr14:111,912,547...111,920,576
Ensembl chr14:111,912,529...111,920,573
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Smad7
SMAD family member 7
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SMAD7 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SMAD7 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006
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Smad9
SMAD family member 9
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SMAD9 mRNA
CTD
PMID:23196670
NCBI chr 3:54,662,873...54,709,162
Ensembl chr 3:54,663,003...54,708,678
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Smarcb1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SMARCB1 mRNA
CTD
PMID:21703328
NCBI chr10:75,732,603...75,757,448
Ensembl chr10:75,732,603...75,757,451
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Smim3
small integral membrane protein 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SMIM3 mRNA
CTD
PMID:23196670
NCBI chr18:60,607,263...60,635,055
Ensembl chr18:60,607,263...60,635,059
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Smpd1
sphingomyelin phosphodiesterase 1, acid lysosomal
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SMPD1 mRNA
CTD
PMID:32119087
NCBI chr 7:105,203,567...105,207,596
Ensembl chr 7:105,203,567...105,207,596
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Smpd3
sphingomyelin phosphodiesterase 3, neutral
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SMPD3 mRNA
CTD
PMID:23196670
NCBI chr 8:106,979,180...107,064,597
Ensembl chr 8:106,979,180...107,064,620
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Snai1
snail family zinc finger 1
decreases expression increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SNAI1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]; fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]
CTD
PMID:23196670 PMID:28284859
NCBI chr 2:167,380,115...167,384,734
Ensembl chr 2:167,380,115...167,384,734
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Snap23
synaptosomal-associated protein 23
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAP23 mRNA
CTD
PMID:32119087
NCBI chr 2:120,398,137...120,436,829
Ensembl chr 2:120,398,152...120,431,736
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Sncg
synuclein, gamma
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SNCG mRNA
CTD
PMID:32119087
NCBI chr14:34,092,231...34,096,626
Ensembl chr14:34,092,231...34,096,746
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Snrk
SNF related kinase
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SNRK mRNA
CTD
PMID:23994337
NCBI chr 9:121,946,332...121,998,768
Ensembl chr 9:121,946,332...121,998,768
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Snx24
sorting nexing 24
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SNX24 mRNA
CTD
PMID:23196670
NCBI chr18:53,376,877...53,523,994
Ensembl chr18:53,378,734...53,523,992
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Socs2
suppressor of cytokine signaling 2
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SOCS2 mRNA
CTD
PMID:15371557 PMID:19692669
NCBI chr10:95,219,765...95,253,176
Ensembl chr10:95,221,224...95,253,042
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Sod1
superoxide dismutase 1, soluble
increases activity decreases expression multiple interactions decreases activity increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased activity of SOD1 protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SOD1 mRNA Sunphenon inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SOD1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of SOD1 protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SOD1 mRNA
CTD
PMID:24378064 PMID:25433332 PMID:26967026 PMID:37080397
NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
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Sod2
superoxide dismutase 2, mitochondrial
increases expression decreases activity
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SOD2 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SOD2 protein 3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of SOD2 protein
CTD
PMID:26660635 PMID:26967026
NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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Sod3
superoxide dismutase 3, extracellular
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SOD3 mRNA
CTD
PMID:37080397
NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760
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Sos1
SOS Ras/Rac guanine nucleotide exchange factor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SOS1 mRNA
CTD
PMID:19692669
NCBI chr17:80,701,181...80,787,882
Ensembl chr17:80,701,180...80,787,882
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Sparc
secreted acidic cysteine rich glycoprotein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SPARC mRNA
CTD
PMID:20959002
NCBI chr11:55,284,985...55,310,906
Ensembl chr11:55,285,326...55,314,009
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Sparcl1
SPARC-like 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SPARCL1 mRNA
CTD
PMID:20959002
NCBI chr 5:104,226,974...104,261,954
Ensembl chr 5:104,226,977...104,261,599
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Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SPC25 mRNA
CTD
PMID:23196670
NCBI chr 2:69,009,753...69,036,583
Ensembl chr 2:69,024,239...69,036,538
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Spink8
serine peptidase inhibitor, Kazal type 8
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SPINK8 mRNA
CTD
PMID:32119087
NCBI chr 9:109,641,271...109,655,696
Ensembl chr 9:109,641,348...109,655,701
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Spon1
spondin 1, (f-spondin) extracellular matrix protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SPON1 mRNA
CTD
PMID:23196670
NCBI chr 7:113,365,235...113,642,610
Ensembl chr 7:113,365,235...113,642,605
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Spp1
secreted phosphoprotein 1
affects expression increases expression decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SPP1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SPP1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SPP1 mRNA
CTD
PMID:20959002 PMID:21703328 PMID:23146750 PMID:37080397
NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
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Spp2
secreted phosphoprotein 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SPP2 mRNA
CTD
PMID:19692669
NCBI chr 1:88,334,688...88,356,022
Ensembl chr 1:88,334,683...88,354,160
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Sptbn1
spectrin beta, non-erythrocytic 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SPTBN1 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr11:30,049,395...30,218,384
Ensembl chr11:30,049,395...30,218,175
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Sqle
squalene epoxidase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SQLE mRNA
CTD
PMID:23196670
NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041
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Srd5a1
steroid 5 alpha-reductase 1
multiple interactions decreases expression increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] affects the expression of SRD5A1 protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of SRD5A1 mRNA; AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SRD5A1 mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SRD5A1 mRNA
CTD
PMID:16984957 PMID:19464308 PMID:20959002 PMID:34256052
NCBI chr13:69,721,568...69,759,611
Ensembl chr13:69,721,568...69,759,561
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Srd5a2
steroid 5 alpha-reductase 2
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] affects the expression of SRD5A2 protein
CTD
PMID:19464308
NCBI chr17:74,321,886...74,354,855
Ensembl chr17:74,323,950...74,354,911
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Srebf1
sterol regulatory element binding transcription factor 1
decreases expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SREBF1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SREBF1 protein
CTD
PMID:23994337 PMID:26693162
NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
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Srgn
serglycin
affects expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of SRGN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SRGN mRNA
CTD
PMID:20702594 PMID:23196670
NCBI chr10:62,329,612...62,363,224
Ensembl chr10:62,329,612...62,363,230
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Srm
spermidine synthase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SRM mRNA
CTD
PMID:23196670
NCBI chr 4:148,675,970...148,679,076
Ensembl chr 4:148,675,960...148,679,450
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Srp19
signal recognition particle 19
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SRP19 mRNA
CTD
PMID:23994337
NCBI chr18:34,464,185...34,469,652
Ensembl chr18:34,463,900...34,469,652
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Srpra
signal recognition particle receptor alpha
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SRPRA mRNA
CTD
PMID:23994337
NCBI chr 9:35,122,499...35,128,299
Ensembl chr 9:35,111,471...35,159,269
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Srpx
sushi-repeat-containing protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SRPX mRNA
CTD
PMID:23196670
NCBI chr X:9,904,216...9,983,879
Ensembl chr X:9,904,216...9,983,948
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Sst
somatostatin
multiple interactions
ISO
[2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of SST mRNA
CTD
PMID:19327374
NCBI chr16:23,708,327...23,710,041
Ensembl chr16:23,708,323...23,709,708
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Ssu2
ssu-2 homolog
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SSUH2 mRNA
CTD
PMID:32119087
NCBI chr 6:112,336,283...112,365,160
Ensembl chr 6:112,336,285...112,364,984
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St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ST3GAL1 mRNA
CTD
PMID:23196670
NCBI chr15:66,974,724...67,048,575
Ensembl chr15:66,974,724...67,048,679
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St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ST6GAL1 mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr16:23,043,478...23,179,100
Ensembl chr16:23,043,490...23,179,100
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St6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ST6GALNAC3 mRNA
CTD
PMID:23196670
NCBI chr 3:152,903,911...153,430,804
Ensembl chr 3:152,903,903...153,430,811
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Stab1
stabilin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAB1 mRNA
CTD
PMID:32119087
NCBI chr14:30,860,974...30,890,616
Ensembl chr14:30,860,970...30,890,598
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Star
steroidogenic acute regulatory protein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAR mRNA
CTD
PMID:20574914
NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
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Stat1
signal transducer and activator of transcription 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT1 mRNA
CTD
PMID:22262711
NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024
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Stat3
signal transducer and activator of transcription 3
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; WP1066 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]
CTD
PMID:28284859
NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
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Stc1
stanniocalcin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of STC1 mRNA
CTD
PMID:23196670
NCBI chr14:69,266,738...69,278,850
Ensembl chr14:69,266,687...69,279,253
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Stc2
stanniocalcin 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STC2 mRNA
CTD
PMID:23196670 PMID:29947894
NCBI chr11:31,309,441...31,320,061
Ensembl chr11:31,307,307...31,320,074
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Ston1
stonin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of STON1 mRNA
CTD
PMID:23196670
NCBI chr17:88,905,043...88,955,293
Ensembl chr17:88,905,112...88,970,014
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Stox2
storkhead box 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of STOX2 mRNA
CTD
PMID:23196670
NCBI chr 8:47,633,083...47,866,943
Ensembl chr 8:47,633,083...47,899,397
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Stxbp3
syntaxin binding protein 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of STXBP3 mRNA
CTD
PMID:23196670
NCBI chr 3:108,700,496...108,747,818
Ensembl chr 3:108,700,492...108,747,842
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Sugct
succinyl-CoA glutarate-CoA transferase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SUGCT mRNA
CTD
PMID:23196670
NCBI chr13:17,032,057...17,869,380
Ensembl chr13:17,032,057...17,870,138
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Sugt1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SUGT1 mRNA
CTD
PMID:32119087
NCBI chr14:79,825,100...79,868,237
Ensembl chr14:79,825,131...79,872,636
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Sulf1
sulfatase 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SULF1 mRNA
CTD
PMID:23196670
NCBI chr 1:12,762,421...12,946,090
Ensembl chr 1:12,762,501...12,931,416
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Sult1b1
sulfotransferase family 1B, member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SULT1B1 mRNA
CTD
PMID:19692669
NCBI chr 5:87,661,186...87,686,054
Ensembl chr 5:87,661,198...87,686,054
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Sult1c1
sulfotransferase family, cytosolic, 1C, member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SULT1C1 mRNA
CTD
PMID:20959002
NCBI chr17:54,268,643...54,297,659
Ensembl chr17:54,268,643...54,297,702
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Sult1e1
sulfotransferase family 1E, member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SULT1E1 mRNA
CTD
PMID:25433332
NCBI chr 5:87,723,827...87,739,470
Ensembl chr 5:87,723,828...87,739,453
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Susd4
sushi domain containing 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SUSD4 mRNA
CTD
PMID:32119087
NCBI chr 1:182,591,609...182,724,161
Ensembl chr 1:182,591,425...182,724,156
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Sycn
syncollin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SYCN mRNA
CTD
PMID:20959002
NCBI chr 7:28,240,310...28,241,635
Ensembl chr 7:28,240,310...28,241,634
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Sympk
symplekin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SYMPK mRNA
CTD
PMID:23146750
NCBI chr 7:18,758,321...18,788,542
Ensembl chr 7:18,758,302...18,788,543
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Synj2
synaptojanin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SYNJ2 mRNA
CTD
PMID:20959002
NCBI chr17:5,991,555...6,106,041
Ensembl chr17:5,991,555...6,094,565
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Synpo
synaptopodin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SYNPO mRNA
CTD
PMID:23196670
NCBI chr18:60,727,053...60,793,241
Ensembl chr18:60,727,045...60,793,214
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Syt12
synaptotagmin XII
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SYT12 mRNA
CTD
PMID:23196670
NCBI chr19:4,495,936...4,527,171
Ensembl chr19:4,495,936...4,527,475
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Syt15
synaptotagmin XV
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SYT15 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SYT15 mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr14:33,941,915...33,952,378
Ensembl chr14:33,941,552...33,952,377
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Sytl5
synaptotagmin-like 5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SYTL5 mRNA
CTD
PMID:32119087
NCBI chr X:9,613,851...9,871,268
Ensembl chr X:9,751,861...9,860,782
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Tacc1
transforming, acidic coiled-coil containing protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TACC1 mRNA
CTD
PMID:23196670
NCBI chr 8:25,644,568...25,730,901
Ensembl chr 8:25,644,568...25,746,604
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Tacc3
transforming, acidic coiled-coil containing protein 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TACC3 mRNA
CTD
PMID:23196670
NCBI chr 5:33,814,808...33,836,331
Ensembl chr 5:33,815,472...33,836,339
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Tacr1
tachykinin receptor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TACR1 mRNA
CTD
PMID:32119087
NCBI chr 6:82,378,990...82,537,085
Ensembl chr 6:82,379,315...82,537,085
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Tagln
transgelin
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TAGLN mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TAGLN mRNA
CTD
PMID:19692669 PMID:23196670
NCBI chr 9:45,840,926...45,847,356
Ensembl chr 9:45,840,917...45,847,356
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Tamalin
trafficking regulator and scaffold protein tamalin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TAMALIN mRNA
CTD
PMID:32119087
NCBI chr15:101,122,088...101,130,637
Ensembl chr15:101,122,069...101,130,637
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Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TAP1 mRNA
CTD
PMID:23196670
NCBI chr17:34,406,530...34,416,199
Ensembl chr17:34,406,527...34,416,199
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Tapbp
TAP binding protein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TAPBP mRNA
CTD
PMID:23196670
NCBI chr17:34,138,452...34,148,264
Ensembl chr17:34,134,873...34,148,266
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Tat
tyrosine aminotransferase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TAT mRNA
CTD
PMID:19692669
NCBI chr 8:110,712,710...110,726,436
Ensembl chr 8:110,717,069...110,726,435
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Tax1bp1
Tax1 (human T cell leukemia virus type I) binding protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TAX1BP1 mRNA
CTD
PMID:23196670
NCBI chr 6:52,690,677...52,743,765
Ensembl chr 6:52,690,714...52,743,765
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Tbc1d1
TBC1 domain family, member 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TBC1D1 mRNA
CTD
PMID:32119087
NCBI chr 5:64,313,648...64,508,829
Ensembl chr 5:64,313,648...64,508,829
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Tbcel
tubulin folding cofactor E-like
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TBCEL mRNA
CTD
PMID:23994337
NCBI chr 9:42,323,612...42,383,534
Ensembl chr 9:42,323,612...42,419,105
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Tbx3
T-box 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TBX3 mRNA
CTD
PMID:19692669
NCBI chr 5:119,808,600...119,822,789
Ensembl chr 5:119,808,734...119,822,789
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Tc2n
tandem C2 domains, nuclear
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TC2N mRNA
CTD
PMID:32119087
NCBI chr12:101,611,705...101,685,178
Ensembl chr12:101,611,702...101,684,782
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Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TCF7L2 mRNA
CTD
PMID:37080397
NCBI chr19:55,730,227...55,922,091
Ensembl chr19:55,730,252...55,922,086
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Tcn2
transcobalamin 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TCN2 mRNA
CTD
PMID:23196670
NCBI chr11:3,867,077...3,882,078
Ensembl chr11:3,867,192...3,882,159
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Tcp11l2
t-complex 11 (mouse) like 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TCP11L2 mRNA
CTD
PMID:23196670
NCBI chr10:84,412,811...84,450,219
Ensembl chr10:84,412,490...84,450,223
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Tdo2
tryptophan 2,3-dioxygenase
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TDO2 mRNA
CTD
PMID:35618242
NCBI chr 3:81,865,719...81,883,035
Ensembl chr 3:81,864,397...81,883,509
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Tef
thyrotroph embryonic factor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TEF mRNA
CTD
PMID:23196670
NCBI chr15:81,686,874...81,711,064
Ensembl chr15:81,686,622...81,711,064
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Tenm3
teneurin transmembrane protein 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TENM3 mRNA
CTD
PMID:23146750
NCBI chr 8:48,678,700...51,370,255
Ensembl chr 8:48,680,717...49,296,986
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Tent5c
terminal nucleotidyltransferase 5C
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TENT5C mRNA
CTD
PMID:23196670
NCBI chr 3:100,375,373...100,396,508
Ensembl chr 3:100,358,944...100,396,640
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Terc
telomerase RNA component
multiple interactions decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TERC mRNA
CTD
PMID:26330309
NCBI chr 3:96,321,753...96,322,149
Ensembl chr 3:96,321,753...96,322,149
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Terf1
telomeric repeat binding factor 1
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TERF1 mRNA 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TERF1 mRNA
CTD
PMID:26330309
NCBI chr 1:15,875,634...15,914,283
Ensembl chr 1:15,875,870...15,914,276
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Terf2
telomeric repeat binding factor 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TERF2 mRNA
CTD
PMID:26330309
NCBI chr 8:107,796,032...107,823,180
Ensembl chr 8:107,796,032...107,823,179
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Tert
telomerase reverse transcriptase
multiple interactions decreases expression decreases activity
ISO
3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of TERT protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TERT mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of TERT protein
CTD
PMID:26330309
NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962
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Tex2
testis expressed gene 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TEX2 mRNA
CTD
PMID:32119087
NCBI chr11:106,392,965...106,504,259
Ensembl chr11:106,392,973...106,504,249
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Tfpi2
tissue factor pathway inhibitor 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TFPI2 mRNA
CTD
PMID:29947894
NCBI chr 6:3,962,589...3,988,977
Ensembl chr 6:3,962,595...3,988,919
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Tgfb2
transforming growth factor, beta 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TGFB2 mRNA
CTD
PMID:23196670
NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186
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Tgfb3
transforming growth factor, beta 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TGFB3 mRNA
CTD
PMID:23196670
NCBI chr12:86,103,517...86,125,815
Ensembl chr12:86,103,519...86,125,815
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Tgfbi
transforming growth factor, beta induced
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TGFBI mRNA
CTD
PMID:22262711
NCBI chr13:56,757,399...56,787,172
Ensembl chr13:56,757,336...56,787,375
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Tgm2
transglutaminase 2, C polypeptide
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TGM2 mRNA
CTD
PMID:23196670
NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356
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Thbd
thrombomodulin
affects expression increases expression multiple interactions
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of THBD mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of THBD protein [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of THBD protein
CTD
PMID:20702594 PMID:28973532
NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108
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Thop1
thimet oligopeptidase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of THOP1 mRNA
CTD
PMID:32119087
NCBI chr10:80,905,917...80,918,194
Ensembl chr10:80,905,869...80,918,393
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Thrb
thyroid hormone receptor beta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of THRB mRNA
CTD
PMID:20959002
NCBI chr14:4,429,599...4,810,538
Ensembl chr14:4,431,611...4,809,435
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Thy1
thymus cell antigen 1, theta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of THY1 mRNA
CTD
PMID:23196670
NCBI chr 9:43,954,681...43,959,876
Ensembl chr 9:43,954,681...43,959,876
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Timp1
tissue inhibitor of metalloproteinase 1
multiple interactions increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TIMP1 mRNA
CTD
PMID:28163111 PMID:28973532 PMID:35618242
NCBI chr X:20,736,524...20,740,972
Ensembl chr X:20,736,405...20,740,974
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Timp3
tissue inhibitor of metalloproteinase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TIMP3 mRNA
CTD
PMID:23196670 PMID:35618242
NCBI chr10:86,136,276...86,185,369
Ensembl chr10:86,136,236...86,185,370
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Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
affects expression increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TIPARP mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TIPARP mRNA
CTD
PMID:18042819 PMID:19692669 PMID:20702594 PMID:23146750 PMID:23994337 PMID:29738842 PMID:29947894 PMID:32119087 More...
NCBI chr 3:65,435,868...65,462,939
Ensembl chr 3:65,435,831...65,462,939
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Tjp1
tight junction protein 1
decreases expression multiple interactions
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein acetovanillone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein] 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [TJP1 protein binds to OCLN protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein
CTD
PMID:20064788 PMID:20299304 PMID:37598416
NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
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Tkfc
triokinase, FMN cyclase
decreases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TKFC mRNA
CTD
PMID:20959002 PMID:23994337
NCBI chr19:10,565,153...10,583,257
Ensembl chr19:10,565,155...10,583,018
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Tlr4
toll-like receptor 4
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TLR4 mRNA
CTD
PMID:21703328
NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
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Tlr6
toll-like receptor 6
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TLR6 mRNA
CTD
PMID:23146750
NCBI chr 5:65,109,373...65,128,387
Ensembl chr 5:65,109,374...65,117,440
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Tm7sf2
transmembrane 7 superfamily member 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TM7SF2 mRNA
CTD
PMID:23196670
NCBI chr19:6,112,851...6,117,880
Ensembl chr19:6,112,851...6,118,403
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Tmem100
transmembrane protein 100
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMEM100 mRNA
CTD
PMID:23196670
NCBI chr11:89,921,174...89,927,334
Ensembl chr11:89,921,174...89,927,334
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Tmem138
transmembrane protein 138
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TMEM138 mRNA
CTD
PMID:23196670
NCBI chr19:10,547,842...10,554,765
Ensembl chr19:10,547,842...10,554,726
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Tmem150c
transmembrane protein 150C
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of TMEM150C mRNA
CTD
PMID:30744511
NCBI chr 5:100,225,731...100,313,463
Ensembl chr 5:100,225,731...100,307,667
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Tmem176b
transmembrane protein 176B
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMEM176B mRNA
CTD
PMID:23196670
NCBI chr 6:48,810,745...48,818,363
Ensembl chr 6:48,810,752...48,818,430
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Tmem200a
transmembrane protein 200A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TMEM200A mRNA
CTD
PMID:32119087
NCBI chr10:25,867,080...25,955,713
Ensembl chr10:25,788,229...25,954,950
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Tmem204
transmembrane protein 204
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMEM204 mRNA
CTD
PMID:23196670
NCBI chr17:25,276,676...25,300,088
Ensembl chr17:25,276,676...25,302,565
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Tmem236
transmembrane protein 236
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMEM236 mRNA
CTD
PMID:32119087
NCBI chr 2:14,179,335...14,226,804
Ensembl chr 2:14,179,334...14,226,804
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Tmem254
transmembrane protein 254
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TMEM254 mRNA
CTD
PMID:23196670
NCBI chr14:25,923,722...25,928,096
Ensembl chr14:25,923,724...25,928,096
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Tmem37
transmembrane protein 37
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMEM37 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TMEM37 mRNA
CTD
PMID:23146750 PMID:32119087
NCBI chr 1:119,995,106...120,001,799
Ensembl chr 1:119,995,107...120,001,804
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Tmem47
transmembrane protein 47
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMEM47 mRNA
CTD
PMID:19692669
NCBI chr X:80,114,250...80,141,481
Ensembl chr X:80,114,304...80,141,478
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Tmem97
transmembrane protein 97
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TMEM97 mRNA
CTD
PMID:23196670
NCBI chr11:78,432,643...78,441,561
Ensembl chr11:78,432,643...78,441,603
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Tmod1
tropomodulin 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TMOD1 mRNA
CTD
PMID:19692669
NCBI chr 4:46,038,940...46,116,032
Ensembl chr 4:46,038,935...46,116,032
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Tmt1b
thiol methyltransferase 1B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of METTL7B mRNA
CTD
PMID:19692669
NCBI chr10:128,794,146...128,796,857
Ensembl chr10:128,794,143...128,796,857
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Tnf
tumor necrosis factor
multiple interactions decreases expression increases expression increases secretion decreases secretion
ISO EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with TNF protein] results in increased expression of CCNA2 mRNA; TNF protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TNF mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF protein [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF protein; [Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of TNF mRNA; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF protein] 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of TNF protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF mRNA]; 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of TNF protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased secretion of TNF protein
CTD
PMID:17557910 PMID:25433332 PMID:28163111 PMID:28973532 PMID:30768972 PMID:31563530 PMID:35618242 PMID:37598416 More...
NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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Tnfaip2
tumor necrosis factor, alpha-induced protein 2
increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFAIP2 mRNA
CTD
PMID:19692669 PMID:23994337
NCBI chr12:111,408,898...111,421,452
Ensembl chr12:111,408,903...111,421,452
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Tnfaip3
tumor necrosis factor, alpha-induced protein 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFAIP3 mRNA
CTD
PMID:35618242
NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405
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Tnfaip6
tumor necrosis factor alpha induced protein 6
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFAIP6 mRNA
CTD
PMID:35618242
NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698
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Tnfaip8l3
tumor necrosis factor, alpha-induced protein 8-like 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFAIP8L3 mRNA
CTD
PMID:32119087
NCBI chr 9:53,932,890...53,975,695
Ensembl chr 9:53,930,689...53,975,672
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Tnfrsf11b
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFRSF11B mRNA
CTD
PMID:22262711 PMID:28351761 PMID:34256052
NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880
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Tnfrsf13b
tumor necrosis factor receptor superfamily, member 13b
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TNFRSF13B mRNA
CTD
PMID:32119087
NCBI chr11:61,017,567...61,040,435
Ensembl chr11:61,017,581...61,040,198
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Tnfrsf21
tumor necrosis factor receptor superfamily, member 21
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFRSF21 mRNA
CTD
PMID:20959002
NCBI chr17:43,327,446...43,400,079
Ensembl chr17:43,327,446...43,400,080
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Tnfrsf9
tumor necrosis factor receptor superfamily, member 9
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFRSF9 mRNA
CTD
PMID:35618242
NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559
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Tnfsf10
tumor necrosis factor (ligand) superfamily, member 10
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNFSF10 mRNA
CTD
PMID:34256052
NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
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Tnfsf13
tumor necrosis factor (ligand) superfamily, member 13
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TNFSF13 mRNA
CTD
PMID:23196670
NCBI chr11:69,573,403...69,576,380
Ensembl chr11:69,573,672...69,576,610
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Tnfsf14
tumor necrosis factor (ligand) superfamily, member 14
affects expression
ISO
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TNFSF14 mRNA
CTD
PMID:21703328
NCBI chr17:57,496,437...57,501,182
Ensembl chr17:57,496,492...57,501,177
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Tnnt3
troponin T3, skeletal, fast
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNNT3 mRNA
CTD
PMID:32119087
NCBI chr 7:142,052,530...142,069,746
Ensembl chr 7:142,052,573...142,069,746
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Tpm1
tropomyosin 1, alpha
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TPM1 mRNA
CTD
PMID:19692669
NCBI chr 9:66,929,872...66,956,954
Ensembl chr 9:66,929,872...66,956,688
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Tpra1
transmembrane protein, adipocyte asscociated 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TPRA1 mRNA
CTD
PMID:19692669
NCBI chr 6:88,879,238...88,889,216
Ensembl chr 6:88,879,233...88,889,220
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Tprn
taperin
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TPRN mRNA
CTD
PMID:23196670
NCBI chr 2:25,152,610...25,159,898
Ensembl chr 2:25,152,630...25,159,897
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Tpt1
tumor protein, translationally-controlled 1
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in decreased expression of TPT1 mRNA
CTD
PMID:30744511
NCBI chr14:76,082,771...76,085,743
Ensembl chr14:76,082,533...76,085,965
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Tram2
translocating chain-associating membrane protein 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRAM2 mRNA
CTD
PMID:23146750
NCBI chr 1:21,071,621...21,149,449
Ensembl chr 1:21,066,523...21,149,453
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Trib2
tribbles pseudokinase 2
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRIB2 mRNA
CTD
PMID:32119087
NCBI chr12:15,841,726...15,866,963
Ensembl chr12:15,841,728...15,866,923
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Trib3
tribbles pseudokinase 3
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRIB3 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TRIB3 mRNA
CTD
PMID:20959002 PMID:22262711
NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
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Tril
TLR4 interactor with leucine-rich repeats
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TRIL mRNA
CTD
PMID:32119087
NCBI chr 6:53,792,453...53,797,810
Ensembl chr 6:53,792,453...53,797,815
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Trim15
tripartite motif-containing 15
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TRIM15 mRNA
CTD
PMID:29947894
NCBI chr17:37,171,582...37,179,066
Ensembl chr17:37,171,583...37,178,102
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Trim47
tripartite motif-containing 47
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRIM47 mRNA
CTD
PMID:32119087
NCBI chr11:115,996,576...116,001,061
Ensembl chr11:115,996,578...116,018,036
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Trim63
tripartite motif-containing 63
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRIM63 mRNA
CTD
PMID:23196670
NCBI chr 4:134,042,431...134,056,940
Ensembl chr 4:134,042,431...134,056,940
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Trip13
thyroid hormone receptor interactor 13
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TRIP13 mRNA
CTD
PMID:23196670
NCBI chr13:74,060,577...74,085,855
Ensembl chr13:74,059,466...74,085,903
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Trp53
transformation related protein 53
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TP53 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TP53 protein 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene affects the localization of TP53 protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased expression of TP53 protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [leptomycin B results in increased expression of TP53 protein]
CTD
PMID:19751709 PMID:20840854 PMID:21703328
NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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Trp53inp1
transformation related protein 53 inducible nuclear protein 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRP53INP1 mRNA
CTD
PMID:23196670
NCBI chr 4:11,156,441...11,174,379
Ensembl chr 4:11,156,431...11,174,379
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Trpc4
transient receptor potential cation channel, subfamily C, member 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRPC4 mRNA
CTD
PMID:32119087
NCBI chr 3:54,063,441...54,225,892
Ensembl chr 3:54,063,456...54,225,892
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Trpm5
transient receptor potential cation channel, subfamily M, member 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TRPM5 mRNA
CTD
PMID:32119087
NCBI chr 7:142,625,266...142,648,379
Ensembl chr 7:142,622,890...142,648,379
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Trpv1
transient receptor potential cation channel, subfamily V, member 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TRPV1 mRNA
CTD
PMID:32119087
NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068
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Trpv5
transient receptor potential cation channel, subfamily V, member 5
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Cholecalciferol] results in increased expression of TRPV5 mRNA
CTD
PMID:31820026
NCBI chr 6:41,628,595...41,658,158
Ensembl chr 6:41,629,107...41,657,703
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Trpv6
transient receptor potential cation channel, subfamily V, member 6
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Cholecalciferol] results in decreased expression of TRPV6 mRNA
CTD
PMID:31820026
NCBI chr 6:41,597,553...41,613,339
Ensembl chr 6:41,597,558...41,613,339
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Tsc22d1
TSC22 domain family, member 1
decreases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TSC22D1 mRNA [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of TSC22D1 mRNA
CTD
PMID:16984957 PMID:19692669 PMID:20959002
NCBI chr14:76,652,401...76,745,205
Ensembl chr14:76,652,401...76,745,205
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Tshb
thyroid stimulating hormone, beta subunit
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TSHB protein
CTD
PMID:17379623
NCBI chr 3:102,684,621...102,718,175
Ensembl chr 3:102,682,781...102,690,034
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Tsku
tsukushi, small leucine rich proteoglycan
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TSKU mRNA
CTD
PMID:20702594
NCBI chr 7:97,999,875...98,010,602
Ensembl chr 7:97,999,875...98,010,535
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Tsnax
translin-associated factor X
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TSNAX mRNA
CTD
PMID:19692669
NCBI chr 8:125,739,780...125,760,947
Ensembl chr 8:125,739,736...125,760,931
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Tspan5
tetraspanin 5
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TSPAN5 mRNA
CTD
PMID:23196670
NCBI chr 3:138,447,609...138,610,194
Ensembl chr 3:138,447,956...138,613,666
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Tspan7
tetraspanin 7
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TSPAN7 mRNA
CTD
PMID:23994337
NCBI chr X:10,351,355...10,462,843
Ensembl chr X:10,351,397...10,462,844
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Tspan8
tetraspanin 8
decreases expression increases expression
ISO EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TSPAN8 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TSPAN8 mRNA
CTD
PMID:23196670 PMID:23994337
NCBI chr10:115,652,722...115,685,798
Ensembl chr10:115,652,737...115,685,798
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Tspo
translocator protein
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TSPO mRNA
CTD
PMID:20959002
NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404
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Tspyl4
TSPY-like 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TSPYL4 mRNA
CTD
PMID:23196670
NCBI chr10:34,173,417...34,177,316
Ensembl chr10:34,173,438...34,177,316
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Tst
thiosulfate sulfurtransferase, mitochondrial
decreases expression increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TST mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TST mRNA
CTD
PMID:23196670 PMID:32119087
NCBI chr15:78,283,756...78,290,065
Ensembl chr15:78,283,756...78,290,107
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Ttc4
tetratricopeptide repeat domain 4
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TTC4 mRNA
CTD
PMID:23196670
NCBI chr 4:106,514,952...106,536,188
Ensembl chr 4:106,519,453...106,536,141
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Ttl
tubulin tyrosine ligase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TTL mRNA
CTD
PMID:23196670
NCBI chr 2:128,907,867...128,938,203
Ensembl chr 2:128,907,862...128,938,203
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Tub
TUB bipartite transcription factor
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TUB mRNA
CTD
PMID:23146750
NCBI chr 7:108,610,087...108,633,666
Ensembl chr 7:108,549,545...108,633,667
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Tuba4a
tubulin, alpha 4A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TUBA4A mRNA
CTD
PMID:20959002
NCBI chr 1:75,190,867...75,197,905
Ensembl chr 1:75,190,872...75,196,509
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Tubb2b
tubulin, beta 2B class IIB
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TUBB2B mRNA
CTD
PMID:32119087
NCBI chr13:34,310,991...34,314,337
Ensembl chr13:34,310,731...34,314,449
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Tubb5
tubulin, beta 5 class I
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TUBB5 mRNA
CTD
PMID:37080397
NCBI chr17:36,144,812...36,149,193
Ensembl chr17:36,144,813...36,149,198
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Txn2
thioredoxin 2
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] results in increased expression of TXN2 mRNA
CTD
PMID:24378064
NCBI chr15:77,799,251...77,813,194
Ensembl chr15:77,799,247...77,813,206
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Txnip
thioredoxin interacting protein
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TXNIP mRNA
CTD
PMID:19692669
NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199
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Txnl4a
thioredoxin-like 4A
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TXNL4A mRNA
CTD
PMID:23994337
NCBI chr18:80,250,041...80,269,066
Ensembl chr18:80,249,980...80,255,956 Ensembl chr18:80,249,980...80,255,956
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Txnrd1
thioredoxin reductase 1
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of TXNRD1 mRNA
CTD
PMID:24378064
NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
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Txnrd2
thioredoxin reductase 2
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of TXNRD2 mRNA
CTD
PMID:37080397
NCBI chr16:18,245,167...18,297,823
Ensembl chr16:18,245,134...18,297,823
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Tyro3
TYRO3 protein tyrosine kinase 3
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TYRO3 mRNA
CTD
PMID:23196670
NCBI chr 2:119,628,123...119,648,585
Ensembl chr 2:119,628,214...119,648,585
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Ube2q2
ubiquitin-conjugating enzyme E2Q family member 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UBE2Q2 mRNA
CTD
PMID:23146750
NCBI chr 9:55,056,602...55,114,813
Ensembl chr 9:55,056,138...55,114,813
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Uchl5
ubiquitin carboxyl-terminal esterase L5
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UCHL5 mRNA
CTD
PMID:23196670
NCBI chr 1:143,652,993...143,683,204
Ensembl chr 1:143,653,010...143,683,204
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Ugcg
UDP-glucose ceramide glucosyltransferase
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UGCG mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of UGCG mRNA
CTD
PMID:19692669 PMID:23196670 PMID:29947894
NCBI chr 4:59,189,452...59,222,833
Ensembl chr 4:59,189,257...59,222,833
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Ugdh
UDP-glucose dehydrogenase
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of UGDH protein
CTD
PMID:23457121
NCBI chr 5:65,570,550...65,593,185
Ensembl chr 5:65,570,564...65,593,292
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Ugt1a1
UDP glucuronosyltransferase 1 family, polypeptide A1
increases expression decreases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UGT1A1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of UGT1A1 mRNA
CTD
PMID:19144771 PMID:19692669 PMID:20959002 PMID:26770886
NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
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Ugt1a2
UDP glucuronosyltransferase 1 family, polypeptide A2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UGT1A3 mRNA
CTD
PMID:29947894
NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719
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Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6B
increases expression
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UGT1A6 mRNA
CTD
PMID:19144771 PMID:19692669 PMID:20959002
NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725
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Ugt1a9
UDP glucuronosyltransferase 1 family, polypeptide A9
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UGT1A9 mRNA
CTD
PMID:19144771
NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719
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Ugt2b35
UDP glucuronosyltransferase 2 family, polypeptide B35
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UGT2B35 mRNA
CTD
PMID:19144771
NCBI chr 5:87,148,719...87,161,133
Ensembl chr 5:87,148,719...87,161,134
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Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UHRF1 mRNA
CTD
PMID:23196670
NCBI chr17:56,610,405...56,630,486
Ensembl chr17:56,610,321...56,630,486
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Ung
uracil DNA glycosylase
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of UNG mRNA
CTD
PMID:20959002
NCBI chr 5:114,268,427...114,277,382
Ensembl chr 5:114,268,447...114,277,384
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Upb1
ureidopropionase, beta
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of UPB1 mRNA
CTD
PMID:19692669
NCBI chr10:75,242,745...75,277,513
Ensembl chr10:75,236,949...75,277,513
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Usp18
ubiquitin specific peptidase 18
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of USP18 mRNA
CTD
PMID:32119087
NCBI chr 6:121,222,865...121,247,876
Ensembl chr 6:121,222,865...121,247,876
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Usp22
ubiquitin specific peptidase 22
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of USP22 mRNA
CTD
PMID:32119087
NCBI chr11:61,042,607...61,065,885
Ensembl chr11:61,042,611...61,065,881
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Utp25
UTP25 small subunit processome component
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UTP25 mRNA
CTD
PMID:23994337
NCBI chr 1:192,786,707...192,812,603
Ensembl chr 1:192,773,412...192,812,580
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Utrn
utrophin
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of UTRN mRNA
CTD
PMID:23196670
NCBI chr10:12,257,931...12,745,632
Ensembl chr10:12,257,932...12,745,109
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Uvrag
UV radiation resistance associated gene
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of UVRAG mRNA
CTD
PMID:23994337
NCBI chr 7:98,535,949...98,790,373
Ensembl chr 7:98,534,228...98,790,348
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Vcam1
vascular cell adhesion molecule 1
multiple interactions decreases expression increases expression affects expression
EXP ISO
CAV1 gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein] 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of VCAM1 mRNA 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein 3,4,5,3',4'-pentachlorobiphenyl affects the expression of VCAM1 mRNA
CTD
PMID:20406653 PMID:22262711 PMID:23196670 PMID:24709675 PMID:26519613 PMID:37080397 More...
NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
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Vcan
versican
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAN mRNA
CTD
PMID:35618242
NCBI chr13:89,803,429...89,891,146
Ensembl chr13:89,803,431...89,890,628
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Vegfa
vascular endothelial growth factor A
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VEGFA mRNA
CTD
PMID:28351761
NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
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Vegfc
vascular endothelial growth factor C
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VEGFC mRNA
CTD
PMID:23196670
NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131
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Vegfd
vascular endothelial growth factor D
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of VEGFD mRNA
CTD
PMID:23196670
NCBI chr X:163,156,282...163,185,643
Ensembl chr X:163,156,374...163,185,646
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Vil1
villin 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIL1 mRNA
CTD
PMID:23146750
NCBI chr 1:74,448,543...74,474,719
Ensembl chr 1:74,448,535...74,474,718
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Vim
vimentin
increases expression multiple interactions
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]; AHR mRNA promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]; fulvestrant inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]; PKM protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]; WP1066 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]
CTD
PMID:23196670 PMID:28284859
NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
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Vrk1
vaccinia related kinase 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VRK1 mRNA
CTD
PMID:23196670
NCBI chr12:105,976,398...106,044,578
Ensembl chr12:105,976,487...106,043,685 Ensembl chr12:105,976,487...106,043,685
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Vrk3
vaccinia related kinase 3
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VRK3 mRNA
CTD
PMID:19692669
NCBI chr 7:44,398,049...44,426,939
Ensembl chr 7:44,397,837...44,426,939
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Vwa5a
von Willebrand factor A domain containing 5A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of VWA5A mRNA
CTD
PMID:23196670
NCBI chr 9:38,629,564...38,654,633
Ensembl chr 9:38,629,564...38,654,633
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Wdr45
WD repeat domain 45
decreases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of WDR45 mRNA
CTD
PMID:23994337
NCBI chr X:7,588,212...7,594,439
Ensembl chr X:7,580,572...7,594,445
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Wdr76
WD repeat domain 76
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of WDR76 mRNA
CTD
PMID:23146750
NCBI chr 2:121,337,204...121,375,341
Ensembl chr 2:121,337,204...121,375,341
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Wdr86
WD repeat domain 86
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of WDR86 mRNA
CTD
PMID:32119087
NCBI chr 5:24,901,898...24,935,696
Ensembl chr 5:24,916,736...24,935,725
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Wfdc18
WAP four-disulfide core domain 18
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of WFDC18 mRNA
CTD
PMID:23196670
NCBI chr11:83,599,830...83,602,186
Ensembl chr11:83,599,841...83,602,174
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Wnk4
WNK lysine deficient protein kinase 4
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of WNK4 mRNA
CTD
PMID:23196670
NCBI chr11:101,151,363...101,168,235
Ensembl chr11:101,151,393...101,168,235
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Wnt5a
wingless-type MMTV integration site family, member 5A
increases expression decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of WNT5A mRNA 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of WNT5A mRNA
CTD
PMID:22262711 PMID:23196670 PMID:35618242
NCBI chr14:28,224,962...28,249,405
Ensembl chr14:28,226,707...28,249,405
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Wnt7b
wingless-type MMTV integration site family, member 7B
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of WNT7B mRNA
CTD
PMID:29947894
NCBI chr15:85,419,638...85,466,022
Ensembl chr15:85,419,638...85,466,674
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Wrnip1
Werner helicase interacting protein 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of WRNIP1 mRNA
CTD
PMID:23196670
NCBI chr13:32,986,013...33,006,593
Ensembl chr13:32,986,021...33,006,592
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Xaf1
XIAP associated factor 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of XAF1 mRNA
CTD
PMID:23146750
NCBI chr11:72,192,229...72,204,560
Ensembl chr11:72,192,455...72,204,559
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Xbp1
X-box binding protein 1
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of XBP1 mRNA
CTD
PMID:37080397
NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
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Xcr1
chemokine (C motif) receptor 1
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of XCR1 mRNA
CTD
PMID:32119087
NCBI chr 9:123,681,380...123,691,094
Ensembl chr 9:123,681,380...123,691,094
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Xdh
xanthine dehydrogenase
increases expression multiple interactions
EXP ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of XDH mRNA AHR gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of XDH mRNA]
CTD
PMID:23994337 PMID:34256052
NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191
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Xpa
xeroderma pigmentosum, complementation group A
multiple interactions increases expression
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Benzo(a)pyrene] results in decreased expression of XPA protein 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of XPA protein
CTD
PMID:19553035
NCBI chr 4:46,175,222...46,196,317
Ensembl chr 4:46,155,347...46,196,311
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Xpc
xeroderma pigmentosum, complementation group C
multiple interactions
ISO
[3,4,5,3',4'-pentachlorobiphenyl co-treated with Benzo(a)pyrene] results in decreased expression of XPC protein
CTD
PMID:19553035
NCBI chr 6:91,466,287...91,492,870
Ensembl chr 6:91,466,287...91,492,870
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Ypel1
yippee like 1
increases expression
EXP
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of YPEL1 mRNA
CTD
PMID:23994337
NCBI chr16:16,887,454...16,904,912
Ensembl chr16:16,887,560...16,904,909
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Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of YWHAB protein
CTD
PMID:23457121
NCBI chr 2:163,837,082...163,860,508
Ensembl chr 2:163,836,880...163,860,508
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Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
multiple interactions
EXP
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of YWHAZ protein
CTD
PMID:23457121
NCBI chr15:36,770,505...36,803,228
Ensembl chr15:36,771,014...36,797,173
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Zcchc12
zinc finger, CCHC domain containing 12
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ZCCHC12 mRNA
CTD
PMID:23196670
NCBI chr X:35,459,553...35,462,817
Ensembl chr X:35,459,557...35,462,811
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Zdhhc2
zinc finger, DHHC domain containing 2
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ZDHHC2 mRNA
CTD
PMID:23196670
NCBI chr 8:40,876,526...40,946,178
Ensembl chr 8:40,876,856...40,963,309
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Zfp219
zinc finger protein 219
affects expression
EXP
3,4,5,3',4'-pentachlorobiphenyl affects the expression of ZFP219 mRNA
CTD
PMID:23994337
NCBI chr14:52,243,532...52,258,597
Ensembl chr14:52,243,534...52,258,190
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Zfp334
zinc finger protein 334
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ZFP334 mRNA
CTD
PMID:32119087
NCBI chr 2:165,216,184...165,230,234
Ensembl chr 2:165,216,184...165,230,179
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Zfp354a
zinc finger protein 354A
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ZFP354A mRNA
CTD
PMID:20959002
NCBI chr11:50,950,052...50,963,626
Ensembl chr11:50,950,084...50,963,626
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Zfp367
zinc finger protein 367
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ZFP367 mRNA
CTD
PMID:23196670
NCBI chr13:64,280,836...64,301,013
Ensembl chr13:64,280,832...64,301,016
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Zfp395
zinc finger protein 395
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ZNF395 mRNA
CTD
PMID:19692669
NCBI chr14:65,595,796...65,636,379
Ensembl chr14:65,595,838...65,636,379
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Zfp473
zinc finger protein 473
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ZFP473 mRNA
CTD
PMID:32119087
NCBI chr 7:44,380,904...44,398,041
Ensembl chr 7:44,380,904...44,400,474
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Zfp697
zinc finger protein 697
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ZNF697 mRNA
CTD
PMID:23146750
NCBI chr 3:98,289,278...98,508,893
Ensembl chr 3:98,289,777...98,661,128
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Zfp784
zinc finger protein 784
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ZNF784 mRNA
CTD
PMID:23146750
NCBI chr 7:5,037,445...5,041,445
Ensembl chr 7:5,037,438...5,041,445
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Zfp997
zinc finger protein 997
increases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CXCL5 mRNA
CTD
PMID:19692669
NCBI chr13:66,258,188...66,271,523
Ensembl chr13:66,261,294...66,271,953
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Znfx1
zinc finger, NFX1-type containing 1
decreases expression
ISO
3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ZNFX1 mRNA
CTD
PMID:32119087
NCBI chr 2:166,877,713...166,904,926
Ensembl chr 2:166,877,713...166,904,935
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