Bax (BCL2-associated X protein) - Rat Genome Database

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Gene: Bax (BCL2-associated X protein) Mus musculus
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Symbol: Bax
Name: BCL2-associated X protein
RGD ID: 10226
MGI Page MGI
Description: Enables Hsp70 protein binding activity and identical protein binding activity. Involved in positive regulation of neuron apoptotic process. Acts upstream of or within several processes, including apoptotic signaling pathway; mitochondrion organization; and regulation of apoptotic process. Located in cytosol; endoplasmic reticulum; and mitochondrial outer membrane. Part of BAX complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; ataxia telangiectasia; colon adenocarcinoma; and colorectal cancer. Orthologous to human BAX (BCL2 associated X, apoptosis regulator).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: apoptosis regulator BAX
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,111,124 - 45,116,332 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,111,121 - 45,116,322 (-)EnsemblGRCm39 Ensembl
GRCm38745,461,695 - 45,466,903 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,461,697 - 45,466,898 (-)EnsemblGRCm38mm10GRCm38
MGSCv37752,717,065 - 52,722,268 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,329,744 - 45,334,864 (-)NCBIMGSCv36mm8
Celera740,917,745 - 40,922,946 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal obesity-metabolic syndrome 1  (ISO)
acute kidney failure  (ISO)
Acute Lung Injury  (ISO)
acute lymphoblastic leukemia  (ISO)
acute myocardial infarction  (ISO)
Adrenal Insufficiency  (ISO)
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis  (IEP,IMP)
anti-basement membrane glomerulonephritis  (ISO)
ataxia telangiectasia  (ISO)
brain glioma  (ISO)
Brain Hypoxia-Ischemia  (ISO)
Brain Injuries  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
bronchopulmonary dysplasia  (ISO)
Burns  (ISO)
Cerebral Hemorrhage  (ISO)
cervical squamous cell carcinoma  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chronic Intermittent Hypoxia  (ISO)
clear cell renal cell carcinoma  (ISO)
colon adenocarcinoma  (ISO)
colon carcinoma  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
congestive heart failure  (ISO)
dementia  (ISO)
depressive disorder  (ISO)
Diabetic Cardiomyopathies  (IEP)
dilated cardiomyopathy  (ISO)
endometriosis  (ISO)
Endotoxemia  (ISO)
Esophageal Neoplasms  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Mammary Neoplasms  (ISO)
Fetal Growth Retardation  (ISO)
Gastrointestinal Hemorrhage  (ISO)
genetic disease  (ISO)
glaucoma  (ISO)
heart disease  (ISO)
hepatocellular carcinoma  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Huntington's disease  (ISO)
Hyperplasia  (IMP)
hypertension  (ISO)
impotence  (ISO)
intermittent claudication  (ISO)
intestinal disease  (ISO)
Intestinal Neoplasms  (ISO)
ischemia  (ISO)
Kashin-Beck Disease  (ISO)
Kidney Reperfusion Injury  (ISO)
Knee Osteoarthritis  (ISO)
leiomyoma  (ISO)
Liver Reperfusion Injury  (IEP,ISO)
Lung Injury  (ISO)
lung non-small cell carcinoma  (ISO)
Lung Reperfusion Injury  (IEP,ISO)
macular degeneration  (ISO)
male infertility  (IMP,ISO)
Microsatellite Instability  (ISO)
middle cerebral artery infarction  (ISO)
morphine dependence  (ISO)
Multi-Infarct Dementia  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
Neoplasm Metastasis  (ISO)
Nerve Degeneration  (ISO)
Optic Nerve Injuries  (ISO)
osteoarthritis  (ISO)
osteoporosis  (ISO)
polycystic ovary syndrome  (ISO)
post-traumatic stress disorder  (ISO)
Postoperative Cognitive Dysfunction  (ISO)
pre-malignant neoplasm  (ISO)
Premature Aging  (IEP)
primary cutaneous T-cell non-Hodgkin lymphoma  (ISO)
prion disease  (IMP)
prostate cancer  (ISO)
prostate carcinoma  (ISO)
Prostatic Neoplasms  (IEP,ISO)
Reperfusion Injury  (ISO)
Retina Reperfusion Injury  (ISO)
retinal degeneration  (ISO)
rheumatic heart disease  (ISO)
Right Ventricular Hypertrophy  (ISO)
Sarcopenia  (ISO)
scrapie  (IEP)
Spinal Cord Injuries  (ISO)
status epilepticus  (ISO)
stomach cancer  (ISO)
T-cell acute lymphoblastic leukemia  (ISO)
teratoma  (ISO)
Testis Reperfusion Injury  (ISO)
thyroiditis  (ISO)
toxoplasmosis  (ISO)
transient cerebral ischemia  (ISO)
Transplant Rejection  (ISO)
type 2 diabetes mellitus  (ISO)
urinary bladder cancer  (ISO)
Ventricular Remodeling  (IEP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-(S)-ar-turmerone  (ISO)
(+)-catechin  (ISO)
(+)-dexrazoxane  (EXP)
(+)-pilocarpine  (ISO)
(+)-sesamin  (EXP,ISO)
(+)-taxifolin  (ISO)
(+)-Tetrandrine  (ISO)
(+)-trans-(S)-allethrin  (ISO)
(-)-anisomycin  (EXP)
(-)-bornyl-caffeate  (ISO)
(-)-citrinin  (EXP)
(-)-ephedrine  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(-)-gambogic acid  (ISO)
(-)-matairesinol  (ISO)
(-)-noscapine  (ISO)
(-)-selegiline  (EXP)
(1->4)-beta-D-glucan  (EXP)
(20S)-ginsenoside Rg3  (ISO)
(20S)-ginsenoside Rh2  (ISO)
(E)-thiamethoxam  (EXP)
(E,E)-germacrone  (ISO)
(R)-carnitine  (ISO)
(R)-lipoic acid  (EXP,ISO)
(R)-noradrenaline  (ISO)
(R)-salsolinol  (ISO)
(R,R)-tramadol  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(R,S)-Scoulerine  (ISO)
(S)-(-)-perillyl alcohol  (EXP)
(S)-amphetamine  (ISO)
(S)-colchicine  (ISO)
(S)-naringenin  (ISO)
(S)-nicotine  (EXP,ISO)
(S)-ropivacaine  (ISO)
(Z)-3-butylidenephthalide  (ISO)
(Z)-ligustilide  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (EXP)
1,2-dichloroethane  (EXP,ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1,3-dichloropropan-2-ol  (EXP)
1,3-dinitrobenzene  (EXP,ISO)
1,3-thiazolidine-2,4-dione  (ISO)
1,4-benzoquinone  (ISO)
1,4-naphthoquinone  (ISO)
1-(4'-hydroxy-3'-methoxyphenyl)-7-phenyl-3-heptanone  (ISO)
1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea  (ISO)
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine  (EXP,ISO)
1-hydroxy-1-norresistomycin  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
1-naphthyl isothiocyanate  (EXP,ISO)
1-nitropropane  (ISO)
1-nitropyrene  (ISO)
11-deoxycorticosterone  (ISO)
16,16-dimethylprostaglandin E2  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one  (ISO)
1H-pyrazole  (EXP)
2''-galloylhyperin  (ISO)
2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP,ISO)
2,4-diaminotoluene  (ISO)
2,4-dinitrotoluene  (ISO)
2,5-hexanedione  (ISO)
2,6-diaminotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one  (ISO)
2-acetamidofluorene  (EXP,ISO)
2-acetamidophenol  (ISO)
2-amino-2-deoxy-D-galactopyranose  (EXP,ISO)
2-aminoethoxydiphenylborane  (ISO)
2-chloroethanol  (ISO)
2-deoxy-D-glucose  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxy-17beta-estradiol  (EXP,ISO)
2-nitro-p-phenylenediamine  (ISO)
2-nitrofluorene  (ISO)
2-nitropropane  (ISO)
2-tert-butylhydroquinone  (EXP,ISO)
20-hydroxyecdysone  (ISO)
20-hydroxypregn-4-en-3-one  (ISO)
25-hydroxycholesterol  (ISO)
3',4',7-trihydroxyisoflavone  (ISO)
3',4'-dimethoxyflavone  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,3'-Dichlorobenzidine  (ISO)
3,3'-diindolylmethane  (ISO)
3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine  (ISO)
3,4-dihydroxybenzoic acid  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3,7-dihydropurine-6-thione  (EXP)
3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyladenine  (EXP,ISO)
3-methylcholanthrene  (ISO)
3-nitropropanoic acid  (ISO)
3-phenoxybenzoic acid  (ISO)
3-phenylprop-2-enal  (ISO)
4'-epidoxorubicin  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4,5,6,7-TETRABROMOBENZOTRIAZOLE  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-acetylaminofluorene  (ISO)
4-amino-1,8-naphthalimide  (ISO)
4-aminopyridine  (ISO)
4-hydroperoxycyclophosphamide  (EXP,ISO)
4-hydroxy-TEMPO  (EXP,ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester  (EXP)
4-Nerolidylcatechol  (ISO)
4-nitro-1,2-phenylenediamine  (ISO)
4-nitro-m-cresol  (EXP)
4-nitrophenol  (EXP)
4-nonylphenol  (ISO)
4-octylphenol  (EXP)
4-phenylbutyric acid  (EXP,ISO)
4-vinylcyclohexene dioxide  (ISO)
5-aminolevulinic acid  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (EXP)
5-bromo-2'-deoxyuridine  (EXP)
5-fluorouracil  (EXP,ISO)
5-Hydroxycapric acid  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
5-methoxypsoralen  (ISO)
6-bromoindirubin-3'-oxime  (EXP)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (EXP,ISO)
6alpha-methylprednisolone  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
7,8-dihydroxycoumarin  (EXP,ISO)
7-ketocholesterol  (ISO)
8'-apo-beta,psi-caroten-8'-al  (ISO)
8-Br-cAMP  (ISO)
8-OH-DPAT  (EXP)
9,10-anthraquinone  (ISO)
9,10-phenanthroquinone  (ISO)
9-aminoacridine  (ISO)
9-cis-retinoic acid  (ISO)
9-Methoxycamptothecin  (ISO)
[6]-Shogaol  (ISO)
abamectin  (ISO)
Abemaciclib  (ISO)
ABT-737  (ISO)
acadesine  (ISO)
acetaldehyde  (ISO)
acetamide  (ISO)
acetamiprid  (ISO)
acetic acid  (ISO)
acetochlor  (ISO)
acetylsalicylic acid  (EXP,ISO)
aconitine  (EXP,ISO)
acridine orange  (ISO)
acridine orange free base  (ISO)
acrolein  (EXP,ISO)
acrylamide  (EXP,ISO)
acrylonitrile  (EXP,ISO)
actinomycin D  (EXP,ISO)
adefovir pivoxil  (ISO)
adenosine  (ISO)
Adenosine, cyclic 3',5'-[hydrogen [p(s)]-phosphorothioate]  (ISO)
afatinib  (ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
agomelatine  (ISO)
AH23848  (ISO)
alachlor  (ISO)
alantolactone  (ISO)
alborixin  (ISO)
albuterol  (ISO)
aldehydo-D-glucose  (EXP,ISO)
alendronic acid  (ISO)
all-trans-acitretin  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
allethrin  (ISO)
allicin  (ISO)
allopurinol  (ISO)
alloxan  (ISO)
Allyl chloride  (ISO)
Aloe emodin  (ISO)
alpha-amanitin  (EXP)
alpha-D-galactose  (ISO)
alpha-mangostin  (ISO)
alpha-naphthoflavone  (ISO)
alpha-pinene  (ISO)
alpha-Zearalanol  (ISO)
Alpinetin  (ISO)
alpinumisoflavone  (ISO)
aluminium atom  (EXP,ISO)
aluminium(0)  (EXP,ISO)
alvocidib  (EXP,ISO)
amentoflavone  (EXP)
amidotrizoic acid  (ISO)
amifostine  (ISO)
amino acid  (EXP)
aminoguanidine  (ISO)
amiodarone  (ISO)
amitriptyline  (ISO)
amlexanox  (EXP)
amlodipine  (ISO)
ammonium chloride  (ISO)
Ammothamnine  (ISO)
amodiaquine  (ISO)
amosite asbestos  (ISO)
amphetamine  (EXP)
amphibole asbestos  (ISO)
ampicillin  (EXP)
amsacrine  (ISO)
andrographolide  (ISO)
Anemoside B4  (EXP)
anethole  (ISO)
angiotensin II  (ISO)
anthocyanin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
anthracene  (ISO)
antimony(0)  (EXP)
antimycin A  (EXP,ISO)
Antrocin  (ISO)
apigenin  (ISO)
apocynin  (EXP,ISO)
aprepitant  (ISO)
arachidonic acid  (ISO)
aristolochic acid A  (EXP,ISO)
Aroclor 1254  (EXP,ISO)
arotinoid acid  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
artesunate  (ISO)
asarone  (ISO)
asbestos  (ISO)
asiatic acid  (ISO)
asoxime chloride  (ISO)
aspartame  (EXP,ISO)
Aspidin  (ISO)
astaxanthin  (ISO)
astilbin  (ISO)
astragaloside IV  (ISO)
Atipamezole  (ISO)
atorvastatin calcium  (EXP,ISO)
Atranorin  (ISO)
atrasentan  (ISO)
atrazine  (EXP,ISO)
atropine  (ISO)
auranofin  (EXP)
aurantio-obtusin  (ISO)
aureusidin  (ISO)
Auriculasin  (ISO)
azadirachtin A  (ISO)
azide  (ISO)
azilsartan  (ISO)
Azoxymethane  (ISO)
azoxystrobin  (ISO)
bafilomycin A1  (ISO)
baicalein  (EXP,ISO)
baicalin  (EXP,ISO)
Bay-K-8644  (EXP)
beauvericin  (ISO)
benazepril  (ISO)
benomyl  (ISO)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
benzothiazoles  (ISO)
berberine  (ISO)
Berberrubine  (ISO)
Bergenin  (EXP,ISO)
beta-carotene  (ISO)
beta-D-fructofuranose 1,6-bisphosphate  (ISO)
beta-Elemonic acid  (ISO)
beta-ionone  (ISO)
beta-lapachone  (ISO)
Beta-Solamarine  (ISO)
Betanin  (ISO)
betaxolol  (ISO)
betulin  (ISO)
betulinic acid  (ISO)
Betulonic acid  (ISO)
bexarotene  (ISO)
bicalutamide  (ISO)
bifenthrin  (EXP)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bisphenol AF  (EXP)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP,ISO)
boric acid  (EXP,ISO)
boron atom  (ISO)
bortezomib  (ISO)
bosentan  (EXP)
brassinin  (ISO)
brazilin  (ISO)
bromocriptine  (ISO)
bromuconazole  (ISO)
brucine  (EXP,ISO)
Brusatol  (ISO)
bucladesine  (ISO)
bupivacaine  (EXP)
buprofezin  (ISO)
buserelin  (ISO)
buta-1,3-diene  (EXP)
butane  (ISO)
butein  (EXP)
Butralin  (ISO)
Butylbenzyl phthalate  (EXP)
butyric acid  (EXP,ISO)
C.I. Natural Red 20  (ISO)
cabazitaxel  (ISO)
cadmium acetate  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium nitrate  (ISO)
cadmium sulfide  (ISO)
cadmium telluride  (ISO)
caffeine  (EXP,ISO)
cajanol  (ISO)
calcidiol  (ISO)
Calcimycin  (ISO)
calcitriol  (EXP,ISO)
calcium oxalate  (ISO)
Calpeptin  (ISO)
calycosin-7-O-beta-D-glucoside  (EXP,ISO)
calyculin A  (ISO)
camalexin  (ISO)
camptothecin  (ISO)
candesartan  (ISO)
cannabidiol  (EXP,ISO)
cantharidin  (ISO)
capsaicin  (EXP,ISO)
capsazepine  (EXP)
captan  (EXP)
carbachol  (EXP)
carbamate ester  (EXP)
carbamazepine  (ISO)
carbendazim  (ISO)
CARBENOXOLONE  (EXP,ISO)
carbidopa  (EXP,ISO)
carbofuran  (ISO)
carbon disulfide  (EXP)
carbon nanotube  (EXP,ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
carboplatin  (ISO)
carmustine  (ISO)
carnosic acid  (EXP,ISO)
carnosine  (ISO)
Carnosol  (EXP)
carvacrol  (ISO)
carvedilol  (EXP,ISO)
casticin  (EXP,ISO)
CEDRELONE  (ISO)
cefalotin  (ISO)
cefotaxime  (ISO)
celastrol  (EXP,ISO)
celecoxib  (ISO)
ceric oxide  (ISO)
ceritinib  (ISO)
cetrorelix  (EXP,ISO)
chalcones  (ISO)
chelerythrine  (ISO)
chelidonine  (ISO)
chenodeoxycholic acid  (ISO)
Chikusetsusaponin-V  (ISO)
CHIR 99021  (ISO)
chitosan  (EXP,ISO)
chlorambucil  (ISO)
chlordecone  (EXP)
chloroacetaldehyde  (ISO)
chloroacetic acid  (EXP)
chlorogenic acid  (EXP,ISO)
chloroprocaine  (ISO)
chloroquine  (EXP,ISO)
chlorothalonil  (EXP,ISO)
chlorpyrifos  (EXP,ISO)
cholesterol  (EXP,ISO)
choline  (EXP)
chromium atom  (ISO)
chromium(3+) trichloride  (ISO)
chromium(6+)  (EXP,ISO)
chrysazin  (ISO)
chrysene  (EXP)
chrysin  (ISO)
chrysin 5,7-dimethyl ether  (ISO)
chrysophanol  (ISO)
cidofovir anhydrous  (ISO)
ciglitazone  (ISO)
cilnidipine  (ISO)
cilostazol  (ISO)
cimetidine  (EXP,ISO)
Cinobufagin  (ISO)
Cinobufotalin  (ISO)
ciprofloxacin  (ISO)
Cirsimarin  (ISO)
cisplatin  (EXP,ISO)
Citreoviridin  (EXP,ISO)
citric acid  (ISO)
citronellal  (ISO)
clavulone II  (ISO)
clobetasol  (EXP)
clodronic acid  (ISO)
clofibrate  (ISO)
clonazepam  (ISO)
clorgyline  (ISO)
clozapine  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
cobalt(2+) sulfate  (ISO)
cobicistat  (EXP)
cocaine  (EXP,ISO)
codeinone  (ISO)
coenzyme Q10  (EXP,ISO)
colistin  (EXP,ISO)
concanamycin A  (EXP)
conjugated linoleic acid  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (EXP,ISO)
copper(II) sulfate  (EXP,ISO)
coptisine  (ISO)
cordycepin  (ISO)
corilagin  (ISO)
corosolic acid  (EXP,ISO)
corticosterone  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (EXP,ISO)
crocin-1  (EXP,ISO)
crotonaldehyde  (ISO)
cryptolepine  (ISO)
crystal violet  (ISO)
CU-O LINKAGE  (EXP)
cucurbitacin B  (EXP,ISO)
cucurbitacin E  (ISO)
cudraflavone B  (ISO)
curcumin  (EXP,ISO)
cyanamide  (ISO)
Cyanoginosin  (ISO)
cycloastragenol  (ISO)
cyclohexanols  (ISO)
cycloheximide  (ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (EXP,ISO)
cyflufenamid  (ISO)
cyfluthrin  (ISO)
cyhalothrin  (ISO)
cylindrospermopsin  (ISO)
cypermethrin  (EXP,ISO)
cytarabine  (ISO)
cytochalasin B  (ISO)
D-fructofuranose 1,6-bisphosphate  (ISO)
D-glucose  (EXP,ISO)
D-mannitol  (ISO)
D-penicillamine  (EXP)
dactolisib  (ISO)
dantrolene  (EXP)
dapagliflozin  (ISO)
dapoxetine  (ISO)
DAPT  (ISO)
daunorubicin  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (EXP,ISO)
deferiprone  (ISO)
deguelin  (ISO)
dehydrocostus lactone  (ISO)
dehydroepiandrosterone  (ISO)
delphinidin  (ISO)
demethoxycurcumin  (ISO)
demethoxyfumitremorgin C  (ISO)
Dendrobine  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (EXP,ISO)
Deoxyschizandrin  (ISO)
desferrioxamine B  (ISO)
Destruxin B  (ISO)
dexamethasone  (EXP,ISO)
dexmedetomidine  (ISO)
dextran sulfate  (EXP)
dextromethorphan  (ISO)
Di-n-hexyl phthalate  (ISO)
Di-n-octyl phthalate  (EXP)
diallyl disulfide  (ISO)
Diallyl sulfide  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (EXP,ISO)
diazepam  (ISO)
diazinon  (EXP,ISO)
diazoxide  (EXP,ISO)
dibenz[a,h]anthracene  (EXP)
dibenzoylmethane  (EXP)
Dibromoacetonitrile  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichlorine  (ISO)
dichlorvos  (ISO)
dichromium trioxide  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
Dictamnine  (ISO)
dideuterium oxide  (ISO)
Didymin  (ISO)
dieckol  (EXP,ISO)
dieldrin  (ISO)
diepoxybutane  (ISO)
diethanolamine  (EXP,ISO)
diethyl phthalate  (EXP,ISO)
diethyl sulfate  (ISO)
diethylstilbestrol  (EXP,ISO)
difenoconazole  (ISO)
dihydroactinidiolide  (EXP,ISO)
diiodine  (ISO)
diisobutyl phthalate  (EXP)
Diisodecyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dimethomorph  (ISO)
Dimethyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
dimethylarsinic acid  (EXP,ISO)
dimethylarsinous acid  (ISO)
dioscin  (EXP,ISO)
diosgenin  (ISO)
diosmin  (EXP)
dioxygen  (EXP,ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (EXP)
diquat  (EXP,ISO)
disodium selenite  (EXP,ISO)
disulfiram  (ISO)
dithionite(2-)  (ISO)
dizocilpine maleate  (EXP,ISO)
dobutamine  (EXP)
Dodecyl gallate  (EXP)
domoic acid  (EXP,ISO)
donepezil hydrochloride  (EXP)
dopamine  (ISO)
dorsomorphin  (EXP,ISO)
doxazosin  (ISO)
doxorubicin  (EXP,ISO)
doxycycline  (EXP)
drimenol  (ISO)
ebselen  (ISO)
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  (ISO)
echinacoside  (EXP)
Echinocystic acid  (ISO)
edaravone  (ISO)
elemental boron  (ISO)
elemental selenium  (EXP,ISO)
ellagic acid  (ISO)
ellipticine  (ISO)
embelin  (ISO)
emodin  (ISO)
enalapril  (ISO)
endosulfan  (EXP,ISO)
entinostat  (EXP)
enzyme inhibitor  (ISO)
epichlorohydrin  (ISO)
epoxiconazole  (EXP)
epoxomicin  (EXP)
erdosteine  (EXP,ISO)
eriocitrin  (ISO)
eritoran  (EXP)
erlotinib hydrochloride  (ISO)
erythromycin estolate  (ISO)
esculetin  (ISO)
esketamine  (ISO)
ethanol  (EXP,ISO)
Ethyl icosapentate  (EXP)
ethyl methanesulfonate  (ISO)
ethylbenzene  (ISO)
ethylene glycol  (ISO)
etoposide  (EXP,ISO)
eugenol  (EXP)
EUK-134  (ISO)
everolimus  (ISO)
Evodiamine  (ISO)
excitatory amino acid agonist  (EXP,ISO)
farrerol  (ISO)
fasudil  (ISO)
favipiravir  (ISO)
febuxostat  (ISO)
fenbendazole  (ISO)
fenhexamid  (ISO)
fenitrothion  (ISO)
fenofibrate  (ISO)
fenpyroximate  (ISO)
fenthion  (EXP)
fenvalerate  (ISO)
ferric oxide  (EXP,ISO)
ferrosoferric oxide  (ISO)
ferrostatin-1  (EXP,ISO)
ferrous oxide  (ISO)
ferulic acid  (ISO)
finasteride  (ISO)
fipronil  (ISO)
fisetin  (EXP,ISO)
flavanone  (ISO)
flavanones  (ISO)
flavokawain B  (EXP)
flavones  (ISO)
flavonoids  (EXP,ISO)
fluazinam  (ISO)
flumethrin  (ISO)
fluoranthene  (ISO)
fluoxetine  (EXP,ISO)
flutamide  (EXP,ISO)
flutriafol  (ISO)
fluvastatin  (ISO)
folic acid  (EXP,ISO)
folpet  (ISO)
fomepizole  (EXP)
formaldehyde  (ISO)
formononetin  (ISO)
Forsythiaside  (EXP)
fraxetin  (ISO)
fructose  (EXP,ISO)
fulvestrant  (ISO)
fumonisin B1  (EXP,ISO)
furan  (EXP,ISO)
furosemide  (ISO)
Fusarenone X  (EXP)
galactose  (ISO)
galangin  (ISO)
galanthamine  (ISO)
galanthamine Trifluoroacetic acid  (ISO)
Galbanic acid  (ISO)
gallein  (ISO)
gallic acid  (ISO)
gallium nitrate  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gamma-tocopherol  (ISO)
Ganoderic acid A  (EXP)
Gastrodin  (EXP,ISO)
gefitinib  (ISO)
gemcitabine  (ISO)
Genipin  (ISO)
Geniposide  (ISO)
genistein  (EXP,ISO)
gentamycin  (EXP,ISO)
Gentiopicrin  (EXP,ISO)
geraniol  (EXP,ISO)
geranyl acetate  (ISO)
gingerol  (EXP,ISO)
ginkgetin  (EXP,ISO)
Ginkgoic acid  (ISO)
Ginkgolide C  (ISO)
ginsenoside Rd  (ISO)
ginsenoside Re  (EXP,ISO)
ginsenoside Rg1  (EXP,ISO)
ginsenoside Rg2  (ISO)
glabridin  (EXP,ISO)
glucaric acid  (EXP)
glucose  (EXP,ISO)
glutathione  (EXP,ISO)
glyburide  (ISO)
glycerol  (ISO)
glycine betaine  (ISO)
glycoursodeoxycholic acid  (ISO)
glycyrrhetinate  (ISO)
glycyrrhetinic acid  (ISO)
glycyrrhizinic acid  (ISO)
glyoxylic acid  (EXP)
glyphosate  (EXP,ISO)
gold atom  (ISO)
gold(0)  (ISO)
gossypol  (EXP,ISO)
graphene oxide  (ISO)
graphite  (ISO)
Grifolin  (ISO)
GSK2656157  (ISO)
GW 6471  (EXP)
Gyrophoric acid  (ISO)
haloperidol  (ISO)
halothane  (EXP)
hellebrigenin  (ISO)
hemin  (ISO)
heparin  (ISO)
herbacetin  (ISO)
hesperetin  (EXP,ISO)
hesperidin  (EXP,ISO)
hexadecanoic acid  (EXP,ISO)
hexaflumuron  (ISO)
hexane  (ISO)
hinokiflavone  (EXP)
histamine  (ISO)
homocysteine  (ISO)
Honokiol  (ISO)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (EXP,ISO)
hydroxamic acid  (ISO)
hydroxychloroquine  (ISO)
hydroxytyrosol  (ISO)
hydroxyurea  (EXP,ISO)
hymexazol  (ISO)
hyperforin  (ISO)
hypoxanthine  (ISO)
icariin  (ISO)
icariside II  (ISO)
ICI 118551  (ISO)
idarubicin  (EXP)
idelalisib  (ISO)
ifosfamide  (ISO)
Ile(5)-angiotensin II  (ISO)
imidacloprid  (ISO)
Imipenem-cilastatin  (ISO)
indirubin  (ISO)
indirubin-3'-monoxime  (ISO)
indocyanine green  (ISO)
indole-3-methanol  (EXP,ISO)
indometacin  (ISO)
inositol  (EXP,ISO)
Inotodiol  (ISO)
iodoacetic acid  (EXP)
iohexol  (ISO)
iopamidol  (ISO)
Ioversol  (ISO)
irbesartan  (EXP,ISO)
irinotecan  (ISO)
iron atom  (EXP,ISO)
iron dextran  (EXP,ISO)
iron(0)  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (ISO)
iron(III) nitrilotriacetate  (ISO)
isocarbophos  (ISO)
isoflavones  (ISO)
isoflurane  (EXP,ISO)
isoliquiritigenin  (EXP)
isoniazide  (EXP,ISO)
isopimaric acid  (EXP)
isoprenaline  (EXP,ISO)
isotretinoin  (EXP,ISO)
ivermectin  (ISO)
jaceosidin  (ISO)
JBIR-99  (ISO)
juglone  (ISO)
Jujuboside A  (EXP,ISO)
kaempferol  (EXP,ISO)
kahweol  (ISO)
kainic acid  (EXP,ISO)
ketamine  (ISO)
keto-D-fructose 1,6-bisphosphate  (ISO)
ketoconazole  (ISO)
KN-93  (EXP)
Kukoamine B  (ISO)
L-ascorbic acid  (EXP,ISO)
L-cystathionine  (ISO)
L-gamma-glutamyl-L-cysteine  (ISO)
L-glutamic acid  (ISO)
L-methionine  (EXP,ISO)
L-serine  (ISO)
lactucin  (ISO)
lapatinib  (ISO)
lead diacetate  (ISO)
lead nitrate  (EXP,ISO)
lead(0)  (EXP,ISO)
Leonurine  (EXP,ISO)
leptomycin B  (ISO)
letrozole  (ISO)
leukotriene B4  (ISO)
leupeptin  (ISO)
leuprolide  (ISO)
Licochalcone A  (ISO)
Licochalcone B  (ISO)
lidocaine  (EXP,ISO)
lignan  (ISO)
linalool  (ISO)
linsidomine  (EXP,ISO)
linuron  (ISO)
lipoic acid  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
lipoxin A4  (ISO)
liraglutide  (ISO)
lithium atom  (ISO)
lithium chloride  (EXP,ISO)
lithium hydride  (ISO)
lithocholic acid  (EXP,ISO)
Longikaurin A  (ISO)
lonidamine  (ISO)
losartan  (ISO)
lovastatin  (EXP,ISO)
lupeol  (ISO)
Lupiwighteone  (ISO)
lupulone  (ISO)
lutein  (ISO)
luteolin  (EXP,ISO)
Luteolin 7-methyl ether  (ISO)
luteolin 7-O-beta-D-glucoside  (ISO)
LY294002  (EXP,ISO)
lycopene  (EXP,ISO)
maculosin  (EXP)
madecassoside  (EXP,ISO)
magnesium dichloride  (EXP,ISO)
magnesium oxide  (ISO)
Magnolol  (EXP)
malathion  (EXP,ISO)
malvidin  (ISO)
mancozeb  (EXP,ISO)
maneb  (EXP,ISO)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP,ISO)
mangiferin  (EXP,ISO)
masoprocol  (ISO)
mebendazole  (ISO)
mechlorethamine  (ISO)
medroxyprogesterone acetate  (ISO)
mefenamic acid  (ISO)
meglumine amidotrizoate  (ISO)
MeIQx  (ISO)
melamine  (EXP,ISO)
melatonin  (EXP,ISO)
melittin  (EXP,ISO)
meloxicam  (ISO)
melphalan  (ISO)
memantine  (ISO)
menadione  (ISO)
mercaptopurine  (EXP)
mercury atom  (ISO)
mercury dichloride  (EXP,ISO)
mercury(0)  (ISO)
mesalamine  (ISO)
metaproterenol  (EXP)
metformin  (EXP,ISO)
methadone  (ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (ISO)
methomyl  (EXP)
methotrexate  (EXP,ISO)
methoxsalen  (ISO)
methoxyacetic acid  (ISO)
methoxychlor  (EXP,ISO)
methyl caffeate  (ISO)
methyl methanesulfonate  (ISO)
methylene blue  (ISO)
methylglyoxal  (ISO)
methylisothiazolinone  (ISO)
methyllycaconitine  (ISO)
methylmercury chloride  (EXP,ISO)
methylparaben  (ISO)
methylphenidate  (ISO)
methylseleninic acid  (ISO)
methyltestosterone  (ISO)
metiram  (ISO)
metrafenone  (ISO)
mevinphos  (ISO)
microcystin  (ISO)
microcystin RR  (EXP)
microcystin-LR  (EXP,ISO)
mifepristone  (ISO)
minocycline  (EXP,ISO)
mirtazapine  (EXP)
misoprostol  (ISO)
mitomycin C  (ISO)
Mitoquinone  (EXP)
Mitotane  (ISO)
MitoTEMPO  (EXP,ISO)
mitoxantrone  (ISO)
MK-2206  (ISO)
ML-7  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
monobenzyl phthalate  (EXP,ISO)
Monobutylphthalate  (ISO)
monocrotaline  (EXP,ISO)
monocrotophos  (ISO)
monoethyl phthalate  (EXP,ISO)
monosodium L-glutamate  (EXP,ISO)
montelukast  (EXP)
morin  (ISO)
Morindone  (ISO)
morphine  (EXP,ISO)
Morroniside  (EXP,ISO)
morusin  (ISO)
Muconic dialdehyde  (ISO)
mycophenolic acid  (ISO)
myricetin  (ISO)
myricitrin  (ISO)
myristicin  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N,N-dimethylformamide  (ISO)
N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide  (ISO)
N-(6-acetamidohexyl)acetamide  (ISO)
N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-acetylsphingosine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
N-ethyl-N-nitrosourea  (EXP,ISO)
N-formyl-L-methionyl-L-leucyl-L-phenylalanine  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-D-aspartic acid  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP,ISO)
N-methyl-N-nitrosourea  (ISO)
N-methylnicotinate  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (ISO)
N-phosphocreatine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
naloxone  (ISO)
naphthalene  (ISO)
naringin  (EXP,ISO)
navitoclax  (ISO)
Neferine  (ISO)
neoastilbin  (ISO)
neocuproine  (ISO)
Neoisoliquiritin  (EXP)
neomycin  (EXP)
nerolidol  (ISO)
nickel atom  (ISO)
nickel dichloride  (EXP,ISO)
nickel ferrite  (ISO)
nickel sulfate  (EXP,ISO)
niclosamide  (ISO)
nicorandil  (EXP,ISO)
nicotinamide  (EXP,ISO)
nicotine  (EXP,ISO)
nifedipine  (EXP,ISO)
Niflumic acid  (ISO)
nigericin  (EXP)
nilotinib  (EXP,ISO)
nimesulide  (ISO)
nimodipine  (ISO)
nitenpyram  (ISO)
Nitidine  (ISO)
nitrates  (EXP)
nitrendipine  (ISO)
nitric oxide  (EXP,ISO)
nitrofen  (ISO)
nitrogen dioxide  (EXP,ISO)
nitroprusside  (EXP,ISO)
Nivalenol  (EXP)
NMS-873  (ISO)
nobiletin  (ISO)
nocodazole  (ISO)
Nonylphenol  (EXP,ISO)
Norbinaltorphimine  (EXP)
NORCANTHARIDIN  (ISO)
norfloxacin  (ISO)
norwogonin  (ISO)
notoginsenoside R1  (EXP,ISO)
NS-398  (ISO)
Nutlin-3  (EXP,ISO)
o-cresol  (ISO)
O-methyleugenol  (ISO)
Obacunone  (ISO)
ochratoxin A  (EXP,ISO)
Octicizer  (ISO)
octreotide  (ISO)
octyl gallate  (EXP)
okadaic acid  (EXP,ISO)
olanzapine  (ISO)
olaparib  (ISO)
oleanolic acid  (ISO)
oleic acid  (ISO)
olesoxime  (ISO)
oleuropein  (EXP,ISO)
oligopeptide  (ISO)
olmesartan  (EXP)
Olmesartan medoxomil  (ISO)
oltipraz  (EXP,ISO)
omacetaxine mepesuccinate  (ISO)
omeprazole  (ISO)
Ophiopogonin D  (ISO)
orciprenaline  (EXP)
organoselenium compound  (ISO)
oridonin  (ISO)
orlistat  (ISO)
ortho-Aminoazotoluene  (EXP)
osthole  (ISO)
ouabain  (ISO)
oxalic acid  (ISO)
oxaliplatin  (EXP,ISO)
oxidopamine  (ISO)
oxybenzone  (ISO)
oxybuprocaine  (ISO)
ozone  (ISO)
p-menthan-3-ol  (ISO)
paclitaxel  (EXP,ISO)
paeoniflorin  (EXP,ISO)
Paeonol  (EXP)
palmatine  (EXP)
Palmitic acid(d3)  (ISO)
Panaxynol  (ISO)
Panduratin A  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraoxon  (EXP,ISO)
paraquat  (EXP,ISO)
parathion-methyl  (ISO)
Parthenin  (ISO)
parthenolide  (ISO)
patulin  (EXP)
pefloxacin  (ISO)
penconazole  (ISO)
pendimethalin  (ISO)
Pendulone  (ISO)
pentane  (ISO)
Pentoxifylline  (ISO)
perfluorodecanoic acid  (EXP)
perfluoroheptanoic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
perfluoroundecanoic acid  (ISO)
pergolide  (EXP,ISO)
perifosine  (ISO)
perillyl alcohol  (EXP)
permethrin  (ISO)
peroxynitrous acid  (ISO)
pexidartinib  (EXP)
PF-3758309  (ISO)
phenanthrene  (ISO)
phenethyl caffeate  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP,ISO)
phenylephrine  (ISO)
phenylhydrazine  (EXP)
phenylmercury acetate  (ISO)
phenytoin  (EXP)
PhIP  (EXP,ISO)
phloretin  (ISO)
phloroglucinol  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosphatidylcholine  (ISO)
phosphoramide mustard  (ISO)
physcion  (ISO)
phytol  (EXP)
phytosphingosine  (ISO)
piclamilast  (ISO)
picolinic acid  (ISO)
pifithrin-alpha hydrobromide  (EXP,ISO)
pinostrobin  (ISO)
pioglitazone  (ISO)
piperazine  (ISO)
piperine  (ISO)
piperonyl butoxide  (ISO)
Pirarubicin  (EXP)
pirinixic acid  (ISO)
PK-11195  (ISO)
platinum  (ISO)
platinum(0)  (ISO)
platycodin D  (ISO)
poly(I:C)  (ISO)
Polygodial  (ISO)
polysulfur  (ISO)
ponatinib  (EXP)
Ponicidin  (ISO)
porphyrins  (ISO)
potassium bromate  (ISO)
potassium dichromate  (EXP,ISO)
potassium iodide  (ISO)
Pramanicin  (ISO)
Pranoprofen  (ISO)
pravastatin  (EXP)
prednisone  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
proanthocyanidin  (ISO)
probenecid  (EXP)
probucol  (ISO)
prochloraz  (ISO)
procyanidin  (EXP)
procyanidin B2  (EXP,ISO)
procymidone  (EXP,ISO)
prodigiosin  (ISO)
progesterone  (EXP,ISO)
propacetamol  (EXP)
propiconazole  (ISO)
propionic acid  (ISO)
propofol  (EXP,ISO)
propranolol  (EXP,ISO)
propylparaben  (EXP,ISO)
prostaglandin E2  (ISO)
Protolichesterinic acid  (ISO)
psoralen  (EXP,ISO)
pterostilbene  (EXP,ISO)
puerarin  (ISO)
punicalagin  (ISO)
purine-6-thiol  (EXP)
purmorphamine  (ISO)
puromycin  (ISO)
pyrene  (ISO)
pyrethrins  (ISO)
Pyridostigmine bromide  (ISO)
pyridoxine  (ISO)
pyrroles  (ISO)
pyrrolidine dithiocarbamate  (ISO)
pyrroloquinoline quinone  (EXP,ISO)
quartz  (ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-galactopyranoside  (ISO)
quercetin 4'-O-beta-D-glucopyranoside  (ISO)
quercitrin  (ISO)
quetiapine fumarate  (ISO)
quinacrine  (ISO)
quinazolines  (ISO)
quinolinic acid  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
ramipril  (ISO)
ranitidine  (ISO)
razoxane  (EXP)
reactive oxygen species  (EXP,ISO)
Rebamipide  (ISO)
rebaudioside A  (ISO)
remdesivir  (ISO)
reserpine  (ISO)
resolvin D1  (ISO)
resveratrol  (EXP,ISO)
Rhein  (ISO)
riboflavin  (ISO)
rifampicin  (EXP,ISO)
rimonabant  (EXP,ISO)
rivastigmine  (ISO)
Ro 31-8220  (ISO)
rocaglamide  (ISO)
roflumilast  (ISO)
rolipram  (ISO)
Roridin A  (EXP)
rosmarinic acid  (EXP)
rosuvastatin calcium  (ISO)
rotenone  (EXP,ISO)
rottlerin  (EXP,ISO)
royal jelly  (ISO)
rubitecan  (ISO)
ruthenium atom  (ISO)
ruthenium red  (EXP)
rutin  (EXP,ISO)
ruxolitinib  (EXP,ISO)
ryanodine  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
S-nitroso-N-acetyl-D-penicillamine  (EXP)
S-nitrosoglutathione  (ISO)
saccharin  (ISO)
safrole  (ISO)
Salidroside  (EXP,ISO)
Salinomycin  (ISO)
salubrinal  (EXP,ISO)
Salvianolic acid A  (ISO)
salvianolic acid B  (EXP,ISO)
Sanggenon C  (ISO)
sanguinarine  (ISO)
sappanchalcone  (ISO)
sarin  (ISO)
sarpogrelate  (EXP,ISO)
SB 203580  (EXP,ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
scoparone  (ISO)
scopolamine  (EXP,ISO)
scopoletin  (ISO)
scutellarin  (EXP)
selenium atom  (EXP,ISO)
selenocystine  (ISO)
semilicoisoflavone B  (ISO)
serpentine asbestos  (ISO)
Sesamol  (EXP)
sesquiterpene  (ISO)
sevoflurane  (EXP,ISO)
Shikonin  (ISO)
sibutramine  (ISO)
sildenafil citrate  (ISO)
silibinin  (ISO)
silicon dioxide  (EXP,ISO)
silmitasertib  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP,ISO)
sinapic acid  (ISO)
sirolimus  (EXP,ISO)
sirtinol  (EXP,ISO)
SNX-2112  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium azide  (ISO)
sodium chloride  (ISO)
sodium cholate  (EXP)
sodium chromate  (EXP,ISO)
sodium dichromate  (ISO)
sodium disulfite  (ISO)
sodium fluoride  (EXP,ISO)
sodium nitrite  (ISO)
sodium propionate  (EXP)
Soman  (EXP,ISO)
Sophoricoside  (EXP)
sorafenib  (EXP,ISO)
spermine  (EXP)
sphingosine 1-phosphate  (ISO)
Spiroquinazoline  (ISO)
squalene  (ISO)
staurosporine  (EXP,ISO)
sterigmatocystin  (ISO)
steviol  (ISO)
stevioside  (ISO)
stilbenoid  (ISO)
streptozocin  (EXP,ISO)
styrene  (ISO)
styrene oxide  (ISO)
succimer  (ISO)
succinic acid  (ISO)
sulfaphenazole  (ISO)
sulfasalazine  (ISO)
sulforaphane  (EXP,ISO)
sulfur atom  (ISO)
sulfur dioxide  (EXP)
sulindac  (ISO)
sulindac sulfide  (EXP,ISO)
sulpiride  (EXP)
surfactin  (ISO)
surfactin C  (ISO)
Swertiamarin  (ISO)
syringic acid  (ISO)
syringin  (ISO)
T-2 toxin  (EXP,ISO)
tacrine  (EXP,ISO)
tacrolimus hydrate  (EXP,ISO)
tadalafil  (ISO)
talazoparib  (ISO)
tamoxifen  (EXP,ISO)
Tanshinone I  (ISO)
Tariquidar  (EXP)
taurine  (ISO)
tauroursodeoxycholic acid  (EXP,ISO)
tazarotene  (ISO)
tebuconazole  (ISO)
telmisartan  (ISO)
temozolomide  (EXP,ISO)
terazosin  (ISO)
Terfenadine  (ISO)
tert-butyl hydroperoxide  (EXP,ISO)
testosterone  (EXP,ISO)
testosterone enanthate  (ISO)
tetrachloroethene  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
tetrahydropalmatine  (ISO)
tetramethylpyrazine  (ISO)
tetraphene  (EXP)
tetrathiomolybdate(2-)  (ISO)
thalidomide  (ISO)
thapsigargin  (ISO)
Theaflavin 3,3'-digallate  (ISO)
thiamethoxam  (EXP)
thiamine(1+) chloride  (EXP,ISO)
thimerosal  (ISO)
thioacetamide  (EXP,ISO)
thiostrepton  (ISO)
Thiotepa  (ISO)
thiourea  (ISO)
thymidine  (ISO)
thymol  (ISO)
thymol sulfate(1-)  (ISO)
thymoquinone  (EXP,ISO)
Tiron  (ISO)
titanium dioxide  (EXP,ISO)
tocopherol  (ISO)
tomelukast  (ISO)
Tomentosin  (ISO)
toosendanin  (ISO)
topotecan  (ISO)
tramadol  (ISO)
trametinib  (EXP)
tranexamic acid  (ISO)
trans-anethole  (ISO)
trans-cinnamic acid  (ISO)
tranylcypromine  (ISO)
triadimefon  (ISO)
triamcinolone acetonide  (ISO)
triazoles  (ISO)
tributylstannane  (EXP,ISO)
Tributyltin oxide  (EXP)
tricetin  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triciribine  (ISO)
triclosan  (EXP,ISO)
trifluoperazine  (ISO)
trilobatin  (ISO)
trimethylamine N-oxide  (ISO)
trimethyltin  (EXP)
triphenyl phosphate  (EXP,ISO)
Triptolide  (EXP,ISO)
tris(picolinato)chromium  (ISO)
troglitazone  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
tropisetron  (ISO)
Tubeimoside I  (ISO)
tungsten  (EXP)
Tungsten carbide  (ISO)
tunicamycin  (ISO)
tyrphostin AG 1478  (EXP,ISO)
umbelliferone  (ISO)
urethane  (EXP)
uridine  (ISO)
ursodeoxycholic acid  (EXP,ISO)
ursolic acid  (EXP,ISO)
usnic acid  (ISO)
valproic acid  (EXP,ISO)
valsartan  (EXP,ISO)
vanadyl sulfate  (ISO)
vancomycin  (ISO)
veliparib  (ISO)
vemurafenib  (ISO)
venetoclax  (ISO)
venlafaxine hydrochloride  (ISO)
venom  (ISO)
verapamil  (ISO)
Vernodalin  (ISO)
verteporfin  (ISO)
Vicanicin  (ISO)
vildagliptin  (ISO)
vinclozolin  (ISO)
vincristine  (EXP,ISO)
vindesine  (ISO)
Vinpocetine  (ISO)
vitamin D  (ISO)
vitamin E  (ISO)
vitexin  (EXP)
vorinostat  (EXP,ISO)
VX nerve agent  (ISO)
wedelolactone  (EXP)
withaferin A  (ISO)
wogonin  (ISO)
wortmannin  (ISO)
xanthohumol  (ISO)
Xanthorrhizol  (ISO)
XAV939  (ISO)
XMU-MP-1  (ISO)
Y-27632  (ISO)
ytterbium  (ISO)
yttrium chloride  (ISO)
zearalenone  (EXP,ISO)
zebularine  (ISO)
zerumbone  (ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (EXP,ISO)
zinc molecular entity  (ISO)
zinc oxide  (EXP,ISO)
zinc protoporphyrin  (EXP,ISO)
zinc pyrithione  (ISO)
zinc sulfate  (ISO)
zinc(0)  (EXP,ISO)
zingerone  (ISO)
zingiberene  (ISO)
ziram  (ISO)
zoledronic acid  (EXP,ISO)
zolmitriptan  (ISO)
zoxamide  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic mitochondrial changes  (IDA,ISO)
apoptotic process  (IDA,IGI,IMP,ISO)
apoptotic process involved in blood vessel morphogenesis  (IGI)
apoptotic process involved in embryonic digit morphogenesis  (IGI)
apoptotic process involved in mammary gland involution  (IMP)
apoptotic signaling pathway  (IGI,IMP,ISO)
B cell apoptotic process  (IGI,ISO)
B cell homeostasis  (IGI,IMP)
B cell homeostatic proliferation  (IMP)
B cell negative selection  (IGI)
B cell receptor apoptotic signaling pathway  (IEA,ISO)
blood vessel remodeling  (IGI)
calcium ion transport into cytosol  (IGI)
cell population proliferation  (IGI)
cellular respiration  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to UV  (IGI)
cellular response to virus  (IEA,ISO)
cerebral cortex development  (IMP,ISO)
development of secondary sexual characteristics  (IMP)
DNA damage response  (IMP)
ectopic germ cell programmed cell death  (IGI,IMP)
epithelial cell apoptotic process  (IMP)
epithelial cell proliferation  (IDA)
establishment of localization in cell  (IGI,IMP)
establishment or maintenance of transmembrane electrochemical gradient  (ISO,ISS)
execution phase of apoptosis  (IEA,ISO)
extrinsic apoptotic signaling pathway  (ISO)
extrinsic apoptotic signaling pathway in absence of ligand  (IBA,IGI)
extrinsic apoptotic signaling pathway via death domain receptors  (IDA)
fertilization  (IGI)
germ cell development  (IGI)
glial cell apoptotic process  (ISO)
glycosphingolipid metabolic process  (IMP)
homeostasis of number of cells  (IGI,IMP)
homeostasis of number of cells within a tissue  (IMP)
hypothalamus development  (IMP)
inner mitochondrial membrane organization  (ISO)
intrinsic apoptotic signaling pathway  (IMP,ISO)
intrinsic apoptotic signaling pathway by p53 class mediator  (IMP)
intrinsic apoptotic signaling pathway in response to DNA damage  (IBA,IGI,IMP,ISO)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  (IGI,ISO)
kidney development  (IGI)
leukocyte homeostasis  (IGI)
limb morphogenesis  (IGI)
male gonad development  (IGI,IMP)
mitochondrial fragmentation involved in apoptotic process  (ISO,ISS)
mitochondrial fusion  (IBA,IGI,ISO,ISS)
mitochondrion organization  (IGI)
motor neuron apoptotic process  (IMP)
myeloid cell homeostasis  (IGI)
negative regulation of apoptotic signaling pathway  (IGI)
negative regulation of cell population proliferation  (IMP)
negative regulation of endoplasmic reticulum calcium ion concentration  (IGI)
negative regulation of fibroblast proliferation  (IMP)
negative regulation of mitochondrial membrane potential  (ISO,ISS)
negative regulation of neuron apoptotic process  (IDA)
negative regulation of peptidyl-serine phosphorylation  (IGI)
nervous system development  (IMP)
neuron apoptotic process  (IDA,IGI,IMP)
neuron migration  (IMP)
odontogenesis of dentin-containing tooth  (IGI)
outer mitochondrial membrane organization  (ISO)
ovarian follicle development  (IGI,IMP,ISO)
peptidyl-serine phosphorylation  (IGI)
positive regulation of apoptotic DNA fragmentation  (IEA,ISO)
positive regulation of apoptotic process  (IDA,IGI,IMP,ISO)
positive regulation of apoptotic process involved in mammary gland involution  (IMP)
positive regulation of B cell apoptotic process  (IGI)
positive regulation of calcium ion transport into cytosol  (IGI)
positive regulation of developmental pigmentation  (IGI)
positive regulation of developmental process  (IMP)
positive regulation of endoplasmic reticulum unfolded protein response  (ISO)
positive regulation of epithelial cell apoptotic process  (IMP)
positive regulation of intrinsic apoptotic signaling pathway  (IMP,ISO,ISS)
positive regulation of mitochondrial membrane permeability involved in apoptotic process  (IGI)
positive regulation of motor neuron apoptotic process  (IMP)
positive regulation of neuron apoptotic process  (IBA,IGI,IMP,ISO)
positive regulation of protein-containing complex assembly  (ISO,ISS)
positive regulation of release of cytochrome c from mitochondria  (ISO,ISS)
positive regulation of release of sequestered calcium ion into cytosol  (IMP)
positive regulation of reproductive process  (IMP)
post-embryonic camera-type eye morphogenesis  (IGI)
post-embryonic development  (IGI)
protein insertion into mitochondrial membrane  (IMP)
regulation of apoptotic process  (IMP,ISO)
regulation of cell cycle  (IGI)
regulation of mammary gland epithelial cell proliferation  (IMP)
regulation of mitochondrial membrane permeability involved in apoptotic process  (IGI)
regulation of mitochondrial membrane permeability involved in programmed necrotic cell death  (IMP)
regulation of mitochondrial membrane potential  (IDA,ISO)
regulation of neuron apoptotic process  (IMP,ISO)
regulation of nitrogen utilization  (IGI)
release of cytochrome c from mitochondria  (IBA,IDA,IGI,ISO)
release of matrix enzymes from mitochondria  (ISO,ISS)
release of sequestered calcium ion into cytosol  (IMP)
response to anesthetic  (ISO)
response to axon injury  (IMP)
response to cocaine  (ISO)
response to copper ion  (ISO)
response to corticosterone  (ISO)
response to gamma radiation  (IMP)
response to hypoxia  (ISO)
response to insulin-like growth factor stimulus  (ISO)
response to ionizing radiation  (IGI,IMP)
response to ischemia  (ISO)
response to salt stress  (IGI)
response to toxic substance  (IMP,ISO)
response to wounding  (IMP)
response to xenobiotic stimulus  (ISO)
retina development in camera-type eye  (IMP)
retinal cell programmed cell death  (IMP)
Sertoli cell proliferation  (IGI)
sex differentiation  (IMP)
spermatid differentiation  (IMP)
spermatogenesis  (IGI,IMP)
supramolecular fiber organization  (IEA,ISO)
swimming behavior  (ISO)
T cell homeostatic proliferation  (IMP)
thymocyte apoptotic process  (IGI)
vagina development  (IGI)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal axon extension  (IAGP)
abnormal B cell morphology  (IAGP)
abnormal B cell number  (IAGP)
abnormal B cell physiology  (IAGP)
abnormal brain morphology  (IAGP)
abnormal cerebellar granule layer morphology  (IAGP)
abnormal cerebellar Purkinje cell layer  (IAGP)
abnormal definitive hematopoiesis  (IAGP)
abnormal dorsal root ganglion morphology  (IAGP)
abnormal enteric neuron morphology  (IAGP)
abnormal facial motor nucleus morphology  (IAGP)
abnormal gametogenesis  (IAGP)
abnormal hearing physiology  (IAGP)
abnormal innervation  (IAGP)
abnormal lung development  (IAGP)
abnormal male germ cell apoptosis  (IAGP)
abnormal mitochondrial morphology  (IAGP)
abnormal motor neuron innervation pattern  (IAGP)
abnormal motor neuron morphology  (IAGP)
abnormal neuron morphology  (IAGP)
abnormal oogenesis  (IAGP)
abnormal ovarian folliculogenesis  (IAGP)
abnormal phrenic nerve innervation pattern to diaphragm  (IAGP)
abnormal phrenic nerve morphology  (IAGP)
abnormal postnatal growth/weight/body size  (IAGP)
abnormal primordial germ cell migration  (IAGP)
abnormal primordial germ cell morphology  (IAGP)
abnormal primordial germ cell proliferation  (IAGP)
abnormal proprioceptive neuron morphology  (IAGP)
abnormal Purkinje cell dendrite morphology  (IAGP)
abnormal Purkinje cell morphology  (IAGP)
abnormal seminiferous tubule epithelium morphology  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal sensory neuron innervation pattern  (IAGP)
abnormal skeletal muscle fiber morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal splenocyte physiology  (IAGP)
abnormal superior cervical ganglion morphology  (IAGP)
abnormal sympathetic neuron morphology  (IAGP)
abnormal T cell differentiation  (IAGP)
abnormal T cell morphology  (IAGP)
abnormal voluntary movement  (IAGP)
absent muscle spindles  (IAGP)
anemia  (IAGP)
arrest of male meiosis  (IAGP)
arrest of spermatogenesis  (IAGP)
ataxia  (IAGP)
autoimmune arthritis  (IAGP)
azoospermia  (IAGP)
circling  (IAGP)
decreased apoptosis  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased cellular sensitivity to gamma-irradiation  (IAGP)
decreased cerebellar granule cell number  (IAGP)
decreased male germ cell number  (IAGP)
decreased marginal zone B cell number  (IAGP)
decreased motor neuron number  (IAGP)
decreased neuron apoptosis  (IAGP)
decreased physiological sensitivity to xenobiotic  (IAGP)
decreased primordial germ cell number  (IAGP)
decreased Purkinje cell number  (IAGP)
decreased striatum size  (IAGP)
decreased testis weight  (IAGP)
decreased thymocyte apoptosis  (IAGP)
decreased thymocyte number  (IAGP)
enlarged lymph nodes  (IAGP)
enlarged spleen  (IAGP)
extended life span  (IAGP)
gliosis  (IAGP)
glomerulonephritis  (IAGP)
impaired coordination  (IAGP)
impaired skeletal muscle regeneration  (IAGP)
increased adenocarcinoma incidence  (IAGP)
increased anti-double stranded DNA antibody level  (IAGP)
increased atretic ovarian follicle number  (IAGP)
increased B cell number  (IAGP)
increased B-2 B cell number  (IAGP)
increased bone marrow cell number  (IAGP)
increased brain size  (IAGP)
increased follicular B cell number  (IAGP)
increased IgA level  (IAGP)
increased IgG level  (IAGP)
increased IgM level  (IAGP)
increased immunoglobulin level  (IAGP)
increased leukocyte cell number  (IAGP)
increased lymphocyte cell number  (IAGP)
increased male germ cell apoptosis  (IAGP)
increased mature ovarian follicle number  (IAGP)
increased motor neuron number  (IAGP)
increased muscle spindle number  (IAGP)
increased neuron number  (IAGP)
increased pre-B cell number  (IAGP)
increased pro-B cell number  (IAGP)
increased regulatory T cell number  (IAGP)
increased sensory neuron number  (IAGP)
increased skeletal muscle mass  (IAGP)
increased spleen red pulp amount  (IAGP)
increased spleen white pulp amount  (IAGP)
increased susceptibility to autoimmune disorder  (IAGP)
increased thymocyte number  (IAGP)
increased transitional stage B cell number  (IAGP)
interdigital webbing  (IAGP)
male infertility  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
reduced cerebellar foliation  (IAGP)
seizures  (IAGP)
small seminiferous tubules  (IAGP)
small thymus  (IAGP)
thrombocytopenia  (IAGP)
uterus hypertrophy  (IAGP)
vagina atresia  (IAGP)
weakness  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. The Bcl-2 apoptotic switch in cancer development and therapy. Adams JM and Cory S, Oncogene. 2007 Feb 26;26(9):1324-37.
2. Bax mutation and overexpression inversely correlate with immature phenotype and prognosis of childhood germ cell tumors. Addeo R, etal., Oncol Rep. 2007 May;17(5):1155-61.
3. Lung injury after ischemia-reperfusion of small intestine in rats involves apoptosis of type II alveolar epithelial cells mediated by TNF-alpha and activation of Bid pathway. An S, etal., Apoptosis. 2007 Nov;12(11):1989-2001. doi: 10.1007/s10495-007-0125-1.
4. Neutrophil gelatinase-associated lipocalin (NGAL) may play a protective role against rats ischemia/reperfusion renal injury via inhibiting tubular epithelial cell apoptosis. An S, etal., Ren Fail. 2013;35(1):143-9. doi: 10.3109/0886022X.2012.741877. Epub 2012 Nov 15.
5. Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes. Ares-Carrasco S, etal., Am J Physiol Heart Circ Physiol. 2009 Oct 9.
6. Elevated caspase and AIF gene expression correlate with progression of sarcopenia during aging in male F344BN rats. Baker DJ and Hepple RT, Exp Gerontol. 2006 Nov;41(11):1149-56. Epub 2006 Oct 6.
7. Cardioprotective role of growth/differentiation factor 1 in post-infarction left ventricular remodelling and dysfunction. Bao MW, etal., J Pathol. 2015 Jul;236(3):360-72. doi: 10.1002/path.4523. Epub 2015 Mar 30.
8. Bax and Bid act in synergy to bring about T11TS-mediated glioma apoptosis via the release of mitochondrial cytochrome c and subsequent caspase activation. Bhattacharjee M, etal., Int Immunol. 2008 Dec;20(12):1489-505. Epub 2008 Oct 17.
9. T11TS Treatment Augments Apoptosis of Glioma Associated Brain Endothelial Cells, Hint Toward Anti-Angiogenic Action in Glioma. Bhattacharya D, etal., J Cell Physiol. 2017 Mar;232(3):526-539. doi: 10.1002/jcp.25447. Epub 2016 Jun 21.
10. Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer. Bishayee A, etal., Int J Cancer. 2013 Sep 1;133(5):1054-63. doi: 10.1002/ijc.28108. Epub 2013 Mar 29.
11. ZFP36 protects lungs from intestinal I/R-induced injury and fibrosis through the CREBBP/p53/p21/Bax pathway. Cao Y, etal., Cell Death Dis. 2021 Jul 8;12(7):685. doi: 10.1038/s41419-021-03950-y.
12. Role of p97/Valosin-containing protein (VCP) and Jab1/CSN5 in testicular ischaemia-reperfusion injury. Cayli S, etal., J Mol Histol. 2016 Feb;47(1):91-100. doi: 10.1007/s10735-016-9652-9. Epub 2016 Jan 11.
13. Significance of Bcl-2 and Bax proteins in cervical carcinogenesis: an immunohistochemical study in squamous cell carcinoma and squamous intraepithelial lesions. Cheah PL and Looi LM, Malays J Pathol. 2006 Jun;28(1):1-5.
14. Induction of Bcl-2 and Bax was related to hyperphosphorylation of tau and neuronal death induced by okadaic acid in rat brain. Chen LQ, etal., Anat Rec A Discov Mol Cell Evol Biol. 2005 Dec;287(2):1236-45.
15. Interfering effect and mechanism of neuregulin on experimental dementia model in rats. Chen Y, etal., Behav Brain Res. 2011 Sep 23;222(2):321-5. doi: 10.1016/j.bbr.2011.03.063. Epub 2011 Apr 5.
16. Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease. Chiesa R, etal., Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):238-43. doi: 10.1073/pnas.0406173102. Epub 2004 Dec 23.
17. Peroxisome proliferator-activated receptors gamma/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus. Chuang YC, etal., J Neuroinflammation. 2012 Jul 31;9:184.
18. [Effects of BNP preconditioning on myocardial cell apoptosis and expressions of bcl-2 and Bax during myocardial ischemia-reperfusion injury in rats]. Deng YJ, etal., Zhonghua Yi Xue Za Zhi. 2010 Dec 28;90(48):3431-4.
19. Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods. Dupe V, etal., Dev Biol 1999 Apr 1;208(1):30-43.
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PMID:11086988   PMID:11092819   PMID:11095619   PMID:11108294   PMID:11144029   PMID:11146002   PMID:11146504   PMID:11150333   PMID:11163212   PMID:11179500   PMID:11212265   PMID:11217851  
PMID:11226327   PMID:11259653   PMID:11290297   PMID:11298357   PMID:11301022   PMID:11369777   PMID:11413548   PMID:11431698   PMID:11526197   PMID:11536012   PMID:11567994   PMID:11604501  
PMID:11717344   PMID:11731234   PMID:11731452   PMID:11784036   PMID:11804960   PMID:11810634   PMID:11836241   PMID:11840165   PMID:11842081   PMID:11850816   PMID:11850820   PMID:11864976  
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PMID:17438128   PMID:17443793   PMID:17443816   PMID:17447031   PMID:17447897   PMID:17448907   PMID:17470554   PMID:17476283   PMID:17491656   PMID:17507417   PMID:17519046   PMID:17525161  
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PMID:17822434   PMID:17869640   PMID:17901408   PMID:17967808   PMID:17982095   PMID:17984095   PMID:17989286   PMID:17996028   PMID:18006502   PMID:18006817   PMID:18024075   PMID:18032672  
PMID:18032675   PMID:18037375   PMID:18048346   PMID:18097759   PMID:18158332   PMID:18160647   PMID:18211809   PMID:18230621   PMID:18232736   PMID:18247359   PMID:18251703   PMID:18252892  
PMID:18266059   PMID:18272391   PMID:18274907   PMID:18281459   PMID:18287228   PMID:18287559   PMID:18288109   PMID:18299329   PMID:18307410   PMID:18308723   PMID:18321965   PMID:18323418  
PMID:18337425   PMID:18362350   PMID:18382684   PMID:18385258   PMID:18385316   PMID:18415933   PMID:18419764   PMID:18426910   PMID:18436203   PMID:18437166   PMID:18450962   PMID:18468793  
PMID:18474606   PMID:18498735   PMID:18499746   PMID:18522850   PMID:18538580   PMID:18563702   PMID:18590778   PMID:18614015   PMID:18627254   PMID:18670882   PMID:18678651   PMID:18691924  
PMID:18708175   PMID:18722365   PMID:18765270   PMID:18799693   PMID:18818203   PMID:18818304   PMID:18835564   PMID:18840766   PMID:18940243   PMID:18981230   PMID:19017630   PMID:19020035  
PMID:19029044   PMID:19029045   PMID:19056676   PMID:19059313   PMID:19064728   PMID:19074266   PMID:19079139   PMID:19082896   PMID:19087264   PMID:19091958   PMID:19110998   PMID:19139105  
PMID:19139267   PMID:19139629   PMID:19168892   PMID:19185578   PMID:19228815   PMID:19261612   PMID:19273598   PMID:19300452   PMID:19307306   PMID:19322198   PMID:19332555   PMID:19339988  
PMID:19373582   PMID:19376889   PMID:19387006   PMID:19389346   PMID:19454696   PMID:19502415   PMID:19519627   PMID:19521510   PMID:19538736   PMID:19617898   PMID:19620044   PMID:19621384  
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PMID:20360684   PMID:20360947   PMID:20392943   PMID:20445064   PMID:20457813   PMID:20503275   PMID:20530288   PMID:20534675   PMID:20539308   PMID:20559321   PMID:20601106   PMID:20621101  
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PMID:21115610   PMID:21117150   PMID:21123558   PMID:21127253   PMID:21146511   PMID:21151029   PMID:21151121   PMID:21160028   PMID:21173168   PMID:21219476   PMID:21221781   PMID:21224042  
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PMID:21368834   PMID:21385880   PMID:21414921   PMID:21425311   PMID:21430642   PMID:21434306   PMID:21451108   PMID:21460835   PMID:21494564   PMID:21546903   PMID:21606679   PMID:21609830  
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PMID:21746927   PMID:21765887   PMID:21768356   PMID:21820438   PMID:21855805   PMID:21873635   PMID:21880664   PMID:21896738   PMID:21911424   PMID:21926988   PMID:21953454   PMID:21965333  
PMID:21967036   PMID:21976497   PMID:21997190   PMID:22015606   PMID:22015607   PMID:22028026   PMID:22031758   PMID:22034980   PMID:22036586   PMID:22043283   PMID:22056880   PMID:22103411  
PMID:22117778   PMID:22179045   PMID:22197342   PMID:22212482   PMID:22216013   PMID:22223437   PMID:22227450   PMID:22275881   PMID:22277657   PMID:22279230   PMID:22280356   PMID:22294729  
PMID:22297488   PMID:22302823   PMID:22355072   PMID:22357545   PMID:22365665   PMID:22383494   PMID:22385963   PMID:22389723   PMID:22396220   PMID:22397680   PMID:22403281   PMID:22403441  
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PMID:23175186   PMID:23197294   PMID:23201261   PMID:23223278   PMID:23224557   PMID:23248281   PMID:23340267   PMID:23345450   PMID:23349374   PMID:23374347   PMID:23375500   PMID:23377280  
PMID:23389440   PMID:23395376   PMID:23422829   PMID:23459946   PMID:23466994   PMID:23467373   PMID:23468630   PMID:23475110   PMID:23481305   PMID:23522042   PMID:23558951   PMID:23591430  
PMID:23614607   PMID:23666531   PMID:23677993   PMID:23685130   PMID:23697557   PMID:23713735   PMID:23744079   PMID:23744350   PMID:23767404   PMID:23770239   PMID:23773998   PMID:23784543  
PMID:23788622   PMID:23790753   PMID:23805138   PMID:23840835   PMID:23842495   PMID:23852275   PMID:23858059   PMID:23881917   PMID:23922915   PMID:23991283   PMID:24003036   PMID:24036309  
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PMID:24457600   PMID:24464220   PMID:24493802   PMID:24525733   PMID:24632563   PMID:24637330   PMID:24733831   PMID:24786774   PMID:24806680   PMID:24825107   PMID:24837741   PMID:24876160  
PMID:24901048   PMID:24912196   PMID:24927528   PMID:24966374   PMID:25102060   PMID:25111896   PMID:25124553   PMID:25146925   PMID:25158854   PMID:25169191   PMID:25228770   PMID:25242145  
PMID:25298417   PMID:25301392   PMID:25315775   PMID:25411208   PMID:25417164   PMID:25482068   PMID:25482509   PMID:25497728   PMID:25501893   PMID:25521332   PMID:25525272   PMID:25556649  
PMID:25565426   PMID:25627690   PMID:25632145   PMID:25680506   PMID:25811803   PMID:25815636   PMID:25855178   PMID:25856413   PMID:25862283   PMID:25985365   PMID:26030884   PMID:26031240  
PMID:26059977   PMID:26159699   PMID:26175676   PMID:26179069   PMID:26180237   PMID:26203146   PMID:26224005   PMID:26288377   PMID:26299946   PMID:26334721   PMID:26344567   PMID:26363094  
PMID:26385183   PMID:26418744   PMID:26438731   PMID:26476335   PMID:26585277   PMID:26702098   PMID:26718146   PMID:26785948   PMID:26795252   PMID:26857994   PMID:26938300   PMID:26943318  
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PMID:30593308   PMID:30635284   PMID:30858352   PMID:30905411   PMID:30938680   PMID:30970242   PMID:30970248   PMID:31042147   PMID:31091440   PMID:31178404   PMID:31199666   PMID:31230859  
PMID:31255486   PMID:31296963   PMID:31298394   PMID:31427287   PMID:31433907   PMID:31485651   PMID:31488565   PMID:31515492   PMID:31534164   PMID:31575648   PMID:31581792   PMID:31626642  
PMID:31721194   PMID:31749402   PMID:31754036   PMID:31806625   PMID:31891351   PMID:31901077   PMID:31935927   PMID:31944180   PMID:31976859   PMID:31987956   PMID:32236527   PMID:32377732  
PMID:32414809   PMID:32451402   PMID:32464196   PMID:32471877   PMID:32533918   PMID:32554809   PMID:32578902   PMID:32620813   PMID:32633719   PMID:32686739   PMID:32703236   PMID:32707083  
PMID:32708537   PMID:32776015   PMID:32826903   PMID:32848017   PMID:32914226   PMID:33007882   PMID:33060174   PMID:33208470   PMID:33231170   PMID:33253203   PMID:33290732   PMID:33303681  
PMID:33323382   PMID:33334825   PMID:33434191   PMID:33462220   PMID:33479483   PMID:33512417   PMID:33586242   PMID:33631669   PMID:33712461   PMID:33823136   PMID:33959612   PMID:34079124  
PMID:34098747   PMID:34284777   PMID:34289356   PMID:34321999   PMID:34362433   PMID:34702745   PMID:34725331   PMID:34873168   PMID:34984584   PMID:35139355   PMID:35191484   PMID:35281062  
PMID:35292986   PMID:35361962   PMID:35377412   PMID:35393408   PMID:35396933   PMID:35481836   PMID:35533272   PMID:35593401   PMID:35688289   PMID:35690225   PMID:35700329   PMID:35793629  
PMID:35977544   PMID:36127325   PMID:36253375   PMID:36313771   PMID:36409059   PMID:36527791   PMID:36635771   PMID:36856110   PMID:36934089   PMID:37106422   PMID:37168577   PMID:37470810  
PMID:37480037   PMID:37494420   PMID:37608075   PMID:37686246   PMID:37702066   PMID:37813816   PMID:37910517   PMID:37985759   PMID:38001340   PMID:38025786   PMID:38110222   PMID:38359835  
PMID:38503284   PMID:38529784   PMID:38671004   PMID:39183304   PMID:39271041   PMID:39307450   PMID:39527572  


Genomics

Comparative Map Data
Bax
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,111,124 - 45,116,332 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,111,121 - 45,116,322 (-)EnsemblGRCm39 Ensembl
GRCm38745,461,695 - 45,466,903 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,461,697 - 45,466,898 (-)EnsemblGRCm38mm10GRCm38
MGSCv37752,717,065 - 52,722,268 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,329,744 - 45,334,864 (-)NCBIMGSCv36mm8
Celera740,917,745 - 40,922,946 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.32NCBI
BAX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,954,875 - 48,961,798 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,954,815 - 48,961,798 (+)EnsemblGRCh38hg38GRCh38
GRCh371949,458,132 - 49,465,055 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,149,929 - 54,156,867 (+)NCBINCBI36Build 36hg18NCBI36
Build 341954,149,928 - 54,156,866NCBI
Celera1946,325,480 - 46,332,409 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,835,055 - 45,841,975 (+)NCBIHuRef
CHM1_11949,460,326 - 49,467,266 (+)NCBICHM1_1
T2T-CHM13v2.01951,949,757 - 51,956,683 (+)NCBIT2T-CHM13v2.0
Bax
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,076,472 - 105,081,906 (-)NCBIGRCr8
mRatBN7.2195,940,001 - 95,945,407 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,938,808 - 95,945,368 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,325,431 - 101,330,837 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,798,107 - 109,803,513 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,088,504 - 103,093,910 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,451,801 - 101,457,207 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,451,802 - 101,457,207 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,530,747 - 102,536,153 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,933,023 - 95,938,176 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1196,011,133 - 96,016,287 (-)NCBI
Celera190,195,913 - 90,201,319 (-)NCBICelera
Cytogenetic Map1q22NCBI
Bax
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,695,960 - 1,700,244 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,695,960 - 1,700,246 (-)NCBIChiLan1.0ChiLan1.0
BAX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,059,801 - 55,066,754 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11956,985,941 - 56,992,885 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,955,926 - 45,962,870 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,793,594 - 54,800,466 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,793,594 - 54,800,468 (-)Ensemblpanpan1.1panPan2
BAX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,423,388 - 107,426,464 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,422,424 - 107,426,464 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,945,329 - 106,949,006 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,947,413 - 107,951,165 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,947,430 - 107,951,107 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,614,952 - 107,618,629 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,261,311 - 107,264,988 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,096,913 - 108,100,590 (-)NCBIUU_Cfam_GSD_1.0
Bax
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,349,880 - 21,355,462 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366642,967,865 - 2,973,820 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366642,968,103 - 2,973,652 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BAX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,222,336 - 54,228,147 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,222,341 - 54,228,150 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,100,514 - 50,106,337 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BAX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,186,028 - 42,193,105 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607322,071,985 - 22,079,701 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bax
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,050,222 - 5,055,506 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248325,050,222 - 5,068,565 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bax
236 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:184
Count of miRNA genes:167
Interacting mature miRNAs:176
Transcripts:ENSMUST00000033093
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
38501071Stsl6_mSalmonella typhimurium susceptibility locus 6 (mouse)73419942551149748Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
39128210Lwq19_mliver weight QTL 19 (mouse)73349772758148965Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1357469Kidq5_mkidney weight QTL 5 (mouse)Not determined73349772758148965Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
4142003W3q10_mweight 3 weeks QTL 10 (mouse)Not determined3349772758148965Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse
1559000Ossc1_mosteosarcoma susceptibility 1 (mouse)Not determined73405302568053223Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
1357634Splq7_mspleen weight QTL 7 (mouse)Not determined73349772758148965Mouse
4141929Chlq18_mcirculating hormone level QTL 18 (mouse)Not determined74114882075148965Mouse
1300996Aorls2_maortic lesion size 2 (mouse)Not determined73239453266394681Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1300878Skts1_mskin tumor susceptibility 1 (mouse)Not determined73789138671891582Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301175Ap7q_malcohol preference 7 QTL (mouse)Not determined73171484565715077Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
10402488Dipa2_mdrug induced psychomotor activation 2 (mouse)Not determined73842154872421684Mouse
4142102Tailq5_mtail length QTL 5 (mouse)Not determined3349772758148965Mouse
4141909W10q18_mweight 10 weeks QTL 18 (mouse)Not determined3349772758148965Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
1357883Epfq5_mepididymal fat pad weight QTL 5 (mouse)Not determined73349772758148965Mouse
10045622Heal20_mwound healing/regeneration 20 (mouse)Not determined73431688768317043Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
4142218W6q17_mweight 6 weeks QTL 17 (mouse)Not determined3349772758148965Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse
25314301Vmm3_mvariable multisystem mineralization 3, lung (mouse)73729942572049748Mouse

Markers in Region
D17911  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38745,461,775 - 45,461,935UniSTSGRCm38
MGSCv37752,717,145 - 52,717,305UniSTSGRCm37
Celera740,917,825 - 40,917,985UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map7B5UniSTS
cM Map723.0UniSTS
Whitehead_YAC7 UniSTS
Bax  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37752,720,579 - 52,721,625UniSTSGRCm37
MGSCv37752,720,605 - 52,721,422UniSTSGRCm37
MGSCv37752,720,578 - 52,721,390UniSTSGRCm37
Celera740,921,256 - 40,922,068UniSTS
Celera740,921,257 - 40,922,303UniSTS
Celera740,921,283 - 40,922,100UniSTS
Cytogenetic Map7B5UniSTS
cM Map723.0UniSTS
cM Map723.0UniSTS
PMC27116P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38745,466,026 - 45,466,119UniSTSGRCm38
MGSCv37752,721,396 - 52,721,489UniSTSGRCm37
Celera740,922,074 - 40,922,167UniSTS
Cytogenetic Map7B5UniSTS
cM Map723.0UniSTS
Bax  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38745,465,209 - 45,466,255UniSTSGRCm38
MGSCv37752,720,579 - 52,721,625UniSTSGRCm37
Celera740,921,257 - 40,922,303UniSTS
Cytogenetic Map7B5UniSTS
cM Map723.0UniSTS
Bax  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38745,465,208 - 45,466,020UniSTSGRCm38
MGSCv37752,720,578 - 52,721,390UniSTSGRCm37
Celera740,921,256 - 40,922,068UniSTS
Cytogenetic Map7B5UniSTS
cM Map723.0UniSTS
Bax  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7B5UniSTS
cM Map723.0UniSTS
Bax  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38745,465,235 - 45,466,052UniSTSGRCm38
MGSCv37752,720,605 - 52,721,422UniSTSGRCm37
Celera740,921,283 - 40,922,100UniSTS
Cytogenetic Map7B5UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001411994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011250780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB029557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC151602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF339055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV355155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY095934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY308683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ078904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT963044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L22472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000033093   ⟹   ENSMUSP00000033093
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,111,121 - 45,116,322 (-)Ensembl
GRCm38.p6 Ensembl745,461,697 - 45,466,898 (-)Ensembl
Ensembl Acc Id: ENSMUST00000210019   ⟹   ENSMUSP00000147753
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,114,677 - 45,116,202 (-)Ensembl
GRCm38.p6 Ensembl745,465,253 - 45,466,778 (-)Ensembl
Ensembl Acc Id: ENSMUST00000210392   ⟹   ENSMUSP00000148265
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,111,291 - 45,116,255 (-)Ensembl
GRCm38.p6 Ensembl745,461,867 - 45,466,831 (-)Ensembl
Ensembl Acc Id: ENSMUST00000211195   ⟹   ENSMUSP00000148182
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,114,613 - 45,116,199 (-)Ensembl
GRCm38.p6 Ensembl745,465,189 - 45,466,775 (-)Ensembl
Ensembl Acc Id: ENSMUST00000211365   ⟹   ENSMUSP00000148240
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,111,121 - 45,116,260 (-)Ensembl
GRCm38.p6 Ensembl745,461,697 - 45,466,836 (-)Ensembl
Ensembl Acc Id: ENSMUST00000211615
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,112,584 - 45,115,468 (-)Ensembl
GRCm38.p6 Ensembl745,463,160 - 45,466,044 (-)Ensembl
RefSeq Acc Id: NM_001411994   ⟹   NP_001398923
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,111,126 - 45,116,261 (-)NCBI
RefSeq Acc Id: NM_001411995   ⟹   NP_001398924
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,111,126 - 45,116,261 (-)NCBI
RefSeq Acc Id: NM_001411996   ⟹   NP_001398925
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,111,126 - 45,116,261 (-)NCBI
RefSeq Acc Id: NM_007527   ⟹   NP_031553
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,111,126 - 45,116,261 (-)NCBI
GRCm38745,461,695 - 45,466,898 (-)NCBI
MGSCv37752,717,065 - 52,722,268 (-)RGD
Celera740,917,745 - 40,922,946 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011250780   ⟹   XP_011249082
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,111,124 - 45,116,332 (-)NCBI
GRCm38745,461,700 - 45,466,903 (-)NCBI
Sequence:
RefSeq Acc Id: NP_031553   ⟸   NM_007527
- Peptide Label: isoform 1
- UniProtKB: Q07813 (UniProtKB/Swiss-Prot),   Q544Z6 (UniProtKB/TrEMBL),   Q3TXJ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011249082   ⟸   XM_011250780
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSMUSP00000148240   ⟸   ENSMUST00000211365
Ensembl Acc Id: ENSMUSP00000148182   ⟸   ENSMUST00000211195
Ensembl Acc Id: ENSMUSP00000148265   ⟸   ENSMUST00000210392
Ensembl Acc Id: ENSMUSP00000033093   ⟸   ENSMUST00000033093
Ensembl Acc Id: ENSMUSP00000147753   ⟸   ENSMUST00000210019
RefSeq Acc Id: NP_001398924   ⟸   NM_001411995
- Peptide Label: isoform 3
- UniProtKB: A0A165ELP6 (UniProtKB/TrEMBL),   A0A1B0GT81 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001398925   ⟸   NM_001411996
- Peptide Label: isoform 4
- UniProtKB: A0A165ELP6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001398923   ⟸   NM_001411994
- Peptide Label: isoform 2
- UniProtKB: A0A1B0GTA4 (UniProtKB/TrEMBL),   Q8K3J2 (UniProtKB/TrEMBL)
Protein Domains
Bcl-2 Bcl-2 homology region 1-3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q07813-F1-model_v2 AlphaFold Q07813 1-192 view protein structure

Promoters
RGD ID:8664029
Promoter ID:EPDNEW_M10044
Type:initiation region
Name:Bax_1
Description:Mus musculus BCL2-associated X protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38745,466,837 - 45,466,897EPDNEW
RGD ID:6840691
Promoter ID:MM_KWN:50405
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_007527,   UC009GVH.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36752,721,761 - 52,722,512 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99702 AgrOrtholog
Ensembl Genes ENSMUSG00000003873 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000033093 ENTREZGENE
  ENSMUST00000033093.10 UniProtKB/Swiss-Prot
  ENSMUST00000210392 ENTREZGENE
  ENSMUST00000211365 ENTREZGENE
Gene3D-CATH 1.10.437.10 UniProtKB/Swiss-Prot
InterPro Bcl-2_BH1-3 UniProtKB/Swiss-Prot
  Bcl2-like UniProtKB/Swiss-Prot
  Bcl2_BH1_motif_CS UniProtKB/Swiss-Prot
  Bcl2_BH2_motif_CS UniProtKB/Swiss-Prot
  Bcl2_BH3_motif_CS UniProtKB/Swiss-Prot
  Blc2-like_sf UniProtKB/Swiss-Prot
  Blc2_fam UniProtKB/Swiss-Prot
KEGG Report mmu:12028 UniProtKB/Swiss-Prot
MGD MGI:99702 ENTREZGENE
NCBI Gene 12028 ENTREZGENE
PANTHER PTHR11256 UniProtKB/Swiss-Prot
  PTHR11256:SF42 UniProtKB/Swiss-Prot
Pfam Bcl-2 UniProtKB/Swiss-Prot
PharmGKB BAX RGD
PhenoGen Bax PhenoGen
PRINTS BCL2FAMILY UniProtKB/Swiss-Prot
PROSITE BCL2_FAMILY UniProtKB/Swiss-Prot
  BH1 UniProtKB/Swiss-Prot
  BH2 UniProtKB/Swiss-Prot
  BH3 UniProtKB/Swiss-Prot
SMART BCL UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56854 UniProtKB/Swiss-Prot
UniProt A0A165ELP6 ENTREZGENE, UniProtKB/TrEMBL
  A0A1B0GS13_MOUSE UniProtKB/TrEMBL
  A0A1B0GT35_MOUSE UniProtKB/TrEMBL
  A0A1B0GT81 ENTREZGENE, UniProtKB/TrEMBL
  A0A1B0GTA4 ENTREZGENE, UniProtKB/TrEMBL
  BAX_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TXJ7 ENTREZGENE, UniProtKB/TrEMBL
  Q544Z6 ENTREZGENE, UniProtKB/TrEMBL
  Q8K3J2 ENTREZGENE, UniProtKB/TrEMBL
  Q9R0K9_MOUSE UniProtKB/TrEMBL