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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10226
Species: Mus musculus
RGD Object: Gene
Symbol: Bax
Name: BCL2-associated X protein
Acc ID: CHEBI:26267
Term: proanthocyanidin
Definition: A flavonoid oligomer obtained by the the condensation of two or more units of hydroxyflavans.
Chemical ID: MESH:D044945
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDProanthocyanidins results in increased expression of BAX mRNA; Proanthocyanidins results in increased expression of BAX proteinPMID:29654773
Baxmultiple interactionsISOBax (Rattus norvegicus)6480464CTDProanthocyanidins inhibits the reaction [Doxorubicin results in increased expression of BAX mRNA]; Proanthocyanidins inhibits the reaction [Doxorubicin results in increased expression of BAX protein]PMID:18611398
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