Gata4 (GATA binding protein 4) - Rat Genome Database

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Gene: Gata4 (GATA binding protein 4) Mus musculus
Analyze
Symbol: Gata4
Name: GATA binding protein 4
RGD ID: 737141
MGI Page MGI
Description: Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription coactivator binding activity. Involved in several processes, including heart development; negative regulation of cell death; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including embryonic morphogenesis; heart development; and male gonad development. Located in chromatin and nucleus. Is expressed in several structures, including early conceptus; embryo mesenchyme; gut; heart; and reproductive system. Used to study atrial heart septal defect 2 and congenital diaphragmatic hernia. Human ortholog(s) of this gene implicated in congenital heart disease (multiple). Orthologous to human GATA4 (GATA binding protein 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Gata; Gata-4; GATA-binding factor 4; GATA-binding protein 4; transcription factor GATA-4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391463,436,363 - 63,509,161 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1463,436,371 - 63,509,141 (-)EnsemblGRCm39 Ensembl
GRCm381463,198,914 - 63,271,712 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1463,198,922 - 63,271,692 (-)EnsemblGRCm38mm10GRCm38
MGSCv371463,817,752 - 63,864,097 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361462,153,032 - 62,199,370 (-)NCBIMGSCv36mm8
Celera1460,962,648 - 61,008,982 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1433.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dichloroethane  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
1D-myo-inositol 1,4,5-trisphosphate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dimethyl-4-tridecylmorpholine  (EXP)
2-ethoxyethanol  (ISO)
2-hydroxypropanoic acid  (EXP)
2-methoxyethanol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (EXP)
5-azacytidine  (ISO)
5-fluorouracil  (EXP)
5-hydroxytryptophan  (EXP)
acetamide  (ISO)
acetic acid  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
aldosterone  (ISO)
all-trans-retinoic acid  (EXP,ISO)
allethrin  (ISO)
ammonium chloride  (ISO)
androgen antagonist  (ISO)
arecoline  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bosentan  (EXP,ISO)
carbamazepine  (ISO)
carbon monoxide  (EXP)
carvedilol  (ISO)
crocidolite asbestos  (ISO)
curcumin  (EXP)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
D-glucose  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (EXP,ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
dimethyl sulfoxide  (ISO)
dipentyl phthalate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
ethanol  (EXP)
fenofibrate  (ISO)
fenvalerate  (ISO)
fluoranthene  (EXP)
flusilazole  (EXP)
fonofos  (ISO)
fulvestrant  (ISO)
glucose  (EXP)
glyphosate  (ISO)
heparin  (ISO)
homocysteine  (ISO)
hydrogen cyanide  (EXP)
hydrogen peroxide  (EXP)
icariin  (EXP)
irinotecan  (ISO)
isoprenaline  (EXP,ISO)
L-ascorbic acid  (EXP)
latrunculin B  (ISO)
lipopolysaccharide  (ISO)
methylmercury chloride  (ISO)
metoprolol  (ISO)
mifepristone  (EXP)
mithramycin  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
nicotine  (ISO)
nitrofen  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phenylephrine  (EXP,ISO)
phorbol 13-acetate 12-myristate  (EXP)
pirinixic acid  (EXP,ISO)
platycodin D  (ISO)
potassium cyanide  (EXP)
probucol  (ISO)
progesterone  (EXP)
prostaglandin F2alpha  (ISO)
pyrogallol  (EXP)
quercetin  (ISO)
rac-lactic acid  (EXP)
remdesivir  (EXP)
ribavirin  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
tadalafil  (EXP)
tamoxifen  (EXP)
terbufos  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (EXP)
tributylstannane  (ISO)
triclosan  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
warfarin  (ISO)
Y-27632  (ISO)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aortic valve morphogenesis  (ISO)
atrial septum morphogenesis  (ISO)
atrial septum primum morphogenesis  (IMP)
atrial septum secundum morphogenesis  (ISO)
atrioventricular canal development  (IGI)
atrioventricular valve formation  (IGI)
atrioventricular valve morphogenesis  (IGI,TAS)
cardiac muscle cell differentiation  (IGI,IMP,ISO,NAS)
cardiac muscle cell proliferation  (IGI)
cardiac muscle hypertrophy in response to stress  (IMP)
cardiac muscle tissue development  (IGI)
cardiac muscle tissue regeneration  (IDA)
cardiac right ventricle morphogenesis  (IMP)
cardiac septum development  (IGI)
cell fate commitment  (IBA)
cell growth involved in cardiac muscle cell development  (ISO)
cell-cell signaling  (IMP)
cellular response to follicle-stimulating hormone stimulus  (IDA)
cellular response to glucose stimulus  (ISO)
cellular response to gonadotropin stimulus  (IDA)
diaphragm morphogenesis  (TAS)
embryonic digestive tract morphogenesis  (IMP)
embryonic foregut morphogenesis  (IMP)
embryonic heart tube anterior/posterior pattern specification  (IMP)
embryonic heart tube development  (IMP)
embryonic morphogenesis  (IMP)
endocardial cushion development  (IGI,IMP,ISO)
endoderm formation  (IMP)
epithelial cell fate commitment  (IMP)
gastrulation with mouth forming second  (IMP)
heart development  (IMP)
heart looping  (IMP)
heart morphogenesis  (IMP)
in utero embryonic development  (IMP)
intestinal epithelial cell differentiation  (ISO)
lung lobe formation  (IMP)
lung morphogenesis  (TAS)
male gonad development  (ISO)
mitral valve formation  (TAS)
negative regulation of apoptotic process  (IDA)
negative regulation of apoptotic signaling pathway  (IDA)
negative regulation of autophagy  (ISO)
negative regulation of cardiac muscle cell apoptotic process  (IGI)
negative regulation of connective tissue replacement  (IDA)
negative regulation of gene expression  (IDA)
negative regulation of oxidative stress-induced cell death  (IDA)
negative regulation of transcription by RNA polymerase II  (IBA)
outflow tract morphogenesis  (TAS)
positive regulation of angiogenesis  (IDA)
positive regulation of BMP signaling pathway  (ISO)
positive regulation of cardiac muscle cell proliferation  (IGI)
positive regulation of cell cycle  (IDA)
positive regulation of DNA-templated transcription  (IDA,ISO)
positive regulation of ERK1 and ERK2 cascade  (IDA)
positive regulation of gene expression  (IDA,TAS)
positive regulation of protein phosphorylation  (IDA)
positive regulation of transcription by RNA polymerase II  (IBA,IDA,IGI,IMP,ISO)
positive regulation of vascular endothelial growth factor production  (IDA)
regulation of cardiac muscle cell contraction  (ISO)
regulation of cardiac muscle cell proliferation  (IMP)
regulation of DNA-templated transcription  (IDA,ISO,TAS)
regulation of gene expression  (IDA,IGI)
regulation of protein kinase B signaling  (IDA)
regulation of transcription by RNA polymerase II  (IDA)
response to estrogen  (IDA)
response to mechanical stimulus  (ISO)
response to retinoic acid  (IDA)
response to vitamin A  (ISO)
response to xenobiotic stimulus  (ISO)
seminiferous tubule development  (IMP)
Sertoli cell differentiation  (IMP)
signal transduction involved in regulation of gene expression  (IDA)
skeletal muscle cell differentiation  (NAS)
SMAD protein signal transduction  (IDA)
spermatogenesis  (IMP)
transdifferentiation  (ISO)
tricuspid valve formation  (TAS)
tube morphogenesis  (IGI)
vasculogenesis involved in coronary vascular morphogenesis  (TAS)
ventricular cardiac muscle tissue development  (IGI)
ventricular septum development  (IMP)
wound healing  (IDA)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aorta morphology  (IAGP)
abnormal aorta smooth muscle morphology  (IAGP)
abnormal atrioventricular cushion morphology  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal cardiac epithelial to mesenchymal transition  (IAGP)
abnormal cardiac outflow tract development  (IAGP)
abnormal cardiogenic mesoderm morphology  (IAGP)
abnormal cardiovascular development  (IAGP)
abnormal cardiovascular system morphology  (IAGP)
abnormal cardiovascular system physiology  (IAGP)
abnormal circulating hormone level  (IAGP)
abnormal conotruncal ridge morphology  (IAGP)
abnormal coronary vessel morphology  (IAGP)
abnormal developmental patterning  (IAGP)
abnormal diaphragm central tendon morphology  (IAGP)
abnormal diaphragm development  (IAGP)
abnormal dorsal-ventral axis patterning  (IAGP)
abnormal endometrium morphology  (IAGP)
abnormal enteric neural crest cell migration  (IAGP)
abnormal extraembryonic coelom morphology  (IAGP)
abnormal fetal cardiomyocyte morphology  (IAGP)
abnormal fetal cardiomyocyte proliferation  (IAGP)
abnormal fetal Leydig cell differentiation  (IAGP)
abnormal foregut morphology  (IAGP)
abnormal heart atrium morphology  (IAGP)
abnormal heart development  (IAGP)
abnormal heart layer morphology  (IAGP)
abnormal heart left ventricle outflow tract morphology  (IAGP)
abnormal heart morphology  (IAGP)
abnormal heart right ventricle outflow tract morphology  (IAGP)
abnormal heart size  (IAGP)
abnormal heart tube morphology  (IAGP)
abnormal heart ventricle morphology  (IAGP)
abnormal interventricular septum morphology  (IAGP)
abnormal lung development  (IAGP)
abnormal lung lobe morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal lung saccule morphology  (IAGP)
abnormal lung vasculature morphology  (IAGP)
abnormal lung volume  (IAGP)
abnormal muscle precursor cell morphology  (IAGP)
abnormal muscle precursor cell physiology  (IAGP)
abnormal myocardial fiber morphology  (IAGP)
abnormal myocardial trabeculae morphology  (IAGP)
abnormal myocardium compact layer morphology  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal ovary physiology  (IAGP)
abnormal primary sex determination  (IAGP)
abnormal response of heart to induced stress  (IAGP)
abnormal rostral-caudal axis patterning  (IAGP)
abnormal seminiferous tubule epithelium morphology  (IAGP)
abnormal Sertoli cell barrier function  (IAGP)
abnormal Sertoli cell morphology  (IAGP)
abnormal spermatid morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal trabecula carnea morphology  (IAGP)
abnormal truncus arteriosus septation  (IAGP)
abnormal vascular smooth muscle morphology  (IAGP)
abnormal visceral yolk sac morphology  (IAGP)
absent coronary vessels  (IAGP)
absent foregut  (IAGP)
absent heart  (IAGP)
absent heart tube  (IAGP)
aorta hypoplasia  (IAGP)
aorta stenosis  (IAGP)
aortic arch hypoplasia  (IAGP)
asthenozoospermia  (IAGP)
atrial septal defect  (IAGP)
atrioventricular cushion hypoplasia  (IAGP)
atrioventricular septal defect  (IAGP)
atrioventricular valve regurgitation  (IAGP)
cardia bifida  (IAGP)
cardiac hypertrophy  (IAGP)
common atrioventricular valve  (IAGP)
common ventricle  (IAGP)
complete atrioventricular septal defect  (IAGP)
congestive heart failure  (IAGP)
conotruncal ridge hypoplasia  (IAGP)
decreased blood oxygen saturation level  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased circulating estradiol level  (IAGP)
decreased circulating testosterone level  (IAGP)
decreased embryo size  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased fetal cardiomyocyte proliferation  (IAGP)
decreased litter size  (IAGP)
decreased male germ cell number  (IAGP)
decreased neuronal precursor cell number  (IAGP)
decreased ovary weight  (IAGP)
decreased response of heart to induced stress  (IAGP)
decreased seminal vesicle weight  (IAGP)
decreased sperm progressive motility  (IAGP)
decreased superovulation rate  (IAGP)
decreased testis weight  (IAGP)
decreased uterus weight  (IAGP)
delayed estrous cycle  (IAGP)
delayed heart looping  (IAGP)
delayed sexual maturation  (IAGP)
diaphragmatic hernia  (IAGP)
dilated aorta  (IAGP)
dilated heart  (IAGP)
dilated heart atrium  (IAGP)
dilated heart left ventricle  (IAGP)
dilated heart ventricle  (IAGP)
dilated respiratory conducting tube  (IAGP)
double outlet right ventricle  (IAGP)
edema  (IAGP)
embryonic growth arrest  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality between somite formation and embryo turning, complete penetrance  (IEA)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
failure of superovulation  (IAGP)
failure to gastrulate  (IAGP)
female infertility  (IAGP)
heart hypoplasia  (IAGP)
heart right ventricle hypoplasia  (IAGP)
hemorrhage  (IAGP)
hydrops fetalis  (IAGP)
increased apoptosis  (IAGP)
increased cardiomyocyte apoptosis  (IAGP)
increased male germ cell apoptosis  (IAGP)
inlet ventricular septal defect  (IAGP)
irregular heartbeat  (IAGP)
lethality during fetal growth through weaning, incomplete penetrance  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
multinucleated giant male germ cells  (IAGP)
neonatal lethality  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
oligozoospermia  (IAGP)
ostium primum atrial septal defect  (IAGP)
ovarian follicular cyst  (IAGP)
ovary cyst  (IAGP)
pallor  (IAGP)
patent cardiac foramen ovale  (IAGP)
pericardial effusion  (IAGP)
persistent truncus arteriosis  (IAGP)
polydactyly  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
primary sex reversal  (IAGP)
pulmonary edema  (IAGP)
pulmonary valve stenosis  (IAGP)
reduced female fertility  (IAGP)
reduced male fertility  (IAGP)
seminiferous tubule degeneration  (IAGP)
sinus venosus atrial septal defect  (IAGP)
skin edema  (IAGP)
small liver  (IAGP)
small ovary  (IAGP)
small testis  (IAGP)
testicular atrophy  (IAGP)
thick aortic valve  (IAGP)
thick pulmonary valve  (IAGP)
thin myocardium  (IAGP)
thin myocardium compact layer  (IAGP)
thin ventricle myocardium compact layer  (IAGP)
thin ventricular wall  (IAGP)
true hermaphroditism  (IAGP)
unbalanced complete common atrioventricular canal  (IAGP)
ventricular myocardium compact layer hypoplasia  (IAGP)
ventricular septal defect  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Alteration in methylation pattern of GATA-4 promoter region in vitamin A-deficient offspring's heart. Feng Y, etal., J Nutr Biochem. 2013 Jul;24(7):1373-80. doi: 10.1016/j.jnutbio.2012.11.005. Epub 2013 Jan 17.
2. GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. Garg V, etal., Nature. 2003 Jul 24;424(6947):443-7. Epub 2003 Jul 6.
3. Utilization of Whole Exome Sequencing to Identify Causative Mutations in Familial Congenital Heart Disease. LaHaye S, etal., Circ Cardiovasc Genet. 2016 Aug;9(4):320-9. doi: 10.1161/CIRCGENETICS.115.001324. Epub 2016 Jul 14.
4. Involvement of a novel GATA4 mutation in atrial septal defects. Liu XY, etal., Int J Mol Med. 2011 Jul;28(1):17-23. doi: 10.3892/ijmm.2011.638. Epub 2011 Mar 3.
5. Increase in cardiac M(2)-muscarinic receptor expression is regulated by GATA binding protein 4 (GATA-4) in streptozotocin-induced diabetic rats. Mar GY, etal., Int J Cardiol. 2012 Jan 29.
6. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. MGD IEA MGD IEA
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. Pulmonary hypertension-induced GATA4 activation in the right ventricle. Park AM, etal., Hypertension. 2010 Dec;56(6):1145-51. doi: 10.1161/HYPERTENSIONAHA.110.160515. Epub 2010 Nov 8.
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Phenanthrene exposure causes cardiac arrhythmia in embryonic zebrafish via perturbing calcium handling. Zhang Y, etal., Aquat Toxicol. 2013 Jul 29;142-143C:26-32. doi: 10.1016/j.aquatox.2013.07.014.
Additional References at PubMed
PMID:7647471   PMID:7665171   PMID:7717974   PMID:8007990   PMID:8045339   PMID:8083222   PMID:8455608   PMID:8582296   PMID:8660897   PMID:8754853   PMID:8786143   PMID:8812463  
PMID:9053305   PMID:9079680   PMID:9096102   PMID:9119112   PMID:9136932   PMID:9136933   PMID:9171826   PMID:9231805   PMID:9256344   PMID:9299119   PMID:9367431   PMID:9420335  
PMID:9500551   PMID:9502734   PMID:9566909   PMID:9584153   PMID:9621431   PMID:9636081   PMID:9671576   PMID:9722184   PMID:9738004   PMID:9811571   PMID:9832509   PMID:9834187  
PMID:9876177   PMID:9927675   PMID:10021345   PMID:10067876   PMID:10079226   PMID:10331979   PMID:10349636   PMID:10364163   PMID:10393122   PMID:10518495   PMID:10772805   PMID:10779506  
PMID:10888889   PMID:10892744   PMID:10922068   PMID:10926756   PMID:10964476   PMID:11040213   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11231080   PMID:11245568   PMID:11297508  
PMID:11298452   PMID:11356841   PMID:11481322   PMID:11572777   PMID:11724781   PMID:11784093   PMID:11839816   PMID:11841924   PMID:11864602   PMID:11923206   PMID:11937486   PMID:11973269  
PMID:12060663   PMID:12130579   PMID:12149478   PMID:12163407   PMID:12194849   PMID:12213678   PMID:12223418   PMID:12413896   PMID:12464436   PMID:12466851   PMID:12477932   PMID:12530677  
PMID:12538527   PMID:12571085   PMID:12606287   PMID:12606418   PMID:12645927   PMID:12670947   PMID:12676095   PMID:12761855   PMID:12781968   PMID:12801993   PMID:12933687   PMID:14502571  
PMID:14516662   PMID:14550786   PMID:14597408   PMID:14610273   PMID:14614148   PMID:14660441   PMID:14662776   PMID:14697368   PMID:14726490   PMID:14736744   PMID:14976138   PMID:14978031  
PMID:14985257   PMID:15062549   PMID:15082719   PMID:15100413   PMID:15162503   PMID:15169892   PMID:15172687   PMID:15178553   PMID:15199142   PMID:15211353   PMID:15256532   PMID:15271885  
PMID:15292239   PMID:15310850   PMID:15337742   PMID:15363409   PMID:15464586   PMID:15525990   PMID:15531365   PMID:15533830   PMID:15539431   PMID:15541382   PMID:15542826   PMID:15542856  
PMID:15601854   PMID:15618518   PMID:15653675   PMID:15764815   PMID:15766748   PMID:15767668   PMID:15829524   PMID:15830381   PMID:15836771   PMID:15843407   PMID:15843409   PMID:15843414  
PMID:15893302   PMID:15901664   PMID:15902305   PMID:15929941   PMID:15944188   PMID:15944199   PMID:15958514   PMID:15963769   PMID:15982862   PMID:15987774   PMID:16100707   PMID:16127717  
PMID:16137232   PMID:16141072   PMID:16141073   PMID:16162334   PMID:16166582   PMID:16199866   PMID:16199874   PMID:16210401   PMID:16223478   PMID:16236135   PMID:16260600   PMID:16314518  
PMID:16364283   PMID:16380715   PMID:16412416   PMID:16452489   PMID:16508137   PMID:16510507   PMID:16514068   PMID:16554359   PMID:16556595   PMID:16556596   PMID:16556914   PMID:16603706  
PMID:16618415   PMID:16621466   PMID:16624858   PMID:16728477   PMID:16822657   PMID:16847256   PMID:16870172   PMID:16887115   PMID:16914500   PMID:16940177   PMID:16945928   PMID:16983087  
PMID:17003108   PMID:17021344   PMID:17050624   PMID:17069789   PMID:17075876   PMID:17096405   PMID:17142311   PMID:17208226   PMID:17272516   PMID:17274974   PMID:17287250   PMID:17303760  
PMID:17332425   PMID:17339320   PMID:17350578   PMID:17360443   PMID:17366632   PMID:17369397   PMID:17445768   PMID:17451603   PMID:17468400   PMID:17473172   PMID:17526730   PMID:17540364  
PMID:17548362   PMID:17559079   PMID:17573777   PMID:17584735   PMID:17585069   PMID:17605826   PMID:17643447   PMID:17848526   PMID:17855431   PMID:17936262   PMID:17948256   PMID:17964124  
PMID:17975667   PMID:18000065   PMID:18028902   PMID:18173746   PMID:18206867   PMID:18212046   PMID:18267097   PMID:18276760   PMID:18287559   PMID:18316483   PMID:18328475   PMID:18351674  
PMID:18391012   PMID:18391526   PMID:18391535   PMID:18400219   PMID:18403409   PMID:18426912   PMID:18439490   PMID:18445271   PMID:18448090   PMID:18448675   PMID:18462699   PMID:18480752  
PMID:18552157   PMID:18554416   PMID:18568026   PMID:18577233   PMID:18591257   PMID:18635606   PMID:18692040   PMID:18725515   PMID:18775691   PMID:18781631   PMID:18812176   PMID:18814855  
PMID:18816845   PMID:18830417   PMID:18832096   PMID:18849322   PMID:18851995   PMID:18927154   PMID:19056886   PMID:19084512   PMID:19153222   PMID:19188439   PMID:19191218   PMID:19211672  
PMID:19228964   PMID:19325248   PMID:19411759   PMID:19479054   PMID:19491195   PMID:19501129   PMID:19543315   PMID:19551151   PMID:19578715   PMID:19592579   PMID:19622544   PMID:19706423  
PMID:19710168   PMID:19726871   PMID:19777587   PMID:19777593   PMID:19782130   PMID:19850025   PMID:19884258   PMID:19889636   PMID:19926876   PMID:19995889   PMID:20007915   PMID:20018673  
PMID:20041118   PMID:20080709   PMID:20081228   PMID:20106871   PMID:20123909   PMID:20139090   PMID:20159597   PMID:20167925   PMID:20185768   PMID:20185795   PMID:20194497   PMID:20211142  
PMID:20221402   PMID:20230754   PMID:20299672   PMID:20356956   PMID:20382855   PMID:20412781   PMID:20417598   PMID:20435031   PMID:20439457   PMID:20522556   PMID:20554972   PMID:20573702  
PMID:20581237   PMID:20596014   PMID:20664952   PMID:20665673   PMID:20679233   PMID:20691899   PMID:20692247   PMID:20705924   PMID:20833366   PMID:20925113   PMID:20962046   PMID:20962249  
PMID:20969841   PMID:20974940   PMID:21029371   PMID:21084315   PMID:21089072   PMID:21146513   PMID:21149574   PMID:21172404   PMID:21177287   PMID:21177343   PMID:21185281   PMID:21220346  
PMID:21243753   PMID:21248289   PMID:21255566   PMID:21262227   PMID:21267068   PMID:21283715   PMID:21311046   PMID:21330551   PMID:21379568   PMID:21385577   PMID:21427128   PMID:21447557  
PMID:21511879   PMID:21556048   PMID:21566084   PMID:21576353   PMID:21613325   PMID:21633169   PMID:21664901   PMID:21708977   PMID:21731673   PMID:21746915   PMID:21768366   PMID:21779394  
PMID:21791561   PMID:21828931   PMID:21839733   PMID:21873635   PMID:21878320   PMID:21896782   PMID:21930795   PMID:21983003   PMID:21991385   PMID:22046433   PMID:22056786   PMID:22095214  
PMID:22155005   PMID:22174950   PMID:22186409   PMID:22192413   PMID:22206758   PMID:22207710   PMID:22215809   PMID:22219180   PMID:22228770   PMID:22327294   PMID:22360967   PMID:22367967  
PMID:22412967   PMID:22431517   PMID:22431569   PMID:22434075   PMID:22461617   PMID:22525672   PMID:22553207   PMID:22554936   PMID:22558183   PMID:22577142   PMID:22581928   PMID:22589735  
PMID:22711842   PMID:22713603   PMID:22723016   PMID:22734001   PMID:22773876   PMID:22898775   PMID:22921202   PMID:22923619   PMID:22931955   PMID:22932696   PMID:22962329   PMID:22984617  
PMID:22996691   PMID:23006325   PMID:23006330   PMID:23048191   PMID:23071697   PMID:23087174   PMID:23091613   PMID:23095882   PMID:23102580   PMID:23102581   PMID:23132827   PMID:23142660  
PMID:23144723   PMID:23193166   PMID:23213408   PMID:23226341   PMID:23300479   PMID:23307821   PMID:23369715   PMID:23401851   PMID:23463509   PMID:23471215   PMID:23474895   PMID:23487795  
PMID:23536828   PMID:23554936   PMID:23558708   PMID:23582324   PMID:23589292   PMID:23595884   PMID:23606057   PMID:23704920   PMID:23747191   PMID:23751912   PMID:23769843   PMID:23788624  
PMID:23825962   PMID:23836893   PMID:23874227   PMID:23889939   PMID:23934214   PMID:23987514   PMID:24009392   PMID:24020834   PMID:24064357   PMID:24067354   PMID:24083978   PMID:24135228  
PMID:24168030   PMID:24268575   PMID:24284823   PMID:24293546   PMID:24335282   PMID:24352556   PMID:24355298   PMID:24367609   PMID:24380800   PMID:24391969   PMID:24415412   PMID:24415953  
PMID:24457600   PMID:24474767   PMID:24650916   PMID:24662306   PMID:24677751   PMID:24705356   PMID:24770533   PMID:24811170   PMID:24831012   PMID:24835466   PMID:24858909   PMID:24859004  
PMID:24866383   PMID:24878542   PMID:24899573   PMID:24912173   PMID:24927936   PMID:24929016   PMID:24932701   PMID:25035421   PMID:25063451   PMID:25142465   PMID:25190801   PMID:25209243  
PMID:25224227   PMID:25250575   PMID:25294942   PMID:25299188   PMID:25315346   PMID:25336743   PMID:25340657   PMID:25487574   PMID:25488664   PMID:25495347   PMID:25501827   PMID:25504289  
PMID:25504870   PMID:25516968   PMID:25569111   PMID:25590961   PMID:25611385   PMID:25668066   PMID:25668067   PMID:25670795   PMID:25739037   PMID:25758355   PMID:25787764   PMID:25807280  
PMID:25848000   PMID:25873328   PMID:25910836   PMID:25912687   PMID:25912690   PMID:25933105   PMID:26022694   PMID:26023924   PMID:26027919   PMID:26123487   PMID:26173459   PMID:26183893  
PMID:26199344   PMID:26321200   PMID:26341559   PMID:26354121   PMID:26386639   PMID:26388265   PMID:26449528   PMID:26473289   PMID:26477491   PMID:26489465   PMID:26493106   PMID:26510866  
PMID:26571399   PMID:26637965   PMID:26641717   PMID:26642209   PMID:26678830   PMID:26687508   PMID:26739565   PMID:26821812   PMID:26864965   PMID:26875865   PMID:26893347   PMID:26932670  
PMID:26939755   PMID:26973342   PMID:26974005   PMID:27117983   PMID:27150455   PMID:27179789   PMID:27245171   PMID:27256596   PMID:27292645   PMID:27320915   PMID:27321927   PMID:27565037  
PMID:27606604   PMID:27642710   PMID:27687577   PMID:27693352   PMID:27713415   PMID:27746116   PMID:27783597   PMID:27827449   PMID:27930333   PMID:27993987   PMID:28052057   PMID:28053183  
PMID:28057738   PMID:28087629   PMID:28164238   PMID:28167794   PMID:28218627   PMID:28302382   PMID:28346476   PMID:28360133   PMID:28387983   PMID:28426816   PMID:28472341   PMID:28484278  
PMID:28538179   PMID:28552557   PMID:28552559   PMID:28710293   PMID:28758902   PMID:28834610   PMID:28838957   PMID:28870993   PMID:28900034   PMID:28923684   PMID:28949961   PMID:29107559  
PMID:29155983   PMID:29197504   PMID:29257325   PMID:29311329   PMID:29324782   PMID:29394407   PMID:29444209   PMID:29445146   PMID:29454706   PMID:29509905   PMID:29523871   PMID:29540665  
PMID:29567480   PMID:29624520   PMID:29666070   PMID:29700203   PMID:29717129   PMID:29735715   PMID:29988383   PMID:30031905   PMID:30035248   PMID:30040984   PMID:30061196   PMID:30071018  
PMID:30128894   PMID:30151366   PMID:30306767   PMID:30347193   PMID:30428088   PMID:30530745   PMID:30541888   PMID:30580686   PMID:30715198   PMID:30735538   PMID:30759208   PMID:30787001  
PMID:30793514   PMID:30831323   PMID:30850578   PMID:30872705   PMID:30913328   PMID:30936836   PMID:30959515   PMID:30988352   PMID:31090492   PMID:31116734   PMID:31120883   PMID:31138536  
PMID:31143371   PMID:31201155   PMID:31206334   PMID:31260508   PMID:31308417   PMID:31335322   PMID:31366290   PMID:31397837   PMID:31422919   PMID:31628386   PMID:31688894   PMID:31748268  
PMID:31767831   PMID:31794640   PMID:31875961   PMID:31915320   PMID:32035085   PMID:32061766   PMID:32123336   PMID:32198202   PMID:32212902   PMID:32294451   PMID:32376282   PMID:32418930  
PMID:32438714   PMID:32450947   PMID:32452519   PMID:32655758   PMID:32759216   PMID:32827499   PMID:32855417   PMID:32883967   PMID:32916216   PMID:33004521   PMID:33094644   PMID:33230114  
PMID:33338666   PMID:33443158   PMID:33495473   PMID:33735101   PMID:33804107   PMID:33876316   PMID:33913477   PMID:33941892   PMID:33951437   PMID:34029137   PMID:34103494   PMID:34111600  
PMID:34351902   PMID:34373748   PMID:34487959   PMID:34491997   PMID:34517007   PMID:34699385   PMID:34884944   PMID:34908109   PMID:34918413   PMID:35017504   PMID:35063082   PMID:35075134  
PMID:35084365   PMID:35129866   PMID:35182466   PMID:35247020   PMID:35297517   PMID:35390228   PMID:35512705   PMID:35521669   PMID:35573693   PMID:35599622   PMID:35608036   PMID:35613264  
PMID:35729116   PMID:35973717   PMID:35988542   PMID:36028102   PMID:36100434   PMID:36150682   PMID:36165446   PMID:36233310   PMID:36263775   PMID:36333314   PMID:36347239   PMID:36522129  
PMID:36543770  


Genomics

Comparative Map Data
Gata4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391463,436,363 - 63,509,161 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1463,436,371 - 63,509,141 (-)EnsemblGRCm39 Ensembl
GRCm381463,198,914 - 63,271,712 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1463,198,922 - 63,271,692 (-)EnsemblGRCm38mm10GRCm38
MGSCv371463,817,752 - 63,864,097 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361462,153,032 - 62,199,370 (-)NCBIMGSCv36mm8
Celera1460,962,648 - 61,008,982 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1433.24NCBI
GATA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38811,676,935 - 11,760,002 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl811,676,959 - 11,760,002 (+)EnsemblGRCh38hg38GRCh38
GRCh37811,534,444 - 11,617,511 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36811,599,162 - 11,654,918 (+)NCBINCBI36Build 36hg18NCBI36
Build 34811,599,161 - 11,654,918NCBI
Celera810,690,994 - 10,746,848 (+)NCBICelera
Cytogenetic Map8p23.1NCBI
HuRef810,492,698 - 10,548,485 (+)NCBIHuRef
CHM1_1811,627,233 - 11,683,005 (+)NCBICHM1_1
T2T-CHM13v2.087,980,285 - 8,063,322 (-)NCBIT2T-CHM13v2.0
Gata4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21537,459,601 - 37,531,291 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1537,459,601 - 37,505,636 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1539,312,354 - 39,358,379 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01540,463,161 - 40,509,184 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01538,920,232 - 38,966,261 (-)NCBIRnor_WKY
Rnor_6.01546,386,703 - 46,458,679 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1546,386,712 - 46,432,965 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01550,151,497 - 50,197,708 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41542,472,793 - 42,519,569 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11542,488,492 - 42,535,269 (-)NCBI
Celera1537,143,928 - 37,189,874 (-)NCBICelera
RH 3.4 Map15261.71RGD
Cytogenetic Map15p12NCBI
Gata4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540352,987,644 - 53,029,267 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540352,958,318 - 53,029,267 (+)NCBIChiLan1.0ChiLan1.0
GATA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Mhudiblu_PPA_v087,442,921 - 7,526,731 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GATA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12526,126,172 - 26,211,474 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2526,127,853 - 26,182,989 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2526,784,428 - 26,835,191 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02526,280,507 - 26,366,154 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2526,280,510 - 26,337,654 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12526,235,249 - 26,286,037 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02526,131,847 - 26,182,607 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02526,283,313 - 26,334,650 (-)NCBIUU_Cfam_GSD_1.0
Gata4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049435,165,238 - 5,177,602 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366753,408,549 - 3,420,828 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GATA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1414,884,662 - 14,939,941 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11414,858,470 - 14,938,156 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21416,046,527 - 16,126,816 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GATA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.187,348,145 - 7,432,574 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl87,349,660 - 7,400,562 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605235,034,077 - 35,087,089 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gata4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475825,278,874 - 25,319,318 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475825,278,878 - 25,319,317 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir1a-1mmu-miR-1a-3pMirtarbaseexternal_infoqRT-PCR//Western blotFunctional MTI19188439
Mir1a-2mmu-miR-1a-3pMirtarbaseexternal_infoqRT-PCR//Western blotFunctional MTI19188439

Predicted Target Of
Summary Value
Count of predictions:2706
Count of miRNA genes:541
Interacting mature miRNAs:669
Transcripts:ENSMUST00000067417, ENSMUST00000118022, ENSMUST00000121312, ENSMUST00000132122, ENSMUST00000137244, ENSMUST00000156782
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142999699463997133Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143033525064335381Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143033525064335381Mouse
1300625Cosz2_mcocaine seizure 2 (mouse)Not determined143504579768785736Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143743018571430320Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4033731974337319Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144296241676962593Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144296241676962593Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144303727077037418Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144306584777066045Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144306584777066045Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144945542583455556Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145228198486282125Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145376129687761529Mouse
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145393744087937440Mouse
10043889Cia52_mcollagen induced arthritis QTL 52 (mouse)Not determined145608238190082509Mouse
1301562Hwq1_mheart weight quantitative locus 1 (mouse)Not determined145654674590546941Mouse
1357565wrmod1_mwobbler modifier 1 (mouse)Not determined1458179640101859473Mouse
11039527Ccc2_mcolitis susceptibility in the Collaborative Cross 2 (mouse)145991861294138217Mouse
1300666Fembm2_mfemoral bone morphometry 2 (mouse)Not determined146239746096397680Mouse

Markers in Region
Gata4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371463,822,192 - 63,823,452UniSTSGRCm37
MGSCv371463,819,273 - 63,820,344UniSTSGRCm37
MGSCv371463,819,149 - 63,819,353UniSTSGRCm37
MGSCv371463,819,007 - 63,819,333UniSTSGRCm37
MGSCv371463,819,286 - 63,820,397UniSTSGRCm37
Celera1460,964,182 - 60,965,293UniSTS
Celera1460,963,903 - 60,964,229UniSTS
Celera1460,967,088 - 60,968,340UniSTS
Celera1460,964,169 - 60,965,240UniSTS
Celera1460,964,045 - 60,964,249UniSTS
Cytogenetic Map14D1UniSTS
cM Map1428.0UniSTS
cM Map1428.0UniSTS
cM Map1428.0UniSTS
cM Map1428.0UniSTS
U85046  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381463,200,151 - 63,200,285UniSTSGRCm38
MGSCv371463,818,988 - 63,819,122UniSTSGRCm37
Celera1460,963,884 - 60,964,018UniSTS
Cytogenetic Map14D1UniSTS
cM Map1428.0UniSTS
Gata4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14D1UniSTS
Gata4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381463,200,312 - 63,200,516UniSTSGRCm38
MGSCv371463,819,149 - 63,819,353UniSTSGRCm37
Celera1460,964,045 - 60,964,249UniSTS
Cytogenetic Map14D1UniSTS
cM Map1428.0UniSTS
Gata4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381463,200,436 - 63,201,507UniSTSGRCm38
MGSCv371463,819,273 - 63,820,344UniSTSGRCm37
Celera1460,964,169 - 60,965,240UniSTS
Cytogenetic Map14D1UniSTS
cM Map1428.0UniSTS
Gata4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381463,200,170 - 63,200,496UniSTSGRCm38
MGSCv371463,819,007 - 63,819,333UniSTSGRCm37
Celera1460,963,903 - 60,964,229UniSTS
Cytogenetic Map14D1UniSTS
cM Map1428.0UniSTS
Gata4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381463,203,355 - 63,204,615UniSTSGRCm38
MGSCv371463,822,192 - 63,823,452UniSTSGRCm37
Celera1460,967,088 - 60,968,340UniSTS
Cytogenetic Map14D1UniSTS
Gata4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381463,200,449 - 63,201,560UniSTSGRCm38
MGSCv371463,819,286 - 63,820,397UniSTSGRCm37
Celera1460,964,182 - 60,965,293UniSTS
Cytogenetic Map14D1UniSTS
Gata4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14D1UniSTS
Gata4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14D1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001310610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011244956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011244957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB075549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC090654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC090962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF179424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW558892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB044491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC137824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG088871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF582373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ436912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ436913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ436914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ436915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M98339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U85046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000067417   ⟹   ENSMUSP00000066927
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1463,436,371 - 63,482,720 (-)Ensembl
GRCm38.p6 Ensembl1463,198,922 - 63,245,271 (-)Ensembl
RefSeq Acc Id: ENSMUST00000118022   ⟹   ENSMUSP00000113891
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1463,436,371 - 63,482,697 (-)Ensembl
GRCm38.p6 Ensembl1463,198,922 - 63,245,248 (-)Ensembl
RefSeq Acc Id: ENSMUST00000121312   ⟹   ENSMUSP00000113451
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1463,436,373 - 63,451,056 (-)Ensembl
GRCm38.p6 Ensembl1463,198,924 - 63,213,607 (-)Ensembl
RefSeq Acc Id: ENSMUST00000132122   ⟹   ENSMUSP00000121008
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1463,478,551 - 63,509,141 (-)Ensembl
GRCm38.p6 Ensembl1463,241,102 - 63,271,692 (-)Ensembl
RefSeq Acc Id: ENSMUST00000137244   ⟹   ENSMUSP00000114279
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1463,478,564 - 63,508,573 (-)Ensembl
GRCm38.p6 Ensembl1463,241,115 - 63,271,124 (-)Ensembl
RefSeq Acc Id: ENSMUST00000156782   ⟹   ENSMUSP00000114369
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1463,478,564 - 63,508,573 (-)Ensembl
GRCm38.p6 Ensembl1463,241,115 - 63,271,124 (-)Ensembl
RefSeq Acc Id: NM_001310610   ⟹   NP_001297539
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391463,436,363 - 63,482,720 (-)NCBI
GRCm381463,198,914 - 63,245,271 (-)NCBI
Sequence:
RefSeq Acc Id: NM_008092   ⟹   NP_032118
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391463,436,363 - 63,482,720 (-)NCBI
GRCm381463,198,914 - 63,245,271 (-)NCBI
MGSCv371463,817,752 - 63,864,097 (-)RGD
Celera1460,962,648 - 61,008,982 (-)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011244956   ⟹   XP_011243258
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391463,436,370 - 63,509,161 (-)NCBI
GRCm381463,198,921 - 63,271,712 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011244957   ⟹   XP_011243259
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391463,436,370 - 63,508,582 (-)NCBI
GRCm381463,198,921 - 63,271,133 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032118   ⟸   NM_008092
- Peptide Label: isoform 2
- UniProtKB: Q9QZK4 (UniProtKB/Swiss-Prot),   Q08369 (UniProtKB/Swiss-Prot),   Q3UYJ1 (UniProtKB/TrEMBL),   A0A8C6H451 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011243258   ⟸   XM_011244956
- Peptide Label: isoform X1
- UniProtKB: E9PXW9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011243259   ⟸   XM_011244957
- Peptide Label: isoform X1
- UniProtKB: E9PXW9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001297539   ⟸   NM_001310610
- Peptide Label: isoform 1
- UniProtKB: E9PXW9 (UniProtKB/TrEMBL),   Q3UYJ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000113891   ⟸   ENSMUST00000118022
RefSeq Acc Id: ENSMUSP00000121008   ⟸   ENSMUST00000132122
RefSeq Acc Id: ENSMUSP00000066927   ⟸   ENSMUST00000067417
RefSeq Acc Id: ENSMUSP00000113451   ⟸   ENSMUST00000121312
RefSeq Acc Id: ENSMUSP00000114279   ⟸   ENSMUST00000137244
RefSeq Acc Id: ENSMUSP00000114369   ⟸   ENSMUST00000156782
Protein Domains
GATA-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q08369-F1-model_v2 AlphaFold Q08369 1-441 view protein structure

Promoters
RGD ID:8682696
Promoter ID:EPDNEW_M19379
Type:multiple initiation site
Name:Gata4_1
Description:Mus musculus GATA binding protein 4 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19380  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381463,245,238 - 63,245,298EPDNEW
RGD ID:8682700
Promoter ID:EPDNEW_M19380
Type:initiation region
Name:Gata4_2
Description:Mus musculus GATA binding protein 4 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19379  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381463,271,716 - 63,271,776EPDNEW
RGD ID:6824947
Promoter ID:MM_KWN:17184
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Kidney,   Liver,   Lung
Transcripts:NM_008092,   OTTMUST00000081055
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361463,863,666 - 63,864,417 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95664 AgrOrtholog
Ensembl Genes ENSMUSG00000021944 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000066927 ENTREZGENE
  ENSMUSP00000066927.4 UniProtKB/TrEMBL
  ENSMUSP00000113451.2 UniProtKB/TrEMBL
  ENSMUSP00000113891 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000114279.2 UniProtKB/TrEMBL
  ENSMUSP00000114369.2 UniProtKB/TrEMBL
  ENSMUSP00000121008.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000067417 ENTREZGENE
  ENSMUST00000067417.10 UniProtKB/TrEMBL
  ENSMUST00000118022 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000121312.2 UniProtKB/TrEMBL
  ENSMUST00000132122.2 UniProtKB/TrEMBL
  ENSMUST00000137244.8 UniProtKB/TrEMBL
  ENSMUST00000156782.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.50.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GATA_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_GATA_4/5/6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transcription_factor_GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14463 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95664 ENTREZGENE
NCBI Gene 14463 ENTREZGENE
PANTHER PTHR10071 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GATA-N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gata4 PhenoGen
PIRSF TF_GATA_4/5/6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS GATAZNFINGER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GATA_ZN_FINGER_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GATA_ZN_FINGER_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ZnF_GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C6H451 ENTREZGENE
  A4K4Z6_MOUSE UniProtKB/TrEMBL
  D3YTQ2_MOUSE UniProtKB/TrEMBL
  E9PXW9 ENTREZGENE, UniProtKB/TrEMBL
  GATA4_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UYJ1 ENTREZGENE, UniProtKB/TrEMBL
  Q8VI87_MOUSE UniProtKB/TrEMBL
  Q9QZK4 ENTREZGENE
UniProt Secondary B9EHF7 UniProtKB/Swiss-Prot
  P97491 UniProtKB/Swiss-Prot
  Q9QZK4 UniProtKB/Swiss-Prot