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Gene: Ncf4 (neutrophil cytosolic factor 4) Mus musculus
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Symbol: Ncf4
Name: neutrophil cytosolic factor 4
Description: Predicted to have phosphatidylinositol-3-phosphate binding activity; superoxide-generating NADPH oxidase activator activity; and superoxide-generating NADPH oxidase activity. Predicted to be involved in oxidation-reduction process and superoxide metabolic process. Localizes to cytoplasm. Is expressed in liver; lower urinary tract; stomach; and testis. Human ortholog(s) of this gene implicated in autosomal recessive chronic granulomatous disease cytochrome b-positive type III. Orthologous to human NCF4 (neutrophil cytosolic factor 4); PARTICIPATES IN Leishmaniasis pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI451400; NCF-4; neutrophil cytosol factor 4; neutrophil NADPH oxidase factor 4; p40-phox; p40phox
Orthologs:
Homo sapiens (human) : NCF4 (neutrophil cytosolic factor 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ncf4 (neutrophil cytosolic factor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncf4 (neutrophil cytosolic factor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : NCF4 (neutrophil cytosolic factor 4)
Canis lupus familiaris (dog) : NCF4 (neutrophil cytosolic factor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncf4 (neutrophil cytosolic factor 4)
Sus scrofa (pig) : NCF4 (neutrophil cytosolic factor 4)
Chlorocebus sabaeus (African green monkey) : NCF4 (neutrophil cytosolic factor 4)
Heterocephalus glaber (naked mole-rat) : Ncf4 (neutrophil cytosolic factor 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1578,244,801 - 78,262,580 (+)EnsemblGRCm38mm10GRCm38
GRCm381578,244,164 - 78,262,582 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371578,075,241 - 78,093,010 (+)NCBIGRCm37mm9NCBIm37
MGSCv361578,072,089 - 78,089,829 (+)NCBImm8
Celera1579,705,722 - 79,723,507 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ncf4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314272
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.