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Gene: Ncf4 (neutrophil cytosolic factor 4) Mus musculus
Symbol: Ncf4
Name: neutrophil cytosolic factor 4
Description: Predicted to have phosphatidylinositol-3-phosphate binding activity; superoxide-generating NADPH oxidase activator activity; and superoxide-generating NADPH oxidase activity. Predicted to be involved in oxidation-reduction process and superoxide metabolic process. Localizes to cytoplasm. Is expressed in liver; lower urinary tract; stomach; and testis. Human ortholog(s) of this gene implicated in autosomal recessive chronic granulomatous disease cytochrome b-positive type III. Orthologous to human NCF4 (neutrophil cytosolic factor 4); PARTICIPATES IN Leishmaniasis pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI451400; NCF-4; neutrophil cytosol factor 4; neutrophil NADPH oxidase factor 4; p40-phox; p40phox
Homo sapiens (human) : NCF4 (neutrophil cytosolic factor 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ncf4 (neutrophil cytosolic factor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncf4 (neutrophil cytosolic factor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : NCF4 (neutrophil cytosolic factor 4)
Canis lupus familiaris (dog) : NCF4 (neutrophil cytosolic factor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncf4 (neutrophil cytosolic factor 4)
Sus scrofa (pig) : NCF4 (neutrophil cytosolic factor 4)
Chlorocebus sabaeus (African green monkey) : NCF4 (neutrophil cytosolic factor 4)
Heterocephalus glaber (naked mole-rat) : Ncf4 (neutrophil cytosolic factor 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1578,244,801 - 78,262,580 (+)EnsemblGRCm38mm10GRCm38
GRCm381578,244,164 - 78,262,582 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371578,075,241 - 78,093,010 (+)NCBIGRCm37mm9NCBIm37
MGSCv361578,072,089 - 78,089,829 (+)NCBImm8
Celera1579,705,722 - 79,723,507 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ncf4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314272
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.