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Gene: Mmp3 (matrix metallopeptidase 3) Mus musculus
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Symbol: Mmp3
Name: matrix metallopeptidase 3
Description: Predicted to have metalloendopeptidase activity. Involved in several processes, including cellular response to amino acid stimulus; negative regulation of protein kinase B signaling; and positive regulation of oxidative stress-induced cell death. Localizes to the cytosol and mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); end stage renal failure; esophagus adenocarcinoma; osteoarthritis; and von Hippel-Lindau disease. Is expressed in several structures, including axial skeleton thoracic region; genitourinary system; jaw; lung; and oral epithelium. Orthologous to human MMP3 (matrix metallopeptidase 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EMS-2; matrix metalloproteinase 3; matrix metalloproteinase-3; MMP-3; progelatinase; SL-1; SLN-1; SLN1; Stmy1; STR-1; Str1; stromelysin 1; stromelysin-1; transin-1
Orthologs:
Homo sapiens (human) : MMP3 (matrix metallopeptidase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mmp3 (matrix metallopeptidase 3)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MMP3 (matrix metallopeptidase 3)
Canis lupus familiaris (dog) : MMP3 (matrix metallopeptidase 3 (stromelysin 1, progelatinase))
Sus scrofa (pig) : MMP3 (matrix metallopeptidase 3)
Chlorocebus sabaeus (African green monkey) : MMP3 (matrix metallopeptidase 3)
Heterocephalus glaber (naked mole-rat) : Mmp3 (matrix metallopeptidase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl97,445,822 - 7,455,975 (+)Ensembl
GRCm3897,445,822 - 7,455,975 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3797,445,822 - 7,455,975 (+)NCBIGRCm37mm9NCBIm37
MGSCv3697,445,822 - 7,455,975 (+)NCBImm8
Celera94,846,374 - 4,856,527 (+)NCBICelera
Cytogenetic Map9 A1NCBI
cM Map92.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mmp3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733756
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.