Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Arnt (aryl hydrocarbon receptor nuclear translocator) Mus musculus
Analyze
Symbol: Arnt
Name: aryl hydrocarbon receptor nuclear translocator
Description: Exhibits RNA polymerase II distal enhancer sequence-specific DNA binding activity; nuclear receptor activity; and protein heterodimerization activity. Predicted to contribute to DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including embryonic placenta development; positive regulation of macromolecule metabolic process; and response to hypoxia. Localizes to the cytoplasm; nucleus; and transcription factor complex. Human ortholog(s) of this gene implicated in renal cell carcinoma. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human ARNT (aryl hydrocarbon receptor nuclear translocator); PARTICIPATES IN aryl hydrocarbon receptor signaling pathway; hypoxia inducible factor pathway; renal cell carcinoma pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (S)-naringenin; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bHLHe2; D3Ertd557e; dioxin receptor, nuclear translocator; Drnt; ESTM42; HIF-1-beta; HIF1-beta; Hif1b; hypoxia-inducible factor 1-beta; KIAA4051; mKIAA4051; W08714
Orthologs:
Homo sapiens (human) : ARNT (aryl hydrocarbon receptor nuclear translocator)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Arnt (aryl hydrocarbon receptor nuclear translocator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arnt (aryl hydrocarbon receptor nuclear translocator)
Pan paniscus (bonobo/pygmy chimpanzee) : ARNT (aryl hydrocarbon receptor nuclear translocator)
Canis lupus familiaris (dog) : ARNT (aryl hydrocarbon receptor nuclear translocator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arnt (aryl hydrocarbon receptor nuclear translocator)
Sus scrofa (pig) : ARNT (aryl hydrocarbon receptor nuclear translocator)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl395,434,388 - 95,497,240 (+)Ensembl
GRCm38395,434,367 - 95,497,240 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37395,238,312 - 95,301,162 (+)NCBIGRCm37mm9NCBIm37
MGSCv36395,519,832 - 95,581,692 (+)NCBImm8
Celera396,865,861 - 96,928,345 (+)NCBICelera
Cytogenetic Map3 F2.1NCBI
cM Map340.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Arnt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10189
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.