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Gene: Arnt (aryl hydrocarbon receptor nuclear translocator) Mus musculus
Symbol: Arnt
Name: aryl hydrocarbon receptor nuclear translocator
Description: Exhibits RNA polymerase II distal enhancer sequence-specific DNA binding activity; nuclear receptor activity; and protein heterodimerization activity. Predicted to contribute to DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including embryonic placenta development; positive regulation of macromolecule metabolic process; and response to hypoxia. Localizes to the cytoplasm; nucleus; and transcription factor complex. Human ortholog(s) of this gene implicated in renal cell carcinoma. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human ARNT (aryl hydrocarbon receptor nuclear translocator); PARTICIPATES IN aryl hydrocarbon receptor signaling pathway; hypoxia inducible factor pathway; renal cell carcinoma pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (S)-naringenin; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bHLHe2; D3Ertd557e; dioxin receptor, nuclear translocator; Drnt; ESTM42; HIF-1-beta; HIF1-beta; Hif1b; hypoxia-inducible factor 1-beta; KIAA4051; mKIAA4051; W08714
Homo sapiens (human) : ARNT (aryl hydrocarbon receptor nuclear translocator)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Arnt (aryl hydrocarbon receptor nuclear translocator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arnt (aryl hydrocarbon receptor nuclear translocator)
Pan paniscus (bonobo/pygmy chimpanzee) : ARNT (aryl hydrocarbon receptor nuclear translocator)
Canis lupus familiaris (dog) : ARNT (aryl hydrocarbon receptor nuclear translocator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arnt (aryl hydrocarbon receptor nuclear translocator)
Sus scrofa (pig) : ARNT (aryl hydrocarbon receptor nuclear translocator)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl395,434,388 - 95,497,240 (+)Ensembl
GRCm38395,434,367 - 95,497,240 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37395,238,312 - 95,301,162 (+)NCBIGRCm37mm9NCBIm37
MGSCv36395,519,832 - 95,581,692 (+)NCBImm8
Celera396,865,861 - 96,928,345 (+)NCBICelera
Cytogenetic Map3 F2.1NCBI
cM Map340.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Arnt
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10189
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.