Pgr (progesterone receptor) - Rat Genome Database

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Gene: Pgr (progesterone receptor) Mus musculus
Analyze
Symbol: Pgr
Name: progesterone receptor
RGD ID: 11092
MGI Page MGI
Description: Enables DNA-binding transcription factor activity, RNA polymerase II-specific; steroid hormone receptor activity; and transcription cis-regulatory region binding activity. Acts upstream of or within several processes, including animal organ development; paracrine signaling; and progesterone receptor signaling pathway. Predicted to be located in several cellular components, including axon terminus; dendritic spine; and perikaryon. Is expressed in brain; genitourinary system; lung; and thymus. Human ortholog(s) of this gene implicated in endometriosis; hyperprolactinemia; and obesity. Orthologous to human PGR (progesterone receptor).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 9930019P03Rik; BB114106; ENSMUSG00000074510; expressed sequence BB114106; NR3; NR3C3; nuclear receptor subfamily 3 group C member 3; P; PR; PR-A; PR-B; predicted gene, ENSMUSG00000074510
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3998,890,017 - 8,968,612 (+)NCBIGRCm39mm39
GRCm39 Ensembl98,899,834 - 8,968,612 (+)Ensembl
GRCm3898,898,900 - 8,968,611 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl98,899,833 - 8,968,611 (+)EnsemblGRCm38mm10GRCm38
MGSCv3798,899,833 - 8,968,611 (+)NCBIGRCm37mm9NCBIm37
MGSCv3698,862,303 - 8,926,995 (+)NCBImm8
Celera96,279,529 - 6,348,253 (+)NCBICelera
Cytogenetic Map9A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(20S)-ginsenoside Rh1  (ISO)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(R)-camphor  (ISO)
(R)-linalyl acetate  (ISO)
(S)-naringenin  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP,ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (ISO)
1-(3-(trifluoromethyl)phenyl)piperazine  (ISO)
1-benzylpiperazine  (ISO)
1-Hydroxypyrene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17alpha-hydroxyprogesterone  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,3',4,4',5,5'-Heptachlorobiphenyl  (ISO)
2,3,4,5-Tetrachloro-4'-biphenylol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester  (ISO)
26-hydroxycholesterol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol  (ISO)
3,5-di-tert-Butyl-4-hydroxybenzaldehyde  (ISO)
3,6-diaminoacridine  (ISO)
3,7-dihydropurine-6-thione  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-methylcholanthrene  (ISO)
4'-epidoxorubicin  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxy-17beta-estradiol  (EXP)
4-nonylphenol  (EXP,ISO)
4-terpineol  (ISO)
4-tert-butylphenol  (ISO)
4-tert-Octylphenol  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
6-oxocampestanol  (ISO)
8-Br-cAMP  (ISO)
adefovir pivoxil  (ISO)
afimoxifene  (ISO)
alachlor  (ISO)
aldicarb  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (ISO)
alpha-Methylstyrene  (ISO)
alpha-naphthoflavone  (ISO)
alpha-Zearalanol  (EXP)
alternariol  (ISO)
aminoglutethimide  (ISO)
amlodipine  (ISO)
ammonium sulfate  (ISO)
amsacrine  (ISO)
anastrozole  (ISO)
androgen antagonist  (ISO)
apigenin  (ISO)
aprepitant  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
artesunate  (ISO)
atrazine  (ISO)
bendiocarb  (ISO)
benzo[a]pyrene  (ISO)
beta-hexachlorocyclohexane  (ISO)
bexarotene  (ISO)
bicalutamide  (ISO)
bifenthrin  (ISO)
biochanin A  (ISO)
biphenyl-2-ol  (ISO)
biphenyl-4-ol  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol A dimethacrylate  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
budesonide  (ISO)
buta-1,3-diene  (EXP)
butylated hydroxyanisole  (EXP,ISO)
Butylbenzyl phthalate  (EXP,ISO)
Butylparaben  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
camphor  (ISO)
camptothecin  (ISO)
carbaryl  (ISO)
carbon nanotube  (EXP)
carfilzomib  (ISO)
chlordecone  (EXP,ISO)
chlorogenic acid  (ISO)
chlorpyrifos  (ISO)
Chorionic gonadotropin  (ISO)
chrysen-6-ol  (ISO)
Ciclesonide  (ISO)
ciclopirox  (ISO)
clomiphene  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
colforsin daropate hydrochloride  (EXP)
copper(II) chloride  (ISO)
coumestrol  (EXP,ISO)
Cuprizon  (ISO)
cyclohexanone  (ISO)
cyfluthrin  (ISO)
cyhalothrin  (ISO)
cypermethrin  (EXP,ISO)
cyproterone acetate  (ISO)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
danazol  (ISO)
DDD  (ISO)
DDE  (ISO)
DDT  (EXP,ISO)
delta-hexachlorocyclohexane  (ISO)
desogestrel  (ISO)
diarylheptanoid  (EXP,ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (EXP)
dieldrin  (ISO)
diethyl phthalate  (EXP,ISO)
diethylstilbestrol  (ISO)
difenoconazole  (ISO)
digitoxin  (ISO)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP,ISO)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
dronedarone  (ISO)
drospirenone  (ISO)
dydrogesterone  (ISO)
elcometrine  (ISO)
emetine  (ISO)
endosulfan  (ISO)
endrin  (ISO)
enzacamene  (ISO)
epoxiconazole  (ISO)
erucamide  (ISO)
Estradiol dipropionate  (EXP)
estriol  (ISO)
estrone  (ISO)
ethanol  (ISO)
ethyl myristate  (ISO)
etonogestrel  (ISO)
etoposide phosphate  (ISO)
exemestane  (ISO)
ezetimibe  (ISO)
fenhexamid  (ISO)
fenpyroximate  (ISO)
fenvalerate  (ISO)
fludioxonil  (ISO)
flunisolide  (ISO)
fluoxastrobin  (ISO)
flutamide  (ISO)
fluticasone  (ISO)
flutolanil  (ISO)
fulvestrant  (EXP,ISO)
galaxolide  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gamma-terpinene  (ISO)
geldanamycin  (ISO)
gemcitabine  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
geraniol  (ISO)
gestodene  (ISO)
ginsenoside Rb1  (ISO)
ginsenoside Re  (ISO)
ginsenoside Rg1  (ISO)
glutathione  (EXP)
glyceollin  (ISO)
glyphosate  (ISO)
Goserelin  (ISO)
heptachlor  (ISO)
Heptachlor epoxide  (ISO)
herbicide  (ISO)
hexestrol  (ISO)
hydrogen peroxide  (EXP)
icariin  (ISO)
ICI-164384  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
irilone  (ISO)
isoflavones  (ISO)
isophorone  (ISO)
isoprothiolane  (ISO)
kaempferol  (ISO)
kresoxim-methyl  (ISO)
lasofoxifene  (ISO)
Laurolactam  (ISO)
lead(II) chloride  (ISO)
letrozole  (ISO)
levonorgestrel  (ISO)
limonene  (ISO)
linalool  (ISO)
linalyl acetate  (ISO)
linuron  (ISO)
loteprednol etabonate  (ISO)
medroxyprogesterone  (ISO)
medroxyprogesterone acetate  (EXP,ISO)
megestrol acetate  (ISO)
melatonin  (ISO)
mercaptopurine  (ISO)
mercury dichloride  (ISO)
mestranol  (ISO)
methimazole  (EXP)
methomyl  (ISO)
methotrexate  (ISO)
methoxyacetic acid  (ISO)
methoxychlor  (EXP,ISO)
methyl laurate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
methylseleninic acid  (ISO)
methyltestosterone  (ISO)
mifepristone  (EXP,ISO)
Mitotane  (ISO)
mometasone furoate  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
Monobutylphthalate  (ISO)
mycophenolic acid  (ISO)
mycotoxin  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
nebivolol  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nonane  (ISO)
Nonylphenol  (EXP,ISO)
norethisterone  (ISO)
norgestimate  (ISO)
okadaic acid  (ISO)
ormeloxifene  (ISO)
Osajin  (ISO)
oseltamivir  (ISO)
oxaliplatin  (ISO)
oxamyl  (ISO)
oxybenzone  (ISO)
oxymetholone  (ISO)
p-tert-Amylphenol  (EXP,ISO)
p-tolualdehyde  (ISO)
paracetamol  (ISO)
pazopanib  (ISO)
PCB138  (EXP)
pentachlorophenol  (ISO)
pentobarbital  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenanthrene  (ISO)
phenol red  (ISO)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phthalic acid  (ISO)
phytoestrogen  (ISO)
picene  (ISO)
picoxystrobin  (ISO)
Pomiferin  (ISO)
potassium chloride  (ISO)
prochloraz  (ISO)
procymidone  (ISO)
progesterone  (EXP,ISO)
promegestone  (EXP,ISO)
propoxur  (ISO)
propylparaben  (ISO)
pterostilbene  (ISO)
puerarin  (ISO)
purine-6-thiol  (ISO)
pyrene  (ISO)
pyridaben  (ISO)
quercetin  (ISO)
radicicol  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
Rosavin  (ISO)
rotenone  (ISO)
RU 58668  (ISO)
rubitecan  (ISO)
S-methyl methanethiosulfonate  (ISO)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
silicon dioxide  (EXP)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
simazine  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium fluoride  (ISO)
sophoraflavanone B  (ISO)
staurosporine  (ISO)
stilben-4-ol  (ISO)
stilbene-4,4'-diol  (ISO)
sulindac sulfide  (ISO)
sulindac sulfone  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tamoxifen  (EXP,ISO)
tanespimycin  (EXP)
tea tree oil  (ISO)
tegaserod  (ISO)
Temsirolimus  (ISO)
teniposide  (ISO)
testosterone  (ISO)
Testosterone propionate  (EXP,ISO)
Tetrachlorobisphenol A  (ISO)
tetraphene  (ISO)
tibolone  (ISO)
ticlopidine  (ISO)
tolcapone  (ISO)
toxaphene  (ISO)
TRAM-34  (ISO)
trans-stilbene-4,4'-diol  (ISO)
triamcinolone  (ISO)
trichostatin A  (EXP,ISO)
trifloxystrobin  (ISO)
trimegestone  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP,ISO)
vorinostat  (ISO)
XL147  (EXP)
zearalenone  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal bone ossification  (IAGP)
abnormal branching of the mammary ductal tree  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal decidualization  (IAGP)
abnormal embryo attachment  (IAGP)
abnormal embryo development  (IAGP)
abnormal endometrial gland development  (IAGP)
abnormal endometrial gland morphology  (IAGP)
abnormal endometrium morphology  (IAGP)
abnormal female reproductive system morphology  (IAGP)
abnormal follicle stimulating hormone level  (IAGP)
abnormal humerus morphology  (IAGP)
abnormal internal female genitalia morphology  (IAGP)
abnormal lactation  (IAGP)
abnormal luminal closure  (IAGP)
abnormal mammary gland alveolus morphology  (IAGP)
abnormal mammary gland development  (IAGP)
abnormal mammary gland duct morphology  (IAGP)
abnormal mammary gland epithelium morphology  (IAGP)
abnormal mammary gland growth during pregnancy  (IAGP)
abnormal mammary gland morphology  (IAGP)
abnormal mammary gland physiology  (IAGP)
abnormal maternal decidual layer morphology  (IAGP)
abnormal mating receptivity  (IAGP)
abnormal myometrium morphology  (IAGP)
abnormal osteoclast morphology  (IAGP)
abnormal oviduct morphology  (IAGP)
abnormal ovulation  (IAGP)
abnormal placenta morphology  (IAGP)
abnormal postimplantation uterine environment  (IAGP)
abnormal reproductive system physiology  (IAGP)
abnormal response/metabolism to endogenous compounds  (IAGP)
abnormal sexual interaction  (IAGP)
abnormal tibia morphology  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal trophoblast giant cell proliferation  (IAGP)
abnormal uterine environment  (IAGP)
abnormal uterine receptivity  (IAGP)
abnormal uterine-embryonic axis  (IAGP)
abnormal uterus development  (IAGP)
abnormal uterus morphology  (IAGP)
abnormal uterus physiology  (IAGP)
abnormal uterus size  (IAGP)
abnormal vascular permeability  (IAGP)
abnormal vascular wound healing  (IAGP)
absent corpus luteum  (IAGP)
absent endometrial glands  (IAGP)
anovulation  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating luteinizing hormone level  (IAGP)
decreased circulating progesterone level  (IAGP)
decreased incidence of induced tumors  (IAGP)
decreased litter size  (IAGP)
decreased mammary gland epithelial cell proliferation  (IAGP)
decreased placental labyrinth size  (IAGP)
decreased uterine NK cell number  (IAGP)
decreased uterus weight  (IAGP)
dilated uterus  (IAGP)
early reproductive senescence  (IAGP)
endometrium fibrosis  (IAGP)
endometrium hyperplasia  (IAGP)
endometrium hypoplasia  (IAGP)
enlarged endometrial glands  (IAGP)
enlarged uterine horn  (IAGP)
enlarged uterus  (IAGP)
failure of embryo implantation  (IAGP)
female infertility  (IAGP)
impaired embryo implantation  (IAGP)
impaired luteinization  (IAGP)
impaired spacing of implantation sites  (IAGP)
improved glucose tolerance  (IAGP)
increased bone mass  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating prolactin level  (IAGP)
increased collagen level  (IAGP)
increased compact bone thickness  (IAGP)
increased endometrial carcinoma incidence  (IAGP)
increased endometrial gland number  (IAGP)
increased granulosa cell tumor incidence  (IAGP)
increased insulin secretion  (IAGP)
increased lung tumor incidence  (IAGP)
increased mature ovarian follicle number  (IAGP)
increased metastatic potential  (IAGP)
increased ovary tumor incidence  (IAGP)
increased pancreatic beta cell number  (IAGP)
increased pancreatic beta cell proliferation  (IAGP)
increased papilloma incidence  (IAGP)
increased reproductive system tumor incidence  (IAGP)
increased trabecular bone thickness  (IAGP)
increased uterus leiomyoma incidence  (IAGP)
increased uterus weight  (IAGP)
internal hemorrhage  (IAGP)
no abnormal phenotype detected  (IAGP)
ovary cysts  (IAGP)
pancreatic islet hyperplasia  (IAGP)
premature death  (IAGP)
reduced female fertility  (IAGP)
thin uterine horn  (IAGP)
twin decidual capsule  (IAGP)
uterus cysts  (IAGP)
uterus hyperplasia  (IAGP)
uterus inflammation  (IAGP)
vascular smooth muscle hyperplasia  (IAGP)
References

Additional References at PubMed
PMID:1679745   PMID:2069958   PMID:2190799   PMID:7476982   PMID:7557380   PMID:7802637   PMID:7819129   PMID:8415723   PMID:8603049   PMID:8742817   PMID:8978696   PMID:9171243  
PMID:9178755   PMID:9275084   PMID:9322923   PMID:9435255   PMID:9459191   PMID:9560231   PMID:9878278   PMID:9878774   PMID:9890981   PMID:10208978   PMID:10349636   PMID:10433223  
PMID:10552042   PMID:10582092   PMID:10707954   PMID:10732326   PMID:10733525   PMID:10781075   PMID:10894157   PMID:10976068   PMID:11042159   PMID:11070092   PMID:11076861   PMID:11130978  
PMID:11217851   PMID:11313721   PMID:11518735   PMID:11564713   PMID:11897499   PMID:12058073   PMID:12392693   PMID:12403837   PMID:12438645   PMID:12456789   PMID:12477932   PMID:12601162  
PMID:12648519   PMID:12663498   PMID:12672823   PMID:12724519   PMID:12826701   PMID:12890938   PMID:12897242   PMID:12937679   PMID:14500579   PMID:14635795   PMID:14667967   PMID:14667968  
PMID:14667970   PMID:14681235   PMID:14688261   PMID:14744870   PMID:14765981   PMID:14973394   PMID:15044369   PMID:15117941   PMID:15256533   PMID:15329476   PMID:15374713   PMID:15617723  
PMID:15618518   PMID:15680344   PMID:15682389   PMID:15817149   PMID:15845616   PMID:15878961   PMID:16002522   PMID:16135805   PMID:16141072   PMID:16141073   PMID:16176985   PMID:16223481  
PMID:16339279   PMID:16413068   PMID:16439483   PMID:16457691   PMID:16466956   PMID:16484336   PMID:16543407   PMID:16602821   PMID:16728408   PMID:16868919   PMID:16914740   PMID:16951680  
PMID:16973758   PMID:17021053   PMID:17045797   PMID:17101553   PMID:17149722   PMID:17170211   PMID:17205580   PMID:17242168   PMID:17276340   PMID:17317767   PMID:17341305   PMID:17546050  
PMID:17574608   PMID:17590085   PMID:17595323   PMID:17881490   PMID:17941046   PMID:17986609   PMID:18026113   PMID:18079204   PMID:18172011   PMID:18239353   PMID:18276762   PMID:18287559  
PMID:18287572   PMID:18305227   PMID:18321550   PMID:18514427   PMID:18546535   PMID:18599509   PMID:18632614   PMID:18806829   PMID:19036901   PMID:19103753   PMID:19325003   PMID:19357364  
PMID:19372202   PMID:19383543   PMID:19423765   PMID:19429458   PMID:19439667   PMID:19487454   PMID:19551522   PMID:19679546   PMID:19715581   PMID:19797400   PMID:19913568   PMID:20018910  
PMID:20029965   PMID:20051488   PMID:20056671   PMID:20117174   PMID:20124728   PMID:20130264   PMID:20133621   PMID:20219888   PMID:20375256   PMID:20382891   PMID:20404095   PMID:20418913  
PMID:20440553   PMID:20484741   PMID:20506473   PMID:20550710   PMID:20605949   PMID:20625385   PMID:20670676   PMID:20713718   PMID:20804775   PMID:20829392   PMID:20876300   PMID:20932939  
PMID:20962251   PMID:21093581   PMID:21163582   PMID:21184768   PMID:21209023   PMID:21228174   PMID:21238538   PMID:21267068   PMID:21330545   PMID:21371703   PMID:21464042   PMID:21508348  
PMID:21527503   PMID:21570712   PMID:21613631   PMID:21653731   PMID:21677750   PMID:21680703   PMID:21818351   PMID:21828184   PMID:21862609   PMID:21868453   PMID:21873635   PMID:21990372  
PMID:22025690   PMID:22100262   PMID:22155565   PMID:22202164   PMID:22233806   PMID:22294749   PMID:22367588   PMID:22378759   PMID:22378764   PMID:22383889   PMID:22396492   PMID:22416080  
PMID:22529366   PMID:22585830   PMID:22588720   PMID:22635678   PMID:22638070   PMID:22706342   PMID:22740122   PMID:22759378   PMID:22798293   PMID:22933106   PMID:22988430   PMID:23079602  
PMID:23103586   PMID:23288720   PMID:23307939   PMID:23462470   PMID:23475984   PMID:23531596   PMID:23536368   PMID:23663785   PMID:23676498   PMID:23740945   PMID:23741500   PMID:23784889  
PMID:23810007   PMID:23817023   PMID:23820898   PMID:23827354   PMID:23867473   PMID:23880761   PMID:23885093   PMID:23979163   PMID:23979845   PMID:23983142   PMID:23999864   PMID:24012679  
PMID:24014651   PMID:24025729   PMID:24190884   PMID:24204309   PMID:24227756   PMID:24244176   PMID:24265455   PMID:24265601   PMID:24345432   PMID:24469993   PMID:24474556   PMID:24485460  
PMID:24571987   PMID:24603706   PMID:24823394   PMID:24945252   PMID:24945655   PMID:24952961   PMID:24998851   PMID:25043182   PMID:25058027   PMID:25172890   PMID:25261374   PMID:25321413  
PMID:25333515   PMID:25339733   PMID:25377472   PMID:25384213   PMID:25505200   PMID:25603931   PMID:25687138   PMID:25774501   PMID:25882702   PMID:25976672   PMID:26076042   PMID:26107991  
PMID:26184908   PMID:26241389   PMID:26305333   PMID:26305969   PMID:26350477   PMID:26378916   PMID:26411367   PMID:26431032   PMID:26465008   PMID:26484579   PMID:26510866   PMID:26512061  
PMID:26544941   PMID:26598666   PMID:26667042   PMID:26676302   PMID:26678340   PMID:26721398   PMID:26833131   PMID:26858409   PMID:26910913   PMID:26984887   PMID:26996671   PMID:27007157  
PMID:27018534   PMID:27080304   PMID:27102016   PMID:27174800   PMID:27262401   PMID:27309940   PMID:27358915   PMID:27441639   PMID:27454290   PMID:27783953   PMID:27910070   PMID:28005395  
PMID:28049829   PMID:28049832   PMID:28203817   PMID:28324064   PMID:28400616   PMID:28424251   PMID:28498971   PMID:28525591   PMID:28559342   PMID:28569405   PMID:28586424   PMID:28637295  
PMID:28657664   PMID:28694502   PMID:28698625   PMID:28731465   PMID:28754906   PMID:28757304   PMID:28874785   PMID:28986464   PMID:29066530   PMID:29202468   PMID:29242273   PMID:29289536  
PMID:29306553   PMID:29346447   PMID:29361573   PMID:29426931   PMID:29532467   PMID:29546395   PMID:29648668   PMID:29688404   PMID:29741588   PMID:29870755   PMID:29911998   PMID:29934619  
PMID:29972793   PMID:30021163   PMID:30118662   PMID:30142194   PMID:30260703   PMID:30306772   PMID:30328345   PMID:30332301   PMID:30356064   PMID:30452456   PMID:30550590   PMID:30626716  
PMID:30651315   PMID:30655341   PMID:30773264   PMID:30776325   PMID:30988300   PMID:31067461   PMID:31073032   PMID:31125045   PMID:31201420   PMID:31509448   PMID:31597742   PMID:31732107  
PMID:31780662   PMID:31841397   PMID:31863959   PMID:31875883   PMID:31883000   PMID:31901086   PMID:31908002   PMID:31911630   PMID:31982918   PMID:32191914   PMID:32213656   PMID:32294429  
PMID:32302290   PMID:32354741   PMID:32493987   PMID:32513733   PMID:32716083   PMID:32843721   PMID:32902612   PMID:32968170   PMID:33048843   PMID:33099617   PMID:33284968   PMID:33399260  
PMID:33496365   PMID:33706098   PMID:34131963  


Genomics

Comparative Map Data
Pgr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3998,890,017 - 8,968,612 (+)NCBIGRCm39mm39
GRCm39 Ensembl98,899,834 - 8,968,612 (+)Ensembl
GRCm3898,898,900 - 8,968,611 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl98,899,833 - 8,968,611 (+)EnsemblGRCm38mm10GRCm38
MGSCv3798,899,833 - 8,968,611 (+)NCBIGRCm37mm9NCBIm37
MGSCv3698,862,303 - 8,926,995 (+)NCBImm8
Celera96,279,529 - 6,348,253 (+)NCBICelera
Cytogenetic Map9A1NCBI
PGR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11101,029,624 - 101,129,813 (-)EnsemblGRCh38hg38GRCh38
GRCh3811101,029,624 - 101,130,681 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711100,900,355 - 101,000,544 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611100,414,313 - 100,506,465 (-)NCBINCBI36hg18NCBI36
Build 3411100,414,312 - 100,506,465NCBI
Celera1198,069,715 - 98,169,894 (-)NCBI
Cytogenetic Map11q22.1NCBI
HuRef1196,837,449 - 96,937,628 (-)NCBIHuRef
CHM1_111100,783,609 - 100,883,736 (-)NCBICHM1_1
Pgr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.286,073,216 - 6,131,552 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl86,072,673 - 6,131,344 (+)Ensembl
Rnor_6.087,128,656 - 7,187,796 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl87,128,656 - 7,187,796 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.087,113,895 - 7,172,761 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.485,784,717 - 5,845,901 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.185,784,716 - 5,845,901 (+)NCBI
Celera87,609,728 - 7,668,047 (+)NCBICelera
Cytogenetic Map8q11NCBI
Pgr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554124,643,839 - 4,693,478 (-)NCBIChiLan1.0ChiLan1.0
PGR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11199,508,571 - 99,598,020 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01195,997,677 - 96,098,866 (-)NCBIMhudiblu_PPA_v0panPan3
PGR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.121447,197 - 552,511 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl21447,319 - 552,511 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha21461,376 - 566,187 (+)NCBI
ROS_Cfam_1.021609,104 - 717,242 (+)NCBI
UMICH_Zoey_3.121392,996 - 497,928 (+)NCBI
UNSW_CanFamBas_1.021478,480 - 583,792 (+)NCBI
UU_Cfam_GSD_1.021532,736 - 637,643 (+)NCBI
Pgr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494784,948,508 - 85,038,416 (-)NCBI
SpeTri2.0NW_0049365516,498,553 - 6,573,212 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl932,035,684 - 32,129,221 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1932,035,684 - 32,129,776 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2936,044,789 - 36,138,540 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap9p13-p11NCBI
PGR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1192,420,970 - 92,519,128 (-)NCBI
ChlSab1.1 Ensembl192,430,453 - 92,517,296 (-)Ensembl
Vero_WHO_p1.0NW_02366604333,353,079 - 33,447,583 (+)NCBI
Pgr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248781,714,196 - 1,769,302 (+)NCBI

Position Markers
BB114106  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3898,968,456 - 8,968,537UniSTSGRCm38
MGSCv3798,968,456 - 8,968,537UniSTSGRCm37
Celera96,348,098 - 6,348,179UniSTS
Cytogenetic Map9A1UniSTS
Whitehead/MRC_RH973.67UniSTS
PMC18483P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3898,900,447 - 8,900,900UniSTSGRCm38
MGSCv3798,900,447 - 8,900,900UniSTSGRCm37
Celera96,280,143 - 6,280,596UniSTS
Cytogenetic Map9A1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142326Tgq19_mtriglyceride QTL 19 (mouse)Not determined121060750Mouse
1300899Chol6_mcholesterol 6 (mouse)Not determined9129902908Mouse
13434920Dcollq1_mdifferential colonization level QTL 1 (mouse)9130430544Mouse
35673312Ari7_mantibody response to influenza 7, day 45, IgG3 (mouse)9780000022300000Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir181a-2mmu-miR-181a-5pOncomiRDBexternal_infoNANA22492871
Mir181a-1mmu-miR-181a-5pOncomiRDBexternal_infoNANA22492871

Predicted Target Of
Summary Value
Count of predictions:185
Count of miRNA genes:108
Interacting mature miRNAs:120
Transcripts:ENSMUST00000070463, ENSMUST00000098986, ENSMUST00000151080
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000070463   ⟹   ENSMUSP00000063562
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl98,900,469 - 8,965,426 (+)Ensembl
GRCm38.p6 Ensembl98,900,468 - 8,965,425 (+)Ensembl
RefSeq Acc Id: ENSMUST00000098986   ⟹   ENSMUSP00000096584
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl98,900,469 - 8,965,426 (+)Ensembl
GRCm38.p6 Ensembl98,900,468 - 8,965,425 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151080
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl98,900,420 - 8,948,608 (+)Ensembl
GRCm38.p6 Ensembl98,900,419 - 8,948,607 (+)Ensembl
RefSeq Acc Id: ENSMUST00000189181   ⟹   ENSMUSP00000140124
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl98,899,834 - 8,968,612 (+)Ensembl
GRCm38.p6 Ensembl98,899,833 - 8,968,611 (+)Ensembl
RefSeq Acc Id: NM_008829   ⟹   NP_032855
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3998,899,834 - 8,968,612 (+)NCBI
GRCm3898,899,833 - 8,968,611 (+)NCBI
MGSCv3798,899,833 - 8,968,611 (+)RGD
Celera96,279,529 - 6,348,253 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006509848   ⟹   XP_006509911
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3998,890,017 - 8,918,889 (+)NCBI
GRCm3898,898,900 - 8,918,888 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032855   ⟸   NM_008829
- UniProtKB: Q00175 (UniProtKB/Swiss-Prot),   Q8BW69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006509911   ⟸   XM_006509848
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000096584   ⟸   ENSMUST00000098986
RefSeq Acc Id: ENSMUSP00000063562   ⟸   ENSMUST00000070463
RefSeq Acc Id: ENSMUSP00000140124   ⟸   ENSMUST00000189181
Protein Domains
NR LBD   Nuclear receptor

Promoters
RGD ID:8668824
Promoter ID:EPDNEW_M12421
Type:multiple initiation site
Name:Pgr_1
Description:Mus musculus progesterone receptor , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3898,899,834 - 8,899,894EPDNEW
RGD ID:6844932
Promoter ID:MM_KWN:56349
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung
Transcripts:ENSMUST00000098987,   NM_008829,   UC009ODN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3698,900,281 - 8,901,882 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97567 AgrOrtholog
Ensembl Genes ENSMUSG00000031870 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000063562 UniProtKB/Swiss-Prot
  ENSMUSP00000096584 UniProtKB/Swiss-Prot
  ENSMUSP00000140124 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000070463 UniProtKB/Swiss-Prot
  ENSMUST00000098986 UniProtKB/Swiss-Prot
  ENSMUST00000189181 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro NHR-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Progest_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:97567 ENTREZGENE
NCBI Gene 18667 ENTREZGENE
Pfam Hormone_recep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prog_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pgr PhenoGen
PRINTS PROGESTRONER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STRDHORMONER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOLI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48508 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt PRGR_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UQA6_MOUSE UniProtKB/TrEMBL
  Q3UUZ5_MOUSE UniProtKB/TrEMBL
  Q8BW69 ENTREZGENE, UniProtKB/TrEMBL
  Q8BZ29_MOUSE UniProtKB/TrEMBL
UniProt Secondary A6H6A5 UniProtKB/Swiss-Prot
  E9QPW3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 Pgr  progesterone receptor  ENSMUSG00000074510  predicted gene, ENSMUSG00000074510  Data Merged 737654 PROVISIONAL
2016-04-05 Pgr  progesterone receptor  BB114106  expressed sequence BB114106  Data Merged 737654 PROVISIONAL