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Gene: Slc7a11 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 11) Mus musculus
Symbol: Slc7a11
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
Description: ENCODES a protein that exhibits transmembrane transporter activity (inferred); INVOLVED IN adult behavior; brain development; cellular response to oxidative stress; ASSOCIATED WITH abnormal cell death; abnormal circulating amino acid level; abnormal dendritic cell physiology; ASSOCIATED WITH contact dermatitis (ortholog); Neoplasm Metastasis (ortholog); FOUND IN astrocyte projection; brush border membrane; membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol; 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9930009M05Rik; AI451155; amino acid transport system xc-; cysteine/glutamate transporter; cystine/glutamate transporter; sodium independent anionic amino acid transport system; solute carrier family 7 member 11; sut; xCT
Homo sapiens (human) : SLC7A11 (solute carrier family 7 member 11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc7a11 (solute carrier family 7 member 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc7a11 (solute carrier family 7 member 11)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC7A11 (solute carrier family 7 member 11)
Canis lupus familiaris (dog) : SLC7A11 (solute carrier family 7 member 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc7a11 (solute carrier family 7 member 11)
Sus scrofa (pig) : SLC7A11 (solute carrier family 7 member 11)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38350,364,936 - 50,499,087 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37350,168,858 - 50,247,535 (-)NCBIGRCm37mm9NCBIm37
MGSCv36350,461,131 - 50,539,808 (-)NCBImm8
Celera350,149,206 - 50,227,932 (-)NCBICelera
Cytogenetic Map3 CNCBI
cM Map321.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Slc7a11
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319532
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.