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Gene: Helz2 (helicase with zinc finger 2, transcriptional coactivator) Mus musculus
Symbol: Helz2
Name: helicase with zinc finger 2, transcriptional coactivator
Description: Predicted to have RNA binding activity and nuclear receptor transcription coactivator activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay and positive regulation of transcription by RNA polymerase II. Predicted to localize to the cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; respiratory system; and telencephalon. Orthologous to human HELZ2 (helicase with zinc finger 2); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: helicase with zinc finger domain 2; MGC63178; mKIAA1769; mPDIP1; PDIP1; peroxisomal proliferator-activated receptor A interacting complex 285; PPAR gamma-DNA-binding domain interacting protein1; PPAR-gamma DBD-interacting protein 1; PPAR-gamma DNA-binding domain-interacting protein 1; Pric285; RP23-401M24.3
Homo sapiens (human) : HELZ2 (helicase with zinc finger 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Helz2 (helicase with zinc finger 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Helz2 (helicase with zinc finger 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HELZ2 (helicase with zinc finger 2)
Canis lupus familiaris (dog) : HELZ2 (helicase with zinc finger 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Helz2 (helicase with zinc finger 2)
Sus scrofa (pig) : HELZ2 (helicase with zinc finger 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382181,227,615 - 181,242,058 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372180,962,320 - 180,976,732 (-)NCBIGRCm37mm9NCBIm37
MGSCv362181,157,014 - 181,171,434 (-)NCBImm8
Celera2185,310,414 - 185,324,847 (-)NCBICelera
Cytogenetic Map2 H4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Helz2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314454
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.