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Gene: Alox15 (arachidonate 15-lipoxygenase) Mus musculus
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Symbol: Alox15
Name: arachidonate 15-lipoxygenase
Description: Exhibits arachidonate 12-lipoxygenase activity and arachidonate 15-lipoxygenase activity. Involved in several processes, including icosanoid metabolic process; phosphatidylethanolamine biosynthetic process; and regulation of engulfment of apoptotic cell. Localizes to the cytosol and plasma membrane. Is expressed in several structures, including alimentary system; liver; nose; peritoneal fluid; and respiratory system. Orthologous to human ALOX15 (arachidonate 15-lipoxygenase); PARTICIPATES IN atherosclerosis pathway; type 1 diabetes mellitus pathway; acetylsalicylic acid pharmacodynamics pathway; INTERACTS WITH (5Z,8Z,11Z,13E)-15-HETE; 4,4'-sulfonyldiphenol; 6-oxoprostaglandin F1alpha.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 12-LO; 12-LOX; 12/15-lipoxygenase; 12/15-LO; 15-LOX; Alox12l; arachidonate 12-lipoxygenase, leukocyte-type; arachidonate omega-6 lipoxygenase; L-12LO
Orthologs:
Homo sapiens (human) : ALOX15 (arachidonate 15-lipoxygenase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Alox15 (arachidonate 15-lipoxygenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alox15 (arachidonate 15-lipoxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : ALOX15 (arachidonate 15-lipoxygenase)
Canis lupus familiaris (dog) : ALOX15 (arachidonate 15-lipoxygenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alox15 (arachidonate 15-lipoxygenase)
Sus scrofa (pig) : ALOX15 (arachidonate 15-lipoxygenase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381170,344,147 - 70,390,538 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371170,157,649 - 70,165,533 (-)NCBIGRCm37mm9NCBIm37
MGSCv361170,160,348 - 70,168,210 (-)NCBImm8
Celera1177,888,721 - 77,896,673 (-)NCBICelera
Cytogenetic Map11 B3NCBI
cM Map1142.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Alox15
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733626
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.