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Gene: Akap12 (A kinase (PRKA) anchor protein (gravin) 12) Mus musculus
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Symbol: Akap12
Name: A kinase (PRKA) anchor protein (gravin) 12
Description: Predicted to have adenylate cyclase binding activity. Involved in modulation of chemical synaptic transmission. Localizes to the Schaffer collateral - CA1 synapse. Human ortholog(s) of this gene implicated in chronic kidney disease; colorectal carcinoma; and juvenile myelomonocytic leukemia. Is expressed in central nervous system; neural ectoderm; pancreas mesenchyme; and retina. Orthologous to human AKAP12 (A-kinase anchoring protein 12); PARTICIPATES IN protein kinase A (PKA) signaling pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A-kinase anchor protein 12; AI317366; AKAP-12; gercelin; germ cell lineage protein gercelin; src-suppressed C kinase substrate; Srcs5; SSeCKS; testis specific gene A12; Tsga12; v-src suppressed transcript 5
Orthologs:
Homo sapiens (human) : AKAP12 (A-kinase anchoring protein 12)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Akap12 (A-kinase anchoring protein 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akap12 (A-kinase anchoring protein 12)
Pan paniscus (bonobo/pygmy chimpanzee) : AKAP12 (A-kinase anchoring protein 12)
Canis lupus familiaris (dog) : AKAP12 (A-kinase anchoring protein 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akap12 (A-kinase anchoring protein 12)
Sus scrofa (pig) : AKAP12 (A-kinase anchoring protein 12)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38104,266,329 - 4,359,471 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37105,987,070 - 6,080,212 (-)NCBIGRCm37mm9NCBIm37
MGSCv36105,987,070 - 6,080,163 (-)NCBImm8
Celera104,190,840 - 4,288,877 (+)NCBICelera
Cytogenetic Map10 A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Akap12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737244
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.