Ctsl (cathepsin L) - Rat Genome Database

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Gene: Ctsl (cathepsin L) Mus musculus
Symbol: Ctsl
Name: cathepsin L
RGD ID: 10424
Description: Enables cysteine-type carboxypeptidase activity; endopeptidase activity; and histone binding activity. Involved in several processes, including collagen catabolic process; protein catabolic process; and thyroid hormone generation. Acts upstream of or within decidualization; hair follicle morphogenesis; and negative regulation of keratinocyte proliferation. Located in several cellular components, including external side of plasma membrane; lysosome; and nucleolus. Is expressed in several structures, including central nervous system; extraembryonic component; eye; genitourinary system; and hemolymphoid system. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy. Orthologous to several human genes including CTSV (cathepsin V).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 1190035F06Rik; Cat L; cathepsin L1; CatL; Ctsl1; fs; furless; major excreted protein; ME; MEP; nackt; nkt; p39 cysteine proteinase; procathepsin L
RGD Orthologs
Green Monkey
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm17885  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391364,509,704 - 64,518,586 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1364,507,151 - 64,518,704 (-)EnsemblGRCm39 Ensembl
GRCm381364,361,890 - 64,370,772 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1364,359,337 - 64,370,890 (-)EnsemblGRCm38mm10GRCm38
MGSCv371364,464,522 - 64,471,614 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361364,377,945 - 64,385,037 (-)NCBIMGSCv36mm8
Celera1366,025,830 - 66,032,878 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1333.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (EXP)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-tribromophenol  (ISO)
2,4-diaminobutyric acid  (ISO)
2-methoxyethanol  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-methyladenine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-nitrophenol  (EXP)
5-aza-2'-deoxycytidine  (ISO)
aflatoxin B1  (EXP)
albendazole  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
aloxistatin  (ISO)
ammonium chloride  (ISO)
amodiaquine  (ISO)
amphetamine  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
Aroclor 1254  (EXP)
arsenous acid  (ISO)
asperphenamate  (ISO)
azathioprine  (ISO)
Benoxacor  (EXP)
benzo[a]pyrene  (EXP,ISO)
Benzo[k]fluoranthene  (EXP)
beryllium sulfate  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (ISO)
buspirone  (ISO)
butan-1-ol  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP)
calcitriol  (EXP)
carbon nanotube  (EXP)
carmustine  (ISO)
CGP 52608  (ISO)
chloroform  (ISO)
chloroquine  (ISO)
choline  (ISO)
chondroitin sulfate  (ISO)
cimetidine  (ISO)
ciprofibrate  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (ISO)
cyproconazole  (EXP)
cytarabine  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (EXP)
dibutyl phthalate  (EXP,ISO)
dichlorine  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
erythromycin estolate  (ISO)
ethanol  (EXP,ISO)
eugenol  (ISO)
fenamidone  (EXP)
flavonoids  (ISO)
folic acid  (EXP)
fumonisin B1  (EXP)
genistein  (EXP)
gentamycin  (ISO)
glucose  (ISO)
glyphosate  (ISO)
imiquimod  (EXP)
indoles  (ISO)
isoprenaline  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
Liensinine  (EXP)
lipopolysaccharide  (ISO)
maneb  (EXP)
methidathion  (EXP)
methotrexate  (ISO)
methoxyacetic acid  (ISO)
microcystin-LR  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naloxone  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nickel subsulfide  (ISO)
nickel sulfate  (ISO)
nicotine  (EXP)
nimesulide  (ISO)
okadaic acid  (EXP)
oxaliplatin  (ISO)
oxycodone  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
pirimiphos-methyl  (ISO)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
propiconazole  (EXP)
ranitidine  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sevoflurane  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
Soman  (ISO)
sotorasib  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (EXP,ISO)
tamoxifen  (EXP)
tebufenpyrad  (ISO)
teicoplanin  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thapsigargin  (ISO)
theophylline  (ISO)
tioguanine  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trametinib  (ISO)
trichloroethene  (EXP,ISO)
urethane  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adaptive immune response  (ISO)
antigen processing and presentation of peptide antigen  (IMP)
autophagic cell death  (ISO)
CD4-positive, alpha-beta T cell lineage commitment  (IMP)
cell communication  (ISO)
cell communication  (ISO)
cellular response to starvation  (ISO)
cellular response to thyroid hormone stimulus  (ISO)
collagen catabolic process  (IDA)
decidualization  (IGI,ISO)
elastin catabolic process  (IMP)
epithelial tube branching involved in lung morphogenesis  (IMP)
fusion of virus membrane with host endosome membrane  (ISO)
fusion of virus membrane with host plasma membrane  (ISO)
hair follicle morphogenesis  (IMP)
immune response  (IBA)
keratinocyte proliferation  (IMP)
male gonad development  (ISO)
multicellular organism aging  (ISO)
negative regulation of keratinocyte proliferation  (IMP)
nerve development  (ISO)
positive regulation of apoptotic signaling pathway  (IBA)
positive regulation of peptidase activity  (IBA)
protein autoprocessing  (IDA,ISO)
protein catabolic process  (ISO)
protein processing  (IDA,IMP)
proteolysis  (IDA,ISO)
proteolysis involved in protein catabolic process  (IBA,IMP)
receptor-mediated endocytosis of virus by host cell  (ISO)
regulation of actin cytoskeleton organization  (IGI)
response to glucocorticoid  (ISO)
response to glucose  (ISO)
response to gonadotropin  (ISO)
response to odorant  (ISO)
response to organic cyclic compound  (ISO)
Sertoli cell differentiation  (ISO)
spermatogenesis  (ISO)
thyroid hormone generation  (IMP)
viral entry into host cell  (ISO)
zymogen activation  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cardiovascular system physiology  (IAGP)
abnormal cartilage morphology  (IAGP)
abnormal CD4-positive T cell differentiation  (IEA)
abnormal CD8-positive, alpha beta T cell morphology  (IEA)
abnormal CD8-positive, alpha-beta T cell differentiation  (IEA)
abnormal coat appearance  (IAGP)
abnormal coat/ hair morphology  (IAGP)
abnormal epidermis stratum basale morphology  (IAGP)
abnormal external auditory canal morphology  (IAGP)
abnormal hair cycle  (IAGP)
abnormal hair cycle catagen phase  (IAGP)
abnormal hair follicle development  (IAGP)
abnormal hair follicle morphology  (IAGP)
abnormal hair follicle orientation  (IAGP)
abnormal hair growth  (IAGP)
abnormal hair shaft morphology  (IAGP)
abnormal heart echocardiography feature  (IAGP)
abnormal heart electrocardiography waveform feature  (IAGP)
abnormal heartbeat  (IAGP)
abnormal hippocampus pyramidal cell layer  (IAGP)
abnormal immune system organ morphology  (IAGP)
abnormal keratinocyte physiology  (IAGP)
abnormal leukocyte cell number  (IAGP)
abnormal lymph node cortex morphology  (IAGP)
abnormal lymph node morphology  (IAGP)
abnormal lysosome morphology  (IAGP)
abnormal motor coordination/balance  (IAGP)
abnormal myocardial fiber morphology  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal neuron apoptosis  (IAGP)
abnormal osteoclast physiology  (IAGP)
abnormal R wave  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal T cell differentiation  (IEA)
abnormal T wave  (IAGP)
abnormal thymus corticomedullary boundary morphology  (IAGP)
abnormal thymus lobule morphology  (IAGP)
abnormal thymus morphology  (IAGP)
abnormal thyroid follicle morphology  (IAGP)
abnormal thyroid gland morphology  (IAGP)
abnormal thyroid hormone level  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal visceral endoderm morphology  (IAGP)
abnormal visceral yolk sac morphology  (IAGP)
absent vibrissae  (IAGP)
acanthosis  (IAGP)
alopecia  (IAGP)
amyloidosis  (IAGP)
aortic valve regurgitation  (IAGP)
atrioventricular block  (IAGP)
cachexia  (IAGP)
cardiac interstitial fibrosis  (IAGP)
corneal opacity  (IAGP)
decreased alpha-beta T cell number  (IEA)
decreased body size  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased circulating thyroxine level  (IAGP)
decreased long bone epiphyseal plate size  (IAGP)
decreased osteoclast cell number  (IAGP)
decreased susceptibility to autoimmune diabetes  (IAGP)
decreased testis weight  (IAGP)
decreased thyroxine level  (IAGP)
decreased ventricle muscle contractility  (IAGP)
decreased vertical activity  (IAGP)
delayed hair appearance  (IAGP)
dental pulp necrosis  (IAGP)
dermatitis  (IAGP)
dilated cardiomyopathy  (IAGP)
dilated lymph node medullary sinus  (IAGP)
dilated piliary canal  (IAGP)
enlarged heart  (IAGP)
enlarged heart left atrium  (IAGP)
enlarged lymph nodes  (IAGP)
enlarged sebaceous gland  (IAGP)
enlarged thymus cortex  (IAGP)
epidermal hyperplasia  (IAGP)
excessive scratching  (IAGP)
focal dorsal hair loss  (IAGP)
folliculitis  (IAGP)
gliosis  (IAGP)
granulomatous inflammation  (IAGP)
greasy coat  (IAGP)
hair follicle outer root sheath hyperplasia  (IAGP)
heart left ventricle hypertrophy  (IAGP)
hyperglycemia  (IAGP)
hypergranulosis  (IAGP)
hyperkeratosis  (IAGP)
increased alpha-beta T cell number  (IEA)
increased CD8-positive, alpha-beta T cell number  (IAGP)
increased central memory CD4-positive, alpha-beta T cell number  (IEA)
increased central memory CD8 positive, alpha-beta T cell number  (IEA)
increased effector memory CD4-positive, alpha-beta T cell number  (IEA)
increased heart rate  (IAGP)
increased heart weight  (IAGP)
increased inflammatory response  (IAGP)
increased keratinocyte proliferation  (IAGP)
increased regulatory T cell number  (IAGP)
insulitis  (IAGP)
liver inflammation  (IAGP)
lymph node hyperplasia  (IAGP)
lymph node inflammation  (IAGP)
mitral valve regurgitation  (IAGP)
neuron degeneration  (IAGP)
orthokeratosis  (IAGP)
periodontal ligament necrosis  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
Purkinje cell degeneration  (IAGP)
rough coat  (IAGP)
salivary gland inflammation  (IAGP)
scaly skin  (IAGP)
shiny skin  (IAGP)
short hair  (IAGP)
short vibrissae  (IAGP)
skin lesions  (IAGP)
sparse hair  (IAGP)
sparse vibrissae  (IAGP)
thick dermal layer  (IAGP)
thick epidermis  (IAGP)
thick skin  (IAGP)
thymus atrophy  (IAGP)
tremors  (IAGP)
underdeveloped hair follicles  (IAGP)

References - curated
# Reference Title Reference Citation
1. Overexpression of phosphodiesterases in experimental autoimmune myasthenia gravis: suppression of disease by a phosphodiesterase inhibitor. Aricha R, etal., FASEB J. 2006 Feb;20(2):374-6. Epub 2005 Dec 19.
2. Cathepsin S is activated during colitis and causes visceral hyperalgesia by a PAR2-dependent mechanism in mice. Cattaruzza F, etal., Gastroenterology. 2011 Nov;141(5):1864-74.e1-3. Epub 2011 Jul 28.
3. Spinal cathepsin S and fractalkine contribute to chronic pain in collagen induced arthritis. Clark AK, etal., Arthritis Rheum. 2011 Dec 27. doi: 10.1002/art.34351.
4. The protective effect of dexanabinol (HU-211) on nitric oxide and cysteine protease-mediated neuronal death in focal cerebral ischemia. Durmaz R, etal., Neurochem Res. 2008 Sep;33(9):1683-91. Epub 2008 Apr 11.
5. Increased muscle proteolysis after local trauma mainly reflects macrophage-associated lysosomal proteolysis. Farges MC, etal., Am J Physiol Endocrinol Metab 2002 Feb;282(2):E326-35.
6. Hypertension-mediated albuminuria is associated with reduced lysosomal activity in the kidney and the heart. Hilliard LM, etal., Am J Nephrol. 2009;29(5):454-64. Epub 2008 Nov 21.
7. Roles for cathepsins S, L, and B in insulitis and diabetes in the NOD mouse. Hsing LC, etal., J Autoimmun. 2009 Aug 5.
8. Impaired cathepsin L gene expression in skeletal muscle is associated with type 2 diabetes. Huang X, etal., Diabetes. 2003 Sep;52(9):2411-8.
9. Genetic and pharmacologic alteration of cathepsin expression influences reovirus pathogenesis. Johnson EM, etal., J Virol. 2009 Oct;83(19):9630-40. Epub 2009 Jul 29.
10. Differential expression of cysteine and aspartic proteases during progression of atherosclerosis in apolipoprotein E-deficient mice. Jormsjo S, etal., Am J Pathol. 2002 Sep;161(3):939-45.
11. Role for IkappaBalpha, but not c-Rel, in skeletal muscle atrophy. Judge AR, etal., Am J Physiol Cell Physiol. 2007 Jan;292(1):C372-82. Epub 2006 Aug 23.
12. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
13. Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. Lecker SH, etal., FASEB J. 2004 Jan;18(1):39-51.
14. Cathepsin gene expression profile in rat acute pneumococcal otitis media. Li-Korotky HS, etal., Laryngoscope 2004 Jun;114(6):1032-6.
15. Induced expression of cathepsins and cystatin C in a murine model of demyelination. Ma J, etal., Neurochem Res. 2007 Feb;32(2):311-20. Epub 2006 Nov 4.
16. Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis. Mareninova OA, etal., J Clin Invest. 2009 Nov;119(11):3340-55. doi: 10.1172/JCI38674. Epub 2009 Oct 1.
17. Localization of cathepsins G and L in spontaneous resorption of intervertebral discs in a rat experimental model. Meng W, etal., J Musculoskelet Neuronal Interact. 2001 Dec;2(2):171-6.
18. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
19. MGDs mouse GO annotations MGD data from the GO Consortium
21. Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Neidhardt L, etal., Mech Dev 2000 Nov;98(1-2):77-94.
22. Experimental hyperthyroidism in rats increases the expression of the ubiquitin ligases atrogin-1 and MuRF1 and stimulates multiple proteolytic pathways in skeletal muscle. O'Neal P, etal., J Cell Biochem. 2009 Nov 1;108(4):963-73.
23. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
24. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
25. Intrinsic fibroblast-mediated remodeling of damaged collagenous matrices in vivo. Provenzano PP, etal., Matrix Biol. 2005 Jan;23(8):543-55. Epub 2004 Dec 1.
26. Role of chaperone-mediated autophagy in degrading Huntington's disease-associated huntingtin protein. Qi L and Zhang XD, Acta Biochim Biophys Sin (Shanghai). 2014 Feb;46(2):83-91. doi: 10.1093/abbs/gmt133. Epub 2013 Dec 8.
27. Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin. Reiser J, etal., J Biol Chem 2004 Aug 13;279(33):34827-32. Epub 2004 Jun 14.
28. Mouse MP Annotation Import Pipeline RGD automated import pipeline
29. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
30. Effect of vitamin E and human placenta cysteine peptidase inhibitor on expression of cathepsins B and L in implanted hepatoma Morris 5123 tumor model in Wistar rats. Sebzda T, etal., World J Gastroenterol. 2005 Jan 28;11(4):587-92.
31. Endostatin and angiostatin are increased in diabetic patients with coronary artery disease and associated with impaired coronary collateral formation. Sodha NR, etal., Am J Physiol Heart Circ Physiol. 2009 Feb;296(2):H428-34. Epub 2008 Dec 12.
32. Evolution of placentally expressed cathepsins. Sol-Church K, etal., Biochem Biophys Res Commun 2002 Apr 26;293(1):23-9.
33. Mouse cathepsin M, a placenta-specific lysosomal cysteine protease related to cathepsins L and P. Sol-Church K, etal., Biochim Biophys Acta 2000 Apr 25;1491(1-3):289-94.
34. Cathepsin L gene expression and promoter activation in rodent granulosa cells. Sriraman V and Richards JS, Endocrinology 2004 Feb;145(2):582-91. Epub 2003 Oct 16.
35. Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L. Stypmann J, etal., Proc Natl Acad Sci U S A 2002 Apr 30;99(9):6234-9. Epub 2002 Apr 23.
36. Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells. Sukhova GK, etal., J Clin Invest. 1998 Aug 1;102(3):576-83.
37. Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3beta signaling. Tang Q, etal., J Mol Med. 2009 Mar;87(3):249-60. Epub 2008 Dec 19.
Additional References at PubMed
PMID:1482371   PMID:1751032   PMID:2034277   PMID:2275556   PMID:2826441   PMID:2835398   PMID:3533924   PMID:3689328   PMID:3755373   PMID:5563943   PMID:7774911   PMID:8043949  
PMID:8419312   PMID:8554545   PMID:9096102   PMID:9310336   PMID:9507200   PMID:9545226   PMID:10199917   PMID:10349636   PMID:10395917   PMID:10516062   PMID:10600178   PMID:10633857  
PMID:10716919   PMID:10748235   PMID:10922068   PMID:11022031   PMID:11023992   PMID:11042159   PMID:11076861   PMID:11119260   PMID:11398968   PMID:11483509   PMID:11829493   PMID:11830565  
PMID:11884425   PMID:11929604   PMID:11978977   PMID:11986312   PMID:12000732   PMID:12014504   PMID:12021314   PMID:12048238   PMID:12163394   PMID:12186844   PMID:12368909   PMID:12417635  
PMID:12466121   PMID:12477932   PMID:12533435   PMID:12676526   PMID:12775715   PMID:12782676   PMID:12815617   PMID:12867662   PMID:12869695   PMID:12904583   PMID:14681235   PMID:14681479  
PMID:15099520   PMID:15154914   PMID:15308097   PMID:15489334   PMID:15582152   PMID:15665831   PMID:15679121   PMID:15782199   PMID:15831716   PMID:15860733   PMID:15905545   PMID:15905550  
PMID:16079282   PMID:16140986   PMID:16141072   PMID:16141073   PMID:16170054   PMID:16184198   PMID:16314482   PMID:16393949   PMID:16481467   PMID:16508006   PMID:16602821   PMID:16621972  
PMID:16636100   PMID:16705169   PMID:16731916   PMID:16895486   PMID:16939398   PMID:17068745   PMID:17222401   PMID:17404153   PMID:17500053   PMID:17519890   PMID:17622569   PMID:17643114  
PMID:17671649   PMID:17697143   PMID:17765022   PMID:17942402   PMID:18292516   PMID:18362148   PMID:18410501   PMID:18450756   PMID:18469859   PMID:18591414   PMID:18776147   PMID:18829740  
PMID:18849346   PMID:18957203   PMID:19028686   PMID:19589362   PMID:19801522   PMID:19837164   PMID:19900452   PMID:20017393   PMID:20023699   PMID:20075068   PMID:20080943   PMID:20304958  
PMID:20338168   PMID:20428172   PMID:20487527   PMID:20495178   PMID:20497254   PMID:20536383   PMID:20541250   PMID:20562862   PMID:20877570   PMID:21147810   PMID:21251246   PMID:21292981  
PMID:21434350   PMID:21538579   PMID:21750527   PMID:21868704   PMID:21873635   PMID:21911934   PMID:21956111   PMID:21972973   PMID:22126332   PMID:22245096   PMID:22451661   PMID:22668694  
PMID:22916010   PMID:23233448   PMID:23236527   PMID:23315080   PMID:23468951   PMID:23516607   PMID:23585893   PMID:23600672   PMID:23608608   PMID:23811845   PMID:23912553   PMID:24145449  
PMID:24154525   PMID:24164898   PMID:24319737   PMID:24388751   PMID:24902901   PMID:25063677   PMID:25144390   PMID:25222295   PMID:25283994   PMID:25514977   PMID:25927437   PMID:25957406  
PMID:26075905   PMID:26170293   PMID:26343333   PMID:26639231   PMID:26682926   PMID:26693174   PMID:27143361   PMID:27477282   PMID:27575559   PMID:27586811   PMID:27626662   PMID:27716790  
PMID:27997605   PMID:28071719   PMID:28087651   PMID:28332696   PMID:28759565   PMID:28827407   PMID:28835281   PMID:29154036   PMID:29386126   PMID:29909986   PMID:30824970   PMID:30931961  
PMID:31010818   PMID:31096818   PMID:31611307   PMID:31771567   PMID:31932607   PMID:32325033   PMID:32457751   PMID:32707827   PMID:33540247   PMID:33758261   PMID:34445307   PMID:34815802  
PMID:36038449   PMID:36206719  


Comparative Map Data
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391364,509,704 - 64,518,586 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1364,507,151 - 64,518,704 (-)EnsemblGRCm39 Ensembl
GRCm381364,361,890 - 64,370,772 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1364,359,337 - 64,370,890 (-)EnsemblGRCm38mm10GRCm38
MGSCv371364,464,522 - 64,471,614 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361364,377,945 - 64,385,037 (-)NCBIMGSCv36mm8
Celera1366,025,830 - 66,032,878 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1333.26NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38987,726,119 - 87,731,469 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl987,724,051 - 87,731,469 (+)EnsemblGRCh38hg38GRCh38
GRCh37990,341,034 - 90,346,384 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36989,530,794 - 89,536,204 (+)NCBINCBI36Build 36hg18NCBI36
Build 34987,570,533 - 87,575,862NCBI
Celera960,911,195 - 60,916,605 (+)NCBICelera
Cytogenetic Map9q21.33NCBI
HuRef960,165,416 - 60,170,826 (+)NCBIHuRef
CHM1_1990,488,740 - 90,494,151 (+)NCBICHM1_1
T2T-CHM13v2.0999,879,735 - 99,885,089 (+)NCBIT2T-CHM13v2.0
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.217764,370 - 770,533 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl17764,309 - 770,548 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx17783,032 - 789,194 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0172,325,609 - 2,331,773 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.017780,461 - 786,622 (+)NCBIRnor_WKY
Rnor_6.0171,873,105 - 1,879,266 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl171,872,848 - 1,879,279 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0171,861,403 - 1,867,564 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,288,013 - 6,294,174 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1176,288,015 - 6,294,173 (+)NCBI
Celera171,745,833 - 1,751,993 (-)NCBICelera
RH 3.4 Map1716.0RGD
Cytogenetic Map17p14NCBI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.1986,903,001 - 86,908,303 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl986,903,006 - 86,908,303 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0958,851,899 - 58,857,170 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1172,215,774 - 72,219,093 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha172,978,019 - 72,981,188 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0172,520,707 - 72,523,876 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl172,520,707 - 72,523,900 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1172,331,483 - 72,334,652 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0172,097,122 - 72,100,291 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0172,802,852 - 72,806,021 (-)NCBIUU_Cfam_GSD_1.0
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_024404947118,687,401 - 118,693,831 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366803,047,355 - 3,050,640 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl1027,668,264 - 27,674,618 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11027,668,523 - 27,674,705 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21031,907,421 - 31,913,554 (-)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.11298,347,770 - 98,353,426 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1298,347,800 - 98,353,467 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603886,669,582 - 86,675,194 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:230
Count of miRNA genes:196
Interacting mature miRNAs:204
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
10755533Chol18_mcholesterol 18 (mouse)133096946764969467Mouse
10755517Chol15_mcholesterol 15 (mouse)133096946764969467Mouse
12738439Twq4_mtestis weight QTL 4 (mouse)133112911065129110Mouse
14696729Kidlq2_mkidney weight, left QTL 2 (mouse)133134473665344736Mouse
1301299Sluc23_msusceptibility to lung cancer 23 (mouse)Not determined133492194368922081Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133610153070101640Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133610153070101640Mouse
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133614482070144904Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133872035872720517Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133962924973629397Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133962924973629397Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133962924973629397Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134148904275489158Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
26884396Humsd4_mhumerus midshaft diameter 4, 10 week (mouse)134785347673148119Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse
14746975Manh74_mmandible shape 74 (mouse)135247726986477269Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135382078387820897Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135538498089385140Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
1558850Sgp3_mserum gp70 production 3 (mouse)Not determined135647045676971314Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse
10412163Wra1_mwheel running activity 1 (mouse)Not determined135913260093132738Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136425082198250945Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136425082198250945Mouse

Markers in Region
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381364,364,077 - 64,365,302UniSTSGRCm38
MGSCv371364,465,385 - 64,466,610UniSTSGRCm37
Celera1366,026,692 - 66,027,919UniSTS
Cytogenetic Map13B3UniSTS
cM Map1330.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381364,369,188 - 64,370,170UniSTSGRCm38
MGSCv371364,470,496 - 64,471,478UniSTSGRCm37
Celera1366,031,760 - 66,032,742UniSTS
Cytogenetic Map13B3UniSTS
cM Map1330.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381364,363,870 - 64,363,972UniSTSGRCm38
MGSCv371364,465,178 - 64,465,280UniSTSGRCm37
Celera1366,026,485 - 66,026,587UniSTS
Cytogenetic Map13B3UniSTS
cM Map1330.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381364,366,581 - 64,366,990UniSTSGRCm38
MGSCv371364,467,889 - 64,468,298UniSTSGRCm37
Celera1366,029,178 - 66,029,587UniSTS
Cytogenetic Map13B3UniSTS



Nucleotide Sequences
RefSeq Transcripts NM_009984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF121837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF121838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF121839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV023994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ076620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT030159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J02583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L06427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M20495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X04392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X06086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y18465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000021933   ⟹   ENSMUSP00000021933
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1364,511,028 - 64,518,120 (-)Ensembl
GRCm38.p6 Ensembl1364,363,214 - 64,370,306 (-)Ensembl
RefSeq Acc Id: ENSMUST00000220617
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1364,516,686 - 64,518,120 (-)Ensembl
GRCm38.p6 Ensembl1364,368,872 - 64,370,306 (-)Ensembl
RefSeq Acc Id: ENSMUST00000220737   ⟹   ENSMUSP00000152551
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1364,514,813 - 64,518,567 (-)Ensembl
GRCm38.p6 Ensembl1364,366,999 - 64,370,753 (-)Ensembl
RefSeq Acc Id: ENSMUST00000222462   ⟹   ENSMUSP00000152497
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1364,514,293 - 64,518,120 (-)Ensembl
GRCm38.p6 Ensembl1364,366,479 - 64,370,306 (-)Ensembl
RefSeq Acc Id: ENSMUST00000222517   ⟹   ENSMUSP00000152169
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1364,507,151 - 64,518,704 (-)Ensembl
GRCm38.p6 Ensembl1364,359,337 - 64,370,890 (-)Ensembl
RefSeq Acc Id: ENSMUST00000222971   ⟹   ENSMUSP00000152819
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1364,512,906 - 64,514,869 (-)Ensembl
GRCm38.p6 Ensembl1364,365,092 - 64,367,055 (-)Ensembl
RefSeq Acc Id: ENSMUST00000223494   ⟹   ENSMUSP00000152357
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1364,514,688 - 64,518,120 (-)Ensembl
GRCm38.p6 Ensembl1364,366,874 - 64,370,306 (-)Ensembl
RefSeq Acc Id: NM_009984   ⟹   NP_034114
RefSeq Status: REVIEWED
Mouse AssemblyChrPosition (strand)Source
GRCm391364,509,704 - 64,518,334 (-)NCBI
GRCm381364,361,890 - 64,370,520 (-)NCBI
MGSCv371364,464,522 - 64,471,614 (-)RGD
Celera1366,025,830 - 66,032,878 (-)RGD
RefSeq Acc Id: XM_006517080   ⟹   XP_006517143
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm391364,511,610 - 64,518,586 (-)NCBI
GRCm381364,363,796 - 64,370,772 (-)NCBI
Protein Sequences
Protein RefSeqs NP_034114 (Get FASTA)   NCBI Sequence Viewer  
  XP_006517143 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA37445 (Get FASTA)   NCBI Sequence Viewer  
  AAA39984 (Get FASTA)   NCBI Sequence Viewer  
  AAD32136 (Get FASTA)   NCBI Sequence Viewer  
  AAD32137 (Get FASTA)   NCBI Sequence Viewer  
  AAD32138 (Get FASTA)   NCBI Sequence Viewer  
  AAH68163 (Get FASTA)   NCBI Sequence Viewer  
  BAB21945 (Get FASTA)   NCBI Sequence Viewer  
  BAB27719 (Get FASTA)   NCBI Sequence Viewer  
  BAC33761 (Get FASTA)   NCBI Sequence Viewer  
  BAE22939 (Get FASTA)   NCBI Sequence Viewer  
  BAE26206 (Get FASTA)   NCBI Sequence Viewer  
  BAE27712 (Get FASTA)   NCBI Sequence Viewer  
  BAE29572 (Get FASTA)   NCBI Sequence Viewer  
  BAE30172 (Get FASTA)   NCBI Sequence Viewer  
  BAE31701 (Get FASTA)   NCBI Sequence Viewer  
  BAE31977 (Get FASTA)   NCBI Sequence Viewer  
  BAE35143 (Get FASTA)   NCBI Sequence Viewer  
  BAE35627 (Get FASTA)   NCBI Sequence Viewer  
  BAE36450 (Get FASTA)   NCBI Sequence Viewer  
  BAE38161 (Get FASTA)   NCBI Sequence Viewer  
  BAE41141 (Get FASTA)   NCBI Sequence Viewer  
  BAE41323 (Get FASTA)   NCBI Sequence Viewer  
  CAA27980 (Get FASTA)   NCBI Sequence Viewer  
  CAA29470 (Get FASTA)   NCBI Sequence Viewer  
  CAA77183 (Get FASTA)   NCBI Sequence Viewer  
  EDL16242 (Get FASTA)   NCBI Sequence Viewer  
  P06797 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_034114   ⟸   NM_009984
- Peptide Label: preproprotein
- UniProtKB: Q91UZ0 (UniProtKB/Swiss-Prot),   P06797 (UniProtKB/Swiss-Prot),   Q543M3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517143   ⟸   XM_006517080
- Peptide Label: isoform X1
- UniProtKB: Q91UZ0 (UniProtKB/Swiss-Prot),   P06797 (UniProtKB/Swiss-Prot),   Q543M3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000152357   ⟸   ENSMUST00000223494
RefSeq Acc Id: ENSMUSP00000152819   ⟸   ENSMUST00000222971
RefSeq Acc Id: ENSMUSP00000152497   ⟸   ENSMUST00000222462
RefSeq Acc Id: ENSMUSP00000152169   ⟸   ENSMUST00000222517
RefSeq Acc Id: ENSMUSP00000021933   ⟸   ENSMUST00000021933
RefSeq Acc Id: ENSMUSP00000152551   ⟸   ENSMUST00000220737
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P06797-F1-model_v2 AlphaFold P06797 1-334 view protein structure

RGD ID:8680650
Promoter ID:EPDNEW_M18355
Type:initiation region
Description:Mus musculus cathepsin L , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Mouse AssemblyChrPosition (strand)Source
GRCm381364,370,306 - 64,370,366EPDNEW
RGD ID:6847029
Promoter ID:MM_ACW:13632
SO ACC ID:SO:0000170
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   MEF_B6
Mouse AssemblyChrPosition (strand)Source
MGSCv361364,465,131 - 64,465,631 (-)MPROMDB
RGD ID:6823791
Promoter ID:MM_KWN:14476
SO ACC ID:SO:0000170
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Mouse AssemblyChrPosition (strand)Source
MGSCv361364,471,466 - 64,471,966 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88564 AgrOrtholog
Ensembl Genes ENSMUSG00000021477 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000021933 ENTREZGENE
  ENSMUSP00000021933.8 UniProtKB/Swiss-Prot
  ENSMUSP00000152169.2 UniProtKB/Swiss-Prot
  ENSMUSP00000152357.2 UniProtKB/TrEMBL
  ENSMUSP00000152497.2 UniProtKB/TrEMBL
  ENSMUSP00000152551.2 UniProtKB/TrEMBL
  ENSMUSP00000152819.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000021933 ENTREZGENE
  ENSMUST00000021933.8 UniProtKB/Swiss-Prot
  ENSMUST00000220737.2 UniProtKB/TrEMBL
  ENSMUST00000222462.2 UniProtKB/TrEMBL
  ENSMUST00000222517.2 UniProtKB/Swiss-Prot
  ENSMUST00000222971.2 UniProtKB/TrEMBL
  ENSMUST00000223494.2 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_asp_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_cys_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_his_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C1A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C1A_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C1A_papain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_inhib_I29 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13039 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Inhibitor_I29 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ctsl PhenoGen
SMART Inhibitor_I29 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_C1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54001 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Secondary Q91UZ0 UniProtKB/Swiss-Prot