Pparg (peroxisome proliferator activated receptor gamma) - Rat Genome Database

Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Pparg (peroxisome proliferator activated receptor gamma) Mus musculus
Symbol: Pparg
Name: peroxisome proliferator activated receptor gamma
RGD ID: 69169
Description: Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and arachidonic acid binding activity. Involved in several processes, including cellular response to platelet-derived growth factor stimulus; negative regulation of microglial cell activation; and regulation of transcription by RNA polymerase II. Acts upstream of or within with a negative effect on wound healing involved in inflammatory response. Acts upstream of or within several processes, including brown fat cell differentiation; cellular response to lithium ion; and regulation of gene expression. Located in cytosol and nucleus. Part of SUMO ligase complex. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; musculoskeletal system; and nervous system. Used to study abdominal obesity-metabolic syndrome; congenital generalized lipodystrophy type 2; familial partial lipodystrophy; primary pulmonary hypertension; and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in several diseases, including cardiovascular system disease (multiple); end stage renal disease; lipodystrophy (multiple); obesity; and type 2 diabetes mellitus. Orthologous to human PPARG (peroxisome proliferator activated receptor gamma).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Nr1; Nr1c3; nuclear receptor subfamily 1 group C member 3; peroxisome proliferator activated receptor gamma 2; peroxisome proliferator activated receptor gamma 4; peroxisome proliferator-activated receptor gamma; PPA; PPAR; Ppar-; PPAR-gamma; PPAR-gamma2; PPARgamma; PPARgamma2
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm396115,337,828 - 115,467,365 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6115,337,912 - 115,467,360 (+)EnsemblGRCm39 Ensembl
GRCm386115,360,879 - 115,490,404 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6115,360,951 - 115,490,399 (+)EnsemblGRCm38mm10GRCm38
MGSCv376115,311,239 - 115,440,419 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366115,387,692 - 115,456,020 (+)NCBIMGSCv36mm8
Celera6117,199,637 - 117,329,691 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map653.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)