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Gene: Pparg (peroxisome proliferator activated receptor gamma) Mus musculus
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Symbol: Pparg
Name: peroxisome proliferator activated receptor gamma
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; E-box binding activity; and arachidonic acid binding activity. Predicted to contribute to sequence-specific DNA binding activity. Involved in several processes, including brown fat cell differentiation; cellular response to lithium ion; and regulation of transcription by RNA polymerase II. Localizes to the cytosol and nucleus. Used to study abdominal obesity-metabolic syndrome; congenital generalized lipodystrophy type 2; familial partial lipodystrophy; primary pulmonary hypertension; and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in several diseases, including cardiovascular system disease (multiple); end stage renal failure; familial combined hyperlipidemia; lipodystrophy (multiple); and obesity. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; musculoskeletal system; and nervous system. Orthologous to human PPARG (peroxisome proliferator activated receptor gamma).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Nr1c3; nuclear receptor subfamily 1 group C member 3; peroxisome proliferator activated receptor gamma 2; peroxisome proliferator activated receptor gamma 4; peroxisome proliferator-activated receptor gamma; PPAR-gamma; PPAR-gamma2; PPARgamma; PPARgamma2
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl6115,360,951 - 115,490,399 (+)Ensembl
GRCm386115,360,879 - 115,490,404 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376115,311,239 - 115,440,419 (+)NCBIGRCm37mm9NCBIm37
MGSCv366115,387,692 - 115,456,020 (+)NCBImm8
Celera6117,199,637 - 117,329,691 (+)NCBICelera
Cytogenetic Map6 E3NCBI
cM Map653.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model