Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Plcb4 (phospholipase C, beta 4) Mus musculus
Analyze
Symbol: Plcb4
Name: phospholipase C, beta 4
Description: Predicted to have mitogen-activated protein kinase binding activity and phosphatidylinositol phospholipase C activity. Involved in modulation of chemical synaptic transmission. Localizes to several cellular components, including glutamatergic synapse; parallel fiber to Purkinje cell synapse; and smooth endoplasmic reticulum. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PLCB4 (phospholipase C beta 4); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; protein kinase C (PKC) signaling pathway; Alzheimer's disease pathway; INTERACTS WITH (+)-pilocarpine; 1,2-dichloroethane; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4; A930039J07Rik; AI854601; C230058B11Rik
Orthologs:
Homo sapiens (human) : PLCB4 (phospholipase C beta 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Plcb4 (phospholipase C, beta 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcb4 (phospholipase C beta 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCB4 (phospholipase C beta 4)
Canis lupus familiaris (dog) : PLCB4 (phospholipase C beta 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcb4 (phospholipase C beta 4)
Sus scrofa (pig) : PLCB4 (phospholipase C beta 4)
Chlorocebus sabaeus (African green monkey) : PLCB4 (phospholipase C beta 4)
Heterocephalus glaber (naked mole-rat) : Plcb4 (phospholipase C beta 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl2135,659,011 - 136,014,593 (+)EnsemblGRCm38mm10GRCm38
GRCm382135,658,603 - 136,014,602 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372135,567,566 - 135,838,804 (+)NCBIGRCm37mm9NCBIm37
MGSCv362135,433,271 - 135,704,509 (+)NCBImm8
Celera2136,939,191 - 137,211,347 (+)NCBICelera
Cytogenetic Map2F3NCBI
cM Map266.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Plcb4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11120
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.