Klf10 (Kruppel-like transcription factor 10) - Rat Genome Database

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Gene: Klf10 (Kruppel-like transcription factor 10) Mus musculus
Analyze
Symbol: Klf10
Name: Kruppel-like transcription factor 10
RGD ID: 1551756
MGI Page MGI
Description: Enables core promoter sequence-specific DNA binding activity. Involved in cellular response to starvation; circadian rhythm; and negative regulation of DNA-templated transcription. Acts upstream of or within several processes, including bone mineralization; positive regulation of osteoclast differentiation; and somatic stem cell population maintenance. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; humerus; and trunk unsegmented mesenchyme. Orthologous to human KLF10 (KLF transcription factor 10).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI115143; early growth response, alpha-like; Eg; EGR[a]; Egral; Gdnf; GDNF-inducible factor; Gdnfif; Krueppel-like factor 10; Kruppel-like factor 10; mGI; mGIF; TGFB inducible early growth response 1; TGFB-inducible early growth response protein 1; Tieg; TIEG-1; Tieg1; transcription factor GIF; transforming growth factor-beta-inducible early growth response protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391538,291,702 - 38,300,950 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1538,291,707 - 38,300,950 (-)EnsemblGRCm39 Ensembl
GRCm381538,291,464 - 38,300,711 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1538,291,463 - 38,300,706 (-)EnsemblGRCm38mm10GRCm38
MGSCv371538,224,168 - 38,230,462 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361538,239,002 - 38,245,296 (-)NCBIMGSCv36mm8
Celera1538,920,503 - 38,926,796 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1515.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (EXP)
(S)-nicotine  (EXP)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
15-acetyldeoxynivalenol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3'-diindolylmethane  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
5-aza-2'-deoxycytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
acrylamide  (EXP,ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP)
aldehydo-D-glucosamine  (EXP)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
atrazine  (ISO)
avobenzone  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
beta-D-glucosamine  (EXP)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bromobenzene  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chlordecone  (EXP)
chloroprene  (EXP)
chlorpyrifos  (ISO)
chromium atom  (ISO)
ciguatoxin CTX1B  (EXP)
Cinobufagin  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP,ISO)
decabromodiphenyl ether  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (EXP)
dicrotophos  (ISO)
dieldrin  (ISO)
diethyl maleate  (EXP,ISO)
dioxygen  (EXP)
disulfiram  (ISO)
diuron  (ISO)
doxazosin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
fenofibrate  (EXP,ISO)
fluoranthene  (EXP)
fluoxetine  (ISO)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (ISO)
glucose  (EXP,ISO)
glycine betaine  (ISO)
glyphosate  (ISO)
graphene oxide  (EXP)
hydrazine  (EXP)
hydrogen peroxide  (ISO)
imidacloprid  (ISO)
inulin  (EXP)
iron dichloride  (ISO)
kainic acid  (EXP)
leflunomide  (ISO)
menadione  (ISO)
methamphetamine  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
Monobutylphthalate  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP)
nickel dichloride  (ISO)
nicotine  (EXP)
orphenadrine  (ISO)
paracetamol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenobarbital  (EXP,ISO)
phenol  (ISO)
PhIP  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (EXP,ISO)
raloxifene  (ISO)
ritodrine  (EXP)
rotenone  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
tamoxifen  (EXP)
tert-butyl hydroperoxide  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP)
thiabendazole  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
valsartan  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7518916   PMID:8584037   PMID:9348334   PMID:9745041   PMID:10349636   PMID:10391928   PMID:11042159   PMID:11076861   PMID:12477932   PMID:15489334   PMID:15657444   PMID:15820306  
PMID:16101586   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16615911   PMID:16794021   PMID:16876494   PMID:16888812   PMID:17095659   PMID:17659279   PMID:17951258   PMID:17967808  
PMID:18278048   PMID:18287559   PMID:18396127   PMID:18799693   PMID:19379700   PMID:19602726   PMID:20059953   PMID:20059964   PMID:20070857   PMID:20171187   PMID:20201061   PMID:20378701  
PMID:20385766   PMID:20412781   PMID:20945337   PMID:21267068   PMID:21423731   PMID:21471442   PMID:21491433   PMID:21559363   PMID:21620830   PMID:21731673   PMID:21828131   PMID:21873635  
PMID:22025675   PMID:22121306   PMID:22234868   PMID:22349513   PMID:22380689   PMID:22896699   PMID:23065757   PMID:23178857   PMID:23340137   PMID:23685559   PMID:23707674   PMID:23994618  
PMID:24190163   PMID:24583261   PMID:24944246   PMID:24986741   PMID:25448845   PMID:25456500   PMID:25472963   PMID:25682863   PMID:26310138   PMID:26472224   PMID:26801561   PMID:27421714  
PMID:27428650   PMID:27488034   PMID:27592451   PMID:27736981   PMID:27743478   PMID:28201653   PMID:28204828   PMID:28249899   PMID:28581520   PMID:28836014   PMID:29458012   PMID:29541070  
PMID:29911993   PMID:29930344   PMID:30026232   PMID:30246479   PMID:30948420   PMID:31118478   PMID:31560161   PMID:31975377   PMID:32144802   PMID:32156482   PMID:32738388   PMID:33378664  
PMID:33396939   PMID:33555508   PMID:34402428   PMID:34486132   PMID:35440172   PMID:35492028   PMID:35565995   PMID:35640597   PMID:35726707   PMID:36174463   PMID:36762637   PMID:36968078  
PMID:37308977   PMID:37321514   PMID:37585460   PMID:37628783   PMID:37946098   PMID:38096609   PMID:38217021  


Genomics

Comparative Map Data
Klf10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391538,291,702 - 38,300,950 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1538,291,707 - 38,300,950 (-)EnsemblGRCm39 Ensembl
GRCm381538,291,464 - 38,300,711 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1538,291,463 - 38,300,706 (-)EnsemblGRCm38mm10GRCm38
MGSCv371538,224,168 - 38,230,462 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361538,239,002 - 38,245,296 (-)NCBIMGSCv36mm8
Celera1538,920,503 - 38,926,796 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1515.15NCBI
KLF10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388102,648,784 - 102,655,725 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8102,648,784 - 102,655,725 (-)EnsemblGRCh38hg38GRCh38
GRCh378103,661,012 - 103,667,953 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368103,730,188 - 103,737,128 (-)NCBINCBI36Build 36hg18NCBI36
Build 348103,730,196 - 103,737,128NCBI
Celera899,848,329 - 99,855,302 (-)NCBICelera
Cytogenetic Map8q22.3NCBI
HuRef898,862,246 - 98,869,150 (-)NCBIHuRef
CHM1_18103,701,211 - 103,708,326 (-)NCBICHM1_1
T2T-CHM13v2.08103,777,028 - 103,783,970 (-)NCBIT2T-CHM13v2.0
Klf10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8771,352,612 - 71,358,680 (-)NCBIGRCr8
mRatBN7.2769,467,658 - 69,473,726 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl769,465,619 - 69,473,994 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx771,347,410 - 71,353,478 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0773,549,944 - 73,556,012 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0773,417,968 - 73,424,036 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0777,156,010 - 77,162,096 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl777,156,006 - 77,162,148 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0777,258,859 - 77,265,053 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4773,821,190 - 73,826,866 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1773,842,010 - 73,847,864 (-)NCBI
Celera766,529,946 - 66,535,877 (-)NCBICelera
RH 3.4 Map7631.6RGD
Cytogenetic Map7q22NCBI
Klf10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541727,164,839 - 27,168,604 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541727,165,146 - 27,168,604 (-)NCBIChiLan1.0ChiLan1.0
KLF10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27120,013,188 - 120,020,500 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1895,549,150 - 95,556,311 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0899,302,943 - 99,310,099 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18101,462,915 - 101,469,965 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8101,462,915 - 101,469,982 (-)Ensemblpanpan1.1panPan2
KLF10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1134,216,745 - 4,223,708 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl134,218,084 - 4,223,691 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha134,218,182 - 4,224,873 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0134,376,923 - 4,383,610 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl134,376,925 - 4,383,607 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1134,219,256 - 4,225,960 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0134,336,504 - 4,343,201 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0134,349,283 - 4,355,987 (-)NCBIUU_Cfam_GSD_1.0
Klf10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530333,554,546 - 33,560,778 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647040,980,487 - 40,986,885 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647040,980,487 - 40,986,880 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLF10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl434,429,941 - 34,436,004 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1434,430,132 - 34,435,990 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2437,443,363 - 37,449,221 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KLF10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1897,496,695 - 97,503,818 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl897,496,678 - 97,503,620 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603943,100,548 - 43,107,671 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klf10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476319,581,730 - 19,587,730 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476319,582,019 - 19,592,447 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Klf10
183 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:380
Count of miRNA genes:313
Interacting mature miRNAs:339
Transcripts:ENSMUST00000074043
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401902Sicd2_mseizure-induced cell death 2 (mouse)Not determined15347438971197538Mouse
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
11252136Modvl4_mmodifier of vacuolated lens (mouse)15562049439620614Mouse
26884384Skwq12_mskull length QTL 12, 16 week (mouse)15612948150763396Mouse
26884387Skwq8_mskull length QTL 8, 10 week (mouse)15612948168271849Mouse
26884412Bzwq10_mbi-zygomatic width QTL 10, 10 week (mouse)15612948171471849Mouse
26884417Bzwq4_mbi-zygomatic width QTL 4, 5 week (mouse)15612948172471849Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15612948175871849Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15612948176384200Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
26884429Zlq6_mzygomatic length QTL 6, 10 week (mouse)15682948144963396Mouse
27226721Tibw8_mtibia width 8, proximal, 16 week (mouse)15692948175871849Mouse
27226773Tibl16_mtibia length 16, 10 week (mouse)15692948175871849Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
27095940Ulnl8_mulna length 8, 10 week (mouse)15722948155263396Mouse
27226759Feml17_mfemur length 17, 10 week (mouse)15762948155263396Mouse
27226755Feml22_mfemur length 22, 16 week (mouse)15762948159271849Mouse
27095922Pglq11_mpelvic girdle length QTL 11, 10 week (mouse)15812948438763395Mouse
26884439Sklq11_mskull length QTL 11, 10 week (mouse)15812948447663396Mouse
10412172Habiir5_mhyperoxic acute lung injury imprinted region 5 (mouse)Not determined15927302243311880Mouse
4140994Shali3_msurvival time to hyperoxic acute lung injury 3 (mouse)Not determined927302243311880Mouse
4141192Ssrq2_mstress response QTL 2 (mouse)Not determined927302256186850Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927302279474762Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
1301020Pheo_mpheomelanin (mouse)Not determined151384700647847148Mouse
1302165Yv_myellow value (mouse)Not determined151384700647847148Mouse
4141423Nstr2_mnerve sheath tumor resistance QTL 2 (mouse)Not determined1492758748927756Mouse
1301951Eila3_methanol induced locomotor activity 3 (mouse)Not determined151492758748927756Mouse
1302007Bbaa14_mB.burgdorferi-associated arthritis 14 (mouse)Not determined151492758748927756Mouse
1301499Bdln2_mbody length 2 (mouse)Not determined151564534349645470Mouse
12859288Criq1_mCitrobacter rodentium infection QTL 1 (mouse)151603395450033954Mouse
26884423Zlq10_mzygomatic length QTL 10, 16 week (mouse)152060008650763396Mouse
14928313Manh78_mmandible shape 78 (mouse)152148464155484641Mouse
12859289Criq3_mCitrobacter rodentium infection QTL 3 (mouse)152259376556593765Mouse
4142160Femwf10_mfemur work to failure 10 (mouse)Not determined2289301456893160Mouse
1301557Bbaa22_mB.burgdorferi-associated arthritis 22 (mouse)Not determined152446257258462805Mouse
1300967Bdt6_mbone density traits 6 (mouse)Not determined152529580659295928Mouse
4141409Radsvq1_mradiation sensitivity QTL 1 (mouse)Not determined2548497859484978Mouse
1300772Bglq16_mbody growth late QTL 16 (mouse)Not determined152631178060311880Mouse
1301345Bgeq14_mbody growth early QTL 14 (mouse)Not determined152631178060311880Mouse
1357514Mbis3_mMycobacterium bovis-induced systemic lupus erythematosus 3 (mouse)Not determined162631178060311880Mouse
1301406Egrd2_mearly growth rate (mouse)Not determined152631178060311880Mouse
27226800Scvln20_msacral vertebrae length 2, 16 week (mouse)152660008666371849Mouse
1301450Bpq6_mblood pressure QTL 6 (mouse)Not determined152828264662282739Mouse
1357512Bsbob5_mBSB obesity 5 (mouse)Not determined152828264662282739Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
26884392Humsd8_mhumerus midshaft diameter 8, 16 week (mouse)152930014676084200Mouse
26884452Sklq17_mskull length QTL 17, 16 week (mouse)153020014657963396Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
1300578Cd8ts3_mCD8 T cell subset 3 (mouse)Not determined153400469468004804Mouse
12904003Opfaq12_mopen field activity QTL 12 (mouse)153435891138447901Mouse
1301324Cdif_mcolor difference (mouse)Not determined153597590669976019Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
12792977Tbmd1_mtibial bone mineral density 1, males only (mouse)153807048952031841Mouse

Markers in Region
AI115143  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381538,294,574 - 38,294,719UniSTSGRCm38
MGSCv371538,224,329 - 38,224,474UniSTSGRCm37
Celera1538,920,664 - 38,920,809UniSTS
Cytogenetic Map15B3.1UniSTS
Whitehead/MRC_RH15390.18UniSTS
UniSTS:224865  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381538,294,571 - 38,294,723UniSTSGRCm38
MGSCv371538,224,326 - 38,224,478UniSTSGRCm37
Celera1538,920,661 - 38,920,813UniSTS
Cytogenetic Map15B3.1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001289471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC122459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF049879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF049880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF064088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY548635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S71560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z36270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000074043   ⟹   ENSMUSP00000073690
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1538,294,657 - 38,300,950 (-)Ensembl
GRCm38.p6 Ensembl1538,294,413 - 38,300,706 (-)Ensembl
RefSeq Acc Id: ENSMUST00000226363   ⟹   ENSMUSP00000154702
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1538,294,660 - 38,299,326 (-)Ensembl
GRCm38.p6 Ensembl1538,294,416 - 38,299,082 (-)Ensembl
RefSeq Acc Id: ENSMUST00000227920   ⟹   ENSMUSP00000154265
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1538,291,707 - 38,300,950 (-)Ensembl
GRCm38.p6 Ensembl1538,291,463 - 38,300,706 (-)Ensembl
RefSeq Acc Id: ENSMUST00000228416   ⟹   ENSMUSP00000154669
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1538,300,118 - 38,300,950 (-)Ensembl
GRCm38.p6 Ensembl1538,299,874 - 38,300,706 (-)Ensembl
RefSeq Acc Id: ENSMUST00000228732   ⟹   ENSMUSP00000153975
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1538,297,539 - 38,299,083 (-)Ensembl
GRCm38.p6 Ensembl1538,297,295 - 38,298,839 (-)Ensembl
RefSeq Acc Id: ENSMUST00000228772   ⟹   ENSMUSP00000154055
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1538,297,572 - 38,300,039 (-)Ensembl
GRCm38.p6 Ensembl1538,297,328 - 38,299,795 (-)Ensembl
RefSeq Acc Id: NM_001289471   ⟹   NP_001276400
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391538,291,702 - 38,300,950 (-)NCBI
GRCm381538,291,464 - 38,300,711 (-)NCBI
Celera1538,917,554 - 38,926,800 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001357677   ⟹   NP_001344606
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391538,294,657 - 38,300,950 (-)NCBI
GRCm381538,294,406 - 38,299,900 (-)NCBI
Sequence:
RefSeq Acc Id: NM_013692   ⟹   NP_038720
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391538,294,657 - 38,300,950 (-)NCBI
GRCm381538,294,406 - 38,300,711 (-)NCBI
MGSCv371538,224,168 - 38,230,462 (-)RGD
Celera1538,917,554 - 38,926,800 (-)NCBI
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_038720   ⟸   NM_013692
- Peptide Label: isoform 1
- UniProtKB: O89091 (UniProtKB/Swiss-Prot),   Q3U3K0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001276400   ⟸   NM_001289471
- Peptide Label: isoform 2
- UniProtKB: Q8C900 (UniProtKB/TrEMBL),   Q3U3K0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001344606   ⟸   NM_001357677
- Peptide Label: isoform 3
- UniProtKB: Q9QX13 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000073690   ⟸   ENSMUST00000074043
RefSeq Acc Id: ENSMUSP00000154265   ⟸   ENSMUST00000227920
RefSeq Acc Id: ENSMUSP00000154702   ⟸   ENSMUST00000226363
RefSeq Acc Id: ENSMUSP00000154669   ⟸   ENSMUST00000228416
RefSeq Acc Id: ENSMUSP00000154055   ⟸   ENSMUST00000228772
RefSeq Acc Id: ENSMUSP00000153975   ⟸   ENSMUST00000228732
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O89091-F1-model_v2 AlphaFold O89091 1-479 view protein structure

Promoters
RGD ID:6847207
Promoter ID:MM_ACW:17865
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:KLF10.ASEP07,   KLF10.CSEP07,   KLF10.GSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361538,228,556 - 38,229,737 (-)MPROMDB
RGD ID:6847206
Promoter ID:MM_ACW:17866
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   ES_Cell
Transcripts:KLF10.ESEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361538,229,266 - 38,229,766 (-)MPROMDB
RGD ID:6826130
Promoter ID:MM_KWN:18310
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000044973,   NM_013692
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361538,230,381 - 38,231,047 (-)MPROMDB
RGD ID:8683628
Promoter ID:EPDNEW_M19845
Type:initiation region
Name:Klf10_1
Description:Mus musculus Kruppel-like factor 10 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381538,300,706 - 38,300,766EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1101353 AgrOrtholog
Ensembl Genes ENSMUSG00000037465 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000074043 ENTREZGENE
  ENSMUST00000074043.7 UniProtKB/Swiss-Prot
  ENSMUST00000226363.2 UniProtKB/TrEMBL
  ENSMUST00000227920 ENTREZGENE
  ENSMUST00000227920.2 UniProtKB/TrEMBL
  ENSMUST00000228416.2 UniProtKB/TrEMBL
  ENSMUST00000228732.2 UniProtKB/TrEMBL
  ENSMUST00000228772.2 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21847 UniProtKB/Swiss-Prot
MGD MGI:1101353 ENTREZGENE
NCBI Gene 21847 ENTREZGENE
PANTHER KRUEPPEL-LIKE FACTOR 10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRUEPPEL-LIKE TRANSCRIPTION FACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Klf10 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2I3BPZ3_MOUSE UniProtKB/TrEMBL
  A0A2I3BQ59_MOUSE UniProtKB/TrEMBL
  A0A2I3BRQ2_MOUSE UniProtKB/TrEMBL
  A0A2I3BRS7_MOUSE UniProtKB/TrEMBL
  KLF10_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3U3K0 ENTREZGENE, UniProtKB/TrEMBL
  Q61596_MOUSE UniProtKB/TrEMBL
  Q8C900 ENTREZGENE, UniProtKB/TrEMBL
  Q9QX13 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q64002 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-02 Klf10  Kruppel-like transcription factor 10  Klf10  Kruppel-like factor 10  Symbol and/or name change 5135510 APPROVED