Hacl1 (2-hydroxyacyl-CoA lyase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Hacl1 (2-hydroxyacyl-CoA lyase 1) Mus musculus
Analyze
Symbol: Hacl1
Name: 2-hydroxyacyl-CoA lyase 1
RGD ID: 1553280
MGI Page MGI
Description: Enables carbon-carbon lyase activity. Involved in fatty acid alpha-oxidation. Acts upstream of or within lipid metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in peroxisome. Is expressed in several structures, including adipose tissue; alimentary system; eye; genitourinary system; and nervous system. Orthologous to human HACL1 (2-hydroxyacyl-CoA lyase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1600020H07Rik; 2-HPCL; 2-hydroxyphytanoyl-CoA lyase; Hp; Hpcl; Phyh; Phyh2; phytanoyl-CoA 2-hydroxylase 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391431,329,183 - 31,364,201 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1431,320,687 - 31,363,243 (-)EnsemblGRCm39 Ensembl
GRCm381431,607,226 - 31,640,965 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1431,598,730 - 31,641,286 (-)EnsemblGRCm38mm10GRCm38
MGSCv371432,420,412 - 32,454,151 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361430,436,235 - 30,469,970 (-)NCBIMGSCv36mm8
Celera1427,864,878 - 27,898,614 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrabromodibenzodioxine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
acetamide  (ISO)
aconitine  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
Aroclor 1254  (ISO)
arsenous acid  (ISO)
atazanavir sulfate  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bromuconazole  (ISO)
buspirone  (ISO)
C60 fullerene  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
carmustine  (ISO)
chenodeoxycholic acid  (ISO)
cholesterol  (EXP)
chromium trinitrate  (EXP)
chromium(6+)  (EXP)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
deoxycholic acid  (ISO)
diarsenic trioxide  (ISO)
dibenzofurans  (EXP)
dicrotophos  (ISO)
dioxygen  (EXP)
diquat  (EXP)
doxorubicin  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
flutamide  (ISO)
folic acid  (EXP)
furan  (ISO)
glafenine  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
ivermectin  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
Muraglitazar  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel atom  (ISO)
nimesulide  (ISO)
oxycodone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
Tesaglitazar  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
tioguanine  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (EXP,ISO)
trovafloxacin  (EXP,ISO)
tungsten  (EXP)
valproic acid  (EXP,ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11171065   PMID:12477932   PMID:12520002   PMID:15489334   PMID:15644336   PMID:16141072   PMID:16141073   PMID:16602821   PMID:17208939  
PMID:21267068   PMID:21677750   PMID:21873635   PMID:24194600   PMID:24323699   PMID:27626380   PMID:28629946   PMID:29027957   PMID:30973865   PMID:32325033   PMID:35055171   PMID:38355793  


Genomics

Comparative Map Data
Hacl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391431,329,183 - 31,364,201 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1431,320,687 - 31,363,243 (-)EnsemblGRCm39 Ensembl
GRCm381431,607,226 - 31,640,965 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1431,598,730 - 31,641,286 (-)EnsemblGRCm38mm10GRCm38
MGSCv371432,420,412 - 32,454,151 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361430,436,235 - 30,469,970 (-)NCBIMGSCv36mm8
Celera1427,864,878 - 27,898,614 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.23NCBI
HACL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38315,560,699 - 15,601,569 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl315,560,699 - 15,601,852 (-)EnsemblGRCh38hg38GRCh38
GRCh37315,602,206 - 15,643,076 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36315,577,243 - 15,618,134 (-)NCBINCBI36Build 36hg18NCBI36
Celera315,540,467 - 15,581,279 (-)NCBICelera
Cytogenetic Map3p25.1NCBI
HuRef315,537,616 - 15,578,260 (-)NCBIHuRef
CHM1_1315,553,051 - 15,593,804 (-)NCBICHM1_1
T2T-CHM13v2.0315,563,097 - 15,603,888 (-)NCBIT2T-CHM13v2.0
Hacl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8166,831,293 - 6,869,410 (-)NCBIGRCr8
mRatBN7.2166,826,881 - 6,863,027 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,824,906 - 6,863,027 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx166,830,764 - 6,867,047 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0167,975,662 - 8,011,946 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0166,838,214 - 6,874,501 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0167,720,047 - 7,758,119 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl167,714,465 - 7,758,189 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0167,646,580 - 7,682,704 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,073,038 - 7,108,830 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1167,073,036 - 7,108,828 (-)NCBI
Celera168,335,334 - 8,371,457 (+)NCBICelera
Cytogenetic Map16p16NCBI
Hacl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554302,053,640 - 2,096,432 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554302,055,774 - 2,096,260 (-)NCBIChiLan1.0ChiLan1.0
HACL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2215,546,138 - 15,586,459 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1315,550,904 - 15,591,223 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0315,486,897 - 15,526,552 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1315,823,979 - 15,863,982 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl315,823,979 - 15,863,982 (-)Ensemblpanpan1.1panPan2
LOC608697
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12327,069,676 - 27,188,247 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2327,043,917 - 27,162,593 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02327,572,135 - 27,700,471 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12327,271,635 - 27,389,865 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02327,333,444 - 27,451,635 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02327,581,893 - 27,700,406 (+)NCBIUU_Cfam_GSD_1.0
Hacl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118169,684,583 - 169,717,508 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364732,823,123 - 2,856,077 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364732,823,183 - 2,856,077 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HACL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl132,766,514 - 2,840,902 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1132,786,007 - 2,840,882 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2132,714,442 - 2,737,983 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HACL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11560,360,380 - 60,433,528 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1560,322,722 - 60,433,647 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604133,390,238 - 33,465,437 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hacl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248225,079,634 - 5,145,503 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248225,078,925 - 5,189,253 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hacl1
1078 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2507
Count of miRNA genes:760
Interacting mature miRNAs:957
Transcripts:ENSMUST00000022437, ENSMUST00000127204, ENSMUST00000128629, ENSMUST00000134626, ENSMUST00000135751, ENSMUST00000139501, ENSMUST00000140078, ENSMUST00000155210, ENSMUST00000156189, ENSMUST00000156431, ENSMUST00000165955, ENSMUST00000167066, ENSMUST00000167175, ENSMUST00000171414
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
27226748Femd8_mfemur midshaft diameter 8, 10 week (mouse)141376927346737457Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
27226744Metcl6_mmetatarsal-calcaneal length 6, 5 week (mouse)143032195752937457Mouse
27226775Tibl7_mtibia length 7, 5 week (mouse)143032195748837457Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492624858179769Mouse
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141882760452827726Mouse
4141550Dbm3_mdiabetes modifier 3 (mouse)Not determined514347339143596Mouse
1300544Hypn_mhyperinsulinemia (mouse)Not determined141516061649160765Mouse
1301991Wta3_mweight adult 3 (mouse)Not determined14388747337887650Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143033525064335381Mouse
4141864Mrdq4_mmodifier of retinal degeneration QTL 4 (mouse)Not determined992324548765082Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142999699463997133Mouse
1300779Dyscalc4_mdystrophic cardiac calcinosis 4 (mouse)Not determined141221287146213007Mouse
14746973Manh76_mmandible shape 76 (mouse)142228721756287217Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143033525064335381Mouse
27226752Femd4_mfemur midshaft diameter 4, 5 week (mouse)141376927347237457Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142792195761137449Mouse


Sequence


Ensembl Acc Id: ENSMUST00000022437   ⟹   ENSMUSP00000022437
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,329,156 - 31,362,921 (-)Ensembl
GRCm38.p6 Ensembl1431,607,199 - 31,640,964 (-)Ensembl
Ensembl Acc Id: ENSMUST00000127204   ⟹   ENSMUSP00000120452
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,329,968 - 31,362,869 (-)Ensembl
GRCm38.p6 Ensembl1431,608,011 - 31,640,912 (-)Ensembl
Ensembl Acc Id: ENSMUST00000128629
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,351,724 - 31,363,214 (-)Ensembl
GRCm38.p6 Ensembl1431,629,767 - 31,641,257 (-)Ensembl
Ensembl Acc Id: ENSMUST00000134626   ⟹   ENSMUSP00000114879
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,348,383 - 31,363,129 (-)Ensembl
GRCm38.p6 Ensembl1431,626,426 - 31,641,172 (-)Ensembl
Ensembl Acc Id: ENSMUST00000135751
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,357,605 - 31,363,243 (-)Ensembl
GRCm38.p6 Ensembl1431,635,648 - 31,641,286 (-)Ensembl
Ensembl Acc Id: ENSMUST00000139501
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,329,926 - 31,332,291 (-)Ensembl
GRCm38.p6 Ensembl1431,607,969 - 31,610,334 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140078   ⟹   ENSMUSP00000154592
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,329,622 - 31,336,268 (-)Ensembl
GRCm38.p6 Ensembl1431,607,665 - 31,614,311 (-)Ensembl
Ensembl Acc Id: ENSMUST00000155210
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,352,536 - 31,362,903 (-)Ensembl
GRCm38.p6 Ensembl1431,630,579 - 31,640,946 (-)Ensembl
Ensembl Acc Id: ENSMUST00000156189
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,357,466 - 31,362,868 (-)Ensembl
GRCm38.p6 Ensembl1431,635,509 - 31,640,911 (-)Ensembl
Ensembl Acc Id: ENSMUST00000156431   ⟹   ENSMUSP00000114922
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,320,687 - 31,362,901 (-)Ensembl
GRCm38.p6 Ensembl1431,598,730 - 31,640,944 (-)Ensembl
Ensembl Acc Id: ENSMUST00000165955   ⟹   ENSMUSP00000129090
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,329,968 - 31,362,835 (-)Ensembl
GRCm38.p6 Ensembl1431,608,011 - 31,640,878 (-)Ensembl
Ensembl Acc Id: ENSMUST00000167066   ⟹   ENSMUSP00000132913
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,329,968 - 31,362,835 (-)Ensembl
GRCm38.p6 Ensembl1431,608,011 - 31,640,878 (-)Ensembl
Ensembl Acc Id: ENSMUST00000171414   ⟹   ENSMUSP00000130268
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1431,329,968 - 31,362,835 (-)Ensembl
GRCm38.p6 Ensembl1431,608,011 - 31,640,878 (-)Ensembl
RefSeq Acc Id: NM_019975   ⟹   NP_064359
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391431,329,183 - 31,362,922 (-)NCBI
GRCm381431,607,226 - 31,640,965 (-)NCBI
MGSCv371432,420,412 - 32,454,151 (-)RGD
Celera1427,864,878 - 27,898,614 (-)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036158767   ⟹   XP_036014660
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391431,329,822 - 31,364,201 (-)NCBI
Sequence:
RefSeq Acc Id: NP_064359   ⟸   NM_019975
- UniProtKB: Q543K1 (UniProtKB/Swiss-Prot),   Q9DAV1 (UniProtKB/Swiss-Prot),   Q9QXE0 (UniProtKB/Swiss-Prot),   D3YZ54 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000120452   ⟸   ENSMUST00000127204
Ensembl Acc Id: ENSMUSP00000130268   ⟸   ENSMUST00000171414
Ensembl Acc Id: ENSMUSP00000129090   ⟸   ENSMUST00000165955
Ensembl Acc Id: ENSMUSP00000022437   ⟸   ENSMUST00000022437
Ensembl Acc Id: ENSMUSP00000154592   ⟸   ENSMUST00000140078
Ensembl Acc Id: ENSMUSP00000114879   ⟸   ENSMUST00000134626
Ensembl Acc Id: ENSMUSP00000132913   ⟸   ENSMUST00000167066
Ensembl Acc Id: ENSMUSP00000114922   ⟸   ENSMUST00000156431
RefSeq Acc Id: XP_036014660   ⟸   XM_036158767
- Peptide Label: isoform X1
- UniProtKB: D3YZ54 (UniProtKB/TrEMBL)
Protein Domains
Thiamine pyrophosphate enzyme central   Thiamine pyrophosphate enzyme N-terminal TPP-   Thiamine pyrophosphate enzyme TPP-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QXE0-F1-model_v2 AlphaFold Q9QXE0 1-581 view protein structure

Promoters
RGD ID:8681840
Promoter ID:EPDNEW_M18951
Type:multiple initiation site
Name:Hacl1_1
Description:Mus musculus 2-hydroxyacyl-CoA lyase 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381431,640,961 - 31,641,021EPDNEW
RGD ID:6825054
Promoter ID:MM_KWN:16116
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000060715
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361432,423,466 - 32,424,217 (-)MPROMDB
RGD ID:6825053
Promoter ID:MM_KWN:16117
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000060361
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361432,427,616 - 32,428,367 (-)MPROMDB
RGD ID:6825055
Promoter ID:MM_KWN:16118
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Liver,   MEF_B6,   Spleen
Transcripts:NM_019975,   OTTMUST00000060362,   OTTMUST00000060363,   OTTMUST00000060374,   OTTMUST00000060375,   OTTMUST00000060376,   OTTMUST00000060377,   UC007SXW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361432,454,071 - 32,455,417 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1929657 AgrOrtholog
Ensembl Genes ENSMUSG00000021884 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000022437 ENTREZGENE
  ENSMUST00000022437.16 UniProtKB/Swiss-Prot
  ENSMUST00000127204.9 UniProtKB/TrEMBL
  ENSMUST00000134626.8 UniProtKB/TrEMBL
  ENSMUST00000140078.9 UniProtKB/TrEMBL
  ENSMUST00000156431.8 UniProtKB/Swiss-Prot
  ENSMUST00000165955.8 UniProtKB/TrEMBL
  ENSMUST00000167066.8 UniProtKB/TrEMBL
  ENSMUST00000171414.8 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.970 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPP-binding domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DHS-like_NAD/FAD-binding_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HACL1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THDP-binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thiamin_PyroP_enz_cen_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thiamin_PyroP_enz_TPP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPP_enzyme-bd_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:56794 UniProtKB/Swiss-Prot
MGD MGI:1929657 ENTREZGENE
NCBI Gene 56794 ENTREZGENE
PANTHER 2-HYDROXYACYL-COA LYASE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR43710 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TPP_enzyme_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPP_enzyme_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPP_enzyme_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hacl1 PhenoGen
Superfamily-SCOP SSF52467 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52518 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2I3BRS0_MOUSE UniProtKB/TrEMBL
  D3YZ54 ENTREZGENE, UniProtKB/TrEMBL
  D6RDE9_MOUSE UniProtKB/TrEMBL
  E9PWM4_MOUSE UniProtKB/TrEMBL
  E9Q0K0_MOUSE UniProtKB/TrEMBL
  E9Q7H7_MOUSE UniProtKB/TrEMBL
  HACL1_MOUSE UniProtKB/Swiss-Prot
  Q543K1 ENTREZGENE
  Q9DAV1 ENTREZGENE
  Q9QXE0 ENTREZGENE
UniProt Secondary Q543K1 UniProtKB/Swiss-Prot
  Q9DAV1 UniProtKB/Swiss-Prot