HACL1 (2-hydroxyacyl-CoA lyase 1)

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Gene: HACL1 (2-hydroxyacyl-CoA lyase 1) Pan paniscus

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Symbol:

HACL1

Name:

2-hydroxyacyl-CoA lyase 1

RGD ID:

11903340

Description:

ENCODES a protein that exhibits 2-hydroxyacyl-CoA lyase activity (inferred); ATP binding (inferred); carbon-carbon lyase activity (inferred); INVOLVED IN lipid metabolic process (ortholog); PARTICIPATES IN phytanic acid degradation pathway; Refsum disease pathway; ASSOCIATED WITH 3p deletion syndrome (ortholog); biotinidase deficiency (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN intracellular membrane-bounded organelle (inferred); nucleoplasm (inferred); peroxisome (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	15,546,138 - 15,586,459 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	15,550,904 - 15,591,223 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	15,486,897 - 15,526,552 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	15,823,979 - 15,863,982 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	15,823,979 - 15,863,982 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3p deletion syndrome (ISO)

biotinidase deficiency (ISO)

Chemical and Drug Induced Liver Injury (ISO)

cholestasis (ISO)

congenital myasthenic syndrome 5 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

fatty acid alpha-oxidation (IEA)

fatty acid metabolic process (IEA)

lipid metabolic process (IEA,ISO)

methyl-branched fatty acid metabolic process (IEA)

phytanic acid metabolic process (IEA)

protein targeting to peroxisome (IEA)

Cellular Component

intracellular membrane-bounded organelle (IEA)

nucleoplasm (IEA)

peroxisome (IEA)

Molecular Function

2-hydroxyacyl-CoA lyase activity (IEA)

ATP binding (IEA)

carbon-carbon lyase activity (IEA)

catalytic activity (IEA)

identical protein binding (IEA)

lyase activity (IEA)

magnesium ion binding (IEA)

protein binding (ISO)

thiamine pyrophosphate binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

phytanic acid degradation pathway (ISO)

Refsum disease pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

HACL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	15,546,138 - 15,586,459 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	15,550,904 - 15,591,223 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	15,486,897 - 15,526,552 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	15,823,979 - 15,863,982 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	15,823,979 - 15,863,982 (-)	Ensembl	panpan1.1		panPan2

HACL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	15,560,699 - 15,601,569 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	15,560,699 - 15,601,852 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	15,602,206 - 15,643,076 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	15,577,243 - 15,618,134 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	15,540,467 - 15,581,279 (-)	NCBI		Celera
Cytogenetic Map	3	p25.1	NCBI
HuRef	3	15,537,616 - 15,578,260 (-)	NCBI		HuRef
CHM1_1	3	15,553,051 - 15,593,804 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	15,563,097 - 15,603,888 (-)	NCBI		T2T-CHM13v2.0

Hacl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	31,329,183 - 31,364,201 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	31,320,687 - 31,363,243 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	31,607,226 - 31,640,965 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	31,598,730 - 31,641,286 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	32,420,412 - 32,454,151 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	30,436,235 - 30,469,970 (-)	NCBI		MGSCv36	mm8
Celera	14	27,864,878 - 27,898,614 (-)	NCBI		Celera
Cytogenetic Map	14	B	NCBI
cM Map	14	19.23	NCBI

Hacl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	6,831,293 - 6,869,410 (-)	NCBI		GRCr8
mRatBN7.2	16	6,826,881 - 6,863,027 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	6,824,906 - 6,863,027 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	6,830,764 - 6,867,047 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	7,975,662 - 8,011,946 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	6,838,214 - 6,874,501 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	7,720,047 - 7,758,119 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	7,714,465 - 7,758,189 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	7,646,580 - 7,682,704 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	7,073,038 - 7,108,830 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	7,073,036 - 7,108,828 (-)	NCBI
Celera	16	8,335,334 - 8,371,457 (+)	NCBI		Celera
Cytogenetic Map	16	p16	NCBI

Hacl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955430	2,053,640 - 2,096,432 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955430	2,055,774 - 2,096,260 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC608697
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	27,069,676 - 27,188,247 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	27,043,917 - 27,162,593 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	27,572,135 - 27,700,471 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	23	27,271,635 - 27,389,865 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	27,333,444 - 27,451,635 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	27,581,893 - 27,700,406 (+)	NCBI		UU_Cfam_GSD_1.0

Hacl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	169,684,583 - 169,717,508 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	2,823,123 - 2,856,077 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936473	2,823,183 - 2,856,077 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HACL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	2,766,514 - 2,840,902 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	2,786,007 - 2,840,882 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	2,714,442 - 2,737,983 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HACL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	60,360,380 - 60,433,528 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	60,322,722 - 60,433,647 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	33,390,238 - 33,465,437 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hacl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624822	5,079,634 - 5,145,503 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624822	5,078,925 - 5,189,253 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003826201	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034955896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034955897	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034955898	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000063216 ⟹ ENSPPAP00000040301

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	3	15,823,979 - 15,863,982 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000063223 ⟹ ENSPPAP00000040307

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	3	15,824,100 - 15,863,595 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000063225 ⟹ ENSPPAP00000040309

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	3	15,824,100 - 15,863,595 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000063227 ⟹ ENSPPAP00000040311

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	3	15,824,100 - 15,863,595 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000063228 ⟹ ENSPPAP00000040312

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	3	15,824,100 - 15,863,595 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000063230 ⟹ ENSPPAP00000040314

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	3	15,849,683 - 15,863,595 (-)	Ensembl

RefSeq Acc Id:

XM_003826201 ⟹ XP_003826249

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	2	15,546,138 - 15,586,459 (-)	NCBI
NHGRI_mPanPan1	3	15,550,904 - 15,591,223 (-)	NCBI
Mhudiblu_PPA_v0	3	15,486,897 - 15,526,552 (-)	NCBI
PanPan1.1	3	15,823,979 - 15,863,982 (-)	NCBI

Sequence:

show sequence

TCTCCCTTTACAGCCCCGAAAACGCTCCAGCTGGCCGACTCGGAGACAATGGCGAGAGGCCTCA
GAGTTCGGCTTCTTACCTGCTTTGCATAGGCAGCAATCTCCTGCTAGTCCCGCCTCCCTCTGGC
ATTCTGGCGCGCGAATGGAGGAGCCGAGAAGAGAGCGCAGTTCTGATTGGAGAACGCGCGTGTT
TACATTCTCACCTCTCCCGGGAAGTGGACGAATTTAGACCGCCTCTTCCTTCCCGTTGTTTAAG
GCAGTTGGTTGCCCTCCTGTCCGTCAGAGGTGCAGTCCCAGAGGTGGCGTGCCGCCGACTTCGC
GTTTGCCTTGCTGGGTGATTCCGCTTGTTTGCCGCCTGCGTGAGTGCTTAGAGCTTTTCGGTGG
AAGATGCCGGACAGTAACTTCGCAGAGCGCAGCGAGGAGCAGGTGTCTGGTGCTAAAGTCATCG
CTCAGGCCCTGAAAACGCAAGATGTGGAGTACATATTTGGCATCGTAGGCATCCCAGTGACCGA
AATCGCCATTGCTGCCCAGCAGCTAGGCATCAAGTACATCGGGATGAGGAATGAGCAGGCGGCT
TGTTATGCTGCCTCCGCGATTGGATATCTGACAAGCAGGCCAGGAGTCTGCCTTGTTGTTTCTG
GCCCAGGTCTCATCCATGCCTTGGGCGGTATGGCAAATGCAAACATGAACTGCTGGCCCTTGCT
TGTGATTGGTGGTTCCTCTGAAAGAAACCAAGAAACAATGGGAGCTTTCCAGGAGTTTCCTCAG
GTTGAAGCTTGTAGATTATATACCAAGTTCTCTGCCCGCCCAAGCAGCATAGAAGCTATTCCTT
TTGTTATTGAAAAGGCAGTGAGAAGCAGTATCTATGGTCGTCCAGGTGCTTGCTATGTTGACAT
ACCAGCAGATTTTGTGAACCTTCAGGTGAATGTGAATTCTATAAAGTACATGGAACGCTGCATG
TCACCTCCTATTAGCATGGCAGAAACCTCTGCTGTGTGCACGGCGGCTTCTGTTATTAGGAATG
CCAAACAACCCCTTCTTATCATCGGGAAAGGTGCTGCTTACGCTCATGCAGAAGAGAGTATCAA
GAAATTGGTGGAGCAATATAAACTGCCATTTTTGCCCACCCCTATGGGGAAGGGTGTTGTCCCT
GACAACCATCCATACTGTGTAGGTGCAGCCAGATCCAGGGCTTTGCAATTTGCTGATGTAATTG
TGTTATTTGGTGCCAGACTAAATTGGATTTTACATTTTGGACTGCCTCCAAGATATCAGCCAGA
TGTGAAGTTTATCCAGGTTGATATCTGTGCAGAAGAATTGGGGAATAATGTAAAGCCCGCTGTT
ACTTTGCTAGGAAACATACATGCTGTCACTAAGCAGCTTTTAGAGGAACTTGATAAAACACCAT
GGCAGTATCCTCCAGAGAGCAAGTGGTGGAAAACTCTGAGAGAAAAAATGAAGAGCAATGAAGC
TGCATCCAAGGAACTAGCTTCTAAAAAATCCCTGCCTATGAATTATTACACAGTATTCTACCAT
GTTCAAGAACAACTACCTAGAGACTGTTTCGTGGTAAGTGAAGGAGCAAATACTATGGACATTG
GACGGACTGTGCTTCAGAACTACCTTCCTCGTCACAGGCTTGATGCTGGTACTTTCGGAACAAT
GGGAGTTGGTTTAGGATTTGCTATTGCAGCTGCCGTGGTGGCTAAAGATAGAAGCCCTGGGCAA
TGGATCATCTGTGTGGAAGGAGACAGTGCATTTGGGTTTTCTGGCATGGAGGTAGAAACCATCT
GCAGGTACAACTTGCCAATCATACTCTTGGTAGTGAATAACAATGGAATTTACCAAGGTTTTGA
TACAGATACTTGGAAAGAAATGTTAAAATTTCAAGATGCTACTGCAGTGGTCCCTCCAATGTGT
TTGCTGCCAAATTCACATTATGAGCAAGTCATGACTGCATTTGGAGGCAAAGGGTATTTTGTAC
AAACACCAGAAGAACTCCAAAAATCCCTGAGGCAGAGCCTAGCAGACACAACTAAACCTTCTCT
TATCAACATCATGATTGAGCCACAAGCCACACGGAAGGCCCAGGATTTTCATTGGCTGACCCGC
TCTAATATGTAAATAAAGACGCCAGTTGGTGGTCTTGAGTTTTCTCTTTCTTGCAAGATGAAAT
TTTATTTTCCACAGCAAAATTACTCTACTGTTAAAATTGTGCAAAATAAAATAAACATTTAAAA
TGACA

hide sequence

RefSeq Acc Id:

XM_034955896 ⟹ XP_034811787

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	2	15,546,138 - 15,586,411 (-)	NCBI
NHGRI_mPanPan1	3	15,550,904 - 15,591,175 (-)	NCBI
Mhudiblu_PPA_v0	3	15,486,897 - 15,526,506 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003826249	(Get FASTA)	NCBI Sequence Viewer
	XP_034811787	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000040301
	ENSPPAP00000040301.1
	ENSPPAP00000040307.1
	ENSPPAP00000040309.1
	ENSPPAP00000040311.1
	ENSPPAP00000040312.1
	ENSPPAP00000040314.1

RefSeq Acc Id:	XP_003826249 ⟸ XM_003826201
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9CEC8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPDSNFAERSEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAAC YAASAIGYLTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQV EACRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVNLQVNVNSIKYMERCMS PPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVVPD NHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAVT LLGNIHAVTKQLLEELDKTPWQYPPESKWWKTLREKMKSNEAASKELASKKSLPMNYYTVFYHV QEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSPGQW IICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQGFDTDTWKEMLKFQDATAVVPPMCL LPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLADTTKPSLINIMIEPQATRKAQDFHWLTRS NM hide sequence

RefSeq Acc Id:	XP_034811787 ⟸ XM_034955896
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSPPAP00000040312 ⟸ ENSPPAT00000063228

Ensembl Acc Id:

ENSPPAP00000040311 ⟸ ENSPPAT00000063227

Ensembl Acc Id:

ENSPPAP00000040309 ⟸ ENSPPAT00000063225

Ensembl Acc Id:

ENSPPAP00000040307 ⟸ ENSPPAT00000063223

Ensembl Acc Id:

ENSPPAP00000040301 ⟸ ENSPPAT00000063216

Ensembl Acc Id:

ENSPPAP00000040314 ⟸ ENSPPAT00000063230

Protein Domains

Thiamine pyrophosphate enzyme central Thiamine pyrophosphate enzyme N-terminal TPP- Thiamine pyrophosphate enzyme TPP-binding

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000042783	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000063216.1	UniProtKB/TrEMBL
	ENSPPAT00000063223.1	UniProtKB/TrEMBL
	ENSPPAT00000063225.1	UniProtKB/TrEMBL
	ENSPPAT00000063227.1	UniProtKB/TrEMBL
	ENSPPAT00000063228.1	UniProtKB/TrEMBL
	ENSPPAT00000063230.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.970	UniProtKB/TrEMBL
	TPP-binding domain	UniProtKB/TrEMBL
InterPro	DHS-like_NAD/FAD-binding_dom	UniProtKB/TrEMBL
	HACL1-like	UniProtKB/TrEMBL
	THDP-binding	UniProtKB/TrEMBL
	Thiamin_PyroP_enz_cen_dom	UniProtKB/TrEMBL
	Thiamin_PyroP_enz_TPP-bd_dom	UniProtKB/TrEMBL
	TPP_enzyme-bd_C	UniProtKB/TrEMBL
KEGG Report	pps:100982158	UniProtKB/TrEMBL
NCBI Gene	HACL1	ENTREZGENE
PANTHER	2-HYDROXYACYL-COA LYASE 1	UniProtKB/TrEMBL
	PTHR43710	UniProtKB/TrEMBL
Pfam	TPP_enzyme_C	UniProtKB/TrEMBL
	TPP_enzyme_M	UniProtKB/TrEMBL
	TPP_enzyme_N	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52467	UniProtKB/TrEMBL
	SSF52518	UniProtKB/TrEMBL
UniProt	A0A2R9CEC8	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9CED8_PANPA	UniProtKB/TrEMBL
	A0A2R9CEJ4_PANPA	UniProtKB/TrEMBL
	A0A2R9CEK0_PANPA	UniProtKB/TrEMBL
	A0A2R9CPF1_PANPA	UniProtKB/TrEMBL
	A0A2R9CPF2_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIA

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

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Imported Annotations - SMPDB