Il11ra1 (interleukin 11 receptor subunit alpha 1) - Rat Genome Database

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Gene: Il11ra1 (interleukin 11 receptor subunit alpha 1) Mus musculus
Analyze
Symbol: Il11ra1
Name: interleukin 11 receptor subunit alpha 1
RGD ID: 1553290
MGI Page MGI
Description: Enables interleukin-11 binding activity and interleukin-11 receptor activity. Acts upstream of or within several processes, including cytokine-mediated signaling pathway; decidualization; and natural killer cell differentiation. Predicted to be located in extracellular region and membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; immune system; and nervous system. Orthologous to human IL11RA (interleukin 11 receptor subunit alpha).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI314697; enhancer trap locus homolog 2; etl-2; GP130; Il; Il-; IL-11 receptor subunit alpha-1; IL-11R subunit alpha-1; IL-11R-alpha-1; Il-11ra; Il-11ra-alpha; IL-11RA1; Il11ra; Il11ra2; interleukin 11 receptor, alpha chain 1; interleukin 11 receptor, alpha chain 2; interleukin-11 receptor subunit alpha-1; locus 2; N; novel cytokine receptor 1; NR-1; NR1
RGD Orthologs
Human
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39441,760,443 - 41,769,473 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl441,699,989 - 41,769,474 (+)EnsemblGRCm39 Ensembl
GRCm38441,760,443 - 41,769,473 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl441,699,989 - 41,769,474 (+)EnsemblGRCm38mm10GRCm38
MGSCv37441,707,316 - 41,716,346 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36441,950,869 - 41,957,984 (+)NCBIMGSCv36mm8
Celera441,421,225 - 41,430,277 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map421.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,1-dichloroethene  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
capsaicin  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlordecone  (EXP)
chlorpyrifos  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
dibutyl phthalate  (ISO)
diuron  (ISO)
ethanol  (EXP)
ferulic acid  (EXP)
finasteride  (ISO)
graphite  (ISO)
imiquimod  (EXP)
indometacin  (ISO)
methidathion  (EXP)
methimazole  (ISO)
methylmercury chloride  (ISO)
nickel atom  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (EXP)
Tributyltin oxide  (EXP)
trimellitic anhydride  (EXP)
triptonide  (EXP)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cloning of rat interleukin 11 and interleukin 11 receptor alpha chain and analysis of their expression in rat uterus in the peri-implantation period. Li R, etal., Reproduction 2001 Oct;122(4):593-600.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice. Tebbutt NC, etal., Nat Med 2002 Oct;8(10):1089-97.
Additional References at PubMed
PMID:7813775   PMID:7957045   PMID:8637716   PMID:8662802   PMID:8808281   PMID:8973540   PMID:9073505   PMID:9090788   PMID:9310465   PMID:9373251   PMID:9500603   PMID:9679067  
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11123313   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12746919   PMID:12819125   PMID:12831858   PMID:14764690   PMID:15489334  
PMID:15499555   PMID:15537430   PMID:15538938   PMID:15699166   PMID:15782199   PMID:15883645   PMID:15940362   PMID:16141072   PMID:16141073   PMID:16143138   PMID:17881769   PMID:18431520  
PMID:18617680   PMID:18805458   PMID:19097069   PMID:19121317   PMID:19144959   PMID:19185844   PMID:19734214   PMID:21267068   PMID:21297079   PMID:21677750   PMID:21709156   PMID:21741611  
PMID:21873635   PMID:22253262   PMID:22306691   PMID:22715999   PMID:22992748   PMID:23079657   PMID:23321674   PMID:23948300   PMID:24909139   PMID:24971735   PMID:25078447   PMID:26255596  
PMID:27872193   PMID:28735867   PMID:28864002   PMID:29160304   PMID:30282020   PMID:30355616   PMID:31481496   PMID:32569771   PMID:32656894   PMID:33082445   PMID:33196831   PMID:33397952  
PMID:33863879   PMID:34108253   PMID:34239012   PMID:34321999   PMID:34530329   PMID:35364055   PMID:36283092   PMID:36470928   PMID:36685040   PMID:36924234   PMID:38468436   PMID:39128004  


Genomics

Comparative Map Data
Il11ra1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39441,760,443 - 41,769,473 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl441,699,989 - 41,769,474 (+)EnsemblGRCm39 Ensembl
GRCm38441,760,443 - 41,769,473 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl441,699,989 - 41,769,474 (+)EnsemblGRCm38mm10GRCm38
MGSCv37441,707,316 - 41,716,346 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36441,950,869 - 41,957,984 (+)NCBIMGSCv36mm8
Celera441,421,225 - 41,430,277 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map421.94NCBI
IL11RA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38934,652,185 - 34,661,902 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl934,652,162 - 34,661,902 (+)EnsemblGRCh38hg38GRCh38
GRCh37934,652,182 - 34,661,899 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36934,643,932 - 34,651,884 (+)NCBINCBI36Build 36hg18NCBI36
Build 34934,643,931 - 34,650,815NCBI
Celera934,583,653 - 34,593,355 (+)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef934,606,462 - 34,616,181 (+)NCBIHuRef
CHM1_1934,651,965 - 34,661,682 (+)NCBICHM1_1
T2T-CHM13v2.0934,670,713 - 34,680,432 (+)NCBIT2T-CHM13v2.0
Il11ra1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8561,727,650 - 61,737,265 (+)NCBIGRCr8
mRatBN7.2556,931,824 - 56,941,408 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl556,935,516 - 56,941,408 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx558,908,620 - 58,915,700 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0560,727,450 - 60,734,530 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0560,713,513 - 60,720,605 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0558,149,150 - 58,159,072 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl558,151,985 - 58,159,072 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0562,673,838 - 62,683,436 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4559,192,698 - 59,199,783 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1559,192,876 - 59,199,962 (+)NCBI
Celera555,526,482 - 55,533,561 (+)NCBICelera
Cytogenetic Map5q22NCBI
Il11ra
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554721,475,178 - 1,482,206 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554721,474,802 - 1,485,352 (-)NCBIChiLan1.0ChiLan1.0
IL11RA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11151,324,915 - 51,341,981 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1149,953,267 - 49,970,134 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01152,265,652 - 52,282,519 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1152,268,766 - 52,275,323 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11150,928,355 - 50,945,221 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01150,796,497 - 50,813,366 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01151,561,269 - 51,578,140 (+)NCBIUU_Cfam_GSD_1.0
Il11ra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947166,184,831 - 166,211,247 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365242,735,507 - 2,742,660 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365242,732,477 - 2,743,044 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL11RA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1032,139,063 - 32,146,138 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11032,138,984 - 32,149,315 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21036,278,889 - 36,289,165 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL11RA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11245,959,370 - 45,970,563 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1245,955,863 - 45,969,310 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603843,076,251 - 43,087,084 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il11ra
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473639,046,176 - 39,055,306 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473639,043,972 - 39,055,689 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Il11ra1
164 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1318
Count of miRNA genes:544
Interacting mature miRNAs:642
Transcripts:ENSMUST00000098132, ENSMUST00000108040, ENSMUST00000108041, ENSMUST00000108042, ENSMUST00000140894, ENSMUST00000142059, ENSMUST00000145445, ENSMUST00000146608, ENSMUST00000152748, ENSMUST00000155538
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301203Alcp8_malcohol preference locus 8 (mouse)Not determined41739516051395290Mouse
1301586Stheal3_msoft tissue heal 3 (mouse)Not determined42865844262658566Mouse
10401115Pgia35_mproteoglycan induced arthritis 35 (mouse)Not determined41256237746562509Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
1558992Ses8_msalmonella enteritidis susceptibility 8 (mouse)Not determined4868324042683429Mouse
4141302Ssrq5_mstress response QTL 5 (mouse)Not determined868324042683430Mouse
4141555Nbwa2_mNZB and NZW autoimmunity 2 (mouse)Not determined41789251551892635Mouse
10412178Habiir2_mhyperoxic acute lung injury imprinted region 2 (mouse)Not determined43945212663283678Mouse
1300574Im2_mimmunoregulatory 2 (mouse)Not determined42807768262077816Mouse
12880405Jcdq1_mjoint cartilage degeneration QTL 1 (mouse)41256237746562509Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763283678Mouse
1301697Sluc18_msusceptibility to lung cancer 18 (mouse)Not determined42237344856373612Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
1357877Synch1_msynechia 1 (mouse)Not determined42870992562710107Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
25440481Moaq1_mmodifier of alien QTL 1 (mouse)41950000046000000Mouse
1301237Alcp7_malcohol preference locus 7 (mouse)Not determined41739516051395290Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
1302075Bdln6_mbody length 6 (mouse)Not determined42237344856373612Mouse
1302010Wta1_mweight adult 1 (mouse)Not determined4868324042683429Mouse
4142290Ssrq9_mstress response QTL 9 (mouse)Not determined3439516046332776Mouse
1301437Scon1_msucrose consumption 1 (mouse)Not determined42237344856373612Mouse
10401905Sicd3_mseizure-induced cell death 3 (mouse)Not determined4939552543760862Mouse
1301473Triglq1_mtriglyceride QTL 1 (mouse)Not determined4868324042683429Mouse
1300769Pcyts2_mplasmacytoma susceptibility 2 (mouse)Not determined42211194456112145Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1301990Arvm1_mautoimmune renal vasculitis 1 (mouse)Not determined42933264663332776Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
1302058Hrtfm3_mheart failure modifier 3 (mouse)Not determined42211194456112145Mouse
1302184Aaom1_mautoimmune aoritis in MRL mice 1 (mouse)Not determined42432229946332776Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
1302125Lxw1_mlupus BXSB x NZW 1 (mouse)Not determined4868324042683429Mouse

Markers in Region
AI314697  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4A5UniSTS
cM Map412.7UniSTS
cM Map412.7UniSTS
Whitehead/MRC_RH4662.88UniSTS
Whitehead/MRC_RH4663.65UniSTS
Il11ra1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4A5UniSTS
cM Map412.7UniSTS
cM Map412.7UniSTS
cM Map412.7UniSTS
Il11ra1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4A5UniSTS
cM Map412.7UniSTS
Il11ra1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4A5UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001163401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001172054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK143811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL807796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY149476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY777524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U14412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U51637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X74953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X94162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X94163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000098132   ⟹   ENSMUSP00000095736
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,760,196 - 41,769,474 (+)Ensembl
GRCm38.p6 Ensembl441,760,196 - 41,769,474 (+)Ensembl
Ensembl Acc Id: ENSMUST00000108040   ⟹   ENSMUSP00000103675
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,760,454 - 41,769,474 (+)Ensembl
GRCm38.p6 Ensembl441,760,454 - 41,769,474 (+)Ensembl
Ensembl Acc Id: ENSMUST00000108041   ⟹   ENSMUSP00000103676
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,699,989 - 41,769,474 (+)Ensembl
GRCm38.p6 Ensembl441,699,989 - 41,769,474 (+)Ensembl
Ensembl Acc Id: ENSMUST00000108042   ⟹   ENSMUSP00000103677
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,762,309 - 41,769,474 (+)Ensembl
GRCm38.p6 Ensembl441,762,309 - 41,769,474 (+)Ensembl
Ensembl Acc Id: ENSMUST00000140894
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,760,512 - 41,764,009 (+)Ensembl
GRCm38.p6 Ensembl441,760,512 - 41,764,009 (+)Ensembl
Ensembl Acc Id: ENSMUST00000142059
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,768,448 - 41,769,474 (+)Ensembl
GRCm38.p6 Ensembl441,768,448 - 41,769,474 (+)Ensembl
Ensembl Acc Id: ENSMUST00000145445
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,762,395 - 41,768,060 (+)Ensembl
GRCm38.p6 Ensembl441,762,395 - 41,768,060 (+)Ensembl
Ensembl Acc Id: ENSMUST00000146608
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,760,498 - 41,766,126 (+)Ensembl
GRCm38.p6 Ensembl441,760,498 - 41,766,126 (+)Ensembl
Ensembl Acc Id: ENSMUST00000152748
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,767,934 - 41,768,468 (+)Ensembl
GRCm38.p6 Ensembl441,767,934 - 41,768,468 (+)Ensembl
Ensembl Acc Id: ENSMUST00000155538
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,767,799 - 41,769,474 (+)Ensembl
GRCm38.p6 Ensembl441,767,799 - 41,769,474 (+)Ensembl
RefSeq Acc Id: NM_001163401   ⟹   NP_001156873
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,760,443 - 41,769,473 (+)NCBI
GRCm38441,760,443 - 41,769,473 (+)NCBI
MGSCv37441,707,316 - 41,716,346 (+)RGD
Celera441,421,225 - 41,430,277 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001172054   ⟹   NP_001165525
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,760,443 - 41,769,473 (+)NCBI
GRCm38441,760,443 - 41,769,473 (+)NCBI
MGSCv37441,707,316 - 41,716,346 (+)RGD
Celera441,421,225 - 41,430,277 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_010549   ⟹   NP_034679
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,762,310 - 41,769,473 (+)NCBI
GRCm38441,762,310 - 41,769,473 (+)NCBI
MGSCv37441,707,316 - 41,716,346 (+)RGD
Celera441,421,225 - 41,430,277 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_034679   ⟸   NM_010549
- Peptide Label: precursor
- UniProtKB: A2AMS4 (UniProtKB/Swiss-Prot),   Q6NSQ0 (UniProtKB/Swiss-Prot),   Q64385 (UniProtKB/Swiss-Prot),   Q3UIV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001156873   ⟸   NM_001163401
- Peptide Label: precursor
- UniProtKB: A2AMS4 (UniProtKB/Swiss-Prot),   Q6NSQ0 (UniProtKB/Swiss-Prot),   Q64385 (UniProtKB/Swiss-Prot),   Q3UIV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001165525   ⟸   NM_001172054
- Peptide Label: precursor
- UniProtKB: A2AMS4 (UniProtKB/Swiss-Prot),   Q6NSQ0 (UniProtKB/Swiss-Prot),   Q64385 (UniProtKB/Swiss-Prot),   Q3UIV4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000103676   ⟸   ENSMUST00000108041
Ensembl Acc Id: ENSMUSP00000103675   ⟸   ENSMUST00000108040
Ensembl Acc Id: ENSMUSP00000103677   ⟸   ENSMUST00000108042
Ensembl Acc Id: ENSMUSP00000095736   ⟸   ENSMUST00000098132
Protein Domains
Fibronectin type-III   Ig-like   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64385-F1-model_v2 AlphaFold Q64385 1-432 view protein structure

Promoters
RGD ID:6835496
Promoter ID:MM_KWN:37186
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000108040,   OTTMUST00000015312,   OTTMUST00000015314,   OTTMUST00000015315,   UC008SJQ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36441,706,166 - 41,707,422 (+)MPROMDB
RGD ID:6835498
Promoter ID:MM_KWN:37187
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   Brain,   Lung
Transcripts:UC008SJS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36441,707,426 - 41,707,967 (+)MPROMDB
RGD ID:6835495
Promoter ID:MM_KWN:37188
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   Kidney,   MEF_B6
Transcripts:ENSMUST00000108042,   OTTMUST00000062577
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36441,708,286 - 41,708,957 (+)MPROMDB
RGD ID:6883360
Promoter ID:EPDNEW_M5018
Type:initiation region
Name:Il11ra1_1
Description:Mus musculus interleukin 11 receptor, alpha chain 1 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5019  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38441,760,469 - 41,760,529EPDNEW
RGD ID:6883136
Promoter ID:EPDNEW_M5019
Type:multiple initiation site
Name:Il11ra1_2
Description:Mus musculus interleukin 11 receptor, alpha chain 1 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5018  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38441,762,361 - 41,762,421EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107426 AgrOrtholog
Ensembl Genes ENSMUSG00000055392
  ENSMUSG00000073889 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000098132 ENTREZGENE
  ENSMUST00000098132.11 UniProtKB/Swiss-Prot
  ENSMUST00000108040 ENTREZGENE
  ENSMUST00000108040.8 UniProtKB/Swiss-Prot
  ENSMUST00000108041.8 UniProtKB/Swiss-Prot
  ENSMUST00000108042 ENTREZGENE
  ENSMUST00000108042.3 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hematopoietin_rcpt_L_F3_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Type-I_Cytokine_Rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16157 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:107426 ENTREZGENE
NCBI Gene 16157 ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INTERLEUKIN-11 RECEPTOR SUBUNIT ALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Il11ra1 PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEMATOPO_REC_L_F3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AMS4 ENTREZGENE
  I11RA_MOUSE UniProtKB/Swiss-Prot
  Q3U294_MOUSE UniProtKB/TrEMBL
  Q3UIV4 ENTREZGENE, UniProtKB/TrEMBL
  Q64385 ENTREZGENE
  Q6NSQ0 ENTREZGENE
UniProt Secondary A2AMS4 UniProtKB/Swiss-Prot
  Q6NSQ0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-03 Il11ra1  interleukin 11 receptor subunit alpha 1  Il11ra1  interleukin 11 receptor, alpha chain 1  Symbol and/or name change 5135510 APPROVED