Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Atf3 (activating transcription factor 3) Mus musculus
Symbol: Atf3
Name: activating transcription factor 3
RGD ID: 10198
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including gluconeogenesis; negative regulation of nitrogen compound metabolic process; and skeletal muscle cell differentiation. Localizes to nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and limb long bone. Orthologous to human ATF3 (activating transcription factor 3); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH (S)-nicotine; 1,1-dichloroethene; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cAMP-dependent transcription factor ATF-3; cyclic AMP-dependent transcription factor ATF-3; LRG-; LRG-21; transcription factor LRG-21
Homo sapiens (human) : ATF3 (activating transcription factor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atf3 (activating transcription factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atf3 (activating transcription factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ATF3 (activating transcription factor 3)
Canis lupus familiaris (dog) : ATF3 (activating transcription factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atf3 (activating transcription factor 3)
Sus scrofa (pig) : ATF3 (activating transcription factor 3)
Chlorocebus sabaeus (African green monkey) : ATF3 (activating transcription factor 3)
Heterocephalus glaber (naked mole-rat) : Atf3 (activating transcription factor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391190,902,493 - 190,915,530 (-)NCBI
GRCm381191,170,296 - 191,183,333 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1191,170,296 - 191,218,039 (-)EnsemblGRCm38mm10GRCm38
MGSCv371192,994,175 - 193,007,212 (-)NCBIGRCm37mm9NCBIm37
MGSCv361192,870,911 - 192,883,948 (-)NCBImm8
Celera1198,095,832 - 198,108,890 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map196.28NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Atf3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10198
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.