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Gene: Atf3 (activating transcription factor 3) Mus musculus
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Symbol: Atf3
Name: activating transcription factor 3
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several processes, including gluconeogenesis; negative regulation of nitrogen compound metabolic process; and skeletal muscle cell differentiation. Localizes to the nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and limb long bone. Orthologous to human ATF3 (activating transcription factor 3); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH (S)-nicotine; 1,1-dichloroethene; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cAMP-dependent transcription factor ATF-3; cyclic AMP-dependent transcription factor ATF-3; LRG-21; transcription factor LRG-21
Orthologs:
Homo sapiens (human) : ATF3 (activating transcription factor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atf3 (activating transcription factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atf3 (activating transcription factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ATF3 (activating transcription factor 3)
Canis lupus familiaris (dog) : ATF3 (activating transcription factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atf3 (activating transcription factor 3)
Sus scrofa (pig) : ATF3 (activating transcription factor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381191,170,296 - 191,183,333 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371192,994,175 - 193,007,212 (-)NCBIGRCm37mm9NCBIm37
MGSCv361192,870,911 - 192,883,948 (-)NCBImm8
Celera1198,095,832 - 198,108,890 (-)NCBICelera
Cytogenetic Map1 H6NCBI
cM Map196.28NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Atf3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10198
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.