Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Egr1 (early growth response 1) Mus musculus
Symbol: Egr1
Name: early growth response 1
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including cellular response to gamma radiation; circadian regulation of gene expression; and regulation of cellular biosynthetic process. Localizes to nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; genitourinary system; and jaw. Used to study myelodysplastic syndrome. Human ortholog(s) of this gene implicated in asthma. Orthologous to human EGR1 (early growth response 1); PARTICIPATES IN long term potentiation; prion disease pathway; INTERACTS WITH (-)-anisomycin; (20R)-protopanaxadiol; (S)-nicotine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A530045N19Rik; early growth response protein 1; egr; Egr-1; ETR103; Krox-1; Krox-24; Krox-24 nuclear protein; Krox24; nerve growth factor-induced protein A; NGF1-A; NGFI-A; NGFIA; TIS8; transcription factor Zif268; Zenk; Zfp-6; Zif268; zinc finger protein Krox-24
Homo sapiens (human) : EGR1 (early growth response 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Egr1 (early growth response 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Egr1 (early growth response 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EGR1 (early growth response 1)
Canis lupus familiaris (dog) : EGR1 (early growth response 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Egr1 (early growth response 1)
Sus scrofa (pig) : EGR1 (early growth response 1)
Chlorocebus sabaeus (African green monkey) : EGR1 (early growth response 1)
Heterocephalus glaber (naked mole-rat) : Egr1 (early growth response 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1834,859,823 - 34,864,984 (+)EnsemblGRCm38mm10GRCm38
GRCm381834,861,207 - 34,864,956 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371835,020,861 - 35,024,610 (+)NCBIGRCm37mm9NCBIm37
MGSCv361834,987,181 - 34,990,930 (+)NCBImm8
Celera1835,315,402 - 35,319,152 (+)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1818.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Egr1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10512
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.