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Gene: Egr1 (early growth response 1) Mus musculus
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Symbol: Egr1
Name: early growth response 1
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including cellular response to gamma radiation; circadian regulation of gene expression; and regulation of cellular biosynthetic process. Localizes to nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; genitourinary system; and jaw. Used to study myelodysplastic syndrome. Human ortholog(s) of this gene implicated in asthma. Orthologous to human EGR1 (early growth response 1); PARTICIPATES IN long term potentiation; prion disease pathway; INTERACTS WITH (-)-anisomycin; (20R)-protopanaxadiol; (S)-nicotine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A530045N19Rik; early growth response protein 1; egr; Egr-1; ETR103; Krox-1; Krox-24; Krox-24 nuclear protein; Krox24; nerve growth factor-induced protein A; NGF1-A; NGFI-A; NGFIA; TIS8; transcription factor Zif268; Zenk; Zfp-6; Zif268; zinc finger protein Krox-24
Orthologs:
Homo sapiens (human) : EGR1 (early growth response 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Egr1 (early growth response 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Egr1 (early growth response 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EGR1 (early growth response 1)
Canis lupus familiaris (dog) : EGR1 (early growth response 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Egr1 (early growth response 1)
Sus scrofa (pig) : EGR1 (early growth response 1)
Chlorocebus sabaeus (African green monkey) : EGR1 (early growth response 1)
Heterocephalus glaber (naked mole-rat) : Egr1 (early growth response 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1834,859,823 - 34,864,984 (+)EnsemblGRCm38mm10GRCm38
GRCm381834,861,207 - 34,864,956 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371835,020,861 - 35,024,610 (+)NCBIGRCm37mm9NCBIm37
MGSCv361834,987,181 - 34,990,930 (+)NCBImm8
Celera1835,315,402 - 35,319,152 (+)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1818.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Egr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10512
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.