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Gene: Ppara (peroxisome proliferator activated receptor alpha) Mus musculus
Symbol: Ppara
Name: peroxisome proliferator activated receptor alpha
Description: Exhibits several functions, including DNA-binding transcription factor activity; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and transcription factor binding activity. Involved in several processes, including circadian regulation of gene expression; enamel mineralization; and positive regulation of cellular metabolic process. Predicted to localize to the RNA polymerase II transcription factor complex and nucleoplasm. Used to study diabetes mellitus. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; lipid metabolism disorder; and myocardial infarction. Is expressed in several structures, including adipose tissue; early conceptus; heart; liver; and oocyte. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha); PARTICIPATES IN hepatitis C pathway; INTERACTS WITH (S)-naringenin; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4933429D07Rik; AI118064; AW742785; expressed sequence AI118064; Nr1c1; nuclear receptor subfamily 1 group C member 1; peroxisome proliferator-activated receptor alpha; Ppar; PPAR-alpha; PPARalpha; RIKEN cDNA 4933429D07 gene
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1585,734,983 - 85,802,819 (+)Ensembl
GRCm381585,734,910 - 85,806,851 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371585,565,994 - 85,637,281 (+)NCBIGRCm37mm9NCBIm37
MGSCv361585,563,542 - 85,630,585 (+)NCBImm8
Celera1587,868,281 - 87,938,913 (+)NCBICelera
Cytogenetic Map15 E2NCBI
cM Map1540.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences