Nfe2l2 (nuclear factor, erythroid derived 2, like 2) - Rat Genome Database

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Gene: Nfe2l2 (nuclear factor, erythroid derived 2, like 2) Mus musculus
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Symbol: Nfe2l2
Name: nuclear factor, erythroid derived 2, like 2
RGD ID: 734432
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including PERK-mediated unfolded protein response; positive regulation of cellular biosynthetic process; and regulation of reactive oxygen species metabolic process. Acts upstream of or within several processes, including cellular response to copper ion; cellular response to drug; and endoplasmic reticulum unfolded protein response. Located in chromatin; cytosol; and nucleus. Part of protein-DNA complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; cataract; hepatocellular carcinoma; macular degeneration; and tuberculosis. Orthologous to human NFE2L2 (nuclear factor, erythroid 2 like 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI194320; NF-E2-related factor 2; NFE2-related factor 2; Nr; Nrf2; nuclear factor erythroid 2-related factor 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39275,505,857 - 75,535,007 (-)NCBIGRCm39mm39
GRCm39 Ensembl275,505,857 - 75,534,985 (-)Ensembl
GRCm38275,675,513 - 75,704,663 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl275,675,513 - 75,704,641 (-)EnsemblGRCm38mm10GRCm38
MGSCv37275,513,576 - 75,542,698 (-)NCBIGRCm37mm9NCBIm37
MGSCv36275,476,358 - 75,505,480 (-)NCBImm8
Celera277,336,615 - 77,365,680 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map244.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model