Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Nfe2l2 (nuclear factor, erythroid derived 2, like 2) Mus musculus
Analyze
Symbol: Nfe2l2
Name: nuclear factor, erythroid derived 2, like 2
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription factor binding activity. Involved in several processes, including PERK-mediated unfolded protein response; positive regulation of cellular biosynthetic process; and regulation of reactive oxygen species metabolic process. Localizes to several cellular components, including chromatin; cytosol; and protein-DNA complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; cataract; hepatocellular carcinoma; and macular degeneration. Orthologous to human NFE2L2 (nuclear factor, erythroid 2 like 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI194320; NF-E2-related factor 2; NFE2-related factor 2; Nrf2; nuclear factor erythroid 2-related factor 2
Orthologs:
Homo sapiens (human) : NFE2L2 (nuclear factor, erythroid 2 like 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nfe2l2 (nuclear factor, erythroid 2-like 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfe2l2 (nuclear factor, erythroid 2 like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NFE2L2 (nuclear factor, erythroid 2 like 2)
Canis lupus familiaris (dog) : NFE2L2 (nuclear factor, erythroid 2 like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfe2l2 (nuclear factor, erythroid 2 like 2)
Sus scrofa (pig) : NFE2L2 (nuclear factor, erythroid 2 like 2)
Chlorocebus sabaeus (African green monkey) : NFE2L2 (nuclear factor, erythroid 2 like 2)
Heterocephalus glaber (naked mole-rat) : Nfe2l2 (nuclear factor, erythroid 2 like 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl275,675,513 - 75,704,641 (-)EnsemblGRCm38mm10GRCm38
GRCm38275,675,513 - 75,704,663 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37275,513,576 - 75,542,698 (-)NCBIGRCm37mm9NCBIm37
MGSCv36275,476,358 - 75,505,480 (-)NCBImm8
Celera277,336,615 - 77,365,680 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map244.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model