Gstp1 (glutathione S-transferase, pi 1) - Rat Genome Database

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Gene: Gstp1 (glutathione S-transferase, pi 1) Mus musculus
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Symbol: Gstp1
Name: glutathione S-transferase, pi 1
RGD ID: 1620115
MGI Page MGI
Description: Exhibits JUN kinase binding activity; glutathione transferase activity; and kinase regulator activity. Involved in several processes, including negative regulation of cell population proliferation; negative regulation of intracellular signal transduction; and negative regulation of macromolecule metabolic process. Localizes to protein-containing complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including brain disease (multiple); carcinoma (multiple); hematologic cancer (multiple); neurodegenerative disease (multiple); and respiratory system disease (multiple). Orthologous to human GSTP1 (glutathione S-transferase pi 1); PARTICIPATES IN glutathione conjugation pathway; paracetamol pharmacokinetics pathway; glutathione metabolic pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glutathione S-transferase P 1; Gst; GST class-pi; Gst p-1; gst P1; GST YF-YF; GST-piB; GstpiB; preadipocyte growth factor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm3266  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39194,085,411 - 4,087,912 (-)NCBIGRCm39mm39
GRCm39 Ensembl194,085,407 - 4,087,985 (-)Ensembl
GRCm38194,035,411 - 4,037,912 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl194,035,407 - 4,037,985 (-)EnsemblGRCm38mm10GRCm38
MGSCv37194,035,411 - 4,037,912 (-)NCBIGRCm37mm9NCBIm37
MGSCv36194,035,411 - 4,037,912 (-)NCBImm8
Celera193,906,327 - 3,908,828 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map193.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Coronary Syndrome  (ISO)
acute kidney failure  (ISO)
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
Airway Obstruction  (ISO)
allergic disease  (ISO)
Alzheimer's disease  (IEP,ISO)
amphetamine abuse  (ISO)
amyotrophic lateral sclerosis  (ISO)
asthma  (IAGP,ISO)
atopic dermatitis  (ISO)
autistic disorder  (ISO)
bone marrow disease  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
bronchiolo-alveolar adenocarcinoma  (ISO)
Bronchopulmonary Dysplasia  (ISO)
bronchus carcinoma  (ISO)
carcinoma  (ISO)
carotid artery disease  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chemotherapy-Induced Febrile Neutropenia  (ISO)
cholangiocarcinoma  (ISO)
Cholangiofibrosis  (ISO)
cholestasis  (ISO)
Chromosome Aberrations  (ISO)
Chronic Cerebral Hypoperfusion  (ISO)
chronic myeloid leukemia  (ISO)
chronic obstructive pulmonary disease  (ISO)
clear cell renal cell carcinoma  (ISO)
colorectal adenoma  (ISO)
Colorectal Neoplasms  (ISO)
conjunctivochalasis  (ISO)
contact dermatitis  (ISO)
Cough  (ISO)
cystic fibrosis  (ISO)
diffuse large B-cell lymphoma  (ISO)
Disease Progression  (ISO)
drug allergy  (ISO)
Drug-Induced Leukopenia  (ISO)
Drug-induced Neutropenia  (ISO)
esophagus squamous cell carcinoma  (ISO)
essential tremor  (ISO)
Experimental Liver Neoplasms  (ISO)
Experimental Seizures  (ISO)
Gallbladder Neoplasms  (ISO)
Graves' disease  (ISO)
hematopoietic system disease  (ISO)
hepatocellular carcinoma  (ISO)
high grade glioma  (ISO)
Hodgkin's lymphoma  (ISO)
hypertension  (ISO)
intellectual disability  (ISO)
Kidney Calculi  (ISO)
kidney disease  (ISO)
Kuhnt-Junius degeneration  (ISO)
Laryngeal Neoplasms  (ISO)
late onset Parkinson's disease  (ISO)
liver disease  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
lymphoid leukemia  (ISO)
malignant astrocytoma  (ISO)
melanoma  (ISO)
meningitis  (ISO)
mitochondrial metabolism disease  (ISO)
movement disease  (ISO)
multiple myeloma  (ISO)
multiple sclerosis  (ISO)
myelodysplastic syndrome  (ISO)
myeloid leukemia  (ISO)
Myocardial Ischemia  (ISO)
Necrosis  (ISO)
non-alcoholic fatty liver disease  (ISO)
oral squamous cell carcinoma  (ISO)
osteoporosis  (ISO)
osteosarcoma  (ISO)
ovarian cancer  (ISO)
pancreatic cancer  (ISO)
pancreatic ductal carcinoma  (ISO)
Parkinson's disease  (ISO)
Perennial Allergic Rhinitis  (ISO)
peripheral nervous system disease  (ISO)
peritonitis  (ISO)
Plasmodium falciparum malaria  (ISO)
pre-eclampsia  (ISO)
pre-malignant neoplasm  (ISO)
prostate cancer  (ISO)
prostate carcinoma in situ  (ISO)
prostatic hypertrophy  (ISO)
Prostatic Neoplasms  (ISO)
Pseudomonas Infections  (ISO)
psoriasis  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (IEP)
Respiratory Sounds  (ISO)
respiratory system disease  (ISO)
sarcoma  (ISO)
senile cataract  (ISO)
squamous cell carcinoma  (ISO)
Stomach Neoplasms  (ISO)
substance-induced psychosis  (ISO)
testicular cancer  (ISO)
toxic encephalopathy  (ISO)
type 2 diabetes mellitus  (ISO)
Ureteral Calculi  (ISO)
urinary bladder cancer  (ISO)
vestibular disease  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-artemisinin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(3,4-dihydroxyphenyl)acetic acid  (ISO)
(R)-lipoic acid  (ISO)
1,2-Dibromo-3-chloropropane  (ISO)
1,2-dichlorobenzene  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
1,4-phenylenediamine  (ISO)
1-\{2-[(4-chlorobenzyl)sulfanyl]-2-(2,4-dichlorophenyl)ethyl\}-1H-imidazole  (ISO)
1-bromopropane  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-Hydroxypyrene  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2,2-tetramine  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP,ISO)
2,4,6-trinitrotoluene  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,5-di-tert-butylbenzene-1,4-diol  (ISO)
2,5-hexanedione  (ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP,ISO)
2-acetamidofluorene  (ISO)
2-Acetoxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine  (ISO)
2-allylphenol  (ISO)
2-amino-4,6-dinitrotoluene  (ISO)
2-amino-7-methyl-1,7-dihydro-6H-purin-6-one  (ISO)
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one  (ISO)
2-hexenal  (ISO)
2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester  (ISO)
2-methoxyethanol  (ISO)
2-nitrofluorene  (ISO)
2-phenylpropanal  (ISO)
2-tert-butylhydroquinone  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-methylcholanthrene  (ISO)
3-nitropropanoic acid  (ISO)
3-phenoxybenzoic acid  (ISO)
3-phenylprop-2-enal  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4'-hydroxydiclofenac  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
4-Chloronitrobenzene  (ISO)
4-hydroxynon-2-enal  (EXP,ISO)
4-Propylphenol  (ISO)
4-vinylcyclohexene dioxide  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-fluorouracil  (ISO)
5-hydroxydiclofenac  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (ISO)
aclacinomycin A  (ISO)
acridine orange  (ISO)
acridine orange free base  (ISO)
acrolein  (EXP,ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
aflatoxin B1 exo-8,9-epoxide  (ISO)
aldosterone  (ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
allyl isothiocyanate  (ISO)
alpha-hexachlorocyclohexane  (ISO)
alpha-methyl-L-dopa  (ISO)
alpha-naphthoflavone  (ISO)
amitriptyline  (ISO)
ammonium chloride  (ISO)
amphotericin B  (ISO)
angelica lactone  (EXP)
anthracene-1,8,9-triol  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (ISO)
artesunate  (ISO)
asbestos  (ISO)
atovaquone  (ISO)
ATP  (ISO)
atrazine  (EXP,ISO)
Aurothioglucose  (ISO)
avobenzone  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[c]phenanthrene  (ISO)
BENZO[G]CHRYSENE  (ISO)
Benzo[k]fluoranthene  (EXP)
benzopyran  (ISO)
benzyl isothiocyanate  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
betamethasone dipropionate  (ISO)
bifenthrin  (EXP)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (ISO)
bromindione  (ISO)
Bucillamine  (ISO)
bufalin  (ISO)
buspirone  (ISO)
busulfan  (ISO)
buta-1,3-diene  (EXP)
butylated hydroxyanisole  (EXP,ISO)
butyric acid  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cafestol  (ISO)
camptothecin  (ISO)
capsaicin  (ISO)
captafol  (ISO)
captan  (EXP,ISO)
carbamazepine-10,11-epoxide  (ISO)
carbon nanotube  (EXP,ISO)
carboplatin  (ISO)
carmustine  (ISO)
carnosic acid  (ISO)
cefaloridine  (ISO)
celecoxib  (ISO)
cerium trichloride  (ISO)
chlorambucil  (ISO)
chloramphenicol palmitate  (ISO)
chlorobenzene  (ISO)
chloroethene  (ISO)
chloropicrin  (ISO)
chlorotrianisene  (ISO)
chlortetracycline  (ISO)
chromium(6+)  (EXP)
cimetidine  (ISO)
cis-caffeic acid  (ISO)
cisplatin  (ISO)
clobetasol  (EXP)
clofazimine  (ISO)
clofibrate  (EXP,ISO)
clomipramine  (ISO)
clotrimazole  (ISO)
clozapine  (ISO)
cobamamide  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (EXP,ISO)
crocidolite asbestos  (ISO)
crotonaldehyde  (ISO)
crystal violet  (ISO)
cumene  (ISO)
cumene hydroperoxide  (ISO)
curcumin  (ISO)
cyclohexanols  (ISO)
cyclophosphamide  (EXP,ISO)
cycloprothrin  (ISO)
cypermethrin  (ISO)
dapsone  (EXP)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
Diallyl sulfide  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dienestrol  (ISO)
diethyl maleate  (ISO)
diethyldithiocarbamic acid  (ISO)
diethylstilbestrol  (ISO)
dihydrolipoic acid  (ISO)
dimethylarsinic acid  (EXP,ISO)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
diuron  (ISO)
dopamine  (ISO)
dorsomorphin  (ISO)
doxepin  (ISO)
doxorubicin  (EXP,ISO)
doxycycline  (ISO)
ebselen  (ISO)
econazole  (ISO)
elemental selenium  (ISO)
emodin  (ISO)
endosulfan  (ISO)
enoxacin  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
equilin  (ISO)
ergotamine  (ISO)
eriodictyol  (ISO)
erythrosin B  (ISO)
Estradiol 17beta-cyclopentylpropionate  (ISO)
etacrynic acid  (ISO)
ethanol  (EXP,ISO)
ethoxyquin  (ISO)
ethylbenzene  (ISO)
etoposide  (ISO)
eugenol  (ISO)
fenbendazole  (ISO)
fenofibrate  (ISO)
fipronil  (ISO)
flavonoids  (ISO)
flufenamic acid  (ISO)
flunarizine  (ISO)
Fluocinonide  (ISO)
flurotyl  (ISO)
flutamide  (ISO)
folic acid  (EXP,ISO)
folpet  (EXP)
formaldehyde  (ISO)
furan  (ISO)
galangin  (ISO)
gamma-glutamyl-glutathione  (ISO)
genistein  (EXP)
gentamycin  (ISO)
geraniol  (ISO)
glutathione  (EXP,ISO)
Goitrin  (ISO)
haloperidol  (ISO)
hemin  (ISO)
heptan-2-one  (ISO)
herbicide  (ISO)
hexachlorobenzene  (ISO)
hexachlorophene  (ISO)
homocysteine  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (EXP,ISO)
hydroxyzine  (ISO)
hypericin  (ISO)
ifosfamide  (ISO)
imipramine  (ISO)
indole-3-methanol  (EXP,ISO)
iodide salt  (ISO)
iodoquinol  (ISO)
isomethyleugenol  (ISO)
isoniazide  (ISO)
isopimpinellin  (EXP)
isothiocyanate  (ISO)
isotretinoin  (ISO)
itraconazole  (ISO)
kaempferol  (ISO)
kahweol  (ISO)
ketoconazole  (ISO)
L-cysteine  (EXP)
L-selenocysteine  (ISO)
lansoprazole  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
LY294002  (ISO)
malathion  (ISO)
maneb  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
mebendazole  (ISO)
Meclizine  (ISO)
mefenamic acid  (ISO)
MeIQx  (ISO)
melatonin  (EXP,ISO)
melphalan  (ISO)
merbromin  (ISO)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury dichloride  (ISO)
mercury(0)  (ISO)
Mesna  (EXP)
metformin  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate  (ISO)
methylarsonic acid  (ISO)
methylene blue  (ISO)
methylmercury chloride  (ISO)
microcystin  (ISO)
microcystin RR  (ISO)
microcystin-LR  (ISO)
minocycline  (ISO)
mitomycin C  (ISO)
Mitotane  (ISO)
MK 571  (ISO)
monobromobimane  (ISO)
monocrotophos  (ISO)
monosodium L-glutamate  (EXP)
N,N-diethyl-m-toluamide  (ISO)
N-acetyl-1,4-benzoquinone imine  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-hydroxy-PhIP  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosomorpholine  (ISO)
naphthalene  (EXP)
naringin  (ISO)
nefazodone  (ISO)
nevirapine  (ISO)
nicotinamide  (ISO)
nifedipine  (ISO)
nimesulide  (ISO)
nisoldipine  (ISO)
nitrendipine  (ISO)
nitrogen dioxide  (ISO)
O-acetyl-L-carnitine  (ISO)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (ISO)
okadaic acid  (EXP,ISO)
oltipraz  (EXP,ISO)
omeprazole  (ISO)
orphenadrine  (ISO)
oxaliplatin  (ISO)
oxiconazole  (ISO)
oxidopamine  (ISO)
oxybenzone  (ISO)
oxyphenbutazone  (ISO)
ozone  (ISO)
p-toluidine  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pararosaniline free base  (ISO)
parathion  (ISO)
pentachlorobenzene  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenethyl caffeate  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (ISO)
phenolphthalein  (ISO)
Phenoxybenzamine  (ISO)
phenylbutazone  (ISO)
phenylmercury acetate  (ISO)
PhIP  (EXP,ISO)
phlorizin  (EXP)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosphoramide mustard  (ISO)
phylloquinone  (ISO)
pioglitazone  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP)
platinum  (ISO)
platinum(0)  (ISO)
plumbagin  (ISO)
potassium chromate  (EXP)
potassium dichromate  (EXP)
Propiverine  (ISO)
Pyrantel pamoate  (ISO)
pyrazinecarboxamide  (ISO)
Pyridostigmine bromide  (ISO)
pyrimethamine  (ISO)
quercetin  (EXP,ISO)
quercitrin  (ISO)
quinidine  (ISO)
quinine  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
S-hexylglutathione  (ISO)
sanguinarine  (EXP,ISO)
SB 203580  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
selenomethionine  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
soybean oil  (ISO)
stavudine  (ISO)
stilbene oxide  (ISO)
streptozocin  (ISO)
styrene  (ISO)
styrene oxide  (ISO)
Sudan I  (ISO)
sulconazole  (ISO)
sulfamethoxazole  (ISO)
sulfaphenazole  (ISO)
sulfasalazine  (ISO)
sulfinpyrazone  (ISO)
sulforaphane  (EXP,ISO)
sulfotep  (ISO)
sulindac sulfide  (ISO)
sulindac sulfone  (ISO)
T-2 toxin  (ISO)
tamoxifen  (EXP,ISO)
Tanshinone I  (ISO)
tauroursodeoxycholic acid  (ISO)
temephos  (ISO)
teniposide  (ISO)
terbinafine  (ISO)
tert-butyl hydroperoxide  (EXP)
Tesaglitazar  (ISO)
Testosterone propionate  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thiabendazole  (ISO)
thioacetamide  (ISO)
thiophenes  (ISO)
thiostrepton  (ISO)
Thiotepa  (ISO)
Thonningianin A  (ISO)
Tiopronin  (ISO)
titanium dioxide  (ISO)
tolnaftate  (ISO)
toluene  (ISO)
toluene 2,4-diisocyanate  (ISO)
tranilast  (ISO)
trans-caffeic acid  (ISO)
trichostatin A  (EXP,ISO)
trimethylarsine oxide  (ISO)
triphenyl phosphate  (ISO)
Tris(1-aziridinyl)phosphine oxide  (ISO)
Tris(2,3-dibromopropyl) phosphate  (ISO)
troglitazone  (ISO)
uranium atom  (ISO)
valproic acid  (EXP,ISO)
vincaleukoblastine  (ISO)
vinclozolin  (ISO)
vincristine  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
WR-1065  (ISO)
xanthohumol  (ISO)
zerumbone  (EXP)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ regeneration  (ISO)
cellular response to cell-matrix adhesion  (ISO)
cellular response to epidermal growth factor stimulus  (ISO)
cellular response to glucocorticoid stimulus  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to lipopolysaccharide  (IDA)
common myeloid progenitor cell proliferation  (IMP)
glutathione derivative biosynthetic process  (ISO)
glutathione metabolic process  (IBA,IDA)
hepoxilin biosynthetic process  (ISO)
linoleic acid metabolic process  (ISO)
negative regulation of acute inflammatory response  (NAS)
negative regulation of apoptotic process  (TAS)
negative regulation of biosynthetic process  (ISO)
negative regulation of ERK1 and ERK2 cascade  (IDA)
negative regulation of extrinsic apoptotic signaling pathway  (ISO)
negative regulation of fibroblast proliferation  (IMP)
negative regulation of I-kappaB kinase/NF-kappaB signaling  (IDA)
negative regulation of interleukin-1 beta production  (IDA)
negative regulation of JUN kinase activity  (IDA,IMP)
negative regulation of leukocyte proliferation  (IMP)
negative regulation of MAP kinase activity  (ISO)
negative regulation of monocyte chemotactic protein-1 production  (IDA)
negative regulation of neutrophil aggregation  (NAS)
negative regulation of nitric-oxide synthase biosynthetic process  (IDA)
negative regulation of peroxidase activity  (IDA)
negative regulation of protein kinase activity  (ISO)
negative regulation of smooth muscle cell chemotaxis  (ISO)
negative regulation of stress-activated MAPK cascade  (IDA)
negative regulation of tumor necrosis factor production  (IDA)
negative regulation of vascular associated smooth muscle cell proliferation  (ISO)
oligodendrocyte development  (ISO)
positive regulation of superoxide anion generation  (IMP)
prostaglandin metabolic process  (ISO)
regulation of ERK1 and ERK2 cascade  (IDA)
regulation of stress-activated MAPK cascade  (IDA)
response to amino acid  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to L-ascorbic acid  (ISO)
response to nutrient levels  (ISO)
response to reactive oxygen species  (IDA)
response to toxic substance  (ISO)
xenobiotic metabolic process  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
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Additional References at PubMed
PMID:2388840   PMID:7982937   PMID:8135745   PMID:8145243   PMID:8584275   PMID:8605288   PMID:9446594   PMID:9511175   PMID:9560266   PMID:9730611   PMID:10349636   PMID:10922068  
PMID:10945608   PMID:11042159   PMID:11058152   PMID:11076861   PMID:11217851   PMID:11279197   PMID:11408560   PMID:11433346   PMID:12023900   PMID:12225863   PMID:12466851   PMID:12477932  
PMID:12646564   PMID:14517554   PMID:14610273   PMID:14681479   PMID:14684749   PMID:15386426   PMID:15489334   PMID:16023107   PMID:16141072   PMID:16141073   PMID:16160063   PMID:16374777  
PMID:16399382   PMID:16602821   PMID:17267597   PMID:17909032   PMID:18268004   PMID:18349876   PMID:18792812   PMID:18799693   PMID:18990698   PMID:19269317   PMID:19270193   PMID:19718438  
PMID:19739253   PMID:19915149   PMID:19935654   PMID:20404090   PMID:20538586   PMID:21134126   PMID:21267068   PMID:21748757   PMID:21873635   PMID:21975931   PMID:22022436   PMID:22084240  
PMID:22496890   PMID:22627280   PMID:22751926   PMID:22828627   PMID:22956844   PMID:23129554   PMID:23164639   PMID:23237955   PMID:23647087   PMID:24457600   PMID:24664677   PMID:25216273  
PMID:25590808   PMID:25868843   PMID:25891661   PMID:26169370   PMID:26361746   PMID:26838680   PMID:27058114   PMID:27086966   PMID:27160897   PMID:29348462   PMID:29374060   PMID:29520271  
PMID:29732603   PMID:30153066   PMID:30290218   PMID:30457570   PMID:30595499   PMID:31299423   PMID:31515511   PMID:32325033   PMID:32719131  


Genomics

Comparative Map Data
Gstp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39194,085,411 - 4,087,912 (-)NCBIGRCm39mm39
GRCm39 Ensembl194,085,407 - 4,087,985 (-)Ensembl
GRCm38194,035,411 - 4,037,912 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl194,035,407 - 4,037,985 (-)EnsemblGRCm38mm10GRCm38
MGSCv37194,035,411 - 4,037,912 (-)NCBIGRCm37mm9NCBIm37
MGSCv36194,035,411 - 4,037,912 (-)NCBImm8
Celera193,906,327 - 3,908,828 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map193.75NCBI
GSTP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1167,583,595 - 67,586,656 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1167,583,742 - 67,586,656 (+)EnsemblGRCh38hg38GRCh38
GRCh381167,583,812 - 67,586,653 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371167,351,283 - 67,354,124 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361167,107,862 - 67,110,699 (+)NCBINCBI36hg18NCBI36
Build 341167,107,861 - 67,110,699NCBI
Celera1164,685,527 - 64,688,585 (+)NCBI
Cytogenetic Map11q13.2NCBI
HuRef1163,680,236 - 63,683,230 (+)NCBIHuRef
CHM1_11167,234,118 - 67,237,177 (+)NCBICHM1_1
Gstp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21201,337,762 - 201,340,230 (-)NCBI
Rnor_6.0 Ensembl1219,291,679 - 219,294,147 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01219,291,679 - 219,294,147 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01226,162,330 - 226,164,798 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41206,627,398 - 206,629,866 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11206,780,853 - 206,783,288 (-)NCBI
Celera1198,882,807 - 198,885,275 (-)NCBICelera
Cytogenetic Map1q43NCBI
Gstp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542217,914,305 - 17,917,428 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542217,914,228 - 17,916,918 (-)NCBIChiLan1.0ChiLan1.0
GSTP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11166,253,421 - 66,256,472 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1166,253,421 - 66,256,472 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01162,942,756 - 62,945,701 (+)NCBIMhudiblu_PPA_v0panPan3
GSTP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11849,905,161 - 49,908,182 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1849,905,161 - 49,908,182 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1848,515,700 - 48,518,722 (-)NCBI
ROS_Cfam_1.01850,827,487 - 50,830,507 (-)NCBI
UMICH_Zoey_3.11850,040,622 - 50,043,638 (-)NCBI
UNSW_CanFamBas_1.01849,615,622 - 49,618,639 (-)NCBI
UU_Cfam_GSD_1.01850,409,350 - 50,412,373 (-)NCBI
Gstp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049475,755,332 - 5,758,293 (-)NCBI
SpeTri2.0NW_0049365992,197,681 - 2,200,642 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100739163
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.124,978,761 - 4,982,233 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.223,618,596 - 3,620,933 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GSTP1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.116,676,897 - 6,679,936 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120278703Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120645286Mouse
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122321310Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132362870Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132897810Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19167640035676563Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19320000035900000Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19327855120562299Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19334585237345984Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19334585237345984Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19334585237345984Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19334585237345984Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:161
Count of miRNA genes:159
Interacting mature miRNAs:161
Transcripts:ENSMUST00000169613
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000169613   ⟹   ENSMUSP00000129565
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl194,035,407 - 4,037,985 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235711
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl194,037,071 - 4,037,877 (-)Ensembl
RefSeq Acc Id: ENSMUST00000236211
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl194,035,409 - 4,035,993 (-)Ensembl
RefSeq Acc Id: ENSMUST00000236311
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl194,035,414 - 4,036,382 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237239
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl194,035,827 - 4,037,901 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237273
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl194,036,767 - 4,037,896 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237773
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl194,037,315 - 4,037,899 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237893   ⟹   ENSMUSP00000158260
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl194,035,411 - 4,037,977 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237982   ⟹   ENSMUSP00000157438
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl194,035,573 - 4,037,925 (-)Ensembl
RefSeq Acc Id: NM_013541   ⟹   NP_038569
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39194,085,411 - 4,087,912 (-)NCBI
GRCm38194,035,411 - 4,037,912 (-)ENTREZGENE
MGSCv37194,035,411 - 4,037,912 (-)RGD
Celera193,906,327 - 3,908,828 (-)RGD
cM Map19 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_038569   ⟸   NM_013541
- UniProtKB: P19157 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000157438   ⟸   ENSMUST00000237982
RefSeq Acc Id: ENSMUSP00000158260   ⟸   ENSMUST00000237893
RefSeq Acc Id: ENSMUSP00000129565   ⟸   ENSMUST00000169613
Protein Domains
GST C-terminal   GST N-terminal

Promoters
RGD ID:6830115
Promoter ID:MM_KWN:25965
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000042898
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36194,037,536 - 4,038,036 (-)MPROMDB
RGD ID:13678374
Promoter ID:EPDNEW_M23337
Type:initiation region
Name:Gstp1_1
Description:Mus musculus glutathione S-transferase, pi 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38194,037,925 - 4,037,985EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95865 AgrOrtholog
Ensembl Genes ENSMUSG00000060803 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSMUSG00000097830 UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000129565 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000138073 UniProtKB/Swiss-Prot
  ENSMUSP00000157438 UniProtKB/TrEMBL
  ENSMUSP00000158260 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000169613 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000180480 UniProtKB/Swiss-Prot
  ENSMUST00000237893 UniProtKB/TrEMBL
  ENSMUST00000237982 UniProtKB/TrEMBL
Gene3D-CATH 3.40.30.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Glutathione-S-Trfase_C-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione-S-Trfase_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione_S-Trfase UniProtKB/TrEMBL
  Glutathione_S-Trfase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_pi UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14870 UniProtKB/Swiss-Prot
MGD MGI:95865 ENTREZGENE
NCBI Gene 14870 ENTREZGENE
Pfam GST_C UniProtKB/TrEMBL
  GST_C_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB GSTP1 RGD
PhenoGen Gstp1 PhenoGen
PRINTS GSTRNSFRASEP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GST_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_NTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47616 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A494B908_MOUSE UniProtKB/TrEMBL
  A0A494BAW2_MOUSE UniProtKB/TrEMBL
  GSTP1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q8BNY4 UniProtKB/Swiss-Prot