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Gene: Mapk1 (mitogen-activated protein kinase 1) Mus musculus
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Symbol: Mapk1
Name: mitogen-activated protein kinase 1
Description: Exhibits several functions, including identical protein binding activity; phosphotyrosine residue binding activity; and protein kinase activity. Involved in several processes, including animal organ development; antigen receptor-mediated signaling pathway; and protein phosphorylation. Localizes to several cellular components, including the cytosol; mitochondrion; and pseudopodium. Used to study Weissenbacher-Zweymuller syndrome; autism spectrum disorder; and velocardiofacial syndrome. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple); pulmonary hypertension; and renal cell carcinoma. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; nervous system; and sensory organ. Orthologous to human MAPK1 (mitogen-activated protein kinase 1); PARTICIPATES IN adenosine signaling pathway; Bone morphogenetic proteins signaling pathway; ceramide signaling pathway; INTERACTS WITH (+)-catechin; (+)-pilocarpine; (+)-schisandrin B.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9030612K14Rik; AA407128; AU018647; C78273; ERK; ERK-2; Erk2; ERT1; extracellular signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; MAPK 1; MAPK 2; MAPK2; mitogen activated protein kinase 1; mitogen-activated protein kinase 2; p41mapk; p42-MAPK; p42mapk; Prkm1; PRKM2
Orthologs:
Homo sapiens (human) : MAPK1 (mitogen-activated protein kinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mapk1 (mitogen activated protein kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk1 (mitogen-activated protein kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK1 (mitogen-activated protein kinase 1)
Canis lupus familiaris (dog) : MAPK1 (mitogen-activated protein kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk1 (mitogen-activated protein kinase 1)
Sus scrofa (pig) : MAPK1 (mitogen-activated protein kinase 1)
Chlorocebus sabaeus (green monkey) : MAPK1 (mitogen-activated protein kinase 1)
Heterocephalus glaber (naked mole-rat) : Mapk1 (mitogen-activated protein kinase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1616,983,382 - 17,047,453 (+)Ensembl
GRCm381616,983,382 - 17,047,453 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371616,983,475 - 17,047,546 (+)NCBIGRCm37mm9NCBIm37
MGSCv361616,896,945 - 16,961,016 (+)NCBImm8
Celera1617,555,561 - 17,620,101 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model