Mapk1 (mitogen-activated protein kinase 1) - Rat Genome Database

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Gene: Mapk1 (mitogen-activated protein kinase 1) Mus musculus
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Symbol: Mapk1
Name: mitogen-activated protein kinase 1
RGD ID: 732503
MGI Page MGI
Description: Enables several functions, including identical protein binding activity; phosphotyrosine residue binding activity; and protein kinase activity. Involved in protein phosphorylation; response to nicotine; and transmembrane receptor protein tyrosine kinase signaling pathway. Acts upstream of or within several processes, including antigen receptor-mediated signaling pathway; embryonic organ development; and respiratory system development. Located in several cellular components, including cytosol; mitochondrion; and pseudopodium. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; nervous system; and sensory organ. Used to study Weissenbacher-Zweymuller syndrome; autism spectrum disorder; and velocardiofacial syndrome. Human ortholog(s) of this gene implicated in Noonan syndrome 13; adenocarcinoma (multiple); pulmonary hypertension; and renal cell carcinoma. Orthologous to human MAPK1 (mitogen-activated protein kinase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 9030612K14Rik; AA407128; AU018647; C78273; ERK; ERK-2; Erk2; ERT1; extracellular signal-regulated kinase 2; MAP; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; MAPK 1; MAPK 2; MAPK2; mitogen activated protein kinase 1; mitogen-activated protein kinase 2; p41mapk; p42-MAPK; p42m; p42mapk; Prk; Prkm1; PRKM2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391616,801,246 - 16,865,317 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1616,801,246 - 16,865,317 (+)EnsemblGRCm39 Ensembl
GRCm381616,983,382 - 17,047,453 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1616,983,382 - 17,047,453 (+)EnsemblGRCm38mm10GRCm38
MGSCv371616,983,475 - 17,047,546 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361616,896,945 - 16,961,016 (+)NCBIMGSCv36mm8
Celera1617,555,561 - 17,620,101 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model