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Gene: Gdf15 (growth differentiation factor 15) Mus musculus
Symbol: Gdf15
Name: growth differentiation factor 15
Description: Exhibits protein homodimerization activity. Involved in several processes, including positive regulation of myoblast fusion; reduction of food intake in response to dietary excess; and regulation of signal transduction. Localizes to extracellular region. Is expressed in several structures, including brain; duodenum; hemolymphoid system gland; liver; and placenta. Orthologous to human GDF15 (growth differentiation factor 15).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GDF-15; growth/differentiation factor 15; macrophage inhibiting cytokine-1; macrophage inhibitory cytokine 1; MIC-1; NAG-1; SBF
Homo sapiens (human) : GDF15 (growth differentiation factor 15)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gdf15 (growth differentiation factor 15)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gdf15 (growth differentiation factor 15)
Pan paniscus (bonobo/pygmy chimpanzee) : GDF15 (growth differentiation factor 15)
Canis lupus familiaris (dog) : GDF15 (growth differentiation factor 15)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gdf15 (growth differentiation factor 15)
Sus scrofa (pig) : GDF15 (growth differentiation factor 15)
Chlorocebus sabaeus (African green monkey) : GDF15 (growth differentiation factor 15)
Heterocephalus glaber (naked mole-rat) : Gdf15 (growth differentiation factor 15)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl870,629,393 - 70,632,456 (-)EnsemblGRCm38mm10GRCm38
GRCm38870,629,393 - 70,632,470 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37873,153,293 - 73,155,534 (-)NCBIGRCm37mm9NCBIm37
MGSCv36873,558,382 - 73,561,082 (-)NCBImm8
Celera873,186,175 - 73,188,416 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gdf15
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735622
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-07-21
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.