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Gene: Gdf15 (growth differentiation factor 15) Mus musculus
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Symbol: Gdf15
Name: growth differentiation factor 15
Description: Exhibits protein homodimerization activity. Involved in several processes, including positive regulation of myoblast fusion; reduction of food intake in response to dietary excess; and regulation of signal transduction. Localizes to extracellular region. Is expressed in several structures, including brain; duodenum; hemolymphoid system gland; liver; and placenta. Orthologous to human GDF15 (growth differentiation factor 15).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GDF-15; growth/differentiation factor 15; macrophage inhibiting cytokine-1; macrophage inhibitory cytokine 1; MIC-1; NAG-1; SBF
Orthologs:
Homo sapiens (human) : GDF15 (growth differentiation factor 15)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gdf15 (growth differentiation factor 15)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gdf15 (growth differentiation factor 15)
Pan paniscus (bonobo/pygmy chimpanzee) : GDF15 (growth differentiation factor 15)
Canis lupus familiaris (dog) : GDF15 (growth differentiation factor 15)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gdf15 (growth differentiation factor 15)
Sus scrofa (pig) : GDF15 (growth differentiation factor 15)
Chlorocebus sabaeus (African green monkey) : GDF15 (growth differentiation factor 15)
Heterocephalus glaber (naked mole-rat) : Gdf15 (growth differentiation factor 15)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl870,629,393 - 70,632,456 (-)EnsemblGRCm38mm10GRCm38
GRCm38870,629,393 - 70,632,470 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37873,153,293 - 73,155,534 (-)NCBIGRCm37mm9NCBIm37
MGSCv36873,558,382 - 73,561,082 (-)NCBImm8
Celera873,186,175 - 73,188,416 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gdf15
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735622
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-07-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.